Siddhartha Thakur

Also known as: Sid

Antimicrobial Resistance, Food Safety, Public Health, Genotyping, Whole Genome Sequencing, Global Health, Infectious Diseases

Works (102)

Updated: May 1st, 2024 05:02

2024 article

Antimicrobial resistance in food-borne pathogens at the human-animal interface: Results from a large surveillance study in India

Mahindroo, J., Narayan, C., Modgil, V., Kaur, H., Shahi, V., Sharma, B., … Taneja, N. (2024, June). ONE HEALTH, Vol. 18.

By: J. Mahindroo*, C. Narayan*, V. Modgil*, H. Kaur*, V. Shahi*, B. Sharma*, R. Jain, S. Thakur n, B. Mohan*, N. Taneja*

author keywords: Foodborne bacteria; Campylobacter spp.; E. coli; Antibiotic resistance; One health; India
Sources: Web Of Science, NC State University Libraries
Added: March 11, 2024

2024 journal article

Characteristics of antimicrobial resistance in <i>Escherichia coli</i> isolated from retail meat products in North Carolina

PLOS ONE, 19(1).

By: M. Aworh n, S. Thakur n, C. Gensler n, E. Harrell n, L. Harden n, P. Fedorka-Cray n, M. Jacob n

TL;DR: The lack of an association between MDR E. coli in retail meat and antibiotic use claim, including those with no indication of antimicrobial use, suggests that additional research is required to understand the origin of resistance. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: February 26, 2024

2024 article

Megaplasmid Dissemination in Multidrug-Resistant <i>Salmonella</i> Serotypes from Backyard and Commercial Broiler Production Systems in the Southeastern United States

Parzygnat, J. L., Crespo, R., Fosnaught, M., Muyyarrikkandy, M., Hull, D., Harden, L., & Thakur, S. (2024, April 18). FOODBORNE PATHOGENS AND DISEASE, Vol. 4.

By: J. Parzygnat n, R. Crespo n, M. Fosnaught n, M. Muyyarrikkandy*, D. Hull*, L. Harden n, S. Thakur n

author keywords: Salmonella; broilers; antimicrobial resistance; whole-genome sequencing; backyard poultry
Sources: Web Of Science, NC State University Libraries
Added: April 29, 2024

2024 journal article

Phenotypic and Genotypic Characterizations of Antimicrobial-Resistant <i>Escherichia coli</i> Isolates from Diverse Retail Meat Samples in North Carolina During 2018-2019

FOODBORNE PATHOGENS AND DISEASE, 1.

By: A. Abdelrahim n, E. Harrell n, P. Fedorka-Cray n, M. Jacob n & S. Thakur n

author keywords: antimicrobial resistance; Escherichia coli; retail meats; whole genome sequencing; antimicrobial susceptibility testing; multidrug resistance
Sources: Web Of Science, NC State University Libraries
Added: March 18, 2024

2024 article

Serovar-level identification of bacterial foodborne pathogens from full-length 16S rRNA gene sequencing

Grinevich, D., Harden, L., Thakur, S., & Callahan, B. (2024, February 6). (M. G. I. Langille, Ed.). MSYSTEMS, Vol. 2.

By: D. Grinevich n, L. Harden n, S. Thakur n & B. Callahan n

Ed(s): M. Langille

author keywords: serotyping; food-borne pathogens; Salmonella; Escherichia coli; 16S rRNA; long-read sequencing
TL;DR: A new computational technology is developed that allows the important foodborne pathogens Escherichia coli and Salmonella enterica to be serotyped (a subspecies level classification) from sequencing of a single-marker gene, and the 16S rRNA gene often used to surveil bacterial communities. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: February 7, 2024

2023 journal article

Detection of resistance and virulence plasmids in Campylobacter coli and Campylobacter jejuni isolated from North Carolina food animal production, 2018-2019

FOOD MICROBIOLOGY, 116.

By: D. Hull n, E. Harrel n, L. Harden n & S. Thakur n

author keywords: Antimicrobial resistance; Food -borne pathogen; Horizontal gene transfer; Transposons; Bioinformatics
TL;DR: This study highlights the extensive distribution and diversity of Campylobacter plasmids in food animal production and their role in the dissemination of biomedically important genes. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: October 2, 2023

2023 article

Draft Genome Sequences of Escherichia coli and Enterococcus faecalis Coisolated from Polymicrobial Extraintestinal Infections of Chickens and Turkeys

Walker, G. K., Harden, L., Suyemoto, M. M., Thakur, S., Jacob, M., & Borst, L. B. (2023, February 21). MICROBIOLOGY RESOURCE ANNOUNCEMENTS, Vol. 2.

By: G. Walker n, L. Harden n, M. Suyemoto n, S. Thakur n, M. Jacob n & L. Borst n

TL;DR: It is reported that draft genome sequences of 18 APEC and 18 E. faecalis strains coisolated from lesions of diseased poultry with colisepticemia are reported. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: March 20, 2023

2023 article

Draft genome sequences of 12 Escherichia coli co-isolated with Enterococcus spp. from dogs with polybacterial bacteriuria at a veterinary hospital

Walker, G. K., Harden, L., Suyemoto, M. M., Thakur, S., Jacob, M., & Borst, L. B. (2023, August 8). MICROBIOLOGY RESOURCE ANNOUNCEMENTS, Vol. 8.

By: G. Walker n, L. Harden n, M. Suyemoto n, S. Thakur n, M. Jacob n & L. Borst n

author keywords: E; coli; UPEC; canine urinary tract infection; polymicrobial infections
TL;DR: The draft genome sequences of 12 UPEC co-isolated with Enterococcus spp. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 21, 2023

2023 journal article

Uncovering changes in microbiome profiles across commercial and backyard poultry farming systems

MICROBIOLOGY SPECTRUM, 11(5).

By: M. Muyyarikkandy n, J. Parzygnat n & S. Thakur n

Contributors: A. Agunos & G. Agga

Ed(s): B. Steven

author keywords: poultry microbiome; broiler farming; relative abundance; marker taxa; temporal changes
Sources: Web Of Science, NC State University Libraries, ORCID
Added: September 24, 2023

2022 journal article

Characterization of Salmonella enterica Contamination in Pork and Poultry Meat from Sao Paulo/Brazil: Serotypes, Genotypes and Antimicrobial Resistance Profiles

PATHOGENS, 11(3).

By: V. Gomes*, L. Moreno*, A. Silva*, S. Thakur n, R. La Ragione*, A. Mather*, A. Moreno*

author keywords: Salmonella enterica; pork; poultry; serotype; antimicrobial resistance; PFGE
TL;DR: Assessment of Salmonella enterica contamination in pork and poultry meat sold at retail markets in São Paulo, Brazil shows high resistance rates to critically important antimicrobials reinforce the importance of controlling Salmonellosis in meat production chains. (via Semantic Scholar)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: March 21, 2022

2022 journal article

Evidence of sheep and abattoir environment as important reservoirs of multidrug-resistant Salmonella and extended-spectrum beta-lactamase Escherichia coli

International Journal of Food Microbiology, 363, 109516.

By: N. Atlaw n, S. Keelara n, M. Correa n, D. Foster n, W. Gebreyes*, A. Aidara-Kane*, L. Harden n, S. Thakur n, P. Fedorka-Cray n

author keywords: Salmonella; Abattoir; Sheep; Antimicrobial susceptibility; Prevalence
MeSH headings : Abattoirs; Animals; Anti-Bacterial Agents / pharmacology; Cattle; Chickens; Cross-Sectional Studies; Drug Resistance, Multiple, Bacterial; Escherichia coli / genetics; Salmonella / genetics; Sheep; Swine; beta-Lactamases / genetics
TL;DR: It is reaffirmed that sheep and their abattoir environment act as important reservoirs of AMR ESBL E. coli and MDR Salmonella in the U.S. and further studies are required to determine associated public health risks. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, ORCID
Added: January 5, 2022

2022 article

Genomic Screening of Antimicrobial Resistance Markers in UK and US Campylobacter Isolates Highlights Stability of Resistance over an 18-Year Period

Vliet, A. H. M., Thakur, S., Prada, J. M., Mehat, J. W., & La Ragione, R. M. (2022, April 11). ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, Vol. 4.

By: A. Vliet*, S. Thakur n, J. Prada*, J. Mehat* & R. La Ragione*

author keywords: antimicrobial resistance; antibiotic stewardship; Campylobacter; surveillance; quinolones; tetracycline; aminoglycosides; macrolides; whole-genome sequencing; surveillance studies
MeSH headings : Aminoglycosides; Anti-Bacterial Agents / pharmacology; Campylobacter / genetics; Campylobacter Infections / drug therapy; Campylobacter Infections / epidemiology; Campylobacter Infections / microbiology; Campylobacter coli; Campylobacter jejuni; Drug Resistance, Bacterial / genetics; Genomics; Humans; Macrolides / pharmacology; Microbial Sensitivity Tests; Multilocus Sequence Typing; Quinolones; United States / epidemiology
TL;DR: It is shown that the prevalence of AMR remains stable for Campylobacter in the UK and the US, and antimicrobial stewardship and restricted antibiotic usage may help contain further expansion ofAMR prevalence but are unlikely to reduce it in the short term. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: April 25, 2022

2022 journal article

Genomics of human and chicken Salmonella isolates in Senegal: Broilers as a source of antimicrobial resistance and potentially invasive nontyphoidal salmonellosis infections

PLOS ONE, 17(3).

By: Y. Dieye*, D. Hull n, A. Wane*, L. Harden n, C. Fall*, B. Sambe-Ba*, A. Seck*, P. Fedorka-Cray n, S. Thakur n

MeSH headings : Animals; Anti-Bacterial Agents / pharmacology; Chickens; Drug Resistance, Bacterial / genetics; Drug Resistance, Multiple, Bacterial / genetics; Gastroenteritis / microbiology; Genomics; Humans; Microbial Sensitivity Tests; Phylogeny; Salmonella; Salmonella Infections / epidemiology; Salmonella Infections / microbiology; Senegal / epidemiology
TL;DR: A whole-genome sequence analysis of 72 strains of Salmonella isolated from diarrheic human patients and chicken meat sold in multipurpose markets in Dakar, Senegal revealed frequent resistance to fluoroquinolones and the sulfamethoxazole-trimethoprim combination that are among the most used treatments for invasiveSalmonella. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: April 25, 2022

2022 journal article

Molecular characterization of multi drug resistant Escherichia coli isolates at a tertiary hospital in Abuja, Nigeria

Scientific Reports, 12(1).

By: N. Medugu*, M. Aworh*, K. Iregbu*, P. Nwajiobi-Princewill*, K. Abdulraheem*, D. Hull n, L. Harden n, P. Singh* ...

MeSH headings : Anti-Bacterial Agents / pharmacology; Anti-Bacterial Agents / therapeutic use; Drug Resistance, Multiple, Bacterial / genetics; Escherichia coli / genetics; Escherichia coli Infections / drug therapy; Escherichia coli Infections / epidemiology; Escherichia coli Proteins / genetics; Female; Humans; Male; Microbial Sensitivity Tests; Nigeria / epidemiology; Tertiary Care Centers; beta-Lactamases / genetics; beta-Lactamases / metabolism
TL;DR: The genetic diversity and MDR E. coli with the emergence of ST410 and ST101 clones is concerning because of the potential for rapid dissemination in hospitals and communities- further increasing the problems of antibiotic resistance. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: September 28, 2022

2022 journal article

Multidrug resistance and virulence genes carried by mobile genomic elements in Salmonella enterica isolated from live food animals, processed, and retail meat in North Carolina, 2018-2019

INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY, 378.

