Shobhan Gaddameedhi

Yan, S., Gaddameedhi, S., & Sobol, R. W. (2024). Inspiring basic and applied research in genome integrity mechanisms: Dedication to Samuel H. Wilson. Environmental and Molecular Mutagenesis. https://doi.org/10.1002/em.22595

Mishra, S. K., & Gaddameedhi, S. (2023, January 20). A new role of TRPM8 in circadian rhythm and molecular clock. ACTA PHYSIOLOGICA, Vol. 1. https://doi.org/10.1111/apha.13934

Zhang, J., Zhang, F., Porter, K. I., Dakup, P. P., Wang, S., Robertson, G. P., … Zhu, J. (2023, September 20). Telomere dysfunction in Tert knockout mice delays Braf<SUP>V600E</SUP>-induced melanoma development. INTERNATIONAL JOURNAL OF CANCER, Vol. 9. https://doi.org/10.1002/ijc.34713

Koritala, B. S. C., Dakup, P. P., Porter, K. I., & Gaddameedhi, S. (2023). The impact of shift-work light conditions on tissue-specific circadian rhythms of canonical clock genes: insights from a mouse model study. F1000Research. https://doi.org/10.12688/f1000research.136998.1

Koritala, B. S. C., Dakup, P. P., Porter, K. I., & Gaddameedhi, S. (2023). The impact of shift-work light conditions on tissue-specific circadian rhythms of canonical clock genes: insights from a mouse model study. F1000Research. https://doi.org/10.12688/f1000research.136998.3

Koritala, B. S. C., Dakup, P. P., Porter, K. I., Gaddameedhi, S., P., D. P., & Koritala, B. S. C. (2023). The impact of shift-work light conditions on tissue-specific circadian rhythms of canonical clock genes: insights from a mouse model study [version 1; peer review: 1 approved, 1 approved with reservations] [Version 1;]. F1000Research. https://doi.org/10.12688/f1000research.136998.2

CIRCADIAN DYSREGULATION OF HUMAN DNA REPAIR GENES AND ELEVATED DNA DAMAGE IN SIMULATED NIGHT SHIFT SCHEDULE. (2022). Sleep. Retrieved from https://publons.com/wos-op/publon/54906417/

Koritala, B. S. C., Porter, K. I., Sarkar, S., & Gaddameedhi, S. (2022). Circadian disruption and cisplatin chronotherapy for mammary carcinoma. TOXICOLOGY AND APPLIED PHARMACOLOGY, 436. https://doi.org/10.1016/j.taap.2022.115863

Goodenow, D., Greer, A. J., Cone, S. J., & Gaddameedhi, S. (2022). Circadian effects on UV-induced damage and mutations. MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH, 789. https://doi.org/10.1016/j.mrrev.2022.108413

Kelly, M. R., Yuen, F., Satterfield, B. C., Auchus, R. J., Gaddameedhi, S., Van Dongen, H. P. A., & Liu, P. Y. (2022). Endogenous Diurnal Patterns of Adrenal and Gonadal Hormones During a 24-Hour Constant Routine After Simulated Shift Work. JOURNAL OF THE ENDOCRINE SOCIETY, 6(12). https://doi.org/10.1210/jendso/bvac153

Dakup, P. P., Greer, A. J., & Gaddameedhi, S. (2022, February 3). Let's talk about sex: A biological variable in immune response against melanoma. PIGMENT CELL & MELANOMA RESEARCH, Vol. 35. https://doi.org/10.1111/pcmr.13028

Kyle, J. E., Bramer, L. M., Claborne, D., Stratton, K. G., Bloodsworth, K. J., Teeguarden, J. G., … Van Dongen, H. P. A. (2022). Simulated Night- Shift Schedule Disrupts the Plasma Lipidome and Reveals Early Markers of Cardiovascular Disease Risk. NATURE AND SCIENCE OF SLEEP, 14, 981–994. https://doi.org/10.2147/NSS.S363437

Muck, R. A., Hudson, A. N., Honn, K. A., Gaddameedhi, S., & Van Dongen, H. P. A. (2022). Working around the Clock: Is a Person's Endogenous Circadian Timing for Optimal Neurobehavioral Functioning Inherently Task-Dependent? CLOCKS & SLEEP, 4(1), 23–36. https://doi.org/10.3390/clockssleep4010005

Sarkar, S., Porter, K. I., Dakup, P. P., Gajula, R. P., Koritala, B. S. C., Hylton, R., … Gaddameedhi, S. (2021, July 6). Circadian clock protein BMAL1 regulates melanogenesis through MITF in melanoma cells. PIGMENT CELL & MELANOMA RESEARCH, Vol. 34. https://doi.org/10.1111/pcmr.12998

