Works (120)

Updated: April 5th, 2024 10:24

2024 article

ACVIM consensus statement on diagnosis and management of urinary incontinence in dogs

Kendall, A., Byron, J. K., Westropp, J. L., Coates, J. R., Vaden, S., Adin, C., … Berent, A. (2024, January 13). JOURNAL OF VETERINARY INTERNAL MEDICINE, Vol. 1.

By: A. Kendall n, J. Byron*, J. Westropp*, J. Coates*, S. Vaden n, C. Adin*, G. Oetelaar, J. Bartges* ...

author keywords: canine; incontinence; urinary
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: February 12, 2024

2023 article

Adeno-associated virus-vectored erythropoietin gene therapy for anemia in cats with chronic kidney disease

Vaden, S. L., Kendall, A. R., Foster, J. D., New, H. L., Eagleson, J. S., May, J. L., … Wilson, J. M. (2023, October 17). JOURNAL OF VETERINARY INTERNAL MEDICINE.

By: S. Vaden n, A. Kendall n, J. Foster, H. New*, J. Eagleson, J. May, A. Traas, M. Wilson ...

author keywords: AAV; cats; red blood cells; renal disease
TL;DR: Results of this study suggest that SB‐001 therapy represents a suitable single injection treatment that can address nonregenerative anemia in cats with CKD. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: Web Of Science
Added: October 30, 2023

2023 article

Differentiation of stable kidney function versus progressive dysfunction in dogs

Cowgill, L. D., Segev, G., Vaden, S., Ross, S., Dufayet, C., Cohn, L. A., … Polzin, D. (2023, October 20). JOURNAL OF VETERINARY INTERNAL MEDICINE.

By: L. Cowgill*, G. Segev*, S. Vaden n, S. Ross*, C. Dufayet*, L. Cohn*, M. Nabity*, G. Farace* ...

author keywords: biomarker; creatinine; disease monitoring; inverse slope; symmetric dimethylarginine
TL;DR: In the studied CKD population, progressive dysfunction can be distinguished from stable kidney function by using the slope of creatinine−1 or SDMA−1. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: Web Of Science
Added: November 6, 2023

2023 journal article

Dirofilaria immitis Identified in Galapagos Sea Lions (Zalophus wollebaeki): A Wildlife Health and Conservation Concern

JOURNAL OF WILDLIFE DISEASES, 59(3), 487–494.

By: T. Gregory n, I. Livingston n, E. Hawkins n, A. Loyola*, A. Cave n, S. Vaden n, D. Deresienski n, M. Breen n ...

author keywords: Dirofilaria immitis; Galapagos Islands; heartworm; Zalophus wollebaeki
MeSH headings : Animals; Dogs; Male; Sea Lions; Dirofilaria immitis; Animals, Wild; Caniformia; Animals, Domestic; Endangered Species; Dirofilariasis / epidemiology; Dog Diseases
TL;DR: This is the first report of D. immitis infection in Galapagos sea lions, and widespread adoption of routine heartworm testing, prevention, and treatment in the canine population, and the control of mosquitos, could potentially reduce the disease impact on this endangered pinniped species. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 14, 2023

2023 article

Gastric pH and serum gastrin concentration in age-matched healthy dogs and dogs with chronic kidney disease

Grady, K., Ernst, E., Secoura, P. L., Price, J., Birkenheuer, A., Vaden, S. L., … Tolbert, M. K. (2023, October 24). JOURNAL OF VETERINARY INTERNAL MEDICINE, Vol. 10.

By: K. Grady n, E. Ernst n, P. Secoura n, J. Price*, A. Birkenheuer n, S. Vaden n, J. Lidbury*, E. Gould*, J. Steiner*, M. Tolbert n

author keywords: acid suppressant; azotemia; canine; famotidine; omeprazole
TL;DR: The results suggest that prophylactic gastric acid suppression in dogs with CKD is not warranted unless other clinical indications for use are present. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: November 20, 2023

2023 article

Lesser vestibular periurethral gland-like inflammation associated with lower urinary tract signs in a female dog

Price, M., Slead, T. S., Secoura, P. L., Kendall, A. R., & Vaden, S. L. (2023, September 29). JOURNAL OF VETERINARY INTERNAL MEDICINE.

By: M. Price n, T. Slead n, P. Secoura n, A. Kendall n & S. Vaden n

author keywords: dysuria; Skene's glands; skenitis; urinary tract infection
TL;DR: Inflammation in the region of the lesser vestibular paraurethral glands should be considered as a differential for female dogs presenting with chronic dysuria. (via Semantic Scholar)
Source: Web Of Science
Added: October 16, 2023

2023 article

Urinary cystatin B differentiates progressive versus stable IRIS Stage 1 chronic kidney disease in dogs

Segev, G., Vaden, S., Ross, S., Dufayet, C., Cohn, L. A., Farace, G., … Cowgill, L. D. (2023, October 10). JOURNAL OF VETERINARY INTERNAL MEDICINE.

By: G. Segev*, S. Vaden n, S. Ross*, C. Dufayet*, L. Cohn*, G. Farace*, D. Szlosek*, Z. Ouyang* ...

author keywords: biomarker; creatinine; disease monitoring; inverse slope; symmetric dimethylarginine
Source: Web Of Science
Added: October 30, 2023

2022 journal article

Creation of a Continent Urinary Bladder Reservoir Vascularized by Omentum as a Possible Surgical Option for Canine Trigonal/Urethral Urothelial Carcinoma

JOURNAL OF INVESTIGATIVE SURGERY, 35(3), 481–495.

By: A. Vlaming n, K. Mathews n, J. Hash n, E. Keenihan n, S. Sommer n, L. Borst n, S. Vaden n

author keywords: Transitional cell carcinoma; urothelial carcinoma; bladder mass; reservoir; ureter; cystectomy
MeSH headings : Animals; Carcinoma, Transitional Cell; Dogs; Female; Omentum / surgery; Urinary Bladder / diagnostic imaging; Urinary Bladder / surgery; Urinary Bladder Neoplasms / surgery; Urinary Reservoirs, Continent
TL;DR: The study’s objective was to evaluate a continent urine reservoir created from the urinary bladder body and vascularized solely by omentum to allow for primary UC resection while providing continence and limiting complications. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: January 19, 2021

2022 article

Detection of Escherichia coli and Enterococcus spp. in dogs with polymicrobial urinary tract infections: A 5-year retrospective study

Walker, G. K., Yustyniuk, V., Shamoun, J., Jacob, M. E., Correa, M., Vaden, S. L., & Borst, L. B. (2022, May 27). JOURNAL OF VETERINARY INTERNAL MEDICINE, Vol. 5.

By: G. Walker n, V. Yustyniuk*, J. Shamoun n, M. Jacob n, M. Correa n, S. Vaden n, L. Borst n

author keywords: antibiotics; bacteriuria; cystitis; urine culture
MeSH headings : Animals; Anti-Bacterial Agents / therapeutic use; Bacteriuria / drug therapy; Bacteriuria / epidemiology; Bacteriuria / veterinary; Dog Diseases / drug therapy; Dogs; Doxycycline; Enterococcus; Escherichia coli; Escherichia coli Infections / drug therapy; Escherichia coli Infections / veterinary; Gentamicins; Humans; Retrospective Studies; Urinary Tract Infections / drug therapy; Urinary Tract Infections / epidemiology; Urinary Tract Infections / veterinary
TL;DR: Polymicrobial UTI had more frequent adverse clinical outcomes for dogs and was more prevalent than monomicrobial UTI, and isolate antimicrobial resistance was more frequently resistant to doxycycline and gentamicin. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: June 6, 2022

2022 article

Prevalence of aldosterone breakthrough in dogs receiving renin-angiotensin system inhibitors for proteinuric chronic kidney disease

Ames, M. K., Vaden, S. L., Atkins, C. E., Palerme, J.-S., Langston, C. E., Grauer, G. F., … Webb, T. (2022, November 9). JOURNAL OF VETERINARY INTERNAL MEDICINE.

By: M. Ames*, S. Vaden n, C. Atkins n, J. Palerme*, C. Langston*, G. Grauer*, S. Shropshire*, C. Bove*, T. Webb*

author keywords: mineralocorticoid receptor antagonists; nephrology; renin-angiotensin-aldosterone system; urine aldosterone to creatinine ratio
MeSH headings : Dogs; Animals; Aldosterone; Renin-Angiotensin System / physiology; Creatinine / urine; Prospective Studies; Prevalence; Antihypertensive Agents / therapeutic use; Proteinuria / drug therapy; Proteinuria / veterinary; Renal Insufficiency, Chronic / drug therapy; Renal Insufficiency, Chronic / veterinary; Dog Diseases / drug therapy
TL;DR: Whether ABT occurs in dogs with CKDP and if it is associated with decreased efficacy in proteinuria reduction during RAS inhibitor treatment is investigated and its relationship with outcomes is evaluated. (via Semantic Scholar)
Source: Web Of Science
Added: November 21, 2022

2022 article

Shear wave elastography evaluation of cats with chronic kidney disease

Appleby, R. B., Vaden, S. L., Monteith, G., & Seiler, G. S. (2022, November 2). VETERINARY RADIOLOGY & ULTRASOUND.

By: R. Appleby*, S. Vaden*, G. Monteith* & G. Seiler n

author keywords: feline chronic kidney disease; Shear wave elastography; ultrasound
MeSH headings : Animals; Cats; Case-Control Studies; Cat Diseases / diagnostic imaging; Elasticity Imaging Techniques / veterinary; Elasticity Imaging Techniques / methods; Quality of Life; Renal Insufficiency, Chronic / diagnostic imaging; Renal Insufficiency, Chronic / veterinary; Ultrasonography
TL;DR: Shear wave elastography is not currently recommended as a tool to evaluate CKD in cats and further work is necessary, as there is no difference in shear wave velocities between groups and the intraclass correlation coefficient was only moderate. (via Semantic Scholar)
UN Sustainable Development Goal Categories
1. No Poverty (OpenAlex)
Source: Web Of Science
Added: November 14, 2022

2022 article

The use of autologous skeletal muscle progenitor cells for adjunctive treatment of presumptive urethral sphincter mechanism incompetence in female dogs

Vaden, S. L., Mathews, K. G., Yoo, J., Williams, J. K., Harris, T., Secoura, P., … Piedrahita, J. (2022, August 5). JOURNAL OF VETERINARY INTERNAL MEDICINE, Vol. 8.

By: S. Vaden n, K. Mathews n, J. Yoo*, J. Williams*, T. Harris n, P. Secoura n, J. Robertson n, K. Gleason n, H. Reynolds n, J. Piedrahita n

Contributors: J. Robertson n

author keywords: canine; regenerative medicine; stem cell; urinary incontinence
MeSH headings : Animals; Dog Diseases / surgery; Dogs; Female; Muscle, Skeletal; Stem Cells; Urethra / surgery; Urinary Incontinence / therapy; Urinary Incontinence / veterinary
TL;DR: Urethral submucosal injection of autologous skeletal muscle progenitor cells (skMPC) can be used adjunctively to improve continence in dogs with difficult to manage USMI. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 26, 2022

2021 article

Clinical features, outcome, and illness severity scoring in 32 dogs with urosepsis (2017-2018)

Perry, K. M., Lynch, A. M., Caudill, A., Vigani, A., Roberston, J. B., & Vaden, S. (2021, November 3). JOURNAL OF VETERINARY EMERGENCY AND CRITICAL CARE, Vol. 11.

By: K. Perry n, A. Lynch n, A. Caudill n, A. Vigani*, J. Roberston n & S. Vaden n

author keywords: APPLE score; canine; infection; MODS
MeSH headings : Animals; Dog Diseases / diagnosis; Dogs; Male; Multiple Organ Failure / veterinary; Patient Acuity; Retrospective Studies; Sepsis / diagnosis; Sepsis / veterinary
TL;DR: Survition of dogs with urosepsis was good and may be higher than for other sources of sepsis, and compared to survivors, nonsurvivors had more dysfunctional organs and higher illness severity scores, which may be helpful in the assessment and management of Dogs with u rosepsis. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: November 15, 2021

2021 article

Optimization of ultrasonographic ureteral jet detection and normal ureteral jet morphology in dogs

Gremillion, C., Cohen, E. B., Vaden, S., & Seiler, G. (2021, June 15). VETERINARY RADIOLOGY & ULTRASOUND, Vol. 6.

