Works (448)

Updated: May 8th, 2024 05:21

2024 article

Figurate erythema in 11 Eastern European sphynx cats

Mendoza-Kuznetsova, E., Lokianskiene, V., Matise-VanHoutan, I., Fiskovich, O., & Olivry, T. (2024, January 29). VETERINARY DERMATOLOGY, Vol. 1.

By: E. Mendoza-Kuznetsova*, V. Lokianskiene, I. Matise-VanHoutan, O. Fiskovich & T. Olivry n

author keywords: annular erythema; feline; figurate erythema; sphynx cat
TL;DR: The clinical remission of FE was not achieved with diet changes or medical interventions; yet, a spontaneous, transient, partial or complete improvement occurred in most cats. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: February 1, 2024

2023 article

Cytokine transcriptome profiling in acute experimental canine atopic dermatitis skin lesions after IL-31 inhibition with lokivetmab

Tamamoto-Mochizuki, C., Crawford, N., Eder, J. M., Gonzales, A. J., & Olivry, T. (2023, April 2). VETERINARY DERMATOLOGY, Vol. 4.

author keywords: atopic dermatitis; cytokines; dog; IL-31 inhibition
TL;DR: IL-31 inhibition is insufficient to prevent the expression of other proinflammatory mediators in acute AD and these could be considered as other potential therapeutic targets. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: April 3, 2023

2023 journal article

Effective treatment of canine chronic cutaneous lupus erythematosus variants with oclacitinib: Seven cases

Veterinary Dermatology.

By: R. Harvey*, A. Olivrī, T. Lima* & T. Olivry*

MeSH headings : Dogs; Animals; Lupus Erythematosus, Discoid / drug therapy; Lupus Erythematosus, Discoid / veterinary; Lupus Erythematosus, Cutaneous / drug therapy; Lupus Erythematosus, Cutaneous / veterinary; Lupus Erythematosus, Cutaneous / diagnosis; Pyrimidines; Sulfonamides; Dog Diseases / diagnosis
TL;DR: Oclacitinib may be considered an effective treatment option for different variants of canine CCLE variants due to their rapid inhibition of the action of interferons known to be relevant in the pathogenesis of CCLE. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: ORCID
Added: October 14, 2022

2023 article

Histopathological characterisation of trunk-dominant canine pemphigus foliaceus, and comparison with classic facial and insecticide-triggered forms

Gedon, N. K. Y., Bizikova, P., Olivry, T., Mendoza-Kuznetsova, E., Oberkirchner, U., Robertson, J. B., & Linder, K. E. (2023, June 14). VETERINARY DERMATOLOGY, Vol. 6.

By: N. Gedon n, P. Bizikova n, T. Olivry n, E. Mendoza-Kuznetsova*, U. Oberkirchner*, J. Robertson n, K. Linder n

author keywords: acantholysis; autoimmune diseases; dog diseases; pathological findings; pemphigus; skin diseases
TL;DR: Trunk-dominant PF and other canine PF variants are histologically similar, which indicates shared pathomechanisms, and results indicate that diagnostic biopsies cannot differentiate between these PF variants in dogs. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: July 3, 2023

2023 review

Spontaneous autoimmune subepidermal blistering diseases in animals: a comprehensive review

[Review of ]. BMC VETERINARY RESEARCH, 19(1).

By: P. Bizikova n, T. Olivry n, K. Linder n & J. Rybnicek

author keywords: Autoimmune; Skin; Pemphigoid; Dog; Cat; Blister
MeSH headings : Humans; Animals; Dogs; Skin; Pemphigus / veterinary; Epidermis; Autoantibodies; Breeding; Dog Diseases / diagnosis
TL;DR: Canine AISBDs are the best characterised, particularly the more common variants such as mucous membrane pemphigoid (48%), epidermolysis bullosa acquisita (EBA) (26%), and bullous pem PHD (10%), and shorter descriptions of variants in other species are provided. (via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land (OpenAlex)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: February 27, 2023

2022 journal article

A Pilot Randomized Trial to Compare Polyuria and Polydipsia during a Short Course of Prednisolone or Methylprednisolone in Dogs with Atopic Dermatitis

VETERINARY SCIENCES, 9(9).

By: V. Lokianskiene, K. Bergvall* & T. Olivry n

author keywords: atopic dermatitis; dog; methylprednisolone; prednisolone; polyuria-polydipsia
TL;DR: The administration of two weeks of oral prednisolone and methylprednisol one at equipotent anti-inflammatory dosages at the beginning of an elimination diet did not lead to significant differences in water intake and USG, and there was no significant difference between the two steroids for urine dilution. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: September 14, 2022

2022 article

A randomised controlled trial testing the rebound-preventing benefit of four days of prednisolone during the induction of oclacitinib therapy in dogs with atopic dermatitis

Olivry, T., Lokianskiene, V., Blanco, A., Del Mestre, P., Bergvall, K., & Beco, L. (2022, November 4). VETERINARY DERMATOLOGY, Vol. 11.

