Robert Graham Franks

Plant Development, Molecular Genetics

Works (46)

Updated: November 28th, 2024 05:03

2024 journal article

Machine Learning Inference of Gene Regulatory Networks in Developing Mimulus Seeds

Plants.

By: A. Tucci, M. Flores-Vergara & R. Franks 

Source: ORCID
Added: November 25, 2024

2023 article

Assessing the role of REM13, REM34 and REM46 during the transition to the reproductive phase in Arabidopsis thaliana

Manrique, S., Caselli, F., Matias-Hernandez, L., Franks, R. G., Colombo, L., & Gregis, V. (2023, May 12). PLANT MOLECULAR BIOLOGY, Vol. 5.

By: S. Manrique *, F. Caselli *, L. Matias-Hernandez *, R. Franks n , L. Colombo * & V. Gregis *

author keywords: REM transcription factor; Flowering time; Cell division; Co-expression analysis; Protein interaction; Arabidopsis thaliana
TL;DR: It is suggested that three REM genes have a role in flowering time regulation and may modulate cell cycle progression and protein interaction experiments revealed that REM34 and REM46 interact with each other, suggesting that they might work cooperatively to regulate cell division during inflorescence meristem commitment. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: May 30, 2023

2023 article

HISTONE DEACETYLASE19 Controls Ovule Number Determination and Transmitting Tract Differentiation

Manrique, S., Cavalleri, A., Guazzotti, A., Villarino, G. H., Simonini, S., Bombarely, A., … Colombo, L. (2023, December 7). PLANT PHYSIOLOGY, Vol. 12.

By: S. Manrique *, A. Cavalleri *, A. Guazzotti *, G. Villarino n, S. Simonini *, A. Bombarely *, T. Higashiyama *, U. Grossniklaus * ...

TL;DR: Factors required for the downregulation of STM in the CMM, which is necessary for organogenesis and tissue differentiation, are identified. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
15. Life on Land (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: December 18, 2023

2020 journal article

Developmental Analysis of Mimulus Seed Transcriptomes Reveals Functional Gene Expression Clusters and Four Imprinted, Endosperm-Expressed Genes

Frontiers in Plant Science, 11.

By: M. Flores-Vergara  n, E. Oneal *, M. Costa *, G. Villarino *, C. Roberts*, M. Balaguer n, S. Coimbra *, J. Willis *, R. Franks n 

author keywords: seed development; ribonucleic acid sequencing; developmental time course analysis; endosperm; genomic imprinting; K-means clustering; MADS-box genes; Mimulus guttatus
TL;DR: This study is the first to validate genes with imprinted endosperm expression in Mimulus guttatus, and will inform future studies on the genetic causes of seed failure in this model system. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
Source: ORCID
Added: February 9, 2023

2019 journal article

Functional characterization of Terminal Flower1 homolog in Cornus canadensis by genetic transformation

Plant Cell Reports, 38(3), 333–343.

By: X. Liu  n, J. Zhang  n, D. Xie n , R. Franks n  & Q. Xiang n 

author keywords: Cornus canadensis; CorcanTFL1; Genetic transformation; Inflorescence development; Organ conversion
MeSH headings : Cornus / genetics; Cornus / metabolism; Gene Expression Regulation, Plant / genetics; Gene Expression Regulation, Plant / physiology; Inflorescence / genetics; Inflorescence / metabolism; Phylogeny; Plant Proteins / genetics; Plant Proteins / metabolism
TL;DR: Observations support an important role of CorcanTFL1 in determining flowering time and the morphological destinies of leaves and buds at the node bearing the inflorescence in Cornus canadensis. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
Sources: ORCID, Crossref, NC State University Libraries
Added: January 23, 2019

2017 journal article

Redundant CArG Box Cis-motif Activity Mediates SHATTERPROOF2 Transcriptional Regulation during Arabidopsis thaliana Gynoecium Development

FRONTIERS IN PLANT SCIENCE, 8.

By: B. Sehra n & R. Franks n 

Contributors: B. Sehra n & R. Franks n 

author keywords: SHATTERPROOF genes; FRUITFULL; seedpod dehiscence; valve margin; fruit patterning; transcriptional regulation
TL;DR: Two separable, independent cis-regulatory modules are identified, a 1kb promoter region and a 700bp enhancer region, that are capable of giving VM and DZ expression and may contribute to the robustness of SHP2 expression in this tissue. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2016 journal article

Alterations of CorTFL1 and CorAP1 expression correlate with major evolutionary shifts of inflorescence architecture in Cornus (Cornaceae) - a proposed model for variation of closed inflorescence forms

New Phytologist, 216(2), 519–535.

By: Q. Ma  n, X. Liu n, R. Franks n  & Q. Xiang n 

Contributors: Q. Ma  n, X. Liu n, R. Franks n  & Q. Xiang  n

author keywords: CorAP1; Cornus; CorTFL1; evolutionary development; gene expression; inflorescence; in situ hybridization; quantitative real-time polymerase chain reaction (qRT-PCR)
MeSH headings : Biological Evolution; Cornaceae / anatomy & histology; Cornaceae / genetics; Cornaceae / growth & development; Gene Expression Regulation, Developmental; Gene Expression Regulation, Plant; In Situ Hybridization; Inflorescence / anatomy & histology; Inflorescence / genetics; Models, Biological; Models, Genetic; Phylogeny; Plant Proteins / genetics; Plant Proteins / metabolism; Real-Time Polymerase Chain Reaction; Species Specificity
TL;DR: The study found a clear correlation between the expression patterns of CorTFL1 and CorAP1 and the inflorescence architecture in a natural system displaying closed inflorescences and proposes that a TFL1-like and AP1- like gene-based model may explain variation of closed inflorescenceences in Cornus and other lineages. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018

2016 journal article

Analysis of two TFL1 homologs of dogwood species (Cornus L.) indicates functional conservation in control of transition to flowering

Planta, 243(5), 1129–1141.

