@article{vaden_mathews_yoo_williams_harris_secoura_robertson_gleason_reynolds_piedrahita_2022, title={The use of autologous skeletal muscle progenitor cells for adjunctive treatment of presumptive urethral sphincter mechanism incompetence in female dogs}, volume={8}, ISSN={["1939-1676"]}, url={http://dx.doi.org/10.1111/jvim.16505}, DOI={10.1111/jvim.16505}, abstractNote={Abstract}, journal={JOURNAL OF VETERINARY INTERNAL MEDICINE}, publisher={Wiley}, author={Vaden, Shelly L. and Mathews, Kyle G. and Yoo, James and Williams, James Koudy and Harris, Tonya and Secoura, Patty and Robertson, James and Gleason, Katherine L. and Reynolds, Hannah and Piedrahita, Jorge}, year={2022}, month={Aug} }
 @article{gin_secoura_harris_vaden_2020, title={Outcomes Following Balloon Dilation of Benign Urethral Strictures in Dogs: Eight Cases (2005-2018)}, volume={56}, ISSN={["1547-3317"]}, DOI={10.5326/JAAHA-MS-6935}, abstractNote={ABSTRACT}, number={1}, journal={JOURNAL OF THE AMERICAN ANIMAL HOSPITAL ASSOCIATION}, author={Gin, Taylor Estes and Secoura, Patty and Harris, Tonya and Vaden, Shelly}, year={2020}, pages={23–29} }
 @article{von dollen_jones_beachler_harris_papich_lyle_bailey_2019, title={Antimicrobial Activity of Ceftiofur and Penicillin With Gentamicin Against Escherichia coli and Streptococcus equi Subspecies zooepidemicus in an Ex Vivo Model of Equine Postpartum Uterine Disease}, volume={79}, ISSN={["1542-7412"]}, DOI={10.1016/j.jevs.2019.06.005}, abstractNote={The use of antimicrobials for the management of equine uterine disease is commonplace, with antibiotic selection generally based on empirical evidence or in vitro sensitivity results. However, the potential disconnect between these laboratory results and clinical efficacy in the mare raises concern for antibiotic failure and subsequent development of resistant organisms. In this work, we attempt to bridge this gap by using an ex vivo model of the equine postpartum uterus to quantitatively evaluate the antimicrobial activity of two commonly used antibiotic treatments in the mare (ceftiofur and penicillin with gentamicin). The activity of both of these treatments was evaluated in two different fluid environments (standard bacterial culture broth and equine postpartum uterine fluid) against clinical isolates of E. coli and S. zooepidemicus. Although treatment with ceftiofur was effective at reducing growth of S. zooepidemicus in equine postpartum uterine fluid, it did not reduce bacterial growth of E. coli. Treatment with procaine penicillin G with gentamicin achieved at least bacteriostatic activity against E. coli in both fluid types, and bactericidal activity against S. zooepidemicus in both fluid types. The intrauterine infusion of procaine penicillin G with gentamicin in cases of postpartum uterine disease caused by E. coli or S. zooepidemicus is supported by the results of this work.}, journal={JOURNAL OF EQUINE VETERINARY SCIENCE}, author={Von Dollen, Karen A. and Jones, Monica and Beachler, Theresa and Harris, Tonya L. and Papich, Mark G. and Lyle, Sara K. and Bailey, C. Scott}, year={2019}, month={Aug}, pages={121–126} }
 @article{gould_klos_price_harris_vaden_tolbert_2018, title={Retrospective analysis of the effect of acid-suppressant therapy on clinicopathologic parameters of cats with chronic kidney disease}, volume={20}, DOI={10.1177/1098612x17718132}, abstractNote={Objectives The aim was to retrospectively evaluate the effects of acid-suppressant therapy in a population of cats with chronic kidney disease (CKD). The study objectives were to evaluate the effects of acid-suppressant therapy on clinicopathologic variables and progression of CKD over time. }, number={6}, journal={Journal of Feline Medicine and Surgery}, author={Gould, E. and Klos, J. and Price, J. and Harris, T. and Vaden, S. and Tolbert, M. K.}, year={2018}, pages={520–527} }