By: D. Hull n, E. Harrell n, L. Harden n & S. Thakur n

author keywords: Whole-genome sequencing; Plasmid assembly; Bioinformatics; Pathogen fitness; Food safety
MeSH headings : Animals; Anti-Bacterial Agents / pharmacology; Cattle; Drug Resistance, Multiple, Bacterial / genetics; Genomics; Humans; Meat; Microbial Sensitivity Tests; North Carolina; Plasmids; Poultry; Salmonella Infections; Salmonella enterica; Swine; Virulence / genetics; Virulence Factors / genetics
TL;DR: Plasmid-mediated virulence factors also appear to provide a fitness advantage, as the dominant S. enterica serotype Kentucky in chicken retail meat held the greatest diversity of plasmID-mediated colicin virulence genes which are often upregulated by environmental stressors and confer a competitive advantage. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 15, 2022

2022 journal article

Toward the Adoption of Loop-Mediated Isothermal Amplification for Salmonella Screening at the National Antimicrobial Resistance Monitoring System's Retail Meat Sites

FOODBORNE PATHOGENS AND DISEASE, 19(11), 758–766.

By: S. Young*, K. Domesle*, R. McDonald*, K. Lozinak*, P. Laksanalamai*, E. Harrell n, S. Thakur n, C. Kabera* ...

author keywords: antimicrobial resistance; LAMP; NARMS; Salmonella; screening; monitoring
MeSH headings : Humans; Animals; United States; Anti-Bacterial Agents / pharmacology; Drug Resistance, Bacterial / genetics; Salmonella; Meat / microbiology; Microbial Sensitivity Tests
TL;DR: A method comparison study clearly demonstrated the benefit of a rapid, robust, and highly sensitive molecular screening method in streamlining the laboratory workflow. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: May 1, 2023

2022 article

Tracking the Transmission of Antimicrobial-Resistant Non-O157 Escherichia coli and Salmonella Isolates at the Interface of Food Animals and Fresh Produce from Agriculture Operations Using Whole-Genome Sequencing

Glaize, A., Hull, D., Raymond, L., Vliet, A. H. M., Gutierrez-Rodriguez, E., & Thakur, S. (2022, August 4). FOODBORNE PATHOGENS AND DISEASE, Vol. 8.

By: A. Glaize n, D. Hull n, L. Raymond n, A. Vliet*, E. Gutierrez-Rodriguez* & S. Thakur n

author keywords: extended-spectrum beta-lactamase; phylogroups; antimicrobial resistance; enteropathogenic Escherichia coli; dairy; poultry
MeSH headings : Agriculture; Animals; Anti-Bacterial Agents / pharmacology; Anti-Bacterial Agents / therapeutic use; Drug Resistance, Bacterial / genetics; Escherichia coli; Escherichia coli Infections / veterinary; Microbial Sensitivity Tests; Poultry; Salmonella; Whole Genome Sequencing
TL;DR: This study demonstrates the prevalence of AMR and virulence genes on small-scale sustainable farms and highlights the advantage of using WGS to assess the impact of the VBZ to reduce the transmission of E. coli and Salmonella. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 29, 2022

2021 journal article

Antimicrobial resistance and interspecies gene transfer in Campylobacter coli and Campylobacter jejuni isolated from food animals, poultry processing, and retail meat in North Carolina, 2018-2019

PLOS ONE, 16(2).

By: D. Hull n, E. Harrell n, A. Vliet*, M. Correa n & S. Thakur n

MeSH headings : Animals; Anti-Bacterial Agents / pharmacology; Bacterial Proteins / genetics; Campylobacter coli / drug effects; Campylobacter coli / genetics; Campylobacter coli / isolation & purification; Campylobacter jejuni / drug effects; Campylobacter jejuni / genetics; Campylobacter jejuni / isolation & purification; Drug Resistance, Bacterial; Gene Transfer, Horizontal; Meat / microbiology; North Carolina; Poultry / microbiology
TL;DR: Evidence of C. coli and C. jejuni interspecies genomic exchange may aid pathogen adaption, lead to higher AMR and increase Campylobacter persistence in food processing is investigated to track evolving risks to public health. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: March 15, 2021

2021 article

Association between dietary vitamin D and calcium intakes and bone health outcomes in UK African-Caribbean women

PROCEEDINGS OF THE NUTRITION SOCIETY, Vol. 80.

By: R. Vearing*, S. Wilson-Barnes*, K. Charlton*, Y. Probst*, H. Ribeiro*, S. Thakur n, M. Mendes*, S. Lanham-New*, K. Hart*

Sources: Web Of Science, NC State University Libraries
Added: May 24, 2021

2021 journal article

Colonization with multidrug-resistant Enterobacteriaceae among infants: an observational study in southern Sri Lanka

ANTIMICROBIAL RESISTANCE AND INFECTION CONTROL, 10(1).

By: H. Meredith*, S. Kularatna*, K. Nagaro*, A. Nagahawatte*, C. Bodinayake*, R. Kurukulasooriya*, N. Wijesingha*, L. Harden n ...

author keywords: ESBL; CRE; Multidrug-resistant Enterobacteriaceae; Sri Lanka; Intestinal colonization
MeSH headings : Adult; Drug Resistance, Multiple, Bacterial; Enterobacteriaceae / drug effects; Enterobacteriaceae Infections / epidemiology; Female; Hospitals, Teaching; Humans; Infant, Newborn; Male; Pregnancy; Rectum / microbiology; Sri Lanka / epidemiology; Whole Genome Sequencing
TL;DR: The results suggest that a substantial proportion of infants undergo MDRE intestinal colonization within 6 weeks of birth, potentially due to postnatal rather than intranatal transmission. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: June 10, 2021

2021 journal article

Does Irrigation with Treated and Untreated Wastewater Increase Antimicrobial Resistance in Soil and Water: A Systematic Review

INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH.

By: S. Slobodiuk n, C. Niven n, G. Arthur n, S. Thakur n & A. Ercumen n

author keywords: antimicrobial resistance; resistance genes; resistant bacteria; persistent organic pollutants; wastewater irrigation; wastewater reuse; water scarcity; water insecurity; untreated municipal wastewater; treated municipal wastewater
MeSH headings : Agricultural Irrigation; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Anti-Bacterial Agents / pharmacology; Drug Resistance, Bacterial; Genes, Bacterial; Humans; Soil; Wastewater / analysis; Water
TL;DR: It is demonstrated that irrigation with untreated wastewater increases AMR in soil and call for precautionary action by field workers, their families, and consumers when untreated wastewater is used to irrigate crops. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: December 13, 2021

2021 journal article

Genetic relatedness of multidrug resistant Escherichia coli isolated from humans, chickens and poultry environments

Antimicrobial Resistance & Infection Control, 10(1).

By: M. Aworh*, J. Kwaga*, R. Hendriksen*, E. Okolocha* & S. Thakur n

author keywords: Escherichia coli; Antimicrobial resistance; Prevalence; Chicken; Multidrug resistance; Genetic relatedness; One health; Nigeria
MeSH headings : Animals; Anti-Bacterial Agents / pharmacology; Chickens / microbiology; Cross-Sectional Studies; Drug Resistance, Multiple, Bacterial / genetics; Escherichia coli / genetics; Escherichia coli / isolation & purification; Farms; Humans; Microbial Sensitivity Tests; Multilocus Sequence Typing; Nigeria; Phylogeny; Plasmids / genetics; Polymorphism, Single Nucleotide; Poultry / microbiology; Whole Genome Sequencing
TL;DR: The prevalence and genetic relatedness among MDR E. coli isolated from poultry-workers, chickens, and poultry environments in Abuja, Nigeria and the emergence of MDR E.coli with novel ST in two isolates may be plasmid-mediated. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref, ORCID
Added: April 5, 2021

2021 journal article

Genomic Characterization of a Nalidixic Acid-Resistant Salmonella Enteritidis Strain Causing Persistent Infections in Broiler Chickens

FRONTIERS IN VETERINARY SCIENCE, 8.

By: G. Walker n, M. Suyemoto n, D. Hull n, S. Gall n, F. Jimenez n, L. Chen n, S. Thakur n, R. Crespo n, L. Borst n

Contributors: G. Walker n, M. Suyemoto n, D. Hull n, S. Gall n, F. Jimenez n, L. Chen n, S. Thakur n, R. Crespo n, L. Borst n

author keywords: Salmonella Enteritidis; poultry; genomics; antimicrobial resistance; broilers
TL;DR: P phenotypic and genomic features of a virulent SE strain from persistently infected broiler flocks are reported and a workflow for SE characterization from isolate collection to genome assembly and sequence analysis is presented. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: September 27, 2021

2021 article

Global Perspective of the Vitamin D Status of African-Caribbean Populations: A Systematic Review and Meta-analysis

Vearing, R. M., Hart, K. H., Darling, A. L., Probst, Y., Olayinka, A. S., Mendis, J., … Lanham-New, S. A. (2021, July 19). EUROPEAN JOURNAL OF CLINICAL NUTRITION, Vol. 7.

By: R. Vearing*, K. Hart*, A. Darling*, Y. Probst*, A. Olayinka*, J. Mendis*, H. Ribeiro, S. Thakur n ...

MeSH headings : Diabetes Mellitus, Type 2; Dietary Supplements; Humans; Seasons; Vitamin D; Vitamin D Deficiency / epidemiology; Vitamins
TL;DR: The vitamin D status (as measured by 25(OH)D and dietary intake) of the African-Caribbean population globally is investigated by searching key databases from inception until October 2019 and sufficiency was found in African- caribbean populations at lower latitudes, however, at higher latitudes deficiency and low dietary vitamin D intake was prevalent. (via Semantic Scholar)
UN Sustainable Development Goal Categories
1. No Poverty (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 2, 2021

2021 journal article

Identification of CTX-M type ESBL E. coli from sheep and their abattoir environment using whole-genome sequencing

Pathogens, 10(11), 1480.

By: N. Atlaw n, S. Keelara n, M. Correa n, D. Foster n, W. Gebreyes*, A. Aidara-Kane*, L. Harden n, S. Thakur n, P. Fedorka-Cray n

author keywords: abattoir environment; antimicrobial resistance; E. coli; ESBL; North Carolina; sheep; whole-genome sequencing
TL;DR: This is the first comprehensive AMR and WGS report on ESBL E. coli from sheep and abattoir environments in the United States and associated AMR genes, point mutations, and plasmids. (via Semantic Scholar)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: November 16, 2021

2021 journal article

Impact of the COVID-19 pandemic on the surveillance, prevention and control of antimicrobial resistance: a global survey

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 76(11), 3045–3058.

By: S. Tomczyk*, A. Taylor*, A. Brown*, M. Kraker*, A. El-Saed*, M. Alshamrani*, R. Hendriksen*, M. Jacob n ...

MeSH headings : Anti-Bacterial Agents / pharmacology; Anti-Bacterial Agents / therapeutic use; Anti-Infective Agents; COVID-19; Drug Resistance, Bacterial; Humans; Pandemics / prevention & control; SARS-CoV-2; Surveys and Questionnaires
Sources: Web Of Science, NC State University Libraries
Added: January 18, 2022

2021 journal article

Resistome of a carbapenemase-producing novel ST232 Klebsiella michiganensis isolate from urban hospital effluent in South Africa

JOURNAL OF GLOBAL ANTIMICROBIAL RESISTANCE, 24, 321–324.

By: T. King*, S. Schmidt*, S. Thakur n, P. Fedorka-Cray n, S. Keelara n, L. Harden n, S. Essack*

author keywords: Klebsiella michiganensis; Genome; Carbapenemase; Hospital effluent; South Africa
MeSH headings : Bacterial Proteins; Drug Resistance, Bacterial / genetics; Hospitals, Urban; Klebsiella / drug effects; Klebsiella / genetics; South Africa; beta-Lactamases
TL;DR: This study represents the first report of a blaOXA-181 carbapenemase-producing K. michiganensis isolate from hospital effluent in South Africa and presents a potential risk to informal communities that may use contaminated surface water domestically. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: April 26, 2021

2021 journal article

The effect of vegetation barriers at reducing the transmission of Salmonella and Escherichia coli from animal operations to fresh produce

INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY, 347.

