Sarah Orr

College of Sciences

2023 journal article

Salinity-induced ionoregulatory changes in the gill proteome of the mayfly, Neocloeon triangulifer


By: S. Orr n, L. Collins n, D. Jima n & D. Buchwalter n

author keywords: Proteomics; Salinity; Mayfly; Gill biology; Ion transport; Osmoregulation
MeSH headings : Animals; Ephemeroptera; Gills / metabolism; Salinity; Proteome / metabolism; Sodium Chloride / metabolism; Proteomics; Calcium Chloride; Water Pollutants, Chemical / metabolism; Aquatic Organisms / metabolism; Sodium-Potassium-Exchanging ATPase / metabolism; Ions / metabolism; Water / metabolism
TL;DR: The breadth of physiological functions in gills is demonstrated by exploring non-transport related pathways found in the dataset, including ATP synthesis, calcium signaling, and oxidative stress response, and the challenges of working with non-model species without fully sequenced and annotated genomes are discussed. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: January 30, 2023

2022 journal article

Assessing the P-crit in relation to temperature and the expression of hypoxia associated genes in the mayfly, Neocloeon triangulifer


By: J. Cochran n, S. Orr n & D. Buchwalter n

author keywords: Hypoxia; Pcrit; Gene expression; Temperature; Mayfly
MeSH headings : Animals; Ecosystem; Ephemeroptera; Hypoxia; Oxygen; Temperature
TL;DR: The hypothesis that the Pcrit is positively correlated with temperature in the mayfly, Neocloeon triangulifer, is tested and modest support for traditional interpretation of the P Criteria as a physiologically meaningful shift from aerobic to anaerobic metabolism in N. triangULifer is provided. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (Web of Science)
Source: Web Of Science
Added: February 28, 2022

2022 article

Weak differences in sensitivity to major ions by different larval stages of the mayfly Neocloeon triangulifer

Orr, S. E., Cochran, J. K., Wallace, I. G., Gray, R. W., Overmyer, G. E., & Buchwalter, D. B. (2022, June 1). FRESHWATER SCIENCE.

By: S. Orr n, J. Cochran n, I. Wallace n, R. Gray n, G. Overmyer n & D. Buchwalter n

author keywords: salinity; aquatic insects; mayflies; ontogenetic; major ions; toxicity; freshwater salinization; life stage sensitivity; model organism
TL;DR: The results indicate that younger N. triangulifer larvae may be more sensitive to major ions than mature larvae, and should be considered when experimentally using larger, late-stage N. TriangULifer larvae to study the physiological effects and acute toxicity of salinity. (via Semantic Scholar)
Source: Web Of Science
Added: March 7, 2022

2020 journal article

Chronic kidney disease in pregnant mothers affects maternal and fetal disposition of mercury


By: R. Moss*, H. George*, S. Nijhara*, S. Orr*, L. Joshee*, J. Barkin*, C. Bridges*

author keywords: Chronic kidney disease; Mercury; Heavy metals; Kidney
MeSH headings : Amniotic Fluid / chemistry; Animals; Brain / metabolism; Environmental Pollutants / pharmacokinetics; Environmental Pollutants / toxicity; Feces / chemistry; Female; Fetus / metabolism; Humans; Infant, Newborn; Kidney / drug effects; Kidney / metabolism; Kidney / pathology; Male; Maternal-Fetal Exchange; Mercury / blood; Mercury / metabolism; Mercury / urine; Methylmercury Compounds / pharmacokinetics; Methylmercury Compounds / toxicity; Placenta / chemistry; Pregnancy; Rats, Wistar; Renal Insufficiency, Chronic / metabolism; Tissue Distribution; Uterus / metabolism
TL;DR: The results of this study indicate that renal insufficiency in mothers leads to significant alterations in the way toxicants such as mercury are handled by maternal and fetal organs. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: Web Of Science
Added: May 8, 2020

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