Works (9)
Updated: July 5th, 2023 15:55
2013 journal article
Quantifiable Long-term Monitoring on Parks and Nature Preserves
SOUTHEASTERN NATURALIST, 12(2), 339–352.
TL;DR:
A case study at Hemlock Bluffs Nature Preserve in Cary, NC to model occupancy of focal species and demonstrate a replicable long-term protocol useful to parks and nature preserves with limited resources.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2011 journal article
Anchoring the dog to its relatives reveals new evolutionary breakpoints across 11 species of the Canidae and provides new clues for the role of B chromosomes
CHROMOSOME RESEARCH, 19(6), 685–708.
Contributors: n, R. Thomas n, V. Trifonov *, R. Wayne *, A. Graphodatsky * & M. Breen n
author keywords: B chromosomes; fragile breakage model; breakpoint reuse theory; fluorescence in situ hybridization; phylogenetic; Canidae
MeSH headings : Animals; Biological Evolution; Canidae / genetics; Chromosome Mapping; Chromosome Painting; Chromosomes, Artificial, Bacterial; Chromosomes, Mammalian / genetics; Cytogenetics; Dogs / genetics; Foxes / genetics; Genome; In Situ Hybridization, Fluorescence; Raccoon Dogs / genetics
TL;DR:
This work suggests that the complex karyotype rearrangements associated with speciation of the Canidae reflect unstable chromosome regions described by the fragile breakage model and provides evidence that these breakpoints are also recurrently associated with spontaneous canine cancers.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(Web of Science)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 6, 2018
2009 journal article
‘Putting our heads together’: insights into genomic conservation between human and canine intracranial tumors
Journal of Neuro-Oncology, 94(3), 333–349.
Contributors: R. Thomas n, S. Duke n, H. Wang n, T. Breen n, R. Higgins *, K. Linder n, P. Ellis *, C. Langford*
author keywords: Comparative genomic hybridization; Canine; Brain tumor; Chromosome; Microarray
MeSH headings : Animals; Brain Neoplasms / genetics; Brain Neoplasms / pathology; Chromosome Aberrations; Chromosome Mapping; Chromosomes, Human, Pair 1; Chromosomes, Human, Pair 22; Cluster Analysis; Dogs; Female; Gene Expression Regulation, Neoplastic; Genome / genetics; Glioma / genetics; Glioma / pathology; Humans; In Situ Hybridization, Fluorescence; Male; Meningeal Neoplasms / genetics; Meningeal Neoplasms / pathology; Meningioma / genetics; Meningioma / pathology
TL;DR:
A microarray-based comparative genomic hybridization analysis of 60 spontaneous canine intracranial tumors was performed to examine the degree to which dog and human patients exhibit aberrations of ancestrally related chromosome regions, consistent with a shared pathogenesis.
(via Semantic Scholar)
open access via europepmc.org (repository)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
15. Life on Land
(OpenAlex)
Sources: Web Of Science, Crossref, NC State University Libraries, ORCID
Added: August 6, 2018
2008 journal article
A genome assembly-integrated dog 1 Mb BAC microarray: a cytogenetic resource for canine cancer studies and comparative genomic analysis
CYTOGENETIC AND GENOME RESEARCH, 122(2), 110–121.
Contributors: R. Thomas*, S. Duke, E. Karlsson *, A. Evans *, P. Ellis *, K. Lindblad-Toh *, C. Langford*, M. Breen*
MeSH headings : Animals; Chromosomes / genetics; Comparative Genomic Hybridization; Cytogenetics; Databases, Nucleic Acid; Dogs; Genome / genetics; In Situ Hybridization, Fluorescence; Neoplasms / genetics; Oligonucleotide Array Sequence Analysis
TL;DR:
The dog genome sequence assembly is used to identify a framework panel of 2,097 bacterial artificial chromosome (BAC) clones, selected at intervals of approximately one megabase, which has enormous potential for aiding gene discovery through a comparative approach to molecular oncology.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 6, 2018
2007 article
A cytogenetically characterized, genome-anchored 10-Mb BAC set and CGH array for the domestic dog
JOURNAL OF HEREDITY, Vol. 98, pp. 474–484.