 @article{florey_viall_streu_dimuro_riddle_kirk_perazzotti_affeldt_wagner_vaden_et al._2017, title={Use of a Granulocyte Immunofluorescence Assay Designed for Humans for Detection of Antineutrophil Cytoplasmic Antibodies in Dogs with Chronic Enteropathies}, volume={31}, ISSN={["1939-1676"]}, DOI={10.1111/jvim.14774}, abstractNote={BackgroundPerinuclear antineutrophil cytoplasmic antibodies (pANCA) previously have been shown to be serum markers in dogs with chronic enteropathies, with dogs that have food‐responsive disease (FRD) having higher frequencies of seropositivity than dogs with steroid‐responsive disease (SRD). The indirect immunofluorescence (IIF) assay used in previous publications is time‐consuming to perform, with low interobserver agreement.}, number={4}, journal={JOURNAL OF VETERINARY INTERNAL MEDICINE}, author={Florey, J. and Viall, A. and Streu, S. and DiMuro, V. and Riddle, A. and Kirk, J. and Perazzotti, L. and Affeldt, K. and Wagner, R. and Vaden, S. and et al.}, year={2017}, pages={1062–1066} }
 @article{olby_vaden_williams_griffith_harris_mariani_muñana_early_platt_boozer_et al._2016, title={Effect of Cranberry Extract on the Frequency of Bacteriuria in Dogs with Acute Thoracolumbar Disk Herniation: A Randomized Controlled Clinical Trial}, volume={31}, ISSN={0891-6640}, url={http://dx.doi.org/10.1111/jvim.14613}, DOI={10.1111/jvim.14613}, abstractNote={BackgroundDogs with spinal cord injury are at increased risk of developing bacteriuria due to increased residual urine volume. Cranberry extract inhibits binding of E. coli to uroepithelial cells, potentially reducing risk of bacteriuria.}, number={1}, journal={Journal of Veterinary Internal Medicine}, publisher={Wiley}, author={Olby, N.J. and Vaden, S.L. and Williams, K. and Griffith, E.H. and Harris, T. and Mariani, C.L. and Muñana, K.R. and Early, P.J. and Platt, S.R. and Boozer, L. and et al.}, year={2016}, month={Dec}, pages={60–68} }
 @article{rousse_olby_williams_harris_griffith_mariani_muñana_early_2016, title={Recovery of stepping and coordination in dogs following acute thoracolumbar intervertebral disc herniations}, volume={213}, ISSN={1090-0233}, url={http://dx.doi.org/10.1016/j.tvjl.2016.04.002}, DOI={10.1016/j.tvjl.2016.04.002}, abstractNote={Prospective data on the recovery of coordination in dogs suffering acute thoracolumbar intervertebral disc herniations (TL-IVDH) are limited. The purpose of this study was to use treadmill based and open field scores (OFS) to quantify recovery of stepping ability and forelimb, hindlimb coordination in the 6 weeks following surgical decompression of dogs with TL-IVDH. Sixty-three dogs were grouped at presentation as grades 3 (non-ambulatory paraparetic), 4 (paraplegic) or 5 (paraplegic without pain sensation) and were evaluated 2, 4, and 6 weeks post-operatively. Stepping scores and Regularity Index (RI), a measure of coordination, were calculated from treadmill walking, and an OFS incorporating supported and unsupported walking was assigned. Outcomes for the three measures were compared between groups and correlation between scoring methods was assessed. Grade 3 and 4 dogs recovered ambulation by 2 weeks, reaching median stepping scores of 96 and 90% by 6 weeks, respectively. Recovery of coordination differed between groups 3 and 4 with median RI scores of 93.9% and 63%, respectively, by 6 weeks. Eight grade 5 dogs failed to recover independent ambulation by 6 weeks. Nine dogs recovered with scores that were significantly worse than the grade 3 and 4 dogs at 6 weeks for stepping score (P < 0.001) and RI (P < 0.001). OFS correlated closely with stepping and RI scores and each group was significantly different using this ordinal scale. In conclusion, recovery of coordination was incomplete in dogs that showed good recovery of stepping. The data generated could be used for clinical trial design.}, journal={The Veterinary Journal}, publisher={Elsevier BV}, author={Rousse, C.A. and Olby, N.J. and Williams, K. and Harris, T.L. and Griffith, E.H. and Mariani, C.L. and Muñana, K.R. and Early, P.J.}, year={2016}, month={Jul}, pages={59–63} }
