Works (6)

Updated: July 5th, 2023 15:40

2019 journal article

Diphenhydramine pharmacokinetics after oral and intravenous administration of diphenhydramine and oral administration of dimenhydrinate to healthy dogs, and pharmacodynamic effect on histamine-induced wheal formation: a pilot study


By: S. Ehling n, W. Baeumer & M. Papich n

MeSH headings : Administration, Intravenous; Administration, Oral; Animals; Cross-Over Studies; Dimenhydrinate / administration & dosage; Dimenhydrinate / blood; Dimenhydrinate / pharmacokinetics; Diphenhydramine / administration & dosage; Diphenhydramine / blood; Diphenhydramine / pharmacokinetics; Dogs; Female; Half-Life; Histamine / adverse effects; Histamine Antagonists / pharmacokinetics; Male; Pilot Projects; Theophylline / blood; Urticaria / chemically induced; Urticaria / drug therapy
Sources: Web Of Science, ORCID
Added: April 2, 2019

2019 journal article

Neuromedin B Induces Acute Itch in Mice via the Activation of Peripheral Sensory Neurons

Acta Dermato Venereologica, 99(6), 587–893.

By: S. Ehling*, T. Fukuyama*, M. Ko, T. Olivry* & W. Bäumer

Contriutors: S. Ehling*, T. Fukuyama*, M. Ko, T. Olivry* & W. Bäumer

author keywords: acute itch; dorsal root ganglia; mast cells; neuromedin B; allergic dermatitis.
MeSH headings : Animals; Calcium / metabolism; Cell Degranulation; Cells, Cultured; Dermatitis, Allergic Contact / etiology; Female; Ganglia, Spinal / cytology; Ganglia, Spinal / metabolism; Gene Expression; Indoles / pharmacology; Injections, Intradermal; Macaca mulatta; Male; Mast Cells / metabolism; Mast Cells / physiology; Mice; Neurokinin B / administration & dosage; Neurokinin B / analogs & derivatives; Pruritus / chemically induced; Pyridines / pharmacology; RNA, Messenger / metabolism; Receptors, Bombesin / antagonists & inhibitors; Receptors, Bombesin / genetics; Receptors, Bombesin / metabolism; Sensory Receptor Cells / physiology; Single-Cell Analysis; Toluene 2,4-Diisocyanate
Sources: Web Of Science, Crossref, ORCID
Added: May 20, 2019

2017 journal article

Distinct neuronal populations in the basolateral and central amygdala are activated with acute pain, conditioned fear, and fear-conditioned analgesia


By: R. Butler n, S. Ehling n, M. Barbar n, J. Thomas n, M. Hughes n, C. Smith n, V. Pogorelov*, D. Aryal* ...

author keywords: Nociception; Contextual fear; Fear-conditioned analgesia; Amygdala; cFos; Neural circuits
MeSH headings : Acute Pain / physiopathology; Amygdala / physiopathology; Analgesia / methods; Animals; Central Amygdaloid Nucleus / metabolism; Conditioning, Psychological / physiology; Fear / physiology; Male; Mice, Inbred C57BL; Neurons / metabolism; Pain Management; Periaqueductal Gray / metabolism; Periaqueductal Gray / physiopathology
Sources: Web Of Science, ORCID
Added: August 6, 2018

2016 journal article

Allergic inflammation is augmented via histamine H4 receptor activation: The role of natural killer cells in vitro and in vivo


By: S. Ehling n, K. Rossbach*, S. Dunston n, H. Stark* & W. Baumer n

author keywords: Natural killer cells; Histamine H4 receptor; CCL17/TARC; Dermal dendritic cells; Allergic contact dermatitis
MeSH headings : Animals; Chemokine CCL17 / metabolism; Chemotaxis / drug effects; Coculture Techniques; Dendritic Cells / drug effects; Dendritic Cells / metabolism; Dermatitis, Atopic / immunology; Dermatitis, Atopic / metabolism; Disease Models, Animal; Female; Histamine / metabolism; Humans; Indoles / pharmacology; Killer Cells, Natural / drug effects; Killer Cells, Natural / metabolism; Mice; Mice, Inbred BALB C; Mice, Knockout; Ovalbumin; Piperazines / pharmacology; Pyrimidines / pharmacology; Receptors, G-Protein-Coupled / agonists; Receptors, G-Protein-Coupled / antagonists & inhibitors; Receptors, G-Protein-Coupled / genetics; Receptors, G-Protein-Coupled / metabolism; Receptors, Histamine / genetics; Receptors, Histamine / metabolism; Receptors, Histamine H4; Skin / cytology; Skin / drug effects; Skin / metabolism; Toluene 2,4-Diisocyanate / toxicity
Source: Web Of Science
Added: August 6, 2018

2015 journal article

Effects of azathioprine, 6-mercaptopurine, and 6-thioguanine on canine primary hepatocytes


By: K. LaDuke, S. Ehling*, J. Cullen* & W. Baeumer

MeSH headings : Animals; Azathioprine / administration & dosage; Azathioprine / pharmacology; Cell Line; Cell Survival / drug effects; Dogs; Dose-Response Relationship, Drug; Hepatocytes / drug effects; Immunosuppressive Agents / administration & dosage; Immunosuppressive Agents / pharmacology; Mercaptopurine / administration & dosage; Mercaptopurine / pharmacology; Thioguanine / administration & dosage; Thioguanine / pharmacology
Source: Web Of Science
Added: August 6, 2018

2015 journal article

Topically Administered Janus-Kinase Inhibitors Tofacitinib and Oclacitinib Display Impressive Antipruritic and Anti-Inflammatory Responses in a Model of Allergic Dermatitis


By: T. Fukuyama n, S. Ehling n, E. Cook n & W. Baeumer

MeSH headings : Administration, Oral; Administration, Topical; Animals; Anti-Inflammatory Agents / administration & dosage; Antipruritics / administration & dosage; Cytokines / metabolism; Dermatitis, Allergic Contact / drug therapy; Dermatitis, Allergic Contact / metabolism; Disease Models, Animal; Female; Inflammation / drug therapy; Inflammation / metabolism; Janus Kinases / antagonists & inhibitors; Lymph Nodes / drug effects; Lymph Nodes / metabolism; Mice; Mice, Inbred BALB C; Piperidines / administration & dosage; Pruritus / drug therapy; Pruritus / metabolism; Pyrimidines / administration & dosage; Pyrroles / administration & dosage; Skin / drug effects; Skin / metabolism; Sulfonamides / administration & dosage
Source: Web Of Science
Added: August 6, 2018