Works (35)

Updated: July 17th, 2023 21:14

2017 journal article

Thermodynamic and Kinetic Analyses of Iron Response Element (IRE)-mRNA Binding to Iron Regulatory Protein, IRP1

SCIENTIFIC REPORTS, 7.

By: M. Khan*, W. Walden*, E. Theil n & D. Goss*

co-author countries: Saudi Arabia 🇸🇦 United States of America 🇺🇸
MeSH headings : Aconitate Hydratase / genetics; Animals; Cations, Divalent / metabolism; Ferritins / genetics; Iron / metabolism; Iron Regulatory Protein 1 / metabolism; Kinetics; Manganese / metabolism; Protein Binding; RNA, Messenger / metabolism; Rabbits; Response Elements; Temperature
Source: Web Of Science
Added: August 6, 2018

2016 journal article

Modulating the permeability of ferritin channels

RSC ADVANCES, 6(25), 21219–21227.

co-author countries: Italy 🇮🇹 United States of America 🇺🇸
Source: Web Of Science
Added: August 6, 2018

2016 review

Solving Biology's Iron Chemistry Problem with Ferritin Protein Nanocages

[Review of ]. ACCOUNTS OF CHEMICAL RESEARCH, 49(5), 784–791.

By: E. Theil n, T. Tosha n & R. Beherat

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; DNA / metabolism; Ferric Compounds / chemistry; Ferritins / chemistry; Ferritins / genetics; Ferritins / metabolism; Heme / metabolism; Humans; Iron / chemistry; Iron / metabolism; Oxidoreductases / chemistry; Oxidoreductases / metabolism; Oxygen / chemistry; Oxygen / metabolism; Protein Structure, Quaternary; RNA, Messenger / metabolism
Source: Web Of Science
Added: August 6, 2018

2015 journal article

Fe2+ substrate transport through ferritin protein cage ion channels influences enzyme activity and biomineralization

JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY, 20(6), 957–969.

co-author countries: United Kingdom of Great Britain and Northern Ireland 🇬🇧 India 🇮🇳 Japan 🇯🇵 United States of America 🇺🇸
author keywords: Ferritin; Iron oxidation; Ion channels; Crystal structure; Electrostatics; Di-iron center; Diferric peroxo; Caged iron-oxy biomineral; Oxidoreductase enzyme reactivity
MeSH headings : Amino Acid Substitution; Crystallography, X-Ray; Ferritins / metabolism; Ferritins / ultrastructure; Ferrous Compounds / metabolism; Ion Channels / metabolism; Ion Channels / ultrastructure; Iron / chemistry; Kinetics; Protein Structure, Secondary
Source: Web Of Science
Added: August 6, 2018

2015 review

IRE mRNA riboregulators use metabolic iron (Fe2+) to control mRNA activity and iron chemistry in animals

[Review of ]. METALLOMICS, 7(1), 15–24.

By: E. Theil n

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Ferritins / chemistry; Ferritins / genetics; Ferritins / metabolism; Humans; Iron / chemistry; Iron / metabolism; Iron-Regulatory Proteins / chemistry; Iron-Regulatory Proteins / genetics; Iron-Regulatory Proteins / metabolism; RNA, Messenger / chemistry; RNA, Messenger / genetics; RNA, Messenger / metabolism
Source: Web Of Science
Added: August 6, 2018

2015 article

Is His54 a gating residue for the ferritin ferroxidase site?

Bernacchioni, C., Ciambellotti, S., Theil, E. C., & Turano, P. (2015, September). BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS, Vol. 1854, pp. 1118–1122.

By: C. Bernacchioni, S. Ciambellotti, E. Theil* & P. Turano

author keywords: Ferritin; Ferroxidase site; Reaction kinetics; Mutagenesis
MeSH headings : Binding Sites; Ceruloplasmin / chemistry; Crystallography, X-Ray; Ferritins / chemistry; Histidine / chemistry; Histidine / metabolism; Iron / chemistry
Source: Web Of Science
Added: August 6, 2018

2014 journal article

A role for iron and oxygen chemistry in preserving soft tissues, cells and molecules from deep time

By: M. Schweitzer, W. Zheng, T. Cleland, M. Goodwin, E. Boatman, E. Theil, M. Marcus, S. Fakra

Source: NC State University Libraries
Added: August 6, 2018

2014 journal article

Coordinating subdomains of ferritin protein cages with catalysis and biomineralization viewed from the C (4) cage axes

JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY, 19(4-5), 615–622.

