Works (90)

Updated: April 11th, 2023 10:13

2022 journal article

A Critical Review and Meta-Analysis of Impacts of Per- and Polyfluorinated Substances on the Brain and Behavior

Frontiers in Toxicology, 4.

By: H. Starnes n, K. Rock n, T. Jackson n & S. Belcher

Source: ORCID
Added: January 6, 2023

2022 journal article

Blood concentrations of per- and polyfluoroalkyl substances are associated with autoimmune-like effects in American alligators from Wilmington, North Carolina

Frontiers in Toxicology, 4.

By: T. Guillette n, T. Jackson, M. Guillette, J. McCord & S. Belcher

Source: ORCID
Added: January 6, 2023

2022 article

Comparative assessment of blood mercury in American alligators (Alligator mississippiensis) from Coastal North Carolina and Florida

Belcher, S. M., Guillette, M. P., Robb, F., & Rock, K. D. (2022, August 3). ECOTOXICOLOGY, Vol. 8.

By: S. Belcher, M. Guillette, F. Robb* & K. Rock

author keywords: Bioaccumulation; Biomonitoring; Ecotoxicology; Mercury; Metals; Reptile
Sources: ORCID, Web Of Science
Added: August 3, 2022

2022 article

Gestational Cd Exposure in the CD-1 Mouse Sex-Specifically Disrupts Essential Metal Ion Homeostasis

Jackson, T. W., Baars, O., & Belcher, S. M. (2022, February 25). TOXICOLOGICAL SCIENCES, Vol. 2.

By: T. Jackson, O. Baars & S. Belcher

author keywords: gestation; epigenetic; essential metals; metallothionein; placenta
Sources: ORCID, Web Of Science
Added: February 26, 2022

2022 article

The imprinted gene Zac1 regulates steatosis in developmental cadmium-induced nonalcoholic fatty liver disease

Riegl, S. D., Starnes, C., Jima, D. D., Baptissart, M., Diehl, A. M., Belcher, S. M., & Cowley, M. (2022, October 6). TOXICOLOGICAL SCIENCES, Vol. 10.

By: S. Riegl n, C. Starnes n, D. Jima, M. Baptissart, A. Diehl*, S. Belcher, M. Cowley

author keywords: nonalcoholic fatty liver disease; developmental toxicology; epigenetics; cadmium; genomic imprinting; developmental programming
Sources: ORCID, Web Of Science
Added: October 29, 2022

2022 journal article

Utilizing Pine Needles to Temporally and Spatially Profile Per- and Polyfluoroalkyl Substances (PFAS)

ENVIRONMENTAL SCIENCE & TECHNOLOGY, 56(6), 3441–3451.

By: K. Kirkwood, J. Fleming, H. Nguyen n, D. Reif, E. Baker & S. Belcher

author keywords: Biomonitoring; contamination; per- and polyfluoroalkyl substances; fluoroethers; ion mobility; mass spectrometry; PFAS
Sources: ORCID, Web Of Science
Added: February 18, 2022

2021 article

Gestational Cd Exposure in the CD-1 Mouse Sex-Specifically Disrupts Essential Metal Ion Homeostasis

Jackson, T. W., Baars, O., & Belcher, S. M. (2021, November 7). (Vol. 11). Vol. 11.

By: T. Jackson n, O. Baars & S. Belcher

Source: ORCID
Added: November 8, 2021

2021 journal article

Key Characteristics of Cardiovascular Toxicants

ENVIRONMENTAL HEALTH PERSPECTIVES, 129(9).

By: L. Lind*, J. Araujo*, A. Barchowsky*, S. Belcher, B. Berridge, N. Chiamvimonvat*, W. Chiu*, V. Cogliano* ...

Sources: Web Of Science, ORCID
Added: November 8, 2021

2021 journal article

Rapid Characterization of Human Serum Albumin Binding for Per- and Polyfluoroalkyl Substances Using Differential Scanning Fluorimetry

ENVIRONMENTAL SCIENCE & TECHNOLOGY, 55(18), 12291–12301.

By: T. Jackson, C. Scheibly, M. Polera & S. Belcher

author keywords: alcohols; carboxylic acids; fluorocarbons; perfluorocarbons; protein; sulfonic acids; telomer; thermal stability; toxicokinetic
Sources: ORCID, Web Of Science
Added: September 9, 2021

2021 article

Utilizing Pine Needles to Temporally and Spatially Profile Per- and Polyfluoroalkyl Substances

Kirkwood, K. I., Fleming, J., Nguyen, H., Reif, D. M., Baker, E. S., & Belcher, S. M. (2021, August 26). (Vol. 8). Vol. 8.