By: X. Liu n, J. Zhang *, A. Abuahmad n, R. Franks n , D. Xie n  & Q. Xiang n 

Contributors: X. Liu n, J. Zhang *, A. Abuahmad n, R. Franks n , D. Xie n  & Q. Xiang n 

author keywords: Cornus; TERMINAL FLOWER 1 (TFL1); Genetic transformation; Flowering time; Inflorescence architecture
MeSH headings : Arabidopsis / genetics; Arabidopsis Proteins / genetics; Arabidopsis Proteins / metabolism; Cloning, Molecular; Cornus / genetics; Cornus / physiology; Flowers / genetics; Flowers / physiology; Gene Expression Regulation, Plant; Inflorescence / genetics; Mutation; Phylogeny; Plant Proteins / genetics; Plant Proteins / metabolism; Plants, Genetically Modified; Sequence Homology, Amino Acid
TL;DR: The role of TFL1 homologs of Cornus L. canadensis in regulating the transition to reproductive development in Arabidopsis is reported and data indicate that CorfloTFL1 and CorcanTfl1 have conserved the ancestral function of Tfl1 and CEN regulating flowering time and inflorescence determinacy. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
15. Life on Land (OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018

2016 journal article

Analysis of two TFL1 homologs of dogwood species (Cornus L.) indicates functional conservation in control of transition to flowering.

http://europepmc.org/abstract/med/26825444

By: X. Liu, J. Zhang, A. Abuahmad, R. Franks , D. Xie, Q. Xiang, Planta

europepmc.org
Source: ORCID
Added: January 22, 2019

2016 journal article

Disruption of endosperm development is a major cause of hybrid seed inviability between Mimulus guttatus and Mimulus nudatus

NEW PHYTOLOGIST, 210(3), 1107–1120.

By: E. Oneal *, J. Willis * & R. Franks n 

Contributors: E. Oneal *, J. Willis * & R. Franks n 

author keywords: endosperm; hybrid inviability; Mimulus guttatus (monkeyflower); pollen-pistil interactions; postzygotic isolation; seed development
MeSH headings : Crosses, Genetic; Endosperm / embryology; Fruit / growth & development; Germination; Hybridization, Genetic; Mimulus / embryology; Mimulus / genetics; Phenotype; Pollen Tube / growth & development; Self-Fertilization; Staining and Labeling; Sympatry
TL;DR: Light is shed on the extent of developmental variation between closely related species within the M. guttatus species complex, an important ecological model system, and a partial mechanism for the hybrid barrier between M. Guttatus and M. nudatus is provided. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
15. Life on Land (OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2016 article

Histological Analysis of the Arabidopsis Gynoecium and Ovules Using Chloral Hydrate Clearing and Differential Interference Contrast Light Microscopy

OOGENESIS: METHODS AND PROTOCOLS, Vol. 1457, pp. 1–7.

By: R. Franks n 

Contributors: R. Franks n 

author keywords: Ovule; Chloral hydrate; Nomarski optics; Ovary; Seed development; Seedpod
MeSH headings : Arabidopsis / cytology; Arabidopsis / physiology; Chloral Hydrate; Cytological Techniques; Microscopy, Interference; Ovule / cytology
TL;DR: The use of chloral hydrate optical clearing paired with differential interference contrast microscopy allows the analysis of internal structures of developing plant organs without the need for paraffin embedding and sectioning. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2016 journal article

SEUSS Integrates Gibberellin Signaling with Transcriptional Inputs from the SHR-SCR-SCL3 Module to Regulate Middle Cortex Formation in the Arabidopsis Root

PLANT PHYSIOLOGY, 170(3), 1675–1683.

By: X. Gong *, M. Flores-Vergara n, J. Hong *, H. Chu *, J. Lim *, R. Franks n , Z. Liu *, J. Xu *, P. physiology

Contributors: X. Gong *, M. Flores-Vergara n, J. Hong *, H. Chu *, J. Lim *, R. Franks n , Z. Liu *, J. Xu *

MeSH headings : Arabidopsis / cytology; Arabidopsis / genetics; Arabidopsis / metabolism; Arabidopsis Proteins / genetics; Arabidopsis Proteins / metabolism; Co-Repressor Proteins / genetics; Co-Repressor Proteins / metabolism; Epistasis, Genetic; Gene Expression Regulation, Plant; Gibberellins / metabolism; Microscopy, Confocal; Models, Genetic; Mutation; Plant Roots / cytology; Plant Roots / genetics; Plant Roots / metabolism; Plants, Genetically Modified; Protein Binding; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Transcription Factors / genetics; Transcription Factors / metabolism; Two-Hybrid System Techniques
TL;DR: This study identifies SEU as a new critical player that integrates GA signaling with transcriptional inputs from the SHR-SCR-SCL3 module to regulate MC formation in the Arabidopsis root. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2016 journal article

SEUSS integrates gibberellin signaling with transcriptional inputs from the SHR-SCR-SCL3 module to regulate middle cortex formation in the Arabidopsis root.