By: E. Theil n, P. Turano*, V. Ghini*, M. Allegrozzi* & C. Bernacchioni*

co-author countries: Italy 🇮🇹 United States of America 🇺🇸
author keywords: Ferritin; Protein nanocage; Ferric oxo; Di-iron protein; Nanobiomineral
MeSH headings : Catalysis; Ferric Compounds / chemistry; Ferric Compounds / metabolism; Ferritins / chemistry; Ferritins / metabolism; Iron / chemistry; Iron / metabolism; Protein Structure, Secondary
Source: Web Of Science
Added: August 6, 2018

2014 journal article

Loop Electrostatics Modulates the Intersubunit Interactions in Ferritin

ACS CHEMICAL BIOLOGY, 9(11), 2517–2525.

co-author countries: Italy 🇮🇹 United States of America 🇺🇸
MeSH headings : Circular Dichroism; Electrophoresis, Polyacrylamide Gel; Ferritins / chemistry; Ferritins / genetics; Microscopy, Electron, Transmission; Mutagenesis, Site-Directed; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Static Electricity
Source: Web Of Science
Added: August 6, 2018

2014 journal article

Moving Fe2+ from ferritin ion channels to catalytic OH centers depends on conserved protein cage carboxylates

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 111(22), 7925–7930.

By: R. Behera & E. Theil n

co-author countries: United States of America 🇺🇸
author keywords: iron traffic; oxidoreductase enzyme activity; antioxidant; ferrihydrite; BioIron
MeSH headings : Animals; Antioxidants / chemistry; Antioxidants / metabolism; Anura; Catalysis; Conserved Sequence; Ferric Compounds / chemistry; Ferric Compounds / metabolism; Ferritins / chemistry; Ferritins / genetics; Ferritins / metabolism; Heme / chemistry; Heme / metabolism; Hydroxides / chemistry; Hydroxides / metabolism; Ion Channels / chemistry; Ion Channels / metabolism; Iron / chemistry; Iron / metabolism; Metals / chemistry; Metals / metabolism; Minerals / chemistry; Minerals / metabolism; Models, Chemical; Mutagenesis, Site-Directed; Oxidoreductases / chemistry; Oxidoreductases / metabolism; Protein Structure, Secondary; Protein Structure, Tertiary; Substrate Specificity; Sulfates / chemistry; Sulfates / metabolism
Source: Web Of Science
Added: August 6, 2018

2014 journal article

Rapid kinetics of iron responsive element (IRE) RNA/iron regulatory protein 1 and IRE-RNA/eIF4F complexes respond differently to metal ions

NUCLEIC ACIDS RESEARCH, 42(10), 6567–6577.

By: M. Khan*, J. Ma*, W. Walden*, W. Merrick*, E. Theil* & D. Goss*

co-author countries: United States of America 🇺🇸
MeSH headings : Aconitate Hydratase / genetics; Aconitate Hydratase / metabolism; Animals; Eukaryotic Initiation Factor-4F / metabolism; Ferritins / genetics; Ferritins / metabolism; Iron / metabolism; Iron Regulatory Protein 1 / chemistry; Iron Regulatory Protein 1 / metabolism; Kinetics; Manganese / chemistry; Potassium / chemistry; RNA, Messenger / chemistry; RNA, Messenger / metabolism; Rabbits; Regulatory Sequences, Ribonucleic Acid
Source: Web Of Science
Added: August 6, 2018

2014 journal article

Spectroscopic Studies of Single and Double Variants of M Ferritin: Lack of Conversion of a Biferrous Substrate Site into a Cofactor Site for O-2 Activation

BIOCHEMISTRY, 53(3), 473–482.

By: Y. Kwak*, J. Schwartz*, S. Haldar, R. Behera, T. Tosha, E. Theil n, E. Solomon*

co-author countries: United States of America 🇺🇸
MeSH headings : Amino Acid Sequence; Animals; Catalytic Domain; Circular Dichroism; Ferritins / chemistry; Ferritins / genetics; Ferrous Compounds / chemistry; Histidine / chemistry; Iron / chemistry; Ligands; Models, Molecular; Mutation; Oxygen / chemistry; Oxygen / metabolism; Rana catesbeiana; Ribonucleotide Reductases / chemistry
Source: Web Of Science
Added: August 6, 2018

2013 journal article

Ferritin: The Protein Nanocage and Iron Biomineral in Health and in Disease

INORGANIC CHEMISTRY, 52(21), 12223–12233.

