Works (5)

2020 journal article

Characterization of Cas12a nucleases reveals diverse PAM profiles between closely-related orthologs

NUCLEIC ACIDS RESEARCH, 48(10), 5624–5638.

By: T. Jacobsen, F. Ttofali, C. Liao*, S. Manchalu*, B. Gray* & C. Beisel

Source: Web Of Science
Added: October 5, 2020

2020 journal article

Tunable self-cleaving ribozymes for modulating gene expression in eukaryotic systems

PLOS ONE, 15(4).

By: T. Jacobsen, G. Yi n, H. Al Asafen n, A. Jermusyk n, C. Beisel & G. Reeves

Source: Web Of Science
Added: June 22, 2020

2019 journal article

The Acidaminococcus sp. Cas12a nuclease recognizes GTTV and GCTV as non-canonical PAMs


By: T. Jacobsen, C. Liao* & C. Beisel

author keywords: Cas nuclease; Cpf1; CRISPR-Cas systems; PAM; TIDE; TXTL
Source: Web Of Science
Added: September 9, 2019

2018 journal article

Rapid and Scalable Characterization of CRISPR Technologies Using an E. coli Cell-Free Transcription-Translation System

MOLECULAR CELL, 69(1), 146-+.

By: R. Marshall*, C. Maxwell n, S. Collins, T. Jacobsen, M. Luo n, M. Begemann*, B. Gray*, E. January* ...

Source: Web Of Science
Added: August 6, 2018

2017 journal article

A facilitated diffusion mechanism establishes the Drosophila Dorsal gradient

DEVELOPMENT, 144(23), 4450–4461.

By: S. Carrell, . Michael D. O'Connell, T. Jacobsen, A. Pomeroy n, S. Hayes n & G. Reeves

author keywords: Morphogen; Tissue patterning; Mathematical modeling; Dorsal; Cactus; Shuttling
Source: Web Of Science
Added: August 6, 2018