Robert G Dennis

Works (1)

Updated: July 5th, 2023 15:38

2015 journal article

Development of a Cyclic Strain Bioreactor for Mechanical Enhancement and Assessment of Bioengineered Myocardial Constructs

CARDIOVASCULAR ENGINEERING AND TECHNOLOGY, 6(4), 533–545.

By: B. Salazar *, A. Cashion n, R. Dennis n & R. Birla*

author keywords: Biomedical transducers; Microcontrollers; Printed circuits; Micropositioning voice-coil actuator; Cardiac tissue engineering; Artificial heart muscle; Bioreactors
MeSH headings : Animals; Bioreactors; Cells, Cultured; Collagen Type I / metabolism; Equipment Design; Fibrin / chemistry; Mechanical Phenomena; Myocardial Contraction / physiology; Myocardium / cytology; Myocardium / metabolism; Myocytes, Cardiac / physiology; Rats; Software; Tissue Engineering / instrumentation; Tissue Scaffolds
TL;DR: The effectiveness of a new bioreactor design to improve contractility of engineered cardiac muscle tissue is demonstrated and an increase in contractile force was observed after the strain protocol of 10% stretch at 1 Hz, with no significant increase observed in the control group. (via Semantic Scholar)
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Added: August 6, 2018

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