@article{pfisterer_corps_jennings_2019, title={Pathology in Practice}, volume={254}, ISSN={["1943-569X"]}, DOI={10.2460/javma.254.6.681}, number={6}, journal={JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION}, author={Pfisterer, Bianca R. and Corps, Kara N. and Jennings, Samuel H.}, year={2019}, month={Mar}, pages={681–683} }
 @article{mavromatis_oura_jennings_2015, title={What is your diagnosis?}, volume={247}, number={5}, journal={Journal of the American Veterinary Medical Association}, author={Mavromatis, M. V. and Oura, T. J. and Jennings, S. H.}, year={2015}, pages={471–473} }
 @article{niemuth_de voe_jennings_loomis_troan_2014, title={Malignant hypertension and retinopathy in a western lowland gorilla (Gorilla gorilla gorilla)}, volume={43}, ISSN={["1600-0684"]}, DOI={10.1111/jmp.12114}, abstractNote={A 34-year-old western lowland gorilla presented with peracute blindness.Clinical evaluation, diagnostic imaging, laboratory analyses, blood pressure measurements, and necropsy were performed.The clinical and postmortem findings supported malignant hypertension.We describe a case of naturally occurring hypertensive encephalopathy and retinopathy in a gorilla.}, number={4}, journal={JOURNAL OF MEDICAL PRIMATOLOGY}, publisher={Wiley-Blackwell}, author={Niemuth, Jennifer N. and De Voe, Ryan S. and Jennings, Samuel H. and Loomis, Michael R. and Troan, Brigid V.}, year={2014}, month={Aug}, pages={276–279} }
 @article{stevens_montgomery_phillips_wester_jennings_2014, title={Pathology in Practice}, volume={245}, ISSN={["1943-569X"]}, DOI={10.2460/javma.245.1.57}, number={1}, journal={JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION}, author={Stevens, Brenda J. and Montgomery, Stephanie A. and Phillips, Kathryn L. and Wester, Maggie W. and Jennings, Samuel H.}, year={2014}, month={Jul}, pages={57–59} }
 @article{balakrishnan_pritchard_ericson_grindem_phillips_jennings_mathews_tran_birkenheuer_breitschwerdt_et al._2014, title={Prostatitis, Steatitis, and Diarrhea in a Dog following Presumptive Flea-Borne Transmission of Bartonella henselae}, volume={52}, ISSN={0095-1137 1098-660X}, url={http://dx.doi.org/10.1128/JCM.00942-14}, DOI={10.1128/jcm.00942-14}, abstractNote={Bartonella henselae is increasingly associated with a variety of pathological entities, which are often similar in dogs and human patients. Following an acute flea infestation, a dog developed an unusual clinical presentation for canine bartonellosis. Comprehensive medical, microbiological, and surgical interventions were required for diagnosis and to achieve a full recovery.}, number={9}, journal={Journal of Clinical Microbiology}, publisher={American Society for Microbiology}, author={Balakrishnan, N. and Pritchard, J. and Ericson, M. and Grindem, C. and Phillips, K. and Jennings, S. and Mathews, K. and Tran, H. and Birkenheuer, A. J. and Breitschwerdt, Edward and et al.}, editor={Munson, E.Editor}, year={2014}, month={Jun}, pages={3447–3452} }
 @article{newman_prange_jennings_barlow_davis_2013, title={Pharmacokinetics of tobramycin following intravenous, intramuscular, and intra-articular administration in healthy horses}, volume={36}, ISSN={["1365-2885"]}, DOI={10.1111/jvp.12048}, abstractNote={The objectives of this study were to examine the pharmacokinetics of tobramycin in the horse following intravenous (IV), intramuscular (IM), and intra‐articular (IA) administration. Six mares received 4 mg/kg tobramycin IV, IM, and IV with concurrent IA administration (IV+IA) in a randomized 3‐way crossover design. A washout period of at least 7 days was allotted between experiments. After IV administration, the volume of distribution, clearance, and half‐life were 0.18 ± 0.04 L/kg, 1.18 ± 0.32 mL·kg/min, and 4.61 ± 1.10 h, respectively. Concurrent IA administration could not be demonstrated to influence IV pharmacokinetics. The mean maximum plasma concentration ( C max ) after IM administration was 18.24 ± 9.23 μg/mL at 1.0 h (range 1.0–2.0 h), with a mean bioavailability of 81.22 ± 44.05%. Intramuscular administration was well tolerated, despite the high volume of drug administered (50 mL per 500 kg horse). Trough concentrations at 24 h were below 2 μg/mL in all horses after all routes of administration. Specifically, trough concentrations at 24 h were 0.04 ± 0.01 μg/mL for the IV route, 0.04 ± 0.02 μg/mL for the IV/IA route, and 0.02 ± 0.02 for the IM route. An additional six mares received IA administration of 240 mg tobramycin. Synovial fluid concentrations were 3056.47 ± 1310.89 μg/mL at 30 min after administration, and they persisted for up to 48 h with concentrations of 14.80 ± 7.47 μg/mL. Tobramycin IA resulted in a mild chemical synovitis as evidenced by an increase in synovial fluid cell count and total protein, but appeared to be safe for administration. Monte Carlo simulations suggest that tobramycin would be effective against bacteria with a minimum inhibitory concentration (MIC) of 2 μg/mL for IV administration and 1 μg/mL for IM administration based on C max :MIC of 10.}, number={6}, journal={JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS}, author={Newman, J. C. and Prange, T. and Jennings, S. and Barlow, B. M. and Davis, J. L.}, year={2013}, month={Dec}, pages={532–541} }
