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Works (43)
Updated: April 4th, 2024 21:05
2022 review
Recent progress in maize lethal necrosis disease: From pathogens to integrated pest management
[Review of ]. JOURNAL OF INTEGRATIVE AGRICULTURE, 21(12), 3445–3455.
author keywords: maize lethal necrosis disease; maize chlorotic mottle virus; integrated pest management
open access via doi.org (publisher)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
13. Climate Action
(Web of Science)
Source: Web Of Science
Added: January 30, 2023
2018 article
Plant Virus-Based Nanoparticles for the Delivery of Agronomic Compounds as a Suspension Concentrate
VIRUS-DERIVED NANOPARTICLES FOR ADVANCED TECHNOLOGIES: METHODS AND PROTOCOLS, Vol. 1776, pp. 203–214.
Contributors: R. Guenther n, n, C. Opperman n & T. Sit n
author keywords: Plant pathogenic nematode; Nematicide; Agrichemical; Plant viral nanoparticle; Nanoparticle formulation
MeSH headings : Ivermectin / analogs & derivatives; Ivermectin / chemistry; Nanoparticles / chemistry; Plant Viruses / chemistry; Tombusviridae / chemistry
TL;DR:
This work describes how to formulate a PVN loaded with the nematicide abamectin (Abm) beginning with the propagation of the virus through the formulation, deactivation, and characterization of the finished product.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: January 14, 2019
2017 journal article
Pharmacokinetics and efficacy of doxorubicin-loaded plant virus nanoparticles in preclinical models of cancer
NANOMEDICINE, 12(20), 2519–2532.
author keywords: efficacy; pharmacokinetics; plant virus nanoparticles
TL;DR:
The pharmacokinetics profiles of the PVNs showed fast plasma clearance, but more efficient tumor delivery as compared with other carrier-mediated agents.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2017 journal article
Soybean cyst nematode culture collections and field populations from North Carolina and Missouri reveal high incidences of infection by viruses
PLOS ONE, 12(1).
Contributors: C. Ruark n, S. Koenning n, E. Davis n, C. Opperman n, n, M. Mitchum *, T. Sit n
Ed(s): A. Rao
MeSH headings : Animals; DNA-Directed RNA Polymerases / metabolism; Gene Expression Regulation, Plant; Incidence; Life Cycle Stages / genetics; Missouri; North Carolina; Plant Diseases / parasitology; Plant Diseases / statistics & numerical data; Plant Diseases / virology; Plant Viruses / physiology; Real-Time Polymerase Chain Reaction; Soybeans / genetics; Soybeans / parasitology; Soybeans / virology; Species Specificity; Tylenchoidea / growth & development; Tylenchoidea / physiology; Virus Replication / physiology
TL;DR:
Viral titers within SCN greenhouse cultures were similar throughout juvenile development, and the presence of viral anti-genomic RNAs within egg, second-stage juvenile (J2), and pooled J4 stages suggests active viral replication within the nematode.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2015 journal article
Development of Abamectin Loaded Plant Virus Nanoparticles for Efficacious Plant Parasitic Nematode Control
ACS Applied Materials & Interfaces, 7(18), 9546–9553.
Contributors: J. Cao n, R. Guenther n, T. Sit n , n, C. Opperman n & J. Willoughby n
author keywords: red clover necrotic mosaic virus (RCNMV); plant virus nanoparticle (PVN); abamectin; soil mobility; crop protection
MeSH headings : Animals; Biological Availability; Caenorhabditis elegans / drug effects; Capsid / chemistry; Crops, Agricultural / drug effects; Crops, Agricultural / parasitology; Ivermectin / analogs & derivatives; Ivermectin / pharmacology; Solanum lycopersicum / drug effects; Solanum lycopersicum / parasitology; Nanoparticles / chemistry; Nematoda / drug effects; Pest Control, Biological; Plant Diseases / parasitology; Plant Viruses / chemistry; Soil; Suspensions; Tobacco / drug effects; Tobacco / parasitology; Tylenchoidea / drug effects
TL;DR:
Tomato seedlings treated with PVN(Abm) had healthier root growth and a reduction in root galling demonstrating the success of this delivery system for the increased efficacy of Abm to control nematode damage in crops.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Crossref, Web Of Science, ORCID
Added: August 6, 2018
2015 journal article
Development of abamectin loaded lignocellulosic matrices for the controlled release of nematicide for crop protection
CELLULOSE, 23(1), 673–687.
