Shuang Fang Lim

Works (30)

Updated: December 18th, 2025 15:50

2022 article

Room-temperature upconverted superfluorescence

Huang, K., Green, K. K., Huang, L., Hallen, H., Han, G., & Lim, S. F. (2022, August 29). Nature Photonics, Vol. 8.

By: K. Huang *, K. Green n, L. Huang *, H. Hallen n , G. Han * & S. Lim n 

Contributors: H. Hallen n 

topics (OpenAlex): Luminescence Properties of Advanced Materials; Perovskite Materials and Applications; Solid State Laser Technologies
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Sources: Web Of Science, NC State University Libraries, ORCID
Added: September 12, 2022

2021 article

Three-Dimensional Colloidal Controlled Growth of Core–Shell Heterostructured Persistent Luminescence Nanocrystals

Huang, K., Li, Z., Li, Y., Yu, N., Gao, X., Huang, L., … Han, G. (2021, June 8). Nano Letters, Vol. 21, pp. 4903–4910.

By: K. Huang *, Z. Li *, Y. Li *, N. Yu *, X. Gao *, L. Huang *, S. Lim n , G. Han *

author keywords: persistent luminescence; core-shell nanoparticles; heterostructure; dual-excitation
MeSH headings : Luminescence; Nanoparticles; Nanostructures
topics (OpenAlex): Luminescence Properties of Advanced Materials; Luminescence and Fluorescent Materials; Lanthanide and Transition Metal Complexes
TL;DR: Benefitting from the well-matched crystal lattices between CaF2 and NaYF4, this colloidal synthesis makes it possible to prepare core-shell PLNPs with exquisite control of the compositions, shapes, and enhanced luminescence. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: July 19, 2021

2020 article

Efficient sub-15 nm cubic-phase core/shell upconversion nanoparticles as reporters for ensemble and single particle studies

Tan, M., Monks, M.-J., Huang, D., Meng, Y., Chen, X., Zhou, Y., … Chen, G. (2020, January 1). Nanoscale.

By: M. Tan *, M. Monks *, D. Huang *, Y. Meng*, X. Chen *, Y. Zhou n , S. Lim n , C. Würth *, U. Resch-Genger *, G. Chen *

topics (OpenAlex): Luminescence Properties of Advanced Materials; Radiation Detection and Scintillator Technologies; Perovskite Materials and Applications
TL;DR: The results underline the potential applicability of the described sub-15 nm cubic-phase core/shell UCNPs for ensemble- and single particle-level bioimaging. (via Semantic Scholar)
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Source: ORCID
Added: May 7, 2020

2020 article

Optical Nanoscale Thermometry: From Fundamental Mechanisms to Emerging Practical Applications

Bradac, C., Lim, S. F., Chang, H. C., & Aharonovich, I. (2020, May 18). Advanced Optical Materials, Vol. 8.

By: C. Bradac *, S. Lim n , H. Chang * & I. Aharonovich *

author keywords: all-optical thermosensors; fluorescent nanoparticles; nanoscale thermometry
topics (OpenAlex): Optical properties and cooling technologies in crystalline materials; Luminescence Properties of Advanced Materials; Thermal properties of materials
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Sources: Web Of Science, NC State University Libraries
Added: June 1, 2020

2019 article

Large available volume particles for enhanced deep UV local Raman sensing

Lim, S. F., Wirth, J., Bravo, A., Schuck, P., & Hallen, H. (2019, September 9). UV AND HIGHER ENERGY PHOTONICS: FROM MATERIALS TO APPLICATIONS 2019, Vol. 11086.

By: S. Lim n , J. Wirth n, A. Bravo *, P. Schuck * & H. Hallen n 

author keywords: resonance Raman; plasmon resonance; DUV; sensing particles; biosensing
topics (OpenAlex): Gold and Silver Nanoparticles Synthesis and Applications; Biosensors and Analytical Detection; Advanced biosensing and bioanalysis techniques
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Sources: Web Of Science, NC State University Libraries
Added: December 30, 2019

2018 article

DNA Methylation Detection Using Resonance and Nanobowtie-Antenna-Enhanced Raman Spectroscopy

Li, L., Lim, S. F., Puretzky, A., Riehn, R., & Hallen, H. D. (2018, June 1). Biophysical Journal, Vol. 114, pp. 2498–2506.