By: K. Kirkwood n, J. Fleming n, H. Nguyen n, D. Reif, E. Baker n & S. Belcher

Source: ORCID
Added: August 27, 2021

2020 journal article

Data integration, analysis, and interpretation of eight academic CLARITY-BPA studies

REPRODUCTIVE TOXICOLOGY, 98, 29–60.

By: J. Heindel*, S. Belcher, J. Flaws*, G. Prins*, S. Ho*, J. Mao*, H. Patisaul, W. Ricke* ...

author keywords: CLARITY-BPA; Guideline study; Bisphenol A; EDC; Endocrine disruptor; GLP; Systemic effects
Sources: Web Of Science, ORCID
Added: January 19, 2021

2020 journal article

Elevated levels of per- and polyfluoroalkyl substances in Cape Fear River Striped Bass (Morone saxatilis) are associated with biomarkers of altered immune and liver function

ENVIRONMENT INTERNATIONAL, 136.

By: T. Guillette, J. McCord, M. Guillette n, M. Polera, K. Rachels*, C. Morgeson*, N. Kotlarz, D. Knappe ...

Sources: Web Of Science, ORCID
Added: March 2, 2020

2020 journal article

Gestational Cd Exposure in the CD-1 Mouse Induces Sex-Specific Hepatic Insulin Insensitivity, Obesity, and Metabolic Syndrome in Adult Female Offspring

TOXICOLOGICAL SCIENCES, 178(2), 264–280.

By: T. Jackson, G. Ryherd n, C. Scheibly n, A. Sasser n, T. Guillette n & S. Belcher

author keywords: cadmium; diabetes mellitus type 2; endocrine disruption; insulin resistance; metabolic; nonalcoholic fatty liver disease; retinoic acid
Sources: Web Of Science, ORCID
Added: February 15, 2021

2020 article

Heterozygous mutation of Sonic Hedgehog receptor (Ptch) drives cerebellar overgrowth and sex-specifically alters hippocampal and cortical layer structure, activity, and social behavior in female mice

Jackson, T. W., Bendfeldt, G. A., Beam, K. A., Rock, K. D., & Belcher, S. M. (2020, January 25). (Vol. 1). Vol. 1.

By: T. Jackson n, G. Bendfeldt n, K. Beam n, K. Rock n & S. Belcher

Source: ORCID
Added: March 5, 2021

2020 journal article

Heterozygous mutation of sonic hedgehog receptor (Ptch1) drives cerebellar overgrowth and sex-specifically alters hippocampal and cortical layer structure, activity, and social behavior in female mice

NEUROTOXICOLOGY AND TERATOLOGY, 78.

By: T. Jackson, G. Bendfeldt n, K. Beam n, K. Rock & S. Belcher

author keywords: Cerebellum; Cortex; Holoprosencephaly; Hyperactivity; Medial prefrontal cortex; Medulloblastoma; Sex differences
Sources: Web Of Science, ORCID
Added: April 14, 2020

2019 journal article

Elevated metabolites of acetaminophen in cord blood of children with obesity

PEDIATRIC OBESITY, 14(1).

By: P. Sorrow, R. Maguire, S. Murphy*, S. Belcher & C. Hoyo

author keywords: Acetaminophen; children; metabolomics; obesity
Sources: Web Of Science, ORCID
Added: January 7, 2019

2019 journal article

Endocrine Disruption and Reproductive Pathology

TOXICOLOGIC PATHOLOGY, 47(8), 1049–1071.

By: S. Belcher, J. Cline*, J. Conley*, S. Groeters*, W. Jefferson*, M. Law, E. Mackey, A. Suen* ...

author keywords: endocrine disrupters; environmental toxicology; fish pathology; hormonal carcinogenesis; reproductive system; nonhuman primate; rodent pathology
Sources: Web Of Science, ORCID
Added: December 30, 2019

2019 journal article

Maternal cadmium exposure in the mouse leads to increased heart weight at birth and programs susceptibility to hypertension in adulthood

SCIENTIFIC REPORTS, 9(1).

By: K. Hudson n, S. Belcher & M. Cowley

Sources: Web Of Science, ORCID
Added: October 7, 2019

2018 journal article

CLARITY-BPA academic laboratory studies identify consistent low-dose Bisphenol A effects on multiple organ systems

Basic & Clinical Pharmacology & Toxicology, 125(S3), 14–31.

By: G. Prins*, H. Patisaul, S. Belcher & L. Vandenberg*

author keywords: Bisphenol A; CLARITY-BPA; endocrine disruptor; endocrine-disrupting chemical; oestrogen
Sources: ORCID, Crossref
Added: August 17, 2019

2018 article

CLARITY-BPA: Heart (Belcher)

Belcher, S. (2018, August). Chemical Effects in Biological Systems (CEBS).

By: S. Belcher

Source: ORCID
Added: March 5, 2021

2018 journal article

Duality of estrogen receptor beta action in cancer progression

CURRENT OPINION IN PHARMACOLOGY, 41, 66–73.