Contributors: J. Cao n, R. Guenther n, T. Sit n , n, C. Opperman n & J. Willoughby n
author keywords: Lignocellulosic matrix; Controlled release; Abamectin; Lignin; Crop protection
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2014 journal article
Loading and Release Mechanism of Red Clover Necrotic Mosaic Virus Derived Plant Viral Nanoparticles for Drug Delivery of Doxorubicin
SMALL, 10(24), 5126–5136.
Contributors: J. Cao n, R. Guenther n, T. Sit n , C. Opperman n, n & J. Willoughby n
MeSH headings : Antibiotics, Antineoplastic / administration & dosage; Antibiotics, Antineoplastic / pharmacokinetics; Capsid; Doxorubicin / administration & dosage; Doxorubicin / pharmacokinetics; Drug Carriers; Hydrogen-Ion Concentration; Nanoparticles; Tombusviridae / chemistry
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2013 journal article
New insight into the structure of RNA in red clover necrotic mosaic virus and the role of divalent cations revealed by small-angle neutron scattering
ARCHIVES OF VIROLOGY, 158(8), 1661–1669.
Contributors: S. Martin n, L. He *, F. Meilleur n , R. Guenther n, T. Sit n , n, W. Heller *
TL;DR:
Small-angle neutron scattering with contrast variation experiments were performed to better understand the organization of the RNA and conformational changes resulting from the removal of divalent cations in red clover necrotic mosaic virus and provide new insight into changes in the RNA packing.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
13. Climate Action
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2013 journal article
Polymeric Systems Incorporating Plant Viral Nanoparticles for Tailored Release of Therapeutics
ADVANCED HEALTHCARE MATERIALS, 2(7), 1001–1007.
author keywords: controlled release; drug delivery; nanofibers; plant viral nanoparticles; virus
MeSH headings : Antineoplastic Agents / administration & dosage; Doxorubicin / administration & dosage; Drug Carriers; Kinetics; Nanoparticles; Plant Viruses; Polymers
TL;DR:
Kinetic analysis results suggest a two‐phase release profile with the first phase following a hindered Fickian transport mechanism for the release of Dox for the polymer‐embedded PVNs and the nanofiber matrices that incorporate PVNs through the immersion processing method followed a pseudo‐first order kinetic transport mechanism.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2013 journal article
The red clover necrotic mosaic virus capsid protein N-terminal amino acids possess specific RNA binding activity and are required for stable virion assembly
VIRUS RESEARCH, 176(1-2), 107–118.
author keywords: RCNMV; Virus assembly; RNA-CP interactions; TABS; TA; Co-packaging
MeSH headings : Capsid Proteins / genetics; Capsid Proteins / metabolism; DNA Mutational Analysis; RNA-Binding Proteins / genetics; RNA-Binding Proteins / metabolism; Sequence Deletion; Tombusviridae / genetics; Tombusviridae / physiology; Virion / metabolism; Virus Assembly
TL;DR:
The N-terminal region of the CP is involved in both producing two virion populations due to its RNA binding properties and virion stability and was indispensable for stable virion formation and the region spanning CP residues 5-15 is required for systemic movement.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
13. Climate Action
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2012 journal article
The Red clover necrotic mosaic virus capsid protein N-terminal lysine-rich motif is a determinant of symptomatology and virion accumulation
MOLECULAR PLANT PATHOLOGY, 13(7), 744–754.
MeSH headings : Alanine / genetics; Amino Acid Motifs; Amino Acid Sequence; Amino Acid Substitution / genetics; Capsid Proteins / chemistry; Capsid Proteins / metabolism; Genome, Viral / genetics; Lysine / metabolism; Molecular Sequence Data; Mutation / genetics; Plant Diseases / virology; Plant Viral Movement Proteins / metabolism; RNA, Viral / metabolism; Sequence Alignment; Structure-Activity Relationship; Tobacco / virology; Tombusviridae / genetics; Tombusviridae / metabolism; Tombusviridae / physiology; Tombusviridae / ultrastructure; Virion / metabolism; Virion / ultrastructure
TL;DR:
Observations reaffirm the necessity of the N-terminal lysine-rich residues of the RCNMV CP for efficient virion accumulation and reveal additional roles for the CP in the modulation of host symptomatology, independent of its role in virion assembly and the rate of systemic viral movement in N. benthamiana.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
13. Climate Action
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2011 journal article
Pectobacterium carotovorum Elicits Plant Cell Death with DspE/F but the P. carotovorum DspE Does Not Suppress Callose or Induce Expression of Plant Genes Early in Plant-Microbe Interactions
MOLECULAR PLANT-MICROBE INTERACTIONS, 24(7), 773–786.