By: L. Li  n, S. Lim n , A. Puretzky *, R. Riehn n  & H. Hallen n 

MeSH headings : 5-Methylcytosine / metabolism; DNA Methylation; Nanotechnology; Spectrum Analysis, Raman
topics (OpenAlex): Advanced biosensing and bioanalysis techniques; Spectroscopy Techniques in Biomedical and Chemical Research; Spectroscopy and Quantum Chemical Studies
TL;DR: It is shown that DNA carrying 5-methylcytosine modifications or methylated DNA (m-DNA) can be distinguished from DNA with unmodified cytosine by Raman spectroscopy enhanced by both a bowtie nanoantenna and excitation resonance, and the Raman resonance gain profile is consistent with A-term expectations. (via Semantic Scholar)
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7. Affordable and Clean Energy (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2018 article

DNA methylation detection using UV nano bowtie antenna enhanced Raman spectroscopy

Hallen, H. D., Li, L., Lim, S. F., Puretzky, A., Riehn, R., & Long, B. J. (2018, September 7). UV AND HIGHER ENERGY PHOTONICS: FROM MATERIALS TO APPLICATIONS 2018, Vol. 10727.

By: H. Hallen n , L. Li n, S. Lim n , A. Puretzky *, R. Riehn n  & B. Long n

author keywords: Resonance Raman; methylation; cytosine; plasmonics; nano-antenna
topics (OpenAlex): Spectroscopy Techniques in Biomedical and Chemical Research; Advanced biosensing and bioanalysis techniques; Molecular Communication and Nanonetworks
UN Sustainable Development Goals Color Wheel
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7. Affordable and Clean Energy (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: December 3, 2018

2018 journal article

Motor-like DNA motion due to an ATP-hydrolyzing protein under nanoconfinement

Scientific Reports, 8(1).

By: M. Roushan n, Z. Azad n, S. Movahed n, P. Ray n, G. Livshits n, S. Lim n , K. Weninger n , R. Riehn n 

MeSH headings : Adenosine Triphosphate / metabolism; DNA / metabolism; DNA Ligases / metabolism; DNA Ligases / physiology; DNA-Binding Proteins / genetics; Diffusion; Escherichia coli / genetics; Escherichia coli / metabolism; Escherichia coli Proteins / metabolism; Escherichia coli Proteins / physiology; Motion; MutS DNA Mismatch-Binding Protein / metabolism; MutS DNA Mismatch-Binding Protein / physiology; NAD / metabolism
topics (OpenAlex): Nanopore and Nanochannel Transport Studies; Electrostatics and Colloid Interactions; Bacteriophages and microbial interactions
TL;DR: It is reported that long double-stranded DNA confined to quasi-1D nanochannels undergoes superdiffusive motion under the action of the enzyme T4 DNA ligase in the presence of necessary co-factors. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries, ORCID, NC State University Libraries
Added: August 6, 2018

2018 article

Optical Temperature Sensing With Infrared Excited Upconversion Nanoparticles

Green, K., Huang, K., Pan, H., Han, G., & Lim, S. F. (2018, September 24). Frontiers in Chemistry, Vol. 6.

By: K. Green n, K. Huang *, H. Pan n, G. Han * & S. Lim n 

author keywords: upconversion thermal sensing; pulsed excitation; 800 nm; 980 nm; local thermal heating; DNA denaturation
topics (OpenAlex): Spectroscopy Techniques in Biomedical and Chemical Research; Photoreceptor and optogenetics research; Luminescence Properties of Advanced Materials
TL;DR: These studies provide evidence for the feasibility of exploring protein-DNA interactions at the single molecule scale, using UCNPs as a reporter, and confirm the applicability of infrared imaging at excitation intensities compatible with single nanoparticle tracking. (via Semantic Scholar)
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6. Clean Water and Sanitation (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: October 16, 2018

2017 article

Influence of Gold Metallodielectric Partial-Shell Geometrical Irregularities on Dark Plasmon Resonances

Wirth, J., Hallen, H., & Lim, S. F. (2017, July 5). The Journal of Physical Chemistry C, Vol. 121, pp. 15937–15942.

By: J. Wirth n, H. Hallen n  & S. Lim n 

topics (OpenAlex): Gold and Silver Nanoparticles Synthesis and Applications; Plasmonic and Surface Plasmon Research; Orbital Angular Momentum in Optics
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Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2017 journal article

Nanoplasmonic Upconverting Nanoparticles as Orientation Sensors for Single Particle Microscopy

Scientific Reports, 7(1).