By: A. Glaize n, M. Young n, L. Harden n, E. Gutierrez-Rodriguez* & S. Thakur n

author keywords: Seasonality; Repetitive PCR; Dairy; Poultry; Distance; Wind
MeSH headings : Animals; Cattle; Dairying; Escherichia coli / growth & development; Escherichia coli / isolation & purification; Escherichia coli Infections / transmission; Escherichia coli Infections / veterinary; Farms; Feces / microbiology; Lettuce / microbiology; Solanum lycopersicum / microbiology; Poultry / microbiology; Salmonella / growth & development; Salmonella / isolation & purification; Salmonella Infections, Animal / transmission
TL;DR: Data analysis suggests that the VB is an effective tool at reducing the transmission of E. coli and Salmonella from animal farms to fresh produce fields, and recommends the need for more effective bioremediation and prevention control measures to use in conjunction with VBs to reduce pathogen transmission. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: June 10, 2021

2021 journal article

Ultra-accurate microbial amplicon sequencing with synthetic long reads

MICROBIOME, 9(1).

By: B. Callahan n, D. Grinevich n, S. Thakur n, M. Balamotis & T. Ben Yehezkel

author keywords: Synthetic long reads; Amplicon sequencing; Metagenomics; Long-read sequencing
MeSH headings : High-Throughput Nucleotide Sequencing; Metagenome; Microbiota / genetics; RNA, Ribosomal, 16S / genetics; Sequence Analysis, DNA
TL;DR: L loopSeq full-length 16S rRNA reads could accurately classify organisms down to the species level in rinsate from retail meat samples, and could differentiate strains within species identified by the CDC as potential foodborne pathogens. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: June 6, 2021

2020 journal article

Antimicrobial resistance and virulence factors profile of Salmonella spp. and Escherichia coli isolated from different environments exposed to anthropogenic activity

JOURNAL OF GLOBAL ANTIMICROBIAL RESISTANCE, 22, 578–583.

By: M. Balbin n, D. Hull n, C. Guest*, L. Nichols n, R. Dunn n & S. Thakur n

author keywords: Anthropogenic areas; Whole-genome sequencing; FosA7 gene; pHN7A8 (F33:A-:B-plasmid)
TL;DR: The presence of these determinants in different anthropogenic areas suggests the need to conduct longitudinal studies for comparing the profile of pathogens across different environments and the detection of AMR determinants and virulence factors in these bacteria is significant in understanding the occurrence and even the development ofAMR. (via Semantic Scholar)
UN Sustainable Development Goal Categories
11. Sustainable Cities and Communities (OpenAlex)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: October 12, 2020

2020 journal article

Class 1 integron-borne cassettes harboring blaCARB-2 gene in multidrug-resistant and virulent Salmonella Typhimurium ST19 strains recovered from clinical human stool samples, United States

PLOS ONE, 15(10), e0240978.

By: D. Monte n, F. Sellera*, R. Lopes*, S. Keelara n, M. Landgraf*, S. Greene, P. Fedorka-Cray n, S. Thakur n

Ed(s): I. Karunasagar

MeSH headings : Anti-Bacterial Agents / pharmacology; Drug Resistance, Multiple, Bacterial; Genome, Bacterial; Humans; Integrons; Microbial Sensitivity Tests; Phylogeny; Plasmids / genetics; Salmonella Infections / microbiology; Salmonella typhimurium / classification; Salmonella typhimurium / genetics; Salmonella typhimurium / isolation & purification; Salmonella typhimurium / pathogenicity; United States; Virulence Factors / genetics; Whole Genome Sequencing; beta-Lactamases / genetics
TL;DR: Overall, S. Typhimurium strains displayed multidrug-resistant profile, being resistance to critically and highly important antimicrobials including ampicillin, ticarcillin/clavulanic acid, streptomycin and sulfisoxazole, chloramphenicol, tetracycline, respectively. (via Semantic Scholar)
Source: ORCID
Added: November 1, 2020

2020 article

Future perspectives in addressing the global issue of vitamin D deficiency

Mendes, M. M., Charlton, K., Thakur, S., Ribeiro, H., & Lanham-New, S. A. (2020, May). PROCEEDINGS OF THE NUTRITION SOCIETY, Vol. 79, pp. 246–251.

By: M. Mendes*, K. Charlton*, S. Thakur n, H. Ribeiro* & S. Lanham-New*

author keywords: Vitamin D; Deficiency; Global; Future perspectives
MeSH headings : Biological Variation, Population; Dietary Supplements; Global Health; Humans; Nutritional Status; Recommended Dietary Allowances; Vitamin D / administration & dosage; Vitamin D / analogs & derivatives; Vitamin D / blood; Vitamin D / physiology; Vitamin D Deficiency / diagnosis; Vitamin D Deficiency / epidemiology
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: April 27, 2020

2020 journal article

International lineages of Salmonella enterica serovars isolated from chicken farms, Wakiso District, Uganda

PLOS ONE, 15(1).

By: T. Ball n, D. Monte*, A. Aidara-Kane*, J. Matheu*, H. Ru n, S. Thakur n, F. Ejobi*, P. Fedorka-Cray n

MeSH headings : Animals; Anti-Bacterial Agents / classification; Anti-Bacterial Agents / pharmacology; Chickens / microbiology; Drug Resistance, Multiple, Bacterial / genetics; Farms; Genes, Bacterial; Humans; Immunologic Surveillance; Plasmids / chemistry; Plasmids / metabolism; Poultry Diseases / epidemiology; Poultry Diseases / microbiology; Poultry Diseases / transmission; Prevalence; Replicon; Salmonella Infections / epidemiology; Salmonella Infections / microbiology; Salmonella Infections / transmission; Salmonella enterica / drug effects; Salmonella enterica / genetics; Salmonella enterica / isolation & purification; Seasons; Uganda / epidemiology; Whole Genome Sequencing
TL;DR: It is concluded that MDR Salmonella highlights the risks posed to the animals, environment, and humans for infection and implementing a robust integrated surveillance system in Uganda will help monitor MDR to help control infectious threats. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: June 15, 2020

2020 journal article

Molecular Epidemiology of Infectious Zoonotic and Livestock Diseases

MICROBIOLOGY SPECTRUM, 8(2).

By: W. Gebreyes*, D. Jackwood*, C. Bruno De Oliveira*, C. Lee*, A. Hoet* & S. Thakur n

MeSH headings : Animals; Campylobacter; Clostridioides difficile / genetics; Drug Resistance, Multiple, Bacterial / genetics; Farms; Genotyping Techniques / methods; Hospitals, Animal; Humans; Livestock / microbiology; Livestock / virology; Methicillin-Resistant Staphylococcus aureus / genetics; Molecular Epidemiology / methods; Salmonella / genetics; Virus Diseases / veterinary; Virus Diseases / virology; Zoonoses / microbiology; Zoonoses / virology
TL;DR: In recent years, whole-genome-sequence-based approaches have been increasingly used for molecular epidemiology of diseases at the interface of humans, animals, and the environment. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: April 14, 2020

2020 journal article

The role ofEnterococcus faecalisduring co-infection with avian pathogenicEscherichia coliin avian colibacillosis

AVIAN PATHOLOGY, 49(6), 589–599.

By: G. Walker n, M. Suyemoto n, S. Gall n, L. Chen n, S. Thakur n & L. Borst n

author keywords: Colibacillosis; Enterococcus; E; coli; co-infection; antimicrobial resistance; broiler; turkey
MeSH headings : Animals; Chick Embryo; Chickens / microbiology; Coinfection / veterinary; Enterococcus faecalis / physiology; Escherichia coli / physiology; Escherichia coli Infections / microbiology; Escherichia coli Infections / pathology; Escherichia coli Infections / veterinary; Female; Gram-Positive Bacterial Infections / microbiology; Gram-Positive Bacterial Infections / pathology; Gram-Positive Bacterial Infections / veterinary; Phenotype; Poultry Diseases / epidemiology; Poultry Diseases / microbiology; Poultry Diseases / pathology; Virulence
TL;DR: Enterococcus is frequently co-isolated with avian pathogenic E. coli from poultry with colibacillosis, and Enterococcus faecalis (EF) enhances survival of APEC in iron restricted conditions and increases APEC virulence in broiler embryos. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: September 28, 2020

2020 journal article

Transmission of antimicrobial resistant non-O157 Escherichia coli at the interface of animal-fresh produce in sustainable farming environments

International Journal of Food Microbiology, 319, 108472.

By: A. Glaize n, E. Gutierrez-Rodriguez n, I. Hanning*, S. Díaz-Sánchez*, C. Gunter n, A. van Vliet*, W. Watson n, S. Thakur n

author keywords: Pathogen transmission; Sustainable production systems; Antimicrobial resistance; Phylotyping; Non-O157 E. coli
MeSH headings : Ampicillin / pharmacology; Animals; Anti-Bacterial Agents / pharmacology; Enterotoxigenic Escherichia coli / drug effects; Enterotoxigenic Escherichia coli / genetics; Enterotoxigenic Escherichia coli / isolation & purification; Escherichia coli Infections / microbiology; Escherichia coli Infections / transmission; Farms; Foodborne Diseases / microbiology; Genome, Bacterial / genetics; Manure / microbiology; Microbial Sensitivity Tests; Serogroup; Streptomycin / pharmacology; Sulfisoxazole / pharmacology; Vegetables / microbiology
TL;DR: The results of this study show the potential of AMR E. coli transmission between animal feeding operations and fresh produce, and more studies are recommended to study this interaction and prevent dissemination in sustainable farming systems. (via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: July 7, 2020

2019 journal article

Endemic fluoroquinolone-resistant Salmonella enterica serovar Kentucky ST198 in northern India

MICROBIAL GENOMICS, 5(7).

By: J. Mahindroo*, D. Thanh*, T. Nguyen*, B. Mohan*, S. Thakur n, S. Baker*, N. Taneja*

author keywords: non-typhoidal Salmonella; fluoroquinolone; antimicrobial resistance; whole-genome sequencing; India
MeSH headings : Animals; Anti-Bacterial Agents / pharmacology; Anti-Bacterial Agents / therapeutic use; Ciprofloxacin / pharmacology; Ciprofloxacin / therapeutic use; DNA, Bacterial / genetics; Drug Resistance, Bacterial; Humans; India / epidemiology; Phylogeny; Salmonella Infections, Animal / drug therapy; Salmonella Infections, Animal / epidemiology; Salmonella Infections, Animal / microbiology; Salmonella enterica / classification; Salmonella enterica / drug effects; Salmonella enterica / genetics; Salmonella enterica / isolation & purification; Serogroup; Whole Genome Sequencing
TL;DR: This is, to the best of the knowledge, the first study reporting the identification of this epidemic clone in India and South Asia. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 19, 2019

2019 journal article

First Genome Sequence of Brucella abortus Biovar 3 Strain BAU21/S4023, Isolated from a Dairy Cow in Bangladesh

MICROBIOLOGY RESOURCE ANNOUNCEMENTS, 8(24).

TL;DR: The genome sequence of Brucella abortus biovar 3 strain BAU21/S4023, isolated from a dairy cow that suffered an abortion in Savar, Dhaka, Bangladesh, is reported. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: July 1, 2019

2019 article

First Genome Sequence of Brucella abortus Biovar 3 Strain BAU21/S4023, Isolated from a Dairy Cow in Bangladesh (vol 8, e00446-19, 2019)

Islam, M. S., El Zowalaty, M. E., Vliet, A. H. M., Thakur, S., Khatun, M. M., Saha, S., … Islam, M. A. (2019, July). MICROBIOLOGY RESOURCE ANNOUNCEMENTS, Vol. 8.

UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 5, 2019

2019 book

Food safety in Poultry meat production

(1st ed.). Springer US.

By: K. Venkitanarayanan, S. Thakur & S. Ricke

Source: NC State University Libraries
Added: February 21, 2019

2019 journal article

Genomic Features of High-Priority Salmonella enterica Serovars Circulating in the Food Production Chain, Brazil, 2000-2016

SCIENTIFIC REPORTS, 9.