By: C. Gremillion n, E. Cohen n, S. Vaden n & G. Seiler n

author keywords: diuretic; ectopic ureter; ureteral obstruction
MeSH headings : Animals; Cross-Over Studies; Dogs; Prospective Studies; Ultrasonography / veterinary; Ureter / diagnostic imaging; Urinary Bladder / diagnostic imaging
TL;DR: Both intravenous and subcutaneous furosemide administration significantly increase ureteral jet detection with ultrasound secondary to differences in specific gravity, confirming results of prior studies. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: June 21, 2021

2021 journal article

Proteinuria in dogs with gallbladder mucocele formation: A retrospective case control study

JOURNAL OF VETERINARY INTERNAL MEDICINE, 35(2), 878–886.

By: C. Lindaberry n, S. Vaden n, K. Aicher n, G. Seiler n, J. Robertson n, R. Cianciolo*, C. Yang*, J. Gookin n

author keywords: canine; dipstick; glomerular disease; urinalysis
MeSH headings : Animals; Case-Control Studies; Dog Diseases / etiology; Dogs; Gallbladder; Mucocele / complications; Mucocele / veterinary; Proteinuria / veterinary; Retrospective Studies
TL;DR: Diagnosis and treatment of proteinuria in dogs with mucocele formation might minimize long term kidney morbidity in these patients. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: March 1, 2021

2021 article

Three-dimensional bladder ultrasound to measure daily urinary bladder volume in hospitalized dogs

Vasquez, E. J., Kendall, A., Musulin, S., & Vaden, S. L. (2021, July 31). JOURNAL OF VETERINARY INTERNAL MEDICINE, Vol. 7.

By: E. Vasquez n, A. Kendall n, S. Musulin n & S. Vaden n

author keywords: bladder volume; dogs; ultrasound; urine; urine residual volume
MeSH headings : Animals; Dog Diseases / diagnostic imaging; Dogs; Prospective Studies; Ultrasonography / veterinary; Urinary Bladder / diagnostic imaging; Urinary Catheterization / veterinary; Urinary Retention / diagnostic imaging; Urinary Retention / veterinary
TL;DR: Using 3D ultrasound to monitor daily UBV and URV in hospitalized dogs provides a safe estimate of bladder volume in real-time and might help in early identification of patients that are retaining urine, thereby preventing potential adverse effects of urethral catheterization or prolonged urinary retention. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
5. Gender Equality (Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 16, 2021

2021 article

Use of extracorporeal therapy in a dog with heatstroke

Tracy, A., Lynch, A., Messenger, K., Vaden, S., & Vigani, A. (2021, December 14). JOURNAL OF VETERINARY EMERGENCY AND CRITICAL CARE, Vol. 12.

By: A. Tracy n, A. Lynch n, K. Messenger n, S. Vaden n & A. Vigani*

author keywords: cytokines; extracorporeal therapy; heatstroke; hemodialysis; hemoperfusion
MeSH headings : Acute Kidney Injury / veterinary; Animals; Cytokines; Dog Diseases / therapy; Dogs; Heat Stroke / therapy; Heat Stroke / veterinary; Hemoperfusion / veterinary; Male
TL;DR: To the authors' knowledge, this represents the first clinical use of ECT consisting of HD and cytokine adsorption in the management of severe heat-related illness in a dog. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: December 20, 2021

2020 journal article

Outcomes Following Balloon Dilation of Benign Urethral Strictures in Dogs: Eight Cases (2005-2018)

JOURNAL OF THE AMERICAN ANIMAL HOSPITAL ASSOCIATION, 56(1), 23–29.

By: T. Gin n, P. Secoura n, T. Harris n & S. Vaden n

MeSH headings : Animals; Dilatation / methods; Dilatation / veterinary; Dog Diseases / surgery; Dogs; Female; Male; Retrospective Studies; Urethral Stricture / surgery; Urethral Stricture / veterinary
TL;DR: It is suggested that balloon dilation is an effective, minimally invasive procedure for the treatment of benign urethral strictures in dogs. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: February 22, 2021

2020 journal article

Three-dimensional bladder ultrasound for estimation of urine volume in dogs compared with traditional 2-dimensional ultrasound methods

JOURNAL OF VETERINARY INTERNAL MEDICINE, 34(6), 2460–2467.

By: A. Kendall n, E. Keenihan n, Z. Kern n, C. Lindaberry n, A. Birkenheuer n, G. Moore*, S. Vaden n

author keywords: bladder volume; dogs; ultrasound; urine
MeSH headings : Animals; Dogs; Point-of-Care Systems; Prospective Studies; Ultrasonography / veterinary; Urinary Bladder / diagnostic imaging
TL;DR: The tested 3D ultrasound device was found to be an accurate and rapid point‐of‐care tool for measuring UBV in dogs, providing a noninvasive method to estimate bladder volume in real time. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: November 24, 2020

2018 journal article

Agreement between Parallel Canine Blood and Urine Cultures: Is Urine Culture the Poor Man's Blood Culture?

JOURNAL OF CLINICAL MICROBIOLOGY, 56(9).

By: N. Barash n, A. Birkenheuer n, S. Vaden n & M. Jacob n

author keywords: blood culture; bloodstream infections; concordance; dogs; urine culture
MeSH headings : Animals; Bacteremia / diagnosis; Bacteremia / veterinary; Bacteria / growth & development; Bacteria / isolation & purification; Bacteriological Techniques / veterinary; Blood Culture / veterinary; Dog Diseases / blood; Dog Diseases / diagnosis; Dog Diseases / urine; Dogs; Retrospective Studies; Sensitivity and Specificity; Urinalysis / veterinary; Urinary Tract Infections / diagnosis; Urinary Tract Infections / veterinary
TL;DR: It is found that urine culture is neither a substitute nor a screen for blood culture, and should be performed in any potentially septic animal, especially those that are considered immunosuppressed. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: October 19, 2018

2018 journal article

Azotemia and Proteinuria in Dogs Infected with Babesia gibsoni

JOURNAL OF THE AMERICAN ANIMAL HOSPITAL ASSOCIATION, 54(3), 156–160.

By: T. Ullal*, A. Birkenheuer n & S. Vaden n

MeSH headings : Animals; Azotemia / diagnosis; Azotemia / veterinary; Babesia; Babesiosis / metabolism; DNA, Protozoan; Dog Diseases / diagnosis; Dog Diseases / metabolism; Dogs; Proteinuria / diagnosis; Proteinuria / veterinary; Retrospective Studies
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2018 journal article

Characteristics of Dogs with Biofilm-Forming Escherichia Coli Urinary Tract Infections

JOURNAL OF VETERINARY INTERNAL MEDICINE, 32(5), 1645–1651.

By: Z. Kern n, M. Jacob n, J. Gilbertie n, S. Vaden n & S. Lyle n

author keywords: chronic urinary tract infection; crystal violet; multidrug resistance; symptomatic urinary tract infection
MeSH headings : Animals; Biofilms / growth & development; Cross-Sectional Studies; Dog Diseases / microbiology; Dogs; Drug Resistance, Multiple, Bacterial; Escherichia coli / physiology; Escherichia coli Infections / microbiology; Escherichia coli Infections / veterinary; Female; Male; Retrospective Studies; Urinary Tract Infections / microbiology; Urinary Tract Infections / veterinary
TL;DR: The potential for biofilm formation should be considered whenever E. coli UTI is diagnosed and the association of antibiotic resistance and biofilm potential may affect treatment of UTIs, but additional investigation is warranted. (via Semantic Scholar)
Source: Web Of Science
Added: November 5, 2018

2018 journal article

Retrospective analysis of the effect of acid-suppressant therapy on clinicopathologic parameters of cats with chronic kidney disease

Journal of Feline Medicine and Surgery, 20(6), 520–527.

By: E. Gould*, J. Klos*, J. Price*, T. Harris n, S. Vaden n & M. Tolbert*

MeSH headings : Animals; Cat Diseases / chemically induced; Cat Diseases / drug therapy; Cats; Creatinine / blood; Disease Progression; Histamine H2 Antagonists / administration & dosage; Histamine H2 Antagonists / adverse effects; Proton Pump Inhibitors / administration & dosage; Proton Pump Inhibitors / adverse effects; Random Allocation; Renal Insufficiency, Chronic / chemically induced; Renal Insufficiency, Chronic / veterinary; Retrospective Studies
TL;DR: Results of this retrospective study suggest that cats with CKD receiving PPI therapy may develop alterations in blood sodium concentrations but do not experience more rapid progression of CKD. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: NC State University Libraries
Added: August 6, 2018

2018 journal article

Urine sodium concentrations are predictive of hypoadrenocorticism in hyponatraemic dogs: a retrospective pilot study

JOURNAL OF SMALL ANIMAL PRACTICE, 59(4), 228–231.

By: E. Lennon*, J. Hummel* & S. Vaden n

MeSH headings : Adrenal Insufficiency / complications; Adrenal Insufficiency / diagnosis; Adrenal Insufficiency / urine; Adrenal Insufficiency / veterinary; Animals; Diagnosis, Differential; Dog Diseases / diagnosis; Dog Diseases / urine; Dogs; Hyponatremia / etiology; Hyponatremia / urine; Hyponatremia / veterinary; Pilot Projects; Predictive Value of Tests; Retrospective Studies; Sodium / urine
TL;DR: The results suggest that urine sodium concentrations can be used to prioritise a differential diagnosis of hypoadrenocorticism in hyponatraemic dogs. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2017 journal article

Clinical Response and Side Effects Associated with Testosterone Cypionate for Urinary Incontinence in Male Dogs

JOURNAL OF THE AMERICAN ANIMAL HOSPITAL ASSOCIATION, 53(5), 285–290.

By: J. Palerme n, A. Mazepa n, R. Hutchins n, V. Ziglioli n & S. Vaden n

MeSH headings : Animals; Dog Diseases / drug therapy; Dogs; Male; Testosterone / adverse effects; Testosterone / analogs & derivatives; Testosterone / therapeutic use; Treatment Outcome; Urethra; Urinary Incontinence / drug therapy; Urinary Incontinence / veterinary
TL;DR: The results reported in this case series suggest that testosterone cypionate might be an effective and safe treatment option for male dogs with USMI. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2017 journal article

Clinical response and side effects associated with testosterone cypionate for urinary incontinence in male dogs

Journal of the American Animal Hospital Association, 53(5), 285–290.

By: J. Palerme n, A. Mazepa n, R. Hutchins n, V. Ziglioli n & S. Vaden n

UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: NC State University Libraries
Added: December 5, 2020

2017 journal article

Evaluation of serum cytokines in cats with and without degenerative joint disease and associated pain

Veterinary Immunology and Immunopathology, 183, 49–59.

By: M. Gruen n, K. Messenger n, A. Thomson n, E. Griffith n, L. Aldrich n, S. Vaden n, B. Lascelles n

author keywords: Biomarker; Immunoassay; Multiplex; Arthritis
MeSH headings : Animals; Cat Diseases / blood; Cat Diseases / physiopathology; Cats; Cytokines / blood; Female; Male; Osteoarthritis / blood; Osteoarthritis / diagnostic imaging; Osteoarthritis / physiopathology; Osteoarthritis / veterinary; Pain / veterinary; Radiography / veterinary
TL;DR: Evaluating the concentration of cytokines and chemokines in serum samples obtained from cats with and without degenerative joint disease and associated pain showed that cats with higher radiographic degenerative joints disease scores have higher serum concentrations of IL-4 and IL-8, while Cats with higher orthopedic exam pain scores haveHigher concentrations ofIL-8. (via Semantic Scholar)
UN Sustainable Development Goal Categories
10. Reduced Inequalities (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: July 20, 2019

2017 journal article

The Frequency and Clinical Implications of Bacteriuria in Chronically Paralyzed Dogs

Journal of Veterinary Internal Medicine, 31(6), 1790–1795.