Plant Physiology. http://europepmc.org/abstract/med/26818732

By: X. Gong, M. Flores-Vergara, J. Hong, H. Chu, J. Lim, R. Franks , Z. Liu, J. Xu

europepmc.org
Source: ORCID
Added: January 22, 2019

2016 journal article

Transcriptomic Signature of the SHATTERPROOF2 Expression Domain Reveals the Meristematic Nature of Arabidopsis Gynoecial Medial Domain

PLANT PHYSIOLOGY, 171(1), 42–61.

By: G. Villarino n, Q. Hu n, S. Manrique *, M. Flores-Vergara n, B. Sehra n, L. Robles n, J. Brumos  n, A. Stepanova n  ...

Contributors: G. Villarino n, Q. Hu n, S. Manrique *, M. Flores-Vergara n, B. Sehra n, L. Robles n, J. Brumos  n, A. Stepanova n  ...

MeSH headings : Arabidopsis / anatomy & histology; Arabidopsis / genetics; Arabidopsis Proteins / genetics; Arabidopsis Proteins / isolation & purification; Base Sequence; Chloral Hydrate; DNA, Antisense; Flowers / genetics; Gene Expression Regulation, Plant; Genome, Plant; In Situ Hybridization; Indoleacetic Acids / pharmacology; MADS Domain Proteins / genetics; MADS Domain Proteins / isolation & purification; Meristem / genetics; Meristem / growth & development; Meristem / metabolism; Microscopy, Confocal; Ovule / cytology; Ovule / growth & development; Ovule / metabolism; Protein Isoforms; Protoplasts; RNA, Plant / chemistry; RNA, Plant / isolation & purification; Seeds / growth & development; Sequence Alignment; Transcription Factors; Transcriptional Activation; Transcriptome
TL;DR: A novel approach to analyze the transcriptional signature of the medial domain of the Arabidopsis gynoecium, highlighting the developmental stages that immediately proceed ovule initiation, the earliest stages of seed development and identifying additional genes including novel isoforms, cis-natural antisense transcripts, and a previously unrecognized member of the REPRODUCTIVE MERISTEM family of transcriptional regulators that are potential novel regulators of medial domain development. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2015 review

Auxin and cytokinin act during gynoecial patterning and the development of ovules from the meristematic medial domain

[Review of ]. WILEY INTERDISCIPLINARY REVIEWS-DEVELOPMENTAL BIOLOGY, 4(6), 555–571.

By: B. Sehra n & R. Franks n 

Contributors: B. Sehra n & R. Franks n 

MeSH headings : Arabidopsis / genetics; Arabidopsis / growth & development; Cytokinins / metabolism; Gene Expression Regulation, Plant / physiology; Indoleacetic Acids / metabolism; Meristem / growth & development; Meristem / metabolism; Ovule / growth & development; Ovule / metabolism
TL;DR: This review focuses on molecular aspects of the development of the Arabidopsis thaliana gynoecium, and highlights what has been learned recently with respect to the role of auxin. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science; OpenAlex)
13. Climate Action (Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2015 article

Molecular basis of fruit development

Liu, Z., & Franks, R. G. (2015, February 5). FRONTIERS IN PLANT SCIENCE, Vol. 6.

By: Z. Liu * & R. Franks n 

Contributors: Z. Liu * & R. Franks n 

author keywords: fruit evolution; endocarp; auxin; cytokinin; morphogenesis; ovule; gynoecium; carpel margin meristem
TL;DR: The 11 articles within this special research topic focus on the molecular mechanisms of early fruit development and span a diversity of species and experimental approaches. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science; OpenAlex)
13. Climate Action (Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2015 book

Molecular basis of fruit development

In Frontiers Research Topics.

Robert Franks

Ed(s): Z. Liu & R. Franks 

UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Source: ORCID
Added: January 22, 2019

2014 article

Corrigendum: [Novel functional roles for PERIANTHIA and SEUSS during floral organ identity specification, floral meristem termination and gynoecial development]

Franks, R. G. (2014, August 29). FRONTIERS IN PLANT SCIENCE, Vol. 5.

By: R. Franks n 

author keywords: corrigendum; hoyers; chloral hydrate; PERIANTHIA; SEUSS
TL;DR: A functional role for the transcription factor PERIANTHIA (PAN) is reported in the development of the gynoecial medial domain and the formation of ovule primordia, indicating that PAN functions as an activator or repressor of AG expression in a whorl-specific fashion. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2014 book

Flower development: Open questions and future directions

In Methods in Molecular Biology (Vol. 1110, pp. 103–124).

Contributors: F. Wellmer, J. Bowman, B. Davies, C. Ferrándiz, J. Fletcher, R. Franks , E. Graciet, V. Gregis ...

MeSH headings : Evolution, Molecular; Flowers / anatomy & histology; Flowers / genetics; Flowers / growth & development; Meristem / anatomy & histology; Meristem / genetics; Meristem / growth & development; Models, Biological
Source: ORCID
Added: January 22, 2019

2014 journal article

Novel functional roles for PERIANTHIA and SEUSS during floral organ identity specification, floral meristem termination, and gynoecial development

Frontiers in Plant Science, 5(APR).