By: T. Guillette, T. Jackson & S. Belcher

Sources: Web Of Science, ORCID
Added: October 16, 2018

2017 journal article

Effects of bisphenol A on incidence and severity of cardiac lesions in the NCTR-Sprague-Dawley rat: A CLARITY-BPA study

Toxicology Letters, 275, 123–135.

By: R. Gear*, J. Kendziorski* & S. Belcher

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2017 book

Endocrine Disruptors, Brain, and Behavior

In Oxford Scholarship Online.

By: H. Patisaul & S. Belcher

Source: ORCID
Added: March 5, 2021

2017 journal article

Estrogen and soy isoflavonoids decrease sensitivity of medulloblastoma and central nervous system primitive neuroectodermal tumor cells to chemotherapeutic cytotoxicity

BMC PHARMACOLOGY & TOXICOLOGY, 18(1).

By: S. Belcher, C. Burton, C. Cookman, M. Kirby, G. Miranda, F. Saeed, K. Wray

author keywords: Chemotherapy; Cytoprotection; Concentration-response; Estrogen; In vitro; Isoflavones; Medulloblastoma; Phytoestrogen
Sources: Web Of Science, ORCID
Added: August 6, 2018

2017 journal article

Gestational high-fat diet and bisphenol A exposure heightens mammary cancer risk

Endocrine-Related Cancer, 24(7), 365–378.

By: Y. Leung*, V. Govindarajah*, A. Cheong*, J. Veevers*, D. Song*, R. Gear*, X. Zhu*, J. Ying* ...

author keywords: breast cancer; developmental origin of health and disease (DOHaD); RNA-seq; transcriptomics; DNA methylation; patient survival; TCGA; windows of susceptibility; in utero exposure; bisphenol A; high-butter fat diet; non-monotonic response
Source: ORCID
Added: March 5, 2021

2017 journal article

Impacts of Bisphenol A and Ethinyl Estradiol on Male and Female CD-1 Mouse Spleen

SCIENTIFIC REPORTS, 7(1).

By: R. Gear* & S. Belcher

Sources: Web Of Science, ORCID
Added: August 6, 2018

2016 journal article

Impact of Low Dose Oral Exposure to Bisphenol A (BPA) on the Neonatal Rat Hypothalamic and Hippocampal Transcriptome: A CLARITY-BPA Consortium Study

Endocrinology, 157(10), 3856–3872.

By: S. Arambula, S. Belcher, A. Planchart, S. Turner* & H. Patisaul

Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018

2015 journal article

Bisphenol a alters autonomic tone and extracellular matrix structure and induces sex-specific effects on cardiovascular function in male and female CD-1 mice

Endocrinology, 156(3), 882–895.

By: S. Belcher, R. Gear* & E. Kendig*

Source: ORCID
Added: March 5, 2021

2015 journal article

Effects of whole life exposure to Bisphenol A or 17α-ethinyl estradiol in uterus of nulligravida CD1 mice

Data in Brief, 5, 948–953.

By: J. Kendziorski* & S. Belcher

author keywords: BPA; Estrogen; EDC; endocrine disruption; Collagen; Fibrosis; Immune; Macrophage
Sources: Crossref, ORCID
Added: August 28, 2020

2015 journal article

Estrogen receptor-β up-regulates IGF1R expression and activity to inhibit apoptosis and increase growth of medulloblastoma

Endocrinology, 156(7), 2395–2408.

By: C. Cookman* & S. Belcher

Source: ORCID
Added: March 5, 2021

2015 journal article

New Master of Science program emphasizing Safety Pharmacology—Results to date

Journal of Pharmacological and Toxicological Methods, 75, 191–192.

By: A. Matlib*, S. Belcher, R. Rapoport*, R. Millard*, H. Wang* & J. Maggio*

Sources: Crossref, ORCID
Added: August 28, 2020

2015 journal article

Non-monotonic dose-response relationships and endocrine disruptors: A qualitative method of assessment -No section-

Environmental Health: A Global Access Science Source, 14(1).

By: F. Lagarde*, C. Beausoleil*, S. Belcher, L. Belzunces*, C. Emond*, M. Guerbet*, C. Rousselle*

author keywords: Endocrine disruptors; NMDR; Non-monotonic; Dose-response; Risk assessment; Bisphenol A
Source: ORCID
Added: March 5, 2021

2015 journal article

Response to the letter by Gallo D., et al

Endocrinology, 156(8), L8–L9.

By: S. Belcher

Source: ORCID
Added: March 5, 2021

2015 journal article

Strain-specific induction of endometrial periglandular fibrosis in mice exposed during adulthood to the endocrine disrupting chemical bisphenol A

Reproductive Toxicology, 58, 119–130.