Hayter, E. A., Wehrens, S. M. T., Van Dongen, H. P. A., Stangherlin, A., Gaddameedhi, S., Crooks, E., … Bechtold, D. A. (2021). Distinct circadian mechanisms govern cardiac rhythms and susceptibility to arrhythmia. NATURE COMMUNICATIONS, 12(1). https://doi.org/10.1038/s41467-021-22788-8

Liu, P. Y., Irwin, M. R., Krueger, J. M., Gaddameedhi, S., & Dongen, H. P. A. V. (2021). Night shift schedule alters endogenous regulation of circulating cytokines. Neurobiology of Sleep and Circadian Rhythms, 10, 100063. https://doi.org/10.1016/j.nbscr.2021.100063

Koritala, B. S. C., Porter, K. I., Arshad, O. A., Gajula, R. P., Mitchell, H. D., Arman, T., … Gaddameedhi, S. (2021). Night shift schedule causes circadian dysregulation of DNA repair genes and elevated DNA damage in humans. JOURNAL OF PINEAL RESEARCH, 70(3). https://doi.org/10.1111/jpi.12726

Xu, T., Cheng, D., Zhao, Y., Zhang, J., Zhu, X., Zhang, F., … Zhu, J. (2021). Polymorphic tandem DNA repeats activate the human telomerase reverse transcriptase gene. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 118(26). https://doi.org/10.1073/pnas.2019043118

Khalyfa, A., Gaddameedhi, S., Crooks, E., Zhang, C., Li, Y., Qiao, Z., … Gozal, D. (2020). Circulating Exosomal miRNAs Signal Circadian Misalignment to Peripheral Metabolic Tissues. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 21(17). https://doi.org/10.3390/ijms21176396

Dakup, P. P., Porter, K. I., Little, A. A., Zhang, H., & Gaddameedhi, S. (2020). Sex differences in the association between tumor growth and T cell response in a melanoma mouse model. Cancer Immunology, Immunotherapy, 69(10), 2157–2162. https://doi.org/10.1007/s00262-020-02643-3

Solar ultraviolet-induced DNA damage response: Melanocytes story in transformation to environmental melanomagenesis. (2020). Environmental and Molecular Mutagenesis. https://doi.org/10.1002/em.22370

Dakup, P. P., Porter, K. I., & Gaddameedhi, S. (2020). The circadian clock protects against acute radiation-induced dermatitis. Toxicology and Applied Pharmacology, 399, 115040. https://doi.org/10.1016/j.taap.2020.115040

The circadian clock protects against ionizing radiation-induced cardiotoxicity. (2020). FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. https://doi.org/10.1096/fj.201901850rr

Cardiac autonomic activity during simulated shift work. (2019). Industrial Health. https://doi.org/10.2486/INDHEALTH.2018-0044

It's About Time: Advances in Understanding the Circadian Regulation of DNA Damage and Repair in Carcinogenesis and Cancer Treatment Outcomes. (2019). Yale Journal of Biology and Medicine. Retrieved from https://publons.com/wos-op/publon/32413204/

It's About Time: Advances in Understanding the Circadian Regulation of DNA Damage and Repair in Carcinogenesis and Cancer Treatment Outcomes. (2019). The Yale Journal of Biology and Medicine. Retrieved from https://europepmc.org/articles/PMC6585512

Circadian clock protects against radiation-induced dermatitis and cardiomyopathy in mice. (2018). Cancer Research. https://doi.org/10.1158/1538-7445.AM2018-4159

Circulating Plasma Exosomes May Signal Circadian Clock Misalignment to Peripheral Tissues. (2018). American Journal of Respiratory and Critical Care Medicine. Retrieved from https://publons.com/wos-op/publon/35726971/

Skene, D. J., Skornyakov, E., Chowdhury, N. R., Gajula, R. P., Middleton, B., Satterfield, B. C., … Gaddameedhi, S. (2018). Separation of circadian- and behavior-driven metabolite rhythms in humans provides a window on peripheral oscillators and metabolism. Proceedings of the National Academy of Sciences, 115(30), 7825–7830. https://doi.org/10.1073/pnas.1801183115

The circadian clock regulates cisplatin-induced toxicity and tumor regression in melanoma mouse and human models. (2018). Oncotarget. https://doi.org/10.18632/oncotarget.24539

UV-B-Induced Erythema in Human Skin: The Circadian Clock Is Ticking. (2018). The Journal of Investigative Dermatology. https://doi.org/10.1016/j.jid.2017.09.002

