Works (93)

Updated: December 3rd, 2023 05:00

2023 journal article

A vision for safer food contact materials: Public health concerns as drivers for improved testing

ENVIRONMENT INTERNATIONAL, 180.

By: J. Muncke*, A. Andersson*, T. Backhaus*, S. Belcher n, J. Boucher*, B. Almroth*, T. Collins*, B. Geueke* ...

co-author countries: Switzerland 🇨🇭 Denmark 🇩🇰 Spain 🇪🇸 France 🇫🇷 United Kingdom of Great Britain and Northern Ireland 🇬🇧 Netherlands 🇳🇱 Sweden 🇸🇪 United States of America 🇺🇸
author keywords: Food packaging; Hazard assessment; Chronic disease; Chemical safety
Sources: ORCID, Web Of Science
Added: September 26, 2023

2023 article

Assessing Per- and Polyfluoroalkyl Substances (PFAS) in Fish Fillet Using Non-Targeted Analyses

Boatman, A. K., Chappel, J. R., Polera, M. E., Dodds, J. N., Belcher, S. M., & Baker, E. S. (2023, September 5).

co-author countries: United States of America 🇺🇸
Source: ORCID
Added: September 6, 2023

2023 journal article

Domestic Dogs and Horses as Sentinels of Per- and Polyfluoroalkyl Substance Exposure and Associated Health Biomarkers in Gray's Creek North Carolina

ENVIRONMENTAL SCIENCE & TECHNOLOGY, 57(26), 9567–9579.

By: K. Rock n, M. Polera n, T. Guillette*, H. Starnes n, K. Dean, M. Watters, D. Stevens-Stewart, S. Belcher n

co-author countries: United States of America 🇺🇸
author keywords: canine; drinking water; equine; fluoroether; One Health; nafion by-product 2; GenX chemicals; PFOA; PFOS
Sources: ORCID, Web Of Science
Added: June 21, 2023

2022 journal article

A Critical Review and Meta-Analysis of Impacts of Per- and Polyfluorinated Substances on the Brain and Behavior

Frontiers in Toxicology, 4.

By: H. Starnes n, K. Rock n, T. Jackson n & S. Belcher n

co-author countries: United States of America 🇺🇸
Source: ORCID
Added: January 6, 2023

2022 journal article

Blood concentrations of per- and polyfluoroalkyl substances are associated with autoimmune-like effects in American alligators from Wilmington, North Carolina

FRONTIERS IN TOXICOLOGY, 4.

By: T. Guillette n, T. Jackson n, M. Guillette n, J. McCord* & S. Belcher n

co-author countries: United States of America 🇺🇸
author keywords: autoantibodies; autoimmune; crocodilian; immune toxicity; lupus; one health; PFAS
Sources: ORCID, Web Of Science
Added: January 6, 2023

2022 article

Comparative assessment of blood mercury in American alligators (Alligator mississippiensis) from Coastal North Carolina and Florida

Belcher, S. M., Guillette, M. P., Robb, F., & Rock, K. D. (2022, August 3). ECOTOXICOLOGY, Vol. 8.

By: S. Belcher n, M. Guillette n, F. Robb* & K. Rock n

co-author countries: United States of America 🇺🇸
author keywords: Bioaccumulation; Biomonitoring; Ecotoxicology; Mercury; Metals; Reptile
MeSH headings : Alligators and Crocodiles; Animals; Ecosystem; Environmental Monitoring; Florida; Humans; Mercury / analysis; North Carolina
Sources: ORCID, Web Of Science
Added: August 3, 2022

2022 article

Gestational Cd Exposure in the CD-1 Mouse Sex-Specifically Disrupts Essential Metal Ion Homeostasis

Jackson, T. W., Baars, O., & Belcher, S. M. (2022, February 25). TOXICOLOGICAL SCIENCES, Vol. 2.

By: T. Jackson n, O. Baars n & S. Belcher n

co-author countries: United States of America 🇺🇸
author keywords: gestation; epigenetic; essential metals; metallothionein; placenta
MeSH headings : Animals; Cadmium / toxicity; Cation Transport Proteins / genetics; Cation Transport Proteins / metabolism; Female; Homeostasis; Iron / metabolism; Liver / metabolism; Male; Manganese / metabolism; Manganese / toxicity; Metallothionein / genetics; Metallothionein / metabolism; Mice; Placenta / metabolism; Pregnancy; Zinc / toxicity
Sources: ORCID, Web Of Science
Added: February 26, 2022

2022 article

The imprinted gene Zac1 regulates steatosis in developmental cadmium-induced nonalcoholic fatty liver disease

Riegl, S. D., Starnes, C., Jima, D. D., Baptissart, M., Diehl, A. M., Belcher, S. M., & Cowley, M. (2022, October 6). TOXICOLOGICAL SCIENCES, Vol. 10.

By: S. Riegl n, C. Starnes n, D. Jima n, M. Baptissart n, A. Diehl*, S. Belcher n, M. Cowley n

co-author countries: United States of America 🇺🇸
author keywords: nonalcoholic fatty liver disease; developmental toxicology; epigenetics; cadmium; genomic imprinting; developmental programming
MeSH headings : Mice; Animals; Non-alcoholic Fatty Liver Disease / genetics; Non-alcoholic Fatty Liver Disease / metabolism; Cadmium; Cadmium Chloride / toxicity; PPAR gamma; Liver / metabolism; Fibrosis
Sources: ORCID, Web Of Science
Added: October 29, 2022

2022 journal article

Utilizing Pine Needles to Temporally and Spatially Profile Per- and Polyfluoroalkyl Substances (PFAS)

ENVIRONMENTAL SCIENCE & TECHNOLOGY, 56(6), 3441–3451.

By: K. Kirkwood n, J. Fleming n, H. Nguyen n, D. Reif n, E. Baker n & S. Belcher n

co-author countries: United States of America 🇺🇸
author keywords: Biomonitoring; contamination; per- and polyfluoroalkyl substances; fluoroethers; ion mobility; mass spectrometry; PFAS
MeSH headings : Alkanesulfonic Acids / analysis; Chromatography, Liquid; Fluorocarbons / analysis; United States; United States Environmental Protection Agency
Sources: ORCID, Web Of Science
Added: February 18, 2022

2021 article

Gestational Cd Exposure in the CD-1 Mouse Sex-Specifically Disrupts Essential Metal Ion Homeostasis

Jackson, T. W., Baars, O., & Belcher, S. M. (2021, November 7). (Vol. 11). Vol. 11.

By: T. Jackson n, O. Baars n & S. Belcher n

co-author countries: United States of America 🇺🇸
Source: ORCID
Added: November 8, 2021

2021 journal article

Key Characteristics of Cardiovascular Toxicants

ENVIRONMENTAL HEALTH PERSPECTIVES, 129(9).

By: L. Lind, J. Araujo*, A. Barchowsky*, S. Belcher n, B. Berridge*, N. Chiamvimonvat*, W. Chiu*, V. Cogliano* ...

co-author countries: United States of America 🇺🇸
MeSH headings : Air Pollutants / analysis; Air Pollution / analysis; Carcinogens; Environmental Pollutants / toxicity; Hazardous Substances / toxicity; Particulate Matter / analysis
Sources: Web Of Science, ORCID
Added: November 8, 2021

2021 journal article

Rapid Characterization of Human Serum Albumin Binding for Per- and Polyfluoroalkyl Substances Using Differential Scanning Fluorimetry

ENVIRONMENTAL SCIENCE & TECHNOLOGY, 55(18), 12291–12301.

By: T. Jackson n, C. Scheibly n, M. Polera n & S. Belcher n

co-author countries: United States of America 🇺🇸
author keywords: alcohols; carboxylic acids; fluorocarbons; perfluorocarbons; protein; sulfonic acids; telomer; thermal stability; toxicokinetic
MeSH headings : Alkanesulfonic Acids; Carboxylic Acids; Fluorocarbons; Fluorometry; Humans; Serum Albumin, Human; Sulfonic Acids
Sources: ORCID, Web Of Science
Added: September 9, 2021

2021 article

Utilizing Pine Needles to Temporally and Spatially Profile Per- and Polyfluoroalkyl Substances

Kirkwood, K. I., Fleming, J., Nguyen, H., Reif, D. M., Baker, E. S., & Belcher, S. M. (2021, August 26). (Vol. 8). Vol. 8.

By: K. Kirkwood n, J. Fleming n, H. Nguyen n, D. Reif n, E. Baker n & S. Belcher n

co-author countries: United States of America 🇺🇸
Source: ORCID
Added: August 27, 2021

2020 journal article

Data integration, analysis, and interpretation of eight academic CLARITY-BPA studies

REPRODUCTIVE TOXICOLOGY, 98, 29–60.

By: J. Heindel*, S. Belcher n, J. Flaws*, G. Prins*, S. Ho*, J. Mao*, H. Patisaul n, W. Ricke* ...

co-author countries: United States of America 🇺🇸

Contributors: J. Heindel*, S. Belcher n, J. Flaws*, G. Prins*, S. Ho*, J. Mao*, H. Patisaul n, W. Ricke* ...

author keywords: CLARITY-BPA; Guideline study; Bisphenol A; EDC; Endocrine disruptor; GLP; Systemic effects
MeSH headings : Animals; Behavior, Animal / drug effects; Benzhydryl Compounds / toxicity; DNA Methylation; Endocrine Disruptors / toxicity; Female; Gene Expression Regulation, Developmental / drug effects; Heart / drug effects; Heart / growth & development; Male; Mammary Glands, Animal / drug effects; Mammary Glands, Animal / growth & development; Maternal-Fetal Exchange; Ovary / drug effects; Ovary / growth & development; Phenols / toxicity; Pregnancy; Prenatal Exposure Delayed Effects / chemically induced; Prenatal Exposure Delayed Effects / genetics; Prostate / drug effects; Prostate / growth & development; Rats, Sprague-Dawley; Reproducibility of Results; Thyroid Gland / drug effects; Thyroid Gland / growth & development; Urethra / drug effects; Urethra / growth & development
Sources: Web Of Science, ORCID
Added: January 19, 2021

2020 journal article

Elevated levels of per- and polyfluoroalkyl substances in Cape Fear River Striped Bass (Morone saxatilis) are associated with biomarkers of altered immune and liver function

ENVIRONMENT INTERNATIONAL, 136.

By: T. Guillette n, J. McCord*, M. Guillette n, M. Polera n, K. Rachels*, C. Morgeson*, N. Kotlarz n, D. Knappe n ...

co-author countries: United States of America 🇺🇸

Contributors: T. Guillette n, J. McCord*, M. Guillette n, M. Polera n, K. Rachels*, C. Morgeson*, N. Kotlarz n, D. Knappe n ...

