Works (1)

Updated: July 5th, 2023 15:44

2013 journal article

Behavioral and neurogenomic transcriptome changes in wild-derived zebrafish with fluoxetine treatment


By: R. Wong n, S. Oxendine n & J. Godwin n

author keywords: Fluoxetine; Anxiety; Stress; SSRI; Genomic; Brain; RNA-sequencing; Zebrafish; Serotonin; GABA
MeSH headings : Animals; Anxiety / drug therapy; Anxiety / genetics; Behavior, Animal / drug effects; Fluoxetine / chemistry; Fluoxetine / pharmacology; Fluoxetine / therapeutic use; Humans; Male; Nervous System / drug effects; Nervous System / metabolism; Sequence Analysis, RNA; Selective Serotonin Reuptake Inhibitors / chemistry; Selective Serotonin Reuptake Inhibitors / pharmacology; Selective Serotonin Reuptake Inhibitors / therapeutic use; Stereoisomerism; Transcriptome / drug effects; Zebrafish / genetics
TL;DR: It is demonstrated that fluoxetine reduces anxiety-related behaviors in wild-derived zebrafish and alters their neurogenomic state and two biological processes, lipid and amino acid metabolic synthesis that characterize differences in the fluoxettine treated fish are identified. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

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