Works (5)

Updated: April 4th, 2024 01:40

2023 review

Asthma: The Use of Animal Models and Their Translational Utility

[Review of ]. CELLS, 12(7).

By: J. Woodrow*, M. Sheats n, B. Cooper n & R. Bayless n

author keywords: asthma; animal model; inflammation
MeSH headings : Humans; Mice; Rats; Animals; Guinea Pigs; Sheep; Horses; Dogs; Disease Models, Animal; Asthma / drug therapy; Proteins; Inflammation
TL;DR: This review aims to discuss the animal models most available for asthma investigation, with an emphasis on describing the inciting antigen/allergen, inflammatory response induced, and its translation to human asthma. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: April 6, 2023

2022 article

Investigation of plasma cell-free DNA as a potential biomarker in horses

Bayless, R. L., Cooper, B. L., & Sheats, M. K. (2022, February 15). JOURNAL OF VETERINARY DIAGNOSTIC INVESTIGATION, Vol. 34.

By: R. Bayless n, B. Cooper n & M. Sheats n

author keywords: biomarker; cell-free DNA; cfDNA; colic; equine; gastrointestinal
MeSH headings : Animals; Biomarkers; Cell-Free Nucleic Acids; Colic / diagnosis; Colic / veterinary; DNA; Horse Diseases / diagnosis; Horses; Humans; Plasma
TL;DR: The results with extracted-plasma samples provide proof of concept for further investigation of plasma cfDNA as a biomarker in horses and accuracy in neat equine plasma using a benchtop fluorometer. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: March 7, 2022

2022 journal article

Withaferin A Inhibits Neutrophil Adhesion, Migration, and Respiratory Burst and Promotes Timely Neutrophil Apoptosis

FRONTIERS IN VETERINARY SCIENCE, 9.

By: R. Bayless n, R. Bayless, M. Sheats n & S. Jones n

Contributors: R. Bayless n, R. Bayless, R. Bayless, R. Bayless, R. Bayless, R. Bayless, R. Bayless

Ed(s): R. Bayless n

author keywords: neutrophil (PMN); Withaferin A (PubChem CID; 265237); equine; inflammation; phytochemical; veterinary medicine; novel therapeutic
TL;DR: The data demonstrate that WFA may reduce neutrophil-mediated inflammation through multiple mechanisms, including suppression of inflammatory responses and promotion of apoptosis, and additional research is needed to elucidate the molecular mechanisms for these effects. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: July 11, 2022

2021 article

Outcomes after cervical vertebral interbody fusion using an interbody fusion device and polyaxial pedicle screw and rod construct in 10 horses (2015-2019)

Pezzanite, L. M., Easley, J. T., Bayless, R., Aldrich, E., Nelson, B. B., Seim, H. B., III, & Nout-Lomas, Y. S. (2021, May 3). EQUINE VETERINARY JOURNAL, Vol. 5.

By: L. Pezzanite*, J. Easley*, R. Bayless n, E. Aldrich*, B. Nelson*, H. Seim*, Y. Nout-Lomas*

Contributors: R. Bayless n

author keywords: cervical compressive myelopathy; cervical vertebral instability; cervical vertebral malformation; complications; equine neurology; equine neurosurgery; horse; ventral stabilisation; Wobbler' s syndrome
TL;DR: This technique resulted in ≥1 grade gait improvement in 6/10 cases operated and 6/8 cases for which ≥1-year follow-up was available, similar to other methods, and may represent a safer alternative to current techniques of ventral interbody fusion with similar outcomes. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: June 10, 2021

2019 journal article

Equine urinary N-acetyl-beta-D-glucosaminidase assay validation and correlation with other markers of kidney injury

JOURNAL OF VETERINARY DIAGNOSTIC INVESTIGATION, 31(5), 688–695.

By: R. Bayless n, A. Moore n, D. Hassel n, B. Byer n, G. Landolt n & Y. Nout-Lomas n

author keywords: acute kidney injury; horses; N-acetyl-beta-D-glucosaminidase; renal; urine
MeSH headings : Acetylglucosaminidase / urine; Acute Kidney Injury / diagnosis; Acute Kidney Injury / urine; Acute Kidney Injury / veterinary; Animals; Biomarkers / urine; Creatinine / blood; Female; Horse Diseases / diagnosis; Horse Diseases / urine; Horses; Humans; Male; Sodium / urine; gamma-Glutamyltransferase / urine
TL;DR: Urine NAG can be measured in horses and shows positive correlation with 2 current renal biomarkers and additional work is needed to establish normal equine reference intervals and characterize the increase of urine NAG index in horses in relation to tubular injury. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 19, 2019

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