By: E. Theil n

co-author countries: United States of America 🇺🇸
MeSH headings : Anemia / drug therapy; Animals; Catalytic Domain; Drug Delivery Systems / methods; Ferritins / chemistry; Ferritins / genetics; Ferritins / metabolism; Hemosiderin / metabolism; Humans; Iron Overload / drug therapy; Molecular Targeted Therapy / methods; Nanostructures / administration & dosage; RNA, Messenger; Transfusion Reaction
Source: Web Of Science
Added: August 6, 2018

2013 journal article

METALLOENZYMES Cage redesign explains assembly

Nature Chemical Biology, 9(3), 143–144.

By: E. Theil & P. Turano

Source: NC State University Libraries
Added: August 6, 2018

2011 article

New Dimensions of RNA in Molecular Recognition and Catalysis

Theil, E. C., & Westhof, E. (2011, December). ACCOUNTS OF CHEMICAL RESEARCH, Vol. 44, pp. 1255–1256.

By: E. Theil* & E. Westhof*

co-author countries: France 🇫🇷
MeSH headings : Catalysis; RNA / chemistry; RNA / metabolism; RNA, Catalytic / chemistry; RNA, Catalytic / metabolism; RNA, Untranslated / chemistry; RNA, Untranslated / metabolism
Source: Web Of Science
Added: August 6, 2018

2000 journal article

Identification and characterization of the iron regulatory element in the ferritin gene of a plant (soybean)

JOURNAL OF BIOLOGICAL CHEMISTRY, 275(23), 17488–17493.

By: J. Wei n & E. Theil n

co-author countries: United States of America 🇺🇸
MeSH headings : Base Sequence; Ferritins / genetics; Genes, Reporter; Glucuronidase / genetics; Iron / metabolism; Iron-Regulatory Proteins; Iron-Sulfur Proteins / metabolism; Luciferases / genetics; Molecular Sequence Data; Mutagenesis, Insertional; Plant Leaves; Promoter Regions, Genetic; RNA, Messenger / genetics; RNA-Binding Proteins / metabolism; Recombinant Proteins / biosynthesis; Sequence Deletion; Soybeans / genetics
Source: Web Of Science
Added: August 6, 2018

2000 journal article

Internal loop/bulge and hairpin loop of the iron-responsive element of ferritin mRNA contribute to maximal iron regulatory protein 2 binding and translational regulation in the iso-iron-responsive element/iso-iron regulatory protein family

BIOCHEMISTRY, 39(20), 6235–6242.

By: Y. Ke n, H. Sierzputowska-Gracz n, Z. Gdaniec n & E. Theil n

co-author countries: Poland 🇵🇱 United States of America 🇺🇸
MeSH headings : Animals; Copper / chemistry; Ferritins / antagonists & inhibitors; Ferritins / biosynthesis; Ferritins / chemistry; Ferritins / genetics; Hot Temperature; Iron Regulatory Protein 1; Iron Regulatory Protein 2; Iron-Regulatory Proteins; Iron-Sulfur Proteins / chemistry; Iron-Sulfur Proteins / genetics; Iron-Sulfur Proteins / physiology; Lizards; Magnesium / chemistry; Multigene Family; Mutagenesis, Site-Directed; Nuclear Magnetic Resonance, Biomolecular; Nucleic Acid Conformation; Phenanthrolines / chemistry; Protein Binding / genetics; Protein Biosynthesis; Protein Denaturation; Protein Isoforms / chemistry; Protein Isoforms / genetics; RNA, Messenger / chemistry; RNA-Binding Proteins / chemistry; RNA-Binding Proteins / genetics; RNA-Binding Proteins / physiology; Rabbits; Rana catesbeiana; Repressor Proteins / genetics; Repressor Proteins / physiology; Ribonuclease T1 / chemistry
Source: Web Of Science
Added: August 6, 2018

2000 journal article

The ferritin iron entry and exit problem

INORGANICA CHIMICA ACTA, 297(1-2), 242–251.

By: E. Theil*, H. Takagi n, G. Small n, L. He n, A. Tipton & D. Danger n

co-author countries: United States of America 🇺🇸
author keywords: ferritin; iron biominerals; ferroxidation; iron/dioxygen catalysis
Source: Web Of Science
Added: August 6, 2018

1999 journal article

Crystal structure of bullfrog M ferritin at 2.8 angstrom resolution: analysis of subunit interactions and the binuclear metal center

JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY, 4(3), 243–256.

