Works (1)
Updated: July 5th, 2023 15:48
2009 journal article
Morphogenesis of the Primitive Gut Tube Is Generated by Rho/ROCK/Myosin II-Mediated Endoderm Rearrangements
DEVELOPMENTAL DYNAMICS, 238(12), 3111–3125.
author keywords: gut; Xenopus; morphogenesis; endoderm, intercalation; elongation
MeSH headings : Animals; Animals, Genetically Modified; Body Patterning / genetics; Cell Polarity / genetics; Cell Shape / genetics; Embryo, Nonmammalian; Endoderm / cytology; Endoderm / embryology; Endoderm / metabolism; Gastrointestinal Diseases / congenital; Gastrointestinal Diseases / embryology; Gastrointestinal Tract / abnormalities; Gastrointestinal Tract / embryology; Gastrula / embryology; Gastrula / metabolism; Models, Biological; Morphogenesis / genetics; Nonmuscle Myosin Type IIB / genetics; Nonmuscle Myosin Type IIB / metabolism; Nonmuscle Myosin Type IIB / physiology; Signal Transduction / genetics; Xenopus / embryology; Xenopus / genetics; Xenopus / metabolism; rho-Associated Kinases / genetics; rho-Associated Kinases / metabolism; rho-Associated Kinases / physiology; rhoA GTP-Binding Protein / genetics; rhoA GTP-Binding Protein / metabolism; rhoA GTP-Binding Protein / physiology
TL;DR:
The results suggest that the cellular and molecular events driving tissue elongation in the PGT are mechanistically analogous to those that function during gastrulation, but occur within a novel cylindrical geometry to generate an epithelial‐lined tube.
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UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018