By: J. Kendziorski* & S. Belcher

author keywords: BPA; Endocrine disruptor; Uterus; Mouse; Collagen; Dose response; Endometrial periglandular fibrosis; Equine endometrosis; Matrix metalloproteinase; Non-monotonic
Sources: Crossref, ORCID
Added: February 24, 2020

2014 journal article

Actions of endocrine-disrupting chemicals on stem/progenitor cells during development and disease

Endocrine-Related Cancer, 21(2).

By: E. Kopras*, V. Potluri*, M. Bermudez*, K. Williams*, S. Belcher & S. Kasper*

author keywords: endocrine disruptors; stem cell/progenitor cell; cancer stem cell; organ development; steroid hormone receptors
Source: ORCID
Added: March 5, 2021

2014 journal article

Bisphenol A and cardiometabolic risk factors in obese children

Science of The Total Environment, 470-471, 726–732.

By: N. Khalil*, J. Ebert*, L. Wang*, S. Belcher, M. Lee*, S. Czerwinski*, K. Kannan*

author keywords: Bisphenol A; Endocrine disruptor; Non-monotonic dose response; Childhood obesity; Nonalcoholic fatty liver disease; Spline analysis
Sources: Crossref, ORCID
Added: August 28, 2020

2014 journal article

Classical nuclear hormone receptor activity as a mediator of complex concentration response relationships for endocrine active compounds

Current Opinion in Pharmacology, 19, 112–119.

By: C. Cookman & S. Belcher

Sources: Crossref, ORCID
Added: August 28, 2020

2014 journal article

Editorial overview: Endocrine and metabolic diseases: Conversations on endocrine disruptors — rising above the din

Current Opinion in Pharmacology, 19, vi-vii.

By: S. Belcher

Sources: Crossref, ORCID
Added: December 21, 2020

2014 journal article

In vitro assessment of human nuclear hormone receptor activity and cytotoxicity of the flame retardant mixture FM 550 and its triarylphosphate and brominated components

Toxicology Letters, 228(2), 93–102.

By: S. Belcher, C. Cookman*, H. Patisaul & H. Stapleton*

author keywords: Apoptosis Endocrine disruptor; Flame retardant; Nuclear receptors; Obesity; Peroxisome proliferator-activated receptor
Sources: Crossref, ORCID, Web Of Science
Added: August 6, 2018

2013 journal article

Accumulation and Endocrine Disrupting Effects of the Flame Retardant Mixture Firemaster® 550 in Rats: An Exploratory Assessment

Journal of Biochemical and Molecular Toxicology, 27(2), 124–136.

By: H. Patisaul, S. Roberts*, N. Mabrey n, K. McCaffrey, R. Gear*, J. Braun*, S. Belcher, H. Stapleton*

author keywords: Anxiety; Cardiac Hypertrophy; Endocrine Disruptor; Flame Retardants; Metabolic Syndrome; Metabolism; Obesity; Obesogen; Polybrominated Diphenyl Ethers; Rodents
Sources: Crossref, ORCID, Web Of Science
Added: August 6, 2018

2013 journal article

The estrogenic content of rodent diets, bedding, cages, and water bottles and its effect on bisphenol a studies

Journal of the American Association for Laboratory Animal Science, 52(2), 130–141. http://www.scopus.com/inward/record.url?eid=2-s2.0-84875526300&partnerID=MN8TOARS

By: J. Thigpen, K. Setchell, G. Kissling, J. Locklear, G. Caviness, T. Whiteside, S. Belcher, N. Brown ...

Source: ORCID
Added: March 5, 2021

2012 journal article

Estrogen-like disruptive effects of dietary exposure to bisphenol A or 17α-ethinyl estradiol in CD1 mice

International Journal of Toxicology, 31(6), 537–550.

By: E. Kendig*, D. Buesing*, S. Christie*, C. Cookman*, R. Gear*, E. Hugo*, S. Kasper*, J. Kendziorski* ...

author keywords: Bisphenol A; diabetes; endocrine disruptor; estrogen; metabolic effects; obesity; prolactin
Source: ORCID
Added: March 5, 2021

2012 journal article

Inhibition of stathmin1 accelerates the metastatic process

Cancer Research, 72(20), 5407–5417.

By: K. Williams*, R. Ghosh*, P. Giridhar*, G. Gu*, T. Case*, S. Belcher, S. Kasper*

Source: ORCID
Added: March 5, 2021

2012 journal article

Rapid estrogen receptor-mediated mechanisms determine the sexually dimorphic sensitivity of ventricular myocytes to 17β-estradiol and the environmental endocrine disruptor bispheno A

Endocrinology, 153(2), 712–720.