MeSH headings : Animals; Bass; Biomarkers; Fluorocarbons / toxicity; Liver; Rivers; Water Pollutants, Chemical / toxicity
Sources: Web Of Science, ORCID
Added: March 2, 2020

2020 journal article

Gestational Cd Exposure in the CD-1 Mouse Induces Sex-Specific Hepatic Insulin Insensitivity, Obesity, and Metabolic Syndrome in Adult Female Offspring

TOXICOLOGICAL SCIENCES, 178(2), 264–280.

By: T. Jackson n, G. Ryherd n, C. Scheibly n, A. Sasser n, T. Guillette n & S. Belcher n

co-author countries: United States of America 🇺🇸

Contributors: T. Jackson n, G. Ryherd n, C. Scheibly n, A. Sasser n, T. Guillette n & S. Belcher n

author keywords: cadmium; diabetes mellitus type 2; endocrine disruption; insulin resistance; metabolic; nonalcoholic fatty liver disease; retinoic acid
MeSH headings : Animals; Cadmium / toxicity; Cadmium Chloride / toxicity; Diabetes Mellitus, Type 2 / chemically induced; Female; Insulin Resistance; Liver / physiopathology; Male; Metabolic Syndrome / chemically induced; Mice; Obesity / chemically induced; Pregnancy; Prenatal Exposure Delayed Effects; Sex Factors
Sources: Web Of Science, ORCID
Added: February 15, 2021

2020 article

Heterozygous mutation of Sonic Hedgehog receptor (Ptch) drives cerebellar overgrowth and sex-specifically alters hippocampal and cortical layer structure, activity, and social behavior in female mice

Jackson, T. W., Bendfeldt, G. A., Beam, K. A., Rock, K. D., & Belcher, S. M. (2020, January 25). (Vol. 1). Vol. 1.

By: T. Jackson n, G. Bendfeldt n, K. Beam n, K. Rock n & S. Belcher n

co-author countries: United States of America 🇺🇸
Source: ORCID
Added: March 5, 2021

2020 journal article

Heterozygous mutation of sonic hedgehog receptor (Ptch1) drives cerebellar overgrowth and sex-specifically alters hippocampal and cortical layer structure, activity, and social behavior in female mice

NEUROTOXICOLOGY AND TERATOLOGY, 78.

By: T. Jackson n, G. Bendfeldt n, K. Beam n, K. Rock n & S. Belcher n

co-author countries: United States of America 🇺🇸

Contributors: T. Jackson n, G. Bendfeldt n, K. Beam n, K. Rock n & S. Belcher n

author keywords: Cerebellum; Cortex; Holoprosencephaly; Hyperactivity; Medial prefrontal cortex; Medulloblastoma; Sex differences
MeSH headings : Animals; Cerebellum / anatomy & histology; Cerebellum / physiology; Cerebral Cortex / anatomy & histology; Cerebral Cortex / physiology; Female; Heterozygote; Hippocampus / anatomy & histology; Hippocampus / physiology; Mice, Knockout; Mutation; Patched-1 Receptor / genetics; Patched-1 Receptor / physiology; Sex Characteristics; Signal Transduction; Social Behavior
Sources: Web Of Science, ORCID
Added: April 14, 2020

2019 journal article

Elevated metabolites of acetaminophen in cord blood of children with obesity

PEDIATRIC OBESITY, 14(1).

By: P. Sorrow n, R. Maguire n, S. Murphy*, S. Belcher n & C. Hoyo n

co-author countries: United States of America 🇺🇸

Contributors: P. Sorrow n, R. Maguire n, S. Murphy*, S. Belcher n & C. Hoyo n

author keywords: Acetaminophen; children; metabolomics; obesity
MeSH headings : Acetaminophen / blood; Acetaminophen / metabolism; Case-Control Studies; Child, Preschool; Fatty Acids / blood; Female; Fetal Blood / metabolism; Humans; Male; Metabolomics / methods; Pediatric Obesity / blood; Pregnancy
Sources: Web Of Science, ORCID
Added: January 7, 2019

2019 journal article

Endocrine Disruption and Reproductive Pathology

TOXICOLOGIC PATHOLOGY, 47(8), 1049–1071.

By: S. Belcher n, J. Cline*, J. Conley*, S. Groeters*, W. Jefferson*, M. Law n, E. Mackey*, A. Suen* ...

co-author countries: Germany 🇩🇪 United States of America 🇺🇸

Contributors: S. Belcher n, J. Cline*, J. Conley*, S. Groeters*, W. Jefferson*, M. Law n, E. Mackey*, A. Suen* ...

author keywords: endocrine disrupters; environmental toxicology; fish pathology; hormonal carcinogenesis; reproductive system; nonhuman primate; rodent pathology
MeSH headings : Animals; Congresses as Topic; Endocrine Disruptors / toxicity; Female; Fetal Development / drug effects; Heart / drug effects; Heart / embryology; Humans; Male; Pregnancy; Prenatal Exposure Delayed Effects / chemically induced; Prenatal Exposure Delayed Effects / metabolism; Prenatal Exposure Delayed Effects / pathology; Receptors, Androgen / genetics; Receptors, Androgen / metabolism; Receptors, Estrogen / genetics; Receptors, Estrogen / metabolism; Reproduction / drug effects; Species Specificity; Testis / drug effects; Testis / embryology; Testis / pathology; Uterus / drug effects; Uterus / embryology; Uterus / pathology
Sources: Web Of Science, ORCID
Added: December 30, 2019

2019 journal article

Maternal cadmium exposure in the mouse leads to increased heart weight at birth and programs susceptibility to hypertension in adulthood

SCIENTIFIC REPORTS, 9(1).

By: K. Hudson n, S. Belcher n & M. Cowley n

co-author countries: United States of America 🇺🇸

Contributors: K. Hudson n, S. Belcher n & M. Cowley n

MeSH headings : Animals; Animals, Newborn; Body Weight / drug effects; Cadmium / adverse effects; Disease Models, Animal; Female; Gene Expression Profiling / methods; Gene Expression Regulation / drug effects; Gene Regulatory Networks / drug effects; Heart / anatomy & histology; Heart / drug effects; Hypotension / chemically induced; Hypotension / genetics; Maternal Exposure / adverse effects; Metabolic Networks and Pathways / drug effects; Mice; Organ Size / drug effects; Pregnancy; Prenatal Exposure Delayed Effects / chemically induced; Prenatal Exposure Delayed Effects / genetics; Sequence Analysis, RNA
Sources: Web Of Science, ORCID
Added: October 7, 2019

2018 journal article

CLARITY-BPA academic laboratory studies identify consistent low-dose Bisphenol A effects on multiple organ systems

Basic & Clinical Pharmacology & Toxicology, 125(S3), 14–31.

By: G. Prins*, H. Patisaul n, S. Belcher n & L. Vandenberg*

co-author countries: United States of America 🇺🇸

Contributors: G. Prins*, H. Patisaul n, S. Belcher n & L. Vandenberg*

author keywords: Bisphenol A; CLARITY-BPA; endocrine disruptor; endocrine-disrupting chemical; oestrogen
MeSH headings : Animals; Benzhydryl Compounds / toxicity; Congresses as Topic; Disease Models, Animal; Ecotoxicology / methods; Ecotoxicology / standards; Endocrine Disruptors / toxicity; Environmental Exposure / adverse effects; Environmental Pollutants / toxicity; Female; Fetal Development / drug effects; Guidelines as Topic; Humans; National Institute of Environmental Health Sciences (U.S.) / standards; Phenols / toxicity; Pregnancy; Prenatal Exposure Delayed Effects / chemically induced; Prenatal Exposure Delayed Effects / prevention & control; Rats, Sprague-Dawley; Risk Assessment / methods; Risk Assessment / standards; Toxicity Tests / methods; Toxicity Tests / standards; United States; United States Food and Drug Administration / standards
Sources: ORCID, Crossref
Added: August 17, 2019

2018 article

CLARITY-BPA: Heart (Belcher)

Belcher, S. (2018, August). Chemical Effects in Biological Systems (CEBS).

By: S. Belcher*

Source: ORCID
Added: March 5, 2021

2018 journal article

Duality of estrogen receptor beta action in cancer progression

CURRENT OPINION IN PHARMACOLOGY, 41, 66–73.

By: T. Guillette n, T. Jackson n & S. Belcher n

co-author countries: United States of America 🇺🇸

Contributors: T. Guillette n, T. Jackson n & S. Belcher n

MeSH headings : Animals; Breast Neoplasms / metabolism; Breast Neoplasms / pathology; Cerebellar Neoplasms / metabolism; Cerebellar Neoplasms / pathology; Estrogen Receptor alpha / metabolism; Estrogen Receptor beta / metabolism; Female; Humans; Male; Medulloblastoma / metabolism; Medulloblastoma / pathology; Prostatic Neoplasms / metabolism; Prostatic Neoplasms / pathology
Sources: Web Of Science, ORCID
Added: October 16, 2018

2017 journal article

Effects of bisphenol A on incidence and severity of cardiac lesions in the NCTR-Sprague-Dawley rat: A CLARITY-BPA study

Toxicology Letters, 275, 123–135.

By: R. Gear*, J. Kendziorski* & S. Belcher n

co-author countries: United States of America 🇺🇸

Contributors: R. Gear*, J. Kendziorski* & S. Belcher n

MeSH headings : Age Factors; Animals; Benzhydryl Compounds / toxicity; Body Weight / drug effects; Cardiomyopathies / chemically induced; Cardiomyopathies / pathology; Cardiotoxicity; Environmental Pollutants / toxicity; Female; Fibrosis; Male; Myocardium / pathology; Organ Size / drug effects; Phenols / toxicity; Rats, Sprague-Dawley; Severity of Illness Index; Sex Factors
Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2017 book

Endocrine Disruptors, Brain, and Behavior

In Oxford Scholarship Online.

By: H. Patisaul & S. Belcher*

Source: ORCID
Added: March 5, 2021

2017 journal article

Estrogen and soy isoflavonoids decrease sensitivity of medulloblastoma and central nervous system primitive neuroectodermal tumor cells to chemotherapeutic cytotoxicity

BMC PHARMACOLOGY & TOXICOLOGY, 18(1).

By: S. Belcher n, C. Burton*, C. Cookman*, M. Kirby*, G. Miranda*, F. Saeed*, K. Wray*

co-author countries: United States of America 🇺🇸

Contributors: S. Belcher n, C. Burton*, C. Cookman*, M. Kirby*, G. Miranda*, F. Saeed*, K. Wray*

author keywords: Chemotherapy; Cytoprotection; Concentration-response; Estrogen; In vitro; Isoflavones; Medulloblastoma; Phytoestrogen
Sources: Web Of Science, ORCID
Added: August 6, 2018

2017 journal article

Gestational high-fat diet and bisphenol A exposure heightens mammary cancer risk

Endocrine-Related Cancer, 24(7), 365–378.

