Theodore J. Morgan

Works (10)

Updated: August 4th, 2023 21:15

2006 journal article

High-resolution mapping of quantitative trait loci affecting increased life span in Drosophila melanogaster

GENETICS, 173(3), 1455–1463.

By: R. Wilson n, T. Morgan n & T. Mackay n

MeSH headings : Animals; Chromosome Mapping / methods; Drosophila melanogaster / genetics; Female; Genetic Complementation Test; Genetic Variation; Longevity / genetics; Male; Quantitative Trait Loci
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Source: Web Of Science
Added: August 6, 2018

2006 journal article

Phenotypic variation and natural selection at Catsup, a pleiotropic quantitative trait gene in Drosphila

CURRENT BIOLOGY, 16(9), 912–919.

By: M. Carbone n, K. Jordan n, R. Lyman n, S. Harbison  n, J. Leips*, T. Morgan n, M. DeLuca n, P. Awadalla n, T. Mackay n

MeSH headings : Animals; Catecholamines / metabolism; Drosophila / anatomy & histology; Drosophila / genetics; Drosophila Proteins / chemistry; Drosophila Proteins / genetics; Drosophila melanogaster / anatomy & histology; Drosophila melanogaster / genetics; Female; Genetic Variation; Genotype; Longevity / genetics; Male; Molecular Sequence Data; Motor Activity / genetics; Phenotype; Quantitative Trait Loci; Quantitative Trait, Heritable; Selection, Genetic
TL;DR: Molecular population genetic analyses of Catsup sequences are consistent with balancing selection maintaining multiple functional polymorphisms and identify potentially functional variants in protein coding regions that have large effects and are not common. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

2006 journal article

Pleiotropic fitness effects of the Tre1-Gr5a region in Drosophila melanogaster

NATURE GENETICS, 38(7), 824–829.

By: S. Rollmann n, M. Magwire n, T. Morgan n, E. Ozsoy n, A. Yamamoto n, T. Mackay n, R. Anholt n

MeSH headings : Animals; DNA Transposable Elements / genetics; DNA, Intergenic / genetics; Drosophila Proteins / genetics; Drosophila melanogaster / genetics; Drosophila melanogaster / physiology; Epistasis, Genetic; Female; Genes, Insect; Insulin / metabolism; Longevity / genetics; Male; Mutation; Phenotype; Quantitative Trait, Heritable; Receptors, Cell Surface / genetics; Receptors, G-Protein-Coupled / genetics; Repetitive Sequences, Nucleic Acid; Signal Transduction; Taste / genetics
TL;DR: It is demonstrated that single P-element insertions in the intergenic region between the gustatory receptor 5a and trapped in endoderm 1, which encodes an orphan receptor, exert complex pleiotropic effects on fitness traits, including selective nutrient intake, life span, and resistance to starvation and heat stress. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

2006 journal article

Quantitative genomics of aggressive behavior in Drosophila melanogaster

PLOS GENETICS, 2(9), 1386–1395.

By: A. Edwards n, S. Rollmann n, T. Morgan n & T. Mackay n

MeSH headings : Aggression; Animals; Behavior, Animal; DNA Transposable Elements / genetics; Drosophila melanogaster / genetics; Drosophila melanogaster / physiology; Genes, Insect; Genomics / methods; Mutagenesis, Insertional; Phenotype; Selection, Genetic; Transcription, Genetic
TL;DR: An assay to rapidly quantify aggressive behavior in Drosophila melanogaster is developed, and replicate selection lines with divergent levels of aggression are generated, and 15 novel genes affecting aggressive behavior are identified. (via Semantic Scholar)
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15. Life on Land (Web of Science)
Source: Web Of Science
Added: August 6, 2018

2006 journal article

Quantitative trait loci for thermotolerance phenotypes in Drosophila melanogaster

HEREDITY, 96(3), 232–242.

