@article{vetter_wadden_teff_khan_carvajal_ritter_moore_chittams_iagnocco_murayama_et al._2015, title={GLP-1 plays a limited role in improved glycemia shortly after Roux-en-Y gastric bypass: A comparison with intensive lifestyle modification}, volume={64}, DOI={10.2337/db14-0558}, abstractNote={Rapid glycemic improvements following Roux-en-Y gastric bypass (RYGB) are frequently attributed to the enhanced GLP-1 response, but causality remains unclear. To determine the role of GLP-1 in improved glucose tolerance after surgery, we compared glucose and hormonal responses to a liquid meal test in 20 obese participants with type 2 diabetes mellitus who underwent RYGB or nonsurgical intensive lifestyle modification (ILM) (n = 10 per group) before and after equivalent short-term weight reduction. The GLP-1 receptor antagonist exendin(9–39)-amide (Ex-9) was administered, in random order and in double-blinded fashion, with saline during two separate visits after equivalent weight loss. Despite the markedly exaggerated GLP-1 response after RYGB, changes in postprandial glucose and insulin responses did not significantly differ between groups, and glucagon secretion was paradoxically augmented after RYGB. Hepatic insulin sensitivity also increased significantly after RYGB. With Ex-9, glucose tolerance deteriorated similarly from the saline condition in both groups, but postprandial insulin release was markedly attenuated after RYGB compared with ILM. GLP-1 exerts important insulinotropic effects after RYGB and ILM, but the enhanced incretin response plays a limited role in improved glycemia shortly after surgery. Instead, enhanced hepatic metabolism, independent of GLP-1 receptor activation, may be more important for early postsurgical glycemic improvements.}, number={2}, journal={Diabetes}, author={Vetter, M. L. and Wadden, T. A. and Teff, K. L. and Khan, Z. F. and Carvajal, R. and Ritter, S. and Moore, R. H. and Chittams, J. L. and Iagnocco, A. and Murayama, K. and et al.}, year={2015}, pages={434–446} } @article{kral_moore_compher_2015, title={Maternal Concern about Child Weight in a Study of Weight-Discordant Siblings}, volume={32}, ISSN={["1525-1446"]}, DOI={10.1111/phn.12119}, abstractNote={Abstract}, number={2}, journal={PUBLIC HEALTH NURSING}, author={Kral, Tanja V. E. and Moore, Renee H. and Compher, Charlene W.}, year={2015}, pages={132–142} } @article{garetz_mitchell_parker_moore_rosen_giordani_muzumdar_paruthi_elden_willging_et al._2015, title={Quality of Life and Obstructive Sleep Apnea Symptoms After Pediatric Adenotonsillectomy}, volume={135}, ISSN={["1098-4275"]}, DOI={10.1542/peds.2014-0620}, abstractNote={ BACKGROUND AND OBJECTIVES: Data from a randomized, controlled study of adenotonsillectomy for obstructive sleep apnea syndrome (OSAS) were used to test the hypothesis that children undergoing surgery had greater quality of life (QoL) and symptom improvement than control subjects. The objectives were to compare changes in validated QoL and symptom measurements among children randomized to undergo adenotonsillectomy or watchful waiting; to determine whether race, weight, or baseline OSAS severity influenced changes in QoL and symptoms; and to evaluate associations between changes in QoL or symptoms and OSAS severity. }, number={2}, journal={PEDIATRICS}, author={Garetz, Susan L. and Mitchell, Ron B. and Parker, Portia D. and Moore, Renee H. and Rosen, Carol L. and Giordani, Bruno and Muzumdar, Hiren and Paruthi, Shalini and Elden, Lisa and Willging, Paul and et al.}, year={2015}, month={Feb}, pages={E477–E486} } @article{mitchell_garetz_moore_rosen_marcus_katz_arens_chervin_paruthi_amin_et al._2015, title={The use of clinical parameters to predict obstructive sleep apnea syndrome severity in children the childhood adenotonsillectomy (CHAT) study randomized clinical trial}, volume={141}, number={2}, journal={Jama Otolaryngology-Head & Neck Surgery}, author={Mitchell, R. B. and Garetz, S. and Moore, R. H. and Rosen, C. L. and Marcus, C. L. and Katz, E. S. and Arens, R. and Chervin, R. D. and Paruthi, S. and Amin, R. and et al.