By: Y. Leung, V. Govindarajah, A. Cheong, J. Veevers, D. Song, R. Gear*, X. Zhu, J. Ying ...

co-author countries: United States of America 🇺🇸

Contributors: Y. Leung, V. Govindarajah, A. Cheong, J. Veevers, D. Song, R. Gear*, X. Zhu, J. Ying ...

author keywords: breast cancer; developmental origin of health and disease (DOHaD); RNA-seq; transcriptomics; DNA methylation; patient survival; TCGA; windows of susceptibility; in utero exposure; bisphenol A; high-butter fat diet; non-monotonic response
MeSH headings : Animals; Benzhydryl Compounds / administration & dosage; Benzhydryl Compounds / toxicity; Diet, High-Fat; Female; Mammary Glands, Animal / drug effects; Mammary Neoplasms, Experimental / chemically induced; Mammary Neoplasms, Experimental / etiology; Mammary Neoplasms, Experimental / pathology; Phenols / administration & dosage; Phenols / toxicity; Random Allocation; Rats; Risk
Source: ORCID
Added: March 5, 2021

2017 journal article

Impacts of Bisphenol A and Ethinyl Estradiol on Male and Female CD-1 Mouse Spleen

SCIENTIFIC REPORTS, 7(1).

By: R. Gear* & S. Belcher n

co-author countries: United States of America 🇺🇸

Contributors: R. Gear* & S. Belcher n

MeSH headings : Animals; Benzhydryl Compounds / toxicity; Endocrine Disruptors / toxicity; Estrogens / toxicity; Ethinyl Estradiol / toxicity; Female; Male; Mice; Phenols / toxicity; Sex Factors; Spleen / drug effects; Spleen / ultrastructure
Sources: Web Of Science, ORCID
Added: August 6, 2018

2016 journal article

Impact of Low Dose Oral Exposure to Bisphenol A (BPA) on the Neonatal Rat Hypothalamic and Hippocampal Transcriptome: A CLARITY-BPA Consortium Study

Endocrinology, 157(10), 3856–3872.

By: S. Arambula n, S. Belcher n, A. Planchart n, S. Turner* & H. Patisaul n

co-author countries: United States of America 🇺🇸

Contributors: S. Arambula n, S. Belcher n, A. Planchart n, S. Turner* & H. Patisaul n

MeSH headings : Administration, Oral; Animals; Animals, Newborn; Benzhydryl Compounds / administration & dosage; Benzhydryl Compounds / toxicity; Estrogens, Non-Steroidal / administration & dosage; Estrogens, Non-Steroidal / toxicity; Female; Gene Expression / drug effects; Hippocampus / drug effects; Hippocampus / metabolism; Hypothalamus / drug effects; Hypothalamus / metabolism; Male; Phenols / administration & dosage; Phenols / toxicity; Random Allocation; Rats; Rats, Sprague-Dawley; Sex Characteristics; Transcriptome / drug effects
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018

2015 journal article

Bisphenol a alters autonomic tone and extracellular matrix structure and induces sex-specific effects on cardiovascular function in male and female CD-1 mice

Endocrinology, 156(3), 882–895.

By: S. Belcher*, R. Gear* & E. Kendig*

co-author countries: United States of America 🇺🇸

Contributors: S. Belcher*, R. Gear* & E. Kendig*

MeSH headings : Animals; Baroreflex / drug effects; Benzhydryl Compounds / administration & dosage; Benzhydryl Compounds / pharmacology; Blood Pressure / drug effects; Cardiomegaly / chemically induced; Dose-Response Relationship, Drug; Electrocardiography; Estrogens, Non-Steroidal / administration & dosage; Estrogens, Non-Steroidal / pharmacology; Ethinyl Estradiol / pharmacology; Extracellular Matrix; Female; Male; Mice; Mice, Inbred Strains; Myocardium / pathology; Phenols / administration & dosage; Phenols / pharmacology; Receptors, Adrenergic, beta; Sex Factors; Sympathetic Nervous System / drug effects
Source: ORCID
Added: March 5, 2021

2015 journal article

Effects of whole life exposure to Bisphenol A or 17α-ethinyl estradiol in uterus of nulligravida CD1 mice

Data in Brief, 5, 948–953.

By: J. Kendziorski* & S. Belcher*

co-author countries: United States of America 🇺🇸

Contributors: J. Kendziorski* & S. Belcher*

author keywords: BPA; Estrogen; EDC; endocrine disruption; Collagen; Fibrosis; Immune; Macrophage
Sources: Crossref, ORCID
Added: August 28, 2020

2015 journal article

Estrogen receptor-β up-regulates IGF1R expression and activity to inhibit apoptosis and increase growth of medulloblastoma

Endocrinology, 156(7), 2395–2408.

By: C. Cookman* & S. Belcher*

co-author countries: United States of America 🇺🇸

Contributors: C. Cookman* & S. Belcher*

MeSH headings : Animals; Apoptosis / drug effects; Apoptosis / genetics; Caspase 3 / metabolism; Cell Line, Tumor; Estradiol / pharmacology; Estrogen Receptor beta / genetics; Estrogen Receptor beta / metabolism; Female; Gene Expression Regulation, Neoplastic / drug effects; Gene Expression Regulation, Neoplastic / genetics; Humans; Insulin-Like Growth Factor I / drug effects; Insulin-Like Growth Factor I / genetics; Insulin-Like Growth Factor I / metabolism; Insulin-Like Growth Factor II / drug effects; Insulin-Like Growth Factor II / genetics; Insulin-Like Growth Factor II / metabolism; Male; Medulloblastoma / genetics; Medulloblastoma / metabolism; Mice; Mice, Knockout; Patched Receptors; Patched-1 Receptor; Proto-Oncogene Proteins c-bcl-2 / drug effects; Proto-Oncogene Proteins c-bcl-2 / metabolism; RNA, Messenger / drug effects; RNA, Messenger / metabolism; Receptor, IGF Type 1 / drug effects; Receptor, IGF Type 1 / genetics; Receptor, IGF Type 1 / metabolism; Receptors, Cell Surface / genetics; Reverse Transcriptase Polymerase Chain Reaction; Tumor Suppressor Protein p53 / genetics; Up-Regulation / drug effects; Up-Regulation / genetics
Source: ORCID
Added: March 5, 2021

2015 journal article

New Master of Science program emphasizing Safety Pharmacology—Results to date

Journal of Pharmacological and Toxicological Methods, 75, 191–192.

By: A. Matlib*, S. Belcher*, R. Rapoport*, R. Millard*, H. Wang* & J. Maggio*

co-author countries: United States of America 🇺🇸
Sources: Crossref, ORCID
Added: August 28, 2020

2015 journal article

Non-monotonic dose-response relationships and endocrine disruptors: A qualitative method of assessment -No section-

Environmental Health: A Global Access Science Source, 14(1).

By: F. Lagarde*, C. Beausoleil*, S. Belcher*, L. Belzunces, C. Emond*, M. Guerbet*, C. Rousselle*

co-author countries: France 🇫🇷 United States of America 🇺🇸

Contributors: F. Lagarde*, C. Beausoleil*, S. Belcher*, L. Belzunces, C. Emond*, M. Guerbet*, C. Rousselle*

author keywords: Endocrine disruptors; NMDR; Non-monotonic; Dose-response; Risk assessment; Bisphenol A
MeSH headings : Dose-Response Relationship, Drug; Endocrine Disruptors / toxicity; Environmental Exposure; Environmental Monitoring / methods; Environmental Pollutants / toxicity; Risk Assessment
Source: ORCID
Added: March 5, 2021

2015 journal article

Response to the letter by Gallo D., et al

Endocrinology, 156(8), L8–L9.

By: S. Belcher*

Contributors: S. Belcher*

MeSH headings : Animals; Apoptosis / genetics; Estrogen Receptor beta / genetics; Female; Gene Expression Regulation, Neoplastic / genetics; Humans; Male; Medulloblastoma / genetics; RNA, Messenger / metabolism; Receptor, IGF Type 1 / genetics
Source: ORCID
Added: March 5, 2021

2015 journal article

Strain-specific induction of endometrial periglandular fibrosis in mice exposed during adulthood to the endocrine disrupting chemical bisphenol A

Reproductive Toxicology, 58, 119–130.

By: J. Kendziorski* & S. Belcher*

co-author countries: United States of America 🇺🇸

Contributors: J. Kendziorski* & S. Belcher*

author keywords: BPA; Endocrine disruptor; Uterus; Mouse; Collagen; Dose response; Endometrial periglandular fibrosis; Equine endometrosis; Matrix metalloproteinase; Non-monotonic
MeSH headings : Age Factors; Animals; Benzhydryl Compounds / toxicity; Collagen Type I / metabolism; Collagen Type III / metabolism; Endocrine Disruptors / toxicity; Endometriosis / chemically induced; Endometriosis / genetics; Endometriosis / metabolism; Endometriosis / pathology; Endometrium / drug effects; Endometrium / metabolism; Endometrium / pathology; Female; Fibrosis; Matrix Metalloproteinase 14 / genetics; Matrix Metalloproteinase 14 / metabolism; Matrix Metalloproteinase 2 / genetics; Matrix Metalloproteinase 2 / metabolism; Mice, Inbred C57BL; Phenols / toxicity; Phenotype; Species Specificity
Sources: Crossref, ORCID
Added: February 24, 2020

2014 journal article

Actions of endocrine-disrupting chemicals on stem/progenitor cells during development and disease

Endocrine-Related Cancer, 21(2).

By: E. Kopras*, V. Potluri*, M. Bermudez*, K. Williams*, S. Belcher* & S. Kasper*

co-author countries: United States of America 🇺🇸

Contributors: E. Kopras*, V. Potluri*, M. Bermudez*, K. Williams*, S. Belcher* & S. Kasper*

author keywords: endocrine disruptors; stem cell/progenitor cell; cancer stem cell; organ development; steroid hormone receptors
MeSH headings : Adipogenesis / drug effects; Animals; Bone Development / drug effects; Disease; Endocrine Disruptors / toxicity; Environmental Pollutants / toxicity; Germ Cells / drug effects; Heart / drug effects; Humans; Immune System / drug effects; Male; Mammary Glands, Human / drug effects; Neurogenesis / drug effects; Prostate / drug effects; Stem Cells / drug effects
Source: ORCID
Added: March 5, 2021

2014 journal article

Bisphenol A and cardiometabolic risk factors in obese children

Science of The Total Environment, 470-471, 726–732.

