Works (4)

Updated: July 5th, 2023 15:37

2023 journal article

Metabolic engineering of the anthocyanin biosynthetic pathway in Artemisia annua and relation to the expression of the artemisinin biosynthetic pathway

PLANTA, 257(3).

By: R. Judd n, Y. Dong n, X. Sun n, Y. Zhu n, M. Li n & D. Xie n

author keywords: Anthocyanin; Artemisinin; Artemisinic acid; Arteannuin b; Artemisia annua; Plant tissue culture
MeSH headings : Artemisia annua / chemistry; Anthocyanins / metabolism; Biosynthetic Pathways; Metabolic Engineering; Reactive Oxygen Species / metabolism; Tandem Mass Spectrometry; Artemisinins / chemistry; Artemisinins / metabolism
TL;DR: The engineering of anthocyanins does not eliminate the biosynthesis of artemisinin in cells and a new hypothesis that enzymes catalyze the formation of art Artemisinin from dihydroartemisinic acid in non-GT cells is proposed. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID
Added: February 24, 2023

2018 journal article

Evaluation of Digital Image Recognition Methods for Mass Spectrometry Imaging Data Analysis

Journal of The American Society for Mass Spectrometry, 29(12), 2467–2470.

By: M. Ekelöf n, K. Garrard n, R. Judd n, E. Rosen*, D. Xie n, A. Kashuba*, D. Muddiman n

author keywords: Mass spectrometry imaging; Image recognition; SSIM
MeSH headings : Algorithms; Animals; Image Processing, Computer-Assisted / methods; Lymph Nodes / chemistry; Lymph Nodes / metabolism; Macaca mulatta; Maraviroc / pharmacokinetics; Mass Spectrometry / methods; Models, Theoretical; Molecular Imaging / methods; Plant Leaves / chemistry; Tissue Distribution
TL;DR: A method for comprehensive, semi-targeted discovery of molecular distributions of interest from mass spectrometry imaging data, using widely available image similarity scoring algorithms to rank images by spatial correlation is presented. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, Crossref, ORCID
Added: December 10, 2018

2018 journal article

Overexpression of Artemisia annua Cinnamyl Alcohol Dehydrogenase Increases Lignin and Coumarin and Reduces Artemisinin and Other Sesquiterpenes


By: D. Ma n, C. Xu*, F. Alejos-Gonzalez n, H. Wang*, J. Yang*, R. Judd n, D. Xie n

author keywords: Artemisia annua; artemisinin; arteannuin B; cinnamyl alcohol dehydrogenases; coumarin; lignin; sesquiterpenes
TL;DR: The cloning of a cinnamyl alcohol dehydrogenase (AaCAD) from an inbred self-pollinating (SP) A. annua cultivar is described to understand the metabolic control of artemisinin biosynthesis in plants for high production. (via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: August 6, 2018

2016 article

Artemisinin biosynthesis in Artemisia annua and metabolic engineering: questions, challenges, and perspectives

Xie, D.-Y., Ma, D.-M., Judd, R., & Jones, A. L. (2016, December). PHYTOCHEMISTRY REVIEWS, Vol. 15, pp. 1093–1114.

By: D. Xie n, D. Ma n, R. Judd n & A. Jones n

author keywords: Artemisia annua; Artemisinin; Genetics; Malaria; Metabolic profiling; Sesquiterpenoid; Terpenoid
TL;DR: This work focuses on reviewing progresses achieved in understanding biosynthetic pathway, genetic breeding, metabolic engineering, and synthetic biology, and discusses multiple fundamental questions and challenges of artemisinin biosynthesis. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Web Of Science, ORCID
Added: August 6, 2018

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