Shannon Tracy Holloway

Works (6)

Updated: July 8th, 2023 21:14

2022 article

Effectiveness of Covid-19 Vaccines over a 9-Month Period in North Carolina

Lin, D.-Y., Gu, Y., Wheeler, B., Young, H., Holloway, S., Sunny, S.-K., … Zeng, D. (2022, January 12). New England Journal of Medicine.

By: D. Lin*, Y. Gu *, B. Wheeler *, H. Young*, S. Holloway*, S. Sunny *, Z. Moore*, D. Zeng *

MeSH headings : 2019-nCoV Vaccine mRNA-1273; Ad26COVS1; Adolescent; Adult; Aged; BNT162 Vaccine; COVID-19 / immunology; COVID-19 / mortality; COVID-19 / prevention & control; Child; Female; Hospitalization / statistics & numerical data; Humans; Immunogenicity, Vaccine; Male; Middle Aged; North Carolina / epidemiology; SARS-CoV-2; Vaccine Efficacy / statistics & numerical data; Young Adult
topics (OpenAlex): SARS-CoV-2 and COVID-19 Research; Vaccine Coverage and Hesitancy; COVID-19 Clinical Research Studies
TL;DR: All three Covid-19 vaccines had durable effectiveness in reducing the risks of hospitalization and death, although the two mRNA vaccines provided higher levels of protection than Ad26.COV2.S. (via Semantic Scholar)
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Source: Web Of Science
Added: January 24, 2022

2022 article

Phylogeny-guided microbiome OTU-specific association test (POST)

Huang, C., Callahan, B. J., Wu, M. C., Holloway, S. T., Brochu, H., Lu, W., … Tzeng, J.-Y. (2022, June 7). Microbiome, Vol. 6.

By: C. Huang  n, B. Callahan n , M. Wu *, S. Holloway n, H. Brochu n , W. Lu n , X. Peng n , J. Tzeng n 

author keywords: Association test; Phylogenetic tree; Kernel machine regression
MeSH headings : Computational Biology / methods; Computer Simulation; Female; Humans; Infant, Newborn; Microbiota / genetics; Phylogeny; Premature Birth
topics (OpenAlex): Gut microbiota and health; Reproductive tract infections research; Probiotics and Fermented Foods
TL;DR: This work proposes a local collapsing test called phylogeny-guided microbiome OTU-specific association test (POST), and develops a user friendly R package POSTm, which can enhance the selection performance of associated microbiome features by improving the overall true-positive and false-positive detection. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries, ORCID
Added: June 20, 2022

2021 article

Estimation of the Odds Ratio in a Proportional Odds Model with Censored Time-Lagged Outcome in a Randomized Clinical Trial

Tsiatis, A. A., Davidian, M., & Holloway, S. T. (2021, November 26). Biometrics, Vol. 12.

By: A. Tsiatis n, M. Davidian n  & S. Holloway n

author keywords: augmented inverse probability weighting; censored ordinal categorical outcome; covariate adjustment; COVID-19 treatment; estimating function; marked point process
topics (OpenAlex): Statistical Methods in Clinical Trials; Statistical Methods and Inference; Advanced Causal Inference Techniques
TL;DR: An estimator for the OR in a proportional odds model with censored, time‐lagged categorical outcome that incorporates additional baseline and time‐dependent covariate information and demonstrates that it can result in considerable gains in efficiency relative to simpler approaches is proposed. (via Semantic Scholar)
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Sources: Web Of Science, ORCID, NC State University Libraries
Added: December 17, 2021

2019 book

Dynamic Treatment Regimes

By: A. Tsiatis*, M. Davidian, S. Holloway* & E. Laber n

topics (OpenAlex): Advanced Causal Inference Techniques; Statistical Methods in Clinical Trials; Statistical Methods and Bayesian Inference
Source: Crossref
Added: January 22, 2022

2015 article

A Fast Multiple‐Kernel Method With Applications to Detect Gene‐Environment Interaction

Marceau, R., Lu, W., Holloway, S., Sale, M. M., Worrall, B. B., Williams, S. R., … Tzeng, J. Y. (2015, July 3). Genetic Epidemiology, Vol. 39, pp. 456–468.

By: R. Marceau n, W. Lu n , S. Holloway n, M. Sale *, B. Worrall *, S. Williams *, F. Hsu *, J. Tzeng n 

author keywords: multiple-kernel analysis; kernel machine regression; exon level association test; gene-environment interaction; gene-gene interactions
MeSH headings : Algorithms; Gene-Environment Interaction; Genetic Variation; Homocysteine / metabolism; Humans; Models, Genetic; Quantitative Trait Loci; Regression Analysis; Risk Factors; Software; Stroke / etiology; Vitamins / metabolism
topics (OpenAlex): Folate and B Vitamins Research; Genetic Associations and Epidemiology; MicroRNA in disease regulation
TL;DR: This work proposes a computationally efficient and statistically rigorous “fastKM” algorithm for multikernel analysis that is based on a low‐rank approximation to the nuisance effect kernel matrices and shows that it has similar performance to an EM‐based KM approach for quantitative traits while running much faster. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2014 article

Discussion of “Combining biomarkers to optimize patient treatment recommendation”

Laber, E. B., Tsiatis, A. A., Davidian, M., & Holloway, S. T. (2014, June 2). Discussion of “Combining biomarkers to optimize patient treatment recommendation.” Biometrics, Vol. 70, pp. 707–710.

By: E. Laber n, A. Tsiatis n, M. Davidian n  & S. Holloway n

MeSH headings : Biomarkers, Tumor / blood; Biometry / methods; Breast Neoplasms / blood; Breast Neoplasms / therapy; Data Interpretation, Statistical; Female; Humans; Male; Outcome Assessment, Health Care / methods
topics (OpenAlex): Statistical Methods in Clinical Trials; Statistical Methods and Inference; Advanced Causal Inference Techniques
TL;DR: It is shown how the method of KJH can be used with existing policy-search methods to construct a treatment rule that is interpretable, logistically feasible, parsimonious, or otherwise appealing. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

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