By: S. Belcher, Y. Chen*, S. Yan* & H. Wang*

Source: ORCID
Added: March 5, 2021

2012 journal article

Strain specific induction of pyometra and differences in immune responsiveness in mice exposed to 17α-ethinyl estradiol or the endocrine disrupting chemical bisphenol A

Reproductive Toxicology, 34(1), 22–30.

By: J. Kendziorski*, E. Kendig*, R. Gear* & S. Belcher

author keywords: Bisphenol A; Macrophage; Pyometra; Uterus; Mouse; Estrogen; Endocrine disruptor; Immune response
Sources: Crossref, ORCID
Added: August 28, 2020

2011 journal article

Assessment of bisphenol A released from reusable plastic, aluminium and stainless steel water bottles

Chemosphere, 85(6), 943–947.

By: J. Cooper*, E. Kendig* & S. Belcher

author keywords: Bisphenol A; Copolyester; Epoxy resins; Endocrine disrupting chemicals; Polycarbonate; Water bottles
Sources: Crossref, ORCID
Added: August 28, 2020

2011 journal article

Bisphenol A and 17β-estradiol promote arrhythmia in the female heart via alteration of calcium handling

PLoS ONE, 6(9).

By: S. Yan*, Y. Chen*, M. Dong*, W. Song*, S. Belcher & H. Wang*

Source: ORCID
Added: March 5, 2021

2010 journal article

Defining hormesis: Evaluation of a complex concentration response phenomenon

International Journal of Toxicology, 29(3), 235–246.

By: E. Kendig*, H. Le* & S. Belcher

author keywords: hormesis; dose-response relationship; threshold model; beta-curve; biphasic effects; nonmonotonic; low-dose effects; subthreshold response
Source: ORCID
Added: March 5, 2021

2010 journal article

Flawed experimental design reveals the need for guidelines requiring appropriate positive controls in endocrine disruption research

Toxicological Sciences, 115(2), 612–613.

By: F. Saal*, B. Akingbemi*, S. Belcher, D. Crain*, D. Crews*, L. Guidice*, P. Hunt*, C. Leranth* ...

Source: ORCID
Added: March 5, 2021

2010 journal article

Rapid signaling actions of environmental estrogens in developing granule cell neurons are mediated by estrogen receptor β

Endocrinology, 151(12), 5689–5699.

By: H. Le* & S. Belcher

Source: ORCID
Added: March 5, 2021

2009 journal article

Blockade of estrogen receptor signaling inhibits growth and migration of medulloblastoma

Endocrinology, 150(3), 1112–1121.

By: S. Belcher, X. Ma* & H. Le*

Source: ORCID
Added: March 5, 2021

2009 journal article

Blockade of estrogen receptor signaling to improve outlook for medulloblastoma sufferers

Future Oncology, 5(6), 751–754.

By: S. Belcher

Source: ORCID
Added: March 5, 2021

2009 journal article

Good laboratory practices: Myers et al. respond

Environmental Health Perspectives, 117(11).

By: J. Myers*, F. Vom Saal*, J. Taylor*, B. Akingbemi*, K. Arizono*, S. Belcher, T. Colborn*, I. Chahoud*

Source: ORCID
Added: March 5, 2021

2009 journal article

Why public health agencies cannot depend on good laboratory practices as a criterion for selecting data: The case of bisphenol A

Environmental Health Perspectives, 117(3), 309–315.

author keywords: bisphenol A; endocrine disruptors; FDA; Food and Drug Administration; GLP; good laboratory practices; low-dose; nonmonotonic; positive control
Source: ORCID
Added: March 5, 2021

2008 journal article

Bisphenol A is released from polycarbonate drinking bottles and mimics the neurotoxic actions of estrogen in developing cerebellar neurons

Toxicology Letters, 176(2), 149–156.

By: H. Le*, E. Carlson*, J. Chua* & S. Belcher

author keywords: BPA endocrine disruption; estrogen; neurotoxicity; non-genomic
Sources: Crossref, ORCID
Added: August 28, 2020

2008 book

Cardiovascular effects of steroidal agents

In Cardiovascular Toxicology, Fourth Edition (pp. 367–428). http://www.scopus.com/inward/record.url?eid=2-s2.0-85057367081&partnerID=MN8TOARS

By: R. Melchert, S. Belcher & R. Kennedy

Source: ORCID
Added: March 5, 2021

2008 journal article

Rapid signaling mechanisms of estrogens in the developing cerebellum

Brain Research Reviews, 57(2), 481–492.

By: S. Belcher

author keywords: cerebellum; development; ERK; estrogen; non-genomic; signal transduction
Sources: Crossref, ORCID
Added: January 21, 2021

2007 journal article

Chapel Hill bisphenol A expert panel consensus statement: Integration of mechanisms, effects in animals and potential to impact human health at current levels of exposure

Reproductive Toxicology, 24(2), 131–138.

