Works (12)
Updated: July 5th, 2023 15:45
2015 journal article
Biaxial stress relaxation of semilunar heart valve leaflets during simulated collagen catabolism: Effects of collagenase concentration and equibiaxial strain state
Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine, 229(10), 721–731.
author keywords: Biomaterials; biomechanical testing or analysis; cardiovascular prostheses; tissue culture techniques
MeSH headings : Animals; Biomechanical Phenomena; Collagen / analysis; Collagen / metabolism; Collagenases / pharmacology; Female; Heart Valves / chemistry; Heart Valves / drug effects; Heart Valves / metabolism; Models, Biological; Swine
TL;DR:
Results in this in vitro study indicate that biaxial strain state is capable of affecting the susceptibility of valvular collagens to catabolism, providing a basis for further investigation of how such phenomena may manifest at different strain magnitudes or in vivo.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, Crossref, ORCID
Added: August 6, 2018
2014 conference paper
A biomechanical study of directional mechanical properties of porcine skin tissues
Proceedings of the ASME International Mechanical Engineering Congress and Exposition, 2013, vol 9.
Source: NC State University Libraries
Added: August 6, 2018
2014 journal article
Directional biomechanical properties of porcine skin tissue
Journal of Mechanics in Medicine and Biology, 14(5).
Source: NC State University Libraries
Added: August 6, 2018
2014 journal article
Prediction of matrix-to-cell stress transfer in heart valve tissues
Journal of Biological Physics, 41(1), 9–22.
author keywords: Finite element method; Heart valve tissues; Biomechanics; Stress analysis; Collagen fiber orientation; Tissue engineering
MeSH headings : Animals; Anisotropy; Collagen / metabolism; Elasticity; Extracellular Matrix / metabolism; Finite Element Analysis; Models, Cardiovascular; Pulmonary Valve / cytology; Pulmonary Valve / metabolism; Stress, Mechanical; Swine
TL;DR:
This is the first study reporting on the evolution of stress fields at both the tissue and cellular levels in valvular tissue, providing insight into how matrix-to-cell stress transfer may be influenced by the inhomogeneous collagen fiber architecture, tissue anisotropic material properties, and the cellular distribution within the leaflet tissue.
(via Semantic Scholar)
europepmc.org (repository)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, Crossref
Added: August 6, 2018
2014 conference paper
Tissue- and cell-level stress distributions of the heart valve tissue during diastole
Proceedings of the ASME International Mechanical Engineering Congress and Exposition, 2013, vol 9.
Source: NC State University Libraries
Added: August 6, 2018
2013 conference paper
A biomechanical study of directional mechanical properties of porcine skin tissues
ASME 2013 International Mechanical Engineering Congress & Exposition.
Source: NC State University Libraries
Added: August 6, 2018
2013 conference paper
Tissue- and cell-levels stress distribution of heart valve tissue during diastole
Proceedings of the ASME International Mechanical Engineering Congress and Exposition. Presented at the San Diego, CA.
Contributors: n & H. Huang n
Event: at San Diego, CA
TL;DR:
This is the first study reporting on the evolution of stress fields at both the tissue- and cellular-levels in valvular tissue, and thus contributes toward refining the collective understanding of valvULAR tissue micromechanics while providing a computational tool enabling further study of valVular cell-tissue interactions.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: NC State University Libraries, ORCID
Added: August 6, 2018
2013 journal article
Virtualisation of stress distribution in heart valve tissue
Computer Methods in Biomechanics and Biomedical Engineering, 17(15), 1696–1704.
Contributors: n & H. Huang n
author keywords: heart valve tissue; finite element method; collagen fibre architecture; stress analysis
MeSH headings : Anisotropy; Biomechanical Phenomena; Cell Nucleus / metabolism; Collagen / chemistry; Computer Simulation; Connective Tissue / physiopathology; Finite Element Analysis; Heart; Heart Valve Prosthesis; Heart Valves / physiology; Humans; Image Processing, Computer-Assisted / methods; Stress, Mechanical
TL;DR:
The results clearly reveal the roles of heterogeneously distributed collagen fibres in mitigating stress developments inside heart valve tissues and suggest that higher stress may be mediated by cells for biomechanical regulations.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018
2012 conference paper
A Biomechanical and Biochemical Synergy Study of Heart Valve Tissue
Proceedings of the ASME International Mechanical Engineering Congress and Exposition, 235–240.
Contributors: H. Huang n , B. Balhouse n & n
Event: at Houston TX
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: NC State University Libraries, ORCID
Added: August 6, 2018
2012 journal article
Application of simple biomechanical and biochemical tests to heart valve leaflets: Implications for heart valve characterization and tissue engineering
Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine, 226(11), 868–876.
Contributors: H. Huang n , B. Balhouse n & n
author keywords: Heart valves; real-time maps; mechanical property; collagen; microstructure
MeSH headings : Animals; Collagen / physiology; Equipment Design; Equipment Failure Analysis; Heart Valves / anatomy & histology; Heart Valves / physiology; Physical Stimulation / instrumentation; Physical Stimulation / methods; Swine; Tissue Engineering / instrumentation
TL;DR:
A simple biomechanical test with real-time displacement and strain mapping is reported, which provides displacement vectors and principal strain directions during the mechanical characterization of heart valve tissues, and potentially facilitates the development of tissue engineered heart valves.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018
2012 conference paper
Real-time strain mapping via biaxial stretching in heart valve tissues
IEEE Engineering in Medicine and Biology Society Conference Proceedings, 324–349.
Source: NC State University Libraries
Added: August 6, 2018
2012 conference paper
Virtual experiments of heart valve tissues
IEEE Engineering in Medicine and Biology Society Conference Proceedings, 324–349.
Source: NC State University Libraries
Added: August 6, 2018
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