MeSH headings : Amino Acid Sequence; Bacterial Proteins / metabolism; Bacterial Secretion Systems / genetics; Bacterial Secretion Systems / physiology; Cell Death; Gene Expression Profiling; Gene Expression Regulation; Gene Expression Regulation, Plant; Glucans / metabolism; Host-Pathogen Interactions; Mitogen-Activated Protein Kinases / metabolism; Mutation; Pectobacterium carotovorum / genetics; Pectobacterium carotovorum / metabolism; Pectobacterium carotovorum / pathogenicity; Phenotype; Plant Diseases / genetics; Plant Diseases / microbiology; Plant Immunity; Plant Leaves / microbiology; Pseudomonas syringae / genetics; Pseudomonas syringae / pathogenicity; Sequence Alignment; Tobacco / cytology; Tobacco / genetics; Tobacco / metabolism; Tobacco / microbiology; Virulence Factors
TL;DR:
A model where Pectobacterium carotovorum uses the T3SS to induce plant cell death in order to promote leaf maceration rather than to suppress plant immunity is supported.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
13. Climate Action
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2010 journal article
Crystallization and preliminary X-ray diffraction analysis of red clover necrotic mosaic virus
ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS, 66(Pt 11), 1458–1462.
Contributors: S. Martin n, R. Guenther n, T. Sit n , P. Swartz n, F. Meilleur n , n, R. Rose n
author keywords: red clover necrotic mosaic virus; dianthoviruses; viruses
MeSH headings : Crystallization; Crystallography, X-Ray; Microscopy, Electron, Transmission; Tombusviridae / chemistry; Tombusviridae / ultrastructure; Virion / chemistry; Virion / ultrastructure
TL;DR:
Red clover necrotic mosaic virus is a species that belongs to the Tombusviridae family of plant viruses with a T = 3 icosahedral capsid and crystals diffracted to better than 4 Å resolution but were very radiation-sensitive, causing rapid decay of the high-resolution reflections.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 6, 2018
2010 journal article
The Red clover necrotic mosaic virus Capsid as a Multifunctional Cell Targeting Plant Viral Nanoparticle
BIOCONJUGATE CHEMISTRY, 22(1), 67–73.
MeSH headings : Amino Acid Sequence; Biological Availability; Biological Transport; Capsid / chemistry; Capsid / metabolism; Doxorubicin / chemistry; Doxorubicin / pharmacokinetics; Fluorescent Dyes / chemistry; HeLa Cells; Humans; Models, Molecular; Nanoparticles / chemistry; Peptides / chemistry; Peptides / metabolism; Plants / virology; Protein Conformation; Surface Properties; Tombusviridae
TL;DR:
It is shown that targeting peptides (less than 16 amino acids) can be conjugated to the capsid using the heterobifunctional chemical linker sulfosuccinimidyl-4-(N-maleimidomethyl)cyclohexane-1-carboxylate (Sulfo-SMCC).
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2009 review
Targeting cancer with 'smart bombs': equipping plant virus nanoparticles for a 'seek and destroy' mission
[Review of ]. NANOMEDICINE, 4(5), 575–588.
author keywords: biodegradable; capsid; chemotherapy; colloid; nanoparticle plant virus; receptor-mediated endocytosis; reticuloendothelial system
MeSH headings : Endocytosis; Humans; Liposomes; Micelles; Nanoparticles; Neoplasms / drug therapy; Plant Viruses
TL;DR:
The structural uniformity, cargo capacity, responsive behavior and ease of manufacturing of plant virus nanoparticles are unique properties that suggest they have a wider role to play in targeted therapy, and they are considered to have the most promise to address these complex phenomena.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2008 journal article
A versatile assay for the identification of RNA silencing suppressors based on complementation of viral movement
MOLECULAR PLANT-MICROBE INTERACTIONS, 21(7), 879–890.