By: F. vom Saal*, B. Akingbemi*, S. Belcher, L. Birnbaum*, D. Crain*, M. Eriksen*, F. Farabollini*, L. Guillette* ...

author keywords: bisphenol A; in vitro; in vivo; rat; mouse; aquatic animal; cancer; low dose; non-monotonic dose-response curves; developmental programming
Sources: Crossref, ORCID
Added: March 8, 2020

2007 journal article

In vitro molecular mechanisms of bisphenol A action

Reproductive Toxicology, 24(2), 178–198.

By: Y. Wetherill*, B. Akingbemi*, J. Kanno*, J. McLachlan*, A. Nadal*, C. Sonnenschein*, C. Watson*, R. Zoeller*, S. Belcher

author keywords: bisphenol A (BPA, 2,2-bis(4-hydroxyphenyl) propane; endocrine disruption; endocrine disrupting chemical (EDC); rapid signaling; estrogen receptor; androgen receptor; thyroid receptor; thyroid hormone; GPR30; non-classical membrane estrogen receptor; immune system; allergic resonse; in vitro mechanisms; cell specificity; expert panel review
Sources: Crossref, ORCID
Added: August 28, 2020

2006 journal article

Immunolocalization of ecto-nucleoside triphosphate diphosphohydrolase 3 in rat brain: Implications for modulation of multiple homeostatic systems including feeding and sleep–wake behaviors

Neuroscience, 137(4), 1331–1346.

By: S. Belcher, A. Zsarnovszky*, P. Crawford*, H. Hemani*, L. Spurling* & T. Kirley*

author keywords: nucleoside triphosphate diphosphohydrolase; NTPDase3; CD39L3; immunohistochemistry; purinergic signaling; orexin/hypocretin co-localization
Sources: Crossref, ORCID
Added: January 21, 2021

2005 journal article

Ontogeny of rapid estrogen-mediated extracellular signal-regulated kinase signaling in the rat cerebellar cortex: Potent nongenomic agonist and endocrine disrupting activity of the xenoestrogen bisphenol A

Endocrinology, 146(12), 5388–5396.

By: A. Zsarnovszky*, H. Le*, H. Wang* & S. Belcher

Source: ORCID
Added: March 5, 2021

2005 journal article

Rapid estrogenic regulation of extracellular signal-regulated kinase 1/2 signaling in cerebellar granule cells involves a G protein- and protein kinase A-dependent mechanism and intracellular activation of protein phosphatase 2A

Endocrinology, 146(12), 5397–5406.

By: S. Belcher, H. Le*, L. Spurling* & J. Wong*

Source: ORCID
Added: March 5, 2021

2004 journal article

Alterations of cerebellar mRNA specific for BDNF, p75NTR, and TrkB receptor isoforms occur within hours of ethanol administration to 4-day-old rat pups

Developmental Brain Research, 151(1-2), 99–109.

By: Y. Ge*, S. Belcher & K. Light*

author keywords: Purkinje cell; TrkB isoform; ethanol exposure; RT-PCR; mRNA; neurotrophin; cerebellum; toxicity; apoptosis; BDNF signaling
Sources: Crossref, ORCID
Added: August 28, 2020

2004 journal article

Altered expression of Bcl2, Bad and Bax mRNA occurs in the rat cerebellum within hours after ethanol exposure on postnatal day 4 but not on postnatal day 9

Molecular Brain Research, 129(1-2), 124–134.

By: Y. Ge*, S. Belcher, D. Pierce* & K. Light*

author keywords: apoptosis; Bcl2; Bad; Bax; RT-PCR; Purkinje; cerebellum; ethanol; mRNA
Sources: Crossref, ORCID
Added: August 28, 2020

2004 journal article

Detection of Purkinje cell loss following drug exposures to developing rat pups using reverse transcriptase-polymerase chain reaction (RT-PCR) analysis for calbindin-D28k mRNA expression

Toxicology Letters, 150(3), 325–334.

By: Y. Ge*, S. Belcher, D. Pierce* & K. Light*

Sources: Crossref, ORCID
Added: January 21, 2021

2004 journal article

Estrogen receptor expression in a human primitive neuroectodermal tumor cell line from the cerebral cortex: estrogen stimulates rapid ERK1/2 activation and receptor-dependent cell migration

Biochemical and Biophysical Research Communications, 319(3), 753–758.

By: M. Kirby*, A. Zsarnovszky* & S. Belcher

author keywords: ER alpha; ER beta; ERK1/2; estrogen; estrogen receptor; growth; hormone responsive; MAPK; migration; non-genomic; PNET; signal transduction
Sources: Crossref, ORCID
Added: January 21, 2021

2004 journal article

Spatial, temporal, and cellular distribution of the activated extracellular signal regulated kinases 1 and 2 in the developing and mature rat cerebellum

Developmental Brain Research, 150(2), 199–209.

