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Works (67)
Updated: July 22nd, 2024 08:06
2024 journal article
Utilizing multiscale engineered biomaterials to examine <scp>TGF‐β</scp>‐mediated myofibroblastic differentiation
Wound Repair and Regeneration, 3.
author keywords: biomaterials; DNA origami; fibrosis; mechanotransduction; microgel; TGF-beta
TL;DR:
It is found that highly viscous materials with non-fixed TGF-β-R spacing promoted increased TGF-β signalling and myofibroblastic differentiation, likely due to the ability of cells to better cluster receptors on these surfaces.
(via Semantic Scholar)
doi.org (publisher)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: March 18, 2024
2022 journal article
DNA aerogels and DNA-wrapped CNT aerogels for neuromorphic applications
MATERIALS TODAY BIO, 16.
author keywords: DNA aerogel; DNA -wrapped CNT aerogel; Resistive switching; Neuromorphic application; Self -assembly
TL;DR:
The successful construction of pure DNA aerogels and DNA-wrapped carbon nanotube (CNT) composite (DNA-CNT), via a single-step freeze-drying of the respective hydrogels are described.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: September 27, 2022
2022 journal article
Modeling and characterization of stochastic resistive switching in single Ag2S nanowires
SCIENTIFIC REPORTS, 12(1).
UN Sustainable Development Goal Categories
11. Sustainable Cities and Communities
(Web of Science)
Source: Web Of Science
Added: May 16, 2022
2022 journal article
Resistive switching of two-dimensional Ag2S nanowire networks for neuromorphic applications
JOURNAL OF VACUUM SCIENCE & TECHNOLOGY B, 40(4).
UN Sustainable Development Goal Categories
11. Sustainable Cities and Communities
(Web of Science)
Source: Web Of Science
Added: June 27, 2022
2021 journal article
Mechanical and Electrical Properties of DNA Hydrogel-Based Composites Containing Self-Assembled Three-Dimensional Nanocircuits
APPLIED SCIENCES-BASEL, 11(5).
author keywords: DNA hydrogel; DNA hydrogel-based composites; self-assembly; biomaterials; DNA nanotechnology; carbon nanotubes; gold nanoparticles
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: March 22, 2021
2021 journal article
Multivalent Aptamer‐Functionalized Single‐Strand RNA Origami as Effective, Target‐Specific Anticoagulants with Corresponding Reversal Agents
Advanced Healthcare Materials, 10(11).
author keywords: anticoagulants; aptamers; direct thrombin inhibitors; nucleic acids; reversal agents; RNA nanotechnology; RNA origami
MeSH headings : Anticoagulants / pharmacology; Aptamers, Nucleotide / pharmacology; Blood Coagulation; RNA / pharmacology; Thrombin
TL;DR:
Compared to current commercial intravenous anticoagulants, RNA origami‐based molecules show promise as safer alternatives with rapid activity switching for future therapeutic applications.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, Crossref, NC State University Libraries
Added: June 10, 2021
2021 review
Self-Assembling Nucleic Acid Nanostructures Functionalized with Aptamers
[Review of ]. CHEMICAL REVIEWS, 121(22), 13797–13868.
MeSH headings : Nanostructures / chemistry; Nanotechnology; Nucleic Acid Conformation; Nucleic Acids / chemistry; Oligonucleotides
TL;DR:
This review focuses on the development of self-assembling nucleic acid nanostructures that are functionalized with nucleic Acid aptamers and their great potential in wide ranging application areas.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: March 7, 2022
2019 journal article
Genetically Encoded, Functional Single-Strand RNA Origami: Anticoagulant
ADVANCED MATERIALS, 31(21).
author keywords: anticoagulants; in vitro transcription; nucleic acid nanotechnology; RNA aptamers; RNA origami
MeSH headings : Anticoagulants / chemistry; Anticoagulants / pharmacology; Aptamers, Nucleotide / chemistry; Aptamers, Nucleotide / metabolism; Aptamers, Nucleotide / pharmacology; Humans; Nucleic Acid Conformation; Partial Thromboplastin Time; RNA / chemistry; RNA / pharmacology; Thrombin / antagonists & inhibitors; Thrombin / genetics; Thrombin / metabolism
TL;DR:
A family of self‐folding, functional RNA origami molecules bearing multiple thrombin‐binding RNA aptamers and showing significantly improved anticoagulant activity is described, paving the way for development of RNA Origami for potential therapeutic applications especially as a safer surgical anticogulant.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: July 29, 2019
2017 journal article
2Precise Coating of a Wide Range of DNA Templates by a Protein Polymer with a DNA Binding Domain
ACS NANO, 11(1), 144–152.
