Works (93)

Updated: March 2nd, 2024 03:47

2024 article

Developmental exposure to pesticides that disrupt retinoic acid signaling causes persistent retinoid and behavioral dysfunction in zebrafish

Hawkey, A. B., Shekey, N., Dean, C., Asrat, H., Koburov, R., Holloway, Z. R., … Levin, E. D. (2024, January 17). TOXICOLOGICAL SCIENCES, Vol. 1.

By: A. Hawkey*, N. Shekey n, C. Dean*, H. Asrat*, R. Koburov*, Z. Holloway*, S. Kullman n, E. Levin*

co-author countries: United States of America 🇺🇸
author keywords: zebrafish; development; neurobehavioral toxicology; retinoic acid receptors
Sources: Web Of Science, ORCID
Added: January 29, 2024

2023 article

Comparative analysis of sucrose-embedding for whole-body zebrafish MSI by IR-MALDESI

Wang, M. F., Ritter, M. M., Kullman, S. W., & Muddiman, D. C. (2023, August 29). ANALYTICAL AND BIOANALYTICAL CHEMISTRY, Vol. 8.

By: M. Wang n, M. Ritter n, S. Kullman n & D. Muddiman n

co-author countries: United States of America 🇺🇸
author keywords: IR-MALDESI; Mass spectrometry imaging; Sucrose; PFA; Zebrafish
Sources: Web Of Science, ORCID
Added: September 25, 2023

2023 journal article

Legacy and emerging per- and polyfluoroalkyl substances suppress the neutrophil respiratory burst

JOURNAL OF IMMUNOTOXICOLOGY, 20(1).

By: D. Phelps*, A. Palekar, H. Conley*, G. Ferrero, J. Driggers*, K. Linder*, S. Kullman n, D. Reif n ...

co-author countries: United States of America 🇺🇸
author keywords: Innate immunity; neutrophils; per- and polyfluoroalkyl substances (PFAS); reactive oxygen species; zebrafish
MeSH headings : Animals; Humans; Zebrafish; Neutrophils; Reactive Oxygen Species; Respiratory Burst; Fluorocarbons / toxicity; Alkanesulfonic Acids / toxicity; Environmental Pollutants
Sources: ORCID, Web Of Science
Added: February 15, 2023

2023 article

Maximized Spatial Information and Minimized Acquisition Time of Top-Hat IR-MALDESI-MSI of Zebrafish Using Nested Regions of Interest (nROIs)

Joignant, A. N., Ritter, M. M., Knizner, K. T., Garrard, K. P., Kullman, S. W., & Muddiman, D. C. (2023, August 1). JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, Vol. 8.

By: A. Joignant n, M. Ritter n, K. Knizner n, K. Garrard n, S. Kullman n & D. Muddiman n

co-author countries: United States of America 🇺🇸
author keywords: IR-MALDESI; mass spectrometry imaging; spatialresolution; nested region of interest; zebrafish
Sources: Web Of Science, ORCID
Added: August 21, 2023

2022 journal article

Confirmation of high-throughput screening data and novel mechanistic insights into FXR-xenobiotic interactions by orthogonal assays

CURRENT RESEARCH IN TOXICOLOGY, 3.

By: J. Hamm*, D. Mahapatra n, M. Knuth n, J. Abedini*, M. Lingerfelt*, S. Ekins*, S. Kullman n

co-author countries: United States of America 🇺🇸
author keywords: ToxCast; Farnesoid X receptor; High -throughput screening; Teleost models; Medaka
Sources: Web Of Science, ORCID
Added: January 23, 2023

2022 journal article

Nonylphenol Polyethoxylates Enhance Adipose Deposition in Developmentally Exposed Zebrafish

Toxics, 10(2), 99.

co-author countries: United States of America 🇺🇸
author keywords: endocrine disrupting chemicals; adipogenesis; alkylphenol ethoxylates; ethoxylated surfactants; mixtures; obesogen
Sources: Web Of Science, ORCID
Added: March 14, 2022

2022 article

Nonylphenol Polyethoxylates Enhance Adipose Deposition in Developmentally Exposed Zebrafish (vol 10, 99, 2022)

Kassotis, C. D., LeFauve, M. K., Chiang, Y.-T. T., Knuth, M. M., Schkoda, S., & Kullman, S. W. (2022, July). TOXICS, Vol. 10.

co-author countries: United States of America 🇺🇸
Sources: Web Of Science, ORCID
Added: August 8, 2022

2022 article

TCDD alters essential transcriptional regulators of osteogenic differentiation in multipotent mesenchymal stem cells

Watson, A. L. T. D., Carmona Baez, A., Jima, D., Reif, D., Ding, J., Roberts, R., & Kullman, S. W. (2022, November 12). TOXICOLOGICAL SCIENCES, Vol. 11.

By: A. Watson n, A. Carmona Baez n, D. Jima n, D. Reif n, J. Ding*, R. Roberts n, S. Kullman n

co-author countries: Canada 🇨🇦 United States of America 🇺🇸
author keywords: mesenchymal stem cell; AhR; cell differentiation
MeSH headings : Humans; Osteogenesis / genetics; Polychlorinated Dibenzodioxins / toxicity; Cell Differentiation; Fibroblast Growth Factors / metabolism; Mesenchymal Stem Cells / metabolism; Cells, Cultured; Osteoblasts
Sources: ORCID, Web Of Science
Added: November 12, 2022

2021 journal article

Vitamin D deficiency promotes accumulation of bioactive lipids and increased endocannabinoid tone in zebrafish

JOURNAL OF LIPID RESEARCH, 62.

By: M. Knuth n, W. Stutts n, M. Ritter n, K. Garrard n & S. Kullman n

co-author countries: United States of America 🇺🇸
author keywords: MS; metabolomics; lipidomics; lipids; nutrition; endocannabinoid biosynthesis; MSI; IR-MALDESI; anandamide
MeSH headings : Animals; Endocannabinoids / metabolism; Lipid Metabolism; Lipids / chemistry; Vitamin D Deficiency / metabolism; Zebrafish
Sources: Web Of Science, ORCID
Added: October 19, 2021

2020 article

20th Pollutant Responses in Marine Organisms (PRIMO 20): Global issues and fundamental mechanisms caused by pollutant stress in marine and freshwater organisms

Baldwin, W. S., Bain, L. J., Di Giulio, R., Kullman, S., Rice, C. D., Ringwood, A. H., & Hurk, P. (2020, October). AQUATIC TOXICOLOGY, Vol. 227.

By: W. Baldwin*, L. Bain*, R. Di Giulio*, S. Kullman n, C. Rice*, A. Ringwood*, P. Hurk*

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Aquatic Organisms / drug effects; Aquatic Organisms / physiology; Ecosystem; Endocrine Disruptors; Environmental Monitoring; Environmental Pollutants / pharmacology; Fishes; Fresh Water; Humans; Plastics; Water Pollutants, Chemical / toxicity
Sources: Web Of Science, ORCID
Added: October 19, 2020

2020 journal article

Developmental exposure of zebrafish to vitamin D receptor acting drugs and environmental toxicants disrupts behavioral function

NEUROTOXICOLOGY AND TERATOLOGY, 81.

By: A. Oliveri*, L. Glazer*, D. Mahapatra n, S. Kullman n & E. Levin*

co-author countries: United States of America 🇺🇸
author keywords: Vitamin D receptor; Agonists; Antagonists; Zebrafish, larvae; Neurodevelopment; Behavioral toxicology
MeSH headings : Animals; Behavior, Animal / drug effects; Habituation, Psychophysiologic / drug effects; Hazardous Substances / pharmacology; Motor Activity / drug effects; Neurotoxicity Syndromes / etiology; Pharmaceutical Preparations; Receptors, Calcitriol / metabolism; Reflex, Startle / drug effects; Zebrafish / physiology
Sources: Web Of Science, ORCID
Added: October 12, 2020

2020 journal article

Methods for Cryosectioning and Mass Spectrometry Imaging of Whole-Body Zebrafish

Journal of the American Society for Mass Spectrometry, 31(4), 768–772.

By: W. Stutts n, M. Knuth n, M. Ekelöf n, D. Mahapatra n, S. Kullman n & D. Muddiman n

co-author countries: United States of America 🇺🇸
author keywords: zebrafish; mass spectrometry imaging; cryosectioning; IR-MALDESI; lipids
MeSH headings : Animals; Cryoultramicrotomy / methods; Lipids / analysis; Male; Molecular Imaging; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / methods; Zebrafish / metabolism
Sources: Crossref, ORCID
Added: February 6, 2021

2020 journal article

Thyroid Receptor Antagonism of Chemicals Extracted from Personal Silicone Wristbands within a Papillary Thyroid Cancer Pilot Study

ENVIRONMENTAL SCIENCE & TECHNOLOGY, 54(23), 15296–15312.

co-author countries: United States of America 🇺🇸
MeSH headings : Adult; Antithyroid Agents; Case-Control Studies; Environmental Monitoring; Flame Retardants / analysis; HEK293 Cells; Halogenated Diphenyl Ethers / analysis; Humans; North Carolina; Pilot Projects; Prospective Studies; Silicones; Thyroid Cancer, Papillary; Thyroid Neoplasms
Sources: Web Of Science, ORCID
Added: January 19, 2021

2020 journal article

Vitamin D deficiency serves as a precursor to stunted growth and central adiposity in zebrafish

SCIENTIFIC REPORTS, 10(1).

