Works (18)
Updated: July 11th, 2023 21:20
2023 journal article
Spray-Dried Plasma Promotes Broiler Chick Growth by Enhancing Immune Surveillance
ANIMALS, 13(9).
author keywords: spray-dried plasma; growth performance; immunocompetence; bifidobacteria; immunoglobulin; heterophils; broiler chicken
TL;DR:
Dietary SDP at 30 g/kg enhanced immune surveillance by increasing circulating IgY levels, maintaining a normal oxidative state, and increasing gut Bifidobacteria, thereby improving chick growth performance.
(via Semantic Scholar)
www.mdpi.com (publisher PDF)
Source: Web Of Science
Added: May 30, 2023
2020 journal article
Attenuated Salmonella enterica Serovar Typhimurium, Strain NC983, Is Immunogenic, and Protective against Virulent Typhimurium Challenges in Mice
VACCINES, 8(4).
author keywords: Salmonella typhimurium; NC983; vaccine; in vivo; infection; C57BL/6 mice; BALB/c mice; IgG
TL;DR:
Oral delivery of strain NC983 was capable of fully protecting C57BL/6 and BALB/c mice against challenge with virulent Typhimurium, and results indicate that strainNC983 is a potential live attenuated vaccine strain that warrants further development.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: January 19, 2021
2020 article
Connecting the microbiome to host metabolites: understanding how the microbiome controls immune activity in birds
Koci, M., Ballou, A., Wei, X., Zhang, L., Liew, Z., & Ali, R. (2020, April). FASEB JOURNAL, Vol. 34.
TL;DR:
Analysis of the metabolites in serum and digesta from probiotic‐fed animals identified several metabolite changes correlate with the change in ATP levels in lymphocytes and putative changes in pro‐ and anti‐inflammatory cytokine production.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy
(OpenAlex)
Source: Web Of Science
Added: October 12, 2020
2017 journal article
A comparison of sequencing platforms and bioinformatics pipelines for compositional analysis of the gut microbiome
BMC MICROBIOLOGY, 17.
author keywords: 16S rRNA amplicon sequencing; microbiome analysis; microbiome; microbiome composition; next generation sequencing platforms; Bioinformatics pipeline; NGS bias
MeSH headings : Analysis of Variance; Animals; Bacteria / classification; Bacteria / genetics; Base Sequence; Biodiversity; Cecum / microbiology; Chickens / microbiology; Computational Biology / instrumentation; Computational Biology / methods; DNA, Bacterial / analysis; DNA, Bacterial / genetics; DNA, Bacterial / isolation & purification; Gastrointestinal Microbiome / genetics; Gene Library; High-Throughput Nucleotide Sequencing / instrumentation; High-Throughput Nucleotide Sequencing / methods; Microbial Consortia / genetics; Multivariate Analysis; Phylogeny; RNA, Ribosomal, 16S / genetics; Reproducibility of Results; Statistics as Topic
TL;DR:
Overall microbiome compositional profiles were comparable between platforms; however, average relative abundance of specific taxa varied depending on sequencing platform, library preparation method, and bioinformatics analysis.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2017 journal article
An Attenuated Salmonella enterica Serovar Typhimurium Strain and Galacto-Oligosaccharides Accelerate Clearance of Salmonella Infections in Poultry through Modifications to the Gut Microbiome
Applied and Environmental Microbiology, 84(5).
Ed(s): J. Schottel
author keywords: chicken gut microbiome; gut microbiome modulation; prebiotics
MeSH headings : Animals; Bacterial Vaccines / pharmacology; Chickens; Female; Gastrointestinal Microbiome / drug effects; Oligosaccharides / administration & dosage; Poultry Diseases / microbiology; Poultry Diseases / prevention & control; Prebiotics / administration & dosage; Random Allocation; Salmonella Infections, Animal / microbiology; Salmonella Infections, Animal / prevention & control; Salmonella typhimurium / immunology; Vaccines, Attenuated / pharmacology
TL;DR:
It is demonstrated that a manipulation of the chicken gut microbiota by the administration of an attenuated Salmonella strain or prebiotic galacto-oligosaccharides (GOS) can promote resistance to Salmonellosis via increases of beneficial microorganisms that translate into a less hospitable gut microenvironment.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, Crossref, NC State University Libraries
Added: August 6, 2018
2014 journal article
Genetic Variation within the Mx Gene of Commercially Selected Chicken Lines Reveals Multiple Haplotypes, Recombination and a Protein under Selection Pressure
PLoS ONE, 9(9), e108054.