author keywords: directed self-assembly; protein engineering; DNA nanotechnology; single molecule; protein polymer; nanomaterials
MeSH headings : Binding Sites; DNA / chemistry; Models, Molecular; Nanostructures / chemistry; Nanotechnology; Peptides / chemical synthesis; Peptides / chemistry; Protein Conformation; Proteins / chemical synthesis; Proteins / chemistry
TL;DR:
Combining the programmability of DNA with the nonperturbing precise coating capability of the engineered protein C8-BSso7d holds promise for future applications such as the creation of DNA-protein hybrid networks, or the efficient transfection of individual DNA nanostructures into cells.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2017 journal article
Engineered Diblock Polypeptides Improve DNA and Gold Solubility during Molecular Assembly
ACS NANO, 11(1), 831–842.
author keywords: directed self-assembly; molecular assembly; protein engineering. DNA nanotechnology; protein polymer; diblock polypeptide; solution compatibilization
MeSH headings : DNA / chemistry; Gold / chemistry; Macromolecular Substances / chemistry; Metal Nanoparticles / chemistry; Microscopy, Atomic Force; Nanotechnology; Particle Size; Peptides / chemistry; Protein Engineering; Solubility; Surface Properties
TL;DR:
Initial data is presented showing that the diblock polypeptides promote the formation in the solution of desired organic/inorganic assemblies, as well as two 3D tetrahedral DNA origamis.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2017 journal article
Search for effective chemical quenching to arrest molecular assembly and directly monitor DNA nanostructure formation
NANOSCALE, 9(4), 1637–1644.
MeSH headings : DNA Replication; DNA, Single-Stranded / chemistry; Nanostructures / chemistry; Nanotechnology; Nucleic Acid Conformation
TL;DR:
The search for a robust new technique, chemical quenching, to arrest molecular folding in DNA systems for subsequent characterization is presented and two miniM13 origami designs based on a 2.4 kb scaffold are introduced to examine the relevance of design in the folding process.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2017 journal article
pH-Driven Actuation of DNA Origami via Parallel I-Motif Sequences in Solution and on Surfaces
BIOCONJUGATE CHEMISTRY, 28(7), 1821–1825.
MeSH headings : DNA / chemistry; Hydrogen-Ion Concentration; Image Processing, Computer-Assisted; Microscopy, Atomic Force; Nanotechnology / methods; Nucleic Acid Conformation; Nucleotide Motifs; Solutions; Surface Properties
TL;DR:
This study presents a new implementation of parallel I-motif actuators, emphasizing their future potential as drivers of complex internal motion between substructures and providing a useful step toward more complex and effective molecular machines.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Activatable tiles for compact robust programmable molecular assembly and other applications
Natural Computing, 15(4), 611–634.
author keywords: DNA self-assembly; Error correction; Tile assembly model; Strand displacement; Programmable molecular machines; Deprotection systems; Concentration systems; Reaction catalyzation
TL;DR:
A protection/deprotection strategy to strictly enforce the direction of tiling assembly growth so that the assembly process is robust against errors and the error rate can be decreased significantly with respect to Winfree's original kinetic tile assembly model.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy
(OpenAlex)
Source: Crossref
Added: November 29, 2020
2016 journal article
Competitive annealing of multiple DNA origami: formation of chimeric origami
NEW JOURNAL OF PHYSICS, 18.
author keywords: structural DNA nanotechnology; programmed molecular assembly; DNAorigami; chimeric origami
TL;DR:
This initial study shows that competitive anneals provide an exciting way to create diverse new nanostructures and may be used to examine the relative stability of various structural motifs.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
7. Affordable and Clean Energy
(OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Design of Potent and Controllable Anticoagulants Using DNA Aptamers and Nanostructures
MOLECULES, 21(2).
Contributors: A. Rangnekar n, J. Nash n, B. Goodfred n, Y. Yingling n & n
author keywords: thrombin; DNA aptamers; anticoagulation; DNA nanotechnology
MeSH headings : Anticoagulants / chemistry; Anticoagulants / pharmacology; Aptamers, Nucleotide / chemistry; Aptamers, Nucleotide / pharmacology; Drug Design; Drug Evaluation, Preclinical; Humans; Molecular Dynamics Simulation; Nanostructures / chemistry; Partial Thromboplastin Time
TL;DR:
By using DNA strand displacement, this work was able to turn the coagulation cascade off and on as desired, thereby enabling significantly better control over blood coagulating.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2015 journal article
An easy-to-prepare mini-scaffold for DNA origami
NANOSCALE, 7(40), 16621–16624.