Contributors: J. Powers n, T. Sit n , F. Qu *, T. Morris, K. Kim* & n
author keywords: IVIS lumina; p8; p9; pPZP212; VSR
MeSH headings : Agrobacterium tumefaciens / genetics; Arabidopsis / genetics; Arabidopsis / virology; Base Sequence; Capsid Proteins / genetics; Capsid Proteins / physiology; Carmovirus / genetics; Carmovirus / pathogenicity; Carmovirus / physiology; DNA, Viral / genetics; Genes, Reporter; Genetic Complementation Test; Green Fluorescent Proteins / genetics; Host-Pathogen Interactions / genetics; Movement; Plant Diseases / genetics; Plant Diseases / virology; RNA Interference; RNA, Viral / genetics; Recombinant Proteins / genetics; Suppression, Genetic; Tobacco / genetics; Tobacco / virology
TL;DR:
While the TCV-sGFP construct is primarily used as an infectious RNA transcript, it was also subcloned for direct expression from Agrobacterium tumefaciens for simple quantification of suppressor activity based on fluorescence levels in whole leaves, providing the flexibility to assay for suppressorActivity in either the cytoplasm or nucleus, depending on the construct employed.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
13. Climate Action
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2008 review
Nicotiana benthamiana: Its history and future as a model for plant-pathogen interactions
[Review of ]. MOLECULAR PLANT-MICROBE INTERACTIONS, 21(8), 1015–1026.
author keywords: AFLP; agroinfiltration; Arabidopsis; VIGS
MeSH headings : Amplified Fragment Length Polymorphism Analysis; Gene Silencing; Genetic Variation; Host-Pathogen Interactions; Plant Diseases / genetics; Plant Diseases / virology; Plant Viruses / physiology; Plants, Genetically Modified / genetics; Plants, Genetically Modified / virology; Tobacco / genetics; Tobacco / virology
TL;DR:
It is proposed that N. benthamiana is well situated to become a premier plant cell biology model, particularly for the virology community, who as a group were the first to recognize the potential of this unique Australian native.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018
2008 journal article
The Red clover necrotic mosaic virus RNA-2 encoded movement protein is a second suppressor of RNA silencing
VIROLOGY, 381(2), 277–286.
author keywords: TCV-sGFP; Red clover necrotic mosaic virus; RCNMV; Movement protein; MP; VSR; RNA silencing
MeSH headings : Carmovirus / genetics; Carmovirus / metabolism; Genetic Complementation Test; Green Fluorescent Proteins / metabolism; Plant Viral Movement Proteins / metabolism; RNA Interference; RNA, Viral / genetics; RNA, Viral / metabolism; Tombusviridae / genetics; Tombusviridae / metabolism
TL;DR:
A newly developed viral-based assay for the identification of silencing suppression activity was used to provide evidence for a second, mechanistically distinct method ofsilencing suppression provided for by the RCNMV movement protein (MP).
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
13. Climate Action
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2008 journal article
The Red clover necrotic mosaic virus origin of assembly is delimited to the RNA-2 trans-activator
VIROLOGY, 384(1), 169–178.
Contributors: V. Basnayake n, T. Sit n & n
author keywords: Red clover necrotic mosaic virus; Virion assembly; Origin of assembly; trans-activator; Dianthovirus; Tombusviridae
MeSH headings : Base Pairing; Capsid Proteins / genetics; Genome, Viral; Open Reading Frames; Promoter Regions, Genetic; RNA, Viral / genetics; Tombusviridae / genetics; Tombusviridae / physiology; Tombusvirus / genetics; Trans-Activators / genetics; Transcription, Genetic; Trifolium / virology; Viral Proteins / genetics; Virion / genetics; Virion / physiology; Virus Replication
TL;DR:
It is hypothesize that RNA-1 must be base-paired with RNA-2 at the TA to initiate co-packaging, and illustrates the critical importance of the multifunctional TA element as a key regulatory switch in the RCNMV life cycle.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
13. Climate Action
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2007 journal article
Encapsidation of nanoparticles by Red Clover Necrotic Mosaic Virus
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 129(36), 11111–11117.
MeSH headings : Biocompatible Materials; Capsid / physiology; Capsid Proteins / genetics; Capsid Proteins / metabolism; Cobalt / chemistry; Ferric Compounds / chemistry; Gold / chemistry; Nanoparticles / chemistry; Nanotechnology; Quantum Dots; Tombusviridae / physiology; Virus Assembly
TL;DR:
Covalent linkage of the OAS to nanoparticles directs RNA-dependent encapsidation and demonstrates that foreign cargo can be packaged into RCNMV virions.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2007 journal article
Infusion of dye molecules into Red clover necrotic mosaic virus
CHEMICAL COMMUNICATIONS, (1), 88–90.