Contributors: J. Fulton *, J. Arango *, n, E. Bohorquez n, A. Lund*, C. Ashwell n , P. Settar*, . N.P. O'Sullivan*, M. Koci n
Ed(s): A. Arez
MeSH headings : Animals; Base Sequence; Chickens / genetics; DNA; Haplotypes; Molecular Sequence Data; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Proteins / genetics; Recombination, Genetic; Selection, Genetic; Untranslated Regions
TL;DR:
Results suggest the conflicting reports in the literature describing the impact of the different SNP on chicken Mx function may be due to the varying context of haplotypes present in the populations studied.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018
2013 journal article
Broiler breeder feeding programs and trace minerals on maternal antibody transfer and broiler humoral immune response1
The Journal of Applied Poultry Research, 22(3), 499–510.
Contributors: E. Oviedo-Rondón n , N. Leandro n, n, M. Koci n , V. Moraes n & J. Brake n
author keywords: immunology; breeder; broiler; feeding program; organic mineral
TL;DR:
It was concluded that breeder feeding programs influenced humoral immune response to NDV vaccine in the broiler progeny, and 30% OTM may increase these responses.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, Crossref, NC State University Libraries
Added: August 6, 2018
2012 journal article
Characterization of turkey inducible nitric oxide synthase and identification of its expression in the intestinal epithelium following astrovirus infection
Comparative Immunology, Microbiology and Infectious Diseases, 35(1), 63–69.
Contributors: R. Meyerhoff n, P. Nighot n, n, A. Blikslager n & M. Koci n
author keywords: Astrovirus; Enterocyte; Turkey; Inducible nitric oxide; Innate immunity
MeSH headings : Amino Acid Sequence; Animals; Astroviridae Infections / enzymology; Astroviridae Infections / veterinary; Astroviridae Infections / virology; Avastrovirus / physiology; Avian Proteins / genetics; Avian Proteins / metabolism; Bird Diseases / enzymology; Bird Diseases / virology; Enterocytes / enzymology; Enterocytes / pathology; Enterocytes / virology; Gene Expression; HEK293 Cells; Humans; Intestinal Mucosa / enzymology; Intestinal Mucosa / pathology; Intestinal Mucosa / virology; Lentivirus / genetics; Molecular Sequence Data; Nitric Oxide / biosynthesis; Nitric Oxide Synthase Type II / genetics; Nitric Oxide Synthase Type II / metabolism; Phylogeny; Recombinant Proteins / genetics; Recombinant Proteins / metabolism; Sequence Alignment; Transfection; Turkeys
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, Crossref, NC State University Libraries
Added: August 6, 2018
2012 journal article
Comprehensive analysis of commercially available mouse antichicken monoclonal antibodies for cross-reactivity with peripheral blood leukocytes from commercial turkeys
POULTRY SCIENCE, 91(2), 383–392.
Contributors: R. Meyerhoff n, n, K. Liu *, G. Huang * & M. Koci*
author keywords: turkey; chicken; lymphocyte; cross-reactivity; cell surface marker
MeSH headings : Amino Acid Sequence; Animals; Antibodies, Monoclonal / immunology; CD8 Antigens / immunology; Chickens / immunology; Gene Expression Regulation; Leukocytes / immunology; Mice; Molecular Sequence Data; Turkeys / blood
TL;DR:
Investigation of a large panel of commercially available monoclonal antibodies specific for chicken leukocyte markers for their ability to specifically recognize the turkey homolog of their respective ligand using 2 different genetic lines of commercial turkeys strengthens understanding of the turkey immune system, its relative level of conservation with the chicken system, and adds to the list of reagents that can be reliably used to assess immune responses incommercial turkeys.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
15. Life on Land
(OpenAlex)
Sources: Web Of Science, ORCID
Added: August 6, 2018
2012 article
Comprehensive analysis of commercially available mouse antichicken monoclonal antibodies for cross-reactivity with peripheral blood leukocytes from commercial turkeys (vol 91, pg 383, 2012)
Meyerhoff, R. R., Ali, R. A., Liu, K., Huang, G.-Q., & Koci, M. D. (2012, April 1). POULTRY SCIENCE, Vol. 91, pp. 1043–1043.