By: A. Wynn n, A. Seaman n, A. Jones n & R. Franks n 

Contributors: A. Wynn n, A. Seaman n, A. Jones n & R. Franks n 

author keywords: ovule; gynoecium; flowers; agamous; wuschel; organ identity; indeterminate growth
TL;DR: A functional role for the transcription factor PERIANTHIA (PAN) is reported in the development of the gynoecial medial domain and the formation of ovule primordia, indicating that PAN functions as an activator or repressor of AG expression in a whorl-specific fashion. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
Sources: ORCID, NC State University Libraries, NC State University Libraries
Added: August 6, 2018

2014 journal article

Polar Auxin Transport Is Essential for Medial versus Lateral Tissue Specification and Vascular-Mediated Valve Outgrowth in Arabidopsis Gynoecia[W]

PLANT PHYSIOLOGY, 166(4), 1998–U1237.

By: E. Larsson *, C. Roberts*, A. Claes *, R. Franks n  & E. Sundberg *

Contributors: E. Larsson *, C. Roberts*, A. Claes *, R. Franks n  & E. Sundberg *

MeSH headings : Arabidopsis / embryology; Arabidopsis / metabolism; Arabidopsis Proteins / genetics; Arabidopsis Proteins / metabolism; Biological Transport; Indoleacetic Acids / metabolism; Membrane Transport Proteins / genetics; Membrane Transport Proteins / metabolism; Plant Growth Regulators / metabolism; Reproduction
TL;DR: A new model of auxin-mediated gynoecial patterning is proposed, suggesting that valve outgrowth depends on PIN1-mediated lateral auxin maxima as well as subsequent internal auxin drainage and provascular formation, whereas the growth of the medial domains is less dependent on correct PAT. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2014 journal article

Tissue-specific gene expression in maize seeds during colonization by Aspergillus flavus and Fusarium verticillioides

MOLECULAR PLANT PATHOLOGY, 16(7), 662–674.

By: X. Shu  n, D. Livingston n, R. Franks n , R. Boston n, C. Woloshuk * & G. Payne n

Contributors: X. Shu  n, D. Livingston n, R. Franks n , R. Boston n, C. Woloshuk * & G. Payne n

author keywords: Aspergillus flavus; Fusarium verticillioides; histology; maize; PRms; RNAinsitu hybridization; Sh1
MeSH headings : Aspergillus flavus / pathogenicity; Fusarium / pathogenicity; Seeds / metabolism; Zea mays / embryology; Zea mays / microbiology
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2013 review

Auxin and the Arabidopsis thaliana gynoecium

[Review of ]. JOURNAL OF EXPERIMENTAL BOTANY, 64(9), 2619–2627.

By: E. Larsson *, R. Franks n  & E. Sundberg *

Contributors: E. Larsson *, R. Franks n  & E. Sundberg *

author keywords: Arabidopsis; auxin; development; female reproductive organ; gynoecium; patterning
MeSH headings : Arabidopsis / growth & development; Arabidopsis / metabolism; Arabidopsis Proteins / metabolism; Arabidopsis Proteins / physiology; Flowers / growth & development; Flowers / metabolism; Homeostasis; Indoleacetic Acids / metabolism; Plant Growth Regulators / metabolism
TL;DR: This review summarizes recent advances in understanding of how auxin biosynthesis, transport, and responses together generate specific gynoecial domains and highlights areas where future research endeavours are likely to provide additional insight into the homeostatic molecular mechanisms by which auxin regulates gynOecium development. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2013 journal article

Characterization of the sequence and expression pattern of LFY homologues from dogwood species (Cornus) with divergent inflorescence architectures

Annals of Botany, 112(8), 1629–1641.

By: J. Liu n, R. Franks n , C. Feng n, X. Liu n, C. Fu * & Q. (Jenny) Xiang

Contributors: J. Liu n, R. Franks n , C. Feng n, X. Liu n, C. Fu * & Q. Xiang n 

author keywords: Cornus; dogwood; inflorescence evolution; LFY homologues; CorLFY expression; RTPCR; in situ hybridization
MeSH headings : Amino Acid Sequence; Base Sequence; Cornus / anatomy & histology; Cornus / genetics; Cornus / growth & development; Exons / genetics; Gene Expression Regulation, Developmental; Gene Expression Regulation, Plant; Genes, Plant; In Situ Hybridization; Inflorescence / anatomy & histology; Inflorescence / genetics; Inflorescence / growth & development; Molecular Sequence Data; Phylogeny; Plant Proteins / chemistry; Plant Proteins / genetics; Plant Proteins / metabolism; Sequence Homology, Amino Acid
TL;DR: A role for CorLFY genes during floral and inflorescence development in dogwoods is suggested, however, the failure to detect expression differences between the inflorescence types in the Cornus species analysed suggests that the evolutionary shift between major inflorescencetypes in the genus is not controlled by dramatic alterations in the levels of CorL FY gene transcript accumulation. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
15. Life on Land (OpenAlex)
Sources: ORCID, Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2013 journal article

De novo Sequencing, Characterization, and Comparison of Inflorescence Transcriptomes of Cornus canadensis and C. florida (Cornaceae)

PLoS ONE, 8(12), e82674.

By: J. Zhang  n, R. Franks n , X. Liu n, M. Kang *, J. Keebler n, J. Schaff n, H. Huang*, Q. Xiang n 

Contributors: J. Zhang  n, R. Franks n , X. Liu n, M. Kang *, J. Keebler n, J. Schaff n, H. Huang*, Q. Xiang n 

Ed(s): T. Wang

MeSH headings : Chromosome Mapping; Cornus / genetics; Cornus / growth & development; DNA, Complementary / chemistry; Flowers / genetics; Flowers / growth & development; Gene Library; Polymorphism, Single Nucleotide; Sequence Analysis, DNA; Transcriptome
TL;DR: The study identified putative candidates potentially involved in the genetic regulation of inflorescence evolution and/or disease resistance in dogwoods for future analyses, and built a preliminary source of genome sequence data. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
15. Life on Land (OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018

2013 book

Scanning Electron Microscopy analysis of floral development

In Methods in Molecular Biology (Vol. 1110, pp. 263–273).

