@article{trivedi_clark_long_daniel_anderson_zheng_2023, title={Assessing the Mental Wellbeing and Help-Seeking Behaviors of Pre-Veterinary Undergraduates at a Land-Grant Institution}, ISSN={["1943-7218"]}, DOI={10.3138/jvme-2022-0096}, abstractNote={ Recent research conducted within the veterinary profession has reported higher rates of depression and stress than the general US population. While this decline in mental well-being has been documented in Doctor of Veterinary Medicine (DVM) students and veterinary professionals, there is a lack of research on the mental well-being of the pre-veterinary population. This gap led us to conduct a survey in the fall of 2021 utilizing the DASS-21 and ATSPPH-sf inventories to assess the levels of depression, anxiety, stress, and help-seeking stigma in pre-veterinary students to better understand when the decline in veterinary mental well-being begins. A pre-test survey was completed by 233 pre-veterinary students in September, and an identical post-test survey was completed by 184 pre-veterinary students in November. From the pre- and post-test data, depression, anxiety, and stress scores increased as students advanced in academic status during their undergraduate degree. Juniors reported the highest averages of depression, anxiety, and stress compared with their peers. In the post-test, sophomores and juniors exhibited higher rates of depression than freshmen, and juniors and seniors exhibited higher rates of stress than freshmen. Current VMCAS applicants exhibited higher levels of stress than non-VMCAS applicants in the pre-test and lower levels of stress in the post-test. In both the pre-test and post-test data, respondents averaged a neutral attitude toward help-seeking. Based on these results, a decline in pre-veterinary mental well-being occurs as students’ progress in their undergraduate career and should be further studied to assess its impact on Doctor of Veterinary Medicine and veterinary professional well-being. }, journal={JOURNAL OF VETERINARY MEDICAL EDUCATION}, author={Trivedi, Shweta and Clark, Jessica C. and Long, Linzi and Daniel, Georgia A. and Anderson, Samantha M. and Zheng, Yaxin}, year={2023}, month={Mar} } @misc{burnham_ange-van heugten_mckenney_minter_trivedi_2023, title={Conservation Innovations and Future Directions for the Study of Rhinoceros Gut Microbiome}, volume={4}, ISSN={["2673-5636"]}, url={https://www.mdpi.com/2673-5636/4/2/30}, DOI={10.3390/jzbg4020030}, abstractNote={Rhinoceros are among the largest and most endangered herbivores in the world. Three of the five extant species are critically endangered, with poaching and habitat loss contributing heavily to declines. The gut microbiome is an essential facet of host health and digestion, mediating a variety of immune and physiological functions. Certain microbes have the potential to serve as biomarkers for reproductive outcomes and predictors of disease susceptibility. Therefore, assessing gut microbial dynamics in relation to wild and managed rhinoceros populations has particular relevance for zoos and other conservation organizations that maintain assurance populations of these charismatic megafauna. The functional gut microbiomes associated with all rhinoceros species remain poorly studied, and many published reports are limited by small sample sizes and sex biases. In this review, we synthesize current research to examine the rhinoceros gut microbiome under human management and resulting conservation implications, address common pitfalls of wildlife gut microbiome studies, and propose future avenues of research in this field.}, number={2}, journal={JOURNAL OF ZOOLOGICAL AND BOTANICAL GARDENS}, author={Burnham, Christina M. and Ange-van Heugten, Kimberly and McKenney, Erin A. and Minter, Larry J. and Trivedi, Shweta}, year={2023}, month={Jun}, pages={396–412} } @article{burnham_mckenney_ange-van heugten_minter_trivedi_2023, title={Effect of fecal preservation method on captive southern white rhinoceros gut microbiome}, volume={3}, ISSN={["2328-5540"]}, DOI={10.1002/wsb.1436}, abstractNote={Abstract}, journal={WILDLIFE SOCIETY BULLETIN}, author={Burnham, Christina M. and McKenney, Erin A. and Ange-van Heugten, Kimberly and Minter, Larry J. and Trivedi, Shweta}, year={2023}, month={Mar} } @article{burnham_mckenney_ange-van heugten_minter_trivedi_2023, title={Effects of age, seasonality, and reproductive status on the gut microbiome of Southern White Rhinoceros (Ceratotherium simum simum) at the North Carolina zoo}, volume={5}, ISSN={["2524-4671"]}, DOI={10.1186/s42523-023-00249-5}, abstractNote={Abstract}, number={1}, journal={ANIMAL MICROBIOME}, author={Burnham, Christina M. M. and McKenney, Erin A. A. and Ange-van Heugten, Kimberly and Minter, Larry J. J. and Trivedi, Shweta}, year={2023}, month={May} } @article{trivedi_deuser_zheng_2023, title={Impact of Applying Quality Matters Essential Standards in an Animal Science Physiology Course.