Works (96)

Updated: December 6th, 2023 07:17

2023 journal article

Biodegradable elastomeric circuit boards from citric acid-based polyesters

NPJ FLEXIBLE ELECTRONICS, 7(1).

By: B. Turner n, J. Twiddy n, M. Wilkinsโ€‰ n, S. Ramesh n, K. Kilgour n, E. Domingos n, O. Nasrallah n, S. Menegatti nโ€‰, M. Daniele n

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
Sources: Web Of Science, ORCID
Added: June 19, 2023

2023 article

Breakdown of polyethylene therepthalate microplastics under saltwater conditions using engineered Vibrio natriegens

Li, T., Menegatti, S., & Crook, N. (2023, September 14). AICHE JOURNAL, Vol. 9.

By: T. Li n, S. Menegatti nโ€‰ & N. Crook nโ€‰

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: microplastics; PET biodegradation; surface display; Vibrio natriegens
Sources: Web Of Science, ORCID
Added: September 15, 2023

2023 journal article

Cellulose Acetate-Stabilized Pickering Emulsions: Preparation, Rheology, and Incorporation of Agricultural Active Ingredients

ACS SUSTAINABLE CHEMISTRY & ENGINEERING, 11(42), 15178โ€“15191.

By: M. Sohail n, T. Pirzada nโ€‰, R. Guenther n, E. Barbieri n, T. Sit nโ€‰, S. Menegatti nโ€‰, N. Crook nโ€‰, C. Opperman n, S. Khan nโ€‰

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: nonsporulating microbes; double yielding; Pseudomonas simiae; microstructure; controlledrelease
Sources: Web Of Science, ORCID
Added: October 1, 2023

2023 article

Characterization and implications of host-cell protein aggregates in biopharmaceutical processing

Oh, Y. H., Becker, M. L., Mendola, K. M., Choe, L. H., Min, L., Lee, K. H. H., โ€ฆ Lenhoff, A. M. (2023, January 12). BIOTECHNOLOGY AND BIOENGINEERING, Vol. 1.

By: Y. Oh*, M. Beckerโ€‰*, K. Mendola*, L. Choe*, L. Min*, K. Leeโ€‰*, Y. Yigzaw, A. Seay ...

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: host-cell proteins; monoclonal antibody; protein aggregation; protein purification; size-exclusion chromatography; unfolded protein response
MeSH headings : Cricetinae; Animals; Humans; Cricetulus; Protein Aggregates; Biological Products; Antibodies, Monoclonal; Proteomics / methods; CHO Cells
Sources: Web Of Science, ORCID
Added: February 6, 2023

2023 journal article

Design of 8-mer peptides that block Clostridioides difficile toxin A in intestinal cells

COMMUNICATIONS BIOLOGY, 6(1).

By: S. Sarma n, C. Catella n, E. San Pedro*, X. Xiao n, D. Durmusoglu n, S. Menegatti nโ€‰, N. Crook nโ€‰, S. Magness*, C. Hall nโ€‰

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
Sources: Web Of Science, ORCID
Added: August 27, 2023

2023 journal article

Development of peptide affinity ligands for the purification of polyclonal and monoclonal Fabs from recombinant fluids

JOURNAL OF CHROMATOGRAPHY A, 1687.

By: R. Kilgore n, W. Chu n, D. Bhandari*, D. Fischler*, R. Carbonell n, M. Crapanzano*, S. Menegatti nโ€‰

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: Peptide ligands; Affinity chromatography; Fragment antigen binding; Monoclonal antibodies; Cell culture harvests
MeSH headings : Cricetinae; Animals; Humans; Cricetulus; Ligands; CHO Cells; Molecular Docking Simulation; Protein Binding; Peptides / chemistry; Antibodies, Monoclonal; Chromatography, Affinity
Sources: Web Of Science, ORCID
Added: January 17, 2023

2023 article

Identification and characterization of CHO host-cell proteins in monoclonal antibody bioprocessing

Oh, Y. H., Mendola, K. M., Choe, L. H., Min, L., Lavoie, A. R., Sripada, S. A., โ€ฆ Lenhoff, A. M. (2023, October 25). BIOTECHNOLOGY AND BIOENGINEERING, Vol. 10.

By: Y. Oh*, K. Mendola*, L. Choe*, L. Min*, A. Lavoie n, S. Sripada n, T. Williams nโ€‰, K. Leeโ€‰* ...

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: bioprocessing; Chinese hamster ovary cells; host-cell proteins; monoclonal antibodies; purification
Sources: Web Of Science, ORCID
Added: November 6, 2023

2023 journal article

Integrated in silico and experimental discovery of trimeric peptide ligands targeting Butyrylcholinesterase

COMPUTATIONAL BIOLOGY AND CHEMISTRY, 102.

By: R. Mukherjee n, G. Yow, S. Sarakbi, S. Menegatti nโ€‰, P. V. Gurgel n, R. Carbonell n, B. Bobay*

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: Acetylcholinesterase; Butyrylcholinesterase; Purification; Molecular docking; Affinity ligands
MeSH headings : Butyrylcholinesterase / metabolism; Cholinesterase Inhibitors / chemistry; Ligands; Molecular Docking Simulation; Peptides
Sources: Web Of Science, ORCID
Added: January 17, 2023

2023 article

Molecular Engineering of Cyclic Azobenzene-Peptide Hybrid Ligands for the Purification of Human Blood Factor VIII via Photo-Affinity Chromatography

Prodromou, R., Moore, B. D., Chu, W., Deal, H., San Miguel, A., Brown, A. C., โ€ฆ Menegatti, S. (2023, January 25). ADVANCED FUNCTIONAL MATERIALS, Vol. 1.

By: R. Prodromou n, B. Moore n, W. Chu n, H. Deal n, A. San Miguel nโ€‰, A. Brown n, M. Daniele n, V. Pozdin*, S. Menegatti nโ€‰

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: affinity ligands; azobenzene-peptide hybrids; biomolecular recognition; factor VIII; photo-affinity chromatography
Sources: Web Of Science, ORCID
Added: February 20, 2023

2023 article

One-Step Quantification of anti-Covid-19 Antibodies via Dual Affinity Ratiometric Quenching Assays

Kilgour, K. M., Turner, B. L., Daniele, M., & Menegatti, S. (2023, June 27). ANALYTICAL CHEMISTRY, Vol. 6.

By: K. Kilgour n, B. Turner n, M. Daniele n & S. Menegatti nโ€‰

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
MeSH headings : Animals; Cricetinae; Humans; COVID-19 / diagnosis; SARS-CoV-2; CHO Cells; Cricetulus; Antibodies, Viral
Sources: Web Of Science, ORCID
Added: July 10, 2023

2023 article

Peptide ligands for the affinity purification of adeno-associated viruses from HEK 293 cell lysates

WENNING, C. H. U., Shastry, S., Barbieri, E., Prodromou, R., Greback-Clarke, P., Smith, W., โ€ฆ Menegatti, S. (2023, February 21). (Vol. 2). Vol. 2.

By: C. Wenningโ€‰ n, S. Shastry, E. Barbieriโ€‰ n, R. Prodromou n, P. Greback-Clarke n, W. Smith n, B. Mooreโ€‰ n, R. Kilgoreโ€‰ n ...

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
Source: ORCID
Added: February 22, 2023

2023 article

Peptide ligands for the affinity purification of adeno-associated viruses from HEK 293 cell lysates

Chu, W., Shastry, S., Barbieri, E., Prodromou, R., Greback-Clarke, P., Smith, W., โ€ฆ Menegatti, S. (2023, July 12). BIOTECHNOLOGY AND BIOENGINEERING, Vol. 7.

By: W. Chu n, S. Shastry n, E. Barbieri n, R. Prodromou n, P. Greback-Clarke n, W. Smith n, B. Moore n, R. Kilgore n ...

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: adeno-associated virus; affinity chromatography; HEK 293 lysate; peptide ligands; virus purification
MeSH headings : Humans; Dependovirus / genetics; HEK293 Cells; Ligands; Peptides / genetics; Peptides / metabolism; Amino Acid Sequence; Genetic Vectors
Sources: Web Of Science, ORCID
Added: August 7, 2023

2023 article

Peptonics: A new family of cell-protecting surfactants for the recombinant expression of therapeutic proteins in mammalian cell cultures

Zhang, K., Barbieri, E., Lebarre, J., Rameez, S., Mostafa, S., & Menegatti, S. (2023, October 18). BIOTECHNOLOGY JOURNAL, Vol. 10.

By: K. Zhang n, E. Barbieri n, J. Lebarre n, S. Rameez*, S. Mostafa & S. Menegatti nโ€‰

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: antibodies; mammalian cells; Peptonics; peptoids; Pluronics; surfactants
Sources: Web Of Science, ORCID
Added: November 6, 2023

2023 journal article

Pseudo-affinity capture of K. phaffii host cell proteins in flow-through mode: Purification of protein therapeutics and proteomic study

SEPARATION AND PURIFICATION TECHNOLOGY, 326.

By: S. Sripada n, D. Elhanafi*, L. Collins nโ€‰, T. Williams nโ€‰, M. Linova*, J. Woodleyโ€‰*, C. Boi n, S. Menegatti nโ€‰

co-author countries: Denmark ๐Ÿ‡ฉ๐Ÿ‡ฐ Italy ๐Ÿ‡ฎ๐Ÿ‡น United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: Komagataella phaffii; Chromatography; Protein purification; Monoclonal antibodies; Antibody fragment; Proteomics
Sources: Web Of Science, ORCID
Added: October 23, 2023

2023 journal article

Purification of a monoclonal antibody using a novel high-capacity multimodal cation exchange nonwoven membrane

SEPARATION AND PURIFICATION TECHNOLOGY, 317.

