Works (5)

Updated: July 5th, 2023 15:55

2015 journal article

Transgenic and Mutation-Based Suppression of a Berberine Bridge Enzyme-Like (BBL) Gene Family Reduces Alkaloid Content in Field-Grown Tobacco

PLOS ONE, 10(2).

By: R. Lewis n, H. Lopez n, S. Bowen n, K. Andres n, W. Steede n & R. Dewey n

co-author countries: United States of America 🇺🇸
MeSH headings : Alkaloids / biosynthesis; Alkaloids / chemistry; Gene Expression Regulation, Plant; Mutation; Plant Proteins / antagonists & inhibitors; Plant Proteins / genetics; Plant Proteins / metabolism; Plants, Genetically Modified / genetics; Plants, Genetically Modified / metabolism; RNA Interference; Tobacco / genetics; Tobacco / growth & development; Tobacco / metabolism
Source: Web Of Science
Added: August 6, 2018

2012 journal article

Development of CAPS and dCAPS markers for CYP82E4, CYP82E5v2 and CYP82E10 gene mutants reducing nicotine to nornicotine conversion in tobacco

MOLECULAR BREEDING, 29(3), 589–599.

By: D. Li*, R. Lewis n, A. Jack*, R. Dewey n, S. Bowen n & R. Miller*

co-author countries: United States of America 🇺🇸
author keywords: CAPS markers; dCAPS markers; Nicotiana tabacum; Nicotine conversion; Tobacco harm reduction; Mutation breeding
Source: Web Of Science
Added: August 6, 2018

2010 journal article

Three nicotine demethylase genes mediate nornicotine biosynthesis in Nicotiana tabacum L Functional characterization of the CYP82E10 gene

PHYTOCHEMISTRY, 71(17-18), 1988–1998.

By: R. Lewis n, S. Bowen n, M. Keogh n & R. Dewey n

co-author countries: United States of America 🇺🇸
author keywords: Nicotiana tabacum; Solanaceae; Gene function; Alkaloids; Nornicotine; Tobacco specific nitrosamine (TSNA); Cytochrome P450; CYP82E10
MeSH headings : Carcinogens / chemistry; Carcinogens / pharmacology; Cytochrome P-450 Enzyme System / genetics; Cytochrome P-450 Enzyme System / metabolism; Molecular Structure; Nicotine / analogs & derivatives; Nicotine / biosynthesis; Nicotine / chemistry; Nicotine / genetics; Nicotine / metabolism; Nitrosamines / chemistry; Nitrosamines / pharmacology; Plant Leaves / chemistry; Plant Leaves / genetics; Plant Leaves / metabolism; Plant Proteins / genetics; Plant Proteins / metabolism; Tobacco / chemistry; Tobacco / enzymology; Tobacco / genetics
Source: Web Of Science
Added: August 6, 2018

2008 journal article

CYP82E4-mediated nicotine to nornicotine conversion in tobacco is regulated by a senescence-specific signaling pathway

PLANT MOLECULAR BIOLOGY, 66(4), 415–427.

By: M. Chakrabarti*, S. Bowen n, N. Coleman*, K. Meekins*, R. Dewey n & B. Siminszky*

co-author countries: United States of America 🇺🇸
author keywords: alkaloid; cytochrome P450; SAG; senescence-associated gene; stress; transcriptional regulation
MeSH headings : Aging / genetics; Cytochrome P-450 Enzyme System / genetics; Cytochrome P-450 Enzyme System / metabolism; Ethylenes / pharmacology; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Plant; Glucuronidase / genetics; Glucuronidase / metabolism; Plant Leaves / enzymology; Plant Leaves / growth & development; Plant Proteins / genetics; Plant Proteins / metabolism; Plants, Genetically Modified / enzymology; Promoter Regions, Genetic; Signal Transduction; Tobacco / drug effects; Tobacco / enzymology; Tobacco / genetics; Tobacco / growth & development
Source: Web Of Science
Added: August 6, 2018

2007 journal article

Functional analysis of nicotine demethylase genes reveals insights into the evolution of modern tobacco

JOURNAL OF BIOLOGICAL CHEMISTRY, 282(1), 249–256.

By: L. Gavilano*, N. Coleman*, S. Bowen n & B. Siminszky*

co-author countries: United States of America 🇺🇸
MeSH headings : Alleles; Amino Acid Sequence; Cytochrome P-450 Enzyme System / biosynthesis; Cytochrome P-450 Enzyme System / chemistry; Kinetics; Models, Biological; Models, Genetic; Molecular Sequence Data; Nicotine; Oxidoreductases / genetics; Oxidoreductases / metabolism; Phenotype; Plant Proteins / biosynthesis; Plant Proteins / chemistry; Protein Structure, Tertiary; Reverse Transcriptase Polymerase Chain Reaction; Sequence Homology, Amino Acid; Stem Cells / metabolism; Tobacco / enzymology; Tobacco / genetics; Transcription, Genetic
Source: Web Of Science
Added: August 6, 2018

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