 @article{agler_nielsen_urkasemsin_singleton_tonomura_sigurdsson_tang_linder_arepalli_hernandez_et al._2014, title={Canine hereditary ataxia in Old English Sheepdogs and Gordon Setters is associated with a defect in the autophagy gene encoding RAB24}, volume={10}, number={2}, journal={PLoS Genetics}, author={Agler, C. and Nielsen, D. M. and Urkasemsin, G. and Singleton, A. and Tonomura, N. and Sigurdsson, S. and Tang, R. Q. and Linder, K. and Arepalli, S. and Hernandez, D. and et al.}, year={2014} }
 @article{olby_lim_babb_bach_domaracki_williams_griffith_harris_muguet-chanoit_2014, title={Gait scoring in dogs with thoracolumbar spinal cord injuries when walking on a treadmill}, volume={10}, journal={BMC Veterinary Research}, author={Olby, N. J. and Lim, J. H. and Babb, K. and Bach, K. and Domaracki, C. and Williams, K. and Griffith, E. and Harris, T. and Muguet-Chanoit, A.}, year={2014} }
 @article{hutchins_vaden_jacob_harris_bowles_wood_bailey_2014, title={Vaginal Microbiota of Spayed Dogs with or without Recurrent Urinary Tract Infections}, volume={28}, ISSN={["1939-1676"]}, DOI={10.1111/jvim.12299}, abstractNote={BackgroundLimited information is available regarding the vaginal microbiota of normal spayed dogs and spayed dogs with recurrent UTIs. Vaginal lactic acid‐producing bacteria (LAB) have been associated with decreased frequency of recurrent urinary tract infection in women and may have a protective role within the urinary tract of female dogs.}, number={2}, journal={JOURNAL OF VETERINARY INTERNAL MEDICINE}, author={Hutchins, R. G. and Vaden, S. L. and Jacob, M. E. and Harris, T. L. and Bowles, K. D. and Wood, M. W. and Bailey, C. S.}, year={2014}, month={Mar}, pages={300–304} }
 @article{hutchins_bailey_jacob_harris_wood_saker_vaden_2013, title={The Effect of an Oral Probiotic Containing Lactobacillus, Bifidobacterium, and Bacillus Species on the Vaginal Microbiota of Spayed Female Dogs}, volume={27}, ISSN={["1939-1676"]}, DOI={10.1111/jvim.12174}, abstractNote={BackgroundRecurrent urinary tract infections (UTIs) are often difficult to treat. Vaginal colonization with lactic acid‐producing bacteria (LAB) is associated with reduced frequency of recurrent UTIs in women. Oral probiotics might help increase the prevalence of vaginal LAB and decrease the frequency of recurrent UTIs in dogs.}, number={6}, journal={JOURNAL OF VETERINARY INTERNAL MEDICINE}, author={Hutchins, R. G. and Bailey, C. S. and Jacob, M. E. and Harris, T. L. and Wood, M. W. and Saker, K. E. and Vaden, S. L.}, year={2013}, month={Nov}, pages={1368–1371} }
 @article{klosterman_moore_galvao_dibartola_groman_whittemore_vaden_harris_byron_dowling_et al._2011, title={Comparison of Signalment, Clinicopathologic Findings, Histologic Diagnosis, and Prognosis in Dogs with Glomerular Disease with or without Nephrotic Syndrome}, volume={25}, ISSN={["1939-1676"]}, DOI={10.1111/j.1939-1676.2010.0669.x}, abstractNote={Background:  Nephrotic syndrome (NS) develops most commonly in people with glomerular diseases associated with marked albuminuria. Hypernatremia, hypertension, and progressive renal failure are more prevalent in nephrotic than nonnephrotic human patients.}, number={2}, journal={JOURNAL OF VETERINARY INTERNAL MEDICINE}, author={Klosterman, E. S. and Moore, G. E. and Galvao, J. F. de Brito and DiBartola, S. P. and Groman, R. P. and Whittemore, J. C. and Vaden, S. L. and Harris, T. L. and Byron, J. K. and Dowling, S. R. and et al.}, year={2011}, pages={206–214} }
 @article{vaden_turman_harris_marks_2010, title={The prevalence of albuminuria in dogs and cats in an ICU or recovering from anesthesia}, volume={20}, ISSN={["1476-4431"]}, DOI={10.1111/j.1476-4431.2010.00584.x}, abstractNote={Abstract}, number={5}, journal={JOURNAL OF VETERINARY EMERGENCY AND CRITICAL CARE}, author={Vaden, Shelly L. and Turman, Coral A. and Harris, Tonya L. and Marks, Steven L.}, year={2010}, month={Oct}, pages={479–487} }