MeSH headings : Bacteriophage M13 / chemistry; DNA, Single-Stranded / chemistry; DNA, Viral / chemistry
TL;DR:
A system is described that was designed approximately one third the length of the M13 bacteriophage genome for ease of ssDNA production and folding of the 2404-base ssDNA scaffold into a variety of origami shapes with high assembly yields is demonstrated.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2015 journal article
Comparative Incorporation of PNA into DNA Nanostructures
MOLECULES, 20(9), 17645–17658.
author keywords: peptide nucleic acid; oligonucleotide conjugates; modified oligonucleotides; DNA nanobiotechnology; nanomaterials
MeSH headings : Binding Sites; DNA / chemistry; DNA, Single-Stranded; Nanostructures / chemistry; Nucleic Acid Conformation; Peptide Nucleic Acids / chemistry
TL;DR:
The results show that PNA allows for toehold-free strand displacement and that incorporation yield depends critically on binding site geometry, which provides guidance for the design of PNA binding sites on nucleic acid nanostructures with an eye towards optimizing fabrication yield.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2015 journal article
Coverage percentage and raman measurement of cross-tile and scaffold cross-tile based DNA nanostructures
COLLOIDS AND SURFACES B-BIOINTERFACES, 135, 677–681.
author keywords: DNA self-assembley; Substrate-assisted growth; Coverage; Ion doping; Raman
MeSH headings : DNA / chemistry; Microscopy, Atomic Force; Nanostructures; Spectrum Analysis, Raman / methods
TL;DR:
Two free-solution annealed DNA nanostructures consisting of either cross-tile CT1 or CT2 are presented, which exhibit two distinct structural morphologies, with one-dimensional nanotubes for CT1 and 2D nanolattices for CT2.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2015 journal article
Directed Enzymatic Activation of 1-D DNA Tiles
ACS NANO, 9(2), 1072–1079.
author keywords: DNA self assembly; DNA Polymerase; DNA tile; directed assembly; sequential assembly
MeSH headings : DNA / chemistry; DNA-Directed DNA Polymerase / metabolism; Enzyme Activation; Nanostructures / chemistry; Nanotechnology / methods
TL;DR:
A simplified version of the Activatable tile assembly model is experimentally demonstrate the simultaneous assembly of protected DNA tiles and stepwise activated assembly where a set of inert tiles are activated sequentially one after another as a result of attachment to a growing 1-D assembly.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2015 journal article
Electronically addressable nanomechanical switching of i-motif DNA origami assembled on basal plane HOPG
Chemical Communications, 51(74), 14111–14114.
MeSH headings : DNA / chemistry; Electrochemical Techniques / methods; Electronics; Graphite / chemistry; Hydrogen-Ion Concentration; Nanostructures; Nanotechnology / methods; Nucleotide Motifs; Surface Properties
TL;DR:
Here, a pH-induced nanomechanical switching of i-motif structures incorporated into DNA origami bound onto cysteamine-modified basal plane HOPG was electronically addressed, demonstrating for the first time the electrochemical read-out of the Nanomechanics of DNA Origami.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: NC State University Libraries
Added: August 6, 2018
2014 review
Building DNA DNA Nanostructures for Molecular Computation, Templated Assembly, and Biological Applications
[Review of ]. ACCOUNTS OF CHEMICAL RESEARCH, 47(6), 1778–1788.
MeSH headings : Base Sequence; Biosensing Techniques; Computers, Molecular; DNA / chemistry; DNA, Single-Stranded / chemistry; Humans; Nanostructures / chemistry; Nanotechnology / methods; Nanowires
TL;DR:
The tremendous progress in DNA nanotechnology over the past three decades will open even more research avenues in the near future for applications in a wide variety of disciplines including electronics, photonics, biomedical engineering, biosensing, therapeutics, and nucleic-acid-based drug delivery.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2014 journal article
Programmable DNA tile self-assembly using a hierarchical sub-tile strategy
NANOTECHNOLOGY, 25(7).
author keywords: DNA self-assembly; DNA tile; sub-tile; structural DNA nanotechnology; programmable nanostructure
MeSH headings : Algorithms; DNA / analysis; DNA / chemistry; DNA, Single-Stranded / chemistry; Electrophoresis, Polyacrylamide Gel; Microscopy, Atomic Force; Nanostructures / chemistry; Nanotechnology; Nucleic Acid Conformation; Nucleic Acid Hybridization; Oligonucleotides / chemistry
TL;DR:
A new DNA 'sub-tile' strategy to easily create whole families of programmable tiles is reported to enable the rapid redesign and prototyping of complex DNA tile sets and tiles with asymmetric designs.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2014 journal article
Structural and thermodynamic analysis of modified nucleosides in self-assembled DNA cross-tiles
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 32(2), 319–329.
author keywords: DNA; DNA nanotechnology; molecular self-assembly; cruciform structures; lattices; modified nucleosides
MeSH headings : Base Pairing / genetics; Circular Dichroism; DNA / chemical synthesis; DNA / chemistry; DNA / ultrastructure; DNA, Single-Stranded; Microscopy, Atomic Force; Models, Molecular; Nucleic Acid Conformation; Nucleic Acid Denaturation; Nucleosides / chemistry; Thermodynamics
TL;DR:
Results strongly indicate the importance of a small number of centrally located unpaired nucleosides within the structures of DNA cross-tiles, particularly during thermal denaturation and circular dichroism spectroscopy.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2014 journal article
Surface-Enhanced Raman Scattering Plasmonic Enhancement Using DNA Origami-Based Complex Metallic Nanostructures
NANO LETTERS, 14(4), 2099–2104.