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2012 journal article
Direct fed microbial supplementation repartitions host energy to the immune system
JOURNAL OF ANIMAL SCIENCE, 90(8), 2639–2651.
Contributors: R. Qiu n, J. Croom n, n, A. Ballou n, C. Smith n, C. Ashwell n , H. Hassan n , C. Chiang, M. Koci n
author keywords: broiler; direct fed microbials; energy metabolism; gene expression; probiotics; systemic immune function
MeSH headings : Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Chickens / immunology; Chickens / metabolism; Diet / veterinary; Dietary Supplements; Energy Metabolism / immunology; Enzyme-Linked Immunosorbent Assay; Erythrocytes / immunology; Gene Expression Regulation / immunology; Gram-Positive Bacteria / physiology; Immunoglobulin A / blood; Immunoglobulin G / blood; Male; Oxygen Consumption; Sheep; Time Factors
TL;DR:
Data indicate that supplementation with the direct fed microbial used in this study resulted in energy re-partitioning to the immune system and an increase in antibody production independent of changes in whole body metabolism or growth performance.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy
(OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2011 journal article
Effects of broiler breeder genetic, diet type, and feeding program on maternal antibody transfer and development of lymphoid tissues in chicken progeny
The Journal of Applied Poultry Research, 20(4), 474–484.
Contributors: N. Leandro n, n, M. Koci n , V. Moraes n, R. Malheiros n, M. Wineland n, E. Oviedo-Rondón n
author keywords: breeder; bursa; feeding program; genetics; immunity; maternal antibody; spleen
TL;DR:
It was concluded that breeder feeding programs influence MatAb transfer and half-life, and may also affect the early development of lymphoid tissues.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
Sources: Web Of Science, ORCID, Crossref, NC State University Libraries
Added: August 6, 2018
2011 journal article
Maternal antibody transfer to broiler progeny varies among strains and is affected by grain source and cage density
POULTRY SCIENCE, 90(12), 2730–2739.
Contributors: N. Leandro n, n, M. Koci n , V. Moraes n, P. Eusebio-Balcazar n, J. Jornigan n, R. Malheiros n, M. Wineland n, J. Brake n, E. Oviedo-Rondon n
author keywords: breeder nutrition; broiler progeny; genetic strain; lymphoid tissue
MeSH headings : Animal Feed / analysis; Animal Husbandry; Animal Nutritional Physiological Phenomena; Animals; Antibodies / physiology; Chickens / genetics; Chickens / immunology; Diet / veterinary; Housing, Animal; Immunity, Maternally-Acquired / genetics; Immunity, Maternally-Acquired / physiology; Lymphoid Tissue
TL;DR:
The results of these experiments suggest that breeder strain and cage-density conditions affected MatAb transfer to progeny and embryo development of spleen and bursa.
(via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2010 journal article
Astrovirus infection induces sodium malabsorption and redistributes sodium hydrogen exchanger expression
Virology, 401(2), 146–154.
Contributors: P. Nighot n, A. Moeser n, n, A. Blikslager n & M. Koci n
author keywords: Astrovirus; Viral enteritis; Malabsorption diarrhea; Sodium/hydrogen exchanger; Intestinal electrophysiology; Turkey
MeSH headings : Actins / metabolism; Animals; Astroviridae Infections / pathology; Astroviridae Infections / veterinary; Avastrovirus / pathogenicity; Cell Membrane / chemistry; Cytoplasm / chemistry; Gene Expression; Intestinal Mucosa / pathology; Intestinal Mucosa / ultrastructure; Poultry Diseases / pathology; Poultry Diseases / virology; Sodium / metabolism; Sodium-Hydrogen Exchangers / analysis; Turkeys
TL;DR:
Data suggest astrovirus infection induces sodium malabsorption, possibly through redistribution of specific sodium transporters, which results in the development of an osmotic diarrhoea in infants and the immunocompromised.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, Crossref, NC State University Libraries
Added: August 6, 2018
2003 journal article
The influence of beta-glucan on immune responses in broiler chicks
IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY, 25(3), 461–472.
