Works (36)

Updated: April 11th, 2023 10:13

2023 journal article

An inhaled bioadhesive hydrogel to shield non-human primates from SARS-CoV-2 infection

Nature Materials, 2.

By: X. Mei, J. Li, Z. Wang, D. Zhu, K. Huang, S. Hu, K. Popowski, K. Cheng

Sources: Web Of Science, ORCID, Crossref
Added: March 6, 2023

2022 article

Detachable Microneedle Patches Deliver Mesenchymal Stromal Cell Factor-Loaded Nanoparticles for Cardiac Repair

Hu, S., Zhu, D., Li, Z., & Cheng, K. (2022, September 23). ACS NANO, Vol. 9.

By: S. Hu, D. Zhu, Z. Li & K. Cheng

author keywords: mesenchymal stromal cell; secreted factors; microneedle patch; elastin-like peptide gel; hyaluronic acid gel; myocardial infarction; cardiac repair
Sources: Web Of Science, ORCID
Added: October 11, 2022

2022 journal article

Intrapericardial Exosome Therapy Dampens Cardiac Injury via Activating Foxo3

CIRCULATION RESEARCH, 131(10), E135–E150.

By: D. Zhu, S. Liu, K. Huang, Z. Wang, S. Hu, J. Li, Z. Li, K. Cheng

author keywords: exosomes; immunomodulation; mesesnchymal stem cell; myocardial infarction; regulatory T cell
Sources: Web Of Science, ORCID
Added: November 14, 2022

2022 journal article

Intrapericardial hydrogel injection generates high cell retention and augments therapeutic effects of mesenchymal stem cells in myocardial infarction

CHEMICAL ENGINEERING JOURNAL, 427.

By: J. Li, Y. Lv*, D. Zhu, X. Mei, K. Huang, X. Wang n, Z. Li, S. Zhang ...

author keywords: Mesenchymal stem cells; Hydrogel; Myocardial infarction; Intrapericardial; Intramyocardial
Sources: Web Of Science, ORCID
Added: January 3, 2022

2021 journal article

A Minimally Invasive Exosome Spray Repairs Heart after Myocardial Infarction

ACS NANO, 15(7), 11099–11111.

By: J. Yao*, K. Huang, D. Zhu, T. Chen*, Y. Jiang*, J. Zhang*, L. Mi*, H. Xuan* ...

author keywords: MSC; exosome; spray; myocardial infarction; heart repair
Sources: Web Of Science, ORCID
Added: August 23, 2021

2021 journal article

A fluid-powered refillable origami heart pouch for minimally invasive delivery of cell therapies in rats and pigs

MED, 2(11), 1253-+.

By: X. Mei, D. Zhu, J. Li, K. Huang, S. Hu, Z. Li, B. Abad n, K. Cheng

Sources: Web Of Science, ORCID
Added: November 3, 2021

2021 journal article

A stem cell-derived ovarian regenerative patch restores ovarian function and rescues fertility in rats with primary ovarian insufficiency

THERANOSTICS, 11(18), 8894–8908.

By: S. Zhang, D. Zhu, Z. Li, K. Huang, S. Hu, H. Lutz, M. Xie, X. Mei ...

author keywords: primary ovarian insufficiency; ovarian regenerative patch; regenerative medicine; mesenchymal stem cells; acellular therapy; fertility
Sources: Web Of Science, ORCID
Added: October 12, 2021

2021 review

All Roads Lead to Rome (the Heart): Cell Retention and Outcomes From Various Delivery Routes of Cell Therapy Products to the Heart

[Review of ]. JOURNAL OF THE AMERICAN HEART ASSOCIATION, 10(8).

By: J. Li, S. Hu, D. Zhu, K. Huang, X. Mei, B. Abad n, K. Cheng

author keywords: cardiac repair; cell delivery; intracoronary; intramyocardial; intrapericardial; intravenous; retention rate
Sources: Web Of Science, ORCID
Added: June 10, 2021

2021 journal article

Exosome-eluting stents for vascular healing after ischaemic injury

NATURE BIOMEDICAL ENGINEERING, 5(10), 1174–1188.

