Sydney Lynne Shuping

Animal Science

Works (6)

Updated: April 5th, 2024 13:23

2023 article

Role of Kndy and Arcuate Kiss1r-Containing Neurons in the Preovulatory Luteinizing Hormone Surge and Puberty Onset of Female sheep

Griesgraber, M. J., Onslow, K. M., Shuping, S., Bowdridge, E., Hardy, S., Aerts, E., … Goodman, R. (2023, November 6). JOURNAL OF ANIMAL SCIENCE, Vol. 101, pp. 235–236.

By: M. Griesgraber*, K. Onslow*, S. Shuping n, E. Bowdridge *, S. Hardy*, E. Aerts*, L. Coolen*, C. Nestor n  ...

author keywords: kisspeptin; luteinizing hormone; sheep
TL;DR: It is proposed that in ewes, KNDy neurons contribute to, but are not required for, the LH surge, and the role of ARC Kiss1r neurons in ovine puberty is assessed using a similar approach. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: December 11, 2023

2023 article

The effect of NK3-Saporin injection within the arcuate nucleus on puberty, the LH surge, and the response to Senktide in female sheep

Aerts, E. G., Griesgraber, M. J., Shuping, S. L., Bowdridge, E. C., Hardy, S. L., Goodman, R. L., … Hileman, S. M. (2023, October 31). BIOLOGY OF REPRODUCTION, Vol. 10.

By: E. Aerts, M. Griesgraber, S. Shuping n, E. Bowdridge, S. Hardy, R. Goodman *, C. Nestor n , S. Hileman*

author keywords: Puberty; KNDy; Luteinizing Hormone; sheep; female; NK3R
TL;DR: Results show that KNDy cells are necessary for timely puberty onset and for full expresson of the LH surge, and the occurrence of LH pulses in NK3-SAP treated ewes may indicate a recovery from an apulsatile state. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: October 31, 2023

2022 article

The impact of undernutrition on KNDy (kisspeptin/neurokinin B/dynorphin) neurons in female lambs

Harlow, K. L., Griesgraber, M. J., Seman, A. D., Shuping, S. L., Sommer, J. R., Griffith, E. H., … Nestor, C. C. (2022, May 17). JOURNAL OF NEUROENDOCRINOLOGY, Vol. 34.

By: K. Harlow n , M. Griesgraber*, A. Seman*, S. Shuping n, J. Sommer n, E. Griffith n, S. Hileman*, C. Nestor n 

author keywords: dynorphin; kisspeptin; LH; neurokinin B; undernutrition; xxxx; fx1
MeSH headings : Animals; Arcuate Nucleus of Hypothalamus / metabolism; Body Weight; Dynorphins / metabolism; Female; Gonadotropin-Releasing Hormone / metabolism; Kisspeptins / metabolism; Malnutrition / metabolism; Neurokinin B / metabolism; Neurons / metabolism; RNA, Messenger / metabolism; Sheep
TL;DR: The idea that KNDy neurons are important for regulating reproduction during undernutrition in female sheep is supported, as lower mRNA abundance for kisspeptin within K NDy neurons of FR lambs compared to controls with no significant change in mRNA for NKB or dynorphin is observed. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: April 14, 2022

2021 journal article

Evidence That Agouti-Related Peptide May Directly Regulate Kisspeptin Neurons in Male Sheep

METABOLITES, 11(3).

By: C. Merkley, S. Shuping, J. Sommer & C. Nestor 

Sources: Web Of Science, NC State University Libraries
Added: April 5, 2021

2021 journal article

Evidence that pubertal status impacts kisspeptin/neurokinin B/dynorphin neurons in the gilt(dagger)

BIOLOGY OF REPRODUCTION, 105(6), 1533–1544.

By: K. Harlow n , A. Renwick n, S. Shuping n, J. Sommer n, C. Lents*, M. Knauer n, C. Nestor n 

author keywords: kisspeptin; NKB; dynorphin; swine; puberty
MeSH headings : Animals; Arcuate Nucleus of Hypothalamus / metabolism; Dynorphins / metabolism; Female; Kisspeptins / metabolism; Neurokinin B / metabolism; Neurons / physiology; Sexual Maturation; Sus scrofa / physiology
TL;DR: The degree to which KNDy neurons exist in the gilt is characterized for the first time, and the impact of pubertal status on kisspeptin, neurokinin B, and dynorphin in the arcuate nucleus of gilts is examined. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: April 18, 2022

2020 article

Effects of genetic selection for early puberty on the hypothalamic-pituitary-ovarian axis in gilts

Harlow, K. L., Renwick, A., Shuping, S., Sommer, J., Knauer, M., & Nestor, C. (2020, November). JOURNAL OF ANIMAL SCIENCE, Vol. 98, pp. 212–212.

By: K. Harlow n , A. Renwick n, S. Shuping n, J. Sommer n, M. Knauer n & C. Nestor n 

author keywords: puberty; gilt; neuroendocrine
TL;DR: It is concluded that gilts genetically selected for early puberty do so via changes within the hypothalamus that increase gonadotropin secretion and, in turn, stimulate ovarian growth to ultimately advance the timing of puberty onset. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: February 8, 2021

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