 @article{levine_zhang_harris_vaden_2010, title={The use of pooled vs serial urine samples to measure urine protein:creatinine ratios}, volume={39}, ISSN={["0275-6382"]}, DOI={10.1111/j.1939-165x.2009.00167.x}, abstractNote={Background:  Evaluation of serial urine protein:creatinine (UPC) ratios is important in prognosticating chronic kidney disease and monitoring response to therapeutic interventions. Owing to random biologic variation in dogs with stable glomerular proteinuria, multiple determinations of UPC ratios often are recommended to reliably assess urine protein loss. This can be cost‐prohibitive.}, number={1}, journal={VETERINARY CLINICAL PATHOLOGY}, author={LeVine, Dana N. and Zhang, Daowen and Harris, Tonya and Vaden, Shelly L.}, year={2010}, month={Mar}, pages={53–56} }
 @article{allenspach_lomas_wieland_harris_pressler_mancho_lees_vaden_2008, title={Evaluation of perinuclear anti-neutrophilic cytoplasmic autoantibodies as an early marker of protein-losing enteropathy and protein-losing nephropathy in Soft Coated Wheaten Terriers}, volume={69}, ISSN={["1943-5681"]}, DOI={10.2460/ajvr.69.10.1301}, abstractNote={Abstract}, number={10}, journal={AMERICAN JOURNAL OF VETERINARY RESEARCH}, author={Allenspach, Karin and Lomas, Bethany and Wieland, Barbara and Harris, Tonya and Pressler, Barrak and Mancho, Carolina and Lees, George E. and Vaden, Shelly L.}, year={2008}, month={Oct}, pages={1301–1304} }
 @article{olby_harris_burr_munana_sharp_keene_2004, title={Recovery of pelvic limb function in dogs following acute intervertebral disc herniations}, volume={21}, ISSN={["1557-9042"]}, url={http://www.scopus.com/inward/record.url?eid=2-s2.0-0942290535&partnerID=MN8TOARS}, DOI={10.1089/089771504772695940}, abstractNote={Chondrodystrophoid breeds of dog are prone to explosive herniation of mineralized disc material into the thoracolumbar spinal canal. The resulting acute spinal cord injury may represent an excellent spontaneous model of acute traumatic spinal cord injury. The aims of this study were to quantify the recovery of dogs following acute disc herniations, to evaluate external factors that influence recovery, and to identify a group of dogs suitable for use in clinical trials on neuroprotective drugs. The gait of 88 dogs with thoracolumbar disc herniations was scored at the time of injury and 2, 4, and 12 weeks after surgical decompression. Dogs were placed into four groups dependent on the severity of presenting signs; dogs in group 1 had the most severe injury severity. Group 1 dogs showed a variable but incomplete recovery by 12 weeks. Dogs in groups 2 and 3 recovered uniformly but more completely, while dogs in group 4 made a rapid and excellent recovery and were deemed unsuitable for clinical trials. Combining dogs in groups 1, 2 and 3 produced a population of dogs with incomplete recovery by 12 weeks. Power analysis revealed that 87 such dogs would be needed per treatment group to detect a 20% change in function with a power of 95%. The number needed reduced drastically to 19 by eliminating dogs in group 1, but this produced less room for functional improvement. External factors did not appear to influence outcome. We conclude that dogs with spontaneous disc herniations provide a useful model of acute spinal cord injury for clinical trials.}, number={1}, journal={JOURNAL OF NEUROTRAUMA}, author={Olby, N and Harris, T and Burr, J and Munana, K and Sharp, N and Keene, B}, year={2004}, month={Jan}, pages={49–59} }
 @article{olby_levine_harris_muñana_skeen_sharp_2003, title={Long-term functional outcome of dogs with severe injuries of the thoracolumbar spinal cord: 87 cases (1996–2001)}, volume={222}, ISSN={0003-1488}, url={http://dx.doi.org/10.2460/javma.2003.222.762}, DOI={10.2460/javma.2003.222.762}, abstractNote={Abstract}, number={6}, journal={Journal of the American Veterinary Medical Association}, publisher={American Veterinary Medical Association (AVMA)}, author={Olby, Natasha and Levine, Jay and Harris, Tonya and Muñana, Karen and Skeen, Todd and Sharp, Nick}, year={2003}, month={Mar}, pages={762–769} }