By: R. Franks n 

Contributors: R. Franks n 

MeSH headings : Flowers / cytology; Flowers / growth & development; Flowers / ultrastructure; Microscopy, Electron, Scanning / methods; Molecular Imaging; Tissue Fixation
TL;DR: Scanning Electron Microscopy allows the morphological characterization of the surface features of floral and inflorescence structures in a manner that retains the topography or three-dimensional appearance of the structure. (via Semantic Scholar)
Source: ORCID
Added: January 22, 2019

2013 journal article

The arabidopsis thaliana GRF-interacting factor gene family plays an essential role in control of male and female reproductive development

Developmental Biology, 386(1), 12–24.

By: B. Lee *, A. Wynn n, R. Franks n , Y. Hwang *, J. Lim * & J. Kim *

Contributors: B. Lee *, A. Wynn n, R. Franks n , Y. Hwang *, J. Lim * & J. Kim *

author keywords: Arabidopsis thaliana; GRF-INTERACTING FACTOR; Carpel; Anther; Cell specification
MeSH headings : Arabidopsis / genetics; Arabidopsis / growth & development; Arabidopsis Proteins / metabolism; Flowers / growth & development; Gene Expression Regulation, Plant; Meristem / growth & development; Microscopy, Electron, Scanning; Microscopy, Interference; Multigene Family; Mutation; Ovule / growth & development; Phenotype; Plant Infertility; Plants, Genetically Modified; Pollen / growth & development; Trans-Activators / genetics; Trans-Activators / metabolism
TL;DR: It is proposed that the GIF family of Arabidopsis is a novel and essential component required for the cell specification maintenance during reproductive organ development and, ultimately, for the reproductive competence. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
Source: ORCID
Added: January 22, 2019

2012 journal article

Evolution of bract development and B‐class MADS box gene expression in petaloid bracts of Cornus s. l. (Cornaceae)

New Phytologist, 196(2), 631–643.

By: C. Feng n, X. Liu n, Y. Yu  n, D. Xie n , R. Franks n  & Q. Xiang n 

Contributors: C. Feng n, X. Liu n, Y. Yu  n, D. Xie n , R. Franks n  & Q. Xiang  n

author keywords: APETALA3; B-class gene expression; Cornus; development; Evo-Devo; evolution of petaloid bracts; heterotopic petaloidy; PISTILLATA
MeSH headings : Biological Evolution; Cell Shape; Cornaceae / anatomy & histology; Cornaceae / genetics; Cornaceae / growth & development; Cornaceae / ultrastructure; Flowers / cytology; Flowers / genetics; Flowers / growth & development; Flowers / ultrastructure; Gene Expression Regulation, Developmental; Gene Expression Regulation, Plant; Genes, Plant / genetics; Inflorescence / growth & development; MADS Domain Proteins / genetics; MADS Domain Proteins / metabolism; Phylogeny; Plant Epidermis / cytology; Plant Epidermis / ultrastructure; Plant Leaves / cytology; Plant Leaves / genetics; Plant Leaves / growth & development; Plant Leaves / ultrastructure; Plant Proteins / genetics; Plant Proteins / metabolism; Seasons; Time Factors
TL;DR: Phylogeny-based analysis identified developmental and gene expression changes that are correlated with the evolution of petaloid bracts in C. florida and C. canadensis, and it is suggested that functional transference within B-class gene families may have contributed to the origin of bract petaloids in these species. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
15. Life on Land (OpenAlex)
Sources: ORCID, Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2012 journal article

Plant regeneration and genetic transformation of C. canadensis: a non-model plant appropriate for investigation of flower development in Cornus (Cornaceae)

Plant Cell Reports, 32(1), 77–87.

By: X. Liu n, C. Feng n, R. Franks n , R. Qu n, D. Xie n  & Q. Xiang n 

Contributors: X. Liu n, C. Feng n, R. Franks n , R. Qu n, D. Xie n  & Q. Xiang  n

MeSH headings : Cornus / drug effects; Cornus / genetics; Cornus / growth & development; Flowers / drug effects; Flowers / genetics; Flowers / growth & development; Fluorescence; Gene Expression Regulation, Plant; Green Fluorescent Proteins / metabolism; Hygromycin B / pharmacology; Inflorescence / drug effects; Inflorescence / growth & development; Microscopy, Confocal; Models, Biological; Plant Shoots / drug effects; Plant Shoots / growth & development; Regeneration / drug effects; Reverse Transcriptase Polymerase Chain Reaction; Soil; Transformation, Genetic / drug effects
TL;DR: An effective protocol of plant regeneration and genetic transformation of C. canadensis via Agrobacterium strain EHA105-mediated transformation is reported, providing an appropriate platform to investigate the molecular mechanisms by which the various inflorescence forms are developed in Cornus plants. (via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land (Web of Science; OpenAlex)
Sources: NC State University Libraries, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018

2011 journal article

Phylogeny-based developmental analyses illuminate evolution of inflorescence architectures in dogwoods (Cornus s. l., Cornaceae)

NEW PHYTOLOGIST, 191(3), 850–869.