By: D. Monte n, N. Lincopan*, H. Berman n, L. Cerdeira*, S. Keelara n, S. Thakur n, P. Fedorka-Cray n, M. Landgraf*

MeSH headings : Agriculture; Animals; Brazil; Drug Resistance, Multiple, Bacterial / genetics; Poultry; Salmonella Infections, Animal / diagnosis; Salmonella Infections, Animal / genetics; Salmonella enterica / isolation & purification; Serogroup; Swine
TL;DR: Ocurrence and persistence of international lineages of S. enterica serovars in food production chain is supported by conserved genomes and wide virulome and resistome, which revealed presence of qnrE1 (identified for the first time in S. Typhimurium from food chain). (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 12, 2019

2019 journal article

Multidrug- and colistin-resistant Salmonella enterica 4,[5],12:i:- sequence type 34 carrying the mcr-3.1 gene on the IncHI2 plasmid recovered from a human

Journal of Medical Microbiology, 68(7), 986–990.

By: D. Monte n, V. Nelson n, L. Cerdeira*, S. Keelara n, S. Greene, D. Griffin, S. Rath, R. Hall ...

author keywords: IncHI2; MCR-3.1; Salmonella enterica 4; [5]; 12:i:-; United States
MeSH headings : Anti-Bacterial Agents / pharmacology; Bacterial Proteins / genetics; Bacterial Proteins / metabolism; China; Drug Resistance, Multiple, Bacterial / genetics; Humans; Plasmids / genetics; Salmonella enterica / drug effects; Salmonella enterica / genetics; Salmonella enterica / isolation & purification; Transferases (Other Substituted Phosphate Groups) / genetics; Transferases (Other Substituted Phosphate Groups) / metabolism; Travel
TL;DR: Genomic analysis revealed the presence of the mcr-3.1 gene located in the globally disseminated IncHI2 plasmid, highlighting the intercontinental dissemination of the colistin-resistant S. enterica 4, [5],12:i:- ST34 pandemic clone. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: July 22, 2019

2019 article

Multidrug- and colistin-resistant Salmonella enterica 4,[5],12:i:- sequence type 34 carrying the mcr-3.1 gene on the IncHI2 plasmid recovered from a human (vol 68, pg 986, 2019)

Monte, D. F., Nelson, V., Cerdeira, L., Keelara, S., Greene, S., Griffin, D., … Thakur, S. (2019, November). JOURNAL OF MEDICAL MICROBIOLOGY, Vol. 68, pp. 1694–1694.

By: D. Monte n, V. Nelson n, L. Cerdeira*, S. Keelara n, S. Greene, D. Griffin, S. Rath, R. Hall ...

UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: November 25, 2019

2019 journal article

Phenotypic and Genotypic Characterization of Escherichia coli and Salmonella enterica from Dairy Cattle Farms in the Wakiso District, Uganda: A Cross-Sectional Study

Foodborne Pathogens and Disease, 16(1), 54–59.

By: T. Ball n, D. Monte*, A. Aidara-Kane*, J. Matheu-Alvarez*, H. Ru n, S. Thakur n, J. Horovitz n, F. Ejobi* ...

author keywords: antimicrobial resistance; ESBL; E; coli; Salmonella enterica; Uganda
MeSH headings : Animals; Anti-Infective Agents / pharmacology; Cattle; Cross-Sectional Studies; Dairying; Drug Resistance, Multiple, Bacterial; Escherichia coli / enzymology; Escherichia coli / genetics; Escherichia coli / isolation & purification; Escherichia coli Infections / epidemiology; Escherichia coli Infections / microbiology; Escherichia coli Infections / veterinary; Farms; Feces / microbiology; Female; Pilot Projects; Plasmids / genetics; Quinolones / pharmacology; Salmonella Infections, Animal / epidemiology; Salmonella Infections, Animal / microbiology; Salmonella enterica / enzymology; Salmonella enterica / genetics; Salmonella enterica / isolation & purification; Uganda / epidemiology; beta-Lactamases / genetics
TL;DR: It is concluded that the presence of globally disseminated E. coli carrying blaCTX-M-15 and bla CTX- M-27 warrants further study to prevent further spread, and can be used as a baseline for implementation of a more robust national integrated surveillance system throughout Uganda. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Crossref, NC State University Libraries
Added: February 18, 2019

2019 journal article

Prevalence and risk factors for multi-drug resistant Escherichia coli among poultry workers in the Federal Capital Territory, Abuja, Nigeria

PLOS ONE, 14(11), e0225379.

By: M. Aworh*, J. Kwaga*, E. Okolocha*, N. Mba & S. Thakur n

Contributors: M. Aworh*, J. Kwaga*, E. Okolocha*, N. Mba & S. Thakur n

Ed(s): G. Woźniakowski

MeSH headings : Adolescent; Adult; Animals; Cross-Sectional Studies; Escherichia coli / drug effects; Escherichia coli Infections / epidemiology; Escherichia coli Infections / microbiology; Female; Humans; Male; Nigeria / epidemiology; Poultry Diseases / epidemiology; Prevalence; Risk Factors; Surveys and Questionnaires; Young Adult
TL;DR: Prevalence of resistant E. coli was highest among farm-workers and associated with older farms/markets, occupational exposure of over 10 years and poor hygienic measures. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, ORCID, Crossref
Added: June 8, 2020

2019 journal article

The Mandate for a Global “One Health” Approach to Antimicrobial Resistance Surveillance

The American Journal of Tropical Medicine and Hygiene, 1.

By: S. Thakur n & G. Gray*

MeSH headings : Animals; Anti-Bacterial Agents; Drug Resistance, Bacterial / drug effects; Ecuador; Escherichia coli / drug effects; Global Health; Poultry; Prevalence; Weights and Measures; beta-Lactamases
TL;DR: The researchers investigated the prevalence of CTX-M extended-spectrum beta-lactamases in chickens from small-scale poultry farms and in children living on the farms in rural Ecuador, and reported a shared evolutionary history between chicken and human samples. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: February 18, 2019

2018 chapter

Antibiotic Usage in Poultry Production and Antimicrobial Resistant Salmonella in Poultry

In K. Venkitanarayanan, S. Thakur, & S. C. Ricke (Eds.), Food safety in Poultry meat production (p. 301). Publisher: Springer US.

By: D. Kumar, S. Pornsukarom & S. Thakur

Ed(s): K. Venkitanarayanan, S. Thakur & S. Ricke

Source: NC State University Libraries
Added: March 9, 2019

2018 journal article

Environmental Dissemination of Multidrug Methicillin-Resistant Staphylococcus sciuri After Application of Manure from Commercial Swine Production Systems

FOODBORNE PATHOGENS AND DISEASE, 15(4), 210–217.

By: D. Kumar*, S. Pornsukarom n, G. Sivaraman* & S. Thakur n

author keywords: swine; manure; soil; antimicrobial resistance; environment
MeSH headings : Animals; Anti-Bacterial Agents / pharmacology; Drug Resistance, Multiple, Bacterial / genetics; Erythromycin / pharmacology; Genes, Bacterial; Genotyping Techniques; Iowa; Manure / microbiology; Methicillin-Resistant Staphylococcus aureus / genetics; Methicillin-Resistant Staphylococcus aureus / isolation & purification; Microbial Sensitivity Tests; North Carolina; Soil Microbiology; Swine; Tetracycline / pharmacology
TL;DR: Overall, this study identifies swine manure as an important reservoir of MDR-MRSS and highlights its dissemination in the environment upon spreading of manure. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2018 journal article

First report of mcr-1-harboring Salmonella enterica serovar Schwarzengrund isolated from poultry meat in Brazil

Diagnostic Microbiology and Infectious Disease, 11.

By: L. Moreno*, V. Gomes*, J. Moreira*, C. de Oliveira*, B. Peres*, A. Silva*, S. Thakur n, R. La Ragione*, A. Moreno*

author keywords: Salmonella enterica; Schwarzengrund; Poultry; Colistin resistance; Plasmid
MeSH headings : Animals; Anti-Bacterial Agents / pharmacology; Brazil; Colistin / pharmacology; Drug Resistance, Bacterial; Escherichia coli Proteins / genetics; Genotype; Meat / microbiology; Microbial Sensitivity Tests; Multilocus Sequence Typing; Plasmids / analysis; Poultry; Salmonella enterica / drug effects; Salmonella enterica / genetics; Salmonella enterica / isolation & purification; Serogroup; Whole Genome Sequencing
TL;DR: Brazilian poultry meat samples were screened for colistin-resistant Salmonella enterica enterica and whole-genome analysis determined the serovar to be Schwarzengrund, ST96, harboring the IncX4 plasmid. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Crossref, NC State University Libraries
Added: February 18, 2019

2018 journal article

Molecular Characterization of Salmonella spp. from Cattle and Chicken Farms in Uganda

Online Journal of Public Health Informatics, 10(1), 148.

By: T. Ball, P. Cray, J. Horovitz & S. Thakur

Source: NC State University Libraries
Added: February 18, 2019

2018 journal article

Molecular Tools To Study Preharvest Food Safety Challenges

Microbiology Spectrum, 6(1), 361–382.

By: D. Kumar* & S. Thakur n

Ed(s): S. Thakur n & K. Kniel

MeSH headings : Bacteria / classification; Bacteria / genetics; Bacteria / isolation & purification; Food Contamination / analysis; Food Contamination / prevention & control; Food Microbiology / methods; Food Safety / methods; Foodborne Diseases / prevention & control; Humans; Meat / microbiology; Molecular Typing / methods; Oligonucleotide Array Sequence Analysis / methods; Polymerase Chain Reaction / methods; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / methods
TL;DR: The molecular methods available for detection and molecular typing of bacterial foodborne pathogens at the farm are discussed, including conventional techniques such as endpoint PCR, real-time PCR, DNA microarray, and more advanced methods such as matrix-assisted layer desorption ionization-time of flight mass spectrometry and whole-genome sequencing. (via Semantic Scholar)
Sources: NC State University Libraries, Crossref, NC State University Libraries
Added: February 21, 2019

2018 journal article

Molecular tools to study preharvest food safety challenges

Microbiology Spectrum, 6(1).

By: D. Kumar & S. Thakur

Source: NC State University Libraries
Added: August 6, 2018

2018 book

Preharvest Food Safety

(T. & K., Eds.).

By: N. Libraries

Ed(s): Thakur & Kniel

UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: February 18, 2019

2018 book

Preharvest Food Safety

American Society for Microbiology.

By: S. Thakur & K. Kniel

Source: NC State University Libraries
Added: September 11, 2019

2018 book

Preharvest food safety

Washington, DC: ASM Press.

Siddhartha Thakur

Ed(s): S. Thakur & K. Kniel

Source: NC State University Libraries
Added: February 5, 2022

2018 journal article

The role of citizen science in addressing grand challenges in food and agriculture research

Proceedings of the Royal Society B: Biological Sciences, 285(1891), 20181977.

By: S. Ryan*, N. Adamson*, A. Aktipis*, L. Andersen*, R. Austin*, L. Barnes, M. Beasley, K. Bedell* ...

Contributors: S. Ryan*, N. Adamson*, A. Aktipis*, L. Andersen*, R. Austin*, L. Barnes, M. Beasley, K. Bedell* ...

author keywords: citizen science; agriculture; grand challenges; sustainable development goals; extension; food science
MeSH headings : Agriculture / standards; Agriculture / trends; Community Participation; Food; Research / standards; Research / trends; United States
TL;DR: It is argued there is no better time to foster greater collaboration between these fields given the trend of shrinking Extension programmes, the increasing need to apply innovative solutions to address rising demands on agricultural systems, and the exponential growth of the field of citizen science. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
13. Climate Action (Web of Science)
15. Life on Land (Web of Science)
Sources: Crossref, NC State University Libraries, ORCID
Added: February 18, 2019

2018 journal article

Understanding the Complexities of Food Safety Using a “One Health” Approach

Microbiology Spectrum, 6(1).