By: M. Knuth n, D. Mahapatra n, D. Jima n, D. Wan*, B. Hammock*, M. Law n, S. Kullman n

co-author countries: United States of America 🇺🇸
MeSH headings : Adipose Tissue / metabolism; Adiposity / physiology; Animals; Diet; Growth Disorders / metabolism; Hyperplasia / etiology; Hyperplasia / physiopathology; Liver / metabolism; Obesity / metabolism; Obesity, Abdominal / complications; Vitamin D / metabolism; Vitamin D Deficiency / metabolism; Vitamin D Deficiency / physiopathology; Zebrafish / growth & development; Zebrafish / metabolism; Zebrafish Proteins / metabolism
Sources: Web Of Science, ORCID
Added: October 26, 2020

2020 journal article

Zebrafish show long-term behavioral impairments resulting from developmental vitamin D deficiency

PHYSIOLOGY & BEHAVIOR, 224.

By: A. Oliveri*, M. Knuth n, L. Glazer*, J. Bailey*, S. Kullman n & E. Levin*

co-author countries: United States of America 🇺🇸
author keywords: Vitamin D deficiency; Zebrafish; Anxiety; Neurodevelopment; Behavioral toxicology
MeSH headings : Animals; Behavior, Animal; Reflex, Startle; Swimming; Vitamin D Deficiency / complications; Zebrafish
Sources: Web Of Science, ORCID
Added: August 24, 2020

2019 chapter

Alterations in skeletogenesis during medaka embryonic development

In K. Murata, M. Kinoshita, K. Naruse, M. Tanaka, & Y. Kamei (Eds.), Medaka: Biology, Management, and Experimental Protocols (2nd ed.). Hoboken, NJ: Wiley.

By: S. Kullman & A. Watson

Ed(s): K. Murata, M. Kinoshita, K. Naruse, M. Tanaka & Y. Kamei

Source: NC State University Libraries
Added: September 15, 2022

2019 journal article

Evidence for Aryl hydrocarbon Receptor-Mediated Inhibition of Osteoblast Differentiation in Human Mesenchymal Stem Cells

TOXICOLOGICAL SCIENCES, 167(1), 145–156.

By: A. Watson n, R. Nordberg n, E. Loboa n & S. Kullman n

co-author countries: United States of America 🇺🇸
author keywords: aryl hydrocarbon receptor; 2,3,7,8-tetrachlorodibenzo-p-dioxin; TCDD; mesenchymal stem cell; osteoblast differentiation; skeletal toxicity; bone toxicity
MeSH headings : Basic Helix-Loop-Helix Transcription Factors / agonists; Cell Differentiation / drug effects; Fibroblast Growth Factor 9 / genetics; Fibroblast Growth Factors / genetics; Humans; Ligands; Mesenchymal Stem Cells / cytology; Mesenchymal Stem Cells / drug effects; Mesenchymal Stem Cells / metabolism; Osteoblasts / cytology; Osteoblasts / drug effects; Osteoblasts / metabolism; Osteogenesis / drug effects; Osteogenesis / genetics; Polychlorinated Dibenzodioxins / toxicity; Receptors, Aryl Hydrocarbon / agonists; Up-Regulation
Sources: Web Of Science, ORCID
Added: April 15, 2019

2019 review

Maternal vitamin D deficiency and developmental origins of health and disease (DOHaD)

[Review of ]. JOURNAL OF ENDOCRINOLOGY, 241(2), R65–R80.

By: F. Ideraabdullah*, A. Belenchia*, C. Rosenfeld*, S. Kullman n, M. Knuth n, D. Mahapatra n, M. Bereman n, E. Levinlo, C. Peterson*

co-author countries: United States of America 🇺🇸
author keywords: vitamin D deficiency; DOHAD; metabolic disorders; autism; neurobehavioral disorders; animal models
Sources: Web Of Science, ORCID
Added: June 17, 2019

2018 journal article

An object-oriented Bayesian network approach for establishing swine manure-borne natural estrogenic compounds budget

SCIENCE OF THE TOTAL ENVIRONMENT, 639, 815–825.

By: B. Lee*, S. Kullman n, E. Yost n, L. Worley-Davis n & K. Reckhow*

co-author countries: United States of America 🇺🇸
author keywords: Natural estrogens; Swine CAFO; Total facility estrogen budget; OOBN
MeSH headings : Animals; Bayes Theorem; Estradiol; Estrogens / analysis; Estrogens / metabolism; Estrone; Female; Lactation; Manure / analysis; North Carolina; Swine; Waste Disposal, Fluid / methods; Water Pollutants, Chemical / analysis; Water Pollutants, Chemical / metabolism
Sources: Web Of Science, ORCID
Added: August 6, 2018

2018 journal article

Confirmation of high-throughput screening data and novel mechanistic insights into VDR-xenobiotic interactions by orthogonal assays

Scientific Reports, 8(1).

By: D. Mahapatra n, J. Franzosa*, K. Roell n, M. Kuenemann n, K. Houck*, D. Reif n, D. Fourches n, S. Kullman n

co-author countries: United States of America 🇺🇸

Contributors: D. Mahapatra n, J. Franzosa*, K. Roell n, M. Kuenemann n, K. Houck*, D. Reif n, D. Fourches n, S. Kullman n

MeSH headings : Drug Evaluation, Preclinical; Genes, Reporter; High-Throughput Screening Assays; Humans; Luciferases / analysis; Luciferases / genetics; Protein Binding; Receptors, Calcitriol / agonists; Receptors, Calcitriol / antagonists & inhibitors; Two-Hybrid System Techniques; Xenobiotics / metabolism
Sources: Crossref, ORCID, NC State University Libraries
Added: August 6, 2018

2018 journal article

Maternal vitamin D, DNA methylation at imprint regulatory regions and offspring weight at birth, 1 year and 3 years

INTERNATIONAL JOURNAL OF OBESITY, 42(4), 587–593.

By: S. Neelon*, A. White*, A. Vidal*, J. Schildkraut*, A. Murtha*, S. Murphy*, S. Kullman n, C. Hoyo n

co-author countries: United States of America 🇺🇸
MeSH headings : Adult; Birth Weight / physiology; Child, Preschool; DNA Methylation / genetics; Female; Genomic Imprinting / genetics; Humans; Infant; Infant, Newborn; Mothers; Pregnancy; Prospective Studies; Socioeconomic Factors; Vitamin D / blood; Young Adult
Sources: Web Of Science, ORCID
Added: August 6, 2018

2018 chapter

Nuclear receptors

In R. C. Smart & E. Hodgson (Eds.), Molecular and Biochemical Toxicology (5th ed., pp. 293–326). Hoboken, NJ: John Wiley & Sons.

By: S. Kullman, W. Baldwin & G. LeBlanc

Ed(s): R. Smart & E. Hodgson

Source: NC State University Libraries
Added: September 15, 2022

2018 article

Predicting characteristics of rainfall driven estrogen runoff and transport from swine AFO spray fields (vol 532, pg 571, 2015)

Lee, B., Kullman, S. W., Yost, E. E., Meyer, M. T., Worley-Davis, L., Williams, C. M., & Reckhow, K. H. (2018, July 1). SCIENCE OF THE TOTAL ENVIRONMENT, Vol. 628-629, pp. 1460–1460.

By: B. Lee*, S. Kullman n, E. Yost n, M. Meyer*, L. Worley-Davis n, C. Williams n, K. Reckhow*

co-author countries: United States of America 🇺🇸
Sources: Web Of Science, ORCID
Added: August 6, 2018

2018 journal article

Relation of contaminants to fish intersex in riverine sport fishes

Science of The Total Environment, 643, 73–89.

By: C. Grieshaber n, T. Penland n, T. Kwak n, W. Cope n, R. Heise*, J. Law n, D. Shea n, D. Aday n ...

co-author countries: United States of America 🇺🇸

Contributors: C. Grieshaber n, T. Penland n, T. Kwak n, W. Cope n, R. Heise*, J. Law n, D. Shea n, D. Aday n, J. Rice n, S. Kullman n

author keywords: Endocrine active compounds; Endocrine disruption; Bass; Polycyclic aromatic hydrocarbons; Ethinylestradiol; Mercury
MeSH headings : Animals; Disorders of Sex Development / epidemiology; Disorders of Sex Development / veterinary; Environmental Monitoring; Female; Fish Diseases / epidemiology; Fishes / physiology; Male; North Carolina; Rivers / chemistry; South Carolina; Sports; Water Pollutants, Chemical / analysis; Water Pollution, Chemical / statistics & numerical data
Sources: Web Of Science, ORCID, Crossref
Added: October 16, 2018

2017 journal article

Endocrine active contaminants in aquatic systems and intersex in common sport fishes

Environmental Toxicology and Chemistry, 36(4), 959–968.