By: T. Olivry n, V. Lokianskiene, A. Blanco, P. Del Mestre, K. Bergvall* & L. Beco

MeSH headings : Dogs; Animals; Dermatitis, Atopic / drug therapy; Dermatitis, Atopic / veterinary; Dermatitis, Atopic / complications; Prednisolone / therapeutic use; Dermatologic Agents; Pruritus / veterinary; Dog Diseases / pathology; Immunoglobulin A / therapeutic use
TL;DR: The initial addition of 4 days of prednisolone significantly decreased the probability of a rebound of pruritus 1 week after oclacitinib dose reduction, and this short concomitant glucocorticoid administration led to a higher skin lesion improvement and improved perception of treatment efficacy with minimal adverse effects. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: November 5, 2022

2022 journal article

Bayesian model and selection signature analyses reveal risk factors for canine atopic dermatitis

COMMUNICATIONS BIOLOGY, 5(1).

MeSH headings : Animals; Dogs / genetics; Bayes Theorem; Dermatitis, Atopic / genetics; Dermatitis, Atopic / veterinary; Risk Factors
TL;DR: A Bayesian mixture model adapted for mapping complex traits and a cross-population extended haplotype test is applied to search for disease-associated loci and selective sweeps in four dog breeds at risk for atopic dermatitis and identifies candidate genes, including genes belonging to the same biological pathways across multiple loci, with potential relevance to the pathogenesis of canine atopy dermatitis. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: February 19, 2023

2022 article

Evaluation of native canine skin color by smartphone-based dermatoscopy

Cugmas, B., Struc, E., Kovce, U., Luzar, K., & Olivry, T. (2022, January 22). SKIN RESEARCH AND TECHNOLOGY, Vol. 1.

By: B. Cugmas*, E. Struc, U. Kovce, K. Luzar & T. Olivry n

author keywords: canine skin; carotenoids; CIELAB color space; ColorChecker; dermatoscopy; dogs; erythema; skin color; skin colorimetry; veterinary dermatology
MeSH headings : Animals; Color; Colorimetry / methods; Dermoscopy; Dogs; Erythema; Humans; Skin / diagnostic imaging; Skin Pigmentation; Smartphone
TL;DR: Human skin color, predominantly determined by the chromophores of melanin, hemoglobin, and exogenous carotenoids, is often measured to serve various medical and cosmetic applications. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: January 31, 2022

2022 article

Evaluation of the theoretical risk of cross-reactivity among recently identified food allergens for dogs

Olivry, T., O'Malley, A., & Chruszcz, M. (2022, August 31). VETERINARY DERMATOLOGY, Vol. 8.

By: T. Olivry n, A. O'Malley* & M. Chruszcz*

MeSH headings : Animals; Dogs; Allergens; Cross Reactions; Dog Diseases / immunology; Food Hypersensitivity / veterinary; Immunoglobulin E
TL;DR: The A‐RISC indices suggest a substantial theoretical risk of cross‐reactivity between species for all allergens considered and for TPM, this risk also extends to the environmental and nematode allergens. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: ORCID, Web Of Science, NC State University Libraries
Added: September 1, 2022

2022 article

Hyperkeratotic erythema multiforme variant in 17 dogs

Banovic, F., Olivry, T., Artlet, B., Rothstein, E., Beco, L., Linek, M., … Linder, K. (2022, December 12). VETERINARY DERMATOLOGY, Vol. 12.

By: F. Banovic*, T. Olivry n, B. Artlet*, E. Rothstein, L. Beco, M. Linek, S. Zabel, J. Peters-Kennedy* ...

author keywords: dog; erythema multiforme; hyperkeratotic
MeSH headings : Male; Dogs; Animals; Parakeratosis / pathology; Parakeratosis / veterinary; Dog Diseases / diagnosis; Erythema Multiforme / drug therapy; Erythema Multiforme / veterinary; Erythema Multiforme / diagnosis; Skin / pathology; Epidermis / pathology
TL;DR: Hyperkeratotic ery thema multiforme (HKEM) is a chronic, persistent and clinically distinctive erythema multangulare (EM) variant that differs from 'classic' vesiculobullous erosive-to-ulcerative EM in dogs. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: ORCID, Web Of Science, NC State University Libraries
Added: December 13, 2022

2022 article

What can we learn from treating atopic itch in dogs?