By: S. Rafatpanah Baigi*, S. Vaden n & N. Olby n

author keywords: Canine; Incontinence; Spinal cord injury; Urinary tract infection
MeSH headings : Animals; Bacteriuria / complications; Bacteriuria / mortality; Bacteriuria / veterinary; Dog Diseases / pathology; Dogs; Female; Fever / veterinary; Male; Paraplegia / complications; Paraplegia / veterinary; Pyuria / veterinary; Retrospective Studies; Urinary Tract Infections / complications; Urinary Tract Infections / diagnosis; Urinary Tract Infections / veterinary
TL;DR: Bacteriuria is common in paralyzed dogs but does not cause fever; diagnostic criteria of UTI are unclear, and an association of bacteriuria with survival, but this needs further confirmation. (via Semantic Scholar)
Sources: Web Of Science, Crossref, NC State University Libraries, ORCID
Added: August 6, 2018

2017 journal article

Use of a Granulocyte Immunofluorescence Assay Designed for Humans for Detection of Antineutrophil Cytoplasmic Antibodies in Dogs with Chronic Enteropathies

JOURNAL OF VETERINARY INTERNAL MEDICINE, 31(4), 1062–1066.

By: J. Florey*, A. Viall*, S. Streu*, V. DiMuro*, A. Riddle*, J. Kirk*, L. Perazzotti, K. Affeldt* ...

author keywords: Antineutrophil cytoplasmic antibodies; Chronic enteropathy; Food-responsive disease; Indirect immunofluorescence
MeSH headings : Animals; Antibodies, Antineutrophil Cytoplasmic / blood; Antibodies, Antineutrophil Cytoplasmic / immunology; Case-Control Studies; Dog Diseases / blood; Dog Diseases / diagnosis; Dog Diseases / immunology; Dogs; Female; Fluorescent Antibody Technique, Indirect / methods; Fluorescent Antibody Technique, Indirect / veterinary; Gastrointestinal Diseases / blood; Gastrointestinal Diseases / diagnosis; Gastrointestinal Diseases / immunology; Gastrointestinal Diseases / veterinary; Granulocytes / immunology; Male
TL;DR: A commercially available granulocyte IIF assay designed for humans could be used to detect perinuclear antineutrophil cytoplasmic antibodies in dogs, and agreement with the previously published method was good. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2016 journal article

A comparison of serum and plasma cytokine values using a multiplexed assay in cats

Veterinary Immunology and Immunopathology, 182, 69–73.

By: M. Gruen n, K. Messenger n, A. Thomson n, E. Griffith n, H. Paradise n, S. Vaden n, B. Lascelles n

author keywords: Biomarker; Immunoassay; Feline
MeSH headings : Animals; Biomarkers / blood; Blood Chemical Analysis / methods; Cats / blood; Cats / immunology; Cytokines / blood; Immunoassay / methods; Plasma / immunology
TL;DR: While serum and plasma agreement was generally good, detection was improved using serum samples, and alterations of cytokine concentrations have been associated with joint deterioration and pain in humans, similar changes have not been investigated in cats. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018

2016 journal article

Effect of Cranberry Extract on the Frequency of Bacteriuria in Dogs with Acute Thoracolumbar Disk Herniation: A Randomized Controlled Clinical Trial

Journal of Veterinary Internal Medicine, 31(1), 60–68.

By: N. Olby n, S. Vaden n, K. Williams n, E. Griffith n, T. Harris n, C. Mariani n, K. Muñana n, P. Early n ...

Contributors: N. Olby n, S. Vaden n, K. Williams n, E. Griffith n, T. Harris n, C. Mariani n, K. Muñana n, P. Early n ...

author keywords: Escherichia coli; Incontinence; Proanthocyanidins; Spinal cord injury
MeSH headings : Administration, Oral; Animals; Anti-Infective Agents / administration & dosage; Anti-Infective Agents / therapeutic use; Bacteriuria / complications; Bacteriuria / drug therapy; Bacteriuria / urine; Bacteriuria / veterinary; Dog Diseases / drug therapy; Dogs; Female; Intervertebral Disc Displacement / complications; Intervertebral Disc Displacement / veterinary; Male; Plant Extracts / administration & dosage; Plant Extracts / therapeutic use; Prospective Studies; Single-Blind Method; Thoracic Vertebrae; Treatment Outcome; Urinary Tract Infections / complications; Urinary Tract Infections / drug therapy; Urinary Tract Infections / urine; Urinary Tract Infections / veterinary; Vaccinium macrocarpon
TL;DR: This clinical trial did not show a benefit of oral cranberry extract but had low power, but a possible association between urine AAA and lower risk of E. coli bacteriuria was identified. (via Semantic Scholar)
Sources: Web Of Science, Crossref, ORCID, NC State University Libraries
Added: August 6, 2018

2016 journal article

Management of Proteinuria in Dogs and Cats with Chronic Kidney Disease

VETERINARY CLINICS OF NORTH AMERICA-SMALL ANIMAL PRACTICE, 46(6), 1115-+.

By: S. Vaden n & J. Elliott*

author keywords: Urine protein:creatinine ratio; Proteinuria; Hypertension; Angiotensin; Aldosterone; Glomerular; Chronic kidney disease
MeSH headings : Animals; Cat Diseases / urine; Cats; Dog Diseases / urine; Dogs; Proteinuria / therapy; Proteinuria / veterinary; Renal Insufficiency, Chronic / therapy; Renal Insufficiency, Chronic / urine; Renal Insufficiency, Chronic / veterinary
TL;DR: Targeted patient monitoring is essential when instituting management of proteinuria, and administration of immunosuppressive agents should be considered in animals with glomerular proteinuria that have not responded to standard therapy. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2016 journal article

World Small Animal Veterinary Association Renal Pathology Initiative: Classification of Glomerular Diseases in Dogs

VETERINARY PATHOLOGY, 53(1), 113–135.

By: R. Cianciolo*, F. Mohr*, L. Aresu*, C. Brown*, C. James, J. Jansen*, W. Spangler, J. Lugt* ...

MeSH headings : Amyloidosis / classification; Amyloidosis / immunology; Amyloidosis / pathology; Amyloidosis / veterinary; Animals; Antigen-Antibody Complex; Cluster Analysis; Dog Diseases / classification; Dog Diseases / immunology; Dog Diseases / pathology; Dogs; Fluorescent Antibody Technique / veterinary; Glomerulonephritis / classification; Glomerulonephritis / immunology; Glomerulonephritis / pathology; Glomerulonephritis / veterinary; Kidney / pathology; Kidney Diseases / classification; Kidney Diseases / immunology; Kidney Diseases / pathology; Kidney Diseases / veterinary; Kidney Glomerulus / pathology; Microscopy, Electron, Transmission / veterinary; Pathology, Veterinary; Retrospective Studies
TL;DR: Cluster analysis performed on only the LM parameters led to misdiagnosis of 22 of the 89 cases—that is, ICGN cases moved to the non-ICGN branch of the dendrogram or vice versa, thereby emphasizing the importance of advanced diagnostic modalities in the evaluation of canine glomerular disease. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2015 journal article

Cardiovascular-renal axis disorders in the domestic dog and cat: a veterinary consensus statement

JOURNAL OF SMALL ANIMAL PRACTICE, 56(9), 537–552.

By: J. Pouchelon*, C. Atkins n, C. Bussadori, M. Oyama*, S. Vaden n, J. Bonagura*, V. Chetboul*, L. Cowgill* ...

Contributors: J. Pouchelon*, C. Atkins n, C. Bussadori, M. Oyama*, S. Vaden n, J. Bonagura*, V. Chetboul*, L. Cowgill* ...

MeSH headings : Animals; Cardio-Renal Syndrome / diagnosis; Cardio-Renal Syndrome / epidemiology; Cardio-Renal Syndrome / therapy; Cardio-Renal Syndrome / veterinary; Cat Diseases / diagnosis; Cat Diseases / epidemiology; Cat Diseases / therapy; Cats; Consensus; Delphi Technique; Dog Diseases / diagnosis; Dog Diseases / epidemiology; Dog Diseases / therapy; Dogs; Practice Guidelines as Topic; Veterinary Medicine
Sources: Web Of Science, ORCID
Added: August 6, 2018

2015 journal article

Identification of Parabodo caudatus (class Kinetoplastea) in urine voided from a dog with hematuria

JOURNAL OF VETERINARY DIAGNOSTIC INVESTIGATION, 27(1), 117–120.

By: M. Vandersea n, A. Birkenheuer n, R. Litaker n, S. Vaden n, J. Renschler n & J. Gookin n

author keywords: Bodo urinarius; canine; flagellate; Parabodo caudatus; protozoa
MeSH headings : Animals; DNA, Protozoan / genetics; Dog Diseases / parasitology; Dog Diseases / urine; Dogs; Euglenozoa Infections / parasitology; Euglenozoa Infections / urine; Euglenozoa Infections / veterinary; Hematuria / parasitology; Hematuria / urine; Hematuria / veterinary; Kinetoplastida / genetics; Kinetoplastida / isolation & purification; Male; Polymerase Chain Reaction / veterinary; RNA, Ribosomal, 18S / genetics
TL;DR: A voided urine sample was observed to contain biflagellate protozoa 5 days following an episode of gross hematuria, and Parabodo caudatus organisms were unable to be demonstrated cytologically or by means of PCR in samples collected from the dog’s environment. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 6, 2018

2015 article

Management of transitional cell carcinoma of the urinary bladder in dogs: Important challenges to consider

Nolan, M. W., Gieger, T. L., & Vaden, S. L. (2015, August). VETERINARY JOURNAL, Vol. 205, pp. 126–127.

By: M. Nolan n, T. Gieger n & S. Vaden n

MeSH headings : Animals; Carcinoma, Transitional Cell; Dog Diseases; Dogs; Urinary Bladder; Urinary Bladder Neoplasms
TL;DR: Opinions on diagnosis and staging of TCC are shared, and how these may impact on treatment decisions are shared. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2014 personal communication

Chronic kidney disease in cats

By: B. Lascelles, M. Gruen, S. Vaden, B. Hansen, S. Roe & L. Hardie

Source: NC State University Libraries
Added: August 6, 2018

2014 journal article

Prevalence and classification of chronic kidney disease in cats randomly selected from four age groups and in cats recruited for degenerative joint disease studies

JOURNAL OF FELINE MEDICINE AND SURGERY, 16(6), 465–472.

By: C. Marino n, B. Lascelles n, S. Vaden n, M. Gruen n & S. Marks n

MeSH headings : Age Factors; Animals; Cat Diseases / classification; Cat Diseases / diagnosis; Cat Diseases / epidemiology; Cats; Osteoarthritis / classification; Osteoarthritis / epidemiology; Osteoarthritis / veterinary; Prevalence; Renal Insufficiency, Chronic / classification; Renal Insufficiency, Chronic / epidemiology; Renal Insufficiency, Chronic / veterinary; Retrospective Studies; Risk Factors
TL;DR: Significant concurrence between CKD and DJD in cats of all ages is found, indicating the need for increased screening for CKD when selecting DJD treatments and the idea of a relationship and causal commonality between CKd andDJD owing to the striking concurrence across age groups and life stages. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2014 journal article

Vaginal Microbiota of Spayed Dogs with or without Recurrent Urinary Tract Infections

JOURNAL OF VETERINARY INTERNAL MEDICINE, 28(2), 300–304.

By: R. Hutchins*, S. Vaden n, M. Jacob n, T. Harris n, K. Bowles n, M. Wood n, C. Bailey n

author keywords: Recurrent urinary tract infection; Lactic acid-producing bacteria
MeSH headings : Animals; Dog Diseases / microbiology; Dogs / microbiology; Female; Microbiota; Ovariectomy / veterinary; Recurrence; Urinary Tract Infections / microbiology; Urinary Tract Infections / veterinary; Vagina / microbiology
TL;DR: The vaginal microbiota of spayed female dogs with recurrent UTI was similar to the control population of normal, spayed male dogs and vaginal bacteria isolate from vaginal swabs obtained from each dog. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2013 journal article

Consensus Guidelines for Immunosuppressive Treatment of Dogs with Glomerular Disease Absent a Pathologic Diagnosis

JOURNAL OF VETERINARY INTERNAL MEDICINE, 27, S55–S59.