By: C. Lee Pow n, J. Law n, T. Kwak n, W. Cope n, J. Rice n, S. Kullman n, D. Aday n

co-author countries: United States of America 🇺🇸
author keywords: Intersex; Estrogens; Endocrine disruption; Black bass; Sunfish
MeSH headings : Animals; Bass / growth & development; Bass / metabolism; Disorders of Sex Development / chemically induced; Endocrine Disruptors / analysis; Endocrine Disruptors / toxicity; Endocrine System / drug effects; Environmental Monitoring; Female; Male; North Carolina; Oocytes / drug effects; Oocytes / growth & development; Rivers / chemistry; Seasons; Species Specificity; Sports; Testis / drug effects; Testis / growth & development; Water Pollutants, Chemical / analysis; Water Pollutants, Chemical / toxicity
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018

2017 journal article

Exposure to a PBDE/OH-BDE mixture alters juvenile zebrafish (Danio rerio) development

ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY, 36(1), 36–48.

By: L. Macaulay*, M. Chernick*, A. Chen*, D. Hinton*, J. Bailey*, S. Kullman n, E. Levin*, H. Stapleton*

co-author countries: United States of America 🇺🇸
author keywords: Polybrominated diphenyl ether (PBDE); Mixture; Development; Juvenile; Zebrafish
MeSH headings : Adult; Animals; Dose-Response Relationship, Drug; Gene Expression / drug effects; Halogenated Diphenyl Ethers / metabolism; Halogenated Diphenyl Ethers / toxicity; Humans; Osteogenesis / drug effects; Osteogenesis / genetics; Polybrominated Biphenyls / metabolism; Polybrominated Biphenyls / toxicity; Thyroid Gland / drug effects; Thyroid Gland / metabolism; Thyroid Hormones / genetics; Thyroid Hormones / metabolism; Zebrafish / genetics; Zebrafish / growth & development; Zebrafish / metabolism
Sources: Web Of Science, ORCID
Added: August 6, 2018

2017 journal article

Windows of Susceptibility and Consequences of Early Life Exposures to 17β–estradiol on Medaka (Oryzias latipes) Reproductive Success

Environmental Science & Technology, 51(9), 5296–5305.

By: C. Lee Pow n, K. Tilahun n, K. Creech n, J. Law n, W. Cope n, T. Kwak n, J. Rice n, D. Aday n, S. Kullman n

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Estradiol / pharmacology; Gonads / drug effects; Oryzias; Reproduction / drug effects; Sex Differentiation / drug effects
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018

2016 journal article

Advancing toxicology research using in vivo high throughput toxicology with small fish models

ALTEX - Alternatives to Animal Experimentation, 33(4), 435–452.

By: A. Planchart n, C. Mattingly n, D. Allen*, P. Ceger*, W. Casey*, D. Hinton*, J. Kanungo*, S. Kullman n ...

co-author countries: United States of America 🇺🇸

Contributors: A. Planchart n, C. Mattingly n, D. Allen*, P. Ceger*, W. Casey*, D. Hinton*, J. Kanungo*, S. Kullman n ...

author keywords: aquatic models; 21st century toxicology; alternatives
Sources: Crossref, ORCID, NC State University Libraries
Added: August 6, 2018

2016 journal article

Evolutionary and Functional Diversification of the Vitamin D Receptor-Lithocholic Acid Partnership

PLOS ONE, 11(12).

By: E. Kollitz n, G. Zhang n, M. Hawkins n, G. Whitfield*, D. Reif n & S. Kullman n

co-author countries: United States of America 🇺🇸

Contributors: E. Kollitz n, G. Zhang n, M. Hawkins n, G. Whitfield*, D. Reif n & S. Kullman n

Ed(s): C. Zhang n

MeSH headings : Animals; Biological Evolution; Hep G2 Cells; Humans; Lithocholic Acid / metabolism; Receptors, Calcitriol / metabolism; Vertebrates
Sources: Web Of Science, ORCID
Added: August 6, 2018

2016 journal article

From the Cover: Embryonic Exposure to TCDD Impacts Osteogenesis of the Axial Skeleton in Japanese medaka,Oryzias latipes

Toxicological Sciences, 155(2), 485–496.

By: A. Watson*, A. Planchart n, C. Mattingly n, C. Winkler*, D. Reif n & S. Kullman n

co-author countries: Singapore 🇸🇬 United States of America 🇺🇸

Contributors: A. Watson, A. Planchart n, C. Mattingly n, C. Winkler*, D. Reif n & S. Kullman n

author keywords: receptor, aryl hydrocarbon; gene expression/regulation, bone; transgenic models; methods, developmental/teratology; reproductive and developmental toxicology
MeSH headings : Animals; Calcification, Physiologic / drug effects; Down-Regulation / drug effects; Microscopy, Confocal; Musculoskeletal Diseases / metabolism; Oryzias / embryology; Osteogenesis / drug effects; Polychlorinated Dibenzodioxins / toxicity; Real-Time Polymerase Chain Reaction; Skeleton / drug effects; Skeleton / metabolism; Trans-Activators / drug effects
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018

2016 journal article

Sharing the Roles: An Assessment of Japanese Medaka Estrogen Receptors in Vitellogenin Induction

ENVIRONMENTAL SCIENCE & TECHNOLOGY, 50(16), 8886–8895.

By: C. Pow n, E. Yost n, D. Aday n & S. Kullman n

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Biological Assay; Estradiol / metabolism; Estrogens / metabolism; Gene Expression / drug effects; Oryzias / metabolism; Receptors, Estrogen / metabolism; Up-Regulation / drug effects; Vitellogenins / metabolism
Sources: Web Of Science, ORCID
Added: August 6, 2018

2016 content posted

Where do we go from here: Challenges and the future of endocrine disrupting compound screening and testing

By: V. Wilson*, G. LeBlanc n, S. Kullman n, K. Crofton*, P. Schmieder* & M. Jacobs*

co-author countries: United Kingdom of Great Britain and Northern Ireland 🇬🇧 United States of America 🇺🇸
Sources: Crossref, ORCID
Added: November 11, 2019

2015 journal article

In Response : Conservation versus functional diversification of nuclear receptors: An academic perspective

Environmental Toxicology and Chemistry, 34(3), 463–465.

By: S. Kullman n

co-author countries: United States of America 🇺🇸
MeSH headings : Animals
Sources: Crossref, ORCID
Added: December 31, 2020

2015 journal article

Molecular Cloning, Functional Characterization, and Evolutionary Analysis of Vitamin D Receptors Isolated from Basal Vertebrates

PLOS ONE, 10(4).

By: E. Kollitz n, G. Zhang n, M. Hawkins n, G. Whitfield*, D. Reif n & S. Kullman n

co-author countries: United States of America 🇺🇸

Contributors: E. Kollitz n, G. Zhang n, M. Hawkins n, G. Whitfield*, D. Reif n & S. Kullman n

MeSH headings : Animals; Base Sequence; Cloning, Molecular; Computational Biology; Electrophoretic Mobility Shift Assay; Evolution, Molecular; Fishes / genetics; Likelihood Functions; Models, Genetic; Molecular Sequence Data; Petromyzon / genetics; Phylogeny; Protein Binding; Protein Interaction Mapping; Receptors, Calcitriol / genetics; Sequence Analysis, DNA; Skates, Fish / genetics; Species Specificity; Two-Hybrid System Techniques
Sources: Web Of Science, ORCID
Added: August 6, 2018

2015 journal article

Predicting characteristics of rainfall driven estrogen runoff and transport from swine AFO spray fields

SCIENCE OF THE TOTAL ENVIRONMENT, 532, 571–580.

By: B. Lee*, S. Kullman n, E. Yost n, M. Meyer*, L. Worley-Davis n, C. Williams n, K. Reckhow*

co-author countries: United States of America 🇺🇸
author keywords: Estrogen runoff and transport; Bayesian network model; Swine animal feeding operation; Spray fields
MeSH headings : Agriculture / methods; Animal Feed; Animals; Bayes Theorem; Environmental Monitoring / methods; Estrogens / analysis; Geologic Sediments; Manure; Models, Chemical; Rain; Soil / chemistry; Swine; Water Movements; Water Pollutants, Chemical / analysis; Water Pollution, Chemical / statistics & numerical data
Sources: Web Of Science, ORCID
Added: August 6, 2018

2015 journal article

Sources of endocrine-disrupting compounds in North Carolina waterways: A geographic information systems approach

Environmental Toxicology and Chemistry, 34(2), 437–445.

