Richele J. Thompson Milton, M. E., Draughn, G. L., Bobay, B. G., Stowe, S. D., Olson, A. L., Feldmann, E. A., … Cavanagh, J. (2020). The Solution Structures and Interaction of SinR and SinI: Elucidating the Mechanism of Action of the Master Regulator Switch for Biofilm Formation in Bacillus subtilis. JOURNAL OF MOLECULAR BIOLOGY, 432(2), 343–357. https://doi.org/10.1016/j.jmb.2019.08.019 Draughn, G. L., Milton, M. E., Feldmann, E. A., Bobay, B. G., Roth, B. M., Olson, A. L., … Cavanagh, J. (2018). The Structure of the Biofilm-controlling Response Regulator BfmR from Acinetobacter baumannii Reveals Details of Its DNA-binding Mechanism. Journal of Molecular Biology, 430(6), 806–821. https://doi.org/10.1016/j.jmb.2018.02.002 Stowe, S. D., Thompson, R. J., Peng, L., Su, Z., Blackledge, M. S., Draughn, G. L., … Cavanagh, J. (2015). Membrane-Permeabilizing Activity of Reverse-Amide 2-Aminoimidazole Antibiofilm Agents Against Acinetobacter baumannii. CURRENT DRUG DELIVERY, 12(2), 223–230. https://doi.org/10.2174/1567201811666140924125740 Tucker, A. T., Bobay, B. G., Banse, A. V., Olson, A. L., Soderblom, E. J., Moseley, M. A., … Cavanagh, J. (2014). A DNA Mimic: The Structure and Mechanism of Action for the Anti-Repressor Protein AbbA. JOURNAL OF MOLECULAR BIOLOGY, 426(9), 1911–1924. https://doi.org/10.1016/j.jmb.2014.02.010 Olson, A. L., Thompson, R. J., Melander, C., & Cavanagh, J. (2014). Chemical shift assignments and secondary structure prediction of the C-terminal domain of the response regulator BfmR from Acinetobacter baumannii. BIOMOLECULAR NMR ASSIGNMENTS, 8(1), 67–70. https://doi.org/10.1007/s12104-012-9454-2 Bobay, B. G., Thompson, R. J., Milton, D. L., & Cavanagh, J. (2014). Chemical shift assignments and secondary structure prediction of the phosphorelay protein VanU from Vibrio anguillarum. BIOMOLECULAR NMR ASSIGNMENTS, 8(1), 177–179. https://doi.org/10.1007/s12104-013-9478-2 Brackett, C. M., Melander, R. J., An, I. H., Krishnamurthy, A., Thompson, R. J., Cavanagh, J., & Melander, C. (2014). Small-Molecule Suppression of beta-Lactam Resistance in Multidrug-Resistant Gram-Negative Pathogens. JOURNAL OF MEDICINAL CHEMISTRY, 57(17), 7450–7458. https://doi.org/10.1021/jm501050e Olson, A. L., Tucker, A. T., Bobay, B. G., Soderblom, E. J., Moseley, M. A., Thompson, R. J., & Cavanagh, J. (2014). Structure and DNA-Binding Traits of the Transition State Regulator AbrB. STRUCTURE, 22(11), 1650–1656. https://doi.org/10.1016/j.str.2014.08.018 Stowe, S. D., Tucker, A. T., Thompson, R., Piper, A., Richards, J. J., Rogers, S. A., … Cavanagh, J. (2012). Evaluation of the toxicity of 2-aminoimidazole antibiofilm agents using both cellular and model organism systems. DRUG AND CHEMICAL TOXICOLOGY, 35(3), 310–315. https://doi.org/10.3109/01480545.2011.614620 Thompson, R. J., Bobay, B. G., Stowe, S. D., Olson, A. L., Peng, L., Su, Z., … Cavanagh, J. (2012). Identification of BfmR, a Response Regulator Involved in Biofilm Development, as a Target for a 2-Aminoimidazole-Based Antibiofilm Agent. BIOCHEMISTRY, 51(49), 9776–9778. https://doi.org/10.1021/bi3015289 Bobay, B. G., Stewart, A. L., Tucker, A. T., Thompson, R. J., Varney, K. M., & Cavanagh, J. (2012). Structural