author keywords: DNA origami; Raman; SERS; 4-aminobenzenethiol
MeSH headings : DNA / chemistry; Dimerization; Gold / chemistry; Metal Nanoparticles / chemistry; Metal Nanoparticles / ultrastructure; Nanostructures / chemistry; Nanostructures / ultrastructure; Nucleic Acid Conformation; Spectrum Analysis, Raman / methods; Sulfanilic Acids / analysis; Surface Properties
TL;DR:
This work uses DNA origami templates to engineer surface-enhanced Raman scattering substrates and observes a significant Raman signal enhancement from molecules covalently attached to the assemblies, as compared to control nanoparticle samples that lack interparticle hot spots.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2014 journal article
Toward Larger DNA Origami
NANO LETTERS, 14(10), 5740–5747.
author keywords: Nanotechnology; structural DNA nanotechnology; DNA origami; lambda DNA; on-chip DNA synthesis
MeSH headings : Bacteriophage lambda / chemistry; DNA / chemical synthesis; DNA / chemistry; DNA, Viral / chemical synthesis; DNA, Viral / chemistry; Microscopy, Atomic Force; Nanostructures / chemistry; Nanostructures / ultrastructure; Nanotechnology / methods; Nucleic Acid Conformation
TL;DR:
Very efficient assembly of a 51-kilobasepair origami from the λ/M13 hybrid scaffold folded by chip-derived staple strands is experimentally demonstrated and two-dimensional, asymmetric origami sheets with controlled global curvature such that they land on a substrate in predictable orientations that have been verified by atomic force microscopy.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2013 journal article
An autonomously self-assembling dendritic DNA nanostructure for target DNA detection
BIOTECHNOLOGY JOURNAL, 8(2), 221–227.
author keywords: DNA sequence detection; Hybridization cascade; Molecular self-assembly; Nanobiotechnology; Nucleic acids
MeSH headings : Biosensing Techniques / instrumentation; Biosensing Techniques / methods; Chlamydia / isolation & purification; DNA / chemistry; DNA / isolation & purification; Electrophoresis, Polyacrylamide Gel; Gold / chemistry; HIV / isolation & purification; Metal Nanoparticles / chemistry; Nucleic Acid Conformation; Nucleic Acid Hybridization; Sequence Analysis, DNA / methods
TL;DR:
A DNA detection system employing the triggered self-assembly of a novel DNA dendritic nanostructure that has minimal sequence constraints, allowing reconfiguration for the detection of arbitrary target sequences.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2013 journal article
One-Pot Assembly of a Hetero-dimeric DNA Origami from Chip-Derived Staples and Double-Stranded Scaffold
ACS NANO, 7(2), 903–910.
author keywords: structural DNA nanotechnology; molecular self-assembly; DNA origami; chip-synthesized oligonucleotides; synthetic biology; gene-synthesis; inkjet
MeSH headings : DNA / chemistry; Dimerization; Formamides / chemistry; Models, Molecular; Nanostructures / chemistry; Nanotechnology / methods; Nucleic Acid Conformation; Oligonucleotide Array Sequence Analysis / methods
TL;DR:
A single-pot reaction where both strands of double-stranded M13-bacteriophage DNA are simultaneously folded into two distinct shapes that then heterodimerize with high yield markedly increases the useful scale of DNA origami.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2013 review
Overview of DNA origami for molecular self-assembly
[Review of ]. WILEY INTERDISCIPLINARY REVIEWS-NANOMEDICINE AND NANOBIOTECHNOLOGY, 5(2), 150–162.
MeSH headings : DNA / chemistry; Nanostructures / chemistry; Nanotechnology; Nucleic Acid Conformation
TL;DR:
This review will discuss the development of concepts and methods involved in DNA origami with an eye toward future increases in origami size and sequence complexity, as well as exploring different methods for the production of the DNA molecular components.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2013 journal article
Sensitization of Transforming Growth Factor-beta Signaling by Multiple Peptides Patterned on DNA Nanostructures
BIOMACROMOLECULES, 14(12), 4157–4160.
MeSH headings : Animals; Biotin / chemistry; Cell Line; DNA / chemistry; Drug Carriers / chemistry; Drug Carriers / pharmacology; Genes, Reporter; Mice; Nanostructures / chemistry; Nanostructures / ultrastructure; Peptide Fragments / chemistry; Peptide Fragments / pharmacology; Receptors, Transforming Growth Factor beta / metabolism; Signal Transduction; Streptavidin / chemistry; Transforming Growth Factor beta / pharmacology; Transforming Growth Factor beta / physiology
TL;DR:
This work reports sensitization of a cellular signaling pathway by addition of functionalized DNA nanostructures, an important initial step toward realization of DNA as a self-assembling and biologically compatible material for use in tissue engineering and drug delivery.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2012 journal article
DNA nanotube formation based on normal mode analysis
Nanotechnology, 23(10), 105704.