By: T. Morgan n & T. Mackay  n

author keywords: chill-coma recovery; environmental stress; heat-stress resistance; temperature stress; QTL
MeSH headings : Adaptation, Physiological / genetics; Animals; Cold Temperature; Drosophila melanogaster / genetics; Genetic Variation; Hot Temperature; Phenotype; Quantitative Trait Loci
TL;DR: A mapping population of recombinant inbred lines is used to map quantitative trait loci (QTL) that affect variation in both heat- and cold-stress resistance in D. melanogaster, suggesting that overlapping but generally unique genetic architectures underlie resistance to low- and high-temperature extremes. (via Semantic Scholar)
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13. Climate Action (Web of Science)
15. Life on Land (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2005 article

Genetics and genomics of Drosophila mating behavior

Mackay, T. F. C., Heinsohn, S. L., Lyman, R. F., Moehring, A. J., Morgan, T. J., & Rollmann, S. M. (2005, May 3). PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Vol. 102, pp. 6622–6629.

By: T. Mackay n, S. Heinsohn n, R. Lyman n, A. Moehring n, T. Morgan n & S. Rollmann n

MeSH headings : Animals; Chromosomes; Copulation / physiology; Drosophila melanogaster / genetics; Drosophila melanogaster / physiology; Female; Genes, Insect / genetics; Genomics; Male; Phenotype; Sexual Behavior, Animal / physiology; Transcription, Genetic / genetics
TL;DR: Drosophila melanogaster was subjected to 29 generations of replicated divergent artificial selection for mating speed, and the phenotypic response to selection was highly asymmetrical in the direction of reduced mating speed. (via Semantic Scholar)
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15. Life on Land (Web of Science)
Source: Web Of Science
Added: August 6, 2018

2005 journal article

Molecular and quantitative genetic divergence among populations of house mice with known evolutionary histories

Heredity, 94(5), 518–525.

By: T. Morgan, M. Evans, T. Garland, J. Swallow & P. Carter

Source: NC State University Libraries
Added: August 6, 2018

2003 journal article

Ontogenies in mice selected for high voluntary wheel-running activity. I. Mean ontogenies

EVOLUTION, 57(3), 646–657.

By: T. Morgan*, T. Garland * & P. Carter*

author keywords: artificial selection; body mass; correlated characters; food consumption; ontogeny; wheel running
MeSH headings : Analysis of Variance; Animals; Female; Male; Mice / classification; Mice / genetics; Mice, Inbred ICR; Motor Activity / genetics; Phylogeny; Running; Selection, Genetic; Sex Characteristics
TL;DR: Overall the results demonstrate strong effects of early‐age selection, genetic drift, and environmental variation on the evolution and expression of behavioral and morphological ontogenies, with selection changing not only the position of the morphologicalOntogeny but both the position and shape of the behavioral ontogeny. (via Semantic Scholar)
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UN Sustainable Development Goal Categories
13. Climate Action (Web of Science)
15. Life on Land (Web of Science)
Source: Web Of Science
Added: August 6, 2018

2003 journal article

The mode of evolution of molecular markers in populations of house mice under artificial selection for locomotor behavior

JOURNAL OF HEREDITY, 94(3), 236–242.

By: T. Morgan*, T. Garland, B. Irwin, J. Swallow & P. Carter

MeSH headings : Animals; Biological Evolution; Crosses, Genetic; Female; Gene Frequency; Genetic Markers; Genetic Variation; Genotype; Isoenzymes / genetics; Male; Mice; Mice, Inbred ICR; Microsatellite Repeats; Motor Activity / genetics
TL;DR: The results generally provide support for the neutral evolution of molecular markers, and the pattern of change of allele frequencies between the base population and generation 14 was largely in agreement with expectations under neutral evolution. (via Semantic Scholar)
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UN Sustainable Development Goal Categories
15. Life on Land (Web of Science)
Source: Web Of Science
Added: August 6, 2018

journal article

Quantitative genomics of locomotor behavior in Drosophila melanogaster

Jordan, K. W., Carbone, M. A., Yamamoto, A., Morgan, T. J., & Mackay, T. F. Genome Biology, 8(8).

By: K. Jordan, M. Carbone, A. Yamamoto, T. Morgan & T. Mackay

Source: NC State University Libraries
Added: August 6, 2018

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