Works (35)

Updated: July 17th, 2023 21:14

2017 journal article

Thermodynamic and Kinetic Analyses of Iron Response Element (IRE)-mRNA Binding to Iron Regulatory Protein, IRP1

SCIENTIFIC REPORTS, 7.

By: M. Khan*, W. Walden*, E. Theil n & D. Gossโ€‰*

co-author countries: Saudi Arabia ๐Ÿ‡ธ๐Ÿ‡ฆ United States of America ๐Ÿ‡บ๐Ÿ‡ธ
MeSH headings : Aconitate Hydratase / genetics; Animals; Cations, Divalent / metabolism; Ferritins / genetics; Iron / metabolism; Iron Regulatory Protein 1 / metabolism; Kinetics; Manganese / metabolism; Protein Binding; RNA, Messenger / metabolism; Rabbits; Response Elements; Temperature
Source: Web Of Science
Added: August 6, 2018

2016 journal article

Modulating the permeability of ferritin channels

RSC ADVANCES, 6(25), 21219โ€“21227.

co-author countries: Italy ๐Ÿ‡ฎ๐Ÿ‡น United States of America ๐Ÿ‡บ๐Ÿ‡ธ
Source: Web Of Science
Added: August 6, 2018

2016 review

Solving Biology's Iron Chemistry Problem with Ferritin Protein Nanocages

[Review of ]. ACCOUNTS OF CHEMICAL RESEARCH, 49(5), 784โ€“791.

By: E. Theil n, T. Toshaโ€‰ n & R. Beherat

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
MeSH headings : Animals; DNA / metabolism; Ferric Compounds / chemistry; Ferritins / chemistry; Ferritins / genetics; Ferritins / metabolism; Heme / metabolism; Humans; Iron / chemistry; Iron / metabolism; Oxidoreductases / chemistry; Oxidoreductases / metabolism; Oxygen / chemistry; Oxygen / metabolism; Protein Structure, Quaternary; RNA, Messenger / metabolism
Source: Web Of Science
Added: August 6, 2018

2015 journal article

Fe2+ substrate transport through ferritin protein cage ion channels influences enzyme activity and biomineralization

JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY, 20(6), 957โ€“969.

co-author countries: United Kingdom of Great Britain and Northern Ireland ๐Ÿ‡ฌ๐Ÿ‡ง India ๐Ÿ‡ฎ๐Ÿ‡ณ Japan ๐Ÿ‡ฏ๐Ÿ‡ต United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: Ferritin; Iron oxidation; Ion channels; Crystal structure; Electrostatics; Di-iron center; Diferric peroxo; Caged iron-oxy biomineral; Oxidoreductase enzyme reactivity
MeSH headings : Amino Acid Substitution; Crystallography, X-Ray; Ferritins / metabolism; Ferritins / ultrastructure; Ferrous Compounds / metabolism; Ion Channels / metabolism; Ion Channels / ultrastructure; Iron / chemistry; Kinetics; Protein Structure, Secondary
Source: Web Of Science
Added: August 6, 2018

2015 review

IRE mRNA riboregulators use metabolic iron (Fe2+) to control mRNA activity and iron chemistry in animals

[Review of ]. METALLOMICS, 7(1), 15โ€“24.

By: E. Theil n

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
MeSH headings : Animals; Ferritins / chemistry; Ferritins / genetics; Ferritins / metabolism; Humans; Iron / chemistry; Iron / metabolism; Iron-Regulatory Proteins / chemistry; Iron-Regulatory Proteins / genetics; Iron-Regulatory Proteins / metabolism; RNA, Messenger / chemistry; RNA, Messenger / genetics; RNA, Messenger / metabolism
Source: Web Of Science
Added: August 6, 2018

2015 article

Is His54 a gating residue for the ferritin ferroxidase site?

Bernacchioni, C., Ciambellotti, S., Theil, E. C., & Turano, P. (2015, September). BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS, Vol. 1854, pp. 1118โ€“1122.

By: C. Bernacchioni, S. Ciambellotti, E. Theil* & P. Turano

author keywords: Ferritin; Ferroxidase site; Reaction kinetics; Mutagenesis
MeSH headings : Binding Sites; Ceruloplasmin / chemistry; Crystallography, X-Ray; Ferritins / chemistry; Histidine / chemistry; Histidine / metabolism; Iron / chemistry
Source: Web Of Science
Added: August 6, 2018

2014 journal article

A role for iron and oxygen chemistry in preserving soft tissues, cells and molecules from deep time

By: M. Schweitzerโ€‰, W. Zheng, T. Cleland, M. Goodwin, E. Boatman, E. Theil, M. Marcus, S. Fakra

Source: NC State University Libraries
Added: August 6, 2018

2014 journal article

Coordinating subdomains of ferritin protein cages with catalysis and biomineralization viewed from the C (4) cage axes

JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY, 19(4-5), 615โ€“622.