By: B. Pressler*, S. Vaden n, B. Gerber*, C. Langston* & D. Polzin*

author keywords: Canine; Glomerulonephritis; Glomerulopathy; Proteinuria
MeSH headings : Animals; Azotemia / drug therapy; Azotemia / immunology; Azotemia / veterinary; Consensus; Dog Diseases / drug therapy; Dog Diseases / immunology; Dog Diseases / urine; Dogs; Glomerulonephritis / drug therapy; Glomerulonephritis / immunology; Glomerulonephritis / urine; Glomerulonephritis / veterinary; Immunosuppressive Agents / therapeutic use; Proteinuria / drug therapy; Proteinuria / immunology; Proteinuria / veterinary
TL;DR: Recommendations can help guide the decision about renal biopsy in patients with proteinuria as well as the use of immunosuppressive drugs in those patients where the decision was made not to perform renal biopsies. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2013 journal article

Consensus Recommendations for Standard Therapy of Glomerular Disease in Dogs

JOURNAL OF VETERINARY INTERNAL MEDICINE, 27, S27–S43.

By: S. Brown*, J. Elliott*, T. Francey*, D. Polzin* & S. Vaden n

author keywords: Amyloidosis; Chronic renal failure; Glomerulonephritis; Protein losing nephropathy
MeSH headings : Angiotensin Receptor Antagonists / therapeutic use; Angiotensin-Converting Enzyme Inhibitors / therapeutic use; Animals; Antihypertensive Agents / therapeutic use; Consensus; Dog Diseases / drug therapy; Dog Diseases / pathology; Dogs; Glomerulonephritis / drug therapy; Glomerulonephritis / pathology; Glomerulonephritis / veterinary; Mineralocorticoid Receptor Antagonists / therapeutic use; Renin-Angiotensin System
TL;DR: Consensus recommendations target the evaluation and management of proteinuria, inhibition of the renin-angiotensin-aldosterone system, modification in dietary intake with special consideration for those nutrients with renal effects, diagnosis and treatment of systemic hypertension, and evaluation andmanagement of body fluid volume status in dogs with glomerular disease. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2013 review

Familial renal disease in soft-coated wheaten terriers

[Review of ]. JOURNAL OF VETERINARY EMERGENCY AND CRITICAL CARE, 23(2), 174–183.

By: S. Vaden*, M. Littman* & R. Cianciolo*

author keywords: dogs; glomerulonephropathy; inherited disorders; protein losing nephropathy; protein losing enteropathy
MeSH headings : Animals; Dog Diseases / genetics; Dogs; Kidney Diseases / genetics; Kidney Diseases / veterinary
TL;DR: There is also strong evidence supporting a high prevalence of food hypersensitivity reactions in SCWT, although it is unclear if these reactions have a primary or secondary role in the development of PLE. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2013 journal article

Hypercoagulability in Dogs with Protein-Losing Nephropathy as Assessed by Thromboelastography

JOURNAL OF VETERINARY INTERNAL MEDICINE, 27(3), 462–468.

By: E. Lennon n, R. Hanel n, J. Walker n & S. Vaden n

author keywords: Antithrombin; Hypoalbuminemia; Proteinuria; Thromboembolism
MeSH headings : Animals; Blood Coagulation Disorders / blood; Blood Coagulation Disorders / epidemiology; Blood Coagulation Disorders / veterinary; Dog Diseases / blood; Dog Diseases / pathology; Dogs; Female; Kidney Diseases / blood; Kidney Diseases / complications; Kidney Diseases / pathology; Kidney Diseases / veterinary; Male; Thrombelastography / veterinary
TL;DR: The results indicate that dogs with PLN have TEG values that demonstrate hypercoagulability compared with a control population but that antithrombin, SALB, or UPC cannot be used in isolation to predict this result. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2013 journal article

Management of bilateral idiopathic renal hematuria in a dog with silver nitrate

Canadian Veterinary Journal, 54, 761–764.

By: M. DiCicco, T. Fetzer, P. Secoura, K. Jermyn, T. Hill, S. Chalhoub, S. Vaden

Source: NC State University Libraries
Added: August 13, 2021

2013 journal article

Suspected carprofen toxicosis caused by coprophagia in a dog

JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, 243(5), 709–711.

By: R. Hutchins n, K. Messenger* & S. Vaden*

MeSH headings : Animals; Anti-Inflammatory Agents, Non-Steroidal / adverse effects; Carbazoles / adverse effects; Coprophagia; Dog Diseases / chemically induced; Dogs; Female
TL;DR: Findings for the dog of this report suggested that carprofen toxicosis can be caused by consumption of feces of another dog receiving the drug. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2013 journal article

The Effect of an Oral Probiotic Containing Lactobacillus, Bifidobacterium, and Bacillus Species on the Vaginal Microbiota of Spayed Female Dogs

JOURNAL OF VETERINARY INTERNAL MEDICINE, 27(6), 1368–1371.

By: R. Hutchins n, C. Bailey n, M. Jacob n, T. Harris n, M. Wood n, K. Saker n, S. Vaden n

author keywords: Lactic acid-producing bacteria; Recurrent urinary tract infection
MeSH headings : Animals; Bacillus / genetics; Bacillus / isolation & purification; Bifidobacterium / genetics; Bifidobacterium / isolation & purification; Dog Diseases / microbiology; Dog Diseases / prevention & control; Dogs; Female; Lactobacillus / genetics; Lactobacillus / isolation & purification; Microbiota / genetics; Probiotics / pharmacology; Sequence Analysis, DNA; Urinary Tract Infections / microbiology; Urinary Tract Infections / prevention & control; Urinary Tract Infections / veterinary; Vagina / microbiology
TL;DR: Administration of this oral probiotic supplement for a 2- or 4-week period did not increase the prevalence of vaginal LAB in dogs and Enterococcus canintestini was the most common LAB isolated from all dogs in this study, although it was not included in the probiotics supplement. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2012 journal article

Renal Disease in Cats Infected with Feline Immunodeficiency Virus

JOURNAL OF VETERINARY INTERNAL MEDICINE, 26(2), 238–243.

By: K. Baxter, J. Levy*, C. Edinboro*, S. Vaden* & M. Tompkins n

author keywords: Azotemia; Glomerulonephropathy; Human immunodeficiency virus - associated nephropathy; Proteinuria
MeSH headings : Animals; Blood Urea Nitrogen; CD4-CD8 Ratio / veterinary; CD4-Positive T-Lymphocytes / immunology; CD4-Positive T-Lymphocytes / virology; CD8-Positive T-Lymphocytes / immunology; CD8-Positive T-Lymphocytes / virology; Cats; Creatinine / blood; Cross-Sectional Studies; Feline Acquired Immunodeficiency Syndrome / blood; Feline Acquired Immunodeficiency Syndrome / complications; Feline Acquired Immunodeficiency Syndrome / immunology; Feline Acquired Immunodeficiency Syndrome / virology; Female; Immunodeficiency Virus, Feline / isolation & purification; Kidney Diseases / blood; Kidney Diseases / immunology; Kidney Diseases / veterinary; Kidney Diseases / virology; Male; Prospective Studies; Proteinuria / veterinary; Retrospective Studies; Specific Pathogen-Free Organisms; Statistics, Nonparametric
TL;DR: Proteinuria but not azotemia was associated with natural FIV infection and neither neuter status nor health status were risk factors for proteinuria in FIV-infected cats, but UPC was positively correlated with the CD4+:CD8+ T lymphocyte ratio. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2011 journal article

Assessment of urine solute and matrix effects on the performance of an enzyme-linked immunosorbent assay for measurement of interleukin-6 in dog urine

JOURNAL OF VETERINARY DIAGNOSTIC INVESTIGATION, 23(2), 316–320.

By: M. Wood n, S. Nordone n, S. Vaden n & E. Breitschwerdt n

author keywords: Cytokine; enzyme-linked immunosorbent assay; interleukin-6; matrix; urine
TL;DR: The role of urine pH, USG, and matrix are examined while optimizing a canine-specific chemiluminescent ELISA for the measurement of IL-6 in the urine of dogs to underscores the importance of critically optimizing testing modalities for biomarkers, particularly if they are immunologic in origin. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2011 journal article

Comparison of Signalment, Clinicopathologic Findings, Histologic Diagnosis, and Prognosis in Dogs with Glomerular Disease with or without Nephrotic Syndrome

JOURNAL OF VETERINARY INTERNAL MEDICINE, 25(2), 206–214.

By: E. Klosterman*, G. Moore*, J. Galvao*, S. DiBartola*, R. Groman*, J. Whittemore*, S. Vaden n, T. Harris n ...

author keywords: Amyloidosis; Ascites; Membranoproliferative glomerulonephritis; Membranous glomerulopathy
MeSH headings : Albuminuria / etiology; Albuminuria / veterinary; Animals; Azotemia / etiology; Azotemia / veterinary; Case-Control Studies; Creatinine / blood; Creatinine / metabolism; Dog Diseases / mortality; Dog Diseases / pathology; Dogs; Female; Glomerulonephritis, Membranous; Kidney Diseases / complications; Kidney Diseases / mortality; Kidney Diseases / pathology; Kidney Diseases / veterinary; Kidney Glomerulus / pathology; Male; Nephrotic Syndrome / complications; Nephrotic Syndrome / mortality; Nephrotic Syndrome / pathology; Nephrotic Syndrome / veterinary; Prognosis; Proteinuria / etiology; Proteinuria / veterinary; Retrospective Studies
TL;DR: Presence of Nephrotic syndrome is associated with poorer prognosis in dogs with nonazotemic glomerular disease and Preventing development of NS is warranted; however, specific interventions were not evaluated. (via Semantic Scholar)
UN Sustainable Development Goal Categories
1. No Poverty (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2011 review

Glomerular Disease

[Review of ]. TOPICS IN COMPANION ANIMAL MEDICINE, 26(3), 128–134.

By: S. Vaden n

author keywords: glomerular disease; glomerulonephritis; amyloidosis; glomerulopathy; proteinuria
MeSH headings : Animals; Cat Diseases / pathology; Cat Diseases / therapy; Cat Diseases / urine; Cats; Dog Diseases / pathology; Dog Diseases / therapy; Dog Diseases / urine; Dogs; Glomerulonephritis / pathology; Glomerulonephritis / therapy; Glomerulonephritis / urine; Glomerulonephritis / veterinary; Proteinuria / pathology; Proteinuria / therapy; Proteinuria / urine; Proteinuria / veterinary
TL;DR: The general diagnosis and management of dogs with glomerular disease is discussed and it may be reasonable to consider immunosuppressive therapy in dogs that have developed a form of glomerulonephritis secondary to a steroid-responsive disease. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2011 article

Renal effects of Dirofilaria immitis in experimentally and naturally infected cats

Atkins, C. E., Vaden, S. L., Arther, R. G., Ciszewski, D. K., Davis, W. L., Ensley, S. M., & Chopade, N. H. (2011, March 22). VETERINARY PARASITOLOGY, Vol. 176, pp. 317–323.

By: C. Atkins n, S. Vaden n, R. Arther*, D. Ciszewski*, W. Davis*, S. Ensley*, N. Chopade*

author keywords: Feline heartworm; Proteinuria; Microalbuminuria
MeSH headings : Animals; Antibodies, Helminth / blood; Antigens, Helminth / blood; Cat Diseases / parasitology; Cat Diseases / urine; Cats; Dirofilaria immitis / pathogenicity; Dirofilariasis / parasitology; Dirofilariasis / urine; Female; Larva / pathogenicity; Male; Proteinuria / parasitology; Proteinuria / urine; Proteinuria / veterinary; Risk Factors
TL;DR: It is concluded that cats infected with mature adult heartworms are at risk for developing proteinuria and that this is recognized relatively soon after infection. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2010 journal article

Comparison of urine dipstick, sulfosalicylic acid, urine protein-to-creatinine ratio, and species-specific ELISA methods for detection of albumin in urine samples of cats and dogs

JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, 236(8), 874–879.