By: K. Green n, J. Wirth n & S. Lim n 

topics (OpenAlex): Microfluidic and Bio-sensing Technologies; Gold and Silver Nanoparticles Synthesis and Applications; Near-Field Optical Microscopy
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Sources: Crossref, NC State University Libraries, NC State University Libraries
Added: August 6, 2018

2016 journal article

Enhancement of Upconverted Fluorescence by Interference Layers

Small, 13(6), 1602846.

By: J. Wirth n, K. Green n, M. O'Connor n & S. Lim n 

topics (OpenAlex): Quantum Dots Synthesis And Properties; Optical properties and cooling technologies in crystalline materials; Gold and Silver Nanoparticles Synthesis and Applications; Luminescence Properties of Advanced Materials; Luminescence and Fluorescent Materials
TL;DR: Both experiments and calculations show emission enhancement at an interference layer thickness of about 740 ± 20 nm, where such tolerance and the planar design, leads to ease in implementation in applications. (via Semantic Scholar)
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7. Affordable and Clean Energy (Web of Science; OpenAlex)
Sources: Crossref, NC State University Libraries, NC State University Libraries
Added: August 6, 2018

2016 journal article

Optical investigation of gold shell enhanced 25 nm diameter upconverted fluorescence emission

Nanotechnology, 27(13), 135201.

By: K. Green n, J. Wirth* & S. Lim* 

author keywords: plasmonic; upconversion; gold shell; fluorescence; time-resolved; AFM; structure and optical correlation
topics (OpenAlex): Luminescence Properties of Advanced Materials; Quantum Dots Synthesis And Properties; Luminescence and Fluorescent Materials
TL;DR: It is demonstrated that fluorescence enhancement is based on the photonic properties of single, isolated particles and the rate of photon emission is not suppressed, as would be expected for a metallic cavity, but rather enhanced because the metal shell acts as an optical antenna, with differing efficiency at different wavelengths. (via Semantic Scholar)
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7. Affordable and Clean Energy (Web of Science; OpenAlex)
Sources: Crossref, NC State University Libraries, NC State University Libraries
Added: August 6, 2018

2015 journal article

Enhancement of single particle rare earth doped NaYF4: Yb, Er emission with a gold shell

Nanotechnology, 26(2).

By: L. Li, K. Green, H. Hallen  & S. Lim 

Source: NC State University Libraries
Added: August 6, 2018

2015 journal article

Interference of ATP with the fluorescent probes YOYO-1 and YOYO-3 modifies the mechanical properties of intercalator-stained DNA confined in nanochannels

Microchimica Acta, 182(7-8), 1561–1565.

By: M. Roushan n, Z. Azad n, S. Lim n , H. Wang n  & R. Riehn n 

Contributors: M. Roushan n, Z. Azad n, S. Lim n , H. Wang n  & R. Riehn n 

author keywords: DNA; ATP; Intercalating dye; YOYO-1; DAPI; Nanofluidics
topics (OpenAlex): Nanopore and Nanochannel Transport Studies; Microfluidic and Capillary Electrophoresis Applications; DNA and Nucleic Acid Chemistry
TL;DR: Investigation of the mechanical properties of DNA stained with the fluorescent intercalating dyes YOYO-1 and YoyO-3 as a function of ATP concentrations by stretching single molecules in nanofluidic channels finds negligible effects if DNA is visualized with the minor groove-binding probe 4′,6-diamidino-2-phenylindole. (via Semantic Scholar)
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6. Clean Water and Sanitation (OpenAlex)
Sources: Web Of Science, NC State University Libraries, ORCID, Crossref
Added: August 6, 2018

2015 conference paper

Multifunctional diagnostic, nanothermometer, and photothermal nano-devices

Ultrafast nonlinear imaging and spectroscopy iii, 9584.

By: K. Green, J. Wirth, M. O'Connor & S. Lim 

Source: NC State University Libraries
Added: August 6, 2018

2014 journal article

Enhancement of single particle rare earth doped NaYF4: Yb, Er emission with a gold shell

Nanotechnology, 26(2), 025101.

By: L. Li  n, K. Green n, H. Hallen n  & S. Lim n 

author keywords: bioimaging; upconversion; near infrared
topics (OpenAlex): Luminescence Properties of Advanced Materials; Quantum Dots Synthesis And Properties; Random lasers and scattering media
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Sources: Crossref, ORCID, NC State University Libraries
Added: August 13, 2019

2014 journal article

Probing transient protein-mediated DNA linkages using nanoconfinement

Biomicrofluidics, 8(3).