MeSH headings : Capsid Proteins / chemistry; Capsid Proteins / metabolism; Coloring Agents / analysis; Coloring Agents / metabolism; Doxorubicin / metabolism; Microscopy, Electron, Transmission; Tombusviridae / chemistry; Tombusviridae / metabolism; Tombusviridae / ultrastructure
TL;DR:
The Red clover necrotic mosaic virus capsid is utilized to package and release molecules through reversible depletion and re-addition of divalent cations.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2006 journal article
Controlled encapsidation of gold nanoparticles by a viral protein shell
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 128(14), 4502–4503.
MeSH headings : Capsid Proteins / chemistry; Capsid Proteins / genetics; DNA, Viral / chemistry; DNA, Viral / genetics; Gold / chemistry; Metal Nanoparticles / chemistry; Microscopy, Electron, Transmission; RNA, Viral / chemistry; RNA, Viral / genetics; Tombusviridae / chemistry; Tombusviridae / genetics
TL;DR:
Covalent linkage of the OAS to Au functions as a trigger for specific encapsidation and demonstrates that foreign cargo can be packaged into Red clover necrotic mosaic virus virions.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2006 journal article
Proximal cavity, distal histidine, and substrate hydrogen-bonding mutations modulate the activity of Amphitrite ornata dehaloperoxidase
BIOCHEMISTRY, 45(30), 9085–9094.
Contributors: S. Franzen n , J. Belyea n, L. Gilvey n, M. Davis n, C. Chaudhary n, T. Sit n , n
MeSH headings : Animals; Binding Sites / genetics; Hemoglobins; Histidine / chemistry; Histidine / genetics; Hydrogen Bonding; Mutagenesis, Site-Directed; Peroxidases / chemistry; Peroxidases / genetics; Peroxidases / metabolism; Phenylalanine / genetics; Polychaeta / enzymology; Polychaeta / genetics; Substrate Specificity / genetics; Tyrosine / genetics; Valine / genetics
TL;DR:
The role of tyrosine 38 (Y38), which hydrogen bonds to the hydroxyl group of the substrate, was probed and it was suggested that abolishing this hydrogen bond may open a pathway for the escape of the one-electron product, the phenoxy radical leading to polymeric products.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
14. Life Below Water
(OpenAlex)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 6, 2018
2006 journal article
Removal of divalent cations induces structural transitions in Red clover necrotic mosaic virus, revealing a potential mechanism for RNA release
JOURNAL OF VIROLOGY, 80(21), 10395–10406.
Contributors: M. Sherman n, R. Guenther n, F. Tama *, T. Sit n , C. Brooks *, A. Mikhailov*, E. Orlova *, T. Baker n, n
MeSH headings : Amino Acid Sequence; Calcium / metabolism; Capsid / metabolism; Capsid / ultrastructure; Capsid Proteins / genetics; Capsid Proteins / metabolism; Capsid Proteins / ultrastructure; Cations, Divalent / metabolism; Cryoelectron Microscopy; Image Processing, Computer-Assisted; Magnesium / metabolism; Models, Molecular; Molecular Sequence Data; Multiprotein Complexes; RNA, Viral / genetics; RNA, Viral / metabolism; Sequence Homology, Amino Acid; Species Specificity; Static Electricity; Tombusviridae / genetics; Tombusviridae / metabolism; Tombusviridae / ultrastructure
TL;DR:
Results indicate that divalent cations play a central role in capsid dynamics and suggest a mechanism for the release of viral RNA in low-divalent-cation environments such as those found within the cytoplasm of a cell.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2005 journal article
Cell wall localization of Red clover necrotic mosaic virus movement protein is required for cell-to-cell movement
VIROLOGY, 333(1), 10–21.
Contributors: D. Tremblay n, A. Vaewhongs n, K. Turner n, T. Sit n & n
author keywords: RCNMV movement protein; plasmodesmata; GFP; intracellular localization; viral movement; confocal microscopy
MeSH headings : Amino Acid Sequence; Cell Wall / physiology; Cell Wall / virology; Mosaic Viruses / genetics; Mosaic Viruses / physiology; Mutation; Plant Diseases / virology; Plant Viral Movement Proteins; Plants, Genetically Modified; Protein Transport; RNA, Viral; Recombinant Fusion Proteins / metabolism; Tobacco / ultrastructure; Tobacco / virology; Viral Proteins / metabolism; Viral Proteins / physiology
TL;DR:
The data suggest the presence of distinct domains in the MP for virus movement, complementarity, and intracellular localization and support a model of MP interacting cooperatively with itself to bind viral RNA, localize to and modify plasmodesmata and effect virus movement.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
13. Climate Action
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2005 journal article
Enzyme function of the globin dehaloperoxidase from Amphitrite ornata is activated by substrate binding
BIOCHEMISTRY, 44(48), 15637–15644.