By: S. Lyon, M. Sanderson, S. Vaden*, M. Lappin, W. Jensen & G. Grauer

MeSH headings : Albuminuria / diagnosis; Albuminuria / veterinary; Animals; Benzenesulfonates; Cat Diseases / diagnosis; Cat Diseases / urine; Cats / urine; Creatinine; Dog Diseases / diagnosis; Dog Diseases / urine; Dogs / urine; Enzyme-Linked Immunosorbent Assay / veterinary; Proteinuria / veterinary; Reagent Strips; Salicylates / chemistry; Sensitivity and Specificity; Species Specificity
TL;DR: Caution should be used when interpreting a positive test result of a dipstick or SSA test for canine or feline albuminuria, and stronger positive test results (>or= 2+) were used. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2010 journal article

Outcome assessment of a computer-animated model for learning about the regulation of glomerular filtration rate

ADVANCES IN PHYSIOLOGY EDUCATION, 34(2), 97–105.

By: J. Gookin*, D. McWhorter n, S. Vaden* & L. Posner*

author keywords: medical education; veterinary; interactive; renal physiology
MeSH headings : Computer Simulation; Education, Veterinary / methods; Glomerular Filtration Rate / physiology; Humans; Physiology / education; Problem-Based Learning / methods
TL;DR: It is suggested that the animated model is a useful, effective, and well-received tool for learning and creating a visual memory of the regulatory mechanisms of GFR. (via Semantic Scholar)
UN Sustainable Development Goal Categories
4. Quality Education (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2010 journal article

Prevalence of urinary tract infection in dogs after surgery for thoracolumbar intervertebral disc extrusion

Journal of Veterinary Internal Medicine, 24(5), 1106–1111.

By: N. Olby n, E. MacKillop, S. Cerda-Gonzalez*, S. Moore*, K. Munana n, M. Graffinger, J. Osborne n, S. Vaden n

Contributors: N. Olby n, E. MacKillop, S. Cerda-Gonzalez*, S. Moore*, K. Muñana n, M. Grafinger*, J. Osborne n, S. Vaden n

author keywords: Incontinence; Micturition; Spinal cord injury
MeSH headings : Animals; Dog Diseases / etiology; Dogs; Female; Intervertebral Disc Displacement / surgery; Intervertebral Disc Displacement / veterinary; Male; Risk Factors; Surgical Procedures, Operative / adverse effects; Surgical Procedures, Operative / veterinary; Urinary Tract Infections / etiology; Urinary Tract Infections / veterinary
TL;DR: There is a high prevalence of UTIs, many of which are occult, in the 3 months after surgery for thoracolumbar IVDE, and these dogs should be routinely monitored for UTI with urine culture regardless of urinalysis results. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2010 journal article

The prevalence of albuminuria in dogs and cats in an ICU or recovering from anesthesia

JOURNAL OF VETERINARY EMERGENCY AND CRITICAL CARE, 20(5), 479–487.

By: S. Vaden n, C. Turman n, T. Harris n & S. Marks n

author keywords: microalbuminuria; urine albumin
MeSH headings : Albuminuria / veterinary; Anesthesia / veterinary; Anesthesia Recovery Period; Animals; Cat Diseases / urine; Cats; Dog Diseases / urine; Dogs; Intensive Care Units
TL;DR: The prevalence of albuminuria in animals admitted to the ICU or recovering from anesthesia is higher than reported previously and transient in some patients, and the presence ofalbuminuria may be a negative prognostic indicator in this population of animals. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2010 journal article

The use of pooled vs serial urine samples to measure urine protein:creatinine ratios

VETERINARY CLINICAL PATHOLOGY, 39(1), 53–56.

By: D. LeVine n, D. Zhang n, T. Harris n & S. Vaden n

author keywords: Dog; proteinuria; protein:creatinine ratio; UPC
MeSH headings : Animals; Creatinine / urine; Dog Diseases / diagnosis; Dog Diseases / urine; Dogs; Kidney Failure, Chronic / urine; Kidney Failure, Chronic / veterinary; Proteinuria / veterinary; Specimen Handling
TL;DR: Measuring the UPC ratio in a pooled sample containing equal volumes of several different urine specimens from the same dog provides a reliable and cost-effective alternative to assessing multiple UPC ratios on several specimens fromThe same dog. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2009 book

Blackwell's five-minute veterinary consult laboratory tests and diagnostic procedures, canine & feline

Ames, Iowa: Wiley-Blackwell.

Shelly Vaden

Source: NC State University Libraries
Added: August 6, 2018

2009 journal article

Use of Computed Tomography (CT) Scanning and Colorectal New Methylene Blue Infusion in Evaluation of an English Bulldog with a Rectourethral Fistula

JOURNAL OF VETERINARY INTERNAL MEDICINE, 23(4), 931–934.

By: A. Cruse n, S. Vaden n, K. Mathews n, T. Hill n & I. Robertson n

MeSH headings : Animals; Dog Diseases / diagnosis; Dogs; Male; Methylene Blue / administration & dosage; Rectal Fistula / diagnosis; Rectal Fistula / surgery; Rectal Fistula / veterinary; Tomography, X-Ray Computed / veterinary; Urethral Diseases / diagnosis; Urethral Diseases / surgery; Urethral Diseases / veterinary
Source: Web Of Science
Added: August 6, 2018

2008 journal article

Concurrent Hepatic Copper Toxicosis and Fanconi's Syndrome in a Dog

Journal of Veterinary Internal Medicine, 22(1), 219–222.

By: T. Hill n, E. Breitschwerdt n, T. Cecere n & S. Vaden n

MeSH headings : Animals; Chelation Therapy / veterinary; Chemical and Drug Induced Liver Injury; Copper / metabolism; Dog Diseases / chemically induced; Dog Diseases / diagnosis; Dog Diseases / therapy; Dogs; Fanconi Syndrome / diagnosis; Fanconi Syndrome / therapy; Fanconi Syndrome / veterinary; Kidney / pathology; Liver / pathology; Liver Diseases / diagnosis; Liver Diseases / veterinary; Male; Metal Metabolism, Inborn Errors / diagnosis; Metal Metabolism, Inborn Errors / therapy; Metal Metabolism, Inborn Errors / veterinary
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2008 article

Evaluation of perinuclear anti-neutrophilic cytoplasmic autoantibodies as an early marker of protein-losing enteropathy and protein-losing nephropathy in Soft Coated Wheaten Terriers

Allenspach, K., Lomas, B., Wieland, B., Harris, T., Pressler, B., Mancho, C., … Vaden, S. L. (2008, October). AMERICAN JOURNAL OF VETERINARY RESEARCH, Vol. 69, pp. 1301–1304.

By: K. Allenspach, B. Lomas, B. Wieland, T. Harris*, B. Pressler*, C. Mancho, G. Lees, S. Vaden*

MeSH headings : Animals; Antibodies, Antineutrophil Cytoplasmic / blood; Autoantibodies / blood; Dog Diseases / blood; Dog Diseases / immunology; Dogs; Kidney Diseases / etiology; Kidney Diseases / immunology; Kidney Diseases / veterinary; Protein-Losing Enteropathies / complications; Protein-Losing Enteropathies / immunology; Protein-Losing Enteropathies / veterinary; Species Specificity
TL;DR: Most dogs in this study affected with PLE, PLN, or both had positive results for pANCAs before clinicopathologic evidence of disease was detected and may be useful as an early noninvasive test of disease in SCWTs. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2007 journal article

Antibiotic-resistant Corynebacterium jeikeium urinary tract infection in a cat

JOURNAL OF THE AMERICAN ANIMAL HOSPITAL ASSOCIATION, 43(1), 61–64.

By: M. Puskar n, C. Lemons n, M. Papich n, S. Vaden n & A. Birkenheuer n

MeSH headings : Animals; Anti-Infective Agents / administration & dosage; Anti-Infective Agents / pharmacology; Bacteriuria / microbiology; Cat Diseases / drug therapy; Cat Diseases / microbiology; Cats; Corynebacterium / drug effects; Corynebacterium / genetics; Corynebacterium / isolation & purification; Corynebacterium Infections / drug therapy; Corynebacterium Infections / microbiology; Corynebacterium Infections / veterinary; Drug Resistance, Multiple, Bacterial; Enzyme Inhibitors / administration & dosage; Enzyme Inhibitors / pharmacology; Male; Microbial Sensitivity Tests / veterinary; RNA, Ribosomal, 16S / genetics; Treatment Outcome; Urinary Tract Infections / drug therapy; Urinary Tract Infections / microbiology; Urinary Tract Infections / veterinary
TL;DR: Urine culture and gene sequencing identified Corynebacterium jeikeium, which was resistant to antibiotics and appeared to be the cause of the urinary tract infection. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 6, 2018

2007 journal article

Cystoscopic-guided balloon dilation of a urethral stricture in a female dog

Canadian Veterinary Journal, 48(7), 731–733.

Source: NC State University Libraries
Added: August 6, 2018

2006 journal article

Evaluation of colonoscopic allergen provocation as a diagnostic tool in dogs with proven food hypersensitivity reactions

JOURNAL OF SMALL ANIMAL PRACTICE, 47(1), 21–26.

By: K. Allenspach*, S. Vaden*, T. Harris*, A. Grone*, M. Doherr*, M. Griot-Wenk*, S. Bischoff*, F. Gaschen*

MeSH headings : Allergens / administration & dosage; Allergens / adverse effects; Animals; Case-Control Studies; Colon / immunology; Colonoscopy / methods; Colonoscopy / veterinary; Dog Diseases / diagnosis; Dog Diseases / pathology; Dogs; Female; Food Hypersensitivity / diagnosis; Food Hypersensitivity / pathology; Food Hypersensitivity / veterinary; Immunoglobulin E / immunology; Male
TL;DR: The accuracy of this new test may be higher than that for gastric sensitivity testing and holds promise as a new test to confirm the diagnosis of suspect IgE-mediated food allergy in dogs. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2005 article

Assessment and management of proteinuria in dogs and cats: 2004 ACVIM forum consensus statement (small animal)

JOURNAL OF VETERINARY INTERNAL MEDICINE, Vol. 19, pp. 377–385.

By: G. Lees*, S. Brown*, J. Elliott*, G. Grauer* & S. Vaden n

author keywords: albuminuria; canine; chronic kidney disease; feline
Source: Web Of Science
Added: August 6, 2018

2005 journal article

Clinical, clinicopathologic, radiographic, and ultrasonographic abnormalities in cats with ureteral calculi: 163 cases (1984-2002)

JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, 226(6), 932–936.

By: A. Kyles*, E. Hardie n, B. Wooden*, C. Adin*, E. Stone n, C. Gregory*, K. Mathews n, L. Cowgill ...

MeSH headings : Animals; Cat Diseases / diagnostic imaging; Cats; Female; Hypercalcemia / etiology; Hypercalcemia / veterinary; Male; Phosphates / blood; Phosphates / metabolism; Radiography; Retrospective Studies; Ultrasonography; Uremia / etiology; Uremia / veterinary; Ureteral Calculi / diagnostic imaging; Ureteral Calculi / epidemiology; Ureteral Calculi / veterinary; Ureteral Obstruction / diagnostic imaging; Ureteral Obstruction / veterinary; Urinary Tract Infections / etiology; Urinary Tract Infections / veterinary
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2005 journal article

Management and outcome of cats with ureteral calculi: 153 cases (1984-2002)

JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, 226(6), 937–944.

By: A. Kyles*, E. Hardie n, B. Wooden*, C. Adin*, E. Stone n, C. Gregory*, K. Mathews n, L. Cowgill ...

MeSH headings : Animals; Cat Diseases / mortality; Cat Diseases / surgery; Cat Diseases / therapy; Cats; Female; Kidney / physiology; Male; Retrospective Studies; Treatment Outcome; Ureteral Calculi / mortality; Ureteral Calculi / surgery; Ureteral Calculi / therapy; Ureteral Calculi / veterinary; Ureteral Obstruction / mortality; Ureteral Obstruction / surgery; Ureteral Obstruction / therapy; Ureteral Obstruction / veterinary
TL;DR: Results suggest that medical and surgical management of ureteral calculi in cats are associated with high morbidity and mortality rates, but treatment can stabilize renal function, although many surviving cats will continue to have impaired renal function. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2005 journal article

Renal biopsy of dogs and cats

CLINICAL TECHNIQUES IN SMALL ANIMAL PRACTICE, 20(1), 11–22.