By: E. Theil n, P. Turanoโ€‰*, V. Ghiniโ€‰*, M. Allegrozzi* & C. Bernacchioniโ€‰*

co-author countries: Italy ๐Ÿ‡ฎ๐Ÿ‡น United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: Ferritin; Protein nanocage; Ferric oxo; Di-iron protein; Nanobiomineral
MeSH headings : Catalysis; Ferric Compounds / chemistry; Ferric Compounds / metabolism; Ferritins / chemistry; Ferritins / metabolism; Iron / chemistry; Iron / metabolism; Protein Structure, Secondary
Source: Web Of Science
Added: August 6, 2018

2014 journal article

Loop Electrostatics Modulates the Intersubunit Interactions in Ferritin

ACS CHEMICAL BIOLOGY, 9(11), 2517โ€“2525.

co-author countries: Italy ๐Ÿ‡ฎ๐Ÿ‡น United States of America ๐Ÿ‡บ๐Ÿ‡ธ
MeSH headings : Circular Dichroism; Electrophoresis, Polyacrylamide Gel; Ferritins / chemistry; Ferritins / genetics; Microscopy, Electron, Transmission; Mutagenesis, Site-Directed; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Static Electricity
Source: Web Of Science
Added: August 6, 2018

2014 journal article

Moving Fe2+ from ferritin ion channels to catalytic OH centers depends on conserved protein cage carboxylates

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 111(22), 7925โ€“7930.

By: R. Behera & E. Theil n

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: iron traffic; oxidoreductase enzyme activity; antioxidant; ferrihydrite; BioIron
MeSH headings : Animals; Antioxidants / chemistry; Antioxidants / metabolism; Anura; Catalysis; Conserved Sequence; Ferric Compounds / chemistry; Ferric Compounds / metabolism; Ferritins / chemistry; Ferritins / genetics; Ferritins / metabolism; Heme / chemistry; Heme / metabolism; Hydroxides / chemistry; Hydroxides / metabolism; Ion Channels / chemistry; Ion Channels / metabolism; Iron / chemistry; Iron / metabolism; Metals / chemistry; Metals / metabolism; Minerals / chemistry; Minerals / metabolism; Models, Chemical; Mutagenesis, Site-Directed; Oxidoreductases / chemistry; Oxidoreductases / metabolism; Protein Structure, Secondary; Protein Structure, Tertiary; Substrate Specificity; Sulfates / chemistry; Sulfates / metabolism
Source: Web Of Science
Added: August 6, 2018

2014 journal article

Rapid kinetics of iron responsive element (IRE) RNA/iron regulatory protein 1 and IRE-RNA/eIF4F complexes respond differently to metal ions

NUCLEIC ACIDS RESEARCH, 42(10), 6567โ€“6577.

By: M. Khan*, J. Maโ€‰*, W. Walden*, W. Merrick*, E. Theil* & D. Gossโ€‰*

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
MeSH headings : Aconitate Hydratase / genetics; Aconitate Hydratase / metabolism; Animals; Eukaryotic Initiation Factor-4F / metabolism; Ferritins / genetics; Ferritins / metabolism; Iron / metabolism; Iron Regulatory Protein 1 / chemistry; Iron Regulatory Protein 1 / metabolism; Kinetics; Manganese / chemistry; Potassium / chemistry; RNA, Messenger / chemistry; RNA, Messenger / metabolism; Rabbits; Regulatory Sequences, Ribonucleic Acid
Source: Web Of Science
Added: August 6, 2018

2014 journal article

Spectroscopic Studies of Single and Double Variants of M Ferritin: Lack of Conversion of a Biferrous Substrate Site into a Cofactor Site for O-2 Activation

BIOCHEMISTRY, 53(3), 473โ€“482.

By: Y. Kwak*, J. Schwartz*, S. Haldar, R. Behera, T. Tosha, E. Theil n, E. Solomonโ€‰*

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
MeSH headings : Amino Acid Sequence; Animals; Catalytic Domain; Circular Dichroism; Ferritins / chemistry; Ferritins / genetics; Ferrous Compounds / chemistry; Histidine / chemistry; Iron / chemistry; Ligands; Models, Molecular; Mutation; Oxygen / chemistry; Oxygen / metabolism; Rana catesbeiana; Ribonucleotide Reductases / chemistry
Source: Web Of Science
Added: August 6, 2018

2013 journal article

Ferritin: The Protein Nanocage and Iron Biomineral in Health and in Disease

INORGANIC CHEMISTRY, 52(21), 12223โ€“12233.