By: S. Hu, Z. Li, D. Shen, D. Zhu, K. Huang, T. Su, P. Dinh, J. Cores, K. Cheng

Sources: Web Of Science, ORCID
Added: April 6, 2021

2021 journal article

Extruded Mesenchymal Stem Cell Nanovesicles Are Equally Potent to Natural Extracellular Vesicles in Cardiac Repair

ACS APPLIED MATERIALS & INTERFACES, 13(47), 55767–55779.

By: X. Wang*, S. Hu, J. Li, D. Zhu, Z. Wang, J. Cores, K. Cheng, G. Liu*, K. Huang

author keywords: extrusion; nanovesicles; extracellular vesicles; mesenchymal stem cell; ischemia reperfusion injury
Sources: Web Of Science, ORCID
Added: February 21, 2022

2021 article

Generation and Manipulation of Exosomes

CARDIAC REGENERATION, Vol. 2158, pp. 295–305.

By: S. Hu, L. Qiao n & K. Cheng

author keywords: Exosome generation; Exosome manipulation; Myocardial infarction; Cardiac homing peptide; Platelet membrane; Intravenous injection
Sources: Web Of Science, ORCID
Added: August 30, 2021

2021 journal article

Injection of ROS-Responsive Hydrogel Loaded with Basic Fibroblast Growth Factor into the Pericardial Cavity for Heart Repair

ADVANCED FUNCTIONAL MATERIALS, 31(15).

By: Z. Li, D. Zhu, Q. Hui*, J. Bi*, B. Yu*, Z. Huang*, S. Hu, Z. Wang ...

author keywords: bFGF; heart repair; intrapericardial delivery; pericardial cavity; ROS responsive hydrogels
Sources: Web Of Science, ORCID
Added: February 22, 2021

2021 journal article

Platelet membrane and stem cell exosome hybrids enhance cellular uptake and targeting to heart injury

NANO TODAY, 39.

By: S. Hu, X. Wang n, Z. Li, D. Zhu, J. Cores, Z. Wang, J. Li, X. Mei ...

author keywords: Exosomes; Targeting; Myocardial infarction; Platelet membrane; Stem cells
Sources: Web Of Science, ORCID
Added: September 7, 2021

2021 journal article

Self-Propelled and Near-Infrared-Phototaxic Photosynthetic Bacteria as Photothermal Agents for Hypoxia-Targeted Cancer Therapy

ACS NANO, 15(1), 1100–1110.

By: P. Zheng*, M. Fan*, H. Liu*, Y. Zhang*, X. Dai*, H. Li*, X. Zhou*, S. Hu ...

Sources: Web Of Science, ORCID
Added: March 29, 2021

2020 journal article

Cardiac Stromal Cell Patch Integrated with Engineered Microvessels Improves Recovery from Myocardial Infarction in Rats and Pigs

ACS BIOMATERIALS SCIENCE & ENGINEERING, 6(11), 6309–6320.

By: T. Su, K. Huang, K. Mathews, V. Scharf, S. Hu, Z. Li, B. Frame*, J. Cores ...

author keywords: microfluidics; cardiac patch; cardiac stromal cells; myocardial infarction; porcine model
Sources: Web Of Science, ORCID
Added: December 11, 2020

2020 journal article

Dermal exosomes containing miR-218-5p promote hair regeneration by regulating beta-catenin signaling

SCIENCE ADVANCES, 6(30).

Sources: Web Of Science, ORCID
Added: August 10, 2020

2020 review

Engineering better stem cell therapies for treating heart diseases

[Review of ]. ANNALS OF TRANSLATIONAL MEDICINE, 8(8).

By: J. Li, S. Hu & K. Cheng

author keywords: Stem cell therapy; ischemic heart diseases; bioengineering strategies; clinical translation
Sources: Web Of Science, ORCID
Added: May 26, 2020

2020 review

Exosome therapeutics for lung regenerative medicine

[Review of ]. JOURNAL OF EXTRACELLULAR VESICLES, 9(1).