By: S. Vaden n

author keywords: renal biopsy; kidney biopsy; percutaneous kidney biopsy; laparoscopic kidney; biopsy; surgical kidney biopsy; complications of renal biopsy; light microscopy; electron microscopy
MeSH headings : Animals; Biopsy / instrumentation; Biopsy / methods; Biopsy / veterinary; Cat Diseases / diagnosis; Cat Diseases / pathology; Cats; Dog Diseases / diagnosis; Dog Diseases / pathology; Dogs; Kidney / pathology; Kidney Diseases / diagnosis; Kidney Diseases / pathology; Kidney Diseases / veterinary
TL;DR: The article summarizes patient selection and evaluation, renal biopsy techniques, expected complications of renal biopsies, and appropriate processing and evaluation of the renalBiopsy specimen. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2005 journal article

Renal biopsy: A retrospective study of methods and complications in 283 dogs and 65 cats

JOURNAL OF VETERINARY INTERNAL MEDICINE, 19(6), 794–801.

By: S. Vaden*, J. Levine n, G. Lees*, R. Groman*, G. Grauer* & S. Forrester*

author keywords: kidney biopsy; renal biopsy quality
TL;DR: It is concluded that renal biopsy is a relatively safe procedure, with a low frequency of severe complications, and the majority of biopsies from both dogs and cats were considered to be of satisfactory quality. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2005 article

Urinary tract manifestations of protothecosis in dogs

JOURNAL OF VETERINARY INTERNAL MEDICINE, Vol. 19, pp. 115–119.

By: B. Pressler*, J. Gookin*, J. Sykes, A. Wolf & S. Vaden*

author keywords: acute renal failure; algae; Prototheca wickerhaniii; Prototheca zopfii; urinary tract infection; urine culture
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2004 journal article

Clinical nephrology and urology

Veterinary Clinics of North America: Small Animal Practice, 34(4), xi-xii.

By: I. Lane*, S. Dru Forrester* & S. Vaden n

UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Crossref
Added: February 24, 2020

2004 journal article

Clinical nephrology and urology - Preface

Veterinary Clinics of North America. Small Animal Practice, 34(4), XI-.

By: I. Lane, S. Forrester & S. Vaden

Source: NC State University Libraries
Added: August 6, 2018

2004 article

Doppler ultrasonographic evaluation of gastrointestinal hemodynamics in food hypersensitivities: A canine model

JOURNAL OF VETERINARY INTERNAL MEDICINE, Vol. 18, pp. 605–611.

By: P. Kircher*, K. Spaulding n, S. Vaden n, J. Lang*, M. Doherr* & L. Gaschen*

author keywords: celiac artery; cranial mesenteric artery; dietary challenge; splanchnic blood flow
Source: Web Of Science
Added: August 6, 2018

2004 journal article

Effects of urinary tract inflammation and sample blood contamination on urine albumin and total protein concentrations in canine urine samples

VETERINARY CLINICAL PATHOLOGY, 33(1), 14–19.

By: S. Vaden n, B. Pressler n, M. Lappin* & W. Jensen*

author keywords: albuminuria; hematuria; microalbuminuria; proteinuria; pyuria
MeSH headings : Albuminuria / etiology; Albuminuria / urine; Albuminuria / veterinary; Animals; Creatinine / urine; Dog Diseases / diagnosis; Dog Diseases / etiology; Dog Diseases / urine; Dogs; Enzyme-Linked Immunosorbent Assay / methods; Enzyme-Linked Immunosorbent Assay / veterinary; Female; Hematuria / veterinary; Male; Osmolar Concentration; Proteinuria / etiology; Proteinuria / urine; Proteinuria / veterinary; Pyuria / complications; Pyuria / diagnosis; Pyuria / veterinary; Sensitivity and Specificity; Urinalysis / methods; Urinalysis / veterinary; Urinary Tract Infections / complications; Urinary Tract Infections / diagnosis; Urinary Tract Infections / veterinary
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2004 journal article

In vitro prediction of canine urolith mineral composition using computed tomographic mean beam attenuation measurements

Veterinary Radiology Ultrasound, 45(3), 189–197.

By: B. Pressler n, L. Mohammadian n, E. Li n, S. Vaden n, J. Levine n, K. Mathews n, I. Robertson n

author keywords: beam attenuation; calcium oxalate; computed tomography; dog; Hounsfield units; struvite; uric acid; urolith
MeSH headings : Animals; Calcium Oxalate / chemistry; Dog Diseases / diagnostic imaging; Dogs; Magnesium Compounds / chemistry; Phosphates / chemistry; Predictive Value of Tests; Sensitivity and Specificity; Struvite; Tomography, X-Ray Computed / veterinary; Uric Acid / chemistry; Urinary Calculi / chemistry; Urinary Calculi / diagnostic imaging; Urinary Calculi / veterinary
TL;DR: HU could be used to differentiate three types of uroliths of pure mineral composition in vitro and further studies are needed to determine the predictive value of HU in vivo. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, Crossref, NC State University Libraries
Added: August 6, 2018

2004 journal article

Renal biopsy: methods and interpretation

VETERINARY CLINICS OF NORTH AMERICA-SMALL ANIMAL PRACTICE, 34(4), 887-+.

By: S. Vaden n

MeSH headings : Animals; Biopsy / methods; Biopsy / veterinary; Cat Diseases / pathology; Cats; Dog Diseases / pathology; Dogs; Kidney Diseases / pathology; Kidney Diseases / veterinary
TL;DR: Renal biopsy most often is indicated in the management of dogs and cats with glomerular disease or acute renal failure and should be monitored during the post biopsy period for severe hemorrhage, the most common complication. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2004 journal article

The Clinician Investigator Program in Companion Animal Internal Medicine at North Carolina State University

Journal of Veterinary Medical Education, 31(4), 425–434.

By: S. Bunch*, R. Ford*, E. Hawkins*, M. Jackson*, S. Vaden* & E. Breitschwerdt*

MeSH headings : Animals; Animals, Domestic; Curriculum; Education, Veterinary / methods; Humans; Internal Medicine / education; Mentors; North Carolina; Research Personnel; Retrospective Studies; Schools, Veterinary; Surveys and Questionnaires
TL;DR: A retrospective study was conducted to describe the development and evolution of the combined internal medicine/PhD program, the Clinician Investigator (CI) Program, at North Carolina State University. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: NC State University Libraries, NC State University Libraries, Crossref
Added: August 6, 2018

2003 journal article

Candida spp. urinary tract infections in 13 dogs and seven cats: Predisposing factors, treatment, and outcome

JOURNAL OF THE AMERICAN ANIMAL HOSPITAL ASSOCIATION, 39(3), 263–270.

MeSH headings : Animals; Antifungal Agents / therapeutic use; Candida / classification; Candida / isolation & purification; Candida albicans / isolation & purification; Candidiasis / epidemiology; Candidiasis / veterinary; Cat Diseases / drug therapy; Cat Diseases / epidemiology; Cat Diseases / microbiology; Cat Diseases / pathology; Cat Diseases / urine; Cats; Dog Diseases / drug therapy; Dog Diseases / epidemiology; Dog Diseases / microbiology; Dog Diseases / pathology; Dog Diseases / urine; Dogs; Female; Immunocompromised Host; Male; North Carolina / epidemiology; Records / veterinary; Retrospective Studies; Treatment Outcome; Urinary Tract Infections / epidemiology; Urinary Tract Infections / veterinary
TL;DR: It is concluded that correction of predisposing conditions is likely critical for management of Candida spp. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2003 journal article

Managing renal amyloidosis in dogs and cats

Veterinary Medicine, 98(4), 320-.

By: B. Pressler & S. Vaden

Source: NC State University Libraries
Added: August 6, 2018

2003 article

Persistent urinary tract infections and reinfections in 100 dogs (1989-1999)

JOURNAL OF VETERINARY INTERNAL MEDICINE, Vol. 17, pp. 622–631.

By: M. Seguin, S. Vaden*, C. Altier*, E. Stone* & J. Levine*

author keywords: canine; chronic urinary tract infection; complicated urinary tract infection; predisposing condition; recurrent urinary tract infection; resistance
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2002 journal article

Detection of canine microalbuminuria using semiquantitative test strips designed for use with human urine

VETERINARY CLINICAL PATHOLOGY, 31(2), 56–60.

By: B. Pressler n, S. Vaden n, W. Jensen* & D. Simpson*

author keywords: Clinitek Microalbumin; dipstick; dog; microalbuminuria; urine
MeSH headings : Albuminuria / diagnosis; Albuminuria / veterinary; Animals; Dog Diseases / diagnosis; Dog Diseases / urine; Dogs; Enzyme-Linked Immunosorbent Assay / veterinary; Humans; Nephelometry and Turbidimetry / veterinary; Prospective Studies; Reagent Strips; Sensitivity and Specificity; Urinalysis / instrumentation; Urinalysis / methods; Urinalysis / veterinary; Urinary Tract Infections / diagnosis; Urinary Tract Infections / urine; Urinary Tract Infections / veterinary
TL;DR: The results suggest that the Clinitek strips lack sufficient concordance with results obtained by ELISA to be a reliable screening for test microalbuminuria in the dog. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2002 article

Fecal polymerase chain reaction with 16S ribosomal RNA primers can detect the presence of gastrointestinal Helicobacter in dogs

JOURNAL OF VETERINARY INTERNAL MEDICINE, Vol. 16, pp. 426–432.

By: J. Shinozaki, R. Sellon*, G. Cantor, T. Besser, K. Mealey & S. Vaden*

author keywords: sequence analysis; sequence homology; speciation; treatment response
Source: Web Of Science
Added: August 6, 2018

2001 chapter

Penicillins and related beta-Lactam antibiotics

In Veterinary pharmacology and therapeutics (8th ed.) (pp. 818–827). Ames, IA: Iowa State University Press.

By: S. Vaden & J. Riviere

Source: NC State University Libraries
Added: August 6, 2018

2000 chapter

Differentiation of acute from chronic renal failure

In Kirk's current veterinary therapy : small animal practice (13th Ed.) (p. 856). Philadelphia, PA : W.B. Saunders.

By: S. Vaden

Source: NC State University Libraries
Added: August 6, 2018

2000 article

Effects of enalapril versus placebo as a treatment for canine idiopathic glomerulonephritis

JOURNAL OF VETERINARY INTERNAL MEDICINE, Vol. 14, pp. 526–533.

By: G. Grauer, D. Greco, D. Getzy, L. Cowgill, S. Vaden*, D. Chew, D. Polzin, J. Barsanti

author keywords: angiotensin-converting enzyme inhibition; kidney; renal
TL;DR: It is suggested that EN treatment is beneficial in dogs with naturally occurring idiopathic glomerulonephritis, and response to treatment was significantly better in the EN group compared with the placebo group. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2000 article

Evaluation of intestinal permeability and gluten sensitivity in Soft-Coated Wheaten Terriers with familial protein-losing enteropathy, protein-losing nephropathy, or both

Vaden, S. L., Sellon, R. K., Melgarejo, L. T., Williams, D. A., Trogdon, M. M., VanCamp, S. D., & Argenzio, R. A. (2000, May). AMERICAN JOURNAL OF VETERINARY RESEARCH, Vol. 61, pp. 518–524.

