@article{cerreta_cannizzo_smith_minter_2020, title={Venous hematology, biochemistry, and blood gas analysis of free-ranging Eastern Copperheads (Agkistrodon contortrix) and Eastern Ratsnakes (Pantherophis alleghaniensis)}, volume={15}, ISSN={["1932-6203"]}, DOI={10.1371/journal.pone.0229102}, abstractNote={Hematology, plasma biochemistry, and blood gas analysis were performed on venous samples obtained from free-ranging Eastern Copperheads (Agkistrodon contortrix) and Eastern Ratsnakes (Pantherophis alleghaniensis) in central North Carolina during a mark-recapture study conducted from April to October 2015 at the North Carolina Zoo. Blood samples were collected from 31 (15 male and 16 female) free-ranging copperheads and 34 (20 male and 14 female) free-ranging ratsnakes at the beginning and end of restraint. Restraint was performed for morphometric measurements, sex determination, and identification via placement of intracelomic passive integrated transponder (PIT) tags and marking of ventral scutes with a handheld electrocautery unit. Blood gas analytes were measured at the beginning of restraint and compared to analytes measured at the end to evaluate for changes secondary to handling. Total restraint time prior to the first blood sampling was 1.4 ± 0.4 mins (mean ± SD) and 1.0 ± 0.2 mins (mean ± SD) and restraint time prior to second blood sampling was 12.5 ± 2.4 mins (mean ± SD) and 13.5 ± 3.4 mins (mean ± SD) for copperheads and ratsnakes, respectively. Blood lactate concentrations at the beginning of restraint were similar for both species. Lactate concentrations increased significantly and pH decreased significantly for both species at the end of restraint when compared to the beginning of restraint. Furthermore, lactate concentrations at the end of restraint were significantly elevated in ratsnakes compared to copperheads. This study provides guidelines for interpretation of venous hematology, plasma biochemistry, and blood gas values for free-ranging copperheads and ratsnakes in central North Carolina and demonstrates the physiological response to venous blood gas analytes secondary to capture and restraint.}, number={2}, journal={PLOS ONE}, author={Cerreta, Anthony J. and Cannizzo, Sarah A. and Smith, Dustin C. and Minter, Larry J.}, year={2020}, month={Feb} } @article{cannizzo_lewbart_westermeyer_2017, title={Intraocular pressure in American Bullfrogs (Rana catesbeiana) measured with rebound and applanation tonometry}, volume={20}, ISSN={["1463-5224"]}, url={https://doi.org/10.1111/vop.12463}, DOI={10.1111/vop.12463}, abstractNote={Abstract}, number={6}, journal={VETERINARY OPHTHALMOLOGY}, author={Cannizzo, Sarah A. and Lewbart, Gregory A. and Westermeyer, Hans D.}, year={2017}, month={Nov}, pages={526–532} } @article{cannizzo_rick_harrison_harms_2017, title={PARATHYROID HORMONE, IONIZED CALCIUM, AND 25-HYDROXYVITAMIN D CONCENTRATIONS IN THE DOMESTIC FERRET (MUSTELA PUTORIUS FURO)}, volume={26}, ISSN={["1931-6283"]}, DOI={10.1053/j.jepm.2017.07.004}, abstractNote={Abstract The objective of this study was to measure parathyroid hormone (PTH), ionized calcium, and 25‐hydroxyvitamin D concentrations in healthy intact adult ferrets. Serum was collected from 16 clinically healthy adult ferrets (8 males and 8 females). Concentrations of PTH and 25‐hydroxyvitamin D were measured via commercially available radioimmunoassays validated for humans, dogs, and cats (PTH) plus horses (25‐hydroxyvitamin D). Concentrations of ionized calcium (at pH 7.4) were measured using an ion‐specific electrode. Median (minimum, maximum) concentrations were as follows: PTH 8.7 (2.2, 24.4) pmol/L, ionized calcium 1.15 (1.09, 1.25) mmol/L, and 25‐hydroxyvitamin D 94 (61, 138) nmol/L). Female ferrets had significantly higher concentrations of PTH than male ferrets (female median: 17.1 pmol/L; male median: 6.9 pmol/L). Associations among PTH, ionized calcium, 25‐hydroxyvitamin D, calcium, phosphorus, magnesium, and weight were evaluated. There was a weak negative correlation between PTH concentration and total calcium concentration in female ferrets. As none of these assays have been validated for use in ferrets, results may provide a baseline for clinicians evaluating ferrets for disorders of calcium homeostasis, parathyroid glands, and paraneoplastic syndromes.}, number={4}, journal={JOURNAL OF EXOTIC PET MEDICINE}, author={Cannizzo, Sarah A. and Rick, Markus and Harrison, Tara M. and Harms, Craig A.}, year={2017}, month={Oct}, pages={294–299} } @article{cannizzo_stinner_kennedy-stoskopf_2017, title={PREVALENCE OF CYSTINURIA IN SERVALS (LEPTAILURUS SERVAL) IN THE UNITED STATES}, volume={48}, ISSN={["1937-2825"]}, DOI={10.1638/2016-0177.1}, abstractNote={Abstract Cystinuria is a condition caused by defects in amino acid transport within the kidneys and small intestines. It has been reported in humans, dogs, domestic cats, ferrets, nondomestic canids, and nondomestic felids, including servals (Leptailurus serval). Genetic mutations have been identified in dogs, humans, and domestic cats. Cystinuria usually follows an autosomal recessive inheritance, although it can be autosomal dominant and sex linked. The primary objective of this study was to screen urine samples dried on filter paper from captive servals in the United States for cystinuria by using the cyanide-nitroprusside screening test. A second objective was to determine whether cystinuria is inheritable in servals. Servals were initially recruited for the study by survey. Owners and institutions interested in participating were sent a second survey and filter paper for collecting urine samples. Samples were collected from 25 servals. One additional serval with confirmed cystine urolithiasis was added for a total sample size of 26 servals. Twenty-seven percent (7/26) were positive, 54% (14/26) were weakly positive, and 19% (5/26) were negative. Sex, reproductive status, and urine collection method had no significant association with test results. This condition is likely underreported in servals and should be ruled out in any serval with nonspecific signs of illness; neurologic signs such as lethargy, ataxia, or seizures; ptyalism; or signs of lower urinary tract disease such as dysuria, hematuria, stranguria, pollakiuria, or urethral obstructions.}, number={4}, journal={JOURNAL OF ZOO AND WILDLIFE MEDICINE}, author={Cannizzo, Sarah A. and Stinner, Mindy and Kennedy-Stoskopf, Suzanne}, year={2017}, month={Dec}, pages={1102–1107} }