insights into the calcium-dependent interaction between calbindin-D28K and caspase-3. FEBS LETTERS, 586(20), 3582–3589. https://doi.org/10.1016/j.febslet.2012.08.032 Stowe, S. D., Richards, J. J., Tucker, A. T., Thompson, R., Melander, C., & Cavanagh, J. (2011). [Review of Anti-biofilm compounds derived from marine sponges]. Marine Drugs, 9(10), 2010–2035. Bobay, B. G., Thompson, R. J., Hoch, J. A., & Cavanagh, J. (2010). Long range dynamic effects of point-mutations trap a response regulator in an active conformation. FEBS LETTERS, 584(19), 4203–4207. https://doi.org/10.1016/j.febslet.2010.08.051 Hobbs, C. A., Bobay, B. G., Thompson, R. J., Perego, M., & Cavanagh, J. (2010). NMR Solution Structure and DNA-binding Model of the DNA-binding Domain of Competence Protein A. JOURNAL OF MOLECULAR BIOLOGY, 398(2), 248–263. https://doi.org/10.1016/j.jmb.2010.03.003 Hobbs, C. A., Deterding, L. J., Perera, L., Bobay, B. G., Thompson, R. J., Darden, T. A., … Tomer, K. B. (2009). Structural Characterization of the Conformational Change in Calbindin-D-28k upon Calcium Binding Using Differential Surface Modification Analyzed by Mass Spectrometry. BIOCHEMISTRY, 48(36), 8603–8614. https://doi.org/10.1021/bi900350q Kojetin, D. J., McLaughlin, P. D., Thompson, R. J., Dubnau, D., Prepiak, P., Rance, M., & Cavanagh, J. (2009). Structural and Motional Contributions of the Bacillus subtilis ClpC N-Domain to Adaptor Protein Interactions. JOURNAL OF MOLECULAR BIOLOGY, 387(3), 639–652. https://doi.org/10.1016/j.jmb.2009.01.046 Sullivan, D. M., Bobay, B. G., Kojetin, D. J., Thompson, R. J., Rance, M., Strauch, M. A., & Cavanagh, J. (2008). Insights into the Nature of DNA Binding of AbrB-like Transcription Factors. STRUCTURE, 16(11), 1702–1713. https://doi.org/10.1016/j.str.2008.08.014 Kojetin, D. J., McLaughlin, P. D., Thompson, R. J., Venters, R. A., Rance, M., & Cavanagh, J. (2007). NMR assignment of the N-terminal repeat domain of Bacillus subtilis ClpC. BIOMOLECULAR NMR ASSIGNMENTS, 1(2), 163–165. https://doi.org/10.1007/s12104-007-9046-8 Kordys, D. R., Bobay, B. G., Thompson, R. J., Venters, R. A., & Cavanagh, J. (2007). Peptide binding proclivities of calcium loaded calbindin-D28k. FEBS LETTERS, 581(24), 4778–4782. https://doi.org/10.1016/j.febslet.2007.09.004 McLaughlin, P. D., Bobaya, B. G., Regel, E. J., Thompson, R. J., Hoch, J. A., & Cavanagh, J. (2007). Predominantly buried residues in the response regulator Spo0F influence specific sensor kinase recognition. FEBS LETTERS, 581(7), 1425–1429. https://doi.org/10.1016/j.febslet.2007.02.061 Bobay, B. G., Mueller, G. A., Thompson, R. J., Murzin, A. G., Venters, R. A., Strauch, M. A., & Cavanagh, J. (2006). NMR structure of AbhN and comparison with AbrBN - First insights into the DNA binding promiscuity and specificity of AbrB-like transition state regulator proteins. JOURNAL OF BIOLOGICAL CHEMISTRY, 281(30), 21399–21409. https://doi.org/10.1074/jbc.M601963200 Kojetin, D. J., Venters, R. A., Kordys, D. R., Thompson, R. J., Kumar, R., & Cavanagh, J. (2006). Structure, binding interface and hydrophobic transitions of Ca2+-loaded calbindin-D-28K. Nature Structural & Molecular Biology, 13(7), 641–647. https://doi.org/10.1038/nsmb1112d