By: J. Fan n, S. Sripada n, D. Pham*, M. Linova*, J. Woodleyโ€‰*, S. Menegatti nโ€‰, C. Boi n, R. Carbonell n

co-author countries: Denmark ๐Ÿ‡ฉ๐Ÿ‡ฐ Italy ๐Ÿ‡ฎ๐Ÿ‡น United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: Salt-tolerant multimodal ligand; Membrane adsorber; Membrane chromatography; Nonwoven membranes; Monoclonal antibodies (mAbs); High-risk HCPs
Sources: Web Of Science, ORCID
Added: June 5, 2023

2023 article

Rational design and experimental evaluation of peptide ligands for the purification of adeno-associated viruses via affinity chromatography

Shastry, S., Chu, W., Barbieri, E., Greback-Clarke, P., Smith, W. K., Cummings, C., โ€ฆ Menegatti, S. (2023, September 28). BIOTECHNOLOGY JOURNAL, Vol. 9.

By: S. Shastry n, W. Chu n, E. Barbieri n, P. Greback-Clarke n, W. Smith n, C. Cummings n, A. Minzoni n, J. Pancorbo n ...

co-author countries: United Kingdom of Great Britain and Northern Ireland ๐Ÿ‡ฌ๐Ÿ‡ง United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: adeno-associated virus; affinity chromatography; gene therapy; peptide ligands; transduction activity
Sources: Web Of Science, ORCID
Added: October 10, 2023

2023 journal article

The downstream bioprocess toolbox for therapeutic viral vectors

JOURNAL OF CHROMATOGRAPHY A, 1709.

By: R. Kilgore n, A. Minzoni n, S. Shastry n, W. Smith n, E. Barbieri n, Y. Wu n, J. Lebarre n, W. Chu n, J. O'Brien n, S. Menegatti nโ€‰

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: Viral vectors; Gene therapy; Affinity ligands; Chromatography; Adsorbents; AAV
Sources: Web Of Science, ORCID
Added: October 30, 2023

2023 article

Toward the quantification of adeno-associated virus titer by electrochemical impedance spectroscopy

2023 IEEE BIOSENSORS CONFERENCE, BIOSENSORS.

By: J. Wang, M. Hosseini, S. Shastry, E. Barbieri, W. Chu, S. Menegattiโ€‰, M. Daniele

author keywords: adeno-associated virus; AAV2; immunosensor; electrochemical impedance spectroscopy; viral vector
Sources: Web Of Science, ORCID
Added: December 4, 2023

2023 article

Towards electrochemical control of pH for regeneration of biosensors

2023 IEEE BIOSENSORS CONFERENCE, BIOSENSORS.

By: C. Sharkey, J. Twiddy, K. Peterson, A. Aroche, S. Menegattiโ€‰ & M. Daniele

author keywords: palladium; regeneration; affinity; pH; immunosensor
Sources: Web Of Science, ORCID
Added: December 4, 2023

2023 article

Vapor phase synthesis of metal-organic frameworks on a nanofibrous aerogel creates enhanced functionality

Rahmanian, V., Ebrahim, M. Z. A., Razavi, S., Abdelmigeed, M., Barbieri, E., Menegatti, S., โ€ฆ Khan, S. A. (2023, November 6). JOURNAL OF MATERIALS CHEMISTRY A, Vol. 11.

By: V. Rahmanian n, M. Ebrahim n, S. Razavi n, M. Abdelmigeed n, E. Barbieri n, S. Menegatti nโ€‰, G. Parsons nโ€‰, F. Li nโ€‰, T. Pirzada nโ€‰, S. Khan nโ€‰

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
Sources: Web Of Science, ORCID
Added: November 11, 2023

2022 journal article

De novo discovery of peptide-based affinity ligands for the fab fragment of human immunoglobulin G

JOURNAL OF CHROMATOGRAPHY A, 1669.

By: X. Xiao n, R. Kilgore n, S. Sarma n, W. Chu n, S. Menegatti nโ€‰ & C. Hall nโ€‰

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: Affinity ligands; Ligand design; Biorecognition; Protein chromatography; Fragment antigen binding
MeSH headings : Humans; Immunoglobulin Fab Fragments / chemistry; Immunoglobulin G; Ligands; Peptides; Tissue Distribution
Sources: Web Of Science, ORCID
Added: May 2, 2022

2022 journal article

An accelerated antibody aggregation test based on time sequenced dynamic light scattering

COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS, 653.

By: C. Conner n, J. McAndrew*, S. Menegatti nโ€‰ & O. Velev nโ€‰

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: Protein colloidal stability; Protein aggregation; Dynamic light scattering; Antibodies
Sources: Web Of Science, ORCID
Added: November 21, 2022

2022 journal article

Development of peptide ligands for the purification of a-1 antitrypsin from cell culture fluids

JOURNAL OF CHROMATOGRAPHY A, 1679.

By: W. Chu n, R. Prodromou n, B. Moore n, D. Elhanafi n, R. Kilgore n, S. Shastry n, S. Menegatti nโ€‰

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: a-1 antitrypsin; Peptide ligands; Affinity chromatography; Protein purification; CHO cell culture harvest
MeSH headings : Animals; CHO Cells; Cell Culture Techniques; Chromatography, Affinity; Cricetinae; Cricetulus; Ligands; Molecular Docking Simulation; Peptides; alpha 1-Antitrypsin
Sources: Web Of Science, ORCID
Added: October 11, 2022

2022 article

Nonwoven Membranes with Infrared Light-Controlled Permeability

Ramesh, S., Davis, J., Roros, A., Zhou, C., He, N., Gao, W., โ€ฆ Genzer, J. (2022, September 9). ACS APPLIED MATERIALS & INTERFACES, Vol. 9.

By: S. Ramesh n, J. Davisโ€‰ n, A. Roros n, C. Zhou n, N. He n, W. Gao n, S. Menegatti nโ€‰, S. Khan nโ€‰, J. Genzer nโ€‰

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: smart-gated membranes; photothermal effect; stimuli-responsive hydrogels; nonwovens; graphene oxide
MeSH headings : Gels; Graphite; Microgels; Permeability; Polypropylenes; Temperature
Sources: Web Of Science, ORCID
Added: November 7, 2022

2022 article

Potent Antibacterial Composite Nonwovens Functionalized with Bioactive Peptides and Polymers

Barbieri, E., Cutright, C. C., Ramesh, S., Khan, S. A., Efimenko, K., Genzer, J., & Menegatti, S. (2022, August 23). ADVANCED MATERIALS INTERFACES, Vol. 8.

By: E. Barbieri n, C. Cutright n, S. Ramesh n, S. Khan nโ€‰, K. Efimenko nโ€‰, J. Genzer nโ€‰, S. Menegatti nโ€‰

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: antimicrobial coating; bacitracin; controlled release; E; coli; polymyxin B; S; aureus; surface functionalization
Sources: Web Of Science, ORCID
Added: August 24, 2022

2022 journal article

Purification of Adeno-Associated Virus (AAV) Serotype 2 from Spodoptera frugiperda (Sf9) Lysate by Chromatographic Nonwoven Membranes

MEMBRANES, 12(10).

By: J. Fan n, E. Barbieri n, S. Shastry n, S. Menegatti nโ€‰, C. Boi & R. Carbonell n

co-author countries: Italy ๐Ÿ‡ฎ๐Ÿ‡น United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: adeno-associated virus (AAV); viral vector purification; nonwovens; membrane adsorber; anion exchange; cation exchange; membrane chromatography
Sources: Web Of Science, ORCID
Added: November 14, 2022

2022 review

Self-healing and repair of fabrics: A comprehensive review of the application toolkit

[Review of ]. MATERIALS TODAY, 54, 90โ€“109.

By: S. Ramesh n, S. Khan nโ€‰, Y. Park*, E. Ford n, S. Menegatti nโ€‰ & J. Genzer nโ€‰

co-author countries: Korea (Republic of) ๐Ÿ‡ฐ๐Ÿ‡ท United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: Self-repair; Self-healing; Fabrics; Nonwovens; Property recovery; Repair
Sources: Web Of Science, ORCID
Added: August 15, 2022

2022 article

Toward an Aptasensor for Monitoring of Tacrolimus

2022 IEEE SENSORS.

By: B. Lee n, A. Aroche n, S. Menegatti nโ€‰ & M. Daniele n

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: aptamer; tacrolimus; surface plasmon resonance; square wave voltammetry
Sources: Web Of Science, ORCID
Added: February 27, 2023

2022 article

Towards continuous mAb purification: Clearance of host cell proteins from CHO cell culture harvests via "flow-through affinity chromatography" using peptide-based adsorbents

Sripada, S. A., Chu, W., Williams, T. I., Teten, M. A., Mosley, B. J., Carbonell, R. G., โ€ฆ Menegatti, S. (2022, April 22). BIOTECHNOLOGY AND BIOENGINEERING, Vol. 4.

By: S. Sripada n, W. Chu n, T. Williams nโ€‰, M. Teten n, B. Mosley n, R. Carbonell n, A. Lenhoffโ€‰*, S. Cramerโ€‰* ...

