@article{meichner_olsson_stewart_musser_grindem_2015, title={What is your diagnosis? Urine crystals in a dog}, volume={44}, ISSN={["1939-165X"]}, DOI={10.1111/vcp.12296}, abstractNote={A 24.1 kg, 1.5-year-old intact male Labrador Retriever was presented to the North Carolina State University Veterinary Hospital (NC State VH) Emergency Service for a 3-day history of vomiting, hematochezia, fever, and generalized lymphadenopathy. The referring veterinarian treated the dog with a single dose of enrofloxacin 130 mg IV and discharged him with oral minocycline 10 mg/kg once daily. The dog vomited all oral medications. At NC State VH, CBC abnormalities included mild normocytic anemia (HCT 30.6%, reference interval [RI] 37– 55%;MCV 69.9 fL, RI 60–72 fL) with mildly elevated MCHC (39.8 g/dL, RI 34–38 g/dL), marked leukocytosis (180,900/ lL, RI 4390–11,610/lL), characterized bymarkedmonocytosis (103,113/lL, RI 75–840/lL), moderate neutrophilia (25,326/lL, RI 2840–9112/lL), marked left shift (12,663 band neutrophils), marked increase in intermediateand late-stage myelomonocytic precursors (25,326/lL), moderate lymphocytosis (14,472/lL, RI 594–3305/lL), and thrombocytopenia (52,000/lL, RI 200,000–500,000/lL). In the absence of hemolysis, gross lipemia, and Heinz bodies, MCHC was considered falsely increased due to extreme leukocytosis. Results of a biochemical panel including urea (17 mg/ dL, RI 7–25) and creatinine (1.0 mg/dL, RI 0.3–1.4) were within normal limits. Voided urinalysis included a sediment examination (Figure 1). Acute leukemia was diagnosed and the dog was euthanized. Based on clinical signs, cytology of peripheral lymph node aspirates, microscopic blood smear review, peripheral blood flow cytometry, and necropsy, final diagnosis was acute monocytic (AML-M5) or acute myelomonocytic (AML-M4) leukemia.}, number={4}, journal={VETERINARY CLINICAL PATHOLOGY}, author={Meichner, Kristina and Olsson, Sandra A. and Stewart, Danielle R. and Musser, Margaret L. and Grindem, Carol B.}, year={2015}, month={Dec}, pages={613–614} }