By: D. Sackett n, C. Pow n, M. Rubino n, D. Aday n, W. Cope n, S. Kullman n, J. Rice n, T. Kwak n, M. Law n

co-author countries: United States of America 🇺🇸
author keywords: Ecotoxicology; Endocrine disrupting compound; Estrogenicity; Geographic information system prediction; Surface water
MeSH headings : Endocrine Disruptors / analysis; Estradiol / analysis; Estrogens / analysis; Geographic Information Systems; Geography; Least-Squares Analysis; Models, Theoretical; North Carolina; Water Pollutants, Chemical / analysis
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018

2014 journal article

A Bayesian Network Model for Assessing Natural Estrogen Fate and Transport in a Swine Waste Lagoon

INTEGRATED ENVIRONMENTAL ASSESSMENT AND MANAGEMENT, 10(4), 511–521.

By: B. Lee*, S. Kullman n, E. Yost n, M. Meyer*, L. Worley-Davis n, C. Williams n, K. Reckhow*

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Bayes Theorem; Estrogens / chemistry; Models, Theoretical; Sewage / chemistry; Swine; Waste Disposal, Fluid; Water Pollutants, Chemical / chemistry
Sources: Web Of Science, ORCID
Added: August 6, 2018

2014 journal article

Bridging the Gap From Screening Assays to Estrogenic Effects in Fish: Potential Roles of Multiple Estrogen Receptor Subtypes

ENVIRONMENTAL SCIENCE & TECHNOLOGY, 48(9), 5211–5219.

By: E. Yost n, C. Pow n, M. Hawkins n & S. Kullman n

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Estrogen Receptor alpha / physiology; Estrogen Receptor beta / physiology; Estrogens / pharmacology; Humans; Liver / metabolism; Male; Oryzias; Polymerase Chain Reaction; Vitellogenins / metabolism; Water Pollutants, Chemical / pharmacology
Sources: Web Of Science, ORCID
Added: August 6, 2018

2014 journal article

Functional diversification of vitamin D receptor paralogs in teleost fish after a whole genome duplication event

Endocrinology, 155(12), 4641–4654.

By: E. Kollitz n, M. Hawkins n, G. Whitfield* & S. Kullmam

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Calcitriol / metabolism; Evolution, Molecular; Fish Proteins / genetics; Fish Proteins / metabolism; Gene Duplication; Genome; Nuclear Receptor Coactivators / metabolism; Oryzias; Receptors, Calcitriol / genetics; Receptors, Calcitriol / metabolism; Retinoid X Receptors / metabolism; Zebrafish
Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2014 journal article

Transport of Steroid Hormones, Phytoestrogens, and Estrogenic Activity across a Swine Lagoon/Sprayfield System

ENVIRONMENTAL SCIENCE & TECHNOLOGY, 48(19), 11600–11609.

By: E. Yost n, M. Meyer*, J. Dietze*, C. Williams n, L. Worley-Davis n, B. Lee*, S. Kullman n

co-author countries: United States of America 🇺🇸
MeSH headings : Agriculture / methods; Androgens / chemistry; Androstenedione / chemistry; Animals; Diet / veterinary; Environmental Monitoring / methods; Equol / chemistry; Estrogens / chemistry; Estrone / chemistry; Feces / chemistry; Genistein / chemistry; Hormones / chemistry; Isoflavones / chemistry; Phytoestrogens / chemistry; Progesterone / chemistry; Steroids / chemistry; Swine; Urine / chemistry
Sources: Web Of Science, ORCID
Added: August 6, 2018

2013 report

A Set of Scientific Issues Being Considered by the Environmental Protection Agency Regarding: Proposed Endocrine Disruptor Screening Program (EDSP) Tier 2 Ecotoxicity Tests

(SAP Minutes No. 2013-04). Environmental Protection Agency.

By: S. Kullman

Source: NC State University Libraries
Added: September 16, 2022

2013 journal article

Comprehensive Assessment of Hormones, Phytoestrogens, and Estrogenic Activity in an Anaerobic Swine Waste Lagoon

ENVIRONMENTAL SCIENCE & TECHNOLOGY, 47(23), 13781–13790.

By: E. Yost n, M. Meyer*, J. Dietze*, B. Meissner*, L. Worley-Davis n, C. Williams n, B. Lee*, S. Kullman n

co-author countries: United States of America 🇺🇸
MeSH headings : Anaerobiosis; Animals; Chromatography, Liquid; Estrogens / analysis; Mass Spectrometry; Phytoestrogens / analysis; Sewage / chemistry; Swine; Wastewater / chemistry; Water Pollutants, Chemical / analysis
Sources: Web Of Science, ORCID
Added: August 6, 2018

2013 journal article

Immunohistochemical characterization of the hepatic progenitor cell compartment in medaka (oryzias latipes) following hepatic injury

Journal of Comparative Pathology, 149(4), 434–445.

By: A. Wettere n, S. Kullmam, D. Hinton* & J. Law n

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Animals, Genetically Modified; Cell Differentiation / physiology; Disease Models, Animal; Female; Hepatocytes / cytology; Hepatocytes / ultrastructure; Immunohistochemistry; Liver / injuries; Liver Regeneration / physiology; Male; Microscopy, Electron, Transmission; Oryzias; Stem Cells / cytology; Stem Cells / ultrastructure
Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2013 journal article

Phenotypic Characterization of Transgenic Japanese Medaka (Oryzias latipes) That Express a Red Fluorescent Protein in Hepatocytes

Toxicologic Pathology, 42(3), 616–621.

By: A. Van Wettere n, J. Law n, D. Hinton* & S. Kullman n

co-author countries: United States of America 🇺🇸
author keywords: transgenic medaka; Oryzias latipes; liver fatty acid binding protein; inclusion; red fluorescent protein
MeSH headings : Animals; Animals, Genetically Modified / genetics; Animals, Genetically Modified / metabolism; Cloning, Molecular; Embryo, Nonmammalian; Fatty Acid-Binding Proteins / genetics; Female; Hepatocytes / chemistry; Hepatocytes / metabolism; Liver / chemistry; Liver / metabolism; Luminescent Proteins / chemistry; Luminescent Proteins / genetics; Luminescent Proteins / metabolism; Male; Oryzias / genetics; Oryzias / metabolism; Phenotype
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018

2012 journal article

Anchoring Ethinylestradiol Induced Gene Expression Changes with Testicular Morphology and Reproductive Function in the Medaka

PLOS ONE, 7(12).

By: H. Miller*, B. Clark*, D. Hinton*, A. Whitehead*, S. Martin n, K. Kwok*, S. Kullman n

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Breeding; Estrogens / toxicity; Ethinyl Estradiol / toxicity; Male; Oligonucleotide Array Sequence Analysis; Oryzias / anatomy & histology; Oryzias / genetics; Oryzias / physiology; Reproduction / drug effects; Reproduction / genetics; Species Specificity; Testis / anatomy & histology; Testis / drug effects; Testis / metabolism; Testis / physiology; Time Factors; Transcriptome / drug effects
Sources: Web Of Science, ORCID
Added: August 6, 2018

2012 journal article

Anchoring hepatic gene expression with development of fibrosis and neoplasia in a toxicant-induced fish model of liver injury

Toxicologic Pathology, 41(5), 1–17.

By: A. Van Wettere n, J. Law n, D. Hinton* & S. Kullman n

co-author countries: United States of America 🇺🇸
author keywords: dimethylnitrosamine; liver; fibrosis; neoplasia; medaka; Oryzias latipes; gene expression
MeSH headings : Animals; Chemical and Drug Induced Liver Injury / etiology; Chemical and Drug Induced Liver Injury / genetics; Chemical and Drug Induced Liver Injury / metabolism; Chemical and Drug Induced Liver Injury / pathology; Dimethylnitrosamine / toxicity; Disease Models, Animal; Female; Fish Proteins / chemistry; Fish Proteins / genetics; Fish Proteins / metabolism; Gene Expression; Immunohistochemistry; Liver / drug effects; Liver / metabolism; Liver / pathology; Liver Cirrhosis / chemically induced; Liver Cirrhosis / genetics; Liver Cirrhosis / metabolism; Liver Cirrhosis / pathology; Male; Microscopy, Electron, Transmission; Oryzias; Phenotype
Sources: Web Of Science, ORCID
Added: August 6, 2018

2012 journal article

Comparative Genomics of Duplicate gamma-Glutamyl Transferase Genes in Teleosts: Medaka (Oryzias latipes), Stickleback (Gasterosteus aculeatus), Green Spotted Pufferfish (Tetraodon nigroviridis), Fugu (Takifugu rubripes), and Zebrafish (Danio rerio)

JOURNAL OF EXPERIMENTAL ZOOLOGY PART B-MOLECULAR AND DEVELOPMENTAL EVOLUTION, 318B(1), 35–49.