By: K. Kniel*, D. Kumar* & S. Thakur n

MeSH headings : Animal Husbandry / methods; Animals; Communicable Disease Control / methods; Communicable Diseases / transmission; Environmental Health / methods; Food Safety / methods; Humans; One Health; Zoonoses / prevention & control; Zoonoses / transmission
TL;DR: The recent explosion of Zika virus around the globe renewed the need for assessing transmissible diseases through the eyes of One Health, and an ever-growing trade and global commerce system mixed with the authors' incessant desire for food products during the whole year makes it all the more important to take a global view through the One Health lens to solve these growing challenges. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Crossref, NC State University Libraries, NC State University Libraries
Added: August 6, 2018

2018 journal article

Whole genome sequencing analysis of multiple Salmonella serovars provides insights into phylogenetic relatedness, antimicrobial resistance, and virulence markers across humans, food animals and agriculture environmental sources

BMC GENOMICS, 19.

By: S. Pornsukarom*, A. Vliet* & S. Thakur n

author keywords: Salmonella; WGS; Core genome; SNP; FFP; Antimicrobial resistance; Virulence gene; Plasmid; Human; Swine; Poultry; Environment
MeSH headings : Agriculture; Animals; Anti-Bacterial Agents / pharmacology; Chickens; Drug Resistance, Bacterial; Genome, Bacterial; Genotype; Humans; Phylogeny; Polymorphism, Single Nucleotide; Salmonella / classification; Salmonella / genetics; Salmonella / isolation & purification; Salmonella / pathogenicity; Salmonella Infections / microbiology; Serogroup; Swine; Virulence; Whole Genome Sequencing / methods
TL;DR: The clinical isolates clustered closely with animal and environmental isolates, suggesting that animals and environment are potential sources for dissemination of AMR and virulence genes between Salmonella serovars. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: November 26, 2018

2017 journal article

Horizontal Dissemination of Antimicrobial Resistance Determinants in Multiple Salmonella Serotypes following Isolation from the Commercial Swine Operation Environment after Manure Application

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 83(20).

By: S. Pornsukarom n & S. Thakur n

author keywords: Salmonella; plasmid; antimicrobial resistance; horizontal gene transfer; environment; environmental microbiology; swine farm
MeSH headings : Animals; Anti-Bacterial Agents / pharmacology; Conjugation, Genetic; Drug Resistance, Bacterial; Gene Transfer, Horizontal; Integrons; Manure / microbiology; Microbial Sensitivity Tests; Phylogeny; Plasmids / genetics; Plasmids / metabolism; Salmonella Infections, Animal / microbiology; Salmonella enterica / drug effects; Salmonella enterica / genetics; Salmonella enterica / isolation & purification; Salmonella enterica / metabolism; Serogroup; Swine; Swine Diseases / microbiology
TL;DR: Significant evidence is provided on the importance of horizontal dissemination of resistance determinants through plasmids of multiple Salmonella serotypes distributed across commercial swine farms after manure application and the deposition of manure generated in swine production systems into the environment is identified as a potential source of AMR dissemination. (via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2017 chapter

Molecular epidemiology of zoonotic and livestock diseases

In L. W. Riley (Ed.), Molecular Epidemiology of Infectious Diseases, Principles and Practices (2nd ed.). ASM Publications.

By: W. Gebreyes, D. Jackwood, C. Lee, A. Hoet, S. Thakur & L. Riley

Ed(s): L. Riley

Source: NC State University Libraries
Added: February 21, 2019

2017 journal article

Multilaboratory Survey To Evaluate Salmonella Prevalence in Diarrheic and Nondiarrheic Dogs and Cats in the United States between 2012 and 2014

Journal of Clinical Microbiology, 55(5), 1350–1368.

By: R. Reimschuessel*, M. Grabenstein*, J. Guag*, S. Nemser*, K. Song*, J. Qiu*, K. Clothier*, B. Byrne* ...

Ed(s): B. Fenwick

author keywords: Salmonella; diarrhea; fecal organisms; pets; WGS
MeSH headings : Animal Feed / microbiology; Animals; Anti-Bacterial Agents / therapeutic use; Cats; Cross-Sectional Studies; Dogs; Feces / microbiology; Female; Foodborne Diseases / epidemiology; Foodborne Diseases / microbiology; Foodborne Diseases / veterinary; Male; Microbial Sensitivity Tests; Salmonella / drug effects; Salmonella / isolation & purification; Salmonella Infections, Animal / drug therapy; Salmonella Infections, Animal / epidemiology; Salmonella Infections, Animal / microbiology; United States
TL;DR: An overall decline in prevalence of Salmonella-positive dogs and cats in the United States over the last decades is suggested and consumption of raw food is identified as a major risk factor forSalmonella infection. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2016 journal article

Assessing the Impact of Manure Application in Commercial Swine Farms on the Transmission of Antimicrobial Resistant Salmonella in the Environment

PLOS ONE, 11(10).

By: S. Pornsukarom n & S. Thakur n

MeSH headings : Animals; Anti-Bacterial Agents / pharmacology; Drug Resistance, Multiple, Bacterial / drug effects; Electrophoresis, Gel, Pulsed-Field; Environment; Manure / microbiology; Microbial Sensitivity Tests; Phylogeny; Salmonella / classification; Salmonella / drug effects; Salmonella / isolation & purification; Salmonella Infections, Animal / microbiology; Salmonella Infections, Animal / pathology; Salmonella Infections, Animal / transmission; Serogroup; Streptomycin / pharmacology; Sulfisoxazole / pharmacology; Swine; Swine Diseases / microbiology; Swine Diseases / pathology; Tetracycline / pharmacology
TL;DR: Genotypic characterization by pulse field gel electrophoresis revealed clonally related Salmonella in both manure and soil at multiple time points in the positive farms, highlighting the potential role of swine manure application in the dissemination and persistence of antimicrobial resistant Salmoneella in the environment. (via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2016 journal article

Biofilm Formation by Environmental Isolates of Salmonella and Their Sensitivity to Natural Antimicrobials

FOODBORNE PATHOGENS AND DISEASE, 13(9), 509–516.

By: S. Keelara n, S. Thakur n & J. Patel*

MeSH headings : Acrolein / analogs & derivatives; Acrolein / pharmacology; Animals; Anti-Bacterial Agents / pharmacology; Biofilms / drug effects; Biofilms / growth & development; Environmental Microbiology; Microbial Sensitivity Tests; Microscopy, Electron, Scanning; North Carolina; Oils, Volatile / pharmacology; Salmonella enterica / classification; Salmonella enterica / isolation & purification; Salmonella enterica / physiology; Swine / microbiology
TL;DR: Cinnamaldehyde and sporran at 1000 ppm significantly reduced Salmonella in biofilms and the bactericidal effect of these antimicrobials increased with their concentrations. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2016 journal article

Cronobacter sakazakii - An unrecognised food borne pathogen, India

International Journal of Infectious Diseases, 45, 182.

By: J. Mahindroo*, I. Shyam*, B. Mohan*, S. Thakur n & N. Taneja*

UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: February 18, 2019

2016 chapter

Phenotypic Sub typing of Foodborne Pathogens

In S. Brul, P. M. Fratamico, & T. A. McMeekin (Eds.), Tracking Pathogens in the Food Chain. Woodhead Publishing Limited.

By: W. Gebereys & S. Thakur

Ed(s): S. Brul, P. Fratamico & T. McMeekin

Source: NC State University Libraries
Added: September 8, 2019

2015 journal article

Early-life dietary spray-dried plasma influences immunological and intestinal injury responses to later-life Salmonella typhimurium challenge

BRITISH JOURNAL OF NUTRITION, 113(5), 783–793.

By: P. Boyer n, . S. D'Costa, L. Edwards n, M. Milloway n, E. Susick n, L. Borst n, S. Thakur n, J. Campbell ...

author keywords: Spray-dried plasma; Early-life nutrition; Salmonella typhimurium; Intestinal inflammation; Mucosal immunity; Intestinal permeability; Weaning
MeSH headings : Animals; Biomarkers / blood; Biomarkers / metabolism; Blood Proteins / administration & dosage; Blood Proteins / therapeutic use; Crosses, Genetic; Cytokines / blood; Cytokines / metabolism; Diet / adverse effects; Diet / veterinary; Energy Intake; Enterocolitis / immunology; Enterocolitis / microbiology; Enterocolitis / prevention & control; Enterocolitis / veterinary; Feces / microbiology; Female; Ileum / immunology; Ileum / metabolism; Ileum / microbiology; Ileum / pathology; Immunity, Mucosal; Immunotherapy / adverse effects; Immunotherapy / veterinary; Intestinal Mucosa / immunology; Intestinal Mucosa / metabolism; Intestinal Mucosa / microbiology; Intestinal Mucosa / pathology; Male; Salmonella Infections, Animal / immunology; Salmonella Infections, Animal / metabolism; Salmonella Infections, Animal / microbiology; Salmonella Infections, Animal / prevention & control; Salmonella typhimurium / growth & development; Salmonella typhimurium / immunology; Salmonella typhimurium / isolation & purification; Sus scrofa; Swine; Swine Diseases / immunology; Swine Diseases / metabolism; Swine Diseases / microbiology; Swine Diseases / prevention & control; Weaning; Weight Gain
TL;DR: Results indicate that inclusion of SDP in PW diets can have an influence on subsequent immunological and intestinal injury responses induced by later-life S. typhimurium challenge. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2014 journal article

Comparative phenotypic and genotypic characterization of temporally related nontyphoidal salmonella isolated from human clinical cases, pigs, and the environment in North Carolina

Foodborne Pathogens and Disease, 11(2), 156–164.

By: S. Keelara n, H. Scott*, W. Morrow n, C. Hartley*, D. Griffin*, W. Gebreyes*, S. Thakur n

MeSH headings : Animals; Anti-Bacterial Agents / pharmacology; Bacterial Proteins / genetics; Cephalosporins / pharmacology; Drug Resistance, Multiple, Bacterial; Electrophoresis, Gel, Pulsed-Field; Genotype; Humans; Integrons; Microbial Sensitivity Tests; North Carolina; Phenotype; Salmonella / classification; Salmonella / genetics; Salmonella / isolation & purification; Swine / microbiology; beta-Lactamases / genetics
TL;DR: Overall, Salmonella isolates exhibited the highest frequency of resistance to tetracycline, followed by sulfisoxazole and streptomycin, and 16 different antimicrobial resistance genes were identified in all the β-lactam- and cephalosporin-resistant Salmoneella isolates from humans, pigs, and the environment. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: NC State University Libraries, NC State University Libraries
Added: August 6, 2018

2014 journal article

Dissemination of plasmid-encoded AmpC beta-lactamases in antimicrobial resistant Salmonella serotypes originating from humans, pigs and the swine environment

VETERINARY MICROBIOLOGY, 173(1-2), 76–83.

By: S. Keelara n & S. Thakur n

author keywords: Salmonella; Plasmids; Antimicrobial resistance and pigs; Conjugation
MeSH headings : Animals; Anti-Bacterial Agents / pharmacology; Bacterial Proteins / genetics; Bacterial Proteins / isolation & purification; Bacterial Typing Techniques; Blotting, Southern; Conjugation, Genetic; Humans; Microbial Sensitivity Tests; North Carolina / epidemiology; Plasmids; Polymerase Chain Reaction; Replicon; Salmonella / drug effects; Salmonella / enzymology; Salmonella / genetics; Salmonella Infections, Animal / drug therapy; Salmonella Infections, Animal / epidemiology; Salmonella Infections, Animal / microbiology; Salmonella Infections, Animal / transmission; Soil Microbiology; Swine / microbiology; Water Microbiology; beta-Lactamases / genetics; beta-Lactamases / isolation & purification
TL;DR: It is demonstrated likely horizontal inter-serovar exchange of plasmid-encoding AmpC β-lactamases resistance among MDR Salmonella serotypes isolated from pigs, swine farm environment and clinical human cases. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2013 journal article

Co-occurrence and Environmental Distribution of Campylobacter and Salmonella in Broiler Flocks

Research in Veterinary Science, 94, 33–42.

By: S. Thakur, J. Brake, S. Keelara, M. Zou & E. Susick

Source: NC State University Libraries
Added: February 18, 2019

2013 journal article

Farm and environmental distribution of Campylobacter and Salmonella in broiler flocks

RESEARCH IN VETERINARY SCIENCE, 94(1), 33–42.