By: S. Vaden n, R. Sellon n, L. Melgarejo n, D. Williams n, M. Trogdon n, S. VanCamp n, R. Argenzio n

MeSH headings : Animals; Biopsy / veterinary; Blood Cell Count / veterinary; Chlorides / pharmacology; Chlorides / urine; Chromium Compounds / pharmacology; Chromium Compounds / urine; Creatinine / urine; Dog Diseases / genetics; Dog Diseases / pathology; Dog Diseases / physiopathology; Dogs; Duodenum / pathology; Duodenum / physiopathology; Feces / chemistry; Female; Food Hypersensitivity / etiology; Food Hypersensitivity / physiopathology; Food Hypersensitivity / veterinary; Glutens / immunology; Glutens / metabolism; Kidney Diseases / genetics; Kidney Diseases / physiopathology; Kidney Diseases / veterinary; Male; Permeability; Protein-Losing Enteropathies / genetics; Protein-Losing Enteropathies / physiopathology; Protein-Losing Enteropathies / veterinary; Serum Albumin / analysis; Serum Globulins / analysis; Spectrophotometry, Atomic / veterinary; Statistics, Nonparametric; alpha 1-Antitrypsin / analysis
TL;DR: Although enhanced wheat-gluten sensitivity may be one factor involved in the pathogenesis of PLE or PLN in SCWT, this syndrome does not appear to be the result of a specific sensitivity to gluten. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2000 journal article

Familial protein-losing enteropathy and protein-losing nephropathy in Soft Coated Wheaten Terriers: 222 cases (1983-1997)

JOURNAL OF VETERINARY INTERNAL MEDICINE, 14(1), 68–80.

By: M. Littman, D. Dambach, S. Vaden* & U. Giger

author keywords: glomerulonephritis; inflammatory bowel disease; lymphangiectasia; lymphangitis
TL;DR: A new, distinctive familial predisposition for both PLE and PLN has been recognized in the SCWT breed, and the prognosis is poor. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2000 article

Food hypersensitivity reactions in Soft Coated Wheaten Terriers with protein-losing enteropathy or protein-losing nephropathy or both: Gastroscopic food sensitivity testing, dietary provocation, and fecal immunoglobulin E

JOURNAL OF VETERINARY INTERNAL MEDICINE, Vol. 14, pp. 60–67.

By: S. Vaden n, B. Hammerberg n, D. Davenport, S. Orton n, M. Trogdon n, L. Melgarejo*, S. VanCamp n, D. Williams*

author keywords: food allergy; glomerulonephritis; inflammatory bowel disease
Source: Web Of Science
Added: August 6, 2018

2000 journal article

Hypercalcemia in cats: A retrospective study of 71 cases (1991-1997)

JOURNAL OF VETERINARY INTERNAL MEDICINE, 14(2), 184–189.

By: K. Savary, G. Price & S. Vaden*

author keywords: calcium; calcium oxalate urolithiasis; neoplasia; primary hyperparathyroidism; renal failure
TL;DR: A retrospective study to characterize the diseases, clinical findings, and clinicopathologic and ultrasonographic findings associated with hypercalcemia in 71 cats presented to North Carolina State University Veterinary Teaching Hospital found that the majority of cats with uroliths were azotemic, their serum urea nitrogen and creatinine concentrations and urine specific gravity differed from that of Cats with renal failure. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

1998 journal article

Evaluation of urine protein content in dogs with pituitary-dependent hyperadrenocorticism

Journal of the American Veterinary Medical Association, 212(3), 369–373.

By: K. Hurley & S. Vaden

Source: NC State University Libraries
Added: August 6, 2018

1998 journal article

Modulation of doxorubicin concentration by cyclosporin A in brain and testicular barrier tissues expressing P-glycoprotein in rats

JOURNAL OF NEURO-ONCOLOGY, 37(1), 45–54.

By: C. Hughes n, S. Vaden n, C. Manaugh n, G. Price n & L. Hudson n

author keywords: cyclosporin A; blood-tissue barrier; P-glycoprotein; multidrug resistance; doxorubicin; cisplatin
MeSH headings : ATP Binding Cassette Transporter, Subfamily B, Member 1 / biosynthesis; Animals; Blood-Brain Barrier / drug effects; Brain / drug effects; Brain / metabolism; Cisplatin / administration & dosage; Cisplatin / pharmacology; Cyclosporine / administration & dosage; Cyclosporine / pharmacology; Doxorubicin / pharmacokinetics; Evans Blue / pharmacokinetics; Fluorescein / pharmacokinetics; Horseradish Peroxidase / pharmacokinetics; Injections, Intravenous; Injections, Subcutaneous; Male; Platinum / pharmacokinetics; Rats; Rats, Inbred F344; Testis / drug effects; Testis / metabolism; Tissue Distribution / drug effects
TL;DR: Modulation of Pgp function may prove to be useful for improving chemotherapy efficacy for patients with malignancies affecting tissues with blood-tissue barriers. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

1997 journal article

A Retrospective Case-Control of Acute Renal Failure in 99 Dogs

Journal of Veterinary Internal Medicine, 11(2), 58–64.

By: S. Vaden n, J. Levine n & E. Breitschwerdt n

MeSH headings : Acute Kidney Injury / diagnosis; Acute Kidney Injury / epidemiology; Acute Kidney Injury / etiology; Acute Kidney Injury / veterinary; Animals; Case-Control Studies; Creatinine / blood; Demography; Dog Diseases / diagnosis; Dog Diseases / epidemiology; Dog Diseases / etiology; Dogs; Female; Logistic Models; Male; Retrospective Studies; Risk Factors; Seasons; Treatment Failure
TL;DR: Intact male dogs and nonsporting dogs were more likely to develop ARF and be admitted to the teaching hospital and dogs that survived in the hospital for more than 5 days were morelikely to recover and be discharged from the hospital. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

1997 journal article

Auto IgG anti-IgE and IgG x IgE immune complex presence and effects on ELISA-based quantitation of IgE in canine atopic dermatitis, demodectic acariasis and helminthiasis.

VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 60(1-2), 33–46.

By: B. Hammerberg n, D. Bevier n, D. DeBoer*, T. Olivry n, S. Orton n, D. Gebhard n, S. Vaden n

Contributors: B. Hammerberg n, D. Bevier n, D. DeBoer*, T. Olivry n, S. Orton n, D. Gebhard n, S. Vaden n

author keywords: auto anti-IgE; ELISA; atopic; helminth; immune complexes; demodectic acariasis
MeSH headings : Animals; Antibodies, Anti-Idiotypic / blood; Antigen-Antibody Complex / blood; Ascariasis / immunology; Ascariasis / veterinary; Autoantibodies / blood; Dermatitis, Atopic / immunology; Dermatitis, Atopic / veterinary; Dog Diseases / immunology; Dogs; Enzyme-Linked Immunosorbent Assay; Helminthiasis, Animal / immunology; Immunoglobulin E / blood; Immunoglobulin G / blood
TL;DR: The increase in detectable IgG anti-IgE after heating sera indicates that IgG x IgE immune complexes are normally present in most dogs; however, the increase over uncomplexed IgG against IgE was most pronounced in dogs manifesting atopic dermatitis and demodectic acariasis. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

1997 journal article

Cyclosporine and tacrolimus

SEMINARS IN VETERINARY MEDICINE AND SURGERY-SMALL ANIMAL, 12(3), 161–166.

By: S. Vaden n

MeSH headings : Animals; Autoimmune Diseases / drug therapy; Autoimmune Diseases / veterinary; Cat Diseases / drug therapy; Cats; Cyclosporine / adverse effects; Cyclosporine / pharmacokinetics; Cyclosporine / therapeutic use; Dog Diseases / drug therapy; Dogs; Dose-Response Relationship, Drug; Drug Interactions; Eye Diseases / drug therapy; Eye Diseases / veterinary; Glomerulonephritis / drug therapy; Glomerulonephritis / veterinary; Graft Rejection / drug therapy; Graft Rejection / veterinary; Immunosuppressive Agents / adverse effects; Immunosuppressive Agents / pharmacokinetics; Immunosuppressive Agents / therapeutic use; Skin Diseases / drug therapy; Skin Diseases / veterinary; Tacrolimus / adverse effects; Tacrolimus / pharmacokinetics; Tacrolimus / therapeutic use; Transplantation / methods; Transplantation / veterinary
TL;DR: The mechanism of action, pharmacokinetics, expected drug interactions and toxicities, and clinical usage of cyclosporine and tacrolimus in veterinary medicine are reviewed. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

1997 journal article

Fluconazole in cats: Pharmacokinetics following intravenous and oral administration and penetration into cerebrospinal fluid, aqueous humour and pulmonary epithelial lining fluid

Journal of Veterinary Pharmacology and Therapeutics, 20(3), 181–186.

By: S. Vaden*, M. Heit, E. Hawkins*, C. Manaugh & J. Riviere n

MeSH headings : Administration, Oral; Animals; Antifungal Agents / administration & dosage; Antifungal Agents / cerebrospinal fluid; Antifungal Agents / pharmacokinetics; Area Under Curve; Biological Availability; Cats; Chromatography, High Pressure Liquid; Cross-Over Studies; Epithelium / metabolism; Fluconazole / administration & dosage; Fluconazole / cerebrospinal fluid; Fluconazole / pharmacokinetics; Half-Life; Injections, Intravenous; Intestinal Absorption; Lung / metabolism; Male; Random Allocation
TL;DR: Results of this study suggest fluconazole can effectively be administered to cats at 50 mg per cat per day, as suggested by non-compartmental analysis of data. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

1997 journal article

Pharmacokinetics of enrofloxacin in the red pacu (Colossoma brachypomum) after intramuscular, oral and bath administration

JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS, 20(2), 124–128.

By: G. Lewbart n, S. Vaden n, J. Deen n, C. Manaugh n, D. Whitt n, A. Doi n, T. Smith n, K. Flammer n

MeSH headings : Administration, Oral; Animals; Anti-Infective Agents / administration & dosage; Anti-Infective Agents / blood; Anti-Infective Agents / pharmacokinetics; Area Under Curve; Enrofloxacin; Fishes / blood; Fluoroquinolones; Half-Life; Injections, Intramuscular; Models, Biological; Quinolones / administration & dosage; Quinolones / blood; Quinolones / pharmacokinetics
TL;DR: The intramuscular, oral, and bath immersion disposition of enrofloxacin were evaluated following administration to a cultured population of red pacu, finding the i.m. route is the most predictable and results in the highest plasma concentrations of the drug. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

1997 journal article

Use of carbamylated hemoglobin concentration to differentiate acute from chronic renal failure in dogs

American Journal of Veterinary Research, 58(11), 1193–1196.

By: S. Vaden, J. Gookin, M. Trogdon, C. Langston, J. Levine & L. Cowgill

Source: NC State University Libraries
Added: August 6, 2018

1996 journal article

Acute Tubulointerstitial Nephritis With Eosinophiluria in a Dog

Journal of Veterinary Internal Medicine, 10(1), 45–47.

By: M. Hadrick n, S. Vaden n, F. Geoly n, J. Cullen n & J. Douglass n

MeSH headings : Acute Disease; Animals; Biopsy / veterinary; Blood Urea Nitrogen; Creatinine / blood; Dog Diseases / blood; Dog Diseases / diagnosis; Dog Diseases / pathology; Dogs; Eosinophilia / diagnosis; Eosinophilia / pathology; Eosinophilia / veterinary; Eosinophils / pathology; Female; Kidney / pathology; Leukocytosis / diagnosis; Leukocytosis / pathology; Leukocytosis / veterinary; Nephritis, Interstitial / blood; Nephritis, Interstitial / diagnosis; Nephritis, Interstitial / veterinary; Neutrophils / pathology; Urine / cytology
Sources: Crossref, Web Of Science
Added: August 6, 2018

1996 journal article

An in vitro-in vivo validation of the isolated perfused tumor and skin flap preparation as a model of cisplatin delivery to tumors

JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS, 35(3), 173–177.

By: S. Vaden n, R. Page n & J. Riviere n

author keywords: cisplatin; isolated perfused tumor and skin flap; isolated perfusion
MeSH headings : Animals; Antineoplastic Agents / administration & dosage; Antineoplastic Agents / pharmacokinetics; Chemotherapy, Cancer, Regional Perfusion / methods; Cisplatin / administration & dosage; Cisplatin / pharmacokinetics; Drug Screening Assays, Antitumor; In Vitro Techniques; Injections, Intralesional; Neoplasms, Experimental / drug therapy; Neoplasms, Experimental / metabolism; Reproducibility of Results; Surgical Flaps; Swine
TL;DR: Tissue Pt concentrations obtained following systemic administration of cisplatin (CDDP) to whole pigs bearing tumored skin flaps with data obtained from IPTSF treated similarly are compared to that obtained in vivo. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

1996 journal article

Management and complications following trigonal-colonic anastomosis in a dog: five-year evaluation

Journal of the American Animal Hospital Association, 32(1), 29–35.