By: C. Feng n, Q. Xiang n  & R. Franks n 

Contributors: C. Feng n, Q. Xiang  n & R. Franks n 

author keywords: ancestral character state reconstruction; Cornus; evolutionary development; inflorescence evolution; umbels and heads
MeSH headings : Biological Evolution; Cornus / genetics; Cornus / growth & development; Cornus / ultrastructure; Inflorescence / genetics; Inflorescence / growth & development; Inflorescence / ultrastructure; Meristem / genetics; Meristem / growth & development; Meristem / ultrastructure; Organogenesis / genetics; Phylogeny; Reproduction / physiology
TL;DR: The results indicate that heads and umbels evolved independently in Cornus from elongated forms via an umbellate dichasium ancestor and this process involved several independent changes. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
15. Life on Land (OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2011 journal article

Transcriptomic Characterization of a Synergistic Genetic Interaction during Carpel Margin Meristem Development in Arabidopsis thaliana

PLOS ONE, 6(10).

By: A. Wynn n, E. Rueschhoff * & R. Franks n 

Contributors: A. Wynn n, E. Rueschhoff * & R. Franks n 

MeSH headings : Arabidopsis / genetics; Arabidopsis / growth & development; Arabidopsis / metabolism; Arabidopsis Proteins / genetics; Arabidopsis Proteins / metabolism; Flowers / genetics; Flowers / growth & development; Flowers / metabolism; Gene Expression Regulation, Developmental / genetics; Gene Expression Regulation, Developmental / physiology; Gene Expression Regulation, Plant / genetics; Gene Expression Regulation, Plant / physiology; In Situ Hybridization; Meristem / genetics; Meristem / growth & development; Meristem / metabolism; Plants, Genetically Modified / genetics; Plants, Genetically Modified / growth & development; Plants, Genetically Modified / metabolism; Protein Binding; Transcription Factors / genetics; Transcription Factors / metabolism
TL;DR: This study identifies a diverse set of transcripts that display altered expression in the seu ant double mutant tissues and identifies the regulatory hierarchy controlled by SEU and ANT that will clarify the molecular mechanism of the functional redundancy of these two genes and illuminate the developmental and molecular events required for CMM development and ovule initiation. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2010 journal article

Polar auxin transport together with AINTEGUMENTA and REVOLUTA coordinate early Arabidopsis gynoecium development

DEVELOPMENTAL BIOLOGY, 346(2), 181–195.

By: S. Note-Wilson, S. Azhakanandam n & R. Franks n 

Contributors: S. Nole-Wilson n, S. Azhakanandam n & R. Franks n 

author keywords: NPA; Replum; Carpel margin meristem; TAA1; PHABULOSA; Homeodomain-leucine zipper
MeSH headings : Arabidopsis / genetics; Arabidopsis / growth & development; Arabidopsis Proteins / genetics; Arabidopsis Proteins / metabolism; Biological Transport / physiology; Flowers / growth & development; Gene Expression Regulation, Plant; Indoleacetic Acids / metabolism; Mutation; Phenotype; Transcription Factors / genetics; Transcription Factors / metabolism
TL;DR: It is demonstrated that auxin transport is required for the development of the medial ovary domain that contains the carpel margin meristem, a vital female reproductive structure, and suggested that an auxin-mediated positional cue is important for the differential specification ofThe medial and lateral ovary domains. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2010 journal article

Synergistic disruptions in seuss cyp85A2 double mutants reveal a role for brassinolide synthesis during gynoecium and ovule development

BMC PLANT BIOLOGY, 10.

By: S. Nole-Wilson n, E. Rueschhoff n, H. Bhatti n & R. Franks n 

Contributors: S. Nole-Wilson n, E. Rueschhoff n, H. Bhatti n & R. Franks n 

MeSH headings : Arabidopsis / genetics; Arabidopsis / growth & development; Arabidopsis Proteins / genetics; Arabidopsis Proteins / metabolism; Brassinosteroids; Cholestanols / metabolism; Chromosome Mapping; Cytochrome P-450 Enzyme System / genetics; Cytochrome P-450 Enzyme System / metabolism; DNA, Plant / genetics; Gene Expression Regulation, Developmental; Gene Expression Regulation, Plant; Genetic Complementation Test; Genotype; Mutagenesis, Insertional; Mutation; Ovule / growth & development; Plant Growth Regulators / biosynthesis; Steroids, Heterocyclic / metabolism
TL;DR: The identification of mutations in CYP85A2 as enhancers of the seuss mutant phenotype suggests a previously unrecognized role for brassinolide synthesis in gynoecial and ovule outer integument development and suggests that seuss mutants may be more sensitive to the loss or reduction of brassinlide synthesis than are wild type plants. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2009 journal article

SEUSS and SEUSS-LIKE Transcriptional Adaptors Regulate Floral and Embryonic Development in Arabidopsis

PLANT PHYSIOLOGY, 152(2), 821–836.

By: F. Bao n, S. Azhakanandam n & R. Franks n 

Contributors: F. Bao n, S. Azhakanandam n & R. Franks n 

MeSH headings : Amino Acid Sequence; Arabidopsis / genetics; Arabidopsis / growth & development; Arabidopsis Proteins / genetics; Arabidopsis Proteins / metabolism; Flowers / growth & development; Gene Expression Regulation, Plant; Indoleacetic Acids / metabolism; Molecular Sequence Data; Mutation; Phylogeny; Plant Roots / growth & development; Transcription Factors / genetics; Transcription Factors / metabolism
TL;DR: It is demonstrated that SLK gene function is required for proper development of vital female reproductive tissues derived from the carpel margin and a model that posits that SEU and SLK genes support organ development from meristematic regions through two different pathways is proposed. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2008 journal article

SEUSS and AINTEGUMENTA mediate patterning and ovule initiation during gynoecium medial domain development

PLANT PHYSIOLOGY, 146(3), 1165–1181.