By: M. Roushan, P. Kaur, A. Karpusenko, P. Countryman, C. Ortiz, S. Lim , H. Wang , R. Riehn 

Source: NC State University Libraries
Added: August 6, 2018

2013 journal article

Chromatin modification mapping in nanochannels

Biomicrofluidics, 7(6), 064105.

By: S. Lim n , A. Karpusenko n, A. Blumers  n, D. Streng n & R. Riehn n 

Contributors: S. Lim n , A. Karpusenko n, A. Blumers  n, D. Streng n & R. Riehn n 

topics (OpenAlex): Genomics and Chromatin Dynamics; Advanced biosensing and bioanalysis techniques; DNA and Nucleic Acid Chemistry
TL;DR: It is determined that the major difficulty in transitioning the mapping method to site-specific profiling within single genomic molecules is the interference of naturally aggregating, off-the shelf antibodies with the internal structure of chromatin. (via Semantic Scholar)
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14. Life Below Water (OpenAlex)
Sources: Crossref, NC State University Libraries, ORCID, NC State University Libraries
Added: August 6, 2018

2012 journal article

Fluctuation modes of nanoconfined DNA

Journal of Applied Physics, 111(2), 024701.

By: A. Karpusenko n, J. Carpenter n, C. Zhou n, S. Lim n , J. Pan n & R. Riehn n 

topics (OpenAlex): Nanopore and Nanochannel Transport Studies; Microfluidic and Capillary Electrophoresis Applications; Electrostatics and Colloid Interactions
TL;DR: An experimental investigation of the magnitude of length and density fluctuations in DNA that has been stretched in nanofluidic channels finds that the experimental data can be described using a one-dimensional overdamped oscillator chain with nonzero equilibrium spring length and that a chain of discrete oscillators yields a better description than a continuous chain. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries, NC State University Libraries
Added: August 6, 2018

2012 journal article

Near-field enhanced ultraviolet resonance Raman spectroscopy using aluminum bow-tie nano-antenna

Applied Physics Letters, 101(11).

By: L. Li, S. Lim , A. Puretzky, R. Riehn  & H. Hallen 

Source: NC State University Libraries
Added: August 6, 2018

2011 journal article

DNA methylation profiling in nanochannels

Biomicrofluidics, 5(3).

By: S. Lim , A. Karpusenko, J. Sakon, J. Hook, T. Lamar & R. Riehn 

Source: NC State University Libraries
Added: August 6, 2018

2011 journal article

Density fluctuations dispersion relationship for a polymer confined to a nanotube

Applied Physics Letters, 98(25), 253704.

By: J. Carpenter n, A. Karpusenko n, J. Pan n, S. Lim n  & R. Riehn n 

Contributors: J. Carpenter n

topics (OpenAlex): Nanopore and Nanochannel Transport Studies; Electrostatics and Colloid Interactions; Force Microscopy Techniques and Applications
TL;DR: It is found that for highly elongated molecules a Rouse description is consistent with observations at sufficiently large length scales and that for strongly fluctuating molecules, or short length scales, such Rouse modes cannot be detected due to strong mixing of fluctuation modes. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries, ORCID, NC State University Libraries
Added: August 6, 2018

2010 journal article

Epigenetic Analysis of Chromatin in Nanochannels

Biophysical Journal, 98(3), 600a.

By: D. Streng n, S. Lim n  & R. Riehn n 

topics (OpenAlex): Nanopore and Nanochannel Transport Studies; Genomics and Chromatin Dynamics; RNA modifications and cancer
TL;DR: It is shown here that the concept by nanoconfinement can be extended to chromatin, or DNA complexed to histones, and that the stretching is within the range expected from the de Gennes theory. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: September 8, 2020

2009 article

Stretching chromatin through confinement

Streng, D. E., Lim, S. F., Pan, J., Karpusenka, A., & Riehn, R. (2009, January 1). Lab on a Chip, Vol. 9, pp. 2772–2774.

By: D. Streng n, S. Lim n , J. Pan n, A. Karpusenka n & R. Riehn n 

Contributors: D. Streng n

MeSH headings : Chromatin / chemistry; Chromatin / genetics; DNA / chemistry; DNA / genetics; Microfluidic Analytical Techniques / methods
topics (OpenAlex): Advanced biosensing and bioanalysis techniques; DNA and Nucleic Acid Chemistry; RNA and protein synthesis mechanisms
TL;DR: The stretching of chromatin to about 12 basepairs/nm enables location-resolved optical investigation of the nucleic material with a resolution of up to 6 kbp and finds that chromatin is 2.5 times more compact in its stretched state. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 6, 2018

2009 journal article

Upconverting nanophosphors for bioimaging

Nanotechnology, 20(40), 405701.