MeSH headings : Computer Simulation; DNA / chemistry; DNA / ultrastructure; Models, Molecular; Nanotechnology / methods; Nanotubes / chemistry; Nanotubes / ultrastructure
TL;DR:
A theoretical study on why uncorrugated cross tiles self-assemble into counterintuitive 3D nanotube structures and not planar 2D lattices is presented.
(via Semantic Scholar)
Source: Crossref
Added: August 28, 2020
2012 journal article
Fabrication of zigzag and folded DNA nanostructures by an angle control scheme
Soft Matter, 8(1), 44–47.
Source: Crossref
Added: August 28, 2020
2012 journal article
Increased anticoagulant activity of thrombin-binding DNA aptamers by nanoscale organization on DNA nanostructures
Nanomedicine: Nanotechnology, Biology and Medicine, 8(5), 673–681.
author keywords: Thrombin; DNA aptamers; Anticoagulation; DNA nanotechnology; DNA weave-tile
MeSH headings : Anticoagulants / chemistry; Anticoagulants / pharmacology; Aptamers, Nucleotide / chemistry; Aptamers, Nucleotide / pharmacology; Blood Coagulation / drug effects; DNA / chemistry; Humans; Nanostructures / chemistry; Plasma / chemistry; Thrombin / antagonists & inhibitors; Thrombin / chemistry
TL;DR:
Thrombin-binding DNA aptamers were further optimized by nanoscale organization on DNA nanostructures, which is a multi-aptamer inhibitor with activity eightfold higher than that of free aptamer.
(via Semantic Scholar)
Source: Crossref
Added: August 28, 2020
2011 journal article
Connecting the Nanodots: Programmable Nanofabrication of Fused Metal Shapes on DNA Templates
Nano Letters, 11(8), 3489–3492.
author keywords: Nanoparticles; electroless deposition; DNA origami; self-assembly; nanofabrication; metallization
MeSH headings : DNA / chemistry; Gold / chemistry; Metal Nanoparticles; Templates, Genetic
TL;DR:
This work presents a novel method for producing complex metallic nanostructures of programmable design, using DNA origami templates modified to have DNA binding sites with a uniquely coded sequence to be adsorbed onto silicon dioxide substrates.
(via Semantic Scholar)
Source: Crossref
Added: August 28, 2020
2011 journal article
Design and Construction of Double-Decker Tile as a Route to Three-Dimensional Periodic Assembly of DNA
Journal of the American Chemical Society, 133(11), 3843–3845.
MeSH headings : DNA / chemistry; Microscopy, Atomic Force; Nucleic Acid Conformation
TL;DR:
The design and construction of a novel DNA cross tile, called the double-decker tile, which can be programmed to form a three-dimensional periodic lattice with large cavities that could be used as a scaffold for precise positioning of molecules in space.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
11. Sustainable Cities and Communities
(OpenAlex)
Source: Crossref
Added: August 28, 2020
2011 journal article
Design and synthesis of DNA four-helix bundles
Nanotechnology, 22(23), 235601.
MeSH headings : DNA / chemistry; Microscopy, Atomic Force; Nanostructures / chemistry; Nanostructures / ultrastructure; Nanotechnology / methods; Nucleic Acid Conformation
TL;DR:
The design and synthesis of a DNA four-helix bundle was found to be extremely rigid and stable and provides an exciting prospect for making programmable circular nanostructures using DNA.
(via Semantic Scholar)
Source: Crossref
Added: August 28, 2020
2011 journal article
Intrinsic DNA curvature of double-crossover tiles
Nanotechnology, 22(24), 245706.
MeSH headings : Base Sequence; DNA / chemistry; DNA / genetics; DNA / ultrastructure; Microscopy, Atomic Force; Molecular Sequence Data
TL;DR:
A theoretical model which takes into account the structural distortion of double-crossover DNA tiles has been studied and it has been found that a single vector appropriately describes the curvature of the tiles, of which a higher magnitude hinders lattice growth.
(via Semantic Scholar)
Source: Crossref
Added: August 28, 2020
2011 journal article
Organization of Inorganic Nanomaterials via Programmable DNA Self-Assembly and Peptide Molecular Recognition
ACS Nano, 5(3), 2200–2205.
author keywords: molecular self-assembly; structural DNA nanotechnology; molecular recognition; GEPI; oligonucleotide; oligopeptide
MeSH headings : Biomimetic Materials / chemistry; DNA / chemistry; DNA / ultrastructure; Inorganic Chemicals / chemistry; Macromolecular Substances / chemistry; Materials Testing; Molecular Conformation; Nanostructures / chemistry; Nanostructures / ultrastructure; Particle Size; Peptides / chemistry; Protein Binding; Surface Properties
TL;DR:
This work provides experimental proof that a single peptide molecule is sufficient for immobilization of a nanoparticle, and can be thought of as programmable, granular, artificial biomineralization.
