Sophia Noel Carrell

Works (2)

Updated: July 5th, 2023 15:35

2017 article

A facilitated diffusion mechanism establishes the Drosophila Dorsal gradient

Carrell, S. N., O'Connell, M. D., Jacobsen, T., Allen, A. E., Smith, S. M., & Reeves, G. T. (2017, January 1). Development.

By: S. Carrell n, M. O'Connell n, T. Jacobsen n, A. Allen n, S. Smith  n & G. Reeves n

author keywords: Morphogen; Tissue patterning; Mathematical modeling; Dorsal; Cactus; Shuttling
MeSH headings : Animals; Animals, Genetically Modified; Biophysical Phenomena; Body Patterning / genetics; Body Patterning / physiology; Computer Simulation; DNA-Binding Proteins / genetics; DNA-Binding Proteins / physiology; Drosophila Proteins / genetics; Drosophila Proteins / physiology; Drosophila melanogaster / embryology; Drosophila melanogaster / genetics; Drosophila melanogaster / physiology; Facilitated Diffusion; Female; Models, Biological; Nuclear Proteins / genetics; Nuclear Proteins / physiology; Phosphoproteins / genetics; Phosphoproteins / physiology; Signal Transduction; Toll-Like Receptors / genetics; Toll-Like Receptors / physiology; Transcription Factors / genetics; Transcription Factors / physiology
topics (OpenAlex): Developmental Biology and Gene Regulation; Cellular Mechanics and Interactions; Bone Metabolism and Diseases
TL;DR: Dorsal, a transcription factor that patterns the Drosophila dorsal-ventral axis, accumulates at the embryo ventral midline, and model-guided experiments show that the inhibitor Cactus shuttles Dorsal to the ventral side. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

2015 journal article

Imaging the dorsal-ventral axis of live and fixed Drosophila melanogaster embryos

Tissue Morphogenesis: Methods and Protocols, 1189, 63–78.

By: S. Carrell & G. Reeves

Source: NC State University Libraries
Added: August 6, 2018

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