Stefano Menegatti

Barozzi, A., Lavoie, R. A., Day, K. N., Prodromou, R., & Menegatti, S. (2020). Affibody-Binding Ligands. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 21(11). https://doi.org/10.3390/ijms21113769

Schneible, J. D., Young, A. T., Daniele, M. A., & Menegatti, S. (2020). Chitosan Hydrogels for Synergistic Delivery of Chemotherapeutics to Triple Negative Breast Cancer Cells and Spheroids. PHARMACEUTICAL RESEARCH, 37(7). https://doi.org/10.1007/s11095-020-02864-2

Reese, H. R., Shanahan, C. C., Lembo, J., Tsonev, L., Hirsh, A., & Menegatti, S. (2020). Chromatographic assay to probe the binding energy and mechanisms of homologous proteins to surface-bound ligands. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 1136. https://doi.org/10.1016/j.jchromb.2019.121927

Smith, R. J., Fabiani, T., Wang, S., Ramesh, S., Khan, S., Santiso, E., … Menegatti, S. (2020). Exploring the physicochemical and morphological properties of peptide-hybridized dendrimers (DendriPeps) and their aggregates. JOURNAL OF POLYMER SCIENCE. https://doi.org/10.1002/pol.20200277

Raghuvanshi, K., Zhu, C., Ramezani, M., Menegatti, S., Santiso, E. E., Mason, D., … Abolhasani, M. (2020). Highly Efficient 1-Octene Hydroformylation at Low Syngas Pressure: From Single-Droplet Screening to Continuous Flow Synthesis. ACS CATALYSIS, 10(14), 7535–7542. https://doi.org/10.1021/acscatal.0c01515

Schneible, J. D., Shi, K., Young, A. T., Ramesh, S., He, N., Dowdey, C. E., … Menegatti, S. (2020). Modified gaphene oxide (GO) particles in peptide hydrogels: a hybrid system enabling scheduled delivery of synergistic combinations of chemotherapeutics. JOURNAL OF MATERIALS CHEMISTRY B, 8(17), 3852–3868. https://doi.org/10.1039/d0tb00064g

Cutright, C., Finkelstein, R., Orlowski, E., McIntosh, E., Brotherton, Z., Fabiani, T., … Menegatti, S. (2020). Nonwoven fiber mats with thermo-responsive permeability to inorganic and organic electrolytes. JOURNAL OF MEMBRANE SCIENCE, 616. https://doi.org/10.1016/j.memsci.2020.118439

Reese, H. R., Xiao, X., Shanahan, C. C., Driessche, G. A., Fourches, D., Carbonell, R. G., … Menegatti, S. (2020). Novel peptide ligands for antibody purification provide superior clearance of host cell protein impurities. JOURNAL OF CHROMATOGRAPHY A, 1625. https://doi.org/10.1016/j.chroma.2020.461237

Reese, H., Bordelon, T., Shanahan, C., Crapanzano, M., Sly, J., & Menegatti, S. (2020). Novel peptoid-based adsorbents for purifying IgM and IgG from polyclonal and recombinant sources. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 1137. https://doi.org/10.1016/j.jchromb.2019.121909

Cutright, C., Brotherton, Z., Alexander, L., Harris, J., Shi, K., Khan, S., … Menegatti, S. (2020). Packing density, homogeneity, and regularity: Quantitative correlations between topology and thermoresponsive morphology of PNIPAM-co-PAA microgel coatings. APPLIED SURFACE SCIENCE, 508. https://doi.org/10.1016/j.apsusc.2019.145129

Bacon, K., Lavoie, A., Rao, B. M., Daniele, M., & Menegatti, S. (2020). [Review of Past, Present, and Future of Affinity-based Cell Separation Technologies]. ACTA BIOMATERIALIA, 112, 29–51. https://doi.org/10.1016/j.actbio.2020.05.004

Reese, H. R., Shanahan, C. C., Proulx, C., & Menegatti, S. (2020). [Review of Peptide science: A "rule model" for new generations of peptidomimetics]. ACTA BIOMATERIALIA, 102, 35–74. https://doi.org/10.1016/j.actbio.2019.10.045