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ

Contributors: S. Sripada n, W. Chu n, T. Williams nโ€‰, M. Teten n, B. Mosley n, R. Carbonell n, A. Lenhoffโ€‰*, S. Cramerโ€‰* ...

author keywords: CHO; flow-through chromatography; host cell proteins; monoclonal antibodies; peptide-based adsorbents
MeSH headings : Animals; Antibodies, Monoclonal / chemistry; CHO Cells; Cell Culture Techniques; Chromatography, Affinity / methods; Cricetinae; Cricetulus; Peptides / chemistry; Proteomics / methods
Sources: Web Of Science, ORCID
Added: April 10, 2022

2021 journal article

Design and in situ biosynthesis of precision therapies against gastrointestinal pathogens

CURRENT OPINION IN PHYSIOLOGY, 23.

By: D. Durmusoglu n, C. Catella n, E. Purnell n, S. Menegatti nโ€‰ & N. Crook nโ€‰

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
Sources: Web Of Science, ORCID
Added: October 26, 2021

2021 article

Development of Peptide Ligands for Targeted Capture of Host Cell Proteins from Cell Culture Production Harvests

PROTEOMIC PROFILING, 2 EDITION, Vol. 2261, pp. 489โ€“506.

By: R. Lavoie n, T. Islamโ€‰ n, W. Blackburn*, R. Carbonell n & S. Menegatti nโ€‰

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ

Contributors: R. Lavoie n, T. Williams nโ€‰, R. Blackburn*, R. Carbonell n & S. Menegatti nโ€‰

author keywords: Proteomics; Mass spectrometry; Host cell proteins; Monoclonal antibodies; Peptide ligands; Flow-through chromatography
MeSH headings : Animals; CHO Cells; Cricetulus; Enzyme-Linked Immunosorbent Assay; Humans; Ligands; Microscopy, Fluorescence; Peptide Library; Peptides / metabolism; Protein Binding; Proteins / isolation & purification; Proteins / metabolism; Proteomics; Solid Phase Extraction; Tandem Mass Spectrometry
Sources: Web Of Science, ORCID
Added: April 8, 2021

2021 journal article

Dual-Responsive Microgels for Structural Repair and Recovery of Nonwoven Membranes for Liquid Filtration

ACS APPLIED POLYMER MATERIALS, 3(3), 1508โ€“1517.

By: S. Ramesh n, J. Davis n, A. Roros n, J. Eiben n, T. Fabiani n, R. Smith n, L. Reynolds n, B. Pourdeyhimi nโ€‰ ...

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: stimuli-responsive; microgels; nonwovens; permeability; healing; fabric repair
Sources: Web Of Science, ORCID
Added: February 13, 2021

2021 journal article

Engineering Next Generation Cyclized Peptide Ligands for Light-Controlled Capture and Release of Therapeutic Proteins

ADVANCED FUNCTIONAL MATERIALS, 31(27).

By: R. Prodromou n, K. Day n, S. Saberi-Bosari n, J. Schneible n, M. Mabeโ€‰ n, A. San Miguel nโ€‰, M. Daniele n, V. Pozdin*, S. Menegatti nโ€‰

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: azobenzene; cyclized peptide; light‐ controlled biorecognition; microfluidic devices; photochromic switch; photo‐ isomerization kinetics
Sources: Web Of Science, ORCID
Added: May 24, 2021

2021 article

In Silico Identification and Experimental Validation of Peptide-Based Inhibitors Targeting Clostridium difficile Toxin A

Xiao, X., Sarma, S., Menegatti, S., Crook, N., Magness, S. T., & Hall, C. K. (2021, December 29). ACS CHEMICAL BIOLOGY, Vol. 12.

By: X. Xiao n, S. Sarma n, S. Menegatti nโ€‰, N. Crook nโ€‰, S. Magness* & C. Hall nโ€‰

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
MeSH headings : Bacterial Toxins / antagonists & inhibitors; Bacterial Toxins / chemistry; Computer Simulation; Drug Design; Enterotoxins / antagonists & inhibitors; Enterotoxins / chemistry; Models, Molecular; Peptides / chemistry; Peptides / pharmacology; Protein Binding; Protein Conformation; Protein Domains; Reproducibility of Results
Sources: Web Of Science, ORCID
Added: December 30, 2021

2021 journal article

Peptides and pseudopeptide ligands: a powerful toolbox for the affinity purification of current and next-generation biotherapeutics

JOURNAL OF CHROMATOGRAPHY A, 1635.

By: W. Chu n, R. Prodromou n, K. Day n, J. Schneible n, K. Bacon n, J. Bowen n, R. Kilgore n, C. Catella n ...

co-author countries: China ๐Ÿ‡จ๐Ÿ‡ณ United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: Affinity ligands; peptides; peptoids; pseudopeptides; biotherapeutics
MeSH headings : Antibodies / isolation & purification; Biological Products / isolation & purification; Chemistry, Pharmaceutical / methods; Chromatography, Affinity; Family Characteristics; Humans; Ligands; Peptides / isolation & purification; Peptoids / chemistry; Proteins / isolation & purification
Sources: Web Of Science, ORCID
Added: January 25, 2021

2021 article

Purification of polyclonal immunoglobulin G from human serum using peptide-based adsorbents

Chu, W., Sripada, S. A., Reese, H. R., Bhandari, D., Adams, A., Sly, J., โ€ฆ Menegatti, S. (2021, October 20). AICHE JOURNAL, Vol. 10.

By: W. Chu n, S. Sripada n, H. Reese n, D. Bhandari, A. Adams n, J. Sly, M. Crapanzano, S. Menegatti nโ€‰

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: affinity ligands; LigaGuard (TM); LigaTrap (TM); polyclonal antibodies; protein chromatography
Sources: Web Of Science, ORCID
Added: November 1, 2021

2021 journal article

Quantitative Yeast-Yeast Two Hybrid for the Discovery and Binding Affinity Estimation of Protein-Protein Interactions

ACS SYNTHETIC BIOLOGY, 10(3), 505โ€“514.

By: K. Bacon n, A. Blain n, J. Bowen n, M. Burroughs n, N. McArthurโ€‰ n, S. Menegatti nโ€‰, B. Rao n

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: yeast two-hybrid; protein-protein interactions; protein engineering; yeast surface display; post-translational modification; cDNA library
MeSH headings : Gene Library; Genes, Reporter; Protein Binding; Protein Domains; Protein Interaction Maps; Saccharomyces cerevisiae / genetics; Saccharomyces cerevisiae / metabolism; Smad3 Protein / chemistry; Smad3 Protein / metabolism; Transcription Factors / chemistry; Transcription Factors / metabolism; Two-Hybrid System Techniques
Sources: Web Of Science, ORCID
Added: March 29, 2021

2021 journal article

Removal of host cell proteins from cell culture fluids by weak partitioning chromatography using peptide-based adsorbents

SEPARATION AND PURIFICATION TECHNOLOGY, 257.

By: R. Lavoie n, W. Chu n, J. Lavoie n, Z. Hetzler n, T. Williams nโ€‰, R. Carbonell n, S. Menegatti nโ€‰

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ

Contributors: R. Lavoie n, W. Chu n, J. Lavoie n, Z. Hetzler n, T. Williams nโ€‰, R. Carbonell n, S. Menegatti nโ€‰

author keywords: Host cell proteins; Monoclonal antibodies; Flow-through chromatography; Weak partitioning mode; Polishing; Proteomics; Peptide ligands
Sources: Web Of Science, ORCID
Added: January 11, 2021

2021 article

Resorbable elastomers for implantable medical devices: highlights and applications

Turner, B., Ramesh, S., Menegatti, S., & Daniele, M. (2021, December 29). POLYMER INTERNATIONAL, Vol. 12.

By: B. Turner n, S. Ramesh n, S. Menegatti nโ€‰ & M. Daniele n

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: elastomers; implantable medical devices; resorbable; bioelectronics
Sources: Web Of Science, ORCID
Added: January 10, 2022

2021 journal article

Screening of Yeast Display Libraries of Enzymatically Treated Peptides to Discover Macrocyclic Peptide Ligands

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 22(4).

By: J. Bowen n, J. Schneible n, K. Bacon n, C. Labar n, S. Menegatti nโ€‰ & B. Rao n

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: yeast display library; cyclic peptide; Yes Associated Protein (YAP) 65; WW domain; transglutaminase
MeSH headings : Adaptor Proteins, Signal Transducing / chemistry; Adaptor Proteins, Signal Transducing / metabolism; Albumins / metabolism; Binding Sites; Combinatorial Chemistry Techniques; Endoplasmic Reticulum / metabolism; Flow Cytometry; Ligands; Muramidase / metabolism; Peptides, Cyclic / isolation & purification; Peptides, Cyclic / pharmacology; Protein Binding; Protein Engineering / methods; Transcription Factors / chemistry; Transcription Factors / metabolism; Transglutaminases / metabolism; YAP-Signaling Proteins; Yeasts / genetics; Yeasts / growth & development
Sources: Web Of Science, ORCID
Added: March 22, 2021

2021 article

Surface-Bound Microgels for Separation, Sensing, and Biomedical Applications

Cutright, C. C., Harris, J. L., Ramesh, S., Khan, S. A., Genzer, J., & Menegatti, S. (2021, August 16). ADVANCED FUNCTIONAL MATERIALS, Vol. 8.

By: C. Cutright n, J. Harris n, S. Ramesh n, S. Khan nโ€‰, J. Genzer nโ€‰ & S. Menegatti nโ€‰

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: deposition techniques; hydrogel microparticles; stimuli-responsive polymers; surface coating; surface morphology
Sources: Web Of Science, ORCID
Added: August 17, 2021

2021 journal article

Synthetic Platelet Microgels Containing Fibrin Knob B Mimetic Motifs Enhance Clotting Responses

ADVANCED THERAPEUTICS, 4(5).

By: S. Nandi n, E. Mihalko n, K. Nellenbach n, M. Castanedaโ€‰ n, J. Schneible n, M. Harp*, H. Deal n, M. Daniele n ...