By: N. Khalil*, J. Ebert*, L. Wang*, S. Belcher*, M. Lee*, S. Czerwinski*, K. Kannan*

co-author countries: United States of America 🇺🇸

Contributors: N. Khalil*, J. Ebert*, L. Wang*, S. Belcher*, M. Lee*, S. Czerwinski*, K. Kannan*

author keywords: Bisphenol A; Endocrine disruptor; Non-monotonic dose response; Childhood obesity; Nonalcoholic fatty liver disease; Spline analysis
MeSH headings : Anthropometry; Aspartate Aminotransferases / blood; Benzhydryl Compounds / blood; Body Mass Index; Child; Endocrine Disruptors / blood; Fatty Liver / blood; Fatty Liver / epidemiology; Female; Humans; Insulin Resistance; Male; Non-alcoholic Fatty Liver Disease; Obesity / blood; Obesity / epidemiology; Ohio / epidemiology; Phenols / blood; Risk Factors
Sources: Crossref, ORCID
Added: August 28, 2020

2014 journal article

Classical nuclear hormone receptor activity as a mediator of complex concentration response relationships for endocrine active compounds

Current Opinion in Pharmacology, 19, 112–119.

By: C. Cookman & S. Belcher*

Contributors: C. Cookman & S. Belcher*

MeSH headings : Animals; Cell Survival / drug effects; Dose-Response Relationship, Drug; Endocrine Disruptors / toxicity; Humans; Receptors, Cytoplasmic and Nuclear / metabolism
Sources: Crossref, ORCID
Added: August 28, 2020

2014 journal article

Editorial overview: Endocrine and metabolic diseases: Conversations on endocrine disruptors — rising above the din

Current Opinion in Pharmacology, 19, vi-vii.

By: S. Belcher*

co-author countries: United States of America 🇺🇸

Contributors: S. Belcher*

MeSH headings : Endocrine Disruptors / toxicity; Endocrine System Diseases; Environmental Exposure / adverse effects; Environmental Pollutants / toxicity; Humans; Metabolic Diseases; Risk Assessment
Sources: Crossref, ORCID
Added: December 21, 2020

2014 journal article

In vitro assessment of human nuclear hormone receptor activity and cytotoxicity of the flame retardant mixture FM 550 and its triarylphosphate and brominated components

Toxicology Letters, 228(2), 93–102.

By: S. Belcher*, C. Cookman*, H. Patisaul n & H. Stapleton*

co-author countries: United States of America 🇺🇸

Contributors: S. Belcher*, C. Cookman*, H. Patisaul n & H. Stapleton*

author keywords: Apoptosis Endocrine disruptor; Flame retardant; Nuclear receptors; Obesity; Peroxisome proliferator-activated receptor
MeSH headings : Adipocytes / drug effects; Animals; CHO Cells; Caspase 3 / metabolism; Cell Survival / drug effects; Cricetinae; Cricetulus; Endocrine Disruptors / toxicity; Flame Retardants / toxicity; Humans; Ligands; Organophosphates / chemistry; Organophosphates / toxicity; Organotin Compounds / toxicity; PPAR gamma / drug effects; PPAR gamma / metabolism; Receptors, Cytoplasmic and Nuclear / drug effects; Transcriptional Activation / drug effects
Sources: Crossref, ORCID, Web Of Science
Added: August 6, 2018

2013 journal article

Accumulation and Endocrine Disrupting Effects of the Flame Retardant Mixture Firemaster® 550 in Rats: An Exploratory Assessment

Journal of Biochemical and Molecular Toxicology, 27(2), 124–136.

By: H. Patisaul n, S. Roberts*, N. Mabrey n, K. McCaffrey n, R. Gear*, J. Braun*, S. Belcher*, H. Stapleton*

co-author countries: United States of America 🇺🇸

Contributors: H. Patisaul n, S. Roberts*, N. Mabrey n, K. Mccaffrey n, R. Gear*, J. Braun*, S. Belcher*, H. Stapleton*

author keywords: Anxiety; Cardiac Hypertrophy; Endocrine Disruptor; Flame Retardants; Metabolic Syndrome; Metabolism; Obesity; Obesogen; Polybrominated Diphenyl Ethers; Rodents
MeSH headings : Animals; Cardiomegaly / blood; Cardiomegaly / chemically induced; Cardiomegaly / pathology; Endocrine System / metabolism; Endocrine System / pathology; Endocrine System / physiology; Female; Flame Retardants / adverse effects; Male; Maternal Exposure / adverse effects; Obesity / blood; Obesity / chemically induced; Obesity / pathology; Pregnancy; Prenatal Exposure Delayed Effects / blood; Prenatal Exposure Delayed Effects / pathology; Rats; Rats, Wistar; Thyroxine / blood
Sources: Crossref, ORCID, Web Of Science
Added: August 6, 2018

2013 journal article

The estrogenic content of rodent diets, bedding, cages, and water bottles and its effect on bisphenol a studies

Journal of the American Association for Laboratory Animal Science, 52(2), 130–141. http://www.scopus.com/inward/record.url?eid=2-s2.0-84875526300&partnerID=MN8TOARS

By: J. Thigpen, K. Setchell, G. Kissling, J. Locklear, G. Caviness, T. Whiteside, S. Belcher, N. Brown ...

Contributors: J. Thigpen, K. Setchell, G. Kissling, J. Locklear, G. Caviness, T. Whiteside, S. Belcher, N. Brown ...

Source: ORCID
Added: March 5, 2021

2012 journal article

Estrogen-like disruptive effects of dietary exposure to bisphenol A or 17α-ethinyl estradiol in CD1 mice

International Journal of Toxicology, 31(6), 537–550.

By: E. Kendig*, D. Buesing*, S. Christie*, C. Cookman*, R. Gear*, E. Hugo*, S. Kasper*, J. Kendziorski* ...

co-author countries: United States of America 🇺🇸

Contributors: E. Kendig*, D. Buesing*, S. Christie*, C. Cookman*, R. Gear*, E. Hugo*, S. Kasper*, J. Kendziorski* ...

author keywords: Bisphenol A; diabetes; endocrine disruptor; estrogen; metabolic effects; obesity; prolactin
MeSH headings : Animal Feed; Animals; Benzhydryl Compounds / toxicity; Dose-Response Relationship, Drug; Endocrine Disruptors / toxicity; Environmental Pollutants / toxicity; Estrogens / toxicity; Ethinyl Estradiol / toxicity; Female; Glucose Tolerance Test; Male; Maternal Exposure; Mice; Mice, Inbred Strains; No-Observed-Adverse-Effect Level; Obesity / chemically induced; Organ Size / drug effects; Paternal Exposure; Phenols / toxicity; Reproduction / drug effects; Sex Factors; Sexual Maturation / drug effects; Sperm Count; Spermatozoa / drug effects; Uterus / drug effects
Source: ORCID
Added: March 5, 2021

2012 journal article

Inhibition of stathmin1 accelerates the metastatic process

Cancer Research, 72(20), 5407–5417.

By: K. Williams*, R. Ghosh*, P. Giridhar*, G. Gu*, T. Case*, S. Belcher*, S. Kasper*

co-author countries: United States of America 🇺🇸

Contributors: K. Williams*, R. Ghosh*, P. Giridhar*, G. Gu*, T. Case*, S. Belcher*, S. Kasper*

MeSH headings : Base Sequence; Cells, Cultured; DNA Primers; Down-Regulation; Humans; Male; Neoplasm Metastasis; Signal Transduction; Stathmin / antagonists & inhibitors
Source: ORCID
Added: March 5, 2021

2012 journal article

Rapid estrogen receptor-mediated mechanisms determine the sexually dimorphic sensitivity of ventricular myocytes to 17β-estradiol and the environmental endocrine disruptor bispheno A

Endocrinology, 153(2), 712–720.

By: S. Belcher*, Y. Chen*, S. Yan* & H. Wang*

co-author countries: United States of America 🇺🇸

Contributors: S. Belcher*, Y. Chen*, S. Yan* & H. Wang*

MeSH headings : Animals; Benzhydryl Compounds; Calcium / metabolism; Calcium Signaling / physiology; Cells, Cultured; Dose-Response Relationship, Drug; Endocrine Disruptors / pharmacology; Estradiol / administration & dosage; Estradiol / pharmacology; Female; Male; Mice; Mice, Knockout; Myocardial Contraction / drug effects; Myocytes, Cardiac / drug effects; Myocytes, Cardiac / physiology; Phenols / administration & dosage; Phenols / pharmacology; Rats; Rats, Sprague-Dawley; Receptors, Estrogen / genetics; Receptors, Estrogen / metabolism; Sex Characteristics
Source: ORCID
Added: March 5, 2021

2012 journal article

Strain specific induction of pyometra and differences in immune responsiveness in mice exposed to 17α-ethinyl estradiol or the endocrine disrupting chemical bisphenol A

Reproductive Toxicology, 34(1), 22–30.

By: J. Kendziorski*, E. Kendig*, R. Gear* & S. Belcher*

co-author countries: United States of America 🇺🇸

Contributors: J. Kendziorski*, E. Kendig*, R. Gear* & S. Belcher*

author keywords: Bisphenol A; Macrophage; Pyometra; Uterus; Mouse; Estrogen; Endocrine disruptor; Immune response
MeSH headings : Animals; Benzhydryl Compounds; Cell Count; Endocrine Disruptors / toxicity; Estrogens, Non-Steroidal / toxicity; Ethinyl Estradiol / toxicity; Female; Fertility / drug effects; Macrophages / cytology; Macrophages / drug effects; Macrophages / immunology; Male; Mice; Mice, Inbred C57BL; Phenols / toxicity; Pyometra / chemically induced; Pyometra / immunology; Pyometra / pathology; Species Specificity; Uterus / drug effects; Uterus / immunology; Uterus / pathology
Sources: Crossref, ORCID
Added: August 28, 2020

2011 journal article

Assessment of bisphenol A released from reusable plastic, aluminium and stainless steel water bottles

Chemosphere, 85(6), 943–947.

By: J. Cooper*, E. Kendig* & S. Belcher*

co-author countries: United States of America 🇺🇸

Contributors: J. Cooper*, E. Kendig* & S. Belcher*

author keywords: Bisphenol A; Copolyester; Epoxy resins; Endocrine disrupting chemicals; Polycarbonate; Water bottles
MeSH headings : Aluminum / chemistry; Benzhydryl Compounds; Endocrine Disruptors / analysis; Endocrine Disruptors / chemistry; Food Packaging / methods; Phenols / analysis; Phenols / chemistry; Plastics / chemistry; Recycling; Stainless Steel / chemistry; Water / chemistry
Sources: Crossref, ORCID
Added: August 28, 2020

2011 journal article

Bisphenol A and 17β-estradiol promote arrhythmia in the female heart via alteration of calcium handling

PLoS ONE, 6(9).

co-author countries: United States of America 🇺🇸

Contributors: S. Yan*, Y. Chen*, M. Dong*, W. Song*, S. Belcher* & H. Wang*

MeSH headings : Animals; Arrhythmias, Cardiac / chemically induced; Arrhythmias, Cardiac / metabolism; Arrhythmias, Cardiac / pathology; Benzhydryl Compounds; Calcium Signaling / drug effects; Dose-Response Relationship, Drug; Endocrine Disruptors / pharmacology; Estradiol / pharmacology; Estrogen Receptor beta / deficiency; Estrogen Receptor beta / genetics; Estrogens / pharmacology; Female; Gene Knockout Techniques; Heart / drug effects; Heart Ventricles / drug effects; Heart Ventricles / pathology; Male; Mice; Myocytes, Cardiac / drug effects; Myocytes, Cardiac / pathology; Phenols / pharmacology; Rats; Sarcoplasmic Reticulum / drug effects; Sarcoplasmic Reticulum / metabolism; Sex Characteristics; Time Factors
Source: ORCID
Added: March 5, 2021

2010 journal article

Defining hormesis: Evaluation of a complex concentration response phenomenon

International Journal of Toxicology, 29(3), 235–246.