By: S. Thakur n, J. Brake n, S. Keelara n, M. Zou* & E. Susick n

author keywords: Campylobacter; Salmonella; Broiler; Antimicrobial resistance; Genotyping; Transmission
MeSH headings : Animal Husbandry; Animals; Campylobacter Infections / microbiology; Campylobacter jejuni / drug effects; Chickens / microbiology; Drug Resistance, Microbial; Environmental Microbiology; Feces / microbiology; Housing, Animal; Microbial Sensitivity Tests / veterinary; Poultry Diseases / microbiology; Salmonella Infections, Animal / microbiology; Salmonella typhimurium / drug effects; Streptomycin / pharmacology; Tetracycline / pharmacology
TL;DR: The low prevalence of Campylobacter and Salmonella in the outdoor environment indicates that it may not be a significant reservoir for transmission of these pathogens on broiler farms. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2013 journal article

Longitudinal Study of Distributions of Similar Antimicrobial-Resistant Salmonella Serovars in Pigs and Their Environment in Two Distinct Swine Production Systems

Applied and Environmental Microbiology, 79(17), 5167–5178.

By: S. Keelara n, H. Scott*, W. Morrow n, W. Gebreyes*, M. Correa n, R. Nayak*, R. Stefanova*, S. Thakur n

MeSH headings : Abattoirs; Animal Husbandry; Animals; Anti-Bacterial Agents / pharmacology; Drug Resistance, Bacterial; Environmental Microbiology; Food Industry; Genotype; Longitudinal Studies; Meat / microbiology; Salmonella Infections, Animal / microbiology; Salmonella enterica / classification; Salmonella enterica / drug effects; Salmonella enterica / isolation & purification; Serotyping; Swine; Swine Diseases / microbiology
TL;DR: A low prevalence of Salmonella is reported in both production systems in pigs on farms, while a higher prevalence was detected among the carcasses at slaughter, clearly indicating an exchange of this pathogen between the pigs and their surroundings. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2013 journal article

Methicillin-Resistant Staphylococcus aureus in Pigs and Farm Workers on Conventional and Antibiotic-Free Swine Farms in the USA

PLOS ONE, 8(5).

By: T. Smith*, W. Gebreyes*, M. Abley*, A. Harper*, B. Forshey*, M. Male*, H. Martin*, B. Molla* ...

MeSH headings : Agriculture; Animals; Anti-Bacterial Agents / pharmacology; Anti-Bacterial Agents / therapeutic use; Bacterial Typing Techniques; Demography; Female; Livestock / microbiology; Male; Methicillin-Resistant Staphylococcus aureus / classification; Methicillin-Resistant Staphylococcus aureus / drug effects; Methicillin-Resistant Staphylococcus aureus / isolation & purification; Staphylococcal Infections / drug therapy; Staphylococcal Infections / microbiology; Staphylococcal Infections / veterinary; Sus scrofa / microbiology; Swine; Swine Diseases / drug therapy; Swine Diseases / microbiology; United States; Weaning
TL;DR: The results confirm the presence of LA-MRSA in pigs and swine farm workers in the USA, but the prevalence found is relatively low compared with European studies. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2013 journal article

Yersinia enterocolitica of Porcine Origin: Carriage of Virulence Genes and Genotypic Diversity

FOODBORNE PATHOGENS AND DISEASE, 10(1), 80–86.

By: D. Tadesse*, P. Bahnson*, J. Funk*, W. Morrow n, M. Abley*, V. Ponte*, S. Thakur n, T. Wittum* ...

MeSH headings : Amplified Fragment Length Polymorphism Analysis; Animals; Bacterial Proteins / genetics; Chromosomes, Bacterial / genetics; Cluster Analysis; DNA, Bacterial / genetics; Disease Reservoirs; Drug Resistance, Bacterial; Feces / microbiology; Foodborne Diseases / microbiology; Genetic Variation; Genotype; Humans; Midwestern United States; North Carolina; Phenotype; Plasmids / genetics; Serotyping; Swine; Swine Diseases / microbiology; Virulence Factors / genetics; Yersinia Infections / microbiology; Yersinia Infections / transmission; Yersinia enterocolitica / genetics; Yersinia enterocolitica / isolation & purification; Yersinia enterocolitica / pathogenicity; Zoonoses; beta-Lactamases / genetics
TL;DR: Yersinia enterocolitica is an important foodborne pathogen, and pigs are recognized as a major reservoir and potential source of pathogenic strains to humans. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2012 journal article

Antimicrobial resistance, toxinotype, and genotypic profiling of clostridium difficile isolates of swine origin

Journal of Clinical Microbiology, 50(7), 2366–2372.

By: P. Fry*, S. Thakur n, M. Abley* & W. Gebreyes*

MeSH headings : Animals; Bacterial Toxins / genetics; Clostridioides difficile / drug effects; Clostridioides difficile / genetics; Clostridioides difficile / isolation & purification; Clostridioides difficile / pathogenicity; Drug Resistance, Bacterial; Electrophoresis, Gel, Pulsed-Field; Feces / microbiology; Genes, Bacterial; Genotype; Humans; Molecular Typing; North Carolina; Ohio; Phylogeography; Polymerase Chain Reaction; Sequence Analysis, DNA; Swine
TL;DR: The study findings indicate that significant proportions of C. difficile in swine are toxigenic and often are associated with antimicrobial resistance genes, although they are not resistant to drugs that are used to treat C.difficile infections. (via Semantic Scholar)
Sources: NC State University Libraries, NC State University Libraries
Added: August 6, 2018

2012 journal article

Longitudinal Study of the Persistence of Antimicrobial-Resistant Campylobacter Strains in Distinct Swine Production Systems on Farms, at Slaughter, and in the Environment

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 78(8), 2698–2705.

By: M. Quintana-Hayashi n & S. Thakur n

MeSH headings : Animal Husbandry; Animal Structures / microbiology; Animals; Anti-Bacterial Agents / pharmacology; Campylobacter coli / drug effects; Campylobacter coli / isolation & purification; Campylobacter jejuni / drug effects; Campylobacter jejuni / isolation & purification; Drug Resistance, Bacterial; Environmental Microbiology; Feces / microbiology; Longitudinal Studies; Microbial Sensitivity Tests; Swine / microbiology
TL;DR: The results highlight the persistence and dissemination of AR Campylobacter from farm to slaughter in ABF and conventionally raised pigs and their environments. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2012 journal article

Longitudinal study comparing the dynamics of Clostridium difficile in conventional and antimicrobial free pigs at farm and slaughter

VETERINARY MICROBIOLOGY, 157(1-2), 172–178.

By: E. Susick n, M. Putnam n, D. Bermudez n & S. Thakur n

author keywords: Clostridium difficile; Antimicrobial resistance; Swine; Toxinotyping; Toxins; Farm; Slaughter
MeSH headings : Animal Husbandry / methods; Animals; Anti-Bacterial Agents / administration & dosage; Clostridioides difficile / classification; Clostridioides difficile / drug effects; Clostridioides difficile / isolation & purification; Drug Resistance, Multiple, Bacterial; Longitudinal Studies; Microbial Sensitivity Tests; Prevalence; Sus scrofa / microbiology; Swine / microbiology; Swine Diseases / microbiology
TL;DR: It is concluded that the unique production practices employed in conventional and ABF production systems have no impact on the pathogen population. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2012 journal article

Molecular Characterization of Salmonella enterica Serotype Enteritidis Isolates from Humans by Antimicrobial Resistance, Virulence Genes, and Pulsed-Field Gel Electrophoresis

FOODBORNE PATHOGENS AND DISEASE, 9(3), 232–238.

By: M. Zou*, S. Keelara n & S. Thakur n

MeSH headings : Ampicillin / pharmacology; Anti-Bacterial Agents / pharmacology; Bacterial Proteins / genetics; Bacterial Proteins / metabolism; DNA Fingerprinting; Disease Outbreaks; Disk Diffusion Antimicrobial Tests; Drug Resistance, Bacterial; Drug Resistance, Multiple, Bacterial; Eggs / microbiology; Electrophoresis, Gel, Pulsed-Field; Humans; Molecular Typing; North Carolina / epidemiology; Phylogeny; Salmonella Food Poisoning / epidemiology; Salmonella Food Poisoning / microbiology; Salmonella enteritidis / drug effects; Salmonella enteritidis / genetics; Salmonella enteritidis / isolation & purification; Salmonella enteritidis / pathogenicity; Seasons; United States / epidemiology; Virulence; Virulence Factors / genetics; Virulence Factors / metabolism
TL;DR: A genotypic similar S. Enteritidis population is identified based on antimicrobial susceptibility, virulence gene, and PFGE fingerprint profiles for the human outbreak due to consumption of contaminated eggs. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2012 journal article

Phylogenetic Analysis Reveals Common Antimicrobial Resistant Campylobacter coli Population in Antimicrobial-Free (ABF) and Commercial Swine Systems

PLOS ONE, 7(9).

By: M. Quintana-Hayashi n & S. Thakur n

MeSH headings : Algorithms; Alleles; Animal Husbandry / methods; Animals; Anti-Infective Agents / pharmacology; Campylobacter coli / metabolism; Cluster Analysis; Genetic Variation; Genotype; Microbial Sensitivity Tests / methods; Multilocus Sequence Typing; Mutation; Phylogeny; Swine; Swine Diseases / microbiology; Swine Diseases / prevention & control
TL;DR: Comparing the population biology of antimicrobial resistant Campylobacter coli isolated from swine reared in the conventional and antimicrobial-free swine production systems reveals a genotypic diverse C. coli population that shares a common ancestry in theventional and ABF swineProduction systems. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2012 journal article

Unilateral Epididymitis Associated with Salmonella Bacteremia in a Dog

Clinical Theriogenology, 4(1), 61–65.

By: C. Perez, M. Whitacre, S. Thakur, S. Keelara, M. Fauls & E. Breitschwerdt

Source: NC State University Libraries
Added: February 18, 2019

2011 chapter

7 - Phenotypic subtyping of foodborne pathogens

In S. Brul, P. M. Fratamico, & T. A. McMeekin (Eds.), Tracing Pathogens in the Food Chain (pp. 141–156). http://www.sciencedirect.com/science/article/pii/B9781845694968500077

By: W. Gebreyes & S. Thakur

Ed(s): S. Brul, P. Fratamico & T. McMeekin

Source: NC State University Libraries
Added: February 27, 2019

2011 journal article

Detection of Clostridium difficile and Salmonella in Feral Swine Population in North Carolina

JOURNAL OF WILDLIFE DISEASES, 47(3), 774–776.

By: S. Thakur n, M. Sandfoss n, S. Kennedy-Stoskopf n & C. DePerno n

MeSH headings : Animals; Animals, Domestic; Animals, Wild; Anti-Bacterial Agents / pharmacology; Clostridioides difficile / drug effects; Clostridioides difficile / isolation & purification; Disease Reservoirs / veterinary; Drug Resistance, Bacterial; Enterocolitis, Pseudomembranous / drug therapy; Enterocolitis, Pseudomembranous / epidemiology; Enterocolitis, Pseudomembranous / transmission; Enterocolitis, Pseudomembranous / veterinary; Female; Male; North Carolina / epidemiology; Prevalence; Salmonella / drug effects; Salmonella / isolation & purification; Salmonella Infections, Animal / drug therapy; Salmonella Infections, Animal / epidemiology; Salmonella Infections, Animal / transmission; Sus scrofa / microbiology; Swine; Swine Diseases / drug therapy; Swine Diseases / epidemiology; Swine Diseases / transmission
TL;DR: Seven and eight feral pigs tested positive for C. difficile and Salmonella, respectively, highlighting the importance of determining the epidemiology of these pathogens in feral pigs. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2011 journal article

Prevalence and Antimicrobial Resistance Profile of Campylobacter Spp. Isolated from Conventional and Antimicrobial-Free Swine Production Systems from Different U.S. Regions

FOODBORNE PATHOGENS AND DISEASE, 8(3), 367–374.