By: S. Azhakanandam n, S. Nole-Wilson n, F. Bao n & R. Franks n 

Contributors: S. Azhakanandam n, S. Nole-Wilson n, F. Bao n & R. Franks n 

MeSH headings : Arabidopsis / genetics; Arabidopsis / growth & development; Arabidopsis / metabolism; Arabidopsis Proteins / genetics; Arabidopsis Proteins / metabolism; Body Patterning / physiology; Cell Nucleus / metabolism; Flowers / growth & development; Flowers / metabolism; Gene Expression; Homeodomain Proteins / metabolism; Mutation; Phenotype; Transcription Factors / genetics; Transcription Factors / metabolism
TL;DR: A synergistic genetic interaction between seuss and aintegumenta mutants resulting in a complete loss of ovule initiation and a reduction of the structures derived from the medial domain is reported. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2006 journal article

SEUSS and LEUNIG regulate cell proliferation, vascular development and organ polarity in Arabidopsis petals

PLANTA, 224(4), 801–811.

By: R. Franks n , Z. Liu * & R. Fischer *

Contributors: R. Franks n , Z. Liu * & R. Fischer *

author keywords: adaxial; FILAMENTOUS FLOWER; GRAMINIFOLIA; PHABULOSA; STYLOSA; YABBY
MeSH headings : Arabidopsis / growth & development; Arabidopsis / ultrastructure; Arabidopsis Proteins / metabolism; Arabidopsis Proteins / physiology; Body Patterning / physiology; Cell Count; Cell Proliferation; Cell Shape / physiology; Flowers / growth & development; Flowers / ultrastructure; Homeodomain Proteins / metabolism; Mutation; Plant Epidermis / ultrastructure; Transcription Factors / physiology
TL;DR: It is shown that SEUSS and LEUNIG control blade cell number and vasculature development within the petal, and regulate petal polarity along the adaxial/abaxial axis. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2004 journal article

Repression of AGAMOUS by BELLRINGER in floral and inflorescence meristems

PLANT CELL, 16(6), 1478–1489.

By: X. Bao*, R. Franks n , J. Levin & Z. Liu *

Contributors: X. Bao*, R. Franks n , J. Levin & Z. Liu *

MeSH headings : AGAMOUS Protein, Arabidopsis / genetics; Alleles; Amino Acid Sequence; Arabidopsis / genetics; Arabidopsis / metabolism; Arabidopsis Proteins / chemistry; Arabidopsis Proteins / genetics; Arabidopsis Proteins / metabolism; Base Sequence; Flowers / genetics; Flowers / metabolism; Gene Expression Regulation, Plant; Genes, Plant / genetics; Meristem / genetics; Meristem / metabolism; Molecular Sequence Data; Mutation / genetics; Phenotype; Protein Binding; Protein Structure, Tertiary; Repressor Proteins / chemistry; Repressor Proteins / genetics; Repressor Proteins / metabolism
TL;DR: It is shown that the floral phenotype of blr mutants is caused by derepression of AG, suggesting that BLR functions as a transcription repressor, and the findings will facilitate the identification of regulatory targets of other BELL proteins and help determine their biological functions. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
15. Life on Land (OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2002 journal article

SEUSS, a member of a novel family of plant regulatory proteins, represses floral homeotic gene expression with LEUNIG

Development, 129(1), 253–263. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036333380&partnerID=MN8TOARS

By: R. Franks , C. Wang, J. Levin & Z. Liu

Contributors: R. Franks , C. Wang, J. Levin & Z. Liu

www.scopus.com
Source: ORCID
Added: January 22, 2019

2002 journal article

SEUSS, a member of a novel family of plant regulatory proteins, represses floral homeotic gene expression with LEUNIG.

129(1), 253–263. http://europepmc.org/abstract/med/11782418

By: R. Franks , C. Wang, J. Levin, Z. Liu & Development

europepmc.org
Source: ORCID
Added: January 22, 2019

2001 article

Floral Homeotic Gene Regulation

Franks, R. G., & Liu, Z. (2010, June). Horticultural Reviews, pp. 41–77.

By: R. Franks*  & Z. Liu *

Source: ORCID
Added: January 22, 2019

2000 journal article

Regulation of gynoecium marginal tissue formation by LEUNIG and AINTEGUMENTA

Plant Cell, 12(10), 1879–1891.

By: Z. Liu *, R. Franks*  & V. Klink *

Contributors: Z. Liu *, R. Franks*  & V. Klink *

MeSH headings : Arabidopsis / cytology; Arabidopsis / genetics; Arabidopsis / physiology; Arabidopsis Proteins; Homeodomain Proteins / genetics; Homeodomain Proteins / metabolism; Plant Proteins / genetics; Plant Proteins / metabolism; Plant Stems / cytology; Plant Stems / physiology; Plant Stems / ultrastructure; Seeds / physiology; Seeds / ultrastructure; Transcription Factors / genetics; Transcription Factors / metabolism
TL;DR: It is proposed that LEUNIG and AINTEGUMENTA act together to control the expression of common target genes that regulate cell proliferation associated with marginal tissue development in leunig aintegumenta double mutants. (via Semantic Scholar)
Source: ORCID
Added: January 22, 2019

1994 journal article

Control of CNS midline transcription by asymmetric E-box-like elements: similarity to xenobiotic responsive regulation.

