Works (4)

Updated: July 5th, 2023 15:51

2012 journal article

Thermal dose fractionation affects tumour physiological response


By: D. Thrall n, P. Maccarini*, P. Stauffer*, J. Macfall*, M. Hauck n, S. Snyder n, B. Case n, K. Linder n ...

author keywords: thermal dosimetry; tumor oxygenation; microenvironment
MeSH headings : Animals; Antigens, Neoplasm / metabolism; Carbonic Anhydrases / metabolism; Caspase 3 / metabolism; Dogs; Hyperthermia, Induced; Hypoxia-Inducible Factor 1, alpha Subunit / metabolism; Sarcoma / metabolism; Sarcoma / pathology; Sarcoma / therapy; Soft Tissue Neoplasms / metabolism; Soft Tissue Neoplasms / pathology; Soft Tissue Neoplasms / therapy; Tumor Burden; Vascular Endothelial Growth Factor A / metabolism
TL;DR: There was a greater reduction in tumour volume and water diffusion at the end of therapy in tumours receiving one hyperthermia fraction per week, and response data pointed to a one per week prescription being superior. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2011 journal article

Comparison of Genomics and Functional Imaging from Canine Sarcomas Treated with Thermoradiotherapy Predicts Therapeutic Response and Identifies Combination Therapeutics


By: J. Chi n, D. Thrall n, C. Jiang n, S. Snyder n, D. Fels n, C. Landon n, L. McCall n, L. Lan n ...

MeSH headings : Animals; Cluster Analysis; Combined Modality Therapy; Dogs; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Genomics / methods; Humans; Hyperthermia, Induced; Magnetic Resonance Imaging / methods; Oligonucleotide Array Sequence Analysis; Radiotherapy / methods; Reverse Transcriptase Polymerase Chain Reaction; Sarcoma / genetics; Sarcoma / therapy
TL;DR: This is one of the first successful attempts to link changes in gene expression and functional imaging to understand the response heterogeneity and identify compounds enhancing thermoradiotherapy. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2010 journal article

Effect of Oligonucleotide Length on the Assembly of DNA Materials: Molecular Dynamics Simulations of Layer-by-Layer DNA Films

LANGMUIR, 26(22), 17339–17347.

By: A. Singh n, S. Snyder n, L. Lee*, A. Johnston*, F. Caruso* & Y. Yingling n

Contributors: Y. Yingling n, F. Caruso*, A. Johnston*, L. Lee*, S. Snyder n & A. Singh n

MeSH headings : Base Sequence; DNA / chemistry; DNA / genetics; Gold / chemistry; Metal Nanoparticles / chemistry; Molecular Dynamics Simulation; Nanotechnology / methods; Nucleic Acid Conformation; Nucleic Acid Hybridization; Oligodeoxyribonucleotides / chemistry; Oligodeoxyribonucleotides / genetics; Poly T / chemistry; Quartz Crystal Microbalance Techniques
TL;DR: This study suggests that restrainedpolyT, compared to labile suspensions of free polyT, are more capable of hybridization and hence DNA-based assembly, and this can be associated with the limited accessibility of the bases on the surface due to formation of self-protected interactions that prevent efficient hybridization. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2008 journal article

The role of hypoxia in canine cancer


By: S. Snyder n, M. Dewhirst* & M. Hauck n

author keywords: canine; hypoxia; resistance; tumour
MeSH headings : Animals; Cell Hypoxia / physiology; Dog Diseases / metabolism; Dogs; Fluorocarbons / metabolism; Hydrocarbons, Brominated; Neoplasms / metabolism; Neoplasms / veterinary
TL;DR: The knowledge from the human literature of problematic nature of hypoxic tumours combined with the rapid growth of veterinary oncology has necessitated a better understanding of hypoxia in canine tumours. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

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