 @article{jennings_wise_nickeleit_maes_cianciolo_piero_law_kim_mccalla_breuhaus_et al._2013, title={Polyomavirus-Associated Nephritis in 2 Horses}, volume={50}, ISSN={0300-9858 1544-2217}, url={http://dx.doi.org/10.1177/0300985813476063}, DOI={10.1177/0300985813476063}, abstractNote={Polyomaviruses produce latent and asymptomatic infections in many species, but productive and lytic infections are rare. In immunocompromised humans, polyomaviruses can cause tubulointerstitial nephritis, demyelination, or meningoencephalitis in the central nervous system and interstitial pneumonia. This report describes 2 Standardbred horses with tubular necrosis and tubulointerstitial nephritis associated with productive equine polyomavirus infection that resembles BK polyomavirus nephropathy in immunocompromised humans.}, number={5}, journal={Veterinary Pathology}, publisher={SAGE Publications}, author={Jennings, S. H. and Wise, A. G. and Nickeleit, V. and Maes, R. K. and Cianciolo, R. E. and Piero, F. Del and Law, J. M. and Kim, Y. and McCalla, A. C. and Breuhaus, B. A. and et al.}, year={2013}, month={Feb}, pages={769–774} }
 @article{meuten_hickey_franklin_grossi_tobias_newman_jennings_correa_sannes_2012, title={WNT7B in fibroblastic foci of idiopathic pulmonary fibrosis}, volume={13}, ISSN={1465-9921}, url={http://dx.doi.org/10.1186/1465-9921-13-62}, DOI={10.1186/1465-9921-13-62}, abstractNote={Abstract Background Idiopathic pulmonary fibrosis (IPF) is a devastating interstitial pneumonia causing a loss of respiratory surface area due to a proliferative fibrotic response involving hyperplastic, hypertrophic, and metaplastic epithelium, cystic honeycomb change, septal expansion, and variable inflammation. Wnt (wingless) signaling glycoproteins are known to be involved in lung development and tissue repair, and are up-regulated in patients with IPF. Based on previous qRT-PCR data showing increased Wnt7B in lungs of IPF patients, a systematic, quantitative examination of its tissue site distribution was undertaken. Methods Tissue samples from the Lung Tissue Research Consortium (LTRC) of 39 patients diagnosed with mild to severe IPF/usual interstitial pneumonia (UIP) and 19 normal patients were examined for the immunolocalization of Wnt7B. Results In normal lung, moderate Wnt7B reactivity was confined to airway epithelium, smooth muscle of airways and vasculature, and macrophages. IPF lung showed strong Wnt7B reactivity in fibroblastic foci, dysplastic airway and alveolar epithelium, and in highly discrete subepithelial, basement membrane-associated regions. All reactive sites were sized and counted relative to specific microscopic regions. Those in the subepithelial sites were found in significantly greater numbers and larger relative area compared with the others. No reactive sites were present in normal patient controls. Conclusions The results demonstrate Wnt7B to be expressed at high concentrations in regions of active hyperplasia, metaplasia, and fibrotic change in IPF patients. In this context and its previously established biologic activities, Wnt7B would be expected to be of potential importance in the pathogenesis of IPF.}, number={1}, journal={Respiratory Research}, publisher={Springer Nature}, author={Meuten, Travis and Hickey, Ariel and Franklin, Katherine and Grossi, Brian and Tobias, Jeremy and Newman, Donna R and Jennings, Samuel H and Correa, Maria and Sannes, Philip L}, year={2012}, pages={62} }
 @article{hummel_grooters_davidson_jennings_nicklas_birkenheuer_2011, title={Successful management of gastrointestinal pythiosis in a dog using itraconazole, terbinafine, and mefenoxam}, volume={49}, ISSN={["1369-3786"]}, DOI={10.3109/13693786.2010.543705}, abstractNote={Medical therapy for pythiosis is hampered by a lack of efficacious drugs. The present report describes a case of canine gastrointestinal pythiosis in which lesions were resolved through the administration of itraconazole, terbinafine, and the agricultural fungicide mefenoxam. No substantial adverse effects occurred in association with administration of the latter compound. Additional studies are needed to evaluate the pharmacokinetics of mefenoxam and to further assess its tolerability and potential efficacy for the treatment of pythiosis in dogs.}, number={5}, journal={MEDICAL MYCOLOGY}, author={Hummel, James and Grooters, Amy and Davidson, Gigi and Jennings, Samuel and Nicklas, Jodi and Birkenheuer, Adam}, year={2011}, month={Jul}, pages={539–542} }