By: J. Smith*, S. Vaden*, E. Stone, K. Spaulding & R. Miller

MeSH headings : Anastomosis, Surgical / adverse effects; Anastomosis, Surgical / standards; Anastomosis, Surgical / veterinary; Animals; Colon / surgery; Diagnosis, Differential; Dog Diseases / diagnosis; Dog Diseases / surgery; Dogs; Female; Follow-Up Studies; Urethritis / diagnosis; Urethritis / surgery; Urethritis / veterinary
TL;DR: A case managed for five years following trigonal-colonic anastomosis for lymphocytic-plasmacytic urethritis is presented, along with a review of urinary diversion techniques, and postoperative management recommendations following urinary diversion are discussed. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Crossref, Web Of Science
Added: August 6, 2018

1996 journal article

Vestibulovaginal stenosis in dogs: 18 cases (1987-1995)

Journal of the American Veterinary Medical Association, 209(11), 1889–1893.

By: A. Kyles, S. Vaden, L. Hardie & E. Stone

Source: NC State University Libraries
Added: September 18, 2021

1995 journal article

Adrenalectomy for the treatment of hyperadrenocorticism in cats: 10 cases (1988-1992)

Journal of the American Veterinary Medical Association, 207(8), 1066–1070.

By: C. Duesberg, R. Nelson, E. Feldman, S. Vaden & J. Scott-Moncrieff

Source: NC State University Libraries
Added: September 18, 2021

1995 chapter

Drug therapy during renal disease and renal failure

In Canine and feline nephrology and urology (pp. 555–572). Baltimore: Williams and Wilkins.

By: J. Riviere & S. Vaden

Source: NC State University Libraries
Added: August 6, 2018

1995 chapter

Penicillins and related beta-Lactam antibiotics

In Veterinary pharmacology and therapeutics (7th ed.) (pp. 774–783). Ames: Iowa State University Press.

By: S. Vaden & J. Riviere

Source: NC State University Libraries
Added: August 6, 2018

1995 journal article

Pharmacokinetics of cyclosporine in woodchucks and Pekin ducks

Journal of Veterinary Pharmacology and Therapeutics, 18(1), 30–33.

By: S. Vaden n, J. Cullen n & J. Riviere n

MeSH headings : Animals; Antibodies, Monoclonal; Antibody Specificity; Cyclosporine / administration & dosage; Cyclosporine / blood; Cyclosporine / pharmacokinetics; Ducks / metabolism; Immunosuppression Therapy / veterinary; Injections, Intravenous / veterinary; Marmota / metabolism; Radioimmunoassay / veterinary; Regression Analysis; Species Specificity
TL;DR: The pharmacokinetic data suggest that Pekin ducks clear Cy at a faster rate than do woodchucks and that a greater dose of Cy should be administered to PekIn ducks in order to achieve adequate immunosuppression. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, Crossref
Added: August 6, 2018

1995 journal article

Relationship between plasma creatinine concentration and glomerular filtration rate in dogs

Journal of Veterinary Pharmacology and Therapeutics, 18(6), 418–421.

By: D. Finco*, S. Brown*, S. Vaden n & D. Ferguson n

MeSH headings : Animals; Blood Urea Nitrogen; Confidence Intervals; Creatinine / blood; Dogs / blood; Dogs / physiology; Female; Glomerular Filtration Rate / physiology; Glomerular Filtration Rate / veterinary; Kidney / physiopathology; Male; Nephrectomy / veterinary; Organ Size / physiology; Regression Analysis
TL;DR: The regression equation and the confidence intervals generated in this study may be used to predict a probable range of GFR values from CR in individual dogs and may be useful in adjusting drug dosages in dogs with renal disease. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Crossref
Added: July 20, 2019

1995 journal article

Splenic Infarction in 16 Dogs: A Retrospective Study

Journal of Veterinary Internal Medicine, 9(3), 141–148.

By: E. Hardie n, S. Vaden n, K. Spaulding n & D. Malarkey n

MeSH headings : Animals; Body Temperature; Dog Diseases / blood; Dog Diseases / physiopathology; Dogs; Female; Heart Rate; Male; Retrospective Studies; Splenic Infarction / blood; Splenic Infarction / diagnostic imaging; Splenic Infarction / physiopathology; Splenic Infarction / veterinary; Thrombosis / veterinary; Ultrasonography
TL;DR: Splenic infaraction should be regarded as a sign of altered blood flow and coagulation, rather than as a primary disease, and surgical management should be reserved for patients with life-threatening complications such as hemoabdomen or sepsis. (via Semantic Scholar)
Sources: Crossref, Web Of Science
Added: August 6, 2018

1995 journal article

The Effects of Cyclosporine Versus Standard Care in Dogs With Naturally Occurring Glomerulonephritis

Journal of Veterinary Internal Medicine, 9(4), 259–266.

By: S. Vaden n, E. Breitschwerdt n, P. Armstrong*, M. Correa n, C. Brown*, D. Polzin*, J. Brace*, S. DiBartola* ...

MeSH headings : Animals; Antigen-Antibody Complex / analysis; Cyclosporine / adverse effects; Cyclosporine / therapeutic use; Dog Diseases / drug therapy; Dog Diseases / mortality; Dogs; Drug Tolerance; Female; Gingival Hyperplasia / chemically induced; Glomerulonephritis / drug therapy; Glomerulonephritis / mortality; Glomerulonephritis / veterinary; Immunosuppressive Agents / adverse effects; Immunosuppressive Agents / therapeutic use; Male; Survival Rate; Treatment Outcome
TL;DR: The effects of cyclosporine (Cy) administration on the outcome of naturally occurring GN in dogs were determined and decreased appetite, diarrhea, vomiting, weight loss, involuntary shaking, and thrombocytopenia were noted in both treatment groups; however, clinical signs in Cy-treated dogs subjectively were more severe. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: July 20, 2019

1994 journal article

Cerebrospinal fluid collection in rats: modification of a previous technique

Laboratory Animal Science, 44(4), 358–361.

By: L. Hudson, C. Hughes, N. Bold-Fletcher & S. Vaden

Source: NC State University Libraries
Added: September 18, 2021

1994 journal article

EFFECT OF HYPERTHERMIA ON CISPLATIN AND CARBOPLATIN DISPOSITION IN THE ISOLATED, PERFUSED TUMOR AND SKIN FLAP

INTERNATIONAL JOURNAL OF HYPERTHERMIA, 10(4), 563–572.

By: S. Vaden n, R. Page n, P. Williams n & J. Riviere n

author keywords: CISPLATIN; CARBOPLATIN; HYPERTHERMIA; ISOLATED TUMOR PERFUSION
MeSH headings : Animals; Body Temperature Regulation; Carboplatin / administration & dosage; Carboplatin / pharmacokinetics; Cisplatin / administration & dosage; Cisplatin / pharmacokinetics; Combined Modality Therapy; Hyperthermia, Induced; In Vitro Techniques; Neoplasms, Experimental / drug therapy; Neoplasms, Experimental / physiopathology; Neoplasms, Experimental / therapy; Perfusion; Platinum / pharmacokinetics; Surgical Flaps; Swine
TL;DR: Hyperthermia (HT) alters the disposition of Pt from CDDP and CBDCA under conditions of constant rate infusion, and significantly increased Pt mass in the fixed, non-tumour tissue compartment of CBDCA-treated flaps. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

1993 chapter

Antimicrobial prophylaxis

In Disease mechanisms in small animal surgery (pp. 66–69). Philadelphia: Lea and Febiger.

By: J. Riviere & S. Vaden

Source: NC State University Libraries
Added: August 6, 2018

1993 journal article

Development and characterization of an isolated and perfused tumor and skin preparation for evaluation of drug disposition

Cancer Research, 53, 101–105.

By: S. Vaden, R. Page, B. Peters, J. Cline & J. Riviere

Source: NC State University Libraries
Added: August 6, 2018

1993 journal article

EFFECT OF TUMOR PRESENCE ON CISPLATIN AND CARBOPLATIN - DISPOSITION IN THE ISOLATED, PERFUSED TUMOR AND SKIN FLAP

CANCER CHEMOTHERAPY AND PHARMACOLOGY, 32(1), 31–38.

By: S. Vaden n, P. Williams n, R. Page n & J. Riviere n

author keywords: CISPLATIN; CARBOPLATIN; ISOLATED TUMOR PERFUSION
MeSH headings : Animals; Carboplatin / administration & dosage; Carboplatin / pharmacokinetics; Chemotherapy, Cancer, Regional Perfusion / instrumentation; Choriocarcinoma; Cisplatin / administration & dosage; Cisplatin / pharmacokinetics; Humans; Models, Biological; Platinum / analysis; Skin / metabolism; Swine; Tumor Cells, Cultured / metabolism; Vascular Resistance
TL;DR: It is concluded that the IPTSF is a useful model for evaluating the disposition of Pt drugs in tumor and non-tumor tissue and that tumor presence alters the disposing of CDDP. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

1992 journal article

Cobalamin deficiency associated with methylmalonic acidemia in a cat

Journal of the American Veterinary Medical Association, 200(8), 1101.

By: S. Vaden, P. Wood, F. Ledley, P. Cornwell, R. Miller & R. Page

Source: NC State University Libraries
Added: August 6, 2018

1991 journal article

Primary ciliary dyskinesia in Bichon Frise litter mates

Journal of the American Animal Hospital Association, 27(6), 633.

By: S. Vaden, E. Breitschwerdt, C. Henrikson, M. Metcalf, L. Cohn & W. Craig

Source: NC State University Libraries
Added: August 6, 2018

1990 journal article

Comparative pharmacokinetics of doxycycline in cats and dogs

Journal of Veterinary Pharmacology and Therapeutics, 13(4), 415–424.

By: J. Riond n, S. Vaden n & J. Riviere n

MeSH headings : Animals; Cats / metabolism; Dogs / metabolism; Doxycycline / administration & dosage; Doxycycline / pharmacokinetics; Female; Half-Life; Injections, Intravenous / veterinary; Tissue Distribution
TL;DR: The disposition of doxycycline hyclate was studied in six adult mixed-breed female cats and six adult mid-sized female dogs following a single intravenous administration of 5 mg/kg body weight. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Crossref, Web Of Science
Added: August 6, 2018

1990 journal article

Glomerulonephritis

Kal Kan Forum, 9(4), 3.

By: S. Vaden

Source: NC State University Libraries
Added: August 6, 2018

1990 journal article

Isolated perfused tumored skin flap model

Veterinary Cancer Society Newsletter, 14, 1–6.

By: S. Vaden & J. Riviere

Source: NC State University Libraries
Added: August 6, 2018

1990 journal article

Pharmacokinetics, inhibition of lymphoblast transformation and subacute oral toxicity of cyclosporine in swine

American Journal of Veterinary Research, 51, 399–403.

By: S. Vaden & J. Riviere

Source: NC State University Libraries
Added: August 6, 2018

1988 journal article

Hepatotoxicosis associated with heartworm/hookworm preventative medication in a dog

Journal of the American Veterinary Medical Association, 192(5), 651–654.

By: S. Vaden, S. Bunch, D. Duncan & J. Cullen

Source: NC State University Libraries
Added: September 18, 2021

1985 journal article

Inotropic, chronotropic and coronary vasodilator potency of forskolin

European Journal of Pharmacology, 118(1-2), 131–137.

By: S. Vaden* & H. Adams*

MeSH headings : Adenylyl Cyclases / metabolism; Animals; Colforsin / pharmacology; Coronary Circulation / drug effects; Cyclic AMP / metabolism; Dose-Response Relationship, Drug; Guinea Pigs; Heart Rate / drug effects; In Vitro Techniques; Isoproterenol / pharmacology; Male; Myocardial Contraction / drug effects; Potassium / pharmacology; Vascular Resistance / drug effects; Vasodilation / drug effects
TL;DR: It is concluded that forskolin induces direct pharmacologic effects in ventricular muscle, pacemaker cells and the coronary vasculature, but it is added that the coronary Vasculature is over one order of magnitude more sensitive to forSkolin than isventricular muscle. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: Crossref
Added: July 20, 2019

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