Chronopharmacology of cisplatin: role of the circadian rhythm in modulating cisplatin-induced toxicity in melanoma mouse model. (2017). Cancer Research. https://doi.org/10.1158/1538-7445.AM2017-1120

Impact of the Circadian Clock on UV-Induced DNA Damage Response and Photocarcinogenesis. (2017). Photochemistry & Photobiology. https://doi.org/10.1111/PHP.12662

Shift Work: Disrupted Circadian Rhythms and Sleep-Implications for Health and Well-Being. (2017). Current Sleep Medicine Reports. https://doi.org/10.1007/s40675-017-0071-6

Chronopharmacology of cisplatin: Role of the circadian rhythm in modulating the cisplatin transporters levels. (2016). The FASEB Journal. Retrieved from https://publons.com/wos-op/publon/32413213/

Circadian Clock, Cancer, and Chemotherapy. (2015). Biochemistry. https://doi.org/10.1021/BI5007354

Commentary: Chemiexcitation of melanin derivatives induces DNA photoproducts long after UV exposure. (2015). Frontiers in Physiology. https://doi.org/10.3389/fphys.2015.00276

Development and validation of a new transgenic hairless albino mouse as a mutational model for potential assessment of photocarcinogenicity. (2015). Mutation Research. Genetic Toxicology and Environmental Mutagenesis. https://doi.org/10.1016/j.mrgentox.2015.08.001

Oncogenic BRAF(V600E) Induces Clastogenesis and UVB Hypersensitivity. (2015). Cancers. https://doi.org/10.3390/cancers7020825

The Circadian Clock Controls Sunburn Apoptosis and Erythema in Mouse Skin. (2015). Journal of Investigative Dermatology. https://doi.org/10.1038/JID.2014.508

DNA repair synthesis and ligation affect the processing of excised oligonucleotides generated by human nucleotide excision repair. (2014). The Journal of Biological Chemistry. https://doi.org/10.1074/jbc.m114.597088

Dual modes of CLOCK:BMAL1 inhibition mediated by Cryptochrome and Period proteins in the mammalian circadian clock. (2014). Genes & Development. https://doi.org/10.1101/gad.249417.114

Highly specific and sensitive method for measuring nucleotide excision repair kinetics of ultraviolet photoproducts in human cells. (2014). Nucleic Acids Research. https://doi.org/10.1093/NAR/GKT1179

DNA Damage-Specific Control of Cell Death by Cryptochrome in p53-Mutant Ras-Transformed Cells. (2013). Cancer Research. https://doi.org/10.1158/0008-5472.CAN-12-1994

Nucleotide excision repair in human cells: fate of the excised oligonucleotide carrying DNA damage in vivo. (2013). The Journal of Biological Chemistry. https://doi.org/10.1074/jbc.m113.482257

Effect of circadian clock mutations on DNA damage response in mammalian cells. (2012). Cell Cycle (Georgetown, Tex.). https://doi.org/10.4161/cc.21771

Gaddameedhi, S., Selby, C. P., Kaufmann, W. K., Smart, R. C., & Sancar, A. (2011). Control of skin cancer by the circadian rhythm. Proceedings of the National Academy of Sciences, 108(46), 18790–18795. https://doi.org/10.1073/pnas.1115249108

Melanoma and DNA damage from a distance (farstander effect). (2011). Pigment Cell & Melanoma Research. https://doi.org/10.1111/j.1755-148x.2010.00805.x

Similar nucleotide excision repair capacity in melanocytes and melanoma cells. (2010). Cancer Research. https://doi.org/10.1158/0008-5472.can-10-0095

Association between the unfolded protein response, induced by 2-deoxyglucose, and hypersensitivity to cisplatin: a mechanistic study employing molecular genomics. (2009). Journal of Cancer Research and Therapeutics. https://doi.org/10.4103/0973-1482.55146

Loss of cryptochrome reduces cancer risk in p53 mutant mice. (2009). Proceedings of the National Academy of Sciences of the United States of America. https://doi.org/10.1073/pnas.0813028106

Deciphering the association between up-regulation of glucose regulated protein of Mr-78 kDa (GRP78) and hypersensitivity to cisplatin employing comparative genomics. (2008). The FASEB Journal. Retrieved from https://publons.com/wos-op/publon/54906423/

Up-regulation of glucose regulated protein of M-r-78KDa (GRP78) followed by cisplatin treatment leads to mitochondrial mediated apoptosis through caspase-2 activation. (2006). Cancer Research. Retrieved from https://publons.com/wos-op/publon/54906422/

In-gel precipitation of enzymatically released phosphate. (2004). Analytical Biochemistry. https://doi.org/10.1016/j.ab.2004.07.010