author keywords: beta-glucan; immune functions; chicken
MeSH headings : Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Animals, Newborn; Antibodies / blood; Antibody Formation / drug effects; Cell Line; Cell Proliferation / drug effects; Chickens; Dietary Supplements; Dose-Response Relationship, Drug; Immunity, Cellular / drug effects; Immunologic Factors / isolation & purification; Immunologic Factors / pharmacology; Interleukin-1 / metabolism; Intestines / drug effects; Intestines / immunology; Leukocytes / drug effects; Leukocytes / immunology; Lymphoid Tissue / drug effects; Lymphoid Tissue / immunology; Macrophages / drug effects; Macrophages / immunology; Nitrites / metabolism; Phagocytosis / drug effects; Proteoglycans; Saccharomyces cerevisiae / chemistry; beta-Glucans / isolation & purification; beta-Glucans / pharmacology
TL;DR:
The findings of these studies imply that β‐glucan can be used as a possible immunomodulator in food animals such as the chicken, because it improves several base‐line immune responses in the chicken.
(via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018
2002 journal article
Interactions of poult enteritis and mortality syndrome-associated reovirus with various cell types in vitro
POULTRY SCIENCE, 81(11), 1661–1667.
author keywords: poult enteritis and mortality syndrome; reovirus; replication; immune response
MeSH headings : Animals; Antigens, Viral / analysis; B-Lymphocytes / metabolism; B-Lymphocytes / virology; Cell Line; Cells, Cultured; Chickens; Cytopathogenic Effect, Viral; Interleukin-1 / genetics; Interleukin-1 / metabolism; Liver / cytology; Liver / virology; Macrophages / metabolism; Macrophages / virology; Microscopy, Electron / veterinary; Orthoreovirus, Avian / growth & development; Orthoreovirus, Avian / immunology; Orthoreovirus, Avian / pathogenicity; Poult Enteritis Mortality Syndrome / metabolism; Poult Enteritis Mortality Syndrome / virology; Poultry Diseases / metabolism; Poultry Diseases / virology; RNA, Messenger / metabolism; Reoviridae Infections / veterinary; Reoviridae Infections / virology; Specific Pathogen-Free Organisms; T-Lymphocytes / metabolism; T-Lymphocytes / virology; Tumor Cells, Cultured; Turkeys; Virus Replication
TL;DR:
It is demonstrated that ARV-CU98 actively infects and replicates in LMH cells, but not in lymphocytes or macrophages, suggesting that the liver may be a target and site of replication of ARV -CU98 in poults experiencing PEMS.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2000 journal article
Alloantigen systems L and P influence phagocytic function independent of the major histocompatability complex (B) in chickens
POULTRY SCIENCE, 79(9), 1271–1275.
author keywords: alloantigen systems; phagocytosis; chicken major histocompatability complex; immunity
MeSH headings : Animals; Cells, Cultured; Chickens / genetics; Chickens / immunology; Crosses, Genetic; Escherichia coli; Female; Genotype; Isoantigens / physiology; Major Histocompatibility Complex; Male; Monocytes / immunology; Phagocytosis
TL;DR:
It is suggested that the L and P non-MHC alloantigen systems have the potential to influence immune responses by modulating phagocytic function in chickens, and this modulation seems to be independent of the B (MHC) system.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
1997 journal article
T-2 tetraol is cytotoxic to a chicken macrophage cell line
POULTRY SCIENCE, 76(2), 311–313.
author keywords: Fusarium; mycotoxin; T-2 tetraol; chicken; macrophage
MeSH headings : Animals; Cell Adhesion / drug effects; Cell Line; Cell Survival / drug effects; Chickens; Dose-Response Relationship, Drug; Macrophages / drug effects; Macrophages / pathology; Macrophages / physiology; T-2 Toxin / analogs & derivatives; T-2 Toxin / toxicity
TL;DR:
It is demonstrated that T-2 tetraol is cytotoxic to chicken macrophage cell line in vitro and the ability of macrophages to adhere to glass surfaces was impaired.
(via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018
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