(via Semantic Scholar)
Source: Crossref
Added: August 28, 2020
2011 journal article
Self-assembling DNA templates for programmed artificial biomineralization
Soft Matter, 7(7), 3240.
Source: Crossref
Added: August 28, 2020
2010 journal article
In situ Synthesis of DNA Microarray on Functionalized Cyclic Olefin Copolymer Substrate
ACS Applied Materials & Interfaces, 2(2), 491–497.
author keywords: DNA microarray; DNA synthesis; COC; synthetic biology; microfluidics; DNA origami
MeSH headings : Cycloparaffins / chemistry; DNA / analysis; DNA / chemistry; DNA / genetics; Equipment Design; Equipment Failure Analysis; Membranes, Artificial; Oligonucleotide Array Sequence Analysis / instrumentation; Polymers / chemistry
TL;DR:
A new method was developed that enabled for the first time in situ synthesis of DNA oligonucleotide microarrays on the COC substrate, and it was demonstrated that pools of high-quality mixed-oligos could be cleaved off the SiO(2)-COCmicroarrays and used directly for construction of DNA origami nanostructures.
(via Semantic Scholar)
Source: Crossref
Added: August 28, 2020
2010 journal article
Weave Tile Architecture Construction Strategy for DNA Nanotechnology
Journal of the American Chemical Society, 132(41), 14481–14486.
MeSH headings : Base Sequence; DNA / chemistry; Microscopy, Atomic Force; Molecular Sequence Data; Nanotechnology
TL;DR:
The design, implementation, and testing of a unique architectural strategy incorporating some aspects of each of the two previous design categories but without multi-arm junction motifs is described, resulting in a structurally flexible tile that can be used to increase the anticoagulant activity of thrombin-binding aptamers in vitro.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
11. Sustainable Cities and Communities
(OpenAlex)
Source: Crossref
Added: August 28, 2020
2009 journal article
Another dimension for DNA art
Nature, 459(7245), 331–332.
MeSH headings : Bacteriophage M13 / genetics; Base Pairing; Computer-Aided Design; DNA / chemistry; DNA / genetics; Nanostructures / chemistry; Nanotechnology / instrumentation; Nanotechnology / methods; Sculpture
TL;DR:
Efforts to mimic these assembly processes enter a new phase with a method to design and build three-dimensional DNA nanostructures.
(via Semantic Scholar)
Source: Crossref
Added: January 21, 2021
2009 journal article
Nanofabrication by DNA self-assembly
Materials Today, 12(5), 24–32.
Source: Crossref
Added: August 28, 2020
2008 journal article
A DNA Nanotransport Device Powered by Polymerase ϕ29
Nano Letters, 8(11), 3870–3878.
MeSH headings : Bacillus Phages / enzymology; DNA / chemistry; DNA / metabolism; DNA-Directed DNA Polymerase / metabolism; Fluorescence Resonance Energy Transfer; Nanostructures / chemistry
TL;DR:
This paper presents a method to exploit a strand-displacing polymerase phi29 as a driving force for nanoscale transportation devices and demonstrates transportation of a DNA cargo on a DNA track with the help of fluorescence resonance electron transfer data.
(via Semantic Scholar)
Source: Crossref
Added: August 28, 2020
2008 chapter
Activatable Tiles: Compact, Robust Programmable Assembly and Other Applications
In DNA Computing (pp. 15–25).
TL;DR:
A novel protection/deprotection strategy to strictly enforce the direction of tiling assembly growth to ensure the robustness of the assembly process.
(via Semantic Scholar)
Source: Crossref
Added: August 28, 2020
2008 journal article
Plasmon coupling in binary metal core–satellite assemblies
Applied Physics B, 93(1), 69–78.
Source: Crossref
Added: August 28, 2020
2008 journal article
Reconfigurable Core−Satellite Nanoassemblies as Molecularly-Driven Plasmonic Switches
Nano Letters, 8(7), 1803–1808.
MeSH headings : Base Sequence; Computer Simulation; DNA / chemistry; Microscopy, Electron, Transmission; Models, Chemical; Molecular Sequence Data; Nanostructures / chemistry; Nanostructures / ultrastructure; Spectrum Analysis; Surface Plasmon Resonance
TL;DR:
A strong correspondence between measured and simulated difference spectra validates the structural models that link the observed plasmon modulation with DNA nanostructure reconfiguration.
(via Semantic Scholar)
Source: Crossref
Added: August 28, 2020
2008 journal article
Single-electron transistors made by chemical patterning of silicon dioxide substrates and selective deposition of gold nanoparticles
Applied Physics Letters, 93(12), 123101.
Source: Crossref
Added: August 28, 2020
2008 journal article
Stepwise Self-Assembly of DNA Tile Lattices Using dsDNA Bridges
Journal of the American Chemical Society, 130(1), 40–41.