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: bleeding; Clotting; fibrin; hemostasis; microgel
Sources: Web Of Science, ORCID
Added: April 5, 2021

2021 article

Ultrasound-Powered Implants: A Critical Review of Piezoelectric Material Selection and Applications

Turner, B. L., Senevirathne, S., Kilgour, K., McArt, D., Biggs, M., Menegatti, S., & Daniele, M. A. (2021, July 8). ADVANCED HEALTHCARE MATERIALS, Vol. 7.

By: B. Turner n, S. Senevirathne*, K. Kilgour n, D. McArtโ€‰*, M. Biggsโ€‰*, S. Menegatti nโ€‰, M. Daniele n

co-author countries: United Kingdom of Great Britain and Northern Ireland ๐Ÿ‡ฌ๐Ÿ‡ง Ireland ๐Ÿ‡ฎ๐Ÿ‡ช United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: energy harvesting; implantable medical devices; piezoelectric devices; ultrasound; wireless power transfer
MeSH headings : Electric Power Supplies; Movement; Prostheses and Implants; Ultrasonography
Sources: Web Of Science, ORCID
Added: July 19, 2021

2020 journal article

A multiscale coarse-grained model to predict the molecular architecture and drug transport properties of modified chitosan hydrogels

SOFT MATTER, 16(47).

By: A. Singhalโ€‰*, J. Schneible n, R. Lilova n, C. Hall nโ€‰, S. Menegatti nโ€‰ & A. Grafmueller

co-author countries: Germany ๐Ÿ‡ฉ๐Ÿ‡ช United States of America ๐Ÿ‡บ๐Ÿ‡ธ
MeSH headings : Chitosan; Doxorubicin; Drug Liberation; Hydrogels; Polymers
Sources: Web Of Science, ORCID
Added: January 4, 2021

2020 journal article

Affibody-Binding Ligands

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 21(11).

By: A. Barozzi n, R. Lavoie n, K. Day n, R. Prodromou n & S. Menegatti nโ€‰

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: affibody; peptide ligands; affinity chromatography; biomanufacturing; protein purification
MeSH headings : Amino Acid Sequence; Humans; Immunoglobulin G / metabolism; Ligands; Molecular Docking Simulation; Peptide Library; Peptides / chemistry; Peptides / metabolism; Recombinant Fusion Proteins / metabolism; Serum Albumin, Human / metabolism; Temperature
Sources: Web Of Science, ORCID
Added: July 20, 2020

2020 journal article

Chitosan Hydrogels for Synergistic Delivery of Chemotherapeutics to Triple Negative Breast Cancer Cells and Spheroids

PHARMACEUTICAL RESEARCH, 37(7).

By: J. Schneible n, A. Young n, M. Daniele n & S. Menegatti nโ€‰

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
MeSH headings : Acetylation; Antineoplastic Combined Chemotherapy Protocols / administration & dosage; Antineoplastic Combined Chemotherapy Protocols / chemistry; Antineoplastic Combined Chemotherapy Protocols / pharmacology; Cell Line, Tumor; Cell Survival / drug effects; Chitosan / chemistry; Deoxycytidine / administration & dosage; Deoxycytidine / analogs & derivatives; Deoxycytidine / chemistry; Deoxycytidine / pharmacology; Doxorubicin / administration & dosage; Doxorubicin / chemistry; Doxorubicin / pharmacology; Drug Carriers; Drug Compounding; Drug Liberation; Drug Synergism; Female; Humans; Hydrogels; Kinetics; Spheroids, Cellular; Triple Negative Breast Neoplasms / drug therapy; Triple Negative Breast Neoplasms / pathology; Gemcitabine
Sources: Web Of Science, ORCID
Added: August 10, 2020

2020 journal article

Chromatographic assay to probe the binding energy and mechanisms of homologous proteins to surface-bound ligands

JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 1136.

By: H. Reese n, C. Shanahan n, J. Lembo n, L. Tsonev, A. Hirsh & S. Menegatti nโ€‰

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: Peptide ligands; IgG subclasses; pISep dual pH and salt LC gradients; Isothermal titration calorimetry; In silico docking, IgG peptide interaction forces
MeSH headings : Adsorption; Calorimetry; Chromatography, Affinity / methods; Humans; Hydrogen-Ion Concentration; Immunoglobulin G / chemistry; Immunoglobulin G / isolation & purification; Immunoglobulin G / metabolism; Ligands; Molecular Dynamics Simulation; Peptides / chemistry; Peptides / metabolism; Protein Binding; Recombinant Proteins / chemistry; Recombinant Proteins / isolation & purification; Recombinant Proteins / metabolism; Sodium Chloride / chemistry; Static Electricity
Sources: Web Of Science, ORCID
Added: February 17, 2020

2020 journal article

Discovery of Membrane-Permeating Cyclic Peptides via mRNA Display

BIOCONJUGATE CHEMISTRY, 31(10), 2325โ€“2338.

By: J. Bowen n, A. Schloop n, G. Reeves*, S. Menegatti nโ€‰ & B. Rao n

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
MeSH headings : Animals; Cell Line; Cell-Penetrating Peptides / chemistry; Cell-Penetrating Peptides / genetics; Cell-Penetrating Peptides / pharmacokinetics; Drosophila melanogaster / embryology; Gene Library; Humans; Mice; Models, Molecular; NIH 3T3 Cells; Peptides, Cyclic / chemistry; Peptides, Cyclic / genetics; Peptides, Cyclic / pharmacokinetics; Permeability; RNA, Messenger / genetics
Sources: Web Of Science, ORCID
Added: December 21, 2020

2020 journal article

Dual-Affinity Ratiometric Quenching (DARQ) Assay for the Quantification of Therapeutic Antibodies in CHO-S Cell Culture Fluids

ANALYTICAL CHEMISTRY, 92(24), 16274โ€“16283.

By: B. Turner n, K. Kilgour n, S. Stine n, M. Daniele n & S. Menegatti nโ€‰

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
MeSH headings : Animals; Antibodies, Monoclonal / analysis; Antibodies, Monoclonal / immunology; Antibodies, Monoclonal / therapeutic use; Antigens / immunology; CHO Cells; Cricetulus; Spectrometry, Fluorescence / methods
Sources: Web Of Science, ORCID
Added: January 11, 2021

2020 journal article

Exploring the physicochemical and morphological properties of peptideโ€hybridized dendrimers ( DendriPeps ) and their aggregates

Journal of Polymer Science, 58(16), 2234โ€“2247.

By: R. Smith n, T. Fabiani n, S. Wang n, S. Ramesh n, S. Khan nโ€‰, E. Santiso nโ€‰, F. Silvaโ€‰*, C. Gorman nโ€‰, S. Menegatti nโ€‰

co-author countries: Brazil ๐Ÿ‡ง๐Ÿ‡ท United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: dendrimets; DendriPeps; molecular dynamics; PAMAM; reversible aggregation
Sources: Web Of Science, ORCID, Crossref
Added: July 27, 2020

2020 journal article

Highly Efficient 1-Octene Hydroformylation at Low Syngas Pressure: From Single-Droplet Screening to Continuous Flow Synthesis

ACS CATALYSIS, 10(14), 7535โ€“7542.

By: K. Raghuvanshi n, C. Zhu n, M. Ramezani n, S. Menegatti nโ€‰, E. Santiso nโ€‰, D. Mason*, J. Rodgers*, M. Janka*, M. Abolhasani nโ€‰

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: hydroformylation; flow chemistry; BISBI; continuous organic synthesis; membrane flow reactor
Sources: Web Of Science, ORCID
Added: August 17, 2020

2020 journal article

Isolation of Chemically Cyclized Peptide Binders Using Yeast Surface Display

ACS COMBINATORIAL SCIENCE, 22(10), 519โ€“532.

By: K. Bacon n, A. Blain n, M. Burroughs n, N. McArthrur n, B. Rao n & S. Menegatti nโ€‰

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: cyclic peptides; interleukin-17 (IL-17); library screening; yeast-display libraries; affinity ligands
MeSH headings : Biophysical Phenomena; Cell Membrane / chemistry; Cyclization; Flow Cytometry; Humans; Interleukin-17 / chemistry; Molecular Docking Simulation; Peptide Library; Peptides, Cyclic / isolation & purification; Protein Binding; Protein Conformation; Protein Engineering; Recombinant Proteins / chemistry; Saccharomyces cerevisiae / chemistry; Saccharomyces cerevisiae / ultrastructure; Structure-Activity Relationship; Surface Properties
Sources: Web Of Science, ORCID
Added: November 9, 2020

2020 journal article

Modified gaphene oxide (GO) particles in peptide hydrogels: a hybrid system enabling scheduled delivery of synergistic combinations of chemotherapeutics

JOURNAL OF MATERIALS CHEMISTRY B, 8(17), 3852โ€“3868.

By: J. Schneible n, K. Shi n, A. Young n, S. Ramesh n, N. He*, C. Dowdey n, J. Dubnansky n, R. Libya ...

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
MeSH headings : Antibiotics, Antineoplastic / chemistry; Antibiotics, Antineoplastic / pharmacology; Cell Proliferation / drug effects; Cell Survival / drug effects; Doxorubicin / chemistry; Doxorubicin / pharmacology; Drug Delivery Systems; Drug Screening Assays, Antitumor; Graphite / chemistry; Humans; Hydrogels / chemistry; Molecular Dynamics Simulation; Particle Size; Peptides / chemistry; Surface Properties; Tumor Cells, Cultured
Sources: Web Of Science, ORCID
Added: June 1, 2020

2020 journal article

Nonwoven fiber mats with thermo-responsive permeability to inorganic and organic electrolytes

JOURNAL OF MEMBRANE SCIENCE, 616.