By: E. Kendig*, H. Le* & S. Belcher*

co-author countries: United States of America 🇺🇸

Contributors: E. Kendig*, H. Le* & S. Belcher*

author keywords: hormesis; dose-response relationship; threshold model; beta-curve; biphasic effects; nonmonotonic; low-dose effects; subthreshold response
MeSH headings : Animals; Dose-Response Relationship, Drug; History, 16th Century; History, 19th Century; History, Ancient; Humans; Models, Biological; Nonlinear Dynamics; Pharmacokinetics; Pharmacology / methods; Terminology as Topic; Toxicology / history; Toxicology / methods
Source: ORCID
Added: March 5, 2021

2010 journal article

Flawed experimental design reveals the need for guidelines requiring appropriate positive controls in endocrine disruption research

Toxicological Sciences, 115(2), 612–613.

By: F. Saal*, B. Akingbemi*, S. Belcher*, D. Crain*, D. Crews*, L. Guidice*, P. Hunt*, C. Leranth* ...

co-author countries: Germany 🇩🇪 Spain 🇪🇸 United States of America 🇺🇸

Contributors: F. Saal*, B. Akingbemi*, S. Belcher*, D. Crain*, D. Crews*, L. Guidice*, P. Hunt*, C. Leranth* ...

MeSH headings : Animals; Dose-Response Relationship, Drug; Endocrine Disruptors / toxicity; Estrogens, Non-Steroidal / toxicity; Ethinyl Estradiol / toxicity; Female; Fertility / drug effects; Genitalia, Female / abnormalities; Genitalia, Female / drug effects; Guidelines as Topic; Male; Maternal Exposure; No-Observed-Adverse-Effect Level; Pregnancy; Rats; Rats, Long-Evans; Research Design / standards; Toxicity Tests / methods; Toxicity Tests / standards
Source: ORCID
Added: March 5, 2021

2010 journal article

Rapid signaling actions of environmental estrogens in developing granule cell neurons are mediated by estrogen receptor β

Endocrinology, 151(12), 5689–5699.

By: H. Le* & S. Belcher*

co-author countries: United States of America 🇺🇸

Contributors: H. Le* & S. Belcher*

MeSH headings : Animals; Cell Death; Endocrine Disruptors / chemistry; Endocrine Disruptors / pharmacology; Environmental Pollutants; Estrogen Receptor beta / metabolism; Estrogens / chemistry; Estrogens / pharmacology; Extracellular Signal-Regulated MAP Kinases / metabolism; Female; Molecular Structure; Neurons / cytology; Neurons / drug effects; Neurons / physiology; Phosphorylation; Rats; Rats, Sprague-Dawley; Signal Transduction
Source: ORCID
Added: March 5, 2021

2009 journal article

Blockade of estrogen receptor signaling inhibits growth and migration of medulloblastoma

Endocrinology, 150(3), 1112–1121.

By: S. Belcher*, X. Ma* & H. Le*

co-author countries: United States of America 🇺🇸

Contributors: S. Belcher*, X. Ma* & H. Le*

MeSH headings : Adolescent; Animals; Cell Movement / drug effects; Cell Proliferation / drug effects; Cells, Cultured; Cerebellar Neoplasms / genetics; Cerebellar Neoplasms / metabolism; Cerebellar Neoplasms / pathology; Child; Child, Preschool; Down-Regulation / drug effects; Estradiol / analogs & derivatives; Estradiol / pharmacology; Estrogen Antagonists / pharmacology; Female; Fulvestrant; Humans; Infant; Male; Medulloblastoma / genetics; Medulloblastoma / metabolism; Medulloblastoma / pathology; Mice; Mice, Nude; Rats; Rats, Sprague-Dawley; Receptors, Estrogen / antagonists & inhibitors; Receptors, Estrogen / genetics; Receptors, Estrogen / metabolism; Signal Transduction / drug effects; Signal Transduction / physiology; Xenograft Model Antitumor Assays
Source: ORCID
Added: March 5, 2021

2009 journal article

Blockade of estrogen receptor signaling to improve outlook for medulloblastoma sufferers

Future Oncology, 5(6), 751–754.

By: S. Belcher*

co-author countries: United States of America 🇺🇸

Contributors: S. Belcher*

MeSH headings : Adolescent; Antineoplastic Agents / pharmacology; Antineoplastic Agents / therapeutic use; Antineoplastic Combined Chemotherapy Protocols; Cerebellar Neoplasms / drug therapy; Child; Child, Preschool; Drug Synergism; Estrogen Antagonists / therapeutic use; Humans; Infant; Medulloblastoma / drug therapy; Receptors, Estrogen / antagonists & inhibitors; Signal Transduction / drug effects; Young Adult
Source: ORCID
Added: March 5, 2021

2009 journal article

Good laboratory practices: Myers et al. respond

Environmental Health Perspectives, 117(11).

By: J. Myers, F. Vom Saal*, J. Taylor*, B. Akingbemi*, K. Arizono*, S. Belcher*, T. Colborn*, I. Chahoud*

co-author countries: Germany 🇩🇪 Japan 🇯🇵 United States of America 🇺🇸

Contributors: J. Myers, F. Vom Saal*, J. Taylor*, B. Akingbemi*, K. Arizono*, S. Belcher*, T. Colborn*, I. Chahoud*

Source: ORCID
Added: March 5, 2021

2009 journal article

Why public health agencies cannot depend on good laboratory practices as a criterion for selecting data: The case of bisphenol A

Environmental Health Perspectives, 117(3), 309–315.

Contributors: J. Myers, F. Saal*, B. Akingbemi*, K. Arizono*, S. Belcher*, T. Colborn*, I. Chahoud*, D. Crain* ...

author keywords: bisphenol A; endocrine disruptors; FDA; Food and Drug Administration; GLP; good laboratory practices; low-dose; nonmonotonic; positive control
MeSH headings : Benzhydryl Compounds; Clinical Laboratory Techniques / standards; Ecotoxicology / methods; Ecotoxicology / standards; Endocrine Disruptors / toxicity; Phenols / toxicity; Public Health Practice / standards; Risk Assessment / methods; Risk Assessment / standards
Source: ORCID
Added: March 5, 2021

2008 journal article

Bisphenol A is released from polycarbonate drinking bottles and mimics the neurotoxic actions of estrogen in developing cerebellar neurons

Toxicology Letters, 176(2), 149–156.

By: H. Le*, E. Carlson*, J. Chua* & S. Belcher*

co-author countries: United States of America 🇺🇸

Contributors: H. Le*, E. Carlson*, J. Chua* & S. Belcher*

author keywords: BPA endocrine disruption; estrogen; neurotoxicity; non-genomic
MeSH headings : Animals; Animals, Newborn; Benzhydryl Compounds; Cell Survival / drug effects; Cells, Cultured; Cerebellum / cytology; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Endocrine Disruptors / chemistry; Endocrine Disruptors / metabolism; Endocrine Disruptors / toxicity; Enzyme-Linked Immunosorbent Assay; Estradiol / pharmacology; Estrogens / toxicity; Female; Humans; Immunochemistry; L-Lactate Dehydrogenase / metabolism; Neurons / cytology; Neurons / drug effects; Neurons / metabolism; Phenols / chemistry; Phenols / metabolism; Phenols / toxicity; Polycarboxylate Cement / chemistry; Product Packaging; Rats; Rats, Sprague-Dawley; Temperature; Time Factors; Water / analysis; Water / chemistry
Sources: Crossref, ORCID
Added: August 28, 2020

2008 book

Cardiovascular effects of steroidal agents

In Cardiovascular Toxicology, Fourth Edition (pp. 367–428). http://www.scopus.com/inward/record.url?eid=2-s2.0-85057367081&partnerID=MN8TOARS

By: R. Melchert, S. Belcher & R. Kennedy

Contributors: R. Melchert, S. Belcher & R. Kennedy

Source: ORCID
Added: March 5, 2021

2008 journal article

Rapid signaling mechanisms of estrogens in the developing cerebellum

Brain Research Reviews, 57(2), 481–492.

By: S. Belcher*

co-author countries: United States of America 🇺🇸

Contributors: S. Belcher*

author keywords: cerebellum; development; ERK; estrogen; non-genomic; signal transduction
MeSH headings : Animals; Brain Neoplasms / metabolism; Cerebellum / embryology; Cerebellum / metabolism; Child; Estrogens / metabolism; Humans; Receptors, Estrogen / metabolism; Signal Transduction / physiology
Sources: Crossref, ORCID
Added: January 21, 2021

2007 journal article

Chapel Hill bisphenol A expert panel consensus statement: Integration of mechanisms, effects in animals and potential to impact human health at current levels of exposure

Reproductive Toxicology, 24(2), 131–138.

By: F. vom Saal*, B. Akingbemi*, S. Belcher*, L. Birnbaum*, D. Crain*, M. Eriksen, F. Farabollini*, L. Guillette* ...

co-author countries: United Kingdom of Great Britain and Northern Ireland 🇬🇧 Italy 🇮🇹 Japan 🇯🇵 United States of America 🇺🇸

Contributors: F. Saal*, B. Akingbemi*, S. Belcher*, L. Birnbaum*, D. Crain*, M. Eriksen, F. Farabollini*, L. Guillette Jr. ...

author keywords: bisphenol A; in vitro; in vivo; rat; mouse; aquatic animal; cancer; low dose; non-monotonic dose-response curves; developmental programming
MeSH headings : Air Pollutants, Occupational / poisoning; Animals; Animals, Wild; Benzhydryl Compounds; Consensus; Dose-Response Relationship, Drug; Estrogens, Non-Steroidal / poisoning; Female; Humans; Male; Models, Animal; National Institutes of Health (U.S.); North Carolina; Phenols / poisoning; Pregnancy; Prenatal Exposure Delayed Effects; Risk Assessment / methods; Risk Assessment / standards; United States; United States Environmental Protection Agency
Sources: Crossref, ORCID
Added: March 8, 2020

2007 journal article

In vitro molecular mechanisms of bisphenol A action

Reproductive Toxicology, 24(2), 178–198.