By: S. Law n, B. Redelings n & S. Kullman n

co-author countries: United States of America 🇺🇸
MeSH headings : Amino Acid Sequence; Animals; Female; Fishes / classification; Fishes / genetics; Gene Expression Profiling; Gene Expression Regulation, Developmental; Genes, Duplicate / genetics; Genomics; Larva; Male; Molecular Sequence Data; Phylogeny; Sequence Alignment; Synteny; gamma-Glutamyltransferase / chemistry; gamma-Glutamyltransferase / genetics
Sources: Web Of Science, ORCID
Added: August 6, 2018

2012 book

Detailed Review Paper on the State of the Science on Novel In Vitro and In Vivo Screening and Testing Methods and Endpoints for Evaluating Endocrine Disruptors

In OECD Series on Testing and Assessment.

Seth Kullman

Sources: Crossref, ORCID
Added: September 15, 2022

2012 journal article

TCDD Disrupts Hypural Skeletogenesis during Medaka Embryonic Development

TOXICOLOGICAL SCIENCES, 125(1), 91–104.

By: W. Dong n, D. Hinton* & S. Kullman n

co-author countries: China 🇨🇳 United States of America 🇺🇸
author keywords: medaka; dioxin; cartilage; skeletogenesis; aquatic toxicology
MeSH headings : Animals; Cartilage / abnormalities; Cartilage / drug effects; Cartilage / embryology; Cartilage / ultrastructure; Cell Differentiation / drug effects; Cell Proliferation / drug effects; Chondrocytes / drug effects; Chondrocytes / ultrastructure; Collagen Type II / genetics; Dose-Response Relationship, Drug; Embryo, Nonmammalian / abnormalities; Embryo, Nonmammalian / drug effects; Embryo, Nonmammalian / pathology; Gene Expression / drug effects; Mesenchymal Stem Cells / drug effects; Mesenchymal Stem Cells / ultrastructure; Microscopy, Electron, Transmission; Musculoskeletal Abnormalities / chemically induced; Musculoskeletal Abnormalities / embryology; Musculoskeletal Abnormalities / pathology; Oryzias / abnormalities; Oryzias / embryology; Osteogenesis / drug effects; Polychlorinated Dibenzodioxins / toxicity; Real-Time Polymerase Chain Reaction
Sources: Web Of Science, ORCID
Added: August 6, 2018

2011 journal article

The evolution of farnesoid X, vitamin D, and pregnane X receptors: insights from the green-spotted pufferfish (Tetraodon nigriviridis) and other non-mammalian species

BMC BIOCHEMISTRY, 12.

By: M. Krasowski*, N. Ai, L. Hagey*, E. Kollitz n, S. Kullman n, E. Reschly*, S. Ekins*

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Bile Acids and Salts / metabolism; Evolution, Molecular; Humans; Ligands; Mice; Models, Molecular; Pregnane X Receptor; Protein Interaction Domains and Motifs; Rats; Receptors, Calcitriol / genetics; Receptors, Calcitriol / metabolism; Receptors, Cytoplasmic and Nuclear / genetics; Receptors, Cytoplasmic and Nuclear / metabolism; Receptors, Steroid / genetics; Receptors, Steroid / metabolism; Species Specificity; Structure-Activity Relationship; Tetraodontiformes; Zebrafish
Sources: Web Of Science, ORCID
Added: August 6, 2018

2010 journal article

Exposure to the synthetic FXR agonist GW4064 causes alterations in gene expression and sublethal hepatotoxicity in eleutheroembryo medaka (Oryzias latipes)

TOXICOLOGY AND APPLIED PHARMACOLOGY, 243(1), 111–121.

By: D. Howarth*, S. Law n, J. Law n, J. Mondon*, S. Kullman n & D. Hinton*

co-author countries: United States of America 🇺🇸
author keywords: Farnesoid X receptor; Liver; Medaka; Toxicity; Eleutheroembryo
MeSH headings : Animals; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Embryo, Nonmammalian / drug effects; Embryo, Nonmammalian / physiology; Female; Gene Expression Regulation, Developmental / drug effects; Isoxazoles / pharmacology; Liver / drug effects; Liver / pathology; Liver / ultrastructure; Male; Oryzias / embryology; Protein Isoforms; Receptors, Cytoplasmic and Nuclear / agonists; Yolk Sac
Sources: Web Of Science, ORCID
Added: August 6, 2018

2010 chapter

Perspectives on Informatics in Toxicology, in A Textbook of Modern Toxicology

In E. Hodgson (Ed.), A Textbook of Modern Toxicology (4th ed., pp. 593–605). Hoboken NJ: John Wiley and Sons.

By: S. Kullman, C. Mattingly, J. Meyer & A. Whitehead

Ed(s): E. Hodgson

Source: NC State University Libraries
Added: September 16, 2022

2010 journal article

TCDD Induced Pericardial Edema and Relative COX-2 Expression in Medaka (Oryzias Latipes) Embryos

TOXICOLOGICAL SCIENCES, 118(1), 213–223.

By: W. Dong n, F. Matsumura* & S. Kullman n

co-author countries: United States of America 🇺🇸
author keywords: COX-2; TCDD; medaka; pericardial edema
MeSH headings : Animals; Arachidonic Acid / pharmacology; Cyclooxygenase 2 / biosynthesis; Cyclooxygenase 2 / genetics; Cyclooxygenase Inhibitors / pharmacology; Embryo, Nonmammalian / abnormalities; Embryo, Nonmammalian / drug effects; Embryo, Nonmammalian / enzymology; Gene Expression Regulation, Developmental / drug effects; Gene Silencing; Nitrobenzenes / pharmacology; Oryzias / physiology; Pericardial Effusion / chemically induced; Pericardial Effusion / genetics; Pericardial Effusion / pathology; Polychlorinated Dibenzodioxins / toxicity; RNA, Messenger / metabolism; Sulfonamides / pharmacology; Teratogens / toxicity
Sources: Web Of Science, ORCID
Added: August 6, 2018

2010 journal article

Two farnesoid X receptor alpha isoforms in Japanese medaka (Oryzias latipes) are differentially activated in vitro

Aquatic Toxicology (Amsterdam, Netherlands), 98(3), 245–255.

By: D. Howarth*, L. Hagey*, S. Law n, N. Ai, M. Krasowski*, S. Ekins*, J. Moore*, E. Kollitz n, D. Hinton*, S. Kullmam

co-author countries: United States of America 🇺🇸
MeSH headings : Amino Acid Sequence; Animals; Base Sequence; Bile Acids and Salts / pharmacology; Binding Sites; Fresh Water; Genes, Reporter / genetics; Humans; Molecular Sequence Data; Oryzias / genetics; Protein Isoforms / genetics; Protein Isoforms / metabolism; Receptors, Cytoplasmic and Nuclear / genetics; Receptors, Cytoplasmic and Nuclear / metabolism; Titrimetry; Transcriptional Activation / drug effects; Transcriptional Activation / genetics; Transfection
Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2009 journal article

Aquatic animal models of human disease: Selected papers and recommendations from the 4th Conference

Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology, 149(2), 121–128.

By: D. Hinton*, R. Hardman*, S. Kullman n, J. Law n, M. Schmale*, R. Walter*, R. Winn*, J. Yoder n

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Disease Models, Animal; Fishes; Humans; Mollusca
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018

2009 journal article

Use of Medaka in Toxicity Testing

Current Protocols in Toxicology, 39(1).

By: S. Padilla*, J. Cowden*, D. Hinton*, B. Yuen*, S. Law*, S. Kullman n, R. Johnson*, R. Hardman*, K. Flynn*, D. Au*

co-author countries: Hong Kong 🇭🇰 United States of America 🇺🇸
MeSH headings : Animals; Biliary Tract / drug effects; Biliary Tract / pathology; Embryo, Nonmammalian / drug effects; Embryo, Nonmammalian / pathology; Female; Liver / drug effects; Liver / pathology; Male; Models, Animal; Nervous System / drug effects; Oryzias / embryology; Oryzias / growth & development; Oryzias / physiology; Toxicity Tests / methods
Sources: Crossref, ORCID
Added: September 13, 2022

2008 chapter

Biotransformation in Fishes

In The Toxicology of Fishes (pp. 153–234).

By: D. Schlenk, M. Celander, E. Gallagher, S. George, M. James, S. Kullman*, P. van den Hurk, K. Willett

Sources: Crossref, ORCID
Added: September 15, 2022

2008 article

Differential developmental toxicity of naphthoic acid isomers in medaka (Oryzias latipes) embryos

MARINE POLLUTION BULLETIN, Vol. 57, pp. 255–266.