Kojetin, D. J., Thompson, R. J., Benson, L. M., Naylor, S., Waterman, J., Davies, K. G., … Cavanagh, J. (2005). Structural analysis of divalent metals binding to the Bacillus subtilis response regulator Spo0F: the possibility for In vitro metalloregulation in the initiation of sporulation. BIOMETALS, 18(5), 449–466. https://doi.org/10.1007/s10534-005-4303-8 Bobay, B. G., Benson, L., Naylor, S., Feeney, B., Clark, A. C., Goshe, M. B., … Cavanagh, J. (2004). Evaluation of the DNA Binding Tendencies of the Transition State Regulator AbrB†. Biochemistry, 43(51), 16106–16118. https://doi.org/10.1021/bi048399h Ulrich, D. L., Thompson, R., Bassler, B., Cavanagh, J., & Loria, J. P. (2004). H-1, N-15, and C-13 chemical shift assignments of the Vibrio harveyi histidine phosphotransferase protein LuxU. JOURNAL OF BIOMOLECULAR NMR, 29(4), 551–552. https://doi.org/10.1023/B:JNMR.0000034349.22942.e1 Kojetin, D. J., Thompson, R. J., & Cavanagh, J. (2004, February 27). Sub-classification of response regulators using the surface characteristics of their receiver domains (FEBS 27785) (vol 554, pg 231, 2003). FEBS LETTERS, Vol. 560, pp. 227–228. https://doi.org/10.1016/s0014-5793(04)00063-8 Cavanagh, J., Benson, L. M., Thompson, R., & Naylor, S. (2003). In-line desalting mass spectrometry for the study of noncovalent biological complexes. ANALYTICAL CHEMISTRY, 75(14), 3281–3286. https://doi.org/10.1021/ac030182q Kojetin, D. J., Thompson, R. J., & Cavanagh, J. (2003). Sub-classification of response regulators using the surface characteristics of their receiver domains. FEBS LETTERS, 554(3), 231–236. https://doi.org/10.1016/S0014-5793(03)01167-0 Venters, R. A., Benson, L. M., Craig, T. A., Paul, K. H., Kordys, D. R., Thompson, R., … Cavanagh, J. (2003). The effects of Ca2+ binding on the conformation of calbindin D-28K: A nuclear magnetic resonance and microelectrospray mass spectrometry study. ANALYTICAL BIOCHEMISTRY, 317(1), 59–66. https://doi.org/10.1016/S0003-2697(03)00084-8 Venters, R. A., Thompson, R., & Cavanagh, J. (2002). Current approaches for the study of large proteins by NMR. JOURNAL OF MOLECULAR STRUCTURE, 602, 275–292. https://doi.org/10.1016/s0022-2860(01)00690-1 Benson, L. M., Vaughn, J. L., Strauch, M. A., Bobay, B. G., Thompson, R., Naylor, S., & Cavanagh, J. (2002). Macromolecular assembly of the transition state regulator AbrB in its unbound and complexed states probed by microelectrospray ionization mass spectrometry. ANALYTICAL BIOCHEMISTRY, 306(2), 222–227. https://doi.org/10.1006/abio.2002.5704 Cavanagh, J., Thompson, R., Bobay, B., Benson, L. M., & Naylor, S. (2002). Stoichiometries of protein - Protein/DNA binding and conformational changes for the transition-state regulator AbrB measured by pseudo cell-size exclusion chromatography-mass spectrometry. BIOCHEMISTRY, 41(25), 7859–7865. https://doi.org/10.1021/bi0202225 Sehgal, A. C., Tompson, R., Cavanagh, J., & Kelly, R. M. (2002). Structural and catalytic response to temperature and cosolvents of carboxylesterase EST1 from the extremely thermoacidophilic archaeon Sulfolobus solfataricus P1. BIOTECHNOLOGY AND BIOENGINEERING, 80(7), 784–793. https://doi.org/10.1002/bit.10433