By: Y. Wetherill*, B. Akingbemi*, J. Kanno*, J. McLachlan*, A. Nadal*, C. Sonnenschein*, C. Watson*, R. Zoeller*, S. Belcher*

co-author countries: Spain 🇪🇸 Japan 🇯🇵 United States of America 🇺🇸

Contributors: Y. Wetherill*, B. Akingbemi*, J. Kanno*, J. McLachlan*, A. Nadal*, C. Sonnenschein*, C. Watson*, R. Zoeller*, S. Belcher*

author keywords: bisphenol A (BPA, 2,2-bis(4-hydroxyphenyl) propane; endocrine disruption; endocrine disrupting chemical (EDC); rapid signaling; estrogen receptor; androgen receptor; thyroid receptor; thyroid hormone; GPR30; non-classical membrane estrogen receptor; immune system; allergic resonse; in vitro mechanisms; cell specificity; expert panel review
MeSH headings : Animals; Benzhydryl Compounds; Dose-Response Relationship, Drug; Endocrine Disruptors / pharmacokinetics; Endocrine Disruptors / toxicity; Environmental Exposure / analysis; Female; Fertility / drug effects; Humans; Male; Phenols / chemistry; Phenols / pharmacokinetics; Phenols / toxicity; Reproduction / drug effects
Sources: Crossref, ORCID
Added: August 28, 2020

2006 journal article

Immunolocalization of ecto-nucleoside triphosphate diphosphohydrolase 3 in rat brain: Implications for modulation of multiple homeostatic systems including feeding and sleep–wake behaviors

Neuroscience, 137(4), 1331–1346.

By: S. Belcher*, A. Zsarnovszky*, P. Crawford*, H. Hemani*, L. Spurling* & T. Kirley*

co-author countries: United States of America 🇺🇸

Contributors: S. Belcher*, A. Zsarnovszky*, P. Crawford*, H. Hemani*, L. Spurling* & T. Kirley*

author keywords: nucleoside triphosphate diphosphohydrolase; NTPDase3; CD39L3; immunohistochemistry; purinergic signaling; orexin/hypocretin co-localization
MeSH headings : Adenosine Triphosphate / metabolism; Amino Acid Sequence; Animals; Brain / enzymology; Brain / physiology; Cloning, Molecular; Feeding Behavior / physiology; Female; Homeostasis; Molecular Sequence Data; Nerve Fibers / enzymology; Ovariectomy; Peptide Fragments / chemistry; Peptide-N4-(N-acetyl-beta-glucosaminyl) Asparagine Amidase / metabolism; Pyrophosphatases / genetics; Pyrophosphatases / metabolism; Rats; Sleep / physiology; Wakefulness / physiology
Sources: Crossref, ORCID
Added: January 21, 2021

2005 journal article

Ontogeny of rapid estrogen-mediated extracellular signal-regulated kinase signaling in the rat cerebellar cortex: Potent nongenomic agonist and endocrine disrupting activity of the xenoestrogen bisphenol A

Endocrinology, 146(12), 5388–5396.

By: A. Zsarnovszky*, H. Le*, H. Wang* & S. Belcher*

co-author countries: United States of America 🇺🇸

Contributors: A. Zsarnovszky*, H. Le*, H. Wang* & S. Belcher*

MeSH headings : Aging / metabolism; Animals; Animals, Newborn; Benzhydryl Compounds; Cerebellar Cortex / enzymology; Dose-Response Relationship, Drug; Drug Combinations; Endocrine System / drug effects; Estradiol / administration & dosage; Estradiol / pharmacology; Estrogens, Non-Steroidal / administration & dosage; Estrogens, Non-Steroidal / pharmacology; Extracellular Signal-Regulated MAP Kinases / metabolism; Female; Immunohistochemistry; Male; Phenols / administration & dosage; Phenols / pharmacology; Rats; Rats, Sprague-Dawley; Signal Transduction / drug effects
Source: ORCID
Added: March 5, 2021

2005 journal article

Rapid estrogenic regulation of extracellular signal-regulated kinase 1/2 signaling in cerebellar granule cells involves a G protein- and protein kinase A-dependent mechanism and intracellular activation of protein phosphatase 2A

Endocrinology, 146(12), 5397–5406.

By: S. Belcher*, H. Le*, L. Spurling* & J. Wong*

co-author countries: United States of America 🇺🇸

Contributors: S. Belcher*, H. Le*, L. Spurling* & J. Wong*

MeSH headings : Animals; Cells, Cultured; Cerebellum / cytology; Cerebellum / metabolism; Cyclic AMP-Dependent Protein Kinases / physiology; Enzyme Activation / physiology; Estradiol / pharmacology; Estrogens / physiology; Extracellular Signal-Regulated MAP Kinases / metabolism; Female; GTP-Binding Proteins / physiology; Intracellular Membranes / enzymology; Male; Mitogen-Activated Protein Kinase 1 / metabolism; Mitogen-Activated Protein Kinase 3 / metabolism; Neurons / metabolism; Pertussis Toxin / pharmacology; Phosphoprotein Phosphatases / metabolism; Protein Phosphatase 2; Rats; Rats, Sprague-Dawley; Signal Transduction / drug effects; Signal Transduction / physiology; Time Factors
Source: ORCID
Added: March 5, 2021

2004 journal article

Alterations of cerebellar mRNA specific for BDNF, p75NTR, and TrkB receptor isoforms occur within hours of ethanol administration to 4-day-old rat pups

Developmental Brain Research, 151(1-2), 99–109.

By: Y. Ge*, S. Belcher* & K. Light*

co-author countries: United States of America 🇺🇸

Contributors: Y. Ge*, S. Belcher* & K. Light*

author keywords: Purkinje cell; TrkB isoform; ethanol exposure; RT-PCR; mRNA; neurotrophin; cerebellum; toxicity; apoptosis; BDNF signaling
MeSH headings : Analysis of Variance; Animals; Animals, Newborn; Brain-Derived Neurotrophic Factor / genetics; Brain-Derived Neurotrophic Factor / metabolism; Central Nervous System Depressants / pharmacology; Cerebellum / drug effects; Cerebellum / metabolism; Dose-Response Relationship, Drug; Ethanol / pharmacology; Female; Male; Pregnancy; RNA, Messenger / drug effects; RNA, Messenger / metabolism; Rats; Rats, Sprague-Dawley; Receptor, Nerve Growth Factor; Receptor, trkB / genetics; Receptor, trkB / metabolism; Receptors, Nerve Growth Factor / genetics; Receptors, Nerve Growth Factor / metabolism; Reverse Transcriptase Polymerase Chain Reaction / methods; Time Factors
Sources: Crossref, ORCID
Added: August 28, 2020

2004 journal article

Altered expression of Bcl2, Bad and Bax mRNA occurs in the rat cerebellum within hours after ethanol exposure on postnatal day 4 but not on postnatal day 9

Molecular Brain Research, 129(1-2), 124–134.

By: Y. Ge*, S. Belcher*, D. Pierce* & K. Light*

co-author countries: United States of America 🇺🇸

Contributors: Y. Ge*, S. Belcher*, D. Pierce* & K. Light*

author keywords: apoptosis; Bcl2; Bad; Bax; RT-PCR; Purkinje; cerebellum; ethanol; mRNA
MeSH headings : Actins / metabolism; Animals; Animals, Newborn; Apoptosis / drug effects; Apoptosis / physiology; Calbindins; Carrier Proteins / genetics; Carrier Proteins / metabolism; Cerebellum / cytology; Cerebellum / drug effects; Cerebellum / physiology; Dose-Response Relationship, Drug; Ethanol / administration & dosage; Ethanol / blood; Ethanol / pharmacology; Female; Humans; Male; Pregnancy; Proto-Oncogene Proteins c-bcl-2 / genetics; Proto-Oncogene Proteins c-bcl-2 / metabolism; RNA, Messenger / metabolism; Rats; Rats, Sprague-Dawley; S100 Calcium Binding Protein G / metabolism; bcl-2-Associated X Protein; bcl-Associated Death Protein
Sources: Crossref, ORCID
Added: August 28, 2020

2004 journal article

Detection of Purkinje cell loss following drug exposures to developing rat pups using reverse transcriptase-polymerase chain reaction (RT-PCR) analysis for calbindin-D28k mRNA expression

Toxicology Letters, 150(3), 325–334.

By: Y. Ge*, S. Belcher*, D. Pierce* & K. Light*

co-author countries: United States of America 🇺🇸

Contributors: Y. Ge*, S. Belcher*, D. Pierce* & K. Light*

MeSH headings : Administration, Oral; Animals; Animals, Newborn; Calbindin 1; Calbindins; Cell Count; Dose-Response Relationship, Drug; Ethanol / toxicity; Female; Male; Pregnancy; Prenatal Exposure Delayed Effects; Purkinje Cells / cytology; Purkinje Cells / drug effects; Purkinje Cells / metabolism; RNA, Messenger / biosynthesis; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; S100 Calcium Binding Protein G / biosynthesis; Valproic Acid / toxicity
Sources: Crossref, ORCID
Added: January 21, 2021

2004 journal article

Estrogen receptor expression in a human primitive neuroectodermal tumor cell line from the cerebral cortex: estrogen stimulates rapid ERK1/2 activation and receptor-dependent cell migration

Biochemical and Biophysical Research Communications, 319(3), 753–758.

By: M. Kirby*, A. Zsarnovszky* & S. Belcher*

co-author countries: United States of America 🇺🇸

Contributors: M. Kirby*, A. Zsarnovszky* & S. Belcher*

author keywords: ER alpha; ER beta; ERK1/2; estrogen; estrogen receptor; growth; hormone responsive; MAPK; migration; non-genomic; PNET; signal transduction
MeSH headings : Animals; Brain Neoplasms / metabolism; Cell Line, Tumor; Cell Movement / physiology; Cerebral Cortex / metabolism; Cerebral Cortex / pathology; Enzyme Activation; Estrogens / metabolism; Humans; MAP Kinase Signaling System / physiology; Mitogen-Activated Protein Kinase 1 / metabolism; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases / metabolism; Neuroectodermal Tumors, Primitive / metabolism; Receptors, Estrogen / metabolism; Transcriptional Activation
Sources: Crossref, ORCID
Added: January 21, 2021

2004 journal article

Spatial, temporal, and cellular distribution of the activated extracellular signal regulated kinases 1 and 2 in the developing and mature rat cerebellum

Developmental Brain Research, 150(2), 199–209.

