Sarah E. Oxendine

Works (1)

Updated: July 5th, 2023 15:44

2013 article

Behavioral and neurogenomic transcriptome changes in wild-derived zebrafish with fluoxetine treatment

Wong, R. Y., Oxendine, S. E., & Godwin, J. (2013, January 1). BMC Genomics, Vol. 14.

By: R. Wong n, S. Oxendine n & J. Godwin n 

author keywords: Fluoxetine; Anxiety; Stress; SSRI; Genomic; Brain; RNA-sequencing; Zebrafish; Serotonin; GABA
MeSH headings : Animals; Anxiety / drug therapy; Anxiety / genetics; Behavior, Animal / drug effects; Fluoxetine / chemistry; Fluoxetine / pharmacology; Fluoxetine / therapeutic use; Humans; Male; Nervous System / drug effects; Nervous System / metabolism; Sequence Analysis, RNA; Selective Serotonin Reuptake Inhibitors / chemistry; Selective Serotonin Reuptake Inhibitors / pharmacology; Selective Serotonin Reuptake Inhibitors / therapeutic use; Stereoisomerism; Transcriptome / drug effects; Zebrafish / genetics
topics (OpenAlex): Neuroendocrine regulation and behavior; Zebrafish Biomedical Research Applications; Receptor Mechanisms and Signaling
TL;DR: It is demonstrated that fluoxetine reduces anxiety-related behaviors in wild-derived zebrafish and alters their neurogenomic state and two biological processes, lipid and amino acid metabolic synthesis that characterize differences in the fluoxettine treated fish are identified. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

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