}, year={2015}, pages={130–136} } @article{katz_moore_rosen_mitchell_amin_arens_muzumdar_chervin_marcus_paruthi_et al._2014, title={Growth After Adenotonsillectomy for Obstructive Sleep Apnea: An RCT}, volume={134}, ISSN={["1098-4275"]}, DOI={10.1542/peds.2014-0591}, abstractNote={ BACKGROUND AND OBJECTIVES: Adenotonsillectomy for obstructive sleep apnea syndrome (OSAS) may lead to weight gain, which can have deleterious health effects when leading to obesity. However, previous data have been from nonrandomized uncontrolled studies, limiting inferences. This study examined the anthropometric changes over a 7-month interval in a randomized controlled trial of adenotonsillectomy for OSAS, the Childhood Adenotonsillectomy Trial. }, number={2}, journal={PEDIATRICS}, author={Katz, Eliot S. and Moore, Renee H. and Rosen, Carol L. and Mitchell, Ron B. and Amin, Raouf and Arens, Raanan and Muzumdar, Hiren and Chervin, Ronald D. and Marcus, Carole L. and Paruthi, Shalini and et al.}, year={2014}, month={Aug}, pages={282–289} } @article{kral_remiker_strutz_moore_2014, title={Role of Child Weight Status and the Relative Reinforcing Value of Food in Children's Response to Portion Size Increases}, volume={22}, ISSN={["1930-739X"]}, DOI={10.1002/oby.20757}, abstractNote={ObjectiveFood portion size is an important determinant of intake in children. It remains unknown if children's weight status and relative reinforcing value of food (RRVF) interact with portion size to affect intake.}, number={7}, journal={OBESITY}, author={Kral, Tanja V. E. and Remiker, Adriane M. and Strutz, Erin M. and Moore, Renee H.}, year={2014}, month={Jul}, pages={1716–1722} } @article{marcus_moore_rosen_giordani_garetz_taylor_mitchell_amin_katz_arens_et al._2013, title={A randomized trial of adenotonsillectomy for childhood sleep apnea}, volume={368}, number={25}, journal={New England Journal of Medicine}, author={Marcus, C. L. and Moore, R. H. and Rosen, C. L. and Giordani, B. and Garetz, S. L. and Taylor, G. and Mitchell, R. B. and Amin, R. and Katz, E. S. and Arens, R. and et al.}, year={2013}, pages={2366–2376} } @article{allison_studt_berkowitz_hesson_moore_dubroff_newberg_stunkard_2013, title={An open-label efficacy trial of escitalopram for night eating syndrome}, volume={14}, ISSN={["1873-7358"]}, DOI={10.1016/j.eatbeh.2013.02.001}, abstractNote={Night eating syndrome (NES) has become increasingly recognized as a disorder in need of effective treatments. Selective serotonin reuptake inhibitors have shown efficacy in previous trials, so we sought to expand our understanding of the efficacy of escitalopram in the current trial.Thirty-one adults with NES participated in a 12-week open-label trial of escitalopram. Outcome measures included the Night Eating Symptom Scale (NESS), percent of daily intake after the evening meal (% intake) and number of nocturnal ingestions/week (NI), weight, total awakenings/week, mood, and quality of life. Mixed-effects models were used to assess change over time.Significant reductions were observed from week 0 to week 12 for the NESS (30.2 to 15.2), % intake (46% to 17%), NI (5.8 to 1.2), weight (90.2 to 88.6 kg), awakenings (8.1 to 2.7), and BDI-II (12.1 to 7.7). Outcomes did not differ significantly by gender, age, race, or psychiatric co-morbidity status. Eighteen of 31 completed 12 weeks of treatment.This open-label trial of escitalopram showed significant reductions in symptoms associated with NES. Randomized controlled trials are warranted to test these findings.clinicaltrials.gov identifier: NCT01401595.}, number={2}, journal={EATING BEHAVIORS}, author={Allison, Kelly C. and Studt, Stacia K. and Berkowitz, Robert I. and Hesson, Louise A. and Moore, Renee H. and Dubroff, Jacob G. and Newberg, Andrew and Stunkard, Albert J.