MeSH headings : Crystallization; DNA / chemistry; Microscopy, Atomic Force; Nanostructures; Nanotechnology / methods; Nucleic Acid Conformation
TL;DR:
This letter demonstrates construction of superstructures consisting of heterogeneous DNA motifs using dsDNA in conjunction with more complex, cross-tile building blocks, constructed and visualized by high-resolution, liquid-phase atomic force microscopy.
(via Semantic Scholar)
Source: Crossref
Added: August 28, 2020
2007 chapter
Autonomous Programmable Biomolecular Devices Using Self-assembled DNA Nanostructures
In Logic, Language, Information and Computation (pp. 297–306).
Source: Crossref
Added: August 28, 2020
2007 journal article
Constructing novel materials with DNA
Nano Today, 2(2), 26–35.
TL;DR:
DNA, apart from being a natural biological information carrier, has also been recognized as a useful building material in the field of nanotechnology and is an appealing candidate for the construction of novel nanomaterials.
(via Semantic Scholar)
Source: Crossref
Added: August 28, 2020
2007 journal article
Engineering novel synthetic biological systems
IET Synthetic Biology, 1(1), 48–52.
TL;DR:
The engineering of four novel synthetic biological systems, one of which is a Bacterial Dynamo, for generating electricity using modified magnetotactic bacteria on a microfabricated device, and Human Encryption, an information encoding, storage, and retrieval scheme for potential security and medical diagnostic applications, are reported.
(via Semantic Scholar)
Source: Crossref
Added: August 28, 2020
2006 journal article
DNA bulks up
Nature Materials, 5(10), 767–768.
MeSH headings : Crystallization / methods; DNA / chemistry; DNA / ultrastructure; Hydrogels / chemistry; Nanostructures / chemistry; Nanostructures / ultrastructure
TL;DR:
A hydrogel made entirely of DNA is presented, which brings this molecule into the realm of bulk materials.
(via Semantic Scholar)
Source: Crossref
Added: January 21, 2021
2006 chapter
Design and Simulation of Self-repairing DNA Lattices
In DNA Computing (pp. 195–214).
TL;DR:
This work uses a special class of DNA tiling designs called reversible tiling which when carefully designed can provide inherent self-repairing capabilities to patterned DNA lattices and can transform any irreversible computational DNA tile set to its reversible counterpart and hence improve the self- repairability of the computational lattice.
(via Semantic Scholar)
Source: Crossref
Added: August 28, 2020
2006 journal article
Finite-Size, Fully Addressable DNA Tile Lattices Formed by Hierarchical Assembly Procedures
Angewandte Chemie International Edition, 45(5), 735–739.
author keywords: DNA structures; nanostructures; nanotechnology; self-assembly; supramolecular chemistry
MeSH headings : DNA / chemistry; Nanostructures / chemistry; Oligonucleotide Array Sequence Analysis / instrumentation; Particle Size
TL;DR:
Higher production yields of defect-free assemblies were achieved by procedures that minimize assembly depth (and maximize diversity of address labels) and some observations on scaling of these strategies to larger arrays are also presented.
(via Semantic Scholar)
Source: Crossref
Added: August 28, 2020
2006 journal article
Finite-Size, Fully Addressable DNA Tile Lattices Formed by Hierarchical Assembly Procedures
Angewandte Chemie International Edition, 45(40), 6607–6607.
Source: Crossref
Added: August 28, 2020
2006 journal article
Optimized fabrication and electrical analysis of silver nanowires templated on DNA molecules
Applied Physics Letters, 89(3), 033901.
TL;DR:
DNA templated functional nanowires may, in the near future, be targeted to connect at specific locations on larger-scale circuits and represent a potential breakthrough in the self-assembly of nanometer-scale structures for electronics layout.
(via Semantic Scholar)
Source: Crossref
Added: August 28, 2020
2006 journal article
Single-chain antibodies against DNA aptamers for use as adapter molecules on DNA tile arrays in nanoscale materials organization
Organic & Biomolecular Chemistry, 4(18), 3420.
MeSH headings : Antibodies / immunology; Antibodies / metabolism; Antibodies / ultrastructure; Aptamers, Nucleotide / genetics; Aptamers, Nucleotide / immunology; Aptamers, Nucleotide / metabolism; Bacteriophages; Base Sequence; DNA / metabolism; Immunoglobulin Variable Region / immunology; Microarray Analysis / instrumentation; Microarray Analysis / methods; Microscopy, Atomic Force; Molecular Sequence Data; Nanostructures / chemistry; Peptide Library; SELEX Aptamer Technique
TL;DR:
The decoration of various DNA tile structures with aptamers and binding of the selected single-chain antibody are demonstrated as well as the self-assembly of mixed DNA-protein biomolecular lattices.
(via Semantic Scholar)
Source: Crossref
Added: August 28, 2020
2005 journal article
DNA-programmed assembly of nanostructures
Organic & Biomolecular Chemistry, 3(22), 4023.