By: K. Popowski, H. Lutz, S. Hu, A. George, P. Dinh & K. Cheng

author keywords: Exosome; regenerative medicine; lung spheroid cell; stem cell
Sources: Web Of Science, ORCID
Added: July 20, 2020

2020 journal article

Inhalation of lung spheroid cell secretome and exosomes promotes lung repair in pulmonary fibrosis

NATURE COMMUNICATIONS, 11(1).

By: P. Dinh, D. Paudel n, H. Brochu, K. Popowski, M. Gracieux n, J. Cores, K. Huang, M. Hensley n ...

Sources: Web Of Science, ORCID
Added: March 23, 2020

2020 journal article

Light-triggered NO-releasing nanoparticles for treating mice with liver fibrosis

NANO RESEARCH, 13(8), 2197–2202.

By: H. Liang, Z. Li, Z. Ren*, Q. Jia*, L. Guo*, S. Li*, H. Zhang*, S. Hu ...

author keywords: liver fibrosis; nitric oxide (NO); hepatic stellate cells (HSC); nanoparticles; near infrared light (NIR)-controlled release
Sources: Web Of Science, ORCID
Added: June 29, 2020

2020 journal article

Targeted anti-IL-1 beta platelet microparticles for cardiac detoxing and repair

SCIENCE ADVANCES, 6(6).

By: Z. Li, S. Hu, K. Huang, T. Su, J. Cores & K. Cheng

Sources: Web Of Science, ORCID
Added: March 2, 2020

2020 journal article

Tumor cell-derived exosomes home to their cells of origin and can be used as Trojan horses to deliver cancer drugs

THERANOSTICS, 10(8), 3474–3487.

By: L. Qiao n, S. Hu, K. Huang, T. Su, Z. Li, A. Vandergriff, J. Cores, P. Dinh ...

author keywords: exosome; homing; integrin; doxorubicin; cancer therapy
Sources: Web Of Science, ORCID
Added: March 30, 2020

2019 journal article

Antibody-Armed Platelets for the Regenerative Targeting of Endogenous Stem Cells

NANO LETTERS, 19(3), 1883–1891.

By: D. Shen, Z. Li, S. Hu, K. Huang, T. Su, H. Liang, F. Liu n, K. Cheng

author keywords: Myocardium infarction; platelets; endogenous stem cells; antibodies
Sources: Web Of Science, ORCID
Added: April 2, 2019

2019 journal article

Bispecific Antibody Therapy for Effective Cardiac Repair through Redirection of Endogenous Stem Cells

ADVANCED THERAPEUTICS, 2(10).

By: K. Huang, Z. Li, T. Su, D. Shen, S. Hu & K. Cheng

author keywords: bispecific antibodies; immunotherapy; myocardial infarction; stem cells
Sources: Web Of Science, ORCID
Added: January 27, 2020

2019 review

Cell and biomaterial-based approaches to uterus regeneration

[Review of ]. REGENERATIVE BIOMATERIALS, 6(3), 141–148.

By: F. Liu*, S. Hu, S. Wang* & K. Cheng

author keywords: Asherman's syndrome; intrauterine adhesions; endometrium; stem cells
Sources: Web Of Science, ORCID
Added: September 16, 2019

2019 review

Chemical Engineering of Cell Therapy for Heart Diseases

[Review of ]. ACCOUNTS OF CHEMICAL RESEARCH, 52(6), 1687–1696.

By: Z. Li, S. Hu & K. Cheng

Sources: Web Of Science, ORCID
Added: July 15, 2019

2019 journal article

Excipient-free nanodispersion of 7-ethyl-10-hydroxycamptothecin exerts potent therapeutic effects against pancreatic cancer cell lines and patient-derived xenografts

CANCER LETTERS, 465, 36–44.