By: A. Zsarnovszky* & S. Belcher*

co-author countries: United States of America 🇺🇸

Contributors: A. Zsarnovszky* & S. Belcher*

author keywords: neurotransmitters, modulators, transporters and receptors; second messengers and phosphorylation; Bergmann glia; cerebellum; development; active EPK1/2; glia; granule cell; neuron; immunohistochemistry; kinase; MAPK; Purkinje cell; signal transduction
MeSH headings : Analysis of Variance; Animals; Animals, Newborn; Cell Count / methods; Cerebellum / enzymology; Cerebellum / growth & development; Cerebellum / metabolism; Glial Fibrillary Acidic Protein / metabolism; Immunohistochemistry / methods; Indoles / metabolism; Mitogen-Activated Protein Kinase 1 / metabolism; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases / metabolism; Purkinje Cells / metabolism; Rats; Rats, Sprague-Dawley
Sources: Crossref, ORCID
Added: August 28, 2020

2003 journal article

Estrogens and ICI182,780 (Faslodex) modulate mitosis and cell death in immature cerebellar neurons via rapid activation of p44/p42 mitogen-activated protein kinase

Journal of Neuroscience, 23(12), 4984–4995. http://www.scopus.com/inward/record.url?eid=2-s2.0-0038790428&partnerID=MN8TOARS

By: J. Wong, H. Le, A. Zsarnovszky & S. Belcher

Contributors: J. Wong, H. Le, A. Zsarnovszky & S. Belcher

Source: ORCID
Added: March 5, 2021

2002 journal article

Estrogen regulates GFAP-expression in specific subnuclei of the female rat interpeduncular nucleus: A potential role for estrogen receptor β

Brain Research, 958(2), 488–496.

By: A. Zsarnovszky*, T. Smith*, F. Hajos* & S. Belcher*

co-author countries: Hungary 🇭🇺 United States of America 🇺🇸

Contributors: A. Zsarnovszky*, T. Smith*, F. Hajos* & S. Belcher*

author keywords: astrocyte; estrogen; estrogen receptor betas; glia, glial fibrillary acidic protein immunohistochemistry; interpeduncular nucleus
MeSH headings : Animals; Estradiol / pharmacology; Estrogen Receptor beta; Estrogens / pharmacology; Female; Glial Fibrillary Acidic Protein / analysis; Glial Fibrillary Acidic Protein / biosynthesis; Mesencephalon / chemistry; Mesencephalon / drug effects; Mesencephalon / metabolism; Ovariectomy; Rats; Rats, Sprague-Dawley; Receptors, Estrogen / analysis; Receptors, Estrogen / physiology
Source: ORCID
Added: March 5, 2021

2002 journal article

Ethanol-induced alterations of neurotrophin receptor expression on Purkinje cells in the neonatal rat cerebellum

Brain Research, 924(1), 71–81.

By: K. Light*, D. Brown*, B. Newton*, S. Belcher* & C. Kane*

co-author countries: United States of America 🇺🇸

Contributors: K. Light*, D. Brown*, B. Newton*, S. Belcher* & C. Kane*

author keywords: cerebellum; truncated TrkB; TrkC; ethanol exposure; immunohistochemical
MeSH headings : Alcohol-Induced Disorders, Nervous System / metabolism; Alcohol-Induced Disorders, Nervous System / physiopathology; Animals; Brain-Derived Neurotrophic Factor / metabolism; Cell Differentiation / drug effects; Cell Differentiation / physiology; Cerebellar Cortex / drug effects; Cerebellar Cortex / growth & development; Cerebellar Cortex / pathology; Ethanol / pharmacology; Female; Fetal Alcohol Spectrum Disorders / metabolism; Fetal Alcohol Spectrum Disorders / physiopathology; Immunohistochemistry; Male; Nerve Degeneration / chemically induced; Nerve Degeneration / metabolism; Nerve Degeneration / physiopathology; Nerve Growth Factors / metabolism; Neurotrophin 3 / metabolism; Pregnancy; Purkinje Cells / drug effects; Purkinje Cells / metabolism; Purkinje Cells / pathology; Rats; Rats, Sprague-Dawley; Receptor, trkB / metabolism; Receptor, trkC / metabolism; Receptors, Nerve Growth Factor / drug effects; Receptors, Nerve Growth Factor / metabolism
Source: ORCID
Added: March 5, 2021

2002 journal article

Time course and manner of Purkinje neuron death following a single ethanol exposure on postnatal day 4 in the developing rat

Neuroscience, 114(2), 327–337.

By: K. Light*, S. Belcher* & D. Pierce*

co-author countries: United States of America 🇺🇸

Contributors: K. Light*, S. Belcher* & D. Pierce*

author keywords: cerebellum; neuronal development; apoptosis; caspase-3; cytochrome c
MeSH headings : Alcohol-Induced Disorders, Nervous System / metabolism; Alcohol-Induced Disorders, Nervous System / pathology; Alcohol-Induced Disorders, Nervous System / physiopathology; Animals; Animals, Newborn; Apoptosis / drug effects; Apoptosis / physiology; Calbindin 1; Calbindins; Caspase 3; Caspases / drug effects; Caspases / metabolism; Cerebellar Cortex / drug effects; Cerebellar Cortex / growth & development; Cerebellar Cortex / pathology; Cytochrome c Group / drug effects; Cytochrome c Group / metabolism; Drug Administration Schedule; Ethanol / toxicity; Female; Fetal Alcohol Spectrum Disorders / metabolism; Fetal Alcohol Spectrum Disorders / pathology; Fetal Alcohol Spectrum Disorders / physiopathology; Immunohistochemistry; In Situ Nick-End Labeling; Male; Mitochondria / drug effects; Mitochondria / metabolism; Mitochondria / pathology; Nerve Degeneration / chemically induced; Nerve Degeneration / metabolism; Nerve Degeneration / physiopathology; Pregnancy; Prenatal Exposure Delayed Effects; Purkinje Cells / drug effects; Purkinje Cells / metabolism; Purkinje Cells / pathology; Rats; Rats, Sprague-Dawley; S100 Calcium Binding Protein G / metabolism; Time Factors
Source: ORCID
Added: March 5, 2021

2001 journal article

Early postnatal ethanol exposure selectively decreases BDNF and truncated TrkB-T2 receptor mRNA expression in the rat cerebellum

Molecular Brain Research, 93(1), 46–55.

By: K. Light*, Y. Ge* & S. Belcher*

co-author countries: United States of America 🇺🇸

Contributors: K. Light*, Y. Ge* & S. Belcher*

author keywords: cerebellum; truncated TrkB; TrkC; ethanol-exposure; RT-PCR; mRNA
MeSH headings : Actins / genetics; Animals; Animals, Newborn; Brain-Derived Neurotrophic Factor / genetics; Central Nervous System Depressants / pharmacology; Cerebellum / drug effects; Cerebellum / physiology; DNA Primers; Ethanol / pharmacology; Female; Gene Expression Regulation, Developmental / drug effects; Isomerism; Pregnancy; RNA, Messenger / analysis; Rats; Rats, Sprague-Dawley; Receptor, trkB / chemistry; Receptor, trkB / genetics; Receptor, trkC / genetics; Reverse Transcriptase Polymerase Chain Reaction
Source: ORCID
Added: March 5, 2021

2001 journal article

Estrogen receptor β immunoreactivity in differentiating cells of the developing rat cerebellum

Journal of Comparative Neurology, 430(3), 396–409.

By: R. Jakab*, J. Wong* & S. Belcher*

co-author countries: United States of America 🇺🇸

Contributors: R. Jakab*, J. Wong* & S. Belcher*

author keywords: differentiation; development; glia; granule cells; growth; immunocytochemistry; migration; neurons; Purkinje cells
Source: ORCID
Added: March 5, 2021

2001 journal article

Estrogenic actions in the brain: Estrogen, phytoestrogens, and rapid intracellular signaling mechanisms

Journal of Pharmacology and Experimental Therapeutics, 299(2), 408–414. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034768705&partnerID=MN8TOARS

By: S. Belcher & A. Zsarnovszky

Contributors: S. Belcher & A. Zsarnovszky

Source: ORCID
Added: March 5, 2021

2001 journal article

Identification of a developmental gradient of estrogen receptor expression and cellular localization in the developing and adult female rat primary somatosensory cortex

Developmental Brain Research, 129(1), 39–46.

By: A. Zsarnovszky* & S. Belcher*

co-author countries: United States of America 🇺🇸

Contributors: A. Zsarnovszky* & S. Belcher*

author keywords: barrel; cortex; development; estrogen; estrogen receptor; immunohistochemistry; posteromedial barrel subfield; somatosensory
MeSH headings : Animals; Antibodies; Estrogens / metabolism; Female; Immunohistochemistry; Neurons / chemistry; Neurons / metabolism; Rats; Rats, Sprague-Dawley; Receptors, Estrogen / analysis; Receptors, Estrogen / biosynthesis; Receptors, Estrogen / immunology; Somatosensory Cortex / cytology; Somatosensory Cortex / growth & development; Somatosensory Cortex / metabolism
Source: ORCID
Added: March 5, 2021

2001 journal article

Simplified serum- and steroid-free culture conditions for high-throughput viability analysis of primary cultures of cerebellar granule neurons

Journal of Neuroscience Methods, 110(1-2), 45–55.

By: J. Wong*, P. Kennedy* & S. Belcher*

co-author countries: United States of America 🇺🇸

Contributors: J. Wong*, P. Kennedy* & S. Belcher*

author keywords: cell culture; cerebellum; excitotoxicity; glutamate; LDH release; MK-801; MTT; neuron; neuroprotection; neurotoxicity; reactive oxygen
MeSH headings : Animals; Animals, Newborn; Cell Culture Techniques / instrumentation; Cell Culture Techniques / methods; Cell Survival / drug effects; Cell Survival / physiology; Cells, Cultured / cytology; Cells, Cultured / drug effects; Cells, Cultured / enzymology; Cerebellar Cortex / cytology; Cerebellar Cortex / drug effects; Cerebellar Cortex / enzymology; Coloring Agents / metabolism; Culture Media, Serum-Free / pharmacology; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists / pharmacology; Female; Glutamic Acid / toxicity; L-Lactate Dehydrogenase / metabolism; Male; Neurons / cytology; Neurons / drug effects; Neurons / enzymology; Neurophysiology / instrumentation; Neurophysiology / methods; Neuroprotective Agents / pharmacology; Oxidative Stress / drug effects; Oxidative Stress / physiology; Rats; Rats, Sprague-Dawley; Steroids / pharmacology; Tetrazolium Salts / metabolism; Thiazoles / metabolism
Source: ORCID
Added: March 5, 2021

1999 journal article

Regulated expression of estrogen receptor α and β mRNA in granule cells during development of the rat cerebellum

Developmental Brain Research, 115(1), 57–69.