Day, K., Schneible, J. D., Young, A. T., Pozdin, V. A., Driessche, G., Gaffney, L. A., … Menegatti, S. (2020). Photoinduced reconfiguration to control the protein-binding affinity of azobenzene-cyclized peptides. JOURNAL OF MATERIALS CHEMISTRY B, 8(33), 7413–7427. https://doi.org/10.1039/d0tb01189d

Gilbertie, J. M., Schaer, T. P., Schubert, A. G., Jacob, M. E., Menegatti, S., Lavoie, R. A., & Schnabel, L. V. (2020). Platelet-rich plasma lysate displays antibiofilm properties and restores antimicrobial activity against synovial fluid biofilms in vitro. JOURNAL OF ORTHOPAEDIC RESEARCH. https://doi.org/10.1002/jor.24584

Reese, H., Bordelon, T., Odeh, F., Broussard, A., Kormos, C., Murphy, A., … Menegatti, S. (2020). Purification of animal immunoglobulin G (IgG) using peptoid affinity ligands. BIOTECHNOLOGY PROGRESS. https://doi.org/10.1002/btpr.2994

Saberi-Bosari, S., Omary, M., Lavoie, A., Prodromou, R., Day, K., Menegatti, S., & San-Miguel, A. (2019). Affordable Microfluidic Bead-Sorting Platform for Automated Selection of Porous Particles Functionalized with Bioactive Compounds. SCIENTIFIC REPORTS, 9. https://doi.org/10.1038/s41598-019-42869-5

Smith, R. J., Gorman, C. B., & Menegatti, S. (2019). DendriPeps: Expanding Dendrimer Functionality by Hybridizing Poly(amidoamine) (PAMAM) Scaffolds with Peptide Segments. MACROMOLECULAR RAPID COMMUNICATIONS. https://doi.org/10.1002/marc.201900325

Day, K., Prodromou, R., Bosari, S. S., Lavoie, A., Omary, M., Market, C., … Menegatti, S. (2019). Discovery and Evaluation of Peptide Ligands for Selective Adsorption and Release of Cas9 Nuclease on Solid Substrates. BIOCONJUGATE CHEMISTRY, 30(12), 3057–3068. https://doi.org/10.1021/acs.bioconjchem.9b00703

Lavoie, R. A., Fazio, A., Carbonell, R. G., & Menegatti, S. (2019). Multiplexed Competitive Screening of One-Bead-One-Component Combinatorial Libraries Using a ClonePix 2 Colony Sorter. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 20(20). https://doi.org/10.3390/ijms20205119

Islam, T., Naik, A. D., Hashimoto, Y., Menegatti, S., & Carbonell, R. G. (2019). Optimization of Sequence, Display, and Mode of Operation of IgG-Binding Peptide Ligands to Develop Robust, High-Capacity Affinity Adsorbents That Afford High IgG Product Quality. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 20(1). https://doi.org/10.3390/ijms20010161

Bacon, K., Burroughs, M., Blain, A., Menegatti, S., & Rao, B. M. (2019). Screening Yeast Display Libraries against Magnetized Yeast Cell Targets Enables Efficient Isolation of Membrane Protein Binders. ACS COMBINATORIAL SCIENCE, 21(12), 817–832. https://doi.org/10.1021/acscombsci.9b00147

Naika, A. D., Islam, T., Terasaka, T., Ohara, Y., Hashimoto, Y., Menegatti, S., & Carbonell, R. (2019). Silica resins and peptide ligands to develop disposable affinity adsorbents for antibody purification. BIOCHEMICAL ENGINEERING JOURNAL, 145, 53–61. https://doi.org/10.1016/j.bej.2018.07.011

Schneible, J. D., Singhal, A., Lilova, R. L., Hall, C. K., Grafmueller, A., & Menegatti, S. (2019). Tailoring the Chemical Modification of Chitosan Hydrogels to Fine-Tune the Release of a Synergistic Combination of Chemotherapeutics. BIOMACROMOLECULES, 20(8), 3126–3141. https://doi.org/10.1021/acs.biomac.9b00707

Lavoie, R. A., Fazio, A., Blackburn, R. K., Goshe, M. B., Carbonell, R. G., & Menegatti, S. (2019). Targeted Capture of Chinese Hamster Ovary Host Cell Proteins: Peptide Ligand Discovery. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 20(7). https://doi.org/10.3390/ijms20071729

