@article{patel_brady_scharf_2020, title={Single-Incision Laparoscopic Deroofing and Omentalization of a Cystic Renal Adenoma in a Dog}, volume={56}, ISSN={["1547-3317"]}, DOI={10.5326/JAAHA-MS-6991}, abstractNote={ABSTRACT
               A 12 yr old 13.5 kg male castrated Pembroke Welsh corgi was presented for evaluation of a suspected renal cyst following multiple episodes of lethargy and abdominal pain. Abdominal imaging revealed a large, thin-walled, hypoechoic cystic lesion associated with the cranial pole of the left kidney and a second smaller cystic lesion on the caudal pole. The larger cystic lesion was repeatedly drained percutaneously, but the lesion returned to initial size and clinical signs returned within weeks. Percutaneous ethanol sclerotherapy achieved only transient improvement in lesion size and abdominal discomfort. Laparoscopic deroofing and omentalization of the larger left renal cystic lesion was performed. The resected cystic wall was histopathologically consistent with a renal adenoma. Abdominal ultrasonography performed 1 mo postoperatively found no recurrence of the cystic renal adenoma. Repeated ultrasonography at 3 mo postoperatively detected a small cystic lesion at the cranial pole of the left kidney, which remained static in appearance at 11 and 18 mo postoperatively. During all follow-up visits, the dog was reported to be doing well with no recurrence of clinical signs. Renal cysts causing clinical signs and renal adenomas are rare in veterinary medicine; laparoscopic deroofing and omentalization provides a minimally invasive treatment approach.}, number={6}, journal={JOURNAL OF THE AMERICAN ANIMAL HOSPITAL ASSOCIATION}, author={Patel, Nikesh J. and Brady, Rachel and Scharf, Valery F.}, year={2020}, pages={331–335} }
 @article{brady_frank-ito_tran_janum_møller_brix_ottesen_mehlsen_olufsen_2018, title={Personalized mathematical model of endotoxin-induced inflammatory responses in young men and associated changes in heart rate variability}, volume={13}, ISSN={0973-5348 1760-6101}, url={http://dx.doi.org/10.1051/mmnp/2018031}, DOI={10.1051/mmnp/2018031}, abstractNote={The objective of this study was to develop a personalized inflammatory model and estimate subject-specific parameters that could be related to changes in heart rate variability (HRV), a measure that can be obtained non-invasively in real time. An inflammatory model was developed and calibrated to measurements of interleukin-6 (IL-6), tumor necrosis factor (TNF-alpha), interleukin-8 (IL-8) and interleukin-10 (IL-10) over 8 hours in 20 subjects administered a low dose of lipopolysaccharide. For this model, we estimated 11 subject-specific parameters for all 20 subjects. Estimated parameters were correlated with changes in HRV, computed from ECG measurements using a built-in HRV module available in Labchart. Results revealed that patients could be separated into two groups expressing normal and abnormal responses to endotoxin. Abnormal responders exhibited increased HRV, most likely as a result of increased vagal firing. The observed correlation between the inflammatory response and HRV brings us a step further towards understanding if HRV predictions can be used as a marker for inflammation. Analyzing HRV parameters provides an easy, non-invasively obtained measure that can be used to assess the state of the subject, potentially translating to identifying a non-invasive marker that can be used to detect the onset of sepsis.}, number={5}, journal={Mathematical Modelling of Natural Phenomena}, publisher={EDP Sciences}, author={Brady, R. and Frank-Ito, D.O. and Tran, H.T. and Janum, S. and Møller, K. and Brix, S. and Ottesen, J.T. and Mehlsen, J. and Olufsen, M.S.}, editor={Maruta, K. and Minaev, S. and Il Kim, N. and Im, H. and Gubernov, V.Editors}, year={2018}, pages={42} }