By: S. Lim n , R. Riehn n , C. Tung *, W. Ryu *, R. Zhuo*, J. Dalland *, R. Austin *

Contributors: S. Lim n 

MeSH headings : Diagnostic Imaging / methods; Nanoparticles / chemistry; Nanotechnology / methods
topics (OpenAlex): Quantum Dots Synthesis And Properties; Luminescence Properties of Advanced Materials; Nanocluster Synthesis and Applications
TL;DR: Sub-10 nm, upconverting rare earth oxide UCNPs synthesized by a combustion method that can be stably suspended in water when amine modified are demonstrated and show specific surface immobilization onto patterned gold surfaces. (via Semantic Scholar)
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Sources: Crossref, NC State University Libraries, ORCID, NC State University Libraries
Added: August 6, 2018

2008 article

The Sackler Colloquium on promises and perils in nanotechnology for medicine

Austin, R. H., & Lim, S.-fang. (2008, November 4). Proceedings of the National Academy of Sciences, Vol. 105, pp. 17217–17221.

By: R. Austin * & S. Lim n 

author keywords: nanomaterials; upconversion
MeSH headings : Asbestos / chemistry; Medical Laboratory Science / trends; Nanostructures; Nanotechnology / trends; Particle Size; Titanium / chemistry; X-Ray Diffraction
topics (OpenAlex): Molecular Communication and Nanonetworks; Photoreceptor and optogenetics research; bioluminescence and chemiluminescence research
TL;DR: The Sackler Colloquium entitled “Nanomaterials in Biology and Medicine: Promises and Perils” was held on April 10–11, 2007 and a representative sampling of 17 of the invited talks ranging over the topics presented is assembled. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2005 journal article

In Vivo and Scanning Electron Microscopy Imaging of Upconverting Nanophosphors inCaenorhabditiselegans

Nano Letters, 6(2), 169–174.

By: S. Lim* , R. Riehn* , W. Ryu *, N. Khanarian*, C. Tung *, D. Tank *, R. Austin *

Contributors: S. Lim* 

MeSH headings : Animals; Caenorhabditis elegans / chemistry; Microscopy, Electron, Scanning / methods; Nanostructures / chemistry; Particle Size; Phosphorus / chemistry; Sensitivity and Specificity; Spectrometry, X-Ray Emission / methods; Surface Properties
topics (OpenAlex): Luminescence Properties of Advanced Materials; Quantum Dots Synthesis And Properties; Machine Learning in Materials Science
TL;DR: It is shown here that upconversion phosphors can be imaged both by infrared excitation and in a scanning electron microscope, and it is confirmed using energy-dispersive X-ray analysis that the up-conversion nanoparticles can be identified in a scan electron microscope at high spatial resolution. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
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7. Affordable and Clean Energy (OpenAlex)
Sources: Crossref, NC State University Libraries, ORCID
Added: July 23, 2019

2005 journal article

Restriction mapping in nanofluidic devices

Proceedings of the National Academy of Sciences, 102(29), 10012–10016.

By: R. Riehn* , M. Lu*, Y. Wang*, S. Lim* , E. Cox* & R. Austin *

Contributors: R. Riehn* 

MeSH headings : DNA / metabolism; DNA Restriction Enzymes / metabolism; Magnesium; Microscopy; Nanostructures; Nanotechnology / methods; Restriction Mapping / methods
topics (OpenAlex): Nanopore and Nanochannel Transport Studies; Microfluidic and Capillary Electrophoresis Applications; Advanced biosensing and bioanalysis techniques
TL;DR: This work has performed restriction mapping of DNA molecules using restriction endonucleases in nanochannels with diameters of 100-200 nm and has been able to measure the positions of restriction sites with a precision of approximately 1.5 kbp in 1 min using single DNA molecules. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries, ORCID
Added: July 23, 2019

2005 journal article

Suppression of Green Emission in a New Class of Blue-Emitting Polyfluorene Copolymers with Twisted Biphenyl Moieties

Advanced Functional Materials, 15(6), 981–988.

By: S. Lim* , R. Friend *, I. Rees*, J. Li *, Y. Ma *, K. Robinson*, A. Holmes *, E. Hennebicq*, D. Beljonne*, F. Cacialli *

topics (OpenAlex): Organic Electronics and Photovoltaics; Organic Light-Emitting Diodes Research; Luminescence and Fluorescent Materials
Sources: Crossref, NC State University Libraries
Added: January 7, 2022

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