By: C. Cutright n, R. Finkelstein n, E. Orlowski n, E. McIntosh n, Z. Brotherton n, T. Fabiani n, S. Khan nโ€‰, J. Genzer nโ€‰, S. Menegatti nโ€‰

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: Stimuli-responsive hydrogels; "Smart gating" membranes; Stimuli-controlled permeability; Fiber coating; Controlled transport
Sources: Web Of Science, ORCID
Added: October 12, 2020

2020 journal article

Novel peptide ligands for antibody purification provide superior clearance of host cell protein impurities

JOURNAL OF CHROMATOGRAPHY A, 1625.

By: H. Reese n, X. Xiao n, C. Shanahan n, G. Driesscheโ€‰ n, D. Fourches n, R. Carbonell n, C. Hall nโ€‰, S. Menegatti nโ€‰

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: Peptide affinity ligands; Protein A; mAb purification; Affinity chromatography; Peptide design
MeSH headings : Amino Acid Sequence; Animals; Antibodies, Monoclonal / isolation & purification; Antibodies, Monoclonal / metabolism; CHO Cells; Chromatography, Affinity / methods; Cricetinae; Cricetulus; Immunoglobulin G / isolation & purification; Immunoglobulin G / metabolism; Ligands; Peptides / chemical synthesis; Peptides / chemistry; Peptides / metabolism; Protein Binding; Staphylococcal Protein A / chemistry; Staphylococcal Protein A / metabolism
Sources: Web Of Science, ORCID
Added: August 10, 2020

2020 journal article

Novel peptoid-based adsorbents for purifying IgM and IgG from polyclonal and recombinant sources

JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 1137.

By: H. Reese n, T. Bordelon, C. Shanahan n, M. Crapanzano, J. Sly & S. Menegatti nโ€‰

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: Peptoid ligand; Affinity purification; Protein chromatography; IgG and IgM; Antibody therapeutics
MeSH headings : Animals; CHO Cells; Chromatography, Affinity / methods; Cricetinae; Cricetulus; HEK293 Cells; Humans; Immunoglobulin G / isolation & purification; Immunoglobulin G / metabolism; Immunoglobulin M / isolation & purification; Immunoglobulin M / metabolism; Peptoids / chemistry; Peptoids / metabolism; Recombinant Proteins / isolation & purification; Recombinant Proteins / metabolism
Sources: Web Of Science, ORCID
Added: February 10, 2020

2020 journal article

Packing density, homogeneity, and regularity: Quantitative correlations between topology and thermoresponsive morphology of PNIPAM-co-PAA microgel coatings

APPLIED SURFACE SCIENCE, 508.

By: C. Cutright n, Z. Brotherton n, L. Alexander n, J. Harris n, K. Shi n, S. Khan nโ€‰, J. Genzer nโ€‰, S. Menegatti nโ€‰

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: Stimuli-responsive microgels; Self-assembled monolayers; Spin coating; Particle interactions; Particle packing
Sources: Web Of Science, ORCID
Added: April 14, 2020

2020 review

Past, Present, and Future of Affinity-based Cell Separation Technologies

[Review of ]. ACTA BIOMATERIALIA, 112, 29โ€“51.

By: K. Bacon n, A. Lavoie n, B. Rao n, M. Daniele n & S. Menegatti nโ€‰

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: Cell purification; Immunoaffinity; MACS; FACS; Microfluidics
MeSH headings : Cell Separation; Chromatography, Affinity; Flow Cytometry; Ligands; Regenerative Medicine
Sources: Web Of Science, ORCID
Added: August 3, 2020

2020 review

Peptide science: A "rule model" for new generations of peptidomimetics

[Review of ]. ACTA BIOMATERIALIA, 102, 35โ€“74.

By: H. Reese n, C. Shanahan n, C. Proulx nโ€‰ & S. Menegatti nโ€‰

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: Peptides; Peptoids; Simulation; Peptidomimetics; Biomaterials
MeSH headings : Amino Acid Sequence; Molecular Dynamics Simulation; Peptidomimetics / chemistry; Peptoids / chemistry; Protein Structure, Secondary; Protein Structure, Tertiary; Sequence Analysis, Protein
Sources: Web Of Science, ORCID
Added: February 27, 2020

2020 journal article

Photoinduced reconfiguration to control the protein-binding affinity of azobenzene-cyclized peptides

JOURNAL OF MATERIALS CHEMISTRY B, 8(33), 7413โ€“7427.

By: K. Day n, J. Schneible n, A. Young n, V. Pozdin*, G. Driesscheโ€‰ n, L. Gaffney n, R. Prodromou n, D. Freytes n ...

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
MeSH headings : Amino Acid Sequence; Azo Compounds / chemistry; Hydrogen-Ion Concentration; Isomerism; Osmolar Concentration; Peptides, Cyclic / chemistry; Photochemical Processes
Sources: Web Of Science, ORCID
Added: September 14, 2020

2020 journal article

Platelet-rich plasma lysate displays antibiofilm properties and restores antimicrobial activity against synovial fluid biofilms in vitro

JOURNAL OF ORTHOPAEDIC RESEARCH, 38(6), 1365โ€“1374.

By: J. Gilbertie n, T. Schaerโ€‰*, A. Schubert n, M. Jacob n, S. Menegatti nโ€‰, R. Lavoie n, L. Schnabel n

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: biofilms; equine model; infectious arthritis; platelet-rich plasma; Staphylococcus aureus
MeSH headings : Aminoglycosides / pharmacology; Animals; Anti-Bacterial Agents / pharmacology; Arthritis, Infectious / drug therapy; Biofilms / drug effects; Female; Horses; Male; Molecular Weight; Platelet-Rich Plasma; Synovial Fluid / microbiology
Sources: Web Of Science, ORCID
Added: January 27, 2020

2020 article

Purification of animal immunoglobulin G (IgG) using peptoid affinity ligands

BIOTECHNOLOGY PROGRESS.

By: H. Reese n, T. Bordelon, F. Odeh, A. Broussard, C. Kormos, A. Murphy, C. Shanahan n, S. Menegatti nโ€‰

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
MeSH headings : Animals; Chickens; Chromatography, Affinity; Goats; Immunoglobulin G / chemistry; Immunoglobulin G / immunology; Immunoglobulin G / isolation & purification; Immunoglobulins / chemistry; Immunoglobulins / isolation & purification; Ligands; Mice; Peptoids / chemistry; Protein Binding / drug effects; Rabbits; Sheep
Sources: Web Of Science, ORCID
Added: August 31, 2020

2020 journal article

Targeted capture of Chinese hamster ovary host cell proteins: Peptide ligand binding by proteomic analysis

BIOTECHNOLOGY AND BIOENGINEERING, 117(2), 438โ€“452.

By: R. Lavoie n, A. Fazio n, T. Williams nโ€‰, R. Carbonell n & S. Menegatti nโ€‰

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ

Contributors: R. Lavoie n, A. Fazio n, T. Williams nโ€‰, R. Carbonell n & S. Menegatti nโ€‰

author keywords: host cell proteins; monoclonal antibodies; polishing; peptide ligands; protein purification
MeSH headings : Animals; Antibodies, Monoclonal / isolation & purification; CHO Cells; Cricetinae; Cricetulus; Ligands; Peptides / chemistry; Peptides / metabolism; Protein Binding; Proteins / analysis; Proteins / chemistry; Proteins / isolation & purification; Proteins / metabolism; Proteomics / methods; Recombinant Proteins / isolation & purification
Sources: Web Of Science, ORCID
Added: December 2, 2019

2020 journal article

Use of Target-Displaying Magnetized Yeast in Screening mRNA-Display Peptide Libraries to Identify Ligands

ACS COMBINATORIAL SCIENCE, 22(12), 738โ€“744.

By: K. Bacon n, J. Bowen n, H. Reese n, B. Rao n & S. Menegatti nโ€‰

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: yeast surface display; yeast magnetization; peptide ligands; mRNA-display library; ligand discovery
MeSH headings : Ligands; Mitochondrial Membrane Transport Proteins / chemistry; Models, Molecular; Peptide Library; RNA, Messenger / chemistry; Saccharomyces cerevisiae / chemistry; Saccharomyces cerevisiae Proteins / chemistry; Transcription Factors / chemistry
Sources: Web Of Science, ORCID
Added: January 11, 2021

2019 journal article

Affordable Microfluidic Bead-Sorting Platform for Automated Selection of Porous Particles Functionalized with Bioactive Compounds

SCIENTIFIC REPORTS, 9(1).

By: S. Saberi-Bosari n, M. Omaryโ€‰ n, A. Lavoie n, R. Prodromou n, K. Day n, S. Menegatti nโ€‰, A. San-Miguelโ€‰ n

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
MeSH headings : Combinatorial Chemistry Techniques / instrumentation; Humans; Image Processing, Computer-Assisted; Immunoglobulin G / chemistry; Lab-On-A-Chip Devices; Microfluidic Analytical Techniques / instrumentation; Peptide Library; Porosity; Proof of Concept Study; Unsupervised Machine Learning
Sources: Web Of Science, ORCID
Added: May 28, 2019

2019 journal article

DendriPeps: Expanding Dendrimer Functionality by Hybridizing Poly(amidoamine) (PAMAM) Scaffolds with Peptide Segments

MACROMOLECULAR RAPID COMMUNICATIONS, 40(22).