By: A. Zsarnovszky* & S. Belcher

author keywords: neurotransmitters, modulators, transporters and receptors; second messengers and phosphorylation; Bergmann glia; cerebellum; development; active EPK1/2; glia; granule cell; neuron; immunohistochemistry; kinase; MAPK; Purkinje cell; signal transduction
Sources: Crossref, ORCID
Added: August 28, 2020

2003 journal article

Estrogens and ICI182,780 (Faslodex) modulate mitosis and cell death in immature cerebellar neurons via rapid activation of p44/p42 mitogen-activated protein kinase

Journal of Neuroscience, 23(12), 4984–4995. http://www.scopus.com/inward/record.url?eid=2-s2.0-0038790428&partnerID=MN8TOARS

By: J. Wong, H. Le, A. Zsarnovszky & S. Belcher

Source: ORCID
Added: March 5, 2021

2002 journal article

Estrogen regulates GFAP-expression in specific subnuclei of the female rat interpeduncular nucleus: A potential role for estrogen receptor β

Brain Research, 958(2), 488–496.

By: A. Zsarnovszky*, T. Smith*, F. Hajos* & S. Belcher

author keywords: astrocyte; estrogen; estrogen receptor betas; glia, glial fibrillary acidic protein immunohistochemistry; interpeduncular nucleus
Source: ORCID
Added: March 5, 2021

2002 journal article

Ethanol-induced alterations of neurotrophin receptor expression on Purkinje cells in the neonatal rat cerebellum

Brain Research, 924(1), 71–81.

By: K. Light*, D. Brown*, B. Newton*, S. Belcher & C. Kane*

author keywords: cerebellum; truncated TrkB; TrkC; ethanol exposure; immunohistochemical
Source: ORCID
Added: March 5, 2021

2002 journal article

Time course and manner of Purkinje neuron death following a single ethanol exposure on postnatal day 4 in the developing rat

Neuroscience, 114(2), 327–337.

By: K. Light*, S. Belcher & D. Pierce*

author keywords: cerebellum; neuronal development; apoptosis; caspase-3; cytochrome c
Source: ORCID
Added: March 5, 2021

2001 journal article

Early postnatal ethanol exposure selectively decreases BDNF and truncated TrkB-T2 receptor mRNA expression in the rat cerebellum

Molecular Brain Research, 93(1), 46–55.

By: K. Light*, Y. Ge* & S. Belcher

author keywords: cerebellum; truncated TrkB; TrkC; ethanol-exposure; RT-PCR; mRNA
Source: ORCID
Added: March 5, 2021

2001 journal article

Estrogen receptor β immunoreactivity in differentiating cells of the developing rat cerebellum

Journal of Comparative Neurology, 430(3), 396–409.

By: R. Jakab*, J. Wong* & S. Belcher

author keywords: differentiation; development; glia; granule cells; growth; immunocytochemistry; migration; neurons; Purkinje cells
Source: ORCID
Added: March 5, 2021

2001 journal article

Estrogenic actions in the brain: Estrogen, phytoestrogens, and rapid intracellular signaling mechanisms

Journal of Pharmacology and Experimental Therapeutics, 299(2), 408–414. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034768705&partnerID=MN8TOARS

By: S. Belcher & A. Zsarnovszky

Source: ORCID
Added: March 5, 2021

2001 journal article

Identification of a developmental gradient of estrogen receptor expression and cellular localization in the developing and adult female rat primary somatosensory cortex

Developmental Brain Research, 129(1), 39–46.

By: A. Zsarnovszky* & S. Belcher

author keywords: barrel; cortex; development; estrogen; estrogen receptor; immunohistochemistry; posteromedial barrel subfield; somatosensory
Source: ORCID
Added: March 5, 2021

2001 journal article

Simplified serum- and steroid-free culture conditions for high-throughput viability analysis of primary cultures of cerebellar granule neurons

Journal of Neuroscience Methods, 110(1-2), 45–55.

By: J. Wong*, P. Kennedy* & S. Belcher

author keywords: cell culture; cerebellum; excitotoxicity; glutamate; LDH release; MK-801; MTT; neuron; neuroprotection; neurotoxicity; reactive oxygen
Source: ORCID
Added: March 5, 2021

1999 journal article

Regulated expression of estrogen receptor α and β mRNA in granule cells during development of the rat cerebellum

Developmental Brain Research, 115(1), 57–69.

By: S. Belcher

author keywords: alternative splicing; cerebellum; estrogen receptor; granule cell; mRNA expression; RT-PCR
Source: ORCID
Added: March 5, 2021

1998 journal article

High-affinity kainate-type ion channels in rat cerebellar granule cells

Journal of Physiology, 510(2), 401–420.