By: L. Zhang*, J. Zhou*, Y. Yan*, X. Zhou*, Q. Zhou*, R. Du*, S. Hu, W. Ge* ...

author keywords: Excipient-free nanodispersion; Pancreatic cancer; 7-Ethyl-10-hydroxycamptothecin (SN-38); Patient-derived xenograft (PDX); Irinotecan (CPT-11)
Sources: Web Of Science, ORCID
Added: November 11, 2019

2019 journal article

Hyaluronic Acid Hydrogel Integrated with Mesenchymal Stem Cell-Secretome to Treat Endometrial Injury in a Rat Model of Asherman's Syndrome

ADVANCED HEALTHCARE MATERIALS, 8(14).

By: F. Liu*, S. Hu, H. Yang n, Z. Li, K. Huang, T. Su, S. Wang*, K. Cheng

author keywords: Asherman's syndrome; endometrial injury; hyaluronic acid; mesenchymal stem cells; secretome
Sources: Web Of Science, ORCID
Added: August 12, 2019

2019 journal article

Needle-Free Injection of Exosomes Derived from Human Dermal Fibroblast Spheroids Ameliorates Skin Photoaging

ACS NANO, 13(10), 11273–11282.

By: S. Hu, Z. Li, J. Cores, K. Huang, T. Su, P. Dinh, K. Cheng

author keywords: needle free injection; dermal fibroblasts; spheroids; exosomes; skin aging; microRNA
Sources: Web Of Science, ORCID
Added: November 11, 2019

2019 journal article

Platelet-Inspired Nanocells for Targeted Heart Repair After Ischemia/Reperfusion Injury

ADVANCED FUNCTIONAL MATERIALS, 29(4).

By: T. Su, K. Huang, H. Ma*, H. Liang, P. Dinh, J. Chen, D. Shen, T. Allen n ...

author keywords: biomimetics; drug delivery; ischemic injury; platelets; stromal cell secretome
Sources: Web Of Science, ORCID
Added: February 4, 2019

2019 journal article

microRNA-21-5p dysregulation in exosomes derived from heart failure patients impairs regenerative potential

JOURNAL OF CLINICAL INVESTIGATION, 129(6), 2237–2250.

By: L. Qiao*, S. Hu, S. Liu*, H. Zhang*, H. Ma, K. Huang, Z. Li, T. Su ...

Sources: Web Of Science, ORCID
Added: June 24, 2019

2018 journal article

A New Era of Cardiac Cell Therapy: Opportunities and Challenges

Advanced Healthcare Materials, 8(2), 1801011.

By: K. Huang, S. Hu & K. Cheng

author keywords: cardiac patches; cell therapy; exosomes; injury targeting; microRNA; myocardial infarction; synthetic stem cells
Sources: Web Of Science, ORCID, Crossref
Added: February 11, 2019

2018 review

Body builder: from synthetic cells to engineered tissues

[Review of ]. CURRENT OPINION IN CELL BIOLOGY, 54, 37–42.

By: S. Hu, B. Ogle* & K. Cheng

Sources: Web Of Science, ORCID
Added: November 12, 2018

2018 review

Platelets and their biomimetics for regenerative medicine and cancer therapies

[Review of ]. JOURNAL OF MATERIALS CHEMISTRY B, 6(45), 7354–7365.

By: Z. Li, S. Hu & K. Cheng

Sources: Web Of Science, ORCID
Added: December 10, 2018

2018 journal article

Pretargeting and Bioorthogonal Click Chemistry-Mediated Endogenous Stem Cell Homing for Heart Repair

ACS NANO, 12(12), 12193–12200.

author keywords: pretargeting; bioorthogonal click chemistry; heart repair; endogenous stem cells; engineered antibodies
Sources: Web Of Science, ORCID
Added: January 14, 2019

2018 journal article

Targeting regenerative exosomes to myocardial infarction using cardiac homing peptide

THERANOSTICS, 8(7), 1869–1878.

By: A. Vandergriff, K. Huang, D. Shen*, S. Hu, M. Hensley, T. Caranasos*, L. Qian*, K. Cheng

author keywords: Targeting; exosomes; cardiac regeneration; heart disease; myocardial infarction
Sources: Web Of Science, ORCID
Added: August 6, 2018