Lavoie, R. A., Fazio, A., Williams, T. I., Carbonell, R., & Menegatti, S. (2019). Targeted capture of Chinese hamster ovary host cell proteins: Peptide ligand binding by proteomic analysis. BIOTECHNOLOGY AND BIOENGINEERING. https://doi.org/10.1002/bit.27213

Bordelon, T., Bobay, B., Murphy, A., Reese, H., Shanahan, C., Odeh, F., … Menegatti, S. (2019). Translating antibody-binding peptides into peptoid ligands with improved affinity and stability. JOURNAL OF CHROMATOGRAPHY A, 1602, 284–299. https://doi.org/10.1016/j.chroma.2019.05.047

Pusuluri, A., Krishnan, V., Lensch, V., Sarode, A., Bunyan, E., Vogus, D. R., … Mitragotri, S. (2019). Treating Tumors at Low Drug Doses Using an Aptamer-Peptide Synergistic Drug Conjugate. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 58(5), 1437–1441. https://doi.org/10.1002/anie.201812650

Kish, W. S., Roach, M. K., Sachi, H., Naik, A. D., Menegatti, S., & Carbonell, R. G. (2018). Purification of human erythropoietin by affinity chromatography using cyclic peptide ligands. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences, 1085, 1–12. https://doi.org/10.1016/j.jchromb.2018.03.039

Wilkins, M. D., Turner, B. L., Rivera, K. R., Menegatti, S., & Daniele, M. (2018). Quantum dot enabled lateral flow immunoassay for detection of cardiac biomarker NT-proBNP. Sensing and Bio-Sensing Research, 21, 46–53. https://doi.org/10.1016/J.SBSR.2018.10.002

Vogus, D. R., Evans, M. A., Pusuluri, A., Barajas, A., Zhang, M., Krishnan, V., … Mitragotri, S. (2017). A hyaluronic acid conjugate engineered to synergistically and sequentially deliver gemcitabine and doxorubicin to treat triple negative breast cancer. Journal of Controlled Release, 267, 191–202. https://doi.org/10.1016/J.JCONREL.2017.08.016

Kish, W. S., Sachi, H., Naik, A. D., Roach, M. K., Bobay, B. G., Blackburn, R. K., … Carbonell, R. G. (2017). Design, selection, and development of cyclic peptide ligands for human erythropoietin. Journal of Chromatography. A, 1500, 105–120. https://doi.org/10.1016/j.chroma.2017.04.019

Wojnilowicz, M., Tortora, M., Bobay, B. G., Santiso, E., Caruso, M., Micheli, L., … Cavalieri, F. (2016). A combined approach for predicting the cytotoxic effect of drug-nanoaggregates. Journal of Materials Chemistry B, 4(40), 6516–6523. https://doi.org/10.1039/C6TB02105K

Camacho, K. M., Menegatti, S., Vogus, D. R., Pusuluri, A., Fuchs, Z., Jarvis, M., … Mitragotri, S. (2016). DAFODIL: A novel liposome-encapsulated synergistic combination of doxorubicin and 5FU for low dose chemotherapy. Journal of Controlled Release, 229, 154–162. https://doi.org/10.1016/j.jconrel.2016.03.027

Menegatti, S., Zakrewsky, M., Kumar, S., De Oliveira, J. S., Muraski, J. A., & Mitragotri, S. (2016). De Novo design of skin-penetrating peptides for enhanced transdermal delivery of peptide drugs. Advanced Healthcare Materials, 5(5), 602–609. https://doi.org/10.1002/adhm.201500634

Menegatti, S., Bobay, B. G., Ward, K. L., Islam, T., Kish, W. S., Naik, A. D., & Carbonell, R. G. (2016). Design of protease-resistant peptide ligands for the purification of antibodies from human plasma. Journal of Chromatography. A, 1445, 93–104. https://doi.org/10.1016/j.chroma.2016.03.087

Camacho, K. M., Menegatti, S., & Mitragotri, S. (2016). Low-molecular-weight polymer-drug conjugates for synergistic anticancer activity of camptothecin and doxorubicin combinations. Nanomedicine, 11(9), 1139–1151. https://doi.org/10.2217/nnm.16.33