By: Y. Ha*, D. Shi*, G. Small n, E. Theil n & N. Allewell*

co-author countries: United States of America 🇺🇸
author keywords: crystallography; iron oxidation; iron storage; multisubunit proteins
MeSH headings : Amino Acid Sequence; Animals; Aspartic Acid; Binding Sites; Conserved Sequence; Crystallography, X-Ray; Ferritins / chemistry; Ferritins / metabolism; Magnesium / metabolism; Models, Molecular; Molecular Sequence Data; Protein Conformation; Rana catesbeiana; Sequence Homology, Amino Acid; Tyrosine / analysis; Tyrosine / metabolism
Source: Web Of Science
Added: August 6, 2018

1999 article

Iron regulatory element and internal loop/bulge structure for ferritin mRNA studied by cobalt(III) hexammine binding, molecular modeling, and NMR spectroscopy (vol 37, pg 1505, 1998)

Gdaniec, Z., Sierzputowska-Gracz, H., & Theil, E. C. (1999, April 27). BIOCHEMISTRY, Vol. 38, pp. 5676–5676.

By: Z. Gdaniec, H. Sierzputowska-Gracz* & E. Theil*

Source: Web Of Science
Added: August 6, 2018

1998 journal article

Direct spectroscopic and kinetic evidence for the involvement of a peroxodiferric intermediate during the ferroxidase reaction in fast ferritin mineralization

BIOCHEMISTRY, 37(28), 9871–9876.

By: A. Pereira n, W. Small n, C. Krebs n, P. Tavares n, D. Edmondson n, E. Theil n, B. Huynh n

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Anura; Ceruloplasmin / chemistry; Ferric Compounds / chemistry; Ferritins / chemistry; Ferritins / genetics; Humans; Kinetics; Oxidation-Reduction; Recombinant Proteins / chemistry; Spectroscopy, Mossbauer
Source: Web Of Science
Added: August 6, 2018

1998 journal article

Evidence for reutilization of nodule iron in soybean seed development

JOURNAL OF PLANT NUTRITION, 21(5), 913–927.

By: J. Burton n, C. Harlow n & E. Theil n

co-author countries: United States of America 🇺🇸
Source: Web Of Science
Added: August 6, 2018

1998 journal article

Iron regulatory element and internal loop/bulge structure for ferritin mRNA studied by cobalt(III) hexammine binding, molecular modeling, and NMR spectroscopy

BIOCHEMISTRY, 37(6), 1505–1512.

By: Z. Gdaniec n, H. Sierzputowska-Gracz n & E. Theil n

co-author countries: Poland 🇵🇱 United States of America 🇺🇸
MeSH headings : Animals; Anura; Binding Sites / drug effects; Binding Sites / genetics; Chlorides / metabolism; Chlorides / pharmacology; Cobalt / metabolism; Cobalt / pharmacology; Ferritins / genetics; Indicators and Reagents; Iron-Regulatory Proteins; Iron-Sulfur Proteins / chemistry; Iron-Sulfur Proteins / drug effects; Iron-Sulfur Proteins / genetics; Iron-Sulfur Proteins / metabolism; Magnetic Resonance Spectroscopy; Models, Molecular; Nucleic Acid Conformation; Protons; RNA, Messenger / chemistry; RNA, Messenger / metabolism; RNA-Binding Proteins / chemistry; RNA-Binding Proteins / drug effects; RNA-Binding Proteins / genetics; RNA-Binding Proteins / metabolism
Source: Web Of Science
Added: August 6, 2018

1998 journal article

Localized unfolding at the junction of three ferritin subunits - A mechanism for iron release?

JOURNAL OF BIOLOGICAL CHEMISTRY, 273(30), 18685–18688.

By: H. Takagi, D. Shi, Y. Ha, N. Allewell & E. Theil*

MeSH headings : Amino Acid Substitution; Animals; Crystallography, X-Ray; Ferritins / genetics; Ferritins / metabolism; Iron / metabolism; Kinetics; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Folding; Ranidae; Spectrophotometry, Atomic; Structure-Activity Relationship
Source: Web Of Science
Added: August 6, 2018

1998 journal article

Loops and bulge/loops in iron-responsive element isoforms influence iron regulatory protein binding - Fine-tuning of mRNA regulation?