By: R. Smith n, C. Gorman nโ€‰ & S. Menegatti nโ€‰

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: internally functionalized dendrimers; orthogonal protection strategies; poly(amidoamine); polymer-peptide chemistry
MeSH headings : Amino Acids / chemistry; Dendrimers / chemistry; Dendrimers / metabolism; Drug Delivery Systems / methods; Molecular Dynamics Simulation; Molecular Structure; Peptides / chemistry; Peptides / metabolism; Tissue Scaffolds / chemistry
Sources: Web Of Science, ORCID
Added: October 14, 2019

2019 journal article

Discovery and Evaluation of Peptide Ligands for Selective Adsorption and Release of Cas9 Nuclease on Solid Substrates

BIOCONJUGATE CHEMISTRY, 30(12), 3057โ€“3068.

By: K. Day n, R. Prodromou n, S. Bosari n, A. Lavoie n, M. Omaryโ€‰ n, C. Market n, A. San Miguel nโ€‰, S. Menegatti nโ€‰

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
MeSH headings : Adsorption; Amino Acid Sequence; Binding Sites; CRISPR-Associated Protein 9 / isolation & purification; CRISPR-Associated Protein 9 / metabolism; Drug Discovery; Ligands; Molecular Docking Simulation; Peptide Library; Peptides / metabolism; Resins, Synthetic / chemistry; Substrate Specificity
Sources: Web Of Science, ORCID
Added: January 13, 2020

2019 journal article

Multiplexed Competitive Screening of One-Bead-One-Component Combinatorial Libraries Using a ClonePix 2 Colony Sorter

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 20(20).

By: R. Lavoie n, A. Fazio n, R. Carbonell n & S. Menegatti nโ€‰

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: library screening; bioactive peptides; ligand development; affinity chromatography; affinity ligand; ClonePix 2
MeSH headings : Animals; Cell Line; Chromatography, Affinity / methods; Drug Discovery / methods; Humans; Immunoglobulin G; Ligands; Optical Imaging / methods; Peptide Library; Small Molecule Libraries
Sources: Web Of Science, ORCID
Added: December 16, 2019

2019 journal article

Optimization of Sequence, Display, and Mode of Operation of IgG-Binding Peptide Ligands to Develop Robust, High-Capacity Affinity Adsorbents That Afford High IgG Product Quality

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 20(1).

By: T. Islam n, A. Naik n, Y. Hashimotoโ€‰*, S. Menegatti nโ€‰ & R. Carbonell n

co-author countries: Japan ๐Ÿ‡ฏ๐Ÿ‡ต United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: affinity chromatography; peptide ligand; antibody purification; binding capacity; process optimization; aggregate removal
Sources: Web Of Science, ORCID
Added: March 11, 2019

2019 journal article

Screening Yeast Display Libraries against Magnetized Yeast Cell Targets Enables Efficient Isolation of Membrane Protein Binders

ACS COMBINATORIAL SCIENCE, 21(12), 817โ€“832.

By: K. Bacon n, M. Burroughs n, A. Blain n, S. Menegatti nโ€‰ & B. Rao n

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: yeast magnetization; combinatorial library screening; ligand discovery; yeast surface display; membrane protein; Sso7d; nanobody
MeSH headings : Combinatorial Chemistry Techniques; Drug Evaluation, Preclinical; Ferric Compounds / chemistry; Ferric Compounds / pharmacology; Magnetic Phenomena; Mitochondria / drug effects; Mitochondria / metabolism; Mitochondrial Membrane Transport Proteins / antagonists & inhibitors; Mitochondrial Membrane Transport Proteins / isolation & purification; Mitochondrial Membrane Transport Proteins / metabolism; Nanoparticles / chemistry; Protein Binding / drug effects; Saccharomyces cerevisiae / cytology; Saccharomyces cerevisiae / drug effects; Saccharomyces cerevisiae / metabolism; Saccharomyces cerevisiae Proteins / antagonists & inhibitors; Saccharomyces cerevisiae Proteins / isolation & purification; Saccharomyces cerevisiae Proteins / metabolism; Small Molecule Libraries / chemistry; Small Molecule Libraries / pharmacology
Sources: Web Of Science, ORCID
Added: December 30, 2019

2019 journal article

Silica resins and peptide ligands to develop disposable affinity adsorbents for antibody purification

BIOCHEMICAL ENGINEERING JOURNAL, 145, 53โ€“61.

By: A. Naika, T. Islam n, T. Terasaka*, Y. Oharaโ€‰*, Y. Hashimotoโ€‰*, S. Menegatti nโ€‰, R. Carbonell n

co-author countries: Japan ๐Ÿ‡ฏ๐Ÿ‡ต United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: Silica resins; Peptide ligands; Monoclonal antibodies; Llama antibodies; Rabbit antibodies
Sources: Web Of Science, ORCID
Added: May 13, 2019

2019 journal article

Tailoring the Chemical Modification of Chitosan Hydrogels to Fine-Tune the Release of a Synergistic Combination of Chemotherapeutics

BIOMACROMOLECULES, 20(8), 3126โ€“3141.

By: J. Schneible n, A. Singhalโ€‰*, R. Lilova n, C. Hall nโ€‰, A. Grafmueller & S. Menegatti nโ€‰

co-author countries: Germany ๐Ÿ‡ฉ๐Ÿ‡ช United States of America ๐Ÿ‡บ๐Ÿ‡ธ
MeSH headings : Antineoplastic Combined Chemotherapy Protocols / chemistry; Antineoplastic Combined Chemotherapy Protocols / pharmacology; Breast Neoplasms / drug therapy; Chitosan / chemistry; Deoxycytidine / administration & dosage; Deoxycytidine / analogs & derivatives; Doxorubicin / administration & dosage; Drug Carriers / chemistry; Drug Liberation; Drug Synergism; Female; Humans; Hydrogels / chemistry; Polymers / chemistry; Gemcitabine
Sources: Web Of Science, ORCID
Added: September 3, 2019

2019 journal article

Targeted Capture of Chinese Hamster Ovary Host Cell Proteins: Peptide Ligand Discovery

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 20(7).

By: R. Lavoie n, A. Fazio n, R. Blackburn n, M. Goshe n, R. Carbonell n & S. Menegatti nโ€‰

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: therapeutic antibodies; host cell proteins; protein purification; peptide ligands
MeSH headings : Animals; CHO Cells; Chromatography, Affinity; Chromatography, Liquid; Cricetinae; Cricetulus; Humans; Peptides / chemistry; Peptides / isolation & purification; Proteomics / methods
Sources: Web Of Science, ORCID
Added: May 6, 2019

2019 journal article

Translating antibody-binding peptides into peptoid ligands with improved affinity and stability

JOURNAL OF CHROMATOGRAPHY A, 1602, 284โ€“299.

By: T. Bordelon, B. Bobay*, A. Murphy, H. Reese, C. Shanahan, F. Odeh, A. Broussard, C. Kormos, S. Menegatti nโ€‰

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: Peptoid ligands; Molecular docking; Affinity chromatography; Antibodies; Protein A mimetic
MeSH headings : Adsorption; Alkalies / chemistry; Amino Acid Sequence; Animals; Antibodies / metabolism; Antibody Affinity; Binding Sites; CHO Cells; Cattle; Cricetinae; Cricetulus; Humans; Immunoglobulin G / isolation & purification; Immunoglobulin G / metabolism; Ligands; Molecular Docking Simulation; Peptides / chemistry; Peptoids / chemistry; Protein Binding; Proteolysis; Temperature
Sources: Web Of Science, ORCID
Added: September 16, 2019

2019 journal article

Treating Tumors at Low Drug Doses Using an Aptamer-Peptide Synergistic Drug Conjugate

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 58(5), 1437โ€“1441.

By: A. Pusuluri*, V. Krishnanโ€‰*, V. Lenschโ€‰*, A. Sarodeโ€‰*, E. Bunyan*, D. Vogus*, S. Menegatti nโ€‰, H. Sohโ€‰*, S. Mitragotriโ€‰*

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: aptamer-drug conjugate; cancer; peptide scaffolds; synergy; targeted drug-delivery
MeSH headings : Antineoplastic Combined Chemotherapy Protocols / chemistry; Antineoplastic Combined Chemotherapy Protocols / therapeutic use; Aptamers, Nucleotide / chemistry; Camptothecin / chemistry; Camptothecin / therapeutic use; Cell Line; Cell Proliferation / drug effects; Doxorubicin / chemistry; Doxorubicin / therapeutic use; Drug Screening Assays, Antitumor; Humans; Maximum Tolerated Dose; Molecular Structure; Neoplasms / drug therapy; Neoplasms / pathology; Peptides / chemistry
Sources: Web Of Science, ORCID
Added: March 4, 2019

2018 journal article

Purification of human erythropoietin by affinity chromatography using cyclic peptide ligands

JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 1085, 1โ€“12.

By: W. Kish n, M. Roach n, H. Sachi*, A. Naik n, S. Menegatti nโ€‰ & R. Carbonell n

co-author countries: Japan ๐Ÿ‡ฏ๐Ÿ‡ต United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: Cyclic peptide ligand; Erythropoietin purification; Affinity chromatography; Chinese hamster ovary; Pichia pastoris
MeSH headings : Animals; CHO Cells; Chromatography, Affinity / methods; Cricetinae; Cricetulus; Erythropoietin / analysis; Erythropoietin / chemistry; Erythropoietin / isolation & purification; Erythropoietin / metabolism; Humans; Hydrogen-Ion Concentration; Peptides, Cyclic / chemistry; Peptides, Cyclic / metabolism; Pichia; Proteins
Sources: Web Of Science, ORCID
Added: August 6, 2018

2018 journal article

Quantum dot enabled lateral flow immunoassay for detection of cardiac biomarker NT-proBNP

Sensing and Bio-Sensing Research, 21, 46โ€“53.