By: M. Carney*, K. Erwin*, R. Hardman*, B. Yuen*, D. Volz*, D. Hinton*, S. Kullman n

co-author countries: United States of America 🇺🇸
author keywords: naphthoic acid; PAH metabolites; medaka; embryo toxicity; tube heart; EROD; eleutheroembryos
MeSH headings : Animals; Carboxylic Acids / toxicity; Cell Line; Cytochrome P-450 CYP1A1 / genetics; Cytochrome P-450 CYP1A1 / metabolism; Embryo, Nonmammalian / drug effects; Embryo, Nonmammalian / enzymology; Embryonic Development / drug effects; Gene Expression Regulation, Developmental / drug effects; Heart Rate / drug effects; Hydrogen-Ion Concentration; Isomerism; Lethal Dose 50; Linear Models; Mice; Naphthalenes / toxicity; Oryzias / embryology; Receptors, Aryl Hydrocarbon / drug effects; Receptors, Aryl Hydrocarbon / metabolism; Time Factors; Transcriptional Activation / drug effects; Water Pollutants, Chemical / toxicity
Sources: Web Of Science, ORCID
Added: August 6, 2018

2008 report

Endocrine Disruptor Screening Program (EDSP) Proposed Tier 1 Screening Battery - Federal Insecticide, Fungicide, and Rodenticide Act Scientific Advisory Panel

Environmental Protection Agency.

By: S. Kullman

Source: NC State University Libraries
Added: September 16, 2022

2008 chapter

Liver Toxicity

In The Toxicology of Fishes (pp. 327–400).

By: D. Hinton, H. Segner, D. Au, S. Kullman* & R. Hardman

Sources: Crossref, ORCID
Added: September 15, 2022

2008 journal article

Non invasive high resolution in vivo imaging of α-naphthylisothiocyanate (ANIT) induced hepatobiliary toxicity in STII medaka

Aquatic Toxicology, 86(1), 20–37.

By: R. Hardman*, S. Kullman*, B. Yuen* & D. Hinton*

co-author countries: United States of America 🇺🇸
author keywords: fish; toxicology; hepatobiliary; liver; toxicity; medaka; ANIT; biliary; biliary toxicity; alpha-naphthylisothiocyanate; hepatotoxicity; piscine liver
MeSH headings : 1-Naphthylisothiocyanate / toxicity; Animals; Antibodies / metabolism; Apoptosis; Bile Ducts, Intrahepatic / drug effects; Bile Ducts, Intrahepatic / pathology; Bile Ducts, Intrahepatic / ultrastructure; Blood Vessels / drug effects; Epithelial Cells / cytology; Epithelial Cells / drug effects; Fluorescent Dyes / analysis; Image Processing, Computer-Assisted; Imaging, Three-Dimensional / veterinary; Liver / blood supply; Liver / drug effects; Liver / pathology; Liver / ultrastructure; Microscopy, Confocal / veterinary; Models, Animal; Oryzias / genetics; Oryzias / physiology; Phenotype
Sources: Crossref, ORCID
Added: August 28, 2020

2008 journal article

Non invasive in vivo investigation of hepatobiliary structure and function in STII medaka (Oryzias latipes): methodology and applications

Comparative Hepatology, 7(1).

By: R. Hardman*, S. Kullman* & D. Hinton*

co-author countries: United States of America 🇺🇸
Sources: Crossref, ORCID
Added: September 13, 2022

2008 journal article

Paralogous vitamin D receptors in teleosts: Transition of nuclear receptor function

ENDOCRINOLOGY, 149(5), 2411–2422.

By: D. Howarth*, S. Law n, B. Barnes*, J. Hall*, D. Hinton*, L. Moore*, J. Maglich*, J. Moore*, S. Kullman n

co-author countries: United States of America 🇺🇸
MeSH headings : Amino Acid Sequence; Animals; Cells, Cultured; Cloning, Molecular; Cricetinae; Cricetulus; Evolution, Molecular; Female; Fishes / genetics; Humans; Male; Molecular Sequence Data; Oryzias / genetics; Phylogeny; Receptors, Calcitriol / genetics; Receptors, Calcitriol / metabolism; Receptors, Calcitriol / physiology; Receptors, Cytoplasmic and Nuclear / physiology; Sequence Homology, Amino Acid; Tissue Distribution; Trans-Activators / metabolism
Sources: Web Of Science, ORCID
Added: August 6, 2018

2008 journal article

Protective response of the ah receptor to ANIT-Induced biliary epithelial cell toxicity in see-through medaka

TOXICOLOGICAL SCIENCES, 102(2), 262–277.

By: D. Volz, S. Kullman*, D. Howarth, R. Hardman & D. Hinton

author keywords: see-through medaka; AHR; liver; nuclear receptor; bile; ANIT
MeSH headings : 1-Naphthylisothiocyanate / toxicity; Animals; Apoptosis / drug effects; Bile Ducts, Intrahepatic / drug effects; Bile Ducts, Intrahepatic / metabolism; Bile Ducts, Intrahepatic / pathology; Bilirubin / pharmacology; Cell Line, Tumor; Cholestasis, Intrahepatic / metabolism; Cholestasis, Intrahepatic / prevention & control; Cloning, Molecular; Cytochrome P-450 CYP1A1 / biosynthesis; Cytochrome P-450 CYP1A1 / genetics; Disease Models, Animal; Drug Antagonism; Enzyme Induction; Epithelial Cells / drug effects; Epithelial Cells / metabolism; Epithelial Cells / ultrastructure; Gallbladder / drug effects; Gallbladder / pathology; Gene Expression / drug effects; Injections, Intraperitoneal; Liver / drug effects; Liver / metabolism; Liver / pathology; Male; Mice; Oryzias / physiology; Pigmentation / genetics; Polychlorinated Dibenzodioxins / pharmacology; RNA, Messenger / metabolism; Receptors, Aryl Hydrocarbon / agonists; Receptors, Aryl Hydrocarbon / drug effects; Receptors, Aryl Hydrocarbon / metabolism
Sources: Web Of Science, ORCID
Added: August 6, 2018

2007 journal article

An in vivo Look at Vertebrate Liver Architecture: Three-Dimensional Reconstructions from Medaka (Oryzias latipes)

The Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology, 290(7), 770–782.

By: R. Hardman*, D. Volz*, S. Kullman* & D. Hinton*

co-author countries: United States of America 🇺🇸
author keywords: liver; hepatobiliary; biliary; liver architecture; comparative hepatology; fish; 3-dimensional structure; liver structure and function
MeSH headings : Animals; Biliary Tract / cytology; Biliary Tract / ultrastructure; Computer Simulation; Epithelial Cells / ultrastructure; Fluorescent Dyes; Hepatocytes / ultrastructure; Imaging, Three-Dimensional; Liver / blood supply; Liver / cytology; Liver / ultrastructure; Microscopy, Confocal; Microscopy, Electron, Transmission; Models, Anatomic; Oryzias / anatomy & histology
Sources: Crossref, ORCID
Added: August 28, 2020

2007 journal article

Application of in vivo methodologies to investigation biological structure, function and xenobiotic response in see-through medaka (Oryzias latipes

The Fish Biology Journal, Medaka, 11, 43–65.

By: R. Hardman, S. Kullman & D. Hinton

Source: NC State University Libraries
Added: September 16, 2022

2007 report

Bioanalytical Analysis Of Natural Estrogens at Concentrated Animal Feed Operations Affecting North Carolina River Waters

(No. 376). Water Resources Research Institute of North Carolina.

By: S. Kullman, K. Linden & D. Hinton

Source: NC State University Libraries
Added: September 16, 2022

2007 journal article

Biological assessments of a mixture of endocrine disruptors at environmentally relevant concentrations in water following UV/H2O2 oxidation

Science of The Total Environment, 376(1-3), 18–26.

By: P. Chen*, E. Rosenfeldt*, S. Kullman*, D. Hinton* & K. Linden*

co-author countries: United States of America 🇺🇸
author keywords: endocrine disrupting compounds (EDCs); UV/H2O2 oxidation process; yeast estrogen screen (YES); vitellogenin (VTG)
MeSH headings : Animals; Benzhydryl Compounds; Drug Interactions; Endocrine Disruptors / toxicity; Estradiol / toxicity; Estrogens / toxicity; Ethinyl Estradiol / toxicity; Hydrogen Peroxide / chemistry; Male; Oryzias / metabolism; Oxidants / chemistry; Oxidation-Reduction; Phenols / toxicity; Photolysis; Receptors, Estrogen / metabolism; Rivers; Ultraviolet Rays; Vitellogenins / biosynthesis; Water Pollutants, Chemical / toxicity; Water Purification / methods; Yeasts / metabolism
Sources: Crossref, ORCID
Added: August 28, 2020

2007 journal article

Comparisons of polychromatic and monochromatic UV-based treatments of bisphenol-A in water via toxicity assessments

Chemosphere, 68(6), 1041–1049.

