Tyler Ash

College of Engineering

Works (1)

Updated: July 5th, 2023 14:24

2020 article

Abstract 408: An Essential Protective Role for Cardiomyocyte Alpha1a-adrenergic Receptors in a Mouse Model of Myocardial Infarction

Zhang, J., Ash, T., Huang, W., Smith, A., Huang, H.-ying, & Jensen, B. C. (2020, July 31). Circulation Research.

By: J. Zhang *, T. Ash n, W. Huang *, A. Smith*, H. Huang n  & B. Jensen *

topics (OpenAlex): Receptor Mechanisms and Signaling; Nitric Oxide and Endothelin Effects; Neuropeptides and Animal Physiology
TL;DR: It is demonstrated that mice deficient of α1A-AR on cardiomyocytes had lower late survival, more profound early pathological injury & adverse mechanical properties after LAD ligation, suggesting that activation ofCardiomyocyte β-ARs plays an essential role in protecting experimental myocadiac infarction, holds the promise of future clinical implications. (via Semantic Scholar)
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