By: K. Pemberton*, S. Belcher, J. Ripellino* & J. Howe*

Source: ORCID
Added: March 5, 2021

1998 journal article

Localization of the m2 muscarinic acetylcholine receptor protein and mRNA in cortical neurons of the normal and cholinergically deafferented rhesus monkey

Journal of Comparative Neurology, 390(1), 112–132.

By: L. Mrzljak*, A. Levey*, S. Belcher & P. Goldman-Rakic*

Source: ORCID
Added: March 5, 2021

1998 journal article

Mutant alleles of the MRS2 gene of yeast nuclear DNA suppress mutations in the catalytic core of a mitochondrial group II intron

Journal of Molecular Biology, 282(3), 525–541.

By: U. Schmidt*, I. Maue*, K. Lehmann*, S. Belcher, U. Stahl* & P. Perlman*

author keywords: group II introns; yeast mitochondria; splicing; MRS2 gene; dominant negative
Source: ORCID
Added: March 5, 2021

1997 journal article

Characterization of RNA editing of the glutamate-receptor subunits GluR5 and GluR6 in granule cells during cerebellar development

Molecular Brain Research, 52(1), 130–138.

By: S. Belcher & J. Howe*

author keywords: glutamate receptor; kainate; RNA editing; cerebellum; granule cell; development
Source: ORCID
Added: March 5, 2021

1996 journal article

A new sodium channel α-subunit gene (Scn9a) from Schwann cells maps to the Scn1a, Scn2a, Scn3a cluster of mouse chromosome 2

Genomics, 36(1), 202–205.

By: M. Beckers*, E. Ernst*, S. Belcher, J. Howe*, R. Levenson* & P. Gros*

Source: ORCID
Added: March 5, 2021

1996 journal article

Cloning of the cDNA encoding the sodium channel β1 subunit from rabbit

Gene, 170(2), 285–286.

By: S. Belcher & J. Howe*

Source: ORCID
Added: March 5, 2021

1996 book

[24] Transformation of Saccharomyces cerevisiae mitochondria using the biolistic gun

In Methods in Enzymology (Vol. 264, pp. 265–278). http://www.scopus.com/inward/record.url?eid=2-s2.0-0029873586&partnerID=MN8TOARS

By: R. Butow, R. Henke, J. Moran, S. Belcher & P. Perlman

Source: ORCID
Added: March 5, 2021

1995 journal article

Cloning of a sodium channel α subunit from rabbit Schwann cells

Proceedings of the National Academy of Sciences of the United States of America, 92(24), 11034–11038.

By: S. Belcher, C. Zerillo*, R. Levenson*, J. Ritchie* & J. Howe*

Source: ORCID
Added: March 5, 2021

1995 journal article

Studies of point mutants define three essential paired nucleotides in the domain 5 substructure of a group II intron

Molecular and Cellular Biology, 15(8), 4479–4488.

By: S. Boulanger*, S. Belcher, U. Schmidt*, S. Dib-Hajj*, T. Schmidt* & P. Perlman*

Source: ORCID
Added: March 5, 2021

1995 journal article

The responsiveness of a tetracycline-sensitive expression system differs in different cell lines

Journal of Biological Chemistry, 270(23), 14168–14174.

By: J. Howe*, B. Skryabin*, S. Belcher, C. Zerillo* & C. Schmauss*

Source: ORCID
Added: March 5, 2021

1994 journal article

Splicing defective mutants of the COXI gene of yeast mitochondrial DNA: Initial definition of the maturase domain of the group II intron AI2

Nucleic Acids Research, 22(11), 2057–2064.

By: J. Moran*, K. Mecklenburg*, P. Sass*, S. Belcher, D. Mahnke*, A. Lewin*, P. Perlman*

Source: ORCID
Added: March 5, 2021

1993 journal article

Mutation of the conserved first nucleotide of a group II intron from yeast mitochondrial DNA reduces the rate but allows accurate splicing

Journal of Biological Chemistry, 268(16), 11929–11938. http://www.scopus.com/inward/record.url?eid=2-s2.0-0027156992&partnerID=MN8TOARS

By: C. Peebles, S. Belcher, M. Zhang, R. Dietrich & P. Perlman

Source: ORCID
Added: March 5, 2021

1992 journal article

A maturase-encoding group MA intron of yeast mitochondria self-splices in vitro

Nucleic Acids Research, 20(7), 1747–1754.

By: S. Hebbar, S. Belcher & P. Perlman*

Source: ORCID
Added: March 5, 2021

Employment

Updated: July 20th, 2019 11:01

2016 - present

North Carolina State University Raleigh, NC, US
Professor Biological Science

Education

Updated: July 20th, 2019 11:05

1990 - 1993

University of Texas Southwestern Department of Biochemistry Dallas, TX, US
PhD Biochemistry