By: M. Wilkinsโ€‰ n, B. Turner n, K. Rivera n, S. Menegatti nโ€‰ & M. Danieleโ€‰ n

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: NT-proBNP; cardiac biomarker; lateral flow; immunoassay; quantum dot
Sources: Crossref, ORCID
Added: February 24, 2020

2017 journal article

A hyaluronic acid conjugate engineered to synergistically and sequentially deliver gemcitabine and doxorubicin to treat triple negative breast cancer

Journal of Controlled Release, 267, 191โ€“202.

By: D. Vogus*, M. Evansโ€‰*, A. Pusuluri*, A. Barajas*, M. Zhangโ€‰*, V. Krishnanโ€‰*, M. Nowak*, S. Menegatti*โ€‰ ...

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: Drug combinations; Polymer drug conjugates; Synergy; Breast cancer; Gemcitabine; Doxorubcin
MeSH headings : Animals; Antibiotics, Antineoplastic / administration & dosage; Antibiotics, Antineoplastic / chemistry; Antimetabolites, Antineoplastic / administration & dosage; Antimetabolites, Antineoplastic / chemistry; Antineoplastic Combined Chemotherapy Protocols / administration & dosage; Antineoplastic Combined Chemotherapy Protocols / chemistry; Cell Line, Tumor; Cell Survival / drug effects; Deoxycytidine / administration & dosage; Deoxycytidine / analogs & derivatives; Deoxycytidine / chemistry; Dose-Response Relationship, Drug; Doxorubicin / administration & dosage; Doxorubicin / chemistry; Drug Carriers / administration & dosage; Drug Carriers / chemistry; Drug Liberation; Drug Synergism; Humans; Hyaluronic Acid / administration & dosage; Hyaluronic Acid / chemistry; Mice; Mice, Inbred BALB C; Prodrugs / administration & dosage; Prodrugs / chemistry; Triple Negative Breast Neoplasms / drug therapy; Gemcitabine
Sources: Crossref, ORCID
Added: February 24, 2020

2017 journal article

Design, selection, and development of cyclic peptide ligands for human erythropoietin

JOURNAL OF CHROMATOGRAPHY A, 1500, 105โ€“120.

By: W. Kish n, H. Sachi*, A. Naik n, M. Roach n, B. Bobay n, R. Blackburn n, S. Menegatti nโ€‰, R. Carbonell n

co-author countries: Japan ๐Ÿ‡ฏ๐Ÿ‡ต United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: Erythropoietin; Cyclic peptide ligands; Ligand screening; Affinity chromatography; Affinity maturation; In-silico docking
MeSH headings : Amino Acid Sequence; Amino Acids / chemistry; Erythropoietin / chemistry; Humans; Kinetics; Ligands; Molecular Sequence Data; Peptides, Cyclic / chemistry; Peptides, Cyclic / isolation & purification; Protein Binding
Sources: Web Of Science, ORCID
Added: August 6, 2018

2016 journal article

A combined approach for predicting the cytotoxic effect of drug-nanoaggregates

Journal of Materials Chemistry B, 4(40), 6516โ€“6523.

By: M. Wojnilowiczโ€‰*, M. Tortora*, B. Bobay*, E. Santiso nโ€‰, M. Caruso*, L. Micheliโ€‰*, M. Venanziโ€‰*, S. Menegatti nโ€‰, F. Cavalieriโ€‰*

co-author countries: Australia ๐Ÿ‡ฆ๐Ÿ‡บ France ๐Ÿ‡ซ๐Ÿ‡ท Italy ๐Ÿ‡ฎ๐Ÿ‡น United States of America ๐Ÿ‡บ๐Ÿ‡ธ
Sources: Crossref, ORCID
Added: March 26, 2019

2016 journal article

DAFODIL: A novel liposome-encapsulated synergistic combination of doxorubicin and 5FU for low dose chemotherapy

JOURNAL OF CONTROLLED RELEASE, 229, 154โ€“162.

By: K. Camacho*, S. Menegatti nโ€‰, D. Vogus*, A. Pusuluri*, Z. Fuchsโ€‰*, M. Jarvisโ€‰*, M. Zakrewskyโ€‰*, M. Evansโ€‰*, R. Chen*, S. Mitragotriโ€‰*

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: Drug combinations; Synergistic; Chemotherapy; Liposomes; Nanoparticles
MeSH headings : Animals; Antibiotics, Antineoplastic / administration & dosage; Antibiotics, Antineoplastic / chemistry; Antibiotics, Antineoplastic / pharmacokinetics; Antibiotics, Antineoplastic / therapeutic use; Antimetabolites, Antineoplastic / administration & dosage; Antimetabolites, Antineoplastic / chemistry; Antimetabolites, Antineoplastic / pharmacokinetics; Antimetabolites, Antineoplastic / therapeutic use; Cell Line; Cell Line, Tumor; Doxorubicin / administration & dosage; Doxorubicin / chemistry; Doxorubicin / pharmacokinetics; Doxorubicin / therapeutic use; Drug Combinations; Female; Fluorouracil / administration & dosage; Fluorouracil / chemistry; Fluorouracil / pharmacokinetics; Fluorouracil / therapeutic use; Humans; Liposomes; Mice, Inbred BALB C; Neoplasms / drug therapy; Neoplasms / metabolism; Neoplasms / pathology; Polyethylene Glycols / chemistry; Tryptophan / chemistry; Tumor Burden / drug effects
Sources: Web Of Science, ORCID
Added: August 6, 2018

2016 journal article

De Novo Design of Skin-Penetrating Peptides for Enhanced Transdermal Delivery of Peptide Drugs

ADVANCED HEALTHCARE MATERIALS, 5(5), 602โ€“609.

By: S. Menegatti nโ€‰, M. Zakrewskyโ€‰*, S. Kumarโ€‰*, J. De Oliveira*, J. Muraski & S. Mitragotriโ€‰*

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
MeSH headings : Administration, Cutaneous; Adult; Amino Acid Sequence; Cell Survival / drug effects; Computer Simulation; Cyclosporine / metabolism; Cyclosporine / pharmacology; Drug Delivery Systems / methods; Drug Design; Epidermal Cells; Humans; Keratinocytes / cytology; Keratinocytes / drug effects; Keratins / metabolism; Mass Spectrometry; Peptide Library; Peptides / administration & dosage; Peptides / chemistry; Peptides / pharmacology; Peptides / toxicity; Pharmaceutical Preparations / administration & dosage; Skin / drug effects; Skin Absorption / drug effects; Thermodynamics
Sources: Web Of Science, ORCID
Added: August 6, 2018

2016 journal article

Design of protease-resistant peptide ligands for the purification of antibodies from human plasma

Journal of Chromatography A, 1445, 93โ€“104.

By: S. Menegatti nโ€‰, B. Bobay n, K. Ward n, T. Islam n, W. Kish n, A. Naik n, R. Carbonell n

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: Peptide affinity ligands; Polyclonal antibodies; Affinity chromatography; Proteolysis; Protease; Molecular docking
MeSH headings : Animals; Antibodies / isolation & purification; Binding Sites; Blood Chemical Analysis / methods; Chromatography, Affinity; Chymotrypsin / metabolism; Humans; Ligands; Peptides / chemistry; Protein Binding; Trypsin / metabolism
Sources: Web Of Science, ORCID
Added: August 6, 2018

2016 journal article

Low-molecular-weight polymer-drug conjugates for synergistic anticancer activity of camptothecin and doxorubicin combinations

Nanomedicine, 11(9), 1139โ€“1151.

By: K. Camacho*, S. Menegatti nโ€‰ & S. Mitragotriโ€‰*

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: combination chemotherapy; drug delivery; linker chemistry; low-molecular-weight conjugates; polymer-drug conjugates
MeSH headings : Antineoplastic Combined Chemotherapy Protocols; Camptothecin / administration & dosage; Camptothecin / chemistry; Cell Line, Tumor; Cell Proliferation / drug effects; Doxorubicin / administration & dosage; Doxorubicin / chemistry; Drug Delivery Systems; Drug Synergism; Humans; Hyaluronic Acid / chemistry; Molecular Weight; Neoplasms / drug therapy; Polymers / chemistry; Polyvinyl Alcohol / chemistry
Sources: Web Of Science, ORCID
Added: August 6, 2018

2015 journal article

Elasticity of Nanoparticles Influences Their Blood Circulation, Phagocytosis, Endocytosis, and Targeting

ACS Nano, 9(3), 3169โ€“3177.

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: elasticity; nanogel; nanoemulsion; biodistribution; circulation; targeting; nanomedicine; nanoparticles
MeSH headings : Animals; Blood / metabolism; Cell Line, Tumor; Elastic Modulus; Humans; Hydrogels / chemistry; Hydrogels / metabolism; Hydrogels / pharmacokinetics; Mice; Nanoparticles; Particle Size; Phagocytosis; Polyethylene Glycols / chemistry; Structure-Activity Relationship; Tissue Distribution
Sources: Crossref, ORCID
Added: February 24, 2020

2015 journal article

Peptides as skin penetration enhancers: Mechanisms of action

Journal of Controlled Release, 199, 168โ€“178.