Anselmo, A. C., Zhang, M., Kumar, S., Vogus, D. R., Menegatti, S., Helgeson, M. E., & Mitragotri, S. (2015). Elasticity of Nanoparticles Influences Their Blood Circulation, Phagocytosis, Endocytosis, and Targeting. ACS Nano, 9(3), 3169–3177. https://doi.org/10.1021/ACSNANO.5B00147

Kumar, S., Zakrewsky, M., Chen, M., Menegatti, S., Muraski, J. A., & Mitragotri, S. (2015). Peptides as skin penetration enhancers: Mechanisms of action. Journal of Controlled Release, 199, 168–178. https://doi.org/10.1016/J.JCONREL.2014.12.006

Camacho, K. M., Kumar, S., Menegatti, S., Vogus, D. R., Anselmo, A. C., & Mitragotri, S. (2015). Synergistic antitumor activity of camptothecin–doxorubicin combinations and their conjugates with hyaluronic acid. Journal of Controlled Release, 210, 198–207. https://doi.org/10.1016/J.JCONREL.2015.04.031

Menegatti, S., Ruocco, N., Kumar, S., Zakrewsky, M., Sanchez De Oliveira, J., Helgeson, M. E., … Mitragotri, S. (2015). Synthesis and Characterization of a Self-Fluorescent Hyaluronic Acid-Based Gel for Dermal Applications. Advanced Healthcare Materials, 4(15), 2297–2305. https://doi.org/10.1002/ADHM.201500619

Anselmo, A. C., Modery-Pawlowski, C. L., Menegatti, S., Kumar, S., Vogus, D. R., Tian, L. L., … Mitragotri, S. (2014). Platelet-like Nanoparticles: Mimicking Shape, Flexibility, and Surface Biology of Platelets To Target Vascular Injuries. ACS Nano, 8(11), 11243–11253. https://doi.org/10.1021/NN503732M

Kish, W. S., Naik, A. D., Menegatti, S., & Carbonell, R. G. (2013). Peptide-based affinity adsorbents with high binding capacity for the purification of monoclonal antibodies. Industrial & Engineering Chemistry Research, 52(26), 8800–8811. https://doi.org/10.1021/ie302345w

Menegatti, S., Ward, K. L., Naik, A. D., Kish, W. S., Blackburn, R. K., & Carbonell, R. G. (2013). Reversible cyclic peptide libraries for the discovery of affinity ligands. Analytical Chemistry, 85(19), 9229–9237. https://doi.org/10.1021/ac401954k

Menegatti, S., Hussain, M., Naik, A. D., Carbonell, R. G., & Rao, B. M. (2013). mRNA display selection and solid-phase synthesis of Fc-binding cyclic peptide affinity ligands. Biotechnology and Bioengineering, 110(3), 857–870. https://doi.org/10.1002/bit.24760

Menegatti, S., Naik, A. D., Gurgel, P. V., & Carbonell, R. G. (2012). Alkaline-stable peptide ligand affinity adsorbents for the purification of biomolecules. Journal of Chromatography. A, 1245, 55–64. https://doi.org/10.1016/j.chroma.2012.04.072

Naik, A. D., Menegatti, S., Reese, H. R., Gurgel, P. V., & Carbonell, R. G. (2012). Process for purification of monoclonal antibody expressed in transgenic Lemna plant extract using dextran-coated charcoal and hexamer peptide affinity resin. Journal of Chromatography. A, 1260, 61–66. https://doi.org/10.1016/j.chroma.2012.08.043

Menegatti, S., Naik, A. D., Gurgel, P. V., & Carbonell, R. G. (2012). Purification of polyclonal antibodies from Cohn fraction II + III, skim milk, and whey by affinity chromatography using a hexamer peptide ligand. Journal of Separation Science, 35(22), 3139–3148. https://doi.org/10.1002/jssc.201200199

Naik, A. D., Menegatti, S., Gurgel, P. V., & Carbonell, R. G. (2011). Performance of hexamer peptide ligands for affinity purification of immunoglobulin G from commercial cell culture media. Journal of Chromatography. A, 1218(13), 1691–1700. https://doi.org/10.1016/j.chroma.2010.11.071