By: P. Chen*, S. Kullman*, D. Hinton* & K. Linden*

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Benzhydryl Compounds; Embryo, Nonmammalian / drug effects; Endocrine Disruptors / analysis; Endocrine Disruptors / radiation effects; Endocrine Disruptors / toxicity; Hydrogen Peroxide / chemistry; Oryzias; Oxidation-Reduction / radiation effects; Phenols / analysis; Phenols / radiation effects; Phenols / toxicity; Photolysis / radiation effects; Ultraviolet Rays; Waste Disposal, Fluid / methods
Sources: Crossref, ORCID
Added: August 28, 2020

2007 journal article

Destruction of estrogenic activity in water using UV advanced oxidation

Science of The Total Environment, 377(1), 105–113.

By: E. Rosenfeldt*, P. Chen*, S. Kullman* & K. Linden*

co-author countries: United States of America 🇺🇸
author keywords: ultraviolet; water treatment; AOP; YES; endocrine disrupter; kinetics; model
MeSH headings : Endocrine Disruptors / analysis; Endocrine Disruptors / radiation effects; Estrogens, Non-Steroidal / analysis; Estrogens, Non-Steroidal / radiation effects; Oxidation-Reduction; Ultraviolet Rays; Water Pollutants, Chemical / analysis; Water Pollutants, Chemical / radiation effects; Water Purification / methods
Sources: Crossref, ORCID
Added: August 28, 2020

2007 journal article

Estrogenic modulation of CYP3A38, CYP3A40, and CYP19 in mature male medaka (Oryzias latipes)

Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology, 145(3), 370–378.

By: S. Kashiwada*, M. Kameshiro*, H. Tatsuta*, Y. Sugaya*, S. Kullman*, D. Hinton*, K. Goka*

co-author countries: Japan 🇯🇵 United States of America 🇺🇸
author keywords: CYP19; CYP3A; endocrine-disruption; estrogenic modulation; medaka; testosterone
MeSH headings : Animals; Aromatase / biosynthesis; Aromatase / genetics; Cytochrome P-450 CYP3A / biosynthesis; Cytochrome P-450 CYP3A / genetics; Dose-Response Relationship, Drug; Estradiol / pharmacology; Ethinyl Estradiol / pharmacology; Male; Oryzias / metabolism; RNA, Messenger / analysis; Testosterone / metabolism; Vitellogenins / biosynthesis
Sources: Crossref, ORCID
Added: August 28, 2020

2007 report

Impact of UV and UV Endocrine Disrupting Compounds in Water

(No. 91175). American Water Works Association Research Foundation.

By: K. Linden & S. Kullman

Source: NC State University Libraries
Added: September 16, 2022

2007 report

Towards an Innovative DNA Array Technology for Detection of Pharmaceuticals in Reclaimed Water

Water Environment Research Foundation (WERF) and Environmental Protection agency (EPA).

By: S. Kullman, K. Linden & D. Hinton

Source: NC State University Libraries
Added: September 16, 2022

2007 journal article

UV/H2O2 degradation of endocrine-disrupting chemicals in water evaluated via toxicity assays

Water Science and Technology, 55(12), 313–319.

By: K. Linden*, E. Rosenfeldt* & S. Kullman*

co-author countries: United States of America 🇺🇸
author keywords: endocrine disrupting compounds; estrogenic activity; UV photochemistry; UV/H2O2 advanced oxidation processes
MeSH headings : Endocrine Disruptors / chemistry; Endocrine Disruptors / radiation effects; Endocrine Disruptors / toxicity; Estradiol / analogs & derivatives; Estradiol / chemistry; Estradiol / toxicity; Hydrogen Peroxide / chemistry; Hydroxyl Radical / chemistry; Oxidation-Reduction; Saccharomyces cerevisiae / drug effects; Toxicity Tests / methods; Ultraviolet Rays; Water Purification / methods
Sources: Crossref, ORCID
Added: September 13, 2022

2006 journal article

Biological assessment of bisphenol A degradation in water following direct photolysis and UV advanced oxidation

Chemosphere, 65(7), 1094–1102.

By: P. Chen*, K. Linden*, D. Hinton*, S. Kashiwada*, E. Rosenfeldt* & S. Kullman*

co-author countries: United States of America 🇺🇸
author keywords: endocrine disrupting compounds (EDCs); low-pressure (LP) HgUV lamps; yeast estrogen screen (YES); vitellogenin (VTG); medaka (Oryzias latipes)
MeSH headings : Animals; Benzhydryl Compounds; Estrogen Receptor alpha / metabolism; Estrogens / metabolism; Estrogens / toxicity; Hydrogen Peroxide / chemistry; Larva / drug effects; Male; Oryzias; Oxidation-Reduction; Phenols / chemistry; Phenols / radiation effects; Phenols / toxicity; Photolysis; Ultraviolet Rays; Vitellogenins / metabolism; Water Pollutants, Chemical / chemistry; Water Pollutants, Chemical / radiation effects; Water Pollutants, Chemical / toxicity; Water Purification / methods; Yeasts / drug effects; Yeasts / metabolism
Sources: Crossref, ORCID
Added: August 28, 2020

2006 journal article

Dynamic Gene Expression Changes Precede Dioxin-Induced Liver Pathogenesis in Medaka Fish

Toxicological Sciences, 89(2), 524–534.

By: D. Volz, D. Hinton, J. Law & S. Kullman*

author keywords: medaka; dioxin; liver; aryl hydrocarbon receptor; gene expression; transcription
MeSH headings : Animals; Cytochrome P-450 CYP1A1 / genetics; Cytochrome P-450 CYP1A2 / genetics; Dose-Response Relationship, Drug; Gene Expression / drug effects; Gene Expression Profiling; Injections, Intraperitoneal; Liver / drug effects; Liver / metabolism; Liver / pathology; Male; Oligonucleotide Array Sequence Analysis; Oryzias; Polychlorinated Dibenzodioxins / toxicity; Receptors, Aryl Hydrocarbon / genetics; Reverse Transcriptase Polymerase Chain Reaction; Time Factors
Sources: Crossref, ORCID, Web Of Science
Added: August 6, 2018

2005 journal article

2,3,7,8-Tetrachlorodibenzo-p-Dioxin (TCDD) Induces Organ- Specific Differential Gene Expression in Male Japanese Medaka (Oryzias latipes)

Toxicological Sciences, 85(1), 572–584.

By: D. Volz*, D. Bencic, D. Hinton, J. Law & S. Kullman*

co-author countries: United States of America 🇺🇸
author keywords: Japanese medaka; TCDD; gene expression; brain; liver; testis
MeSH headings : Animals; Brain / drug effects; Brain / metabolism; Brain / pathology; Environmental Pollutants / toxicity; Gene Expression / drug effects; Gene Expression Profiling; Injections, Intraperitoneal; Liver / drug effects; Liver / metabolism; Liver / pathology; Male; Oligonucleotide Array Sequence Analysis; Organ Specificity; Oryzias / genetics; Polychlorinated Dibenzodioxins / toxicity; Reverse Transcriptase Polymerase Chain Reaction; Testis / drug effects; Testis / metabolism; Testis / pathology
Sources: Crossref, ORCID, Web Of Science
Added: August 6, 2018

2005 journal article

Functional characterization of medaka CYP3A38 and CYP3A40: Kinetics and catalysis by expression in a recombinant baculovirus system

Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology, 141(4), 338–348.

By: S. Kashiwada*, D. Hinton* & S. Kullman*

co-author countries: Japan 🇯🇵 United States of America 🇺🇸
author keywords: medaka; CYP3A; baculovirus; cytochrome P450; kinetics; testosterone; BFC; metabolism
MeSH headings : Amino Acid Sequence; Animals; Baculoviridae / genetics; Catalysis; Cytochrome P-450 CYP3A / chemistry; Cytochrome P-450 CYP3A / metabolism; Kinetics; Molecular Sequence Data; Oryzias / metabolism; Oxazines / metabolism; Recombinant Proteins / metabolism; Testosterone / metabolism
Sources: Crossref, ORCID
Added: August 28, 2020

2005 journal article

Resolving mechanisms of toxicity while pursuing ecotoxicological relevance?

Marine Pollution Bulletin, 51(8-12), 635–648.

By: D. Hinton*, S. Kullman*, R. Hardman*, D. Volz*, P. Chen*, M. Carney*, D. Bencic*

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Animals, Genetically Modified / metabolism; Carcinogenicity Tests / methods; Ecology / methods; Endocrine Disruptors / metabolism; Environmental Pollutants / metabolism; Models, Animal; Oligonucleotide Array Sequence Analysis / methods; Toxicology / methods; Toxicology / trends
Sources: Crossref, ORCID
Added: August 28, 2020

2004 journal article

Analysis of medaka cytochrome P450 3A homotropic and heterotropic cooperativity

Marine Environmental Research, 58(2-5), 469–473.

