Works (12)

Updated: July 5th, 2023 21:21

2012 journal article

Foliar-Applied Small Molecule that Suppresses Biofilm Formation and Enhances Control of Copper-Resistant Xanthomonas euvesicatoria on Pepper

PLANT DISEASE, 96(11), 1638–1644.

By: R. Worthington, S. Rogers*, R. Huigens*, C. Melander* & D. Ritchie n

co-author countries: United States of America πŸ‡ΊπŸ‡Έ
Source: Web Of Science
Added: August 6, 2018

2011 journal article

Synthesis and biological activity of 2-aminoimidazole triazoles accessed by Suzuki-Miyaura cross-coupling

ORGANIC & BIOMOLECULAR CHEMISTRY, 9(8), 3041–3049.

By: S. Reyes n, R. Huigens n, Z. Su n, M. Simon n & C. Melander  n

co-author countries: United States of America πŸ‡ΊπŸ‡Έ
MeSH headings : Acinetobacter baumannii / drug effects; Acinetobacter baumannii / physiology; Biofilms; Imidazoles / chemistry; Methicillin-Resistant Staphylococcus aureus / drug effects; Methicillin-Resistant Staphylococcus aureus / physiology; Molecular Structure; Triazoles / chemical synthesis; Triazoles / pharmacology
Source: Web Of Science
Added: August 6, 2018

2010 journal article

Modulating the development of E. coli biofilms with 2-aminoimidazoles

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 20(21), 6310–6312.

By: C. Reed n, R. Huigens n, S. Rogers n & C. Melander n

co-author countries: United States of America πŸ‡ΊπŸ‡Έ
author keywords: 2-Aminoimidazoles; E. coli; Biofilms
MeSH headings : Acinetobacter baumannii / drug effects; Acinetobacter baumannii / growth & development; Anti-Bacterial Agents / chemical synthesis; Anti-Bacterial Agents / pharmacology; Biofilms / drug effects; Drug Design; Escherichia coli / drug effects; Escherichia coli / growth & development; Hemolysis / drug effects; Humans; Imidazoles / chemical synthesis; Imidazoles / pharmacology; In Vitro Techniques; Structure-Activity Relationship
Source: Web Of Science
Added: August 6, 2018

2010 journal article

Synergistic Effects between Conventional Antibiotics and 2-Aminoimidazole-Derived Antibiofilm Agents

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 54(5), 2112–2118.

By: S. Rogers n, R. Huigens n, J. Cavanagh n & C. Melander n

co-author countries: United States of America πŸ‡ΊπŸ‡Έ
MeSH headings : Acinetobacter baumannii / drug effects; Anti-Bacterial Agents / pharmacology; Bacteria / drug effects; Biofilms / drug effects; Calcium Chloride / pharmacology; Chlorides / pharmacology; Colistin / pharmacology; Drug Resistance, Bacterial; Drug Resistance, Multiple; Drug Synergism; Enterococcus faecium / drug effects; Erythrocytes / drug effects; Escherichia coli / drug effects; Humans; Imidazoles / chemistry; Imidazoles / pharmacology; Magnesium / pharmacology; Manganese Compounds / pharmacology; Methicillin-Resistant Staphylococcus aureus / drug effects; Novobiocin / pharmacology; Staphylococcus epidermidis / drug effects; Tobramycin / pharmacology; Triazoles / pharmacology
Source: Web Of Science
Added: August 6, 2018

2010 journal article

The chemical synthesis and antibiotic activity of a diverse library of 2-aminobenzimidazole small molecules against MRSA and multidrug-resistant A. baumannii

BIOORGANIC & MEDICINAL CHEMISTRY, 18(2), 663–674.

By: R. Huigens n, S. Reyes n, C. Reed n, C. Bunders n, S. Rogers n, A. Steinhauer n, C. Melander n

co-author countries: United States of America πŸ‡ΊπŸ‡Έ
author keywords: 2-Aminobenzimidazole; Chemical library synthesis; Antibiotic; Multidrug-resistant bacteria; Staphylococcus aureus; Acinetobacter baumannii
MeSH headings : Acinetobacter baumannii / drug effects; Anti-Bacterial Agents / chemical synthesis; Anti-Bacterial Agents / chemistry; Anti-Bacterial Agents / pharmacology; Benzimidazoles / chemical synthesis; Benzimidazoles / chemistry; Benzimidazoles / pharmacology; Drug Resistance, Multiple, Bacterial; Methicillin-Resistant Staphylococcus aureus / drug effects; Microbial Sensitivity Tests; Molecular Conformation; Small Molecule Libraries; Stereoisomerism; Structure-Activity Relationship
Source: Web Of Science
Added: August 6, 2018

2009 journal article

A 2-Aminobenzimidazole That Inhibits and Disperses Gram-Positive Biofilms through a Zinc-Dependent Mechanism

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 131(29), 9868-+.