MeSH headings : DNA / chemistry; DNA / genetics; DNA / ultrastructure; Hydrogen Bonding; Nanostructures; Nucleic Acid Conformation
TL;DR:
The emerging field of DNA-nanotechnology is now exploring DNA-programmed processes for the assembly of organic compounds, biomolecules, and inorganic materials.
(via Semantic Scholar)
Source: Crossref
Added: August 28, 2020
2005 chapter
Design, Simulation, and Experimental Demonstration of Self-assembled DNA Nanostructures and Motors
In Lecture Notes in Computer Science (pp. 173–187).
TL;DR:
The evolution of DNA self-assembly techniques from pure theory, through simulation and design, and then to experimental practice is overviewed, along with an overview of theoretical models and algorithms for DNA lattice self- assembly.
(via Semantic Scholar)
Source: Crossref
Added: August 28, 2020
2005 journal article
Programmable DNA Self-Assemblies for Nanoscale Organization of Ligands and Proteins
Nano Letters, 5(4), 729–733.
MeSH headings : DNA / chemistry; DNA / ultrastructure; Ligands; Microscopy, Atomic Force; Nanostructures / chemistry; Nanotechnology / methods; Proteins / chemistry; Templates, Genetic
TL;DR:
The application of two self-assembled periodic DNA structures, two-dimensional nanogrids, and one-dimensional Nanotrack, as template for programmable self-assembly of streptavidin protein arrays with controlled density is reported.
(via Semantic Scholar)
Source: Crossref
Added: August 28, 2020
2005 journal article
Three-Helix Bundle DNA Tiles Self-Assemble into 2D Lattice or 1D Templates for Silver Nanowires
Nano Letters, 5(4), 693–696.
MeSH headings : DNA / chemistry; DNA / ultrastructure; Microscopy, Atomic Force; Nanostructures / chemistry; Nucleic Acid Conformation; Silver / chemistry
TL;DR:
A DNA nanostructure, the three-helix bundle (3HB), which consists of three double helical DNA domains connected by six immobile crossover junctions such that the helix axes are not coplanar is presented.
(via Semantic Scholar)
Source: Crossref
Added: August 28, 2020
2004 journal article
Bionanotechnology: Lessons from Nature. By David S Goodsell. Hoboken (New Jersey): Wiley‐Liss. $79.95. xii + 337 p; ill.; index. ISBN: 0–471–41719–X. 2004.
The Quarterly Review of Biology, 79(4), 415–415.
Source: Crossref
Added: January 21, 2021
2004 journal article
DNA nanotubes self-assembled from triple-crossover tiles as templates for conductive nanowires
Proceedings of the National Academy of Sciences, 101(3), 717–722.
MeSH headings : Base Sequence; DNA / chemical synthesis; DNA / chemistry; DNA / ultrastructure; Electric Conductivity; In Vitro Techniques; Metals; Microscopy, Atomic Force; Microscopy, Electron; Microscopy, Electron, Scanning; Nanotechnology; Nanotubes / chemistry; Nanotubes / ultrastructure; Sulfhydryl Compounds / chemistry
TL;DR:
DNA nanotubes represent a potential breakthrough in the self-assembly of nanometer-scale circuits for electronics layout because they can be targeted to connect at specific locations on larger-scale structures and can subsequently be metallized to form nanometers-scale wires.
(via Semantic Scholar)
Source: Crossref
Added: August 28, 2020
2004 journal article
DNA-Templated Self-Assembly of Protein and Nanoparticle Linear Arrays
Journal of the American Chemical Society, 126(2), 418–419.
MeSH headings : Biotin / chemistry; DNA / chemistry; DNA / genetics; DNA / metabolism; Gold / chemistry; Microscopy, Atomic Force; Nanotechnology / methods; Nucleic Acid Conformation; Particle Size; Streptavidin / chemistry
TL;DR:
An experiment using a linear array of DNA triple crossover tiles to controllably template the self-assembly of single-layer or double-layer linear arrays of streptavidin molecules and streptavin-conjugated nanogold particles through biotin-streptavid in interaction is reported.
(via Semantic Scholar)
Source: Crossref
Added: August 28, 2020
2004 journal article
Electronic nanostructures templated on self-assembled DNA scaffolds
Nanotechnology, 15(10), S525–S527.
Source: Crossref
Added: August 28, 2020
2004 journal article
Surface-Initiated Polymerization on Nanopatterns Fabricated by Electron-Beam Lithography
Advanced Materials, 16(23-24), 2141–2145.
Source: Crossref
Added: August 28, 2020
2003 chapter
DNA-based Cryptography
In Aspects of Molecular Computing (pp. 167–188).
TL;DR:
Some procedures for DNA-based cryptography based on one-time-pads that are in principle unbreakable are presented, and a class of DNA steganography systems, which secretly tag the input DNA and then hide it within collections of other DNA are examined.
(via Semantic Scholar)
Source: Crossref
Added: August 28, 2020
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