Tyler Ash

College of Engineering

2020 article

An Essential Protective Role for Cardiomyocyte Alpha1a-adrenergic Receptors in a Mouse Model of Myocardial Infarction

Zhang, J., Ash, T., Huang, W., Smith, A., Huang, H.-Y., & Jensen, B. C. (2020, July 31). CIRCULATION RESEARCH, Vol. 127.

By: J. Zhang*, T. Ash*, W. Huang*, A. Smith*, H. Huang n & B. Jensen*

TL;DR: It is demonstrated that mice deficient of α1A-AR on cardiomyocytes had lower late survival, more profound early pathological injury & adverse mechanical properties after LAD ligation, suggesting that activation ofCardiomyocyte β-ARs plays an essential role in protecting experimental myocadiac infarction, holds the promise of future clinical implications. (via Semantic Scholar)
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