Contributors: J. Belyea n, L. Gilvey n, M. Davis n, M. Godek n, T. Sit n , n, S. Franzen n
MeSH headings : Animals; Cloning, Molecular; Enzyme Activation; Escherichia coli / enzymology; Escherichia coli / genetics; Globins / metabolism; Hemoglobins; Hydrogen Peroxide / metabolism; Peroxidases / antagonists & inhibitors; Peroxidases / genetics; Peroxidases / metabolism; Phenols / metabolism; Polychaeta / enzymology; Protein Binding; Recombinant Proteins / isolation & purification; Recombinant Proteins / metabolism
TL;DR:
The present study shows that, unlike other known peroxidases, DHP activity requires the addition of substrate, TBP, prior to the cosubstrate, peroxide.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
6. Clean Water and Sanitation
(OpenAlex)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 6, 2018
2005 journal article
Identification and characterization of cowpea aphid-borne mosaic virus as the second virus from mixed-infected Crotalaria juncea plants in Nigeria
Zeitschrift Fur Pflanzenkrankheiten Und Pflanzenschutz, 112(3), 222–228.
Source: NC State University Libraries
Added: August 6, 2018
2005 journal article
The genomic RNA packaging scheme of Red clover necrotic mosaic virus
VIROLOGY, 345(2), 532–539.
Contributors: V. Basnayake n, T. Sit n & n
author keywords: RCNMV; virions; UV crosslinking; heating; co-packaging; genome; multipartite; heterodimer; homodimer
MeSH headings : Dimerization; Genome, Viral; Plant Diseases / virology; Plant Viruses / genetics; Plant Viruses / metabolism; RNA, Viral / metabolism; Tobacco / virology; Tombusviridae / genetics; Tombusviridae / metabolism; Trifolium / virology; Virion / metabolism; Virus Assembly
TL;DR:
Results indicate that RCNMV virions consist of two distinct populations: (i) virions containing both genomic RNAs; and (ii) virion with multiple copies of RNA-2.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
13. Climate Action
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2004 journal article
A Sobemovirus coat protein gene complements long-distance movement of a coat protein-null Dianthovirus
VIROLOGY, 330(1), 186–195.
author keywords: long-distance movement; complementation; coat protein; Dianthovirus; Sobemovirus; arabidopsis; chimera
MeSH headings : Arabidopsis / virology; Base Sequence; Brassica napus / virology; Capsid Proteins / genetics; DNA Primers; Genome, Viral; Molecular Sequence Data; Nucleic Acid Conformation; RNA Viruses / classification; RNA Viruses / genetics; RNA, Viral / chemistry; RNA, Viral / genetics; Tombusviridae / classification; Tombusviridae / genetics
TL;DR:
It is shown that the TRoV CP gene is capable of facilitating the vascular movement of a Dianthovirus and described the unprecedented complementation of systemic movement function by intergenic complete substitution of a plant virus CP gene.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018
2004 journal article
Red clover necrotic mosaic virus replication proteins accumulate at the endoplasmic reticulum
VIROLOGY, 320(2), 276–290.
Contributors: K. Turner n, T. Sit n , A. Callaway n, N. Allen n & n
author keywords: RCNMV; polymerase; green fluorescent protein; endoplasmic reticulum; co-localization; Tombusviridae; confocal microscopy
MeSH headings : Endoplasmic Reticulum / metabolism; Endoplasmic Reticulum / virology; Green Fluorescent Proteins; Luminescent Proteins / genetics; Luminescent Proteins / metabolism; Microfilament Proteins / genetics; Microfilament Proteins / metabolism; Microscopy, Confocal; Muscle Proteins; Plants, Genetically Modified; Recombinant Fusion Proteins / genetics; Recombinant Fusion Proteins / metabolism; Tobacco / virology; Tombusviridae / genetics; Tombusviridae / metabolism; Tombusviridae / pathogenicity; Trifolium / virology; Viral Proteins / genetics; Viral Proteins / metabolism; Virus Replication
TL;DR:
Independent accumulation in, and perturbation of, the ER suggests that p27 and p88 function together in the replication complex, the first report of a member of the Tombusviridae replicating in association with the ER.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2004 journal article
Structural characterization of an intermolecular RNA-RNA interaction involved in the transcription regulation element of a bipartite plant virus
NUCLEIC ACIDS RESEARCH, 32(9), 2819–2828.
