Works (10)
Updated: July 5th, 2023 15:45
2021 journal article
Epistasis for head morphology in Drosophila melanogaster
G3-GENES GENOMES GENETICS, 11(10).
author keywords: Drosophila Genetic Reference Panel; genome-wide association analyses; modifier loci; genetic interaction network
MeSH headings : Alleles; Animals; Chromosome Mapping; Drosophila melanogaster / genetics; Epistasis, Genetic; Genome-Wide Association Study
TL;DR:
The Drosophila melanogaster Genetic Reference Panel of sequenced inbred lines is used to evaluate the magnitude of naturally occurring epistasis modifying the effects of mutations in jing and inv, two transcription factors that have subtle quantitative effects on head morphology as homozygotes.
(via Semantic Scholar)
open access via academic.oup.com (publisher PDF)
UN Sustainable Development Goal Categories
13. Climate Action
(Web of Science)
Source: Web Of Science
Added: January 10, 2022
2020 journal article
Gene expression networks in the Drosophila Genetic Reference Panel
GENOME RESEARCH, 30(3), 485–496.
MeSH headings : Animals; DNA Transposable Elements; Drosophila melanogaster / genetics; Drosophila melanogaster / metabolism; Drosophila melanogaster / microbiology; Female; Gene Expression Regulation; Gene Regulatory Networks; Genetic Variation; High-Throughput Nucleotide Sequencing; Male; Microbiota / genetics; Quantitative Trait Loci; Sequence Analysis, RNA
TL;DR:
This study performed deep RNA sequencing of 200 Drosophila Genetic Reference Panel inbred lines with complete genome sequences and mapped expression quantitative trait loci for annotated genes, novel transcribed regions, transposable elements and microbial species, providing new insights regarding the role of natural genetic variation in regulating gene expression.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: April 14, 2020
2019 journal article
Systems genetics of the Drosophila metabolome
GENOME RESEARCH, 30(3), 392–405.
MeSH headings : Animals; Drosophila melanogaster / genetics; Drosophila melanogaster / metabolism; Female; Genetic Association Studies; Genetic Variation; Male; Metabolome / genetics; Phenotype; Quantitative Trait Loci
TL;DR:
This work identified sex-specific modules of genetically correlated metabolites and constructed networks that integrate DNA sequence variation and variation in gene expression with variation in metabolites and organismal traits, including starvation stress resistance and male aggression.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: April 14, 2020
2012 journal article
Phenotypic Plasticity of the Drosophila Transcriptome
PLOS GENETICS, 8(3).
MeSH headings : Animals; Cluster Analysis; Drosophila melanogaster / genetics; Drosophila melanogaster / physiology; Gene Expression Regulation; Gene-Environment Interaction; Genetic Fitness; Genome, Insect; Phenotype; Transcriptome
TL;DR:
This analysis suggests that a restricted environmentally responsive segment of the transcriptome preserves the balance between phenotypic plasticity and environmental canalization.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
13. Climate Action
(Web of Science)
15. Life on Land
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
journal article
A drosophila model for toxicogenomics: Genetic variation in susceptibility to heavy metal exposure
Zhou, S. S., Luoma, S. E., Armour, G. E. S., Thakkar, E., Mackay, T. F. C., & Anholt, R. R. H. PLoS Genetics, 13(7).
Source: NC State University Libraries
Added: August 6, 2018
journal article
Genetic and genomic response to selection for food consumption in Drosophila melanogaster
Garlapow, M. E., Everett, L. J., Zhou, S. S., Gearhart, A. W., Fay, K. A., Huang, W., … Mackay, T. F. C. Behavior Genetics, 47(2), 227–243.
Source: NC State University Libraries
Added: August 6, 2018
journal article
Plasticity of the chemoreceptor repertoire in Drosophila melanogaster
Zhou, S. S., Stone, E. A., Mackay, T. F. C., & Anholt, R. R. H. PLoS Genetics, 5(10).
Source: NC State University Libraries
Added: August 6, 2018
journal article
The genetic basis for variation in sensitivity to lead toxicity in Drosophila melanogaster
Zhou, S. S., Morozova, T. V., Hussain, Y. N., Luoma, S. E., McCoy, L., Yamamoto, A., … Anholt, R. R. H. Environmental Health Perspectives, 124(7), 1062–1070.
Source: NC State University Libraries
Added: August 6, 2018
journal article
The genomic basis of postponed senescence in Drosophila melanogaster
Carnes, M. U., Campbell, T., Huang, W., Butler, D. G., Carbone, M. A., Duncan, L. H., … Mackay, T. F. C. PLoS One, 10(9).
Source: NC State University Libraries
Added: August 6, 2018
journal article
Tuning the chemosensory window A fly's perspective
Zhou, S. S., Mackay, T. F. C., & Anholt, R. R. H. Fly, 4(3), 230–235.
Source: NC State University Libraries
Added: August 6, 2018
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