Tzu-Yu Chen

Works (7)

Updated: March 2nd, 2024 20:38

2023 article

Repurposing Iron- and 2-Oxoglutarate-Dependent Oxygenases to Catalyze Olefin Hydration

Wang, B., Lu, Y., Cha, L., Chen, T.-Y., Palacios, P. M., Li, L., … Chen, C. (2023, September 6). ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, Vol. 9.

By: B. Wang*, Y. Lu*, L. Cha n, T. Chen n, P. Palacios*, L. Li*, Y. Guo*, W. Chang n, C. Chen*

co-author countries: United States of America 🇺🇸
author keywords: Biocatalysis; Hydrogen Atom Transfer; Mukaiyama Hydration; Nonheme Fe/2OG-Dependent Oxygenase
Sources: Web Of Science, ORCID
Added: September 11, 2023

2022 journal article

Deciphering the Reaction Pathway of Mononuclear Iron Enzyme-Catalyzed N C Triple Bond Formation in Isocyanide Lipopeptide and Polyketide Biosynthesis

ACS CATALYSIS, 12(4), 2270–2279.

By: T. Chen n, Z. Zheng*, X. Zhang*, J. Chen*, L. Cha n, Y. Tang*, Y. Guo*, J. Zhou* ...

co-author countries: China 🇨🇳 United States of America 🇺🇸
author keywords: isocyanide; oxygenase; natural product; reaction mechanism; desaturation; C-N bond formation
Sources: Web Of Science, ORCID
Added: March 28, 2022

2022 journal article

Elucidation of divergent desaturation pathways in the formation of vinyl isonitrile and isocyanoacrylate

NATURE COMMUNICATIONS, 13(1).

By: W. Kim*, T. Chen n, L. Cha n, G. Zhou*, K. Xing*, N. Canty n, Y. Zhang*, W. Chang n

co-author countries: United States of America 🇺🇸
MeSH headings : Iron / metabolism; Ketoglutaric Acids / metabolism; Tyrosine
Sources: Web Of Science, ORCID
Added: September 26, 2022

2021 article

A postreplicative C5-cytosine hypermodification triggered by bacteriophage methyltransferase and hydroxylase

Chen, T.-Y., & Chang, W.-chen. (2021, July 13). PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Vol. 118.

By: T. Chen n & W. Chang n

co-author countries: United States of America 🇺🇸
MeSH headings : Bacteriophages / enzymology; Cytosine / metabolism; DNA Replication; Glycosylation; Glycosyltransferases / metabolism; Methyltransferases / metabolism; Mixed Function Oxygenases / metabolism; Substrate Specificity; Viral Proteins / metabolism
Sources: Web Of Science, ORCID
Added: August 23, 2021

2021 journal article

Current Understanding toward Isonitrile Group Biosynthesis and Mechanism

CHINESE JOURNAL OF CHEMISTRY, 39(2), 463–472.

co-author countries: China 🇨🇳 United States of America 🇺🇸
author keywords: Biosynthesis; Enzymes; Natural products; Reaction mechanisms; Biotransformations
Sources: Web Of Science, ORCID
Added: March 1, 2021

2021 journal article

Deciphering Pyrrolidine and Olefin Formation Mechanism in Kainic Acid Biosynthesis

ACS CATALYSIS, 11(1), 278–282.

By: T. Chen n, S. Xue*, W. Tsai*, T. Chien*, Y. Guo* & W. Chang n

co-author countries: Taiwan, Province of China 🇹🇼 United States of America 🇺🇸
author keywords: metalloenzyme; C-H activation; cyclization; desaturation; enzyme mechanism
Sources: Web Of Science, ORCID
Added: January 11, 2021

2020 journal article

Pathway from N-Alkylglycine to Alkylisonitrile Catalyzed by Iron(II) and 2-Oxoglutarate-Dependent Oxygenases

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 59(19), 7367–7371.

co-author countries: China 🇨🇳 United States of America 🇺🇸

Contributors: T. Chen n, J. Chen*, Y. Tang*, J. Zhou*, Y. Guo* & W. Chang n

author keywords: catalysis; decarboxylation; enzymes; iron; reaction mechanisms
MeSH headings : Catalysis; Glycine / analogs & derivatives; Glycine / chemical synthesis; Hydroxylation; Iron / chemistry; Models, Molecular; Nitriles / chemical synthesis; Nuclear Magnetic Resonance, Biomolecular; Oxidation-Reduction; Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase / chemistry; X-Ray Diffraction
Sources: Web Of Science, ORCID
Added: May 8, 2020

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