}, year={2013}, month={Apr}, pages={199–203} } @article{volger_wadden_sarwer_moore_chittams_diewald_panigrahi_berkowitz_schmitz_vetter_2013, title={Changes in eating, physical activity and related behaviors in a primary care-based weight loss intervention}, volume={37}, journal={International Journal of Obesity}, author={Volger, S. and Wadden, T. A. and Sarwer, D. B. and Moore, R. H. and Chittams, J. and Diewald, L. K. and Panigrahi, E. and Berkowitz, R. I. and Schmitz, K. and Vetter, M. L.}, year={2013}, pages={S12–18} } @article{vetter_wadden_chittams_diewald_panigrahi_volger_sarwer_moore_2013, title={Effect of lifestyle intervention on cardiometabolic risk factors: Results of the POWER-UP trial}, volume={37}, journal={International Journal of Obesity}, author={Vetter, M. L. and Wadden, T. A. and Chittams, J. and Diewald, L. K. and Panigrahi, E. and Volger, S. and Sarwer, D. B. and Moore, R. H.}, year={2013}, pages={S19–24} } @article{vetter_wadden_vinnard_moore_khan_volger_sarwer_faulconbridge_2013, title={Gender differences in the relationship between symptoms of depression and high-sensitivity CRP}, volume={37}, journal={International Journal of Obesity}, author={Vetter, M. L. and Wadden, T. A. and Vinnard, C. and Moore, R. H. and Khan, Z. and Volger, S. and Sarwer, D. B. and Faulconbridge, L. F.}, year={2013}, pages={S38–43} } @article{moore_sarwer_lavenberg_lane_evans_volger_wadden_2013, title={Relationship Between Sexual Function and Quality of Life in Obese Persons Seeking Weight Reduction}, volume={21}, ISSN={["1930-739X"]}, DOI={10.1002/oby.20398}, abstractNote={ObjectiveThis study investigated sexual functioning in persons with obesity and seeking weight loss, and the associations of sexual functioning with relevant demographic and clinical variables as well as quality of life were investigated.}, number={10}, journal={OBESITY}, author={Moore, Renee H. and Sarwer, David B. and Lavenberg, Jeffrey A. and Lane, Ilana B. and Evans, Joanna L. and Volger, Sheri and Wadden, Thomas A.}, year={2013}, month={Oct}, pages={1966–1974} } @article{xanthopoulos_moore_wadden_bishop-gilyard_gehrman_berkowitz_2013, title={The Association Between Weight Loss in Caregivers and Adolescents in a Treatment Trial of Adolescents With Obesity}, volume={38}, ISSN={["1465-735X"]}, DOI={10.1093/jpepsy/jst024}, abstractNote={OBJECTIVE The relationship between weight change in caregivers and their adolescents was evaluated following a randomized trial of lifestyle modification for adolescents, which included either a conventional diet or meal replacements. METHODS Adolescents (N = 113) had an M ± SD age of 15.0 ± 1.3 years (62% African American; 26% Caucasian, 12% other; 81% female) and body mass index of 37.1 ± 5.1 kg/m(2). RESULTS Mixed effects models yielded a significant association between percentage change in body mass index of caregivers and adolescents from baseline to months 4 and 12 (p = .01). When caregivers lost above the median (-1.67%) at month 4, their adolescents achieved a significantly greater loss at month 12 (-9.1 ± 1.3%) compared with adolescents whose caregivers lost less than the median (-4.3 ± 1.3%) (p = .003). CONCLUSION Engaging caregivers in their own weight loss efforts during adolescent weight loss treatment may improve adolescent weight loss.}, number={7}, journal={JOURNAL OF PEDIATRIC PSYCHOLOGY}, author={Xanthopoulos, Melissa S. and Moore, Renee H. and Wadden, Thomas A. and Bishop-Gilyard, Chanelle T. and Gehrman, Christine A. and Berkowitz, Robert I.}, year={2013}, month={Aug}, pages={766–774} } @misc{weber_moore_leonard_zemel_2013, title={The fat mass index: Why its height exponent should be 3 and not 2 Reply}, volume={98}, number={5}, journal={American Journal of Clinical Nutrition}, author={Weber, D. R. and Moore, R. H. and Leonard, M. B. and Zemel, B. S.}, year={2013}, pages={1368–1369} } @article{sarwer_moore_diewald_chittams_berkowitz_vetter_volger_wadden_2013, title={The impact of a primary care-based weight loss intervention on the quality of life}, volume={37}, journal={International Journal of Obesity}, author={Sarwer, D. B. and Moore, R. H. and Diewald, L. K. and Chittams, J. and Berkowitz, R. I. and Vetter, M. and Volger, S. and Wadden, T. A.}, year={2013}, pages={S25–30} }