By: E. Theil n

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
MeSH headings : Anemia / drug therapy; Animals; Catalytic Domain; Drug Delivery Systems / methods; Ferritins / chemistry; Ferritins / genetics; Ferritins / metabolism; Hemosiderin / metabolism; Humans; Iron Overload / drug therapy; Molecular Targeted Therapy / methods; Nanostructures / administration & dosage; RNA, Messenger; Transfusion Reaction
Source: Web Of Science
Added: August 6, 2018

2013 journal article

METALLOENZYMES Cage redesign explains assembly

Nature Chemical Biology, 9(3), 143โ€“144.

By: E. Theil & P. Turano

Source: NC State University Libraries
Added: August 6, 2018

2011 article

New Dimensions of RNA in Molecular Recognition and Catalysis

Theil, E. C., & Westhof, E. (2011, December). ACCOUNTS OF CHEMICAL RESEARCH, Vol. 44, pp. 1255โ€“1256.

By: E. Theil* & E. Westhofโ€‰*

co-author countries: France ๐Ÿ‡ซ๐Ÿ‡ท
MeSH headings : Catalysis; RNA / chemistry; RNA / metabolism; RNA, Catalytic / chemistry; RNA, Catalytic / metabolism; RNA, Untranslated / chemistry; RNA, Untranslated / metabolism
Source: Web Of Science
Added: August 6, 2018

2000 journal article

Identification and characterization of the iron regulatory element in the ferritin gene of a plant (soybean)

JOURNAL OF BIOLOGICAL CHEMISTRY, 275(23), 17488โ€“17493.

By: J. Wei n & E. Theil n

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
MeSH headings : Base Sequence; Ferritins / genetics; Genes, Reporter; Glucuronidase / genetics; Iron / metabolism; Iron-Regulatory Proteins; Iron-Sulfur Proteins / metabolism; Luciferases / genetics; Molecular Sequence Data; Mutagenesis, Insertional; Plant Leaves; Promoter Regions, Genetic; RNA, Messenger / genetics; RNA-Binding Proteins / metabolism; Recombinant Proteins / biosynthesis; Sequence Deletion; Soybeans / genetics
Source: Web Of Science
Added: August 6, 2018

2000 journal article

Internal loop/bulge and hairpin loop of the iron-responsive element of ferritin mRNA contribute to maximal iron regulatory protein 2 binding and translational regulation in the iso-iron-responsive element/iso-iron regulatory protein family

BIOCHEMISTRY, 39(20), 6235โ€“6242.

By: Y. Ke n, H. Sierzputowska-Gracz n, Z. Gdaniecโ€‰ n & E. Theil n

co-author countries: Poland ๐Ÿ‡ต๐Ÿ‡ฑ United States of America ๐Ÿ‡บ๐Ÿ‡ธ
MeSH headings : Animals; Copper / chemistry; Ferritins / antagonists & inhibitors; Ferritins / biosynthesis; Ferritins / chemistry; Ferritins / genetics; Hot Temperature; Iron Regulatory Protein 1; Iron Regulatory Protein 2; Iron-Regulatory Proteins; Iron-Sulfur Proteins / chemistry; Iron-Sulfur Proteins / genetics; Iron-Sulfur Proteins / physiology; Lizards; Magnesium / chemistry; Multigene Family; Mutagenesis, Site-Directed; Nuclear Magnetic Resonance, Biomolecular; Nucleic Acid Conformation; Phenanthrolines / chemistry; Protein Binding / genetics; Protein Biosynthesis; Protein Denaturation; Protein Isoforms / chemistry; Protein Isoforms / genetics; RNA, Messenger / chemistry; RNA-Binding Proteins / chemistry; RNA-Binding Proteins / genetics; RNA-Binding Proteins / physiology; Rabbits; Rana catesbeiana; Repressor Proteins / genetics; Repressor Proteins / physiology; Ribonuclease T1 / chemistry
Source: Web Of Science
Added: August 6, 2018

2000 journal article

The ferritin iron entry and exit problem

INORGANICA CHIMICA ACTA, 297(1-2), 242โ€“251.