Contributors: R. Guenther*, T. Sit , H. Gracz, M. Dolan, H. Townsend, G. Liu, W. Newman, P. Agris,
MeSH headings : Base Pairing; Base Sequence; Computer Simulation; Gene Expression Regulation, Viral; Macromolecular Substances; Models, Molecular; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Nucleic Acid Conformation; Promoter Regions, Genetic; RNA, Viral / chemistry; RNA, Viral / metabolism; Regulatory Sequences, Ribonucleic Acid; Tombusviridae / genetics; Transcription, Genetic
TL;DR:
The RCNMV TA structural model is similar to those for the Simian retrovirus frameshifting element and the Human immunodeficiency virus-1 dimerization kissing hairpins, suggesting a conservation of form and function.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2004 journal article
The Structure of Red Clover Necrostic Mosaic Dianthovirus at 10 Å Resolution
Microscopy and Microanalysis, 10(S02), 1486–1487.
TL;DR:
Extended abstract of a paper presented at Microscopy and Microanalysis 2004 in Savannah, Georgia, USA, August 1–5, 2004.
(via Semantic Scholar)
Source: Crossref
Added: August 28, 2020
2002 journal article
The Potato virus Y (MNR)-N-S Nlb-replicase is the elicitor of a veinal necrosis-hypersensitive response in root knot nematode resistant tobacco
MOLECULAR PLANT PATHOLOGY, 3(3), 145–152.
TL;DR:
The PVY M(s)N(r) NIb-replicase protein was found to induce a hypersensitive response 10 days post inoculation in nematode resistant tobacco, the first report of a Potyvirus replicase functioning as an avirulence factor.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
3. Good Health and Well-being
(OpenAlex)
13. Climate Action
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2001 journal article
A single amino acid mutation in the Carnation ringspot virus capsid protein allows virion formation but prevents systemic infection
JOURNAL OF VIROLOGY, 75(19), 9538–9542.
Contributors: T. Sit n , P. Haikal n, A. Callaway n & n
MeSH headings : Amino Acid Sequence; Amino Acid Substitution; Capsid / genetics; Molecular Sequence Data; Plant Viruses / physiology; Plants / virology; Point Mutation; Virion / physiology; Virulence / genetics; Virus Assembly / genetics
TL;DR:
Results provide additional support for the theory that virion formation is necessary but not sufficient for systemic movement with the dianthoviruses.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
13. Climate Action
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2001 review
The multifunctional capsid proteins of plant RNA viruses
[Review of ]. ANNUAL REVIEW OF PHYTOPATHOLOGY, 39(1), 419-+.
Contributors: A. Callaway n, D. Giesman-Cookmeyer n, E. Gillock n, T. Sit n & n
author keywords: evolution; movement; transmission; resistance; host-factors; biotechnology
MeSH headings : Biotechnology; Capsid / genetics; Capsid / physiology; Genome, Viral; Phylogeny; Plant Diseases / virology; Plant Viruses / genetics; Plant Viruses / physiology; RNA Viruses / genetics; RNA Viruses / physiology; RNA, Viral / genetics; RNA, Viral / physiology
TL;DR:
This article summarizes studies of viral coat (capsid) proteins (CPs) of RNA plant viruses and considers the evolution of viral CPs and their multitude of interactions with factors encoded by the virus, host plant, or viral vector that influence the infection and epidemiological facets of plant disease.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
3. Good Health and Well-being
(OpenAlex)
13. Climate Action
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
1998 journal article
Mutations in viral movement protein alter systemic infection and identify an intercellular barrier to entry into the phloem long-distance transport system
VIROLOGY, 245(1), 75–89.
MeSH headings : Biological Transport; Microscopy, Electron; Mosaic Viruses / physiology; Mosaic Viruses / ultrastructure; Mutation; Plants / ultrastructure; Plants / virology; Viral Proteins; Virus Replication / genetics
TL;DR:
The roles of the RCNMV MP in cell-to-cell movement and in long-distance transport appear to be genetically distinct, and the mechanism by which RCN MV enters the phloem to establish a systemic infection is discussed.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018
1998 journal article
RNA-mediated trans-activation of transcription from a viral RNA
SCIENCE, 281(5378), 829–832.
