Theresa Guillette

Works (6)

Updated: July 24th, 2023 08:21

2023 journal article

Domestic Dogs and Horses as Sentinels of Per- and Polyfluoroalkyl Substance Exposure and Associated Health Biomarkers in Gray's Creek North Carolina

ENVIRONMENTAL SCIENCE & TECHNOLOGY, 57(26), 9567–9579.

By: K. Rock n, M. Polera n, T. Guillette*, H. Starnes n, K. Dean, M. Watters, D. Stevens-Stewart, S. Belcher n 

author keywords: canine; drinking water; equine; fluoroether; One Health; nafion by-product 2; GenX chemicals; PFOA; PFOS
TL;DR: The utility of companion animal and livestock species as sentinels of PFAS exposure differences inside and outside of the home is supported, as in humans, renal and hepatic health in domestic animals may be sensitive to long-term PFAS exposures. (via Semantic Scholar)
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6. Clean Water and Sanitation (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: June 21, 2023

2022 journal article

Blood concentrations of per- and polyfluoroalkyl substances are associated with autoimmune-like effects in American alligators from Wilmington, North Carolina

FRONTIERS IN TOXICOLOGY, 4.

By: T. Guillette n, T. Jackson n, M. Guillette n, J. McCord* & S. Belcher n 

author keywords: autoantibodies; autoimmune; crocodilian; immune toxicity; lupus; one health; PFAS
TL;DR: The association of increased PFAS exposure with disrupted immune functions is interpreted to suggest that PFAS broadly alters immune activities resulting in autoimmune-like pathology in American alligators. (via Semantic Scholar)
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Sources: Web Of Science, ORCID, NC State University Libraries
Added: January 6, 2023

2020 journal article

A histological evaluation of pansteatitis-affected Mozambique tilapia,Oreochromis mossambicus(Peters 1852), from different geographical locations in South Africa

JOURNAL OF FISH DISEASES, 43(10), 1185–1199.

By: J. Sara*, W. Luus-Powell *, S. Fogelson, H. Botha *, T. Guillette n, W. Smit *, A. Hoffman*, K. Kunutu*, J. Koelmel *, J. Bowden *

author keywords: histopathology; Lake Flag Boshielo; Lake Loskop; Lake Luphephe-Nwanedi; Olifants River; pansteatitis
MeSH headings : Adipose Tissue / pathology; Air Sacs / pathology; Animals; Fish Diseases / pathology; Lakes; Liver / pathology; Rivers; South Africa; Steatitis / pathology; Tilapia
TL;DR: Investigation is warranted to understand the pervasiveness and mechanisms driving pathological changes of pansteatitis at Lake Flag Boshielo, Phalaborwa Barrage and Lake Luphephe-Nwanedi. (via Semantic Scholar)
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14. Life Below Water (OpenAlex)
Source: Web Of Science
Added: August 17, 2020

2020 journal article

Elevated levels of per- and polyfluoroalkyl substances in Cape Fear River Striped Bass (Morone saxatilis) are associated with biomarkers of altered immune and liver function

ENVIRONMENT INTERNATIONAL, 136.

By: T. Guillette n, J. McCord*, M. Guillette n, M. Polera n, K. Rachels*, C. Morgeson*, N. Kotlarz n , D. Knappe n  ...

Contributors: T. Guillette n, J. McCord*, M. Guillette n, M. Polera n, K. Rachels*, C. Morgeson*, N. Kotlarz n , D. Knappe  n ...

MeSH headings : Animals; Bass; Biomarkers; Fluorocarbons / toxicity; Liver; Rivers; Water Pollutants, Chemical / toxicity
TL;DR: The elevated PFAS concentrations found in the Cape Fear River Striped Bass were associated with biomarkers of alterations in the liver and immune system, and correlations betweenPFAS concentrations and health-related serum biomarkers were evaluated. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries, ORCID
Added: March 2, 2020

2019 journal article

Lipidomics for wildlife disease etiology and biomarker discovery: a case study of pansteatitis outbreak in South Africa

METABOLOMICS, 15(3).

By: J. Koelmel *, C. Ulmer *, S. Fogelson *, C. Jones *, H. Botha *, J. Bangma *, T. Guillette n, W. Luus-Powell * ...

author keywords: Pansteatitis; Lipidomics; Environmental metabolomics; Inflammation; Obesity; Oxidation
MeSH headings : Animals; Animals, Wild; Biomarkers; Chromatography, Liquid; Disease Outbreaks; Lipidomics / methods; Lipids / chemistry; South Africa / epidemiology; Tandem Mass Spectrometry; Tilapia / metabolism; Tilapia / parasitology
TL;DR: The application of lipidomics for in situ studies on Mozambique tilapia in Loskop Dam, South Africa is examined to understand the understanding of other environmentally-derived inflammatory conditions, such as those caused by obesogens. (via Semantic Scholar)
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Source: Web Of Science
Added: March 18, 2019

2018 journal article

Duality of estrogen receptor beta action in cancer progression

CURRENT OPINION IN PHARMACOLOGY, 41, 66–73.

By: T. Guillette n, T. Jackson n & S. Belcher n 

Contributors: T. Guillette n, T. Jackson n & S. Belcher n 

MeSH headings : Animals; Breast Neoplasms / metabolism; Breast Neoplasms / pathology; Cerebellar Neoplasms / metabolism; Cerebellar Neoplasms / pathology; Estrogen Receptor alpha / metabolism; Estrogen Receptor beta / metabolism; Female; Humans; Male; Medulloblastoma / metabolism; Medulloblastoma / pathology; Prostatic Neoplasms / metabolism; Prostatic Neoplasms / pathology
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3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: October 16, 2018

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