By: D. Tadesse*, P. Bahnson*, J. Funk*, S. Thakur n, W. Morrow n, T. Wittum*, F. DeGraves*, P. Rajala-Schultz*, W. Gebreyes*

MeSH headings : Abattoirs; Animal Husbandry; Animals; Anti-Bacterial Agents / administration & dosage; Anti-Bacterial Agents / pharmacology; Campylobacter / classification; Campylobacter / drug effects; Campylobacter / isolation & purification; Campylobacter Infections / epidemiology; Campylobacter Infections / microbiology; Campylobacter Infections / veterinary; Cohort Studies; Confidence Intervals; Drug Resistance, Bacterial; Feces / microbiology; Great Lakes Region / epidemiology; Microbial Sensitivity Tests / veterinary; Midwestern United States / epidemiology; Polymerase Chain Reaction; Prevalence; Risk Factors; Swine; Swine Diseases / epidemiology; Swine Diseases / microbiology
TL;DR: The finding of ciprofloxacin resistance, particularly from ABF herds, has significant implications on the potential role of risk factors other than mere antimicrobial use for production purposes. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2010 journal article

Antimicrobial Resistance, Virulence, and Genotypic Profile Comparison of Campylobacter jejuni and Campylobacter coli Isolated from Humans and Retail Meats

FOODBORNE PATHOGENS AND DISEASE, 7(7), 835–844.

By: S. Thakur n, S. Zhao*, P. McDermott*, H. Harbottle*, J. Abbott*, L. English*, W. Gebreyes*, D. White*

MeSH headings : Animals; Animals, Domestic / microbiology; Campylobacter Infections / microbiology; Campylobacter Infections / transmission; Campylobacter coli / drug effects; Campylobacter coli / genetics; Campylobacter coli / isolation & purification; Campylobacter coli / pathogenicity; Campylobacter jejuni / drug effects; Campylobacter jejuni / genetics; Campylobacter jejuni / isolation & purification; Campylobacter jejuni / pathogenicity; Ciprofloxacin / pharmacology; Doxycycline / pharmacology; Drug Resistance, Bacterial; Drug Resistance, Multiple, Bacterial; Electrophoresis, Gel, Pulsed-Field; Erythromycin / pharmacology; Genes, Bacterial; Genotype; Humans; Iowa; Meat / microbiology; Polymerase Chain Reaction; Restriction Mapping; Virulence / genetics; Virulence Factors / genetics
TL;DR: Significant differences observed in the distribution of antimicrobial resistance profiles, virulence determinants, and genotypic diversity among C. jejuni and C. coli isolates indicate that there are sources other than retail meats that may also contribute to human Campylobacter infections. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2010 journal article

Phenotypic and Genotypic Heterogeneity of Campylobacter coli Within Individual Pigs at Farm and Slaughter in the US

ZOONOSES AND PUBLIC HEALTH, 57, 100–106.

By: S. Thakur n & W. Gebreyes*

author keywords: Campylobacter; heterogeneity; antimicrobial resistance; swine; minimum inhibitory concentration; multi locus sequence typing
MeSH headings : Abattoirs; Animal Husbandry; Animals; Anti-Bacterial Agents / pharmacology; Bacterial Typing Techniques / veterinary; Campylobacter Infections / drug therapy; Campylobacter Infections / microbiology; Campylobacter Infections / veterinary; Campylobacter coli / drug effects; Campylobacter coli / genetics; Campylobacter coli / isolation & purification; Drug Resistance, Multiple, Bacterial; Feces / microbiology; Genotype; Microbial Sensitivity Tests / veterinary; Multilocus Sequence Typing / veterinary; Phenotype; Swine / genetics; Swine / microbiology; Swine Diseases / drug therapy; Swine Diseases / microbiology
TL;DR: The aim of this study was to determine the phenotypic and genotypic diversity of multiple Campylobacter isolates present within individual (heterogeneity) pig faecal and carcass samples at farm and slaughter, respectively, and to detect multiple C. coli subtypes from individual pig or carcASS samples indicating unprecedented level of heterogeneity. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2010 journal article

Prevalence and Distribution of Salmonella in Organic and Conventional Broiler Poultry Farms

FOODBORNE PATHOGENS AND DISEASE, 7(11), 1363–1371.

By: W. Alali*, S. Thakur n, R. Berghaus*, M. Martin n & W. Gebreyes*

MeSH headings : Animals; Drug Resistance, Bacterial; Drug Resistance, Multiple; Electrophoresis, Gel, Pulsed-Field; Feces / microbiology; Microbial Sensitivity Tests; Organic Agriculture; Phenotype; Poultry / microbiology; Salmonella / classification; Salmonella / genetics; Salmonella / isolation & purification; Streptomycin; Water Microbiology
TL;DR: The results of this cross-sectional study suggest that within this poultry company, the prevalence of fecal Salmonella was lower in certified-organic birds than in conventionally raised birds, andThe prevalence of antimicrobial-resistant Salmoneella was also higher in conventionals raised birds than the two types of farms. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2010 journal article

Prevalence of antimicrobial resistance and association with toxin genes in Clostridium difficile in commercial swine

AMERICAN JOURNAL OF VETERINARY RESEARCH, 71(10), 1189–1194.

By: S. Thakur n, M. Putnam, P. Fry, M. Abley & W. Gebreyes*

MeSH headings : Animals; Anti-Bacterial Agents / pharmacology; Bacterial Toxins / genetics; Clostridioides difficile / drug effects; Clostridioides difficile / genetics; Clostridium Infections / microbiology; Clostridium Infections / veterinary; Female; Male; Microbial Sensitivity Tests; Swine; Swine Diseases / microbiology
TL;DR: The common occurrence of antimicrobial-resistant C difficile and the significant association of toxigenic strains with antimicrobial resistance could contribute to high morbidity in farms with farrowing pigs. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2009 journal article

Genotyping of Campylobacter coli isolated from humans and retail meats using multilocus sequence typing and pulsed-field gel electrophoresis

JOURNAL OF APPLIED MICROBIOLOGY, 106(5), 1722–1733.

By: S. Thakur n, D. White*, P. McDermott*, S. Zhao*, B. Kroft*, W. Gebreyes, J. Abbott*, P. Cullen* ...

author keywords: antimicrobial resistance; Campylobacter coli; humans; multilocus sequence typing; pulsed-field gel electrophoresis; retail meats
MeSH headings : Animals; Anti-Bacterial Agents / pharmacology; Campylobacter Infections / microbiology; Campylobacter coli / classification; Campylobacter coli / drug effects; Campylobacter coli / genetics; Cattle; Chickens; Drug Resistance, Multiple, Bacterial; Electrophoresis, Gel, Pulsed-Field; Food Microbiology; Genetic Variation; Genotype; Humans; Meat / microbiology; Microbial Sensitivity Tests; Phenotype; Phylogeny; Swine; Turkeys
TL;DR: The objective is to determine the antimicrobial resistant profiles and clonality of Campylobacter coli isolated from clinically ill humans and retail meats. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2009 journal article

Longitudinal Study of Salmonella Dispersion and the Role of Environmental Contamination in Commercial Swine Production Systems

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 75(6), 1478–1486.

By: P. Dorr, D. Tadesse*, B. Zewde*, P. Fry*, S. Thakur n & W. Gebreyes*

MeSH headings : Amplified Fragment Length Polymorphism Analysis; Animals; Anti-Bacterial Agents / pharmacology; Bacterial Typing Techniques; Cluster Analysis; Cohort Studies; Cross-Sectional Studies; DNA Fingerprinting; DNA, Bacterial / genetics; Environmental Microbiology; Longitudinal Studies; Microbial Sensitivity Tests; Prevalence; Salmonella / classification; Salmonella / isolation & purification; Salmonella Infections, Animal / microbiology; Serotyping; Swine; Swine Diseases / microbiology
TL;DR: The roles of various environmental sources, such as truck-washing systems, waste-processing lagoons, and other sources, as potential contributors to the exposure and dissemination of Salmonella in commercial swine production systems are investigated. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2009 journal article

Occurrence of spvA Virulence Gene and Clinical Significance for Multidrug-Resistant Salmonella Strains

JOURNAL OF CLINICAL MICROBIOLOGY, 47(3), 777–780.

By: W. Gebreyes*, S. Thakur n, P. Dorr*, D. Tadesse*, K. Post* & L. Wolf*

MeSH headings : Animals; Anti-Bacterial Agents / pharmacology; Bacterial Typing Techniques; Cluster Analysis; DNA Fingerprinting; DNA, Bacterial / genetics; Drug Resistance, Multiple, Bacterial; Electrophoresis, Gel, Pulsed-Field; Genotype; Humans; Microbial Sensitivity Tests; Salmonella / drug effects; Salmonella / genetics; Salmonella / isolation & purification; Salmonella Infections / microbiology; Salmonella Infections, Animal / microbiology; Swine; Swine Diseases / microbiology; Virulence Factors / genetics
TL;DR: It is suggested that MDR strains that also carry specific virulence factors are more likely to be of clinical significance than those that are associated with multidrug-resistant type ACSSuT strains. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2008 article

Molecular epidemiologic investigation of Campylobacter coli in swine production systems, using multilocus sequence typing (vol 72, pg 5666, 2006)

Thakur, S., Morrow, W. E. M., Funk, J. A., Bahnson, P. B., & Gebreyes, W. A. (2008, January). APPLIED AND ENVIRONMENTAL MICROBIOLOGY, Vol. 74, pp. 342–342.

By: S. Thakur n, W. Morrow n, J. Funk n, P. Bahnson n & W. Gebreyes n

TL;DR: Department of Population Health and Pathobiology, College of Veterinary Medicine, North Carolina State University; Department of Animal Science; and Department of Veterinary Preventive Medicine, University of Wisconsin, Madison, Wisconsin are sponsoring this research. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2007 journal article

Occurrence of multidrug resistant Salmonella in antimicrobial-free (ABF) swine production systems

VETERINARY MICROBIOLOGY, 125(3-4), 362–367.

By: S. Thakur*, D. Tadesse*, M. Morrow n & W. Gebreyes*

author keywords: swine; Salmonella species; antimicrobial-free production system; antimicrobials; multidrug resistance
MeSH headings : Animal Husbandry / methods; Animals; Cross-Sectional Studies; Drug Resistance, Multiple, Bacterial; Feces / microbiology; Microbial Sensitivity Tests / veterinary; Prevalence; Salmonella / drug effects; Salmonella / isolation & purification; Swine / microbiology
TL;DR: It is shown that multidrug resistant Salmonella are prevalent in ABF production systems despite the absence of antimicrobial selection pressure, and this study highlights the possible role played by slaughterhouse and other environmental factors in the contamination and dissemination of antimicroicrobial resistantSalmonella in ABf production systems. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2006 journal article

Comparison of prevalence, antimicrobial resistance, and occurrence of multidrug-resistant Salmonella in antimicrobial-free and conventional pig production

JOURNAL OF FOOD PROTECTION, 69(4), 743–748.

By: W. Gebreyes n, S. Thakur n & W. Morrow n

MeSH headings : Animal Husbandry / methods; Animals; Anti-Bacterial Agents / pharmacology; Drug Resistance, Bacterial; Drug Resistance, Multiple, Bacterial; Prevalence; Salmonella Infections, Animal / drug therapy; Salmonella Infections, Animal / epidemiology; Salmonella enterica / classification; Salmonella enterica / drug effects; Salmonella enterica / growth & development; Swine; Swine Diseases / drug therapy; Swine Diseases / epidemiology
TL;DR: While showing the higher likelihood of finding antimicrobial resistance among conventional herds, this study also implies that specific multidrug-resistant strains may occur on antimicrobial-free farms. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2006 journal article

Genetics of Antimicrobial Resistance

Animal Biotechnology, 17(2), 111–124.