Contributors: T. Sit n , A. Vaewhongs n & n
MeSH headings : Base Composition; Base Sequence; DNA, Complementary; Gene Expression; Genes, Reporter; Green Fluorescent Proteins; Luminescent Proteins / genetics; Models, Genetic; Molecular Sequence Data; Mosaic Viruses / genetics; Mutation; Nucleic Acid Conformation; Promoter Regions, Genetic; RNA, Double-Stranded / genetics; RNA, Double-Stranded / metabolism; RNA, Messenger / biosynthesis; RNA, Messenger / genetics; RNA, Viral / biosynthesis; RNA, Viral / chemistry; RNA, Viral / genetics; Sequence Alignment; Transcriptional Activation
TL;DR:
A model is proposed in which direct binding of RNA-2 to RNA-1 trans-activates sgRNA synthesis, which is unusual among RNA viruses, which typically rely on protein regulators.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
13. Climate Action
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
1998 journal article
Selection for resistance and tolerance to oat mosaic virus and oat golden stripe virus in hexaploid oats
PLANT DISEASE, 82(4), 423–427.
author keywords: multiple regression model; soil-borne virus
TL;DR:
The results suggest that selection of lines with symptomatic tissue of 10% or less, or selection of tolerant lines, is needed for breeding progress.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
13. Climate Action
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
1998 journal article
Sequence element required for efficient -1 ribosomal frameshifting in red clover necrotic mosaic dianthovirus
VIROLOGY, 250(1), 50–59.
MeSH headings : Amino Acid Sequence; Base Pairing; Base Sequence; Cells, Cultured; Fabaceae / virology; Frameshifting, Ribosomal / genetics; Molecular Sequence Data; Mosaic Viruses / genetics; Mutagenesis, Site-Directed; Nucleic Acid Conformation; Plants, Medicinal; Plants, Toxic; Protoplasts / virology; RNA, Messenger / chemistry; RNA, Viral / chemistry; RNA, Viral / genetics; Recombinant Fusion Proteins; Tobacco / virology
TL;DR:
The essential role of a predicted secondary structure that does not involve a pseudoknot in the expression of the RCNMV polymerase by ribosomal frameshifting is demonstrated.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
13. Climate Action
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
1998 patent
Trans-activation of transcription from viral RNA
Washington, DC: U.S. Patent and Trademark Office.
Source: NC State University Libraries
Added: August 6, 2018
1997 journal article
Characteristics of beet soilborne mosaic virus, a furo-like virus infecting sugar beet
PLANT DISEASE, 81(9), 1070–1076.
TL;DR:
Results of serological, hybridization, and virulence experiments indicate that BSBMV is distinct from BNYVV, but host range, capsid size, and the number, size and polyadenylation of its RNAs indicate thatBSBMV more closely resembles B NYVV than it does other members of the genus Furovirus.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018
1991 journal article
CHARACTERIZATION OF MAIZE CHLOROTIC MOTTLE VIRUS
PHYTOPATHOLOGY, 81(8), 819–823.
TL;DR:
Maize chlorotic mottle virus infection produces two discrete double-Stranded RNA species in infected maize plants, corresponding to single-stranded RNAs of 4.4 and 1.1 kb, and no genome-linked protein was detected.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
13. Climate Action
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
1991 article
IDENTIFICATION OF THE MAIZE CHLOROTIC MOTTLE VIRUS CAPSID PROTEIN CISTRON AND CHARACTERIZATION OF ITS SUBGENOMIC MESSENGER-RNA
LOMMEL, S. A., KENDALL, T. L., XIONG, Z., & NUTTER, R. C. (1991, March). VIROLOGY, Vol. 181, pp. 382–385.
MeSH headings : Base Sequence; Capsid / genetics; Genes, Viral; Molecular Sequence Data; Oligonucleotide Probes; Open Reading Frames; Plant Viruses / genetics; Plasmids; RNA, Messenger / genetics; RNA, Viral / genetics; RNA, Viral / isolation & purification; Sequence Homology, Nucleic Acid; Viral Structural Proteins / genetics; Zea mays
TL;DR:
Data suggest that the MCMV capsid protein is expressed from a subgenomic RNA in vivo, and that the 25-kDa capsidprotein is encoded by the 3'-proximal open reading frame in theMCMV genome.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
13. Climate Action
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
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