JOURNAL OF BIOLOGICAL CHEMISTRY, 273(37), 23637–23640.

By: Y. Ke, J. Wu, E. Leibold, W. Walden & E. Theil*

MeSH headings : 5-Aminolevulinate Synthetase / genetics; Aconitate Hydratase / genetics; Animals; Base Composition; Base Sequence; Cloning, Molecular; Ferritins / genetics; Gene Expression Regulation; Iron Regulatory Protein 1; Iron Regulatory Protein 2; Iron-Regulatory Proteins; Iron-Sulfur Proteins / genetics; Iron-Sulfur Proteins / metabolism; Liver / metabolism; Nucleic Acid Conformation; RNA, Messenger / biosynthesis; RNA, Messenger / chemistry; RNA, Messenger / genetics; RNA-Binding Proteins / genetics; RNA-Binding Proteins / metabolism; Rabbits; Receptors, Transferrin / genetics; Recombinant Proteins / metabolism; Saccharomyces cerevisiae
Source: Web Of Science
Added: August 6, 2018

1998 patent

Methods of identifying transition metal complexes that selectively cleave regulatory elements of mRNA and uses thereof

Washington, DC: U.S. Patent and Trademark Office.

By: E. Theil

Source: NC State University Libraries
Added: August 6, 2018

1998 book

Principles of chemistry in biology: A teaching companion

Washington, DC: American Chemical Society; Distributed by Oxford University Press.

Source: NC State University Libraries
Added: August 6, 2018

1998 journal article

The iron responsive element (IRE) family of mRNA regulators: Regulation of iron transport and uptake compared in animals, plants, and microorganisms

Iron Transport and Storage in Microorganisms, Plants and Animals, 35(1998), 403–434.

By: E. Theil

Source: NC State University Libraries
Added: August 6, 2018

1997 journal article

Preliminary analysis of amphibian red cell M ferritin in a novel tetragonal unit cell

ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY, 53, 513–523.

By: Y. Ha*, E. Theil* & N. Allewell*

co-author countries: United States of America 🇺🇸
Source: Web Of Science
Added: August 6, 2018

1997 journal article

Rapid and parallel formation of Fe3+ multimers, including a trimer, during H-type subunit ferritin mineralization

BIOCHEMISTRY, 36(25), 7917–7927.

By: A. Pereira n, P. Tavares n, S. Lloyd n, D. Danger n, D. Edmondson n, E. Theil n, B. Huynh n

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Anura; Biopolymers; Electron Spin Resonance Spectroscopy; Ferric Compounds / chemistry; Ferritins / chemistry; Minerals / chemistry; Oxidation-Reduction; Recombinant Proteins / chemistry; Spectroscopy, Mossbauer
Source: Web Of Science
Added: August 6, 2018

1997 journal article

Sustainable solution for dietary iron deficiency through plant biotechnology and breeding to increase seed ferritin control

European Journal of Clinical Nutrition, 51(Suppl. 4), S28–31.

By: E. Theil, J. Burton & J. Beard

Source: NC State University Libraries
Added: August 6, 2018

1997 journal article

The influence of conserved tyrosine 30 and tissue-dependent differences in sequence on ferritin function: use of blue and purple Fe(III) species as reporters of ferroxidation

Journal of Biological Inorganic Chemistry, 2(5), 652–661.

By: J. Fetter n, J. Cohen*, D. Danger n, L. Sanders* & E. Theil n

co-author countries: United States of America 🇺🇸
Source: NC State University Libraries
Added: August 6, 2018

1997 chapter

Translational regulation of bioiron

In S. Silver & W. Walden (Eds.), Metal ions in gene regulation (pp. 131–156).

By: E. Theil*

Ed(s): . S. Silver & W. Walden

Source: NC State University Libraries
Added: August 6, 2018

1990 journal article

Regulation of ferritin and transferrin receptor messenger-rnas

Journal of Biological Chemistry, 265(9), 4771–4774.

By: E. Theil

Source: NC State University Libraries
Added: August 6, 2018

1987 review

FERRITIN - STRUCTURE, GENE-REGULATION, AND CELLULAR FUNCTION IN ANIMALS, PLANTS, AND MICROORGANISMS

[Review of ]. ANNUAL REVIEW OF BIOCHEMISTRY, 56, 289–315.

By: E. Theil*

Source: Web Of Science
Added: August 6, 2018