2013 journal article

Avidity-mediated virus separation using a hyperthermophilic affinity ligand

BIOTECHNOLOGY PROGRESS, 29(1), 237–246.

By: M. Hussain n, D. Lockney n, R. Wang n, N. Gera n & B. Rao n

author keywords: avidity; affinity ligand; hyperthermophilic; multivalent
MeSH headings : Archaeal Proteins / chemistry; Archaeal Proteins / isolation & purification; Archaeal Proteins / metabolism; DNA-Binding Proteins / chemistry; DNA-Binding Proteins / isolation & purification; DNA-Binding Proteins / metabolism; Ligands; Molecular Weight; Plant Extracts; Plant Leaves / virology; Sulfolobus solfataricus / chemistry; Sulfolobus solfataricus / metabolism; Tobacco / virology; Tombusviridae / isolation & purification
TL;DR: The approach may be broadly relevant to cases where capture of large multivalent species from complex mixtures and subsequent release without the use of harsh elution conditions is necessary, and bypasses chemical conjugation of the affinity ligand to the capture surface. (via Semantic Scholar)
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Added: August 6, 2018

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