By: S. Belcher*

co-author countries: United States of America 🇺🇸

Contributors: S. Belcher*

author keywords: alternative splicing; cerebellum; estrogen receptor; granule cell; mRNA expression; RT-PCR
MeSH headings : Alternative Splicing; Animals; Cerebellum / cytology; Cerebellum / growth & development; Cerebellum / metabolism; Estrogen Receptor alpha; Estrogen Receptor beta; Genetic Code; Neurons / metabolism; RNA, Messenger / genetics; Rats; Rats, Sprague-Dawley; Receptors, Estrogen / genetics; Reverse Transcriptase Polymerase Chain Reaction
Source: ORCID
Added: March 5, 2021

1998 journal article

High-affinity kainate-type ion channels in rat cerebellar granule cells

Journal of Physiology, 510(2), 401–420.

By: K. Pemberton*, S. Belcher*, J. Ripellino* & J. Howe*

co-author countries: United States of America 🇺🇸

Contributors: K. Pemberton*, S. Belcher*, J. Ripellino* & J. Howe*

MeSH headings : Animals; Cell Line; Cerebellum / cytology; Cerebellum / drug effects; Cerebellum / metabolism; Concanavalin A / pharmacology; Electric Stimulation; Electrophysiology; Ion Channels / drug effects; Ion Channels / genetics; Ion Channels / metabolism; Membrane Potentials / physiology; Patch-Clamp Techniques; Precipitin Tests; Rats; Receptors, AMPA / antagonists & inhibitors; Receptors, Kainic Acid / biosynthesis; Receptors, Kainic Acid / drug effects; Receptors, Kainic Acid / genetics; Receptors, Kainic Acid / metabolism; Reverse Transcriptase Polymerase Chain Reaction
Source: ORCID
Added: March 5, 2021

1998 journal article

Localization of the m2 muscarinic acetylcholine receptor protein and mRNA in cortical neurons of the normal and cholinergically deafferented rhesus monkey

Journal of Comparative Neurology, 390(1), 112–132.

By: L. Mrzljak*, A. Levey*, S. Belcher* & P. Goldman-Rakic*

co-author countries: United States of America 🇺🇸

Contributors: L. Mrzljak*, A. Levey*, S. Belcher* & P. Goldman-Rakic*

Source: ORCID
Added: March 5, 2021

1998 journal article

Mutant alleles of the MRS2 gene of yeast nuclear DNA suppress mutations in the catalytic core of a mitochondrial group II intron

Journal of Molecular Biology, 282(3), 525–541.

By: U. Schmidt*, I. Maue*, K. Lehmann*, S. Belcher*, U. Stahl* & P. Perlman*

co-author countries: Germany 🇩🇪 United States of America 🇺🇸

Contributors: U. Schmidt*, I. Maue*, K. Lehmann*, S. Belcher*, U. Stahl* & P. Perlman*

author keywords: group II introns; yeast mitochondria; splicing; MRS2 gene; dominant negative
MeSH headings : Alleles; Amino Acid Sequence; DNA, Fungal / genetics; DNA, Mitochondrial / genetics; Gene Expression Regulation, Fungal; Genes, Fungal; Genes, Suppressor; Introns / genetics; Ion Channels; Mitochondrial Proteins; Molecular Sequence Data; Mutation; Nuclear Proteins / genetics; Saccharomyces cerevisiae / genetics; Saccharomyces cerevisiae / ultrastructure; Saccharomyces cerevisiae Proteins
Source: ORCID
Added: March 5, 2021

1997 journal article

Characterization of RNA editing of the glutamate-receptor subunits GluR5 and GluR6 in granule cells during cerebellar development

Molecular Brain Research, 52(1), 130–138.

By: S. Belcher* & J. Howe*

co-author countries: United States of America 🇺🇸

Contributors: S. Belcher* & J. Howe*

author keywords: glutamate receptor; kainate; RNA editing; cerebellum; granule cell; development
MeSH headings : Adenosine Deaminase / biosynthesis; Animals; Cerebellum / cytology; Cerebellum / metabolism; Molecular Sequence Data; Neurons / metabolism; RNA Editing; Rats; Receptors, Kainic Acid / genetics
Source: ORCID
Added: March 5, 2021

1996 journal article

A new sodium channel α-subunit gene (Scn9a) from Schwann cells maps to the Scn1a, Scn2a, Scn3a cluster of mouse chromosome 2

Genomics, 36(1), 202–205.

By: M. Beckers*, E. Ernst*, S. Belcher*, J. Howe*, R. Levenson* & P. Gros*

co-author countries: Canada 🇨🇦 United States of America 🇺🇸

Contributors: M. Beckers*, E. Ernst*, S. Belcher*, J. Howe*, R. Levenson* & P. Gros*

MeSH headings : Animals; Chromosome Mapping; Crosses, Genetic; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Multigene Family / genetics; Muridae; Polymorphism, Restriction Fragment Length; Rabbits; Rats; Schwann Cells; Sodium Channels / genetics; Species Specificity
Source: ORCID
Added: March 5, 2021

1996 journal article

Cloning of the cDNA encoding the sodium channel β1 subunit from rabbit

Gene, 170(2), 285–286.

By: S. Belcher* & J. Howe*

co-author countries: United States of America 🇺🇸

Contributors: S. Belcher* & J. Howe*

MeSH headings : Amino Acid Sequence; Animals; Base Sequence; Cloning, Molecular; DNA, Complementary; Humans; Molecular Sequence Data; Rabbits; Rats; Sodium Channels / genetics
Source: ORCID
Added: March 5, 2021

1996 book

[24] Transformation of Saccharomyces cerevisiae mitochondria using the biolistic gun

In Methods in Enzymology (Vol. 264, pp. 265–278). http://www.scopus.com/inward/record.url?eid=2-s2.0-0029873586&partnerID=MN8TOARS

By: R. Butow, R. Henke, J. Moran, S. Belcher & P. Perlman

Contributors: R. Butow, R. Henke, J. Moran, S. Belcher & P. Perlman

Source: ORCID
Added: March 5, 2021

1995 journal article

Cloning of a sodium channel α subunit from rabbit Schwann cells

Proceedings of the National Academy of Sciences of the United States of America, 92(24), 11034–11038.

By: S. Belcher*, C. Zerillo*, R. Levenson*, J. Ritchie* & J. Howe*

co-author countries: United States of America 🇺🇸

Contributors: S. Belcher*, C. Zerillo*, R. Levenson*, J. Ritchie* & J. Howe*

MeSH headings : Alternative Splicing; Animals; Base Sequence; Brain Chemistry; Cloning, Molecular; DNA Primers / chemistry; DNA, Complementary / genetics; Gene Expression; Genes; Molecular Sequence Data; Muscles / chemistry; Nerve Tissue Proteins / genetics; RNA, Messenger / genetics; Rabbits; Rats; Schwann Cells / chemistry; Sequence Alignment; Sequence Homology, Amino Acid; Sodium Channels / genetics
Source: ORCID
Added: March 5, 2021

1995 journal article

Studies of point mutants define three essential paired nucleotides in the domain 5 substructure of a group II intron

Molecular and Cellular Biology, 15(8), 4479–4488.

By: S. Boulanger*, S. Belcher*, U. Schmidt*, S. Dib-Hajj*, T. Schmidt* & P. Perlman*

co-author countries: United States of America 🇺🇸

Contributors: S. Boulanger*, S. Belcher*, U. Schmidt*, S. Dib-Hajj*, T. Schmidt* & P. Perlman*

MeSH headings : Base Composition; Base Sequence; Conserved Sequence; DNA Mutational Analysis; Electron Transport Complex IV / genetics; Introns / genetics; Molecular Sequence Data; Phenotype; Point Mutation; RNA Splicing; RNA, Catalytic / genetics; Saccharomyces cerevisiae / genetics; Structure-Activity Relationship; Suppression, Genetic
Source: ORCID
Added: March 5, 2021

1995 journal article

The responsiveness of a tetracycline-sensitive expression system differs in different cell lines

Journal of Biological Chemistry, 270(23), 14168–14174.

By: J. Howe*, B. Skryabin*, S. Belcher*, C. Zerillo* & C. Schmauss*

co-author countries: United States of America 🇺🇸

Contributors: J. Howe*, B. Skryabin*, S. Belcher*, C. Zerillo* & C. Schmauss*

MeSH headings : Animals; Cell Line; Gene Expression Regulation / drug effects; Humans; RNA, Messenger / analysis; Rats; Receptors, Dopamine / genetics; Receptors, Dopamine D2; Receptors, Dopamine D3; Tetracycline / pharmacology; Transfection
Source: ORCID
Added: March 5, 2021

1994 journal article

Splicing defective mutants of the COXI gene of yeast mitochondrial DNA: Initial definition of the maturase domain of the group II intron AI2

Nucleic Acids Research, 22(11), 2057–2064.

By: J. Moran*, K. Mecklenburg*, P. Sass*, S. Belcher*, D. Mahnke*, A. Lewin*, P. Perlman*

co-author countries: United States of America 🇺🇸

Contributors: J. Moran*, K. Mecklenburg*, P. Sass*, S. Belcher*, D. Mahnke*, A. Lewin*, P. Perlman*

MeSH headings : Base Sequence; DNA, Fungal; DNA, Mitochondrial / genetics; Electron Transport Complex IV / genetics; Endoribonucleases / metabolism; Genes, Fungal; Genetic Complementation Test; Introns; Molecular Sequence Data; Mutation; Nucleotidyltransferases / metabolism; Open Reading Frames; RNA Splicing / genetics; RNA, Fungal; Restriction Mapping; Saccharomyces cerevisiae / genetics
Source: ORCID
Added: March 5, 2021

1993 journal article

Mutation of the conserved first nucleotide of a group II intron from yeast mitochondrial DNA reduces the rate but allows accurate splicing

Journal of Biological Chemistry, 268(16), 11929–11938. http://www.scopus.com/inward/record.url?eid=2-s2.0-0027156992&partnerID=MN8TOARS

By: C. Peebles, S. Belcher, M. Zhang, R. Dietrich & P. Perlman

Contributors: C. Peebles, S. Belcher, M. Zhang, R. Dietrich & P. Perlman

Source: ORCID
Added: March 5, 2021

1992 journal article

A maturase-encoding group MA intron of yeast mitochondria self-splices in vitro

Nucleic Acids Research, 20(7), 1747–1754.

By: S. Hebbar, S. Belcher* & P. Perlman*

co-author countries: United States of America 🇺🇸

Contributors: S. Hebbar, S. Belcher* & P. Perlman*

MeSH headings : Base Sequence; DNA, Mitochondrial / genetics; Introns / genetics; Mitochondria / enzymology; Molecular Sequence Data; RNA Splicing / genetics; RNA, Catalytic / metabolism; Yeasts / genetics
Source: ORCID
Added: March 5, 2021

Employment

Updated: July 20th, 2019 11:01

2016 - present

North Carolina State University Raleigh, NC, US
Professor Biological Science

Education

Updated: July 20th, 2019 11:05

1990 - 1993

University of Texas Southwestern Department of Biochemistry Dallas, TX, US
PhD Biochemistry