}, volume={101}, ISSN={["1525-3163"]}, DOI={10.1093/jas/skad068.134}, abstractNote={Abstract}, journal={JOURNAL OF ANIMAL SCIENCE}, author={Trivedi, Shweta and Deuser, Kylie and Zheng, Yaxin}, year={2023}, month={May} } @article{deuser_sanchez_mendoza-moran_winzeler_zheng_trivedi_2023, title={Student perceptions of the impact of quality matters essential standards in an animal physiology course}, volume={7}, ISSN={["2573-2102"]}, DOI={10.1093/tas/txad112}, abstractNote={Abstract}, number={1}, journal={TRANSLATIONAL ANIMAL SCIENCE}, author={Deuser, Kylie and Sanchez, Rebecca P. and Mendoza-Moran, Arlene and Winzeler, Bethanne and Zheng, Yaxin and Trivedi, Shweta}, year={2023}, month={Jan} } @article{trivedi_clark_deprospero_royal_see_2021, title={A novel career development course for animal science students pursuing veterinary college admissions}, volume={5}, ISSN={["2573-2102"]}, DOI={10.1093/tas/txab106}, abstractNote={Abstract}, number={3}, journal={TRANSLATIONAL ANIMAL SCIENCE}, author={Trivedi, Shweta and Clark, Jessica C. and Deprospero, Dylan and Royal, Kenneth and See, Miles Todd}, year={2021}, month={Jul} } @article{trivedi_burnham_capobianco_boshoff_zheng_pettiglio_ange-van heugten_bissell_minter_2021, title={Analysis of Blood Biochemistry of Free Ranging and Human-Managed Southern White Rhinoceros (Ceratotherium simum simum) Using the i-STAT Alinity v®}, volume={2021}, ISSN={2042-0048 2090-8113}, url={http://dx.doi.org/10.1155/2021/2665956}, DOI={10.1155/2021/2665956}, abstractNote={Handheld point-of-care blood analyzers deliver rapid results for biochemical and hematologic parameters, making them very useful in veterinary clinics and in fieldwork applications. This study compared the biochemical and hematologic parameters generated by the novel point-of-care analyzer i-STAT® Alinity V CHEM8+ cartridge between human-managed and free ranging populations of southern white rhinoceros (Ceratotherium simum simum). In addition, a novel reference interval for ionized calcium (iCa), a parameter of diagnostic and prognostic importance, was established for southern white rhinoceros. Blood samples were obtained from 10 managed (6 at NC Zoo and 4 at Busch Gardens Tampa Bay in 2019) and 30 free ranging white rhinoceros (collected in South Africa between 2018 and 2019) and analyzed using the i-STAT. Multiple parameters were higher ( P < 0.05 ) in free ranging versus managed animals including potassium, blood urea nitrogen, creatinine, glucose, hematocrit, and hemoglobin. Conversely, iCa concentrations were higher ( P < 0.05 ) in the managed populations of white rhinoceros. The RI determined for iCa was 1.36–1.56 mmol/L, with a mean of 1.46 mmol/L, and was determined using the guidelines from the American Society for Veterinary Clinical Pathology. There was no difference in anion gap, chlorine, total carbon dioxide, or sodium between the populations. Seasonality and locality of sampling as well as diet may be contributing factors to the higher iCa concentrations in managed rhinoceros. The six elevated parameters in free ranging rhinoceros are likely attributable to dehydration compounded by capture stress. This data provides insight into the state of several biochemical and hematologic parameters in southern white rhinoceros and will allow veterinarians to better assess the health of both managed and free ranging populations.}, journal={Veterinary Medicine International}, publisher={Hindawi Limited}, author={Trivedi, Shweta and Burnham, Christina M. and Capobianco, Christian M. and Boshoff, Christiaan and Zheng, Yaxin and Pettiglio, Jordan Wood and Ange-van Heugten, Kimberly and Bissell, Heidi D. and Minter, Larry J.