By: H. Harbottle*, S. Thakur*, S. Zhao* & D. White*

author keywords: antimicrobial resistance genes; antimicrobial resistance mechanisms; conjugation; integron; plasmid; transposon
MeSH headings : Animals; Anti-Bacterial Agents / pharmacology; Anti-Bacterial Agents / therapeutic use; Bacteria / drug effects; Bacteria / genetics; Bacteria / growth & development; Bacterial Infections / drug therapy; Bacterial Infections / microbiology; Bacterial Infections / veterinary; Drug Resistance, Bacterial / genetics; Drug Resistance, Multiple, Bacterial / genetics; Genome, Bacterial; Humans; Interspersed Repetitive Sequences; Phenotype; Transformation, Genetic
TL;DR: The spread of mobile genetic elements has greatly contributed to the rapid dissemination of antimicrobial resistance among several bacterial genera of human and veterinary importance, leading to a situation where multidrug resistance phenotypes can be transferred to a susceptible recipient via a single genetic event. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: February 18, 2019

2006 journal article

Molecular epidemiologic investigation of Campylobacter coli in swine production systems, using multilocus sequence typing

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 72(8), 5666–5669.

By: S. Thakur n, W. Morrow n, J. Funk*, P. Bahnson* & W. Gebreyes n

MeSH headings : Abattoirs; Animal Husbandry / methods; Animals; Anti-Bacterial Agents / pharmacology; Bacterial Proteins / genetics; Bacterial Typing Techniques; Campylobacter coli / classification; Campylobacter coli / genetics; Campylobacter coli / isolation & purification; Ciprofloxacin / pharmacology; Drug Resistance, Bacterial; Genotype; Molecular Epidemiology; Sequence Analysis, DNA / methods; Swine / microbiology
TL;DR: Multilocus sequence typing of 151 Campylobacter coli isolates from swine reared in conventional and antimicrobial-free production systems revealed high genotypic diversity, particularly among ciprofloxacin-resistant strains. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2006 journal article

Molecular epidemiology and diversity of Salmonella serovar Typhimurium in pigs using phenotypic and genotypic approaches

EPIDEMIOLOGY AND INFECTION, 134(1), 187–198.

By: W. Gebreyes n, C. Altier n & S. Thakur n

MeSH headings : Animal Husbandry; Animals; DNA, Bacterial / analysis; Drug Resistance, Bacterial; Drug Resistance, Multiple; Electrophoresis, Gel, Pulsed-Field; Genotype; Longitudinal Studies; Nucleic Acid Amplification Techniques; Phenotype; Polymerase Chain Reaction; Salmonella Infections, Animal / microbiology; Salmonella typhimurium / classification; Salmonella typhimurium / genetics; Salmonella typhimurium / pathogenicity; Serotyping; Swine; Swine Diseases / microbiology
TL;DR: Three genotyping methods were evaluated; amplified fragment length polymorphism (AFLP), pulsed-field gel electrophoresis (PFGE) and repetitive palindromic extragenic–PCR (Rep-PCR) using 40 isolates and AFLP showed the highest discriminatory index, resolution and throughput. (via Semantic Scholar)
UN Sustainable Development Goal Categories
10. Reduced Inequalities (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2005 journal article

Campylobacter coli in swine production: Antimicrobial resistance mechanisms and molecular epidemiology

JOURNAL OF CLINICAL MICROBIOLOGY, 43(11), 5705–5714.

By: S. Thakur n & W. Gebreyes n

MeSH headings : Abattoirs; Animals; Animals, Domestic; Anti-Bacterial Agents / pharmacology; Campylobacter Infections / epidemiology; Campylobacter Infections / veterinary; Campylobacter Infections / virology; Campylobacter coli / drug effects; Campylobacter coli / genetics; Ciprofloxacin / pharmacology; Costs and Cost Analysis; DNA Gyrase / genetics; Drug Resistance, Multiple, Viral; Electrophoresis, Gel, Pulsed-Field / economics; Electrophoresis, Gel, Pulsed-Field / veterinary; Erythromycin / pharmacology; Evaluation Studies as Topic; Genetic Variation; Microbial Sensitivity Tests; Mutation; Sequence Analysis, DNA / economics; Sequence Analysis, DNA / veterinary; Species Specificity; Swine; Swine Diseases / epidemiology; Swine Diseases / virology; Tetracycline / pharmacology; United States
TL;DR: The findings of this study indicate that multidrug-resistant diverse C. coli strains exhibiting resistance to ciprofloxacin and erythromycin are concerning, since these are the drugs of choice for treating invasive campylobacteriosis cases in humans. (via Semantic Scholar)
UN Sustainable Development Goal Categories
10. Reduced Inequalities (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2005 journal article

Campylobacter coli: prevalence and antimicrobial resistance in antimicrobial-free (ABF) swine production systems

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 56(4), 765–768.

By: W. Gebreyes n, S. Thakur n & W. Morrow n

author keywords: pig; Campylobacter species; antibiotic resistance; antimicrobial-free production
MeSH headings : Abattoirs; Animal Husbandry; Animals; Anti-Bacterial Agents / administration & dosage; Anti-Bacterial Agents / pharmacology; Campylobacter Infections / microbiology; Campylobacter Infections / veterinary; Campylobacter coli / drug effects; Campylobacter coli / isolation & purification; Campylobacter coli / physiology; Carrier State / microbiology; Drug Resistance, Bacterial; Swine / microbiology; Swine Diseases / microbiology
TL;DR: This is the first study reporting the isolation of ciprofloxacin-resistant strains from ABF pigs in the USA and warrants concern. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2005 journal article

Multidrug-resistant Salmonella enterica serovar Muenchen from pigs and humans and potential interserovar transfer of antimicrobial resistance

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 49(2), 503–511.

By: W. Gebreyes n & S. Thakur n

MeSH headings : Animals; Blotting, Southern; Conjugation, Genetic; DNA Fingerprinting; DNA, Bacterial / genetics; Disease Reservoirs; Drug Resistance, Multiple, Bacterial; Electrophoresis, Gel, Pulsed-Field; Gene Transfer, Horizontal; Humans; Integrons / genetics; Microbial Sensitivity Tests; Plasmids / genetics; Salmonella enterica / drug effects; Salmonella enterica / genetics; Salmonella typhimurium / drug effects; Salmonella typhimurium / genetics; Swine
TL;DR: This is the first report to show a high frequency of MDR Salmonella serovar Muenchen strains from pigs and a human strain that is similar to the MDR isolates with the AmpC enzyme previously reported among Salmoneella serovars Newport and Typhimurium strains. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2005 journal article

Prevalence and antimicrobial resistance of Campylobacter in antimicrobial-free and conventional pig production systems

JOURNAL OF FOOD PROTECTION, 68(11), 2402–2410.

By: S. Thakur n & W. Gebreyes n

MeSH headings : Animal Husbandry / methods; Animals; Anti-Bacterial Agents / pharmacology; Campylobacter / drug effects; Campylobacter / isolation & purification; Campylobacter coli / drug effects; Campylobacter coli / isolation & purification; Colony Count, Microbial / veterinary; Drug Resistance, Bacterial; Drug Resistance, Multiple, Bacterial; Food-Processing Industry / standards; Microbial Sensitivity Tests / veterinary; Prevalence; Swine; United States / epidemiology
TL;DR: Findings highlight the high prevalence of antimicrobial-resistant C. coli in both conventional and ABF pig production systems and have significant implications for the persistence of antim antibiotic-resistant Campylobacter in the pig production environment regardless of levels of antimicrobials. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2004 journal article

Characterization of Antimicrobial-Resistant Phenotypes and Genotypes among Salmonella enterica Recovered from Pigs on Farms, from Transport Trucks, and from Pigs after Slaughter

Journal of Food Protection, 67(4), 698–705.

By: W. Gebreyes n, P. Davies n, P. Turkson n, W. Morgan Morrow n, J. Funk n, C. Altier n, S. Thakur n

MeSH headings : Animals; Anti-Bacterial Agents / pharmacology; Colony Count, Microbial; Drug Resistance, Bacterial; Drug Resistance, Multiple, Bacterial; Electrophoresis, Gel, Pulsed-Field; Genotype; Microbial Sensitivity Tests; Phenotype; Salmonella enterica / classification; Salmonella enterica / drug effects; Swine / microbiology
TL;DR: Isolates from the trucks were similar, based on pulsed-field gel electrophoresis patterns, to those from the cecum and mesenteric lymph nodes of pigs on two of the farms, suggesting the probable infection of pigs during transport. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2004 journal article

Trends in antimicrobial resistance, phage types and integrons among Salmonella serotypes from pigs, 1997-2000

Journal of Antimicrobial Chemotherapy, 53(6), 997–1003.

By: W. Gebreyes n, S. Thakur, P. Davies, J. Funk & C. Altier

author keywords: swine; food safety; antibiotic resistance; salmonellae
MeSH headings : Animals; Bacteriophage Typing; Drug Resistance, Bacterial; Feces / microbiology; Integrons / genetics; Microbial Sensitivity Tests; Reverse Transcriptase Polymerase Chain Reaction; Salmonella / drug effects; Salmonella / virology; Salmonella Phages; Swine / microbiology; Swine Diseases / epidemiology; Swine Diseases / microbiology
TL;DR: The findings imply that pigs raised in the commercial production system may pose a risk in serving as reservoirs of resistant Salmonella. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2003 journal article

Molecular Epidemiology of Multi-drug resistant Salmonella enterica serovar Typhimurium isolated from Swine and Humans

Infection, Genetics and Evolution, 2, 277.

By: W. Gebreyes & S. Thakur

Source: NC State University Libraries
Added: February 18, 2019

Employment

Updated: August 7th, 2018 19:33

2007 - present

North Carolina State University Raleigh, NC, US
Professor Population Health and Pathobiology, College of Veterinary Medicine

Education

Updated: October 31st, 2020 09:37

2006 - 2007

Center for Veterinary Medicine, FDA Laurel, Maryland, US
Postdoctoral

2002 - 2005

North Carolina State University Raleigh, NC, US
PhD Population Health and Pathobiology

1998 - 2000

Indian Veterinary Research Institute Izatnagar, Uttar Pradesh, IN
MVSc Veterinary Public Health

1993 - 1998

Govind Ballabh Pant University of Agriculture and Technology Pantnagar, Uttarakhand, IN
BVSc & AH College of Veterinary Medicine

Funding History

Funding history based on the linked ORCID record. Updated: October 31st, 2020 09:39

grant September 1, 2020 - August 31, 2025
Monitoring antimicrobial resistance (AMR) in enteric pathogens isolated from retail meats and seafoods in North Carolina
United States Food and Drug Administration
grant July 5, 2019 - June 30, 2020
Enhancing the WGS based surveillance of Salmonella, Listeria, STEC and other foodborne related bacterial pathogens isolated from food and environment at the national and global level
United States Food and Drug Administration
grant September 5, 2017 - August 31, 2019
Enhancing the whole genome sequence(WGS)based surveillance of Salmonella, Listeria and Shiga Toxin producing Escherichia coli(STEC) isolated from food and environment at the national and global level
United States Food and Drug Administration
grant September 1, 2017 - August 31, 2022
Monitoring antimicrobial resistance (AMR) in Salmonella, Campylobacter, Escherichia coli and Enterococcus spp. isolated from retail meats in North Carolina
United States Food and Drug Administration
grant January 29 - September 30, 2015
Monitoring the Anitmicrobial Resistance Profile of Bacterial Food-borne Pathogens in Humans, Food Animals and Retail Meat in India
United States Department of Agriculture
grant June 30, 2014 - June 30, 2016
Food Safety at the Interface of Food Animals and Fresh Produce: Addressing Pathogen Risks on Sustainable Polycuture Farm
United States Department of Agriculture
grant September 16, 2011 - September 15, 2014
Salmonella serotype distribution in pets presented to veterinary teaching and com
United States Food and Drug Administration
grant September 1, 2008 - August 31, 2012
Molecular Epidemiology of Salmonella in Conventional and Antimicrobial Free Swine Production Systems
National Institute of Food and Agriculture
grant September 1, 2008 - February 28, 2013
An Integrated Approach To Determine Salmonella Dynamics In The Niche-Market Antimicrobial-Free Swine Production System
National Institute of Food and Agriculture

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