Sarah E. Culver

Works (5)

Updated: July 5th, 2023 15:45

2018 journal article

Multiloculated solitary (unicameral) bone cyst in a young dog

Veterinary Clinical Pathology, 47(3), 484–488.

By: S. Roode n, H. Shive n, W. Hoorntje n, J. Bernard*, D. Stowe n , R. Pool*, C. Grindem n

author keywords: Canine; cytology; lytic; osseous; osteoclast; skeletal
MeSH headings : Animals; Bone Cysts / complications; Bone Cysts / diagnostic imaging; Bone Cysts / pathology; Bone Cysts / veterinary; Dog Diseases / diagnostic imaging; Dog Diseases / pathology; Dogs; Female; Femur / diagnostic imaging; Femur / pathology; Lameness, Animal / etiology; Lameness, Animal / pathology; Radiography / veterinary
TL;DR: A 20-month-old female spayed Staffordshire Terrier presented to the Orthopedic Surgery Service at North Carolina State University Veterinary Teaching Hospital for evaluation of a 6-week history of toe-touching to nonweight-bearing lameness, and amputation of the right hind limb was performed. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, Crossref, NC State University Libraries
Added: October 16, 2018

2016 journal article

Comprehensive genomic characterization of five canine lymphoid tumor cell lines

BMC Veterinary Research, 12.

By: S. Roode, D. Rotroff, K. Richards, P. Moore, A. Motsinger-Reif, Y. Okamura, T. Mizuno, H. Tsujimoto, S. Suter, M. Breen

Source: NC State University Libraries
Added: August 6, 2018

2013 journal article

Molecular characterization of canine BCR-ABL-positive chronic myelomonocytic leukemia before and after chemotherapy

Veterinary Clinical Pathology, 42(3), 314–322.

By: S. Culver n, D. Ito *, L. Borst n , J. Bell, J. Modiano * & M. Breen n

author keywords: Chromosome; cytogenetics; hematopoietic cells; remission; vincristine
MeSH headings : Animals; Chromosomes, Human, Pair 7 / genetics; Comparative Genomic Hybridization / veterinary; Dog Diseases / drug therapy; Dog Diseases / genetics; Dog Diseases / pathology; Dogs; Fusion Proteins, bcr-abl / genetics; Humans; In Situ Hybridization, Fluorescence / veterinary; Leukemia, Myelomonocytic, Chronic / drug therapy; Leukemia, Myelomonocytic, Chronic / genetics; Leukemia, Myelomonocytic, Chronic / pathology; Leukemia, Myelomonocytic, Chronic / veterinary; Male; Trisomy / genetics
TL;DR: Cytology and flow cytometric techniques were used to diagnose chronic myelomonocytic leukemia in a dog and the applicability of cytogenetics techniques to evaluate the cytogenetic response of canine leukemia to chemotherapy was demonstrated. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, Crossref, NC State University Libraries
Added: August 6, 2018

2013 journal article

Partial cytogenetic response with toceranib and prednisone treatment in a young dog with chronic monocytic leukemia

ANTI-CANCER DRUGS, 24(10), 1098–1103.

By: M. Perez, S. Culver*, J. Owen*, M. Dunbar*, K. Kow, M. Breen n, R. Milner *

author keywords: cytogenetic analysis; fluorescence in-situ hybridization; monocytosis; toceranib; tyrosine kinase inhibitor
MeSH headings : Animals; Antineoplastic Combined Chemotherapy Protocols / administration & dosage; Antineoplastic Combined Chemotherapy Protocols / therapeutic use; Cell Proliferation / drug effects; Dog Diseases / drug therapy; Dog Diseases / genetics; Dogs; Female; Fusion Proteins, bcr-abl / antagonists & inhibitors; Fusion Proteins, bcr-abl / genetics; In Situ Hybridization, Fluorescence; Indoles / administration & dosage; Indoles / therapeutic use; Leukemia, Myeloid / drug therapy; Leukemia, Myeloid / genetics; Leukemia, Myeloid / pathology; Leukemia, Myeloid / veterinary; Prednisone / administration & dosage; Prednisone / therapeutic use; Pyrroles / administration & dosage; Pyrroles / therapeutic use; Translocation, Genetic; Treatment Outcome
TL;DR: A case of CMoL in a young dog that achieved clinical remission with treatment with the tyrosine kinase inhibitor toceranib and prednisone is reported. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2012 journal article

Acute myeloblastic leukemia with associated BCR-ABL translocation in a dog

VETERINARY CLINICAL PATHOLOGY, 41(3), 362–368.

By: J. Figueiredo*, S. Culver n, E. Behling-Kelly *, M. Breen n & K. Friedrichs*

author keywords: Cytogenetics; FISH; immunophenotyping; Raleigh chromosome
MeSH headings : Animals; Bone Marrow / pathology; Cytogenetic Analysis / veterinary; Dog Diseases / genetics; Dog Diseases / immunology; Dog Diseases / pathology; Dogs; Fusion Proteins, bcr-abl / genetics; Hematologic Tests / veterinary; Immunophenotyping / veterinary; In Situ Hybridization, Fluorescence / veterinary; Leukemia, Myeloid, Acute / genetics; Leukemia, Myeloid, Acute / immunology; Leukemia, Myeloid, Acute / pathology; Leukemia, Myeloid, Acute / veterinary; Male; Translocation, Genetic / genetics
TL;DR: This is the first report of AML with a BCR-ABL translocation in a domestic animal and large multinucleated cells were observed frequently, supporting megakaryocytic lineage. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

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