@article{stonex_watanabe_robertson_westermeyer_2023, title={Equine pectinate ligament descemetization is associated with age}, volume={2}, ISSN={["1463-5224"]}, DOI={10.1111/vop.13071}, abstractNote={AbstractPurposeTo evaluate the correlation between equine pectinate ligament descemetization and ocular disease.MethodsThe pathology database of the North Carolina State University Veterinary Medical Center was searched from 2010–2021 for all equine globes. Disease status was then assigned as affected by glaucoma, uveitis, or “other” based upon clinical records. The iridocorneal angles (ICA) of each globe were evaluated for the presence of pectinate ligament descemetization, the length of descemetization, as well as for the degree of angle collapse and the extent of cellular infiltrate or proteinaceous debris. One slide from each eye was evaluated by two separate, blinded investigators (HW & TS).ResultsA total of 66 eyes from 61 horses were identified, with a total of 124 sections of ICA of sufficient quality to review. 16 horses were affected by uveitis, 8 by glaucoma, 7 by both glaucoma and uveitis, and 30 horses by other ocular disease, most commonly ocular surface disease or neoplasia, which served as controls. Pectinate ligament descemetization was most prevalent in the control group compared to the glaucoma and uveitis groups. Pectinate ligament descemetization length was positively correlated with age, with an increase of 13.5 μm per year of age (p = .016). Infiltrate scores and angle closure scores were higher in both the glaucoma and uveitis group compared to the control group (p < .001).ConclusionsEquine pectinate ligament descemetization appears to be correlated with increased age and should not be used as a histologic marker for the presence of glaucoma.}, journal={VETERINARY OPHTHALMOLOGY}, author={Stonex, Tara M. and Watanabe, Tatiane Terumi Negrao and Robertson, James B. and Westermeyer, Hans D.}, year={2023}, month={Feb} }
 @article{stonex_zibura_andres_gilger_oh_2022, title={Polidocanol monotherapy for a superficial orbital venous malformation in a horse}, volume={25}, ISSN={1463-5216 1463-5224}, url={http://dx.doi.org/10.1111/vop.12997}, DOI={10.1111/vop.12997}, abstractNote={AbstractObjectiveTo describe the use of 1% polidocanol as the sole treatment for a superficial orbital venous malformation in a horse.AnimalA 23‐year‐old Welsh Cobb cross gelding with a distensible swelling affecting the left lower eyelid, and secondary palpebral margin abnormalities and superficial keratitis.ProcedureColor flow Doppler ultrasonography revealed non‐pulsatile blood flow within the tortuous vascular network most consistent with a superficial orbital venous malformation appearing to involve the lateral palpebral and transverse facial veins. An intravenous catheter was placed within the lateral aspect of the venous malformation, and agitated saline was slowly injected into the vessel while simultaneously ultrasound imaging the medial aspect in which the bubbles were observed coursing across, consistent with lateral to medial flow. Contrast venography confirmed a corkscrew vessel along the ventral aspect of the orbital rim. Under standing sedation, 1% polidocanol solution was administered slowly through the intravenous catheter while manual pressure was applied on the medial and lateral aspects of the venous malformation.ResultsUltrasonography performed immediately after administration of polidocanol confirmed venous stasis, and formation of a thrombus. No adverse side effects were noted. The venous malformation and associated palpebral margin abnormalities and superficial keratitis resolved at the time of re‐examination at 4 months.Conclusion and Clinical RelevancePolidocanol as the sole treatment for a superficial orbital venous malformation in a horse was well tolerated and led to clinical resolution. Sclerosant monotherapy may be a safe treatment option for superficial orbital venous malformations.}, number={5}, journal={Veterinary Ophthalmology}, publisher={Wiley}, author={Stonex, Tara M. and Zibura, Ashley E. and Andres, Michael and Gilger, Brian C. and Oh, Annie}, year={2022}, month={Jun}, pages={412–418} }