By: E. Theil*, H. Takagi n, G. Small n, L. He n, A. Tipton & D. Danger n

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: ferritin; iron biominerals; ferroxidation; iron/dioxygen catalysis
Source: Web Of Science
Added: August 6, 2018

1999 journal article

Crystal structure of bullfrog M ferritin at 2.8 angstrom resolution: analysis of subunit interactions and the binuclear metal center

JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY, 4(3), 243โ€“256.

By: Y. Ha*, D. Shi*, G. Small n, E. Theil n & N. Allewellโ€‰*

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: crystallography; iron oxidation; iron storage; multisubunit proteins
MeSH headings : Amino Acid Sequence; Animals; Aspartic Acid; Binding Sites; Conserved Sequence; Crystallography, X-Ray; Ferritins / chemistry; Ferritins / metabolism; Magnesium / metabolism; Models, Molecular; Molecular Sequence Data; Protein Conformation; Rana catesbeiana; Sequence Homology, Amino Acid; Tyrosine / analysis; Tyrosine / metabolism
Source: Web Of Science
Added: August 6, 2018

1999 article

Iron regulatory element and internal loop/bulge structure for ferritin mRNA studied by cobalt(III) hexammine binding, molecular modeling, and NMR spectroscopy (vol 37, pg 1505, 1998)

Gdaniec, Z., Sierzputowska-Gracz, H., & Theil, E. C. (1999, April 27). BIOCHEMISTRY, Vol. 38, pp. 5676โ€“5676.

By: Z. Gdaniec, H. Sierzputowska-Gracz* & E. Theil*

Source: Web Of Science
Added: August 6, 2018

1998 journal article

Direct spectroscopic and kinetic evidence for the involvement of a peroxodiferric intermediate during the ferroxidase reaction in fast ferritin mineralization

BIOCHEMISTRY, 37(28), 9871โ€“9876.

By: A. Pereiraโ€‰ n, W. Smallโ€‰ n, C. Krebsโ€‰ n, P. Tavaresโ€‰ n, D. Edmondson n, E. Theil n, B. Huynh n

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
MeSH headings : Animals; Anura; Ceruloplasmin / chemistry; Ferric Compounds / chemistry; Ferritins / chemistry; Ferritins / genetics; Humans; Kinetics; Oxidation-Reduction; Recombinant Proteins / chemistry; Spectroscopy, Mossbauer
Source: Web Of Science
Added: August 6, 2018

1998 journal article

Evidence for reutilization of nodule iron in soybean seed development

JOURNAL OF PLANT NUTRITION, 21(5), 913โ€“927.

By: J. Burton n, C. Harlow n & E. Theil n

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
Source: Web Of Science
Added: August 6, 2018

1998 journal article

Iron regulatory element and internal loop/bulge structure for ferritin mRNA studied by cobalt(III) hexammine binding, molecular modeling, and NMR spectroscopy

BIOCHEMISTRY, 37(6), 1505โ€“1512.

By: Z. Gdaniecโ€‰ n, H. Sierzputowska-Gracz n & E. Theil n

co-author countries: Poland ๐Ÿ‡ต๐Ÿ‡ฑ United States of America ๐Ÿ‡บ๐Ÿ‡ธ
MeSH headings : Animals; Anura; Binding Sites / drug effects; Binding Sites / genetics; Chlorides / metabolism; Chlorides / pharmacology; Cobalt / metabolism; Cobalt / pharmacology; Ferritins / genetics; Indicators and Reagents; Iron-Regulatory Proteins; Iron-Sulfur Proteins / chemistry; Iron-Sulfur Proteins / drug effects; Iron-Sulfur Proteins / genetics; Iron-Sulfur Proteins / metabolism; Magnetic Resonance Spectroscopy; Models, Molecular; Nucleic Acid Conformation; Protons; RNA, Messenger / chemistry; RNA, Messenger / metabolism; RNA-Binding Proteins / chemistry; RNA-Binding Proteins / drug effects; RNA-Binding Proteins / genetics; RNA-Binding Proteins / metabolism
Source: Web Of Science
Added: August 6, 2018

1998 journal article

Localized unfolding at the junction of three ferritin subunits - A mechanism for iron release?

JOURNAL OF BIOLOGICAL CHEMISTRY, 273(30), 18685โ€“18688.

By: H. Takagi, D. Shi, Y. Ha, N. Allewell & E. Theil*

MeSH headings : Amino Acid Substitution; Animals; Crystallography, X-Ray; Ferritins / genetics; Ferritins / metabolism; Iron / metabolism; Kinetics; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Folding; Ranidae; Spectrophotometry, Atomic; Structure-Activity Relationship
Source: Web Of Science
Added: August 6, 2018

1998 journal article

Loops and bulge/loops in iron-responsive element isoforms influence iron regulatory protein binding - Fine-tuning of mRNA regulation?