Contributors: R. Thomas n, S. Duke n, S. Bloom n, T. Breen n, A. Young n, E. Feiste n, E. Seiser n, P. Tsai n
MeSH headings : Animals; Chromosome Mapping; Chromosomes, Artificial, Bacterial / genetics; Dogs / genetics; Genome; In Situ Hybridization, Fluorescence; Nucleic Acid Hybridization; Oligonucleotide Array Sequence Analysis; Sensitivity and Specificity
TL;DR:
The value of a combined aCGH/FISH approach, together with a well-annotated dog genome assembly, in canine and comparative cancer studies is outlined.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 6, 2018
2007 journal article
A novel canine lymphoma cell line: A translational and comparative model for lymphoma research
LEUKEMIA RESEARCH, 31(12), 1709–1720.
Contributors: W. Kisseberth *, M. Nadella*, M. Breen n , R. Thomas n, S. Duke n, S. Murahari*, C. Kosarek*, W. Vernau*
author keywords: canine lymphoma; cell line; array comparative genomic hybridization; bioluminescent imaging; xenograft
MeSH headings : Animals; Biomedical Research; Cell Line, Tumor; Dogs; Immunophenotyping; Lymphoma / pathology; Mice; Mice, SCID; Neoplasm Transplantation; Transplantation, Heterologous
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 6, 2018
2007 review
Genome of the marsupial Monodelphis domestica reveals innovation in non-coding sequences
[Review of ]. NATURE, 447(7141), 167–U1.
Contributors: T. Mikkelsen *, M. Wakefield *, B. Aken *, C. Amemiya, J. Chang*, S. Duke n, M. Garber *, A. Gentles *
MeSH headings : Animals; Base Composition; Conserved Sequence / genetics; DNA Transposable Elements / genetics; Evolution, Molecular; Genome / genetics; Genomics; Humans; Opossums / genetics; Polymorphism, Single Nucleotide / genetics; Protein Biosynthesis; Synteny / genetics; X Chromosome Inactivation / genetics
TL;DR:
A high-quality draft of the genome sequence of the grey, short-tailed opossum is reported, indicating a strong influence of biased gene conversion on nucleotide sequence composition, and a relationship between chromosomal characteristics and X chromosome inactivation.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2007 journal article
The search for a marsupial XIC reveals a break with vertebrate synteny
Chromosome Research, 15(2), 137–146.
Contributors: L. Davidow *, M. Breen n , S. Duke n, P. Samollow *, J. McCarrey * & J. Lee *
author keywords: marsupial; Monodelphis domestica; noncoding RNA; TSIX; X-chromosome; XIC; X inactivation center; XIST
MeSH headings : Animals; Chromosome Walking; Computational Biology; Cytogenetic Analysis; DNA-Binding Proteins / genetics; Evolution, Molecular; Female; Genes, X-Linked; Genomics; Humans; Male; Monocarboxylic Acid Transporters / genetics; Monodelphis / genetics; RNA, Long Noncoding; RNA, Untranslated / genetics; Symporters; Synteny; Transcription Factors / genetics; Vertebrates / genetics; X Chromosome; X Chromosome Inactivation
TL;DR:
The failure to find XIST/TSIX in M. domestica may suggest that the ancestral XIC is too divergent to allow for detection by current methods, and argues that marsupial XCI does not require XIST and opens the search for alternative mechanisms of dosage compensation.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, Crossref, NC State University Libraries, ORCID
Added: August 6, 2018
journal article
Cytogenetic BAC map of the genome of Monodelphis domestica
Duke, S. E., Samallow, P., Mauceli, E., Lindblad-Toh, K., & Breen, M. Chromosome Research, 15, 3610–3670.
Source: NC State University Libraries
Added: August 6, 2018
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