By: S. Kullman*, S. Kashiwada* & D. Hinton*

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Aryl Hydrocarbon Hydroxylases / metabolism; Catalysis; Coumarins / metabolism; Cytochrome P-450 CYP3A; Fluorescence; Kinetics; Models, Chemical; Oryzias / metabolism; Oxidoreductases, N-Demethylating / metabolism; Phenols / metabolism; Protein Binding; Substrate Specificity
Sources: Crossref, ORCID
Added: August 28, 2020

2004 chapter book

Bioinformatics Tools

By: K. Johnson, S. Kullman* & S. Lin

Sources: Crossref, ORCID
Added: September 13, 2022

2003 journal article

Analysis of medaka CYP3A gene regulation, promoter regulatory regions and cloning of the orphan nuclear receptor PXR

The MDIBL Bulletin, 42, 29–31.

By: S. Kullman & D. Hinton

Source: NC State University Libraries
Added: September 16, 2022

2003 journal article

Estrogen signaling in trout liver: Activation of the ras p21/MAP-kinase pathway

Environmental Science, 10, 223–227.

By: S. Kullman, F. Matsumura & D. Hinton

Source: NC State University Libraries
Added: September 16, 2022

2003 journal article

ras oncogene mutations in diethylnitrosamine-induced hepatic tumors in medaka (Oryzias latipes), a teleost fish

Mutation Research/Genetic Toxicology and Environmental Mutagenesis, 539(1-2), 43–53.

By: Z. Liu*, S. Kullman*, D. Bencic*, M. Torten* & D. Hinton*

co-author countries: United States of America 🇺🇸
author keywords: ras mutations; diethylnitrosamine; medaka; hepatic carcinogenesis
MeSH headings : Amino Acid Sequence; Animals; Base Sequence; DNA Mutational Analysis; Diethylnitrosamine; Genes, ras; Liver Neoplasms, Experimental / chemically induced; Liver Neoplasms, Experimental / genetics; Molecular Sequence Data; Mutation; Oryzias
Sources: Crossref, ORCID
Added: September 15, 2022

2002 journal article

Molecular cloning of rainbow trout (Oncorhynchus mykiss) eggshell zona radiata protein complementary DNA: mRNA expression in 17β-estradiol- and nonylphenol-treated fish

Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology, 132(2), 315–326.

By: A. Arukwe, S. Kullman*, K. Berg*, A. Goksøyr* & D. Hinton*

co-author countries: Norway 🇳🇴 United States of America 🇺🇸
author keywords: eggshell protein; cDNA cloning; liver; gene expression; xenoestrogen; biomarkers; environmental monitoring
MeSH headings : Amino Acid Sequence; Animals; Base Sequence; Cloning, Molecular; DNA Primers / genetics; DNA, Complementary / genetics; Egg Proteins / genetics; Egg Shell / chemistry; Estradiol / pharmacology; Gene Expression Profiling; Gene Expression Regulation / drug effects; Molecular Sequence Data; Oncorhynchus mykiss / genetics; Phenols / pharmacology; Phylogeny; Polymerase Chain Reaction; RNA, Messenger / genetics; RNA, Messenger / metabolism; Receptors, Estrogen / genetics; Vitellogenins / genetics
Sources: Crossref, ORCID
Added: September 15, 2022

2002 journal article

Toxicant induced differential gene expression and production of an aquatic gene array

The MDIBL Bulletin, 41, 58–61.

By: S. Kullman & D. Hinton

Source: NC State University Libraries
Added: September 16, 2022

2001 journal article

Differential biomarker gene and protein expressions in nonylphenol and estradiol-17β treated juvenile rainbow trout (Oncorhynchus mykiss)

Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology, 129(1), 1–10.

By: A. Arukwe*, S. Kullman & D. Hinton

co-author countries: Norway 🇳🇴
author keywords: estrogen-receptor; Zr-protein; vitellogenin; biomarkers; gene expression; xenoestrogen; rainbow trout
MeSH headings : Animals; Biomarkers; Blotting, Northern; Egg Proteins / genetics; Egg Proteins / metabolism; Enzyme-Linked Immunosorbent Assay; Estradiol / metabolism; Estradiol / pharmacology; Gene Expression Regulation / drug effects; Oncorhynchus mykiss / genetics; Oncorhynchus mykiss / metabolism; Phenols / metabolism; Phenols / pharmacology; Protein Biosynthesis; RNA, Messenger / metabolism; Receptors, Estrogen / genetics; Receptors, Estrogen / metabolism; Transcriptional Activation; Vitellogenins / genetics; Vitellogenins / metabolism
Sources: Crossref, ORCID
Added: September 15, 2022

2001 journal article

Identification, characterization, and ontogeny of a second cytochrome P450 3A gene from the fresh water teleost medaka (Oryzias latipes)

Molecular Reproduction and Development, 58(2), 149–158.

By: S. Kullman* & D. Hinton*

co-author countries: United States of America 🇺🇸
author keywords: CYP3A; embryo; development
Sources: Crossref, ORCID
Added: September 15, 2022

2000 journal article

Identification and Characterization of a cDNA Encoding Cytochrome P450 3A from the Fresh Water Teleost Medaka (Oryzias latipes)

Archives of Biochemistry and Biophysics, 380(1), 29–38.

By: S. Kullman*, J. Hamm* & D. Hinton*

co-author countries: United States of America 🇺🇸
author keywords: medaka; cytochrome P450; CYP3A; steroid metabolism
MeSH headings : Amino Acid Sequence; Animals; Aryl Hydrocarbon Hydroxylases; Base Sequence; Blotting, Northern; Blotting, Western; Cell Line; Cloning, Molecular; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System / biosynthesis; Cytochrome P-450 Enzyme System / genetics; DNA, Complementary / metabolism; Female; Fishes / genetics; Gene Library; Humans; Isoenzymes / biosynthesis; Isoenzymes / genetics; Liver / metabolism; Male; Microsomes, Liver / metabolism; Molecular Sequence Data; Oxidoreductases, N-Demethylating / biosynthesis; Oxidoreductases, N-Demethylating / genetics; RNA / metabolism; Recombinant Proteins / metabolism; Reverse Transcriptase Polymerase Chain Reaction; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Sex Factors; Testosterone / metabolism
Sources: Crossref, ORCID
Added: September 13, 2022

1997 journal article

Identification of a novel cytochrome P-450 gene from the white rot fungus Phanerochaete chrysosporium

Applied and Environmental Microbiology, 63(7), 2741–2746.

By: S. Kullman* & F. Matsumura*

co-author countries: United States of America 🇺🇸
MeSH headings : Amino Acid Sequence; Base Sequence; Basidiomycota / genetics; Blotting, Northern; Blotting, Western; Cloning, Molecular; Cytochrome P-450 Enzyme System / genetics; Gene Expression Regulation, Fungal; Heme / genetics; Heme / immunology; Molecular Sequence Data; Nitrogen / metabolism; Open Reading Frames; Polymerase Chain Reaction; RNA, Fungal / analysis; Sequence Homology, Amino Acid
Sources: Crossref, ORCID
Added: September 13, 2022

1996 journal article

Metabolic pathways utilized by Phanerochaete chrysosporium for degradation of the cyclodiene pesticide endosulfan

Applied and Environmental Microbiology, 62(2), 593–600.

By: S. Kullman* & F. Matsumura*

co-author countries: United States of America 🇺🇸
MeSH headings : Basidiomycota / metabolism; Biodegradation, Environmental; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System / metabolism; Endosulfan / chemistry; Endosulfan / metabolism; Gas Chromatography-Mass Spectrometry; Hydrocarbons, Chlorinated; Hydrolysis; Insecticides / chemistry; Insecticides / metabolism; Oxidation-Reduction; Peroxidases / metabolism; Piperonyl Butoxide / pharmacology
Sources: Crossref, ORCID
Added: September 13, 2022

1995 report

Bioremediation Principles: Laboratory Manual

Department of Civil and Environmental Engineering and US Department of Defense, Bioremediation course development for Marie Island Remediation.

By: S. Kullman, K. Lindenauer & M. Fuller

Source: NC State University Libraries
Added: September 16, 2022

1993 journal article

Development of antibodies against hydroxyatrazine and hydroxysimazine: Application to environmental samples

Journal of Agricultural and Food Chemistry, 41(9), 1523–1529.

By: A. Lucas, H. Bekheit, M. Goodrow, A. Jones, S. Kullman*, F. Matsumura, J. Woodrow, J. Seiber, B. Hammock

Sources: Crossref, ORCID
Added: September 15, 2022

Education

Updated: May 28th, 2014 11:01

University of California Davis Davis, CA, US
PhD Phamacology/Toxicology

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