JOURNAL OF BIOLOGICAL CHEMISTRY, 273(37), 23637โ€“23640.

By: Y. Ke, J. Wu, E. Leibold, W. Walden & E. Theil*

MeSH headings : 5-Aminolevulinate Synthetase / genetics; Aconitate Hydratase / genetics; Animals; Base Composition; Base Sequence; Cloning, Molecular; Ferritins / genetics; Gene Expression Regulation; Iron Regulatory Protein 1; Iron Regulatory Protein 2; Iron-Regulatory Proteins; Iron-Sulfur Proteins / genetics; Iron-Sulfur Proteins / metabolism; Liver / metabolism; Nucleic Acid Conformation; RNA, Messenger / biosynthesis; RNA, Messenger / chemistry; RNA, Messenger / genetics; RNA-Binding Proteins / genetics; RNA-Binding Proteins / metabolism; Rabbits; Receptors, Transferrin / genetics; Recombinant Proteins / metabolism; Saccharomyces cerevisiae
Source: Web Of Science
Added: August 6, 2018

1998 patent

Methods of identifying transition metal complexes that selectively cleave regulatory elements of mRNA and uses thereof

Washington, DC: U.S. Patent and Trademark Office.

By: E. Theil

Source: NC State University Libraries
Added: August 6, 2018

1998 book

Principles of chemistry in biology: A teaching companion

Washington, DC: American Chemical Society; Distributed by Oxford University Press.

Source: NC State University Libraries
Added: August 6, 2018

1998 journal article

The iron responsive element (IRE) family of mRNA regulators: Regulation of iron transport and uptake compared in animals, plants, and microorganisms

Iron Transport and Storage in Microorganisms, Plants and Animals, 35(1998), 403โ€“434.

By: E. Theil

Source: NC State University Libraries
Added: August 6, 2018

1997 journal article

Preliminary analysis of amphibian red cell M ferritin in a novel tetragonal unit cell

ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY, 53, 513โ€“523.

By: Y. Ha*, E. Theil* & N. Allewellโ€‰*

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
Source: Web Of Science
Added: August 6, 2018

1997 journal article

Rapid and parallel formation of Fe3+ multimers, including a trimer, during H-type subunit ferritin mineralization

BIOCHEMISTRY, 36(25), 7917โ€“7927.

By: A. Pereiraโ€‰ n, P. Tavaresโ€‰ n, S. Lloydโ€‰ n, D. Danger n, D. Edmondson n, E. Theil n, B. Huynh n

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
MeSH headings : Animals; Anura; Biopolymers; Electron Spin Resonance Spectroscopy; Ferric Compounds / chemistry; Ferritins / chemistry; Minerals / chemistry; Oxidation-Reduction; Recombinant Proteins / chemistry; Spectroscopy, Mossbauer
Source: Web Of Science
Added: August 6, 2018

1997 journal article

Sustainable solution for dietary iron deficiency through plant biotechnology and breeding to increase seed ferritin control

European Journal of Clinical Nutrition, 51(Suppl. 4), S28โ€“31.

By: E. Theil, J. Burton & J. Beard

Source: NC State University Libraries
Added: August 6, 2018

1997 journal article

The influence of conserved tyrosine 30 and tissue-dependent differences in sequence on ferritin function: use of blue and purple Fe(III) species as reporters of ferroxidation

Journal of Biological Inorganic Chemistry, 2(5), 652โ€“661.

By: J. Fetter n, J. Cohenโ€‰*, D. Danger n, L. Sanders* & E. Theil n

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
Source: NC State University Libraries
Added: August 6, 2018

1997 chapter

Translational regulation of bioiron

In S. Silver & W. Walden (Eds.), Metal ions in gene regulation (pp. 131โ€“156).

By: E. Theil*

Ed(s): . S. Silver & W. Walden

Source: NC State University Libraries
Added: August 6, 2018

1990 journal article

Regulation of ferritin and transferrin receptor messenger-rnas

Journal of Biological Chemistry, 265(9), 4771โ€“4774.

By: E. Theil

Source: NC State University Libraries
Added: August 6, 2018

1987 review

FERRITIN - STRUCTURE, GENE-REGULATION, AND CELLULAR FUNCTION IN ANIMALS, PLANTS, AND MICROORGANISMS

[Review of ]. ANNUAL REVIEW OF BIOCHEMISTRY, 56, 289โ€“315.

By: E. Theil*

Source: Web Of Science
Added: August 6, 2018