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: Cell penetrating peptide; Cyclosporine; Keratin; Transporter; Topical; Transcellular
MeSH headings : Cells, Cultured; Computer Simulation; Cyclosporine / administration & dosage; Cyclosporine / pharmacokinetics; Drug Carriers / adverse effects; Drug Carriers / chemistry; Drug Carriers / pharmacology; Humans; Keratinocytes / drug effects; Keratins / metabolism; Lipids / chemistry; Peptides / adverse effects; Peptides / chemistry; Peptides / pharmacology; Skin / chemistry; Skin / drug effects; Skin Absorption / drug effects; Spectroscopy, Fourier Transform Infrared; Structure-Activity Relationship; Water Loss, Insensible / drug effects
Sources: Crossref, ORCID
Added: February 24, 2020

2015 journal article

Synergistic antitumor activity of camptothecinโ€“doxorubicin combinations and their conjugates with hyaluronic acid

Journal of Controlled Release, 210, 198โ€“207.

By: K. Camacho*, S. Kumarโ€‰*, S. Menegatti*โ€‰, D. Vogus*, A. Anselmoโ€‰* & S. Mitragotriโ€‰*

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: Chemotherapy; Drug combinations; Polymer drug conjugate; Synergistic
MeSH headings : Animals; Antineoplastic Agents, Phytogenic / administration & dosage; Antineoplastic Agents, Phytogenic / chemistry; Antineoplastic Combined Chemotherapy Protocols / administration & dosage; Apoptosis / drug effects; Camptothecin / administration & dosage; Camptothecin / chemistry; Cell Line, Tumor; Doxorubicin / administration & dosage; Doxorubicin / chemistry; Drug Synergism; Female; Humans; Hyaluronic Acid / administration & dosage; Hyaluronic Acid / chemistry; Mice, Inbred BALB C; Neoplasms / drug therapy; Neoplasms / pathology; Topoisomerase I Inhibitors / administration & dosage; Topoisomerase I Inhibitors / chemistry; Topoisomerase II Inhibitors / administration & dosage; Topoisomerase II Inhibitors / chemistry; Tumor Burden / drug effects
Sources: Crossref, ORCID
Added: August 28, 2020

2015 journal article

Synthesis and Characterization of a Self-Fluorescent Hyaluronic Acid-Based Gel for Dermal Applications

Advanced Healthcare Materials, 4(15), 2297โ€“2305.

By: S. Menegatti*โ€‰, N. Ruocco*, S. Kumarโ€‰*, M. Zakrewskyโ€‰*, J. Sanchez De Oliveira*, M. Helgesonโ€‰*, G. Leal*, S. Mitragotriโ€‰*

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
MeSH headings : Animals; Biocompatible Materials / chemistry; Cell Line; Cell Proliferation / drug effects; Delayed-Action Preparations; Drug Liberation; Humans; Hyaluronic Acid / chemistry; Hydrogels / chemistry; Keratinocytes / drug effects; Keratinocytes / metabolism; Polymers; Rheology; Skin / drug effects; Skin / metabolism; Swine; Tissue Engineering
Sources: Crossref, ORCID
Added: February 24, 2020

2014 journal article

Platelet-like Nanoparticles: Mimicking Shape, Flexibility, and Surface Biology of Platelets To Target Vascular Injuries

ACS Nano, 8(11), 11243โ€“11253.

By: A. Anselmoโ€‰*, C. Modery-Pawlowski*, S. Menegatti*โ€‰, S. Kumarโ€‰*, D. Vogus*, L. Tian*, M. Chenโ€‰*, T. Squiresโ€‰*, A. Sen Guptaโ€‰*, S. Mitragotriโ€‰*

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: platelets; synthetic cells; layer-by-layer; nanotechnology; hemostat; vascular targeting
MeSH headings : Animals; Blood Platelets / pathology; Cell Adhesion; Cell Shape; Female; Mice; Mice, Inbred BALB C; Microscopy, Electron, Scanning; Nanoparticles; Platelet Aggregation; Spectroscopy, Fourier Transform Infrared; Vascular System Injuries / pathology
Sources: Crossref, ORCID
Added: August 28, 2020

2013 journal article

Peptide-based affinity adsorbents with high binding capacity for the purification of monoclonal antibodies

Industrial & Engineering Chemistry Research, 52(26), 8800โ€“8811.

By: W. Kish n, A. Naik n, S. Menegatti nโ€‰ & R. Carbonell n

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
Sources: Web Of Science, ORCID
Added: August 6, 2018

2013 journal article

Reversible cyclic peptide libraries for the discovery of affinity ligands

Analytical Chemistry, 85(19), 9229โ€“9237.

By: S. Menegatti nโ€‰, K. Ward n, A. Naik n, W. Kish n, R. Blackburn n & R. Carbonell n

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
MeSH headings : Ligands; Molecular Structure; Peptide Library; Peptides, Cyclic / analysis; Tandem Mass Spectrometry
Sources: Web Of Science, ORCID
Added: August 6, 2018

2013 journal article

mRNA display selection and solid-phase synthesis of Fc-binding cyclic peptide affinity ligands

Biotechnology and Bioengineering, 110(3), 857โ€“870.

By: S. Menegatti nโ€‰, M. Hussain n, A. Naik n, R. Carbonell n & B. Rao n

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: cyclic peptide; mRNA display; Fc binding; affinity ligand; library
MeSH headings : Humans; Immunoglobulin Fc Fragments / metabolism; Peptide Library; Peptides, Cyclic / chemistry; Peptides, Cyclic / genetics; Peptides, Cyclic / isolation & purification; Peptides, Cyclic / metabolism; Protein Binding; Protein Engineering / methods; RNA, Messenger / genetics; Solid-Phase Synthesis Techniques / methods
Sources: Web Of Science, ORCID
Added: August 6, 2018

2012 journal article

Alkaline-stable peptide ligand affinity adsorbents for the purification of biomolecules

Journal of Chromatography A, 1245, 55โ€“64.

By: S. Menegatti nโ€‰, A. Naik n, P. Gurgel n & R. Carbonell n

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: Peptide ligand; Affinity adsorbent; NaOH stability; Modification of surface chemistry; Solid-phase peptide synthesis; Cleaning-in-place
MeSH headings : Adsorption; Alkalies / chemistry; Chromatography, Affinity / instrumentation; Chromatography, Affinity / methods; Immunoglobulin G / chemistry; Immunoglobulin G / isolation & purification; Ligands; Peptides / chemistry; Protein Binding
Sources: Web Of Science, ORCID
Added: August 6, 2018

2012 journal article

Process for purification of monoclonal antibody expressed in transgenic Lemna plant extract using dextran-coated charcoal and hexamer peptide affinity resin

Journal of Chromatography A, 1260, 61โ€“66.

By: A. Naik n, S. Menegatti nโ€‰, H. Reese n, P. Gurgel n & R. Carbonell n

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: Dextran-coated charcoal; Transgenic plants; Hexapeptide ligand; IgG purification; Monoclonal antibody; Phenolics; Lemna minor
MeSH headings : Antibodies, Monoclonal / isolation & purification; Antibodies, Monoclonal / metabolism; Araceae / chemistry; Araceae / metabolism; Charcoal / chemistry; Chromatography, Affinity / methods; Dextrans / chemistry; Humans; Immunoglobulin G / isolation & purification; Immunoglobulin G / metabolism; Peptides / chemistry; Peptides / metabolism; Plant Extracts / chemistry; Plants, Genetically Modified / chemistry; Plants, Genetically Modified / metabolism; Protein Binding; Staphylococcal Protein A / chemistry; Staphylococcal Protein A / isolation & purification
Sources: Web Of Science, ORCID
Added: August 6, 2018

2012 journal article

Purification of polyclonal antibodies from Cohn fraction II + III, skim milk, and whey by affinity chromatography using a hexamer peptide ligand

Journal of Separation Science, 35(22), 3139โ€“3148.

By: S. Menegatti*โ€‰, A. Naik, P. Gurgel & R. Carbonell n

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: Affinity chromatography; Immunoglobulin G; Milk; Peptide ligands; Plasma
MeSH headings : Animals; Antibodies / chemistry; Antibodies / isolation & purification; Blood Proteins / chemistry; Blood Proteins / isolation & purification; Cattle; Chromatography, Affinity / instrumentation; Chromatography, Affinity / methods; Humans; Ligands; Milk / chemistry; Milk Proteins / chemistry; Milk Proteins / isolation & purification; Peptides / chemistry; Whey Proteins
Sources: Crossref, ORCID
Added: August 28, 2020

2011 journal article

Performance of hexamer peptide ligands for affinity purification of immunoglobulin G from commercial cell culture media

Journal of Chromatography A, 1218(13), 1691โ€“1700.

By: A. Naik n, S. Menegatti nโ€‰, P. Gurgel n & R. Carbonell n

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: Hexapeptide ligand; IgG purification; Monoclonal antibody; Affinity chromatography; Regeneration
MeSH headings : Adsorption; Animals; Antibodies, Monoclonal / chemistry; Antibodies, Monoclonal / isolation & purification; CHO Cells; Caprylates; Cell Culture Techniques; Chromatography, Affinity / methods; Cricetinae; Cricetulus; Culture Media; Electrophoresis, Polyacrylamide Gel; Humans; Immunoglobulin G / chemistry; Immunoglobulin G / isolation & purification; Oligopeptides / chemistry; Phosphoric Acids; Protein Binding; Sodium Chloride; Urea
Sources: Web Of Science, ORCID
Added: August 6, 2018

Employment

Updated: November 14th, 2018 12:31

2015 - present

North Carolina State University Raleigh, NC, US
Assistant Professor Chemical and Biomolecular Engineering

Education

Updated: November 14th, 2018 12:33

2009 - 2013

North Carolina State University Raleigh, NC, US
Ph.D. Chemical and Biomolecular Engineering

2006 - 2008

Universitร  degli Studi di Bologna Bologna, Emilia-Romagna, IT
M.Sc. Ingegneria Chimica