Rubia Maysa Martin

Works (4)

Updated: July 5th, 2023 14:46

2022 article

The Cyanotoxin 2,4-DAB Reduces Viability and Causes Behavioral and Molecular Dysfunctions Associated with Neurodegeneration in Larval Zebrafish

Martin, R. M., Bereman, M. S., & Marsden, K. C. (2022, January 14). NEUROTOXICITY RESEARCH, Vol. 40.

By: R. Martin n, M. Bereman n & K. Marsden n 

author keywords: Cyanotoxins; Mixtures; 2,4-DAB; Zebrafish; Behavior; Proteomics
MeSH headings : Amino Acids, Diamino / toxicity; Animals; Cyanobacteria; Cyanobacteria Toxins; Isomerism; Larva; Neurotoxicity Syndromes; Neurotoxins / toxicity; Zebrafish
TL;DR: Together, the data demonstrate that BMAA and its isomers AEG and 2,4-DAB cause neurotoxic effects in vivo, with 2, 4- DAB as the most potent of the three in the zebrafish model. (via Semantic Scholar)
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Sources: Web Of Science, ORCID, NC State University Libraries
Added: January 15, 2022

2020 journal article

BMAA and MCLR Interact to Modulate Behavior and Exacerbate Molecular Changes Related to Neurodegeneration in Larval Zebrafish

TOXICOLOGICAL SCIENCES, 179(2), 251–261.

By: R. Martin n, M. Bereman n & K. Marsden n 

author keywords: cyanotoxins; mixtures; zebrafish; behavior; proteomics
MeSH headings : Amino Acids, Diamino / toxicity; Animals; Cyanobacteria Toxins; Larva; Proteomics; Zebrafish
TL;DR: This study evaluates the neurotoxic effects of a mixture of two co-occurring cyanotoxins, β-methylamino-L-alanine (BMAA) and microcystin leucine and arginine (MCLR), using the larval zebrafish model to reveal that BMAA and MCLR interact in vivo to enhance neurotoxicity. (via Semantic Scholar)
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Sources: Web Of Science, ORCID, NC State University Libraries
Added: December 15, 2020

2019 journal article

Mixture designs to investigate adverse effects upon co-exposure to environmental cyanotoxins

Toxicology, 421, 74–83.

By: R. Martin n, J. Stallrich n  & M. Bereman n

Contributors: R. Martin n, J. Stallrich n  & M. Bereman n

author keywords: Cyanotoxins; Mixture design; Interaction; Environmental exposure; Proteomics
MeSH headings : Animals; Bacterial Toxins / toxicity; Cell Line; Cell Survival / drug effects; Cyanobacteria; Drug Interactions; Mice; No-Observed-Adverse-Effect Level; Proteome / drug effects; Risk Assessment / methods; Toxicity Tests / methods
TL;DR: The results highlight the need to study combinations of cyanotoxins when investigating the link between cyanobacteria and neurodegenerative pathologies and the application of design of experiment (DoE) as an efficient methodology to study mixtures of relevant environmental toxins. (via Semantic Scholar)
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Sources: Web Of Science, Crossref, ORCID, NC State University Libraries
Added: April 20, 2020

2017 journal article

Exposure to BMAA mirrors molecular processes linked to neurodegenerative disease

Proteomics, 17(17-18).

By: J. Beri, T. Nash, R. Martin & M. Bereman

Source: NC State University Libraries
Added: August 6, 2018

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