120(12), 3563–3569. http://europepmc.org/abstract/med/7821222

By: W. Ka, F. Rg, K. Y, C. St & Development

europepmc.org
Source: ORCID
Added: January 22, 2019

1994 journal article

Controls of CNS midline transcription by asymmetric E-box-like elements: Similarity to xenobiotic responsive regulation

Development, 120(12), 3563–3569. http://www.scopus.com/inward/record.url?eid=2-s2.0-0028172292&partnerID=MN8TOARS

Contributors: K. Wharton Jr., R. Franks , Y. Kasai & S. Crews

www.scopus.com
Source: ORCID
Added: January 22, 2019

1994 journal article

Transcriptional activation domains of the single-minded bHLH protein are required for CNS midline cell development

Mechanisms of Development, 45(3), 269–277.

By: R. Franks*  & S. Crews *

Contributors: R. Franks*  & S. Crews *

author keywords: BASIC-HELIX-LOOP-HELIX; DROSOPHILA; PAS DOMAIN; SINGLE-MINDED; TRANSCRIPTIONAL ACTIVATOR
MeSH headings : Animals; Cells, Cultured; Central Nervous System / cytology; Central Nervous System / embryology; Cloning, Molecular; Drosophila melanogaster; Gene Expression Regulation; Helix-Loop-Helix Motifs / genetics; Nuclear Proteins / genetics; Nuclear Proteins / physiology; Phenotype; Protein Binding; Sp1 Transcription Factor / metabolism; Trans-Activators / genetics; Trans-Activators / physiology; Transformation, Genetic
TL;DR: Germ line transformation experiments indicate that the carboxy terminal activation domains, the PAS dimerization domain, and the putative DNA binding basic domain of Single-minded are required for expression of CNS midline genes in vivo. (via Semantic Scholar)
Source: ORCID
Added: January 22, 2019

1992 journal article

Drosophila single‐minded gene and the molecular genetics of CNS midline development

Journal of Experimental Zoology, 261(3), 234–244.

By: S. Crews *, R. Franks* , S. Hu *, B. Matthews * & J. Nambu*

Contributors: S. Crews *, R. Franks* , S. Hu *, B. Matthews * & J. Nambu*

MeSH headings : Animals; Cell Differentiation / genetics; Central Nervous System / cytology; Central Nervous System / embryology; Drosophila / cytology; Drosophila / embryology; Drosophila / genetics; Genes, Regulator; Mutation; Phenotype; Stem Cells
TL;DR: This work has focused on the development of a small group of neurons and glia that lie along the midline of the Drosophila CNS, and identified a large number of potential genes which exhibit various midline expression patterns and may be involved in discrete aspects of midline cell development. (via Semantic Scholar)
Source: ORCID
Added: January 22, 2019

1990 journal article

The single-minded gene of Drosophila is required for the expression of genes important for the development of CNS midline cells

Cell, 63(1), 63–75.

By: J. Nambu*, R. Franks* , S. Hu * & S. Crews *

Contributors: J. Nambu*, R. Franks* , S. Hu * & S. Crews *

MeSH headings : Animals; Drosophila / embryology; Drosophila / genetics; Embryo, Nonmammalian / physiology; Gene Expression Regulation; Genes; Mutation; Nervous System / cytology; Nervous System / embryology; Phenotype
TL;DR: Evidence is presented that sim is required for midline expression of a group of genes including slit, Toll, rhomboid, engrailed, and a gene at 91F, and that the snail gene is required to repress sim and other midline genes in the presumptive mesoderm. (via Semantic Scholar)
Source: ORCID
Added: January 22, 2019

Employment

Updated: February 19th, 2018 14:47

2004 - present

North Carolina State University Raleigh, NC, US
Professor Plant and Microbial Biology

Education

Updated: November 5th, 2015 08:19

1986 - 1994

University of California Los Angeles Los Angeles, CA, US
Ph.D. Neurosciences

Funding History

Funding history based on the linked ORCID record. Updated: November 25th, 2019 07:46

grant June 1, 2019 - May 31, 2023
Collaborative Research: RoL: Rapid Evolution of Reproductive Isolation via Hybrid Seed Lethality in Mimulus
Directorate for Biological Sciences
grant May 1, 2016 - April 30, 2020
Collaborative Research: Hybrid Seed Inviability and the Evolution of Endosperm Development in Mimulus
Directorate for Biological Sciences
grant March 1, 2016 - February 29, 2020
Sexual Plant Reproduction – Seed formation
European Commission
grant March 1, 2014 - February 28, 2019
Transcriptional Nodes Coordinate Patterning and Cellular Proliferation during Carpel Margin Meristem Development
Directorate for Biological Sciences
grant August 1, 2010 - January 31, 2017
Evolution of Floral Display Strategies in Dogwoods - A Synergistic Approach to Explore the Developmental and Molecular Mechanisms
Directorate for Biological Sciences
grant August 15, 2008 - July 31, 2014
Transcriptional Regulators Link Patterning and Proliferation during Carpel Margin and Ovule Development
National Science Foundation - Directorate for Biological Sciences
grant September 1, 2004 - August 31, 2009
Molecular Specification and Development of the Carpel Margin Meristem
National Science Foundation - Directorate for Biological Sciences
grant April 9, 2000 - January 1, 2002
ENHANCER OF AINTEGUMENTA IN ARABIDOPSIS DEVELOPMENT
National Institute of General Medical Sciences

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