By: S. Rogers n, R. Huigens n & C. Melander n

co-author countries: United States of America πŸ‡ΊπŸ‡Έ
MeSH headings : Benzimidazoles / chemical synthesis; Benzimidazoles / chemistry; Benzimidazoles / pharmacology; Biofilms / drug effects; Biofilms / growth & development; Dose-Response Relationship, Drug; Gram-Positive Bacteria / drug effects; Magnetic Resonance Spectroscopy; Molecular Structure; Structure-Activity Relationship; Zinc / chemistry; Zinc / pharmacology
Source: Web Of Science
Added: August 6, 2018

2009 journal article

Evaluation of dihydrooroidin as an antifouling additive in marine paint

INTERNATIONAL BIODETERIORATION & BIODEGRADATION, 63(4), 529–532.

By: C. Melander n, P. Moeller*, T. Ballard n, J. Richards n, R. Huigens n & J. Cavanagh n

co-author countries: United States of America πŸ‡ΊπŸ‡Έ
author keywords: Antifouling; Biofilms; Natural products
Source: Web Of Science
Added: August 6, 2018

2009 journal article

Inhibition of Acinetobacter baumannii, Staphylococcus aureus and Pseudomonas aeruginosa biofilm formation with a class of TAGE-triazole conjugates

ORGANIC & BIOMOLECULAR CHEMISTRY, 7(4), 794–802.

By: R. Huigens n, S. Rogers n, A. Steinhauer n & C. Melander n

co-author countries: United States of America πŸ‡ΊπŸ‡Έ
MeSH headings : Acinetobacter baumannii / drug effects; Anti-Bacterial Agents / chemical synthesis; Biofilms / drug effects; Imidazoles / chemistry; Pseudomonas aeruginosa / drug effects; Small Molecule Libraries / chemical synthesis; Staphylococcus aureus / drug effects; Triazoles / chemical synthesis
Source: Web Of Science
Added: August 6, 2018

2008 journal article

Control of bacterial biofilms with marine alkaloid derivatives

MOLECULAR BIOSYSTEMS, 4(6), 614–621.

By: R. Huigens n, L. Ma *, C. Gambino n, P. Moeller*, A. Basso n, J. Cavanagh n, D. Wozniak *, C. Melander n

co-author countries: United States of America πŸ‡ΊπŸ‡Έ
MeSH headings : Acinetobacter baumannii / drug effects; Acylation; Alkaloids / chemical synthesis; Alkaloids / chemistry; Alkaloids / pharmacology; Animals; Anti-Bacterial Agents / chemical synthesis; Anti-Bacterial Agents / chemistry; Anti-Bacterial Agents / pharmacology; Biofilms / drug effects; Biofilms / growth & development; Bordetella bronchiseptica / drug effects; Cell Line; Dose-Response Relationship, Drug; Imidazoles / chemical synthesis; Imidazoles / chemistry; Imidazoles / pharmacology; Mice; Microbial Sensitivity Tests; Molecular Structure; Pseudomonas aeruginosa / drug effects; Rats; Staphylococcus aureus / drug effects
Source: Web Of Science
Added: August 6, 2018

2008 journal article

Inhibition and dispersion of proteobacterial biofilms

Chemical Communications (Cambridge, England), (14), 1698–1700.

Source: NC State University Libraries
Added: August 6, 2018

2008 journal article

Synthesis and screening of an oroidin library against Pseudomonas aeruginosa biofilms

CHEMBIOCHEM, 9(8), 1267–1279.

By: J. Richards n, T. Ballard n, R. Huigens n & C. Melander n

co-author countries: United States of America πŸ‡ΊπŸ‡Έ
author keywords: biological activity; drug design; medicinal chemistry; natural products; structure-activity relationships
MeSH headings : Biofilms; Cross-Linking Reagents / chemistry; Databases, Factual; Drug Design; Drug Evaluation, Preclinical; Molecular Structure; Pseudomonas aeruginosa / drug effects; Pyrroles / chemical synthesis; Pyrroles / chemistry; Pyrroles / pharmacology; Structure-Activity Relationship
Source: Web Of Science
Added: August 6, 2018

2007 journal article

Inhibition of Pseudomonas aeruginosa biofilm formation with bromoageliferin analogues

Journal of the American Chemical Society, 129(22), 6966-.

By: R. Huigens, J. Richards, G. Parise, T. Ballard, W. Zeng, R. Deora, C. Melander

Source: NC State University Libraries
Added: August 6, 2018