}, editor={Hussni, Carlos AlbertoEditor}, year={2021}, month={Jul}, pages={1–6} } @article{trivedi_clark_royal_2021, title={The Impact of COVID-19 on Pre-Veterinary Opportunities and Recommendations for DVM Admissions}, volume={5}, ISSN={["1943-7218"]}, DOI={10.3138/jvme-2020-0145}, abstractNote={ During the summer of 2020, a survey-based study was conducted at North Carolina State University, a land-grant university, to evaluate the impact of COVID-19 on pre-veterinary students’ ability to gain experience hours for Doctor of Veterinary Medicine (DVM) admissions. Of the 286 respondents (47% of the respondent pool), 92% reported losing at least one animal, veterinary, research, extracurricular, or work opportunity due to COVID-19, and 59% were not able to find a replacement. Of the lost experiences, 74 (20.8%) were for academic credit, resulting in 131 total academic credit hours lost, while only 12 credit hours were gained via alternative experiences. Of respondents, 30% (29.7%) identified as applicants of the 2020–2021 Veterinary Medical College Application Service (VMCAS) cycle. More than half (52.6%) of the sample identified being concerned about the strength of their VMCAS experiences due to these lost opportunities. Many respondents reported considering delaying application submissions by taking a gap year (17.5%) or having had their intended graduation timeline affected (14.8%). Since the majority of veterinary colleges utilize a holistic review process, this study provides a basis for understanding the effects of COVID-19 on the duration, depth, and diversity of experiences gained by future DVM applicants. This article also provides recommendations for DVM admissions adaptations based on the outcomes of the data. }, journal={JOURNAL OF VETERINARY MEDICAL EDUCATION}, author={Trivedi, Shweta and Clark, Jessica C. and Royal, Kenneth D.}, year={2021}, month={May} } @article{trivedi_clark_see_2021, title={Veterinary Professions Advising Center: an innovative approach to preveterinary advising for Animal Science students}, volume={5}, ISSN={["2573-2102"]}, DOI={10.1093/tas/txab064}, abstractNote={Abstract}, number={2}, journal={TRANSLATIONAL ANIMAL SCIENCE}, author={Trivedi, Shweta and Clark, Jessica C. and See, M. Todd}, year={2021}, month={Apr} } @article{verhein_mccaw_gladwell_trivedi_bushel_kleeberger_2015, title={Novel Roles for Notch3 and Notch4 Receptors in Gene Expression and Susceptibility to Ozone-Induced Lung Inflammation in Mice}, volume={123}, ISSN={["1552-9924"]}, DOI={10.1289/ehp.1408852}, abstractNote={Background Ozone is a highly toxic air pollutant and global health concern. Mechanisms of genetic susceptibility to ozone-induced lung inflammation are not completely understood. We hypothesized that Notch3 and Notch4 are important determinants of susceptibility to ozone-induced lung inflammation. Methods Wild-type (WT), Notch3 (Notch3–/–), and Notch4 (Notch4–/–) knockout mice were exposed to ozone (0.3 ppm) or filtered air for 6–72 hr. Results Relative to air-exposed controls, ozone increased bronchoalveolar lavage fluid (BALF) protein, a marker of lung permeability, in all genotypes, but significantly greater concentrations were found in Notch4–/– compared with WT and Notch3–/– mice. Significantly greater mean numbers of BALF neutrophils were found in Notch3–/– and Notch4–/– mice compared with WT mice after ozone exposure. Expression of whole lung Tnf was significantly increased after ozone in Notch3–/– and Notch4–/– mice, and was significantly greater in Notch3–/– compared with WT mice. Statistical analyses of the transcriptome identified differentially expressed gene networks between WT and knockout mice basally and after ozone, and included Trim30, a member of the inflammasome pathway, and Traf6, an inflammatory signaling member. Conclusions These novel findings are consistent with Notch3 and Notch4 as susceptibility genes for ozone-induced lung injury, and suggest that Notch receptors protect against innate immune inflammation. Citation Verhein KC, McCaw Z, Gladwell W, Trivedi S, Bushel PR, Kleeberger SR. 2015. Novel roles for Notch3 and Notch4 receptors in gene expression and susceptibility to ozone-induced lung inflammation in mice. Environ Health Perspect 123:799–805; http://dx.doi.org/10.1289/ehp.1408852}, number={8}, journal={ENVIRONMENTAL HEALTH PERSPECTIVES}, author={Verhein, Kirsten C. and McCaw, Zachary and Gladwell, Wesley and Trivedi, Shweta and Bushel, Pierre R. and Kleeberger, Steven R.}, year={2015}, month={Aug}, pages={799–805} } @article{trivedi_arasu_2005, title={Evaluation of endogenous reference genes for real-time PCR quantification of gene expression in Ancylostoma caninum}, volume={143}, ISSN={["1872-9428"]}, DOI={10.1016/j.molbiopara.2005.05.011}, number={2}, journal={MOLECULAR AND BIOCHEMICAL PARASITOLOGY}, author={Trivedi, S and Arasu, P}, year={2005}, month={Oct}, pages={241–244} }