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Works (7)
Updated: November 8th, 2024 05:01
2024 article
Development of KISS1 knockout pigs is characterized by hypogonadotropic hypogonadism, normal growth, and reduced skatole
Ahern, D. F., Martins, K., Florez, J. M., Ross, C. E., Huisman, A., Cushman, R. A., … Lents, C. A. (2024, October 14). BIOLOGY OF REPRODUCTION.
author keywords: kisspeptin; knockout; swine; skatole; luteinizing hormone; follicle-stimulating hormone; testosterone; development; reproduction
open access via academic.oup.com (publisher PDF)
Source: Web Of Science
Added: November 4, 2024
2023 article
Role of Kndy and Arcuate Kiss1r-Containing Neurons in the Preovulatory Luteinizing Hormone Surge and Puberty Onset of Female sheep
Griesgraber, M. J., Onslow, K. M., Shuping, S., Bowdridge, E., Hardy, S., Aerts, E., … Goodman, R. (2023, November 6). JOURNAL OF ANIMAL SCIENCE, Vol. 101, pp. 235–236.
author keywords: kisspeptin; luteinizing hormone; sheep
TL;DR:
It is proposed that in ewes, KNDy neurons contribute to, but are not required for, the LH surge, and the role of ARC Kiss1r neurons in ovine puberty is assessed using a similar approach.
(via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: December 11, 2023
2023 article
The effect of NK3-Saporin injection within the arcuate nucleus on puberty, the LH surge, and the response to Senktide in female sheep
Aerts, E. G., Griesgraber, M. J., Shuping, S. L., Bowdridge, E. C., Hardy, S. L., Goodman, R. L., … Hileman, S. M. (2023, October 31). BIOLOGY OF REPRODUCTION, Vol. 10.
author keywords: Puberty; KNDy; Luteinizing Hormone; sheep; female; NK3R
TL;DR:
Results show that KNDy cells are necessary for timely puberty onset and for full expresson of the LH surge, and the occurrence of LH pulses in NK3-SAP treated ewes may indicate a recovery from an apulsatile state.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: October 31, 2023
2022 article
The impact of undernutrition on KNDy (kisspeptin/neurokinin B/dynorphin) neurons in female lambs
Harlow, K. L., Griesgraber, M. J., Seman, A. D., Shuping, S. L., Sommer, J. R., Griffith, E. H., … Nestor, C. C. (2022, May 17). JOURNAL OF NEUROENDOCRINOLOGY, Vol. 34.
author keywords: dynorphin; kisspeptin; LH; neurokinin B; undernutrition; xxxx; fx1
MeSH headings : Animals; Arcuate Nucleus of Hypothalamus / metabolism; Body Weight; Dynorphins / metabolism; Female; Gonadotropin-Releasing Hormone / metabolism; Kisspeptins / metabolism; Malnutrition / metabolism; Neurokinin B / metabolism; Neurons / metabolism; RNA, Messenger / metabolism; Sheep
TL;DR:
The idea that KNDy neurons are important for regulating reproduction during undernutrition in female sheep is supported, as lower mRNA abundance for kisspeptin within K NDy neurons of FR lambs compared to controls with no significant change in mRNA for NKB or dynorphin is observed.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: April 14, 2022
2021 journal article
Evidence That Agouti-Related Peptide May Directly Regulate Kisspeptin Neurons in Male Sheep
METABOLITES, 11(3).
Sources: Web Of Science, NC State University Libraries
Added: April 5, 2021
2021 journal article
Evidence that pubertal status impacts kisspeptin/neurokinin B/dynorphin neurons in the gilt(dagger)
BIOLOGY OF REPRODUCTION, 105(6), 1533–1544.
author keywords: kisspeptin; NKB; dynorphin; swine; puberty
MeSH headings : Animals; Arcuate Nucleus of Hypothalamus / metabolism; Dynorphins / metabolism; Female; Kisspeptins / metabolism; Neurokinin B / metabolism; Neurons / physiology; Sexual Maturation; Sus scrofa / physiology
TL;DR:
The degree to which KNDy neurons exist in the gilt is characterized for the first time, and the impact of pubertal status on kisspeptin, neurokinin B, and dynorphin in the arcuate nucleus of gilts is examined.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: April 18, 2022
2020 article
Effects of genetic selection for early puberty on the hypothalamic-pituitary-ovarian axis in gilts
Harlow, K. L., Renwick, A., Shuping, S., Sommer, J., Knauer, M., & Nestor, C. (2020, November). JOURNAL OF ANIMAL SCIENCE, Vol. 98, pp. 212–212.
author keywords: puberty; gilt; neuroendocrine
TL;DR:
It is concluded that gilts genetically selected for early puberty do so via changes within the hypothalamus that increase gonadotropin secretion and, in turn, stimulate ovarian growth to ultimately advance the timing of puberty onset.
(via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: February 8, 2021
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