Labib, A., Yosipovitch, G., & Olivry, T. (2022, August). JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, Vol. 150, pp. 284–286.

By: A. Labib*, G. Yosipovitch* & T. Olivry n

author keywords: Atopic dermatitis; eczema; dog; pruritus; itch; JAK inhibitor; IL-31 inhibitor; oclacitinib; lokivetmab
MeSH headings : Animals; Dermatitis, Atopic / therapy; Dogs; Pruritus / therapy
Sources: Web Of Science, NC State University Libraries
Added: December 5, 2022

2021 article

An international seroprevalence survey of the IgE sensitisation to the Dermatophagoides farinae house dust mite and two of its major allergens (Der f 2, Zen 1) in atopic dogs

Favrot, C., Olivry, T., & Iwasaki, T. (2021, August 19). VETERINARY DERMATOLOGY, Vol. 33.

By: C. Favrot*, T. Olivry n & T. Iwasaki*

MeSH headings : Allergens; Animals; Antigens, Dermatophagoides; Arthropod Proteins; Dermatitis, Atopic / immunology; Dermatitis, Atopic / veterinary; Dermatophagoides farinae; Dog Diseases / epidemiology; Dog Diseases / immunology; Dogs; Immunoglobulin E; Mites; Seroepidemiologic Studies
TL;DR: There was significant correlation between the IgE levels to these three allergens which was highest between Df and Zen 1, and lowest between Zen 1 and Der f 2, which indicates that IgE sensitisation to Df is geographically widespread. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: ORCID, Web Of Science, NC State University Libraries
Added: August 20, 2021

2021 article

Determination of the efficacy rate and time-to-efficacy of subcutaneous immunotherapy in dogs with atopic dermatitis

Tham, H. L., & Olivry, T. (2021, December 9). VETERINARY DERMATOLOGY, Vol. 33.

By: H. Tham* & T. Olivry n

MeSH headings : Allergens; Animals; Dermatitis, Atopic / drug therapy; Dermatitis, Atopic / veterinary; Desensitization, Immunologic / methods; Desensitization, Immunologic / veterinary; Dog Diseases / drug therapy; Dogs; Immunotherapy / methods; Immunotherapy / veterinary; Injections, Subcutaneous / veterinary; Pruritus / veterinary
TL;DR: Novel SCIT regimens appear to have a faster - and possibly higher - efficacy than the currently available aqueous or alum-precipitated formulations. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: ORCID, Web Of Science, NC State University Libraries
Added: December 10, 2021

2021 journal article

Evaluation of Erythema Severity in Dermatoscopic Images of Canine Skin: Erythema Index Assessment and Image Sampling Reliability

SENSORS, 21(4).

By: B. Cugmas*, D. Viskere*, E. Struc & T. Olivry n

author keywords: canine atopic dermatitis; smartphone dermatoscopy; erythema severity; erythema index; dogs; disease severity scales; CADESI4; intraclass correlation coefficient; multispectral imaging; image sampling
MeSH headings : Animals; Dog Diseases / diagnostic imaging; Dogs; Erythema / diagnostic imaging; Erythema / veterinary; Image Interpretation, Computer-Assisted; Reproducibility of Results; Severity of Illness Index; Skin / diagnostic imaging; Specimen Handling
TL;DR: The results indicated that smartphone-based dermatoscopy could be a convenient and precise way to evaluate skin erythema severity, however, better outlined, or even automated ISMs are likely to improve the intra- and inter-rater reliability in severe ery thematous cases. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: March 22, 2021

2021 journal article

Evaluation of Plasma C-Reactive Protein as a Biomarker in Dogs with Atopic Dermatitis Receiving Allergen-Specific Immunotherapy: A Pilot Study

SCHWEIZER ARCHIV FUR TIERHEILKUNDE, 163(1), 67–72.

author keywords: atopic dermatitis; biomarker; CRP; dog
MeSH headings : Animals; Biomarkers / blood; C-Reactive Protein / analysis; Dermatitis, Atopic / blood; Dermatitis, Atopic / pathology; Dermatitis, Atopic / therapy; Dermatitis, Atopic / veterinary; Desensitization, Immunologic / veterinary; Dog Diseases / blood; Dog Diseases / diagnosis; Dog Diseases / therapy; Dogs; Pilot Projects; Plasma / chemistry
TL;DR: The lack of significant difference in CRP levels between dogs of increasing AD severity and lack of correlation between percentage changes in skin lesion and CRP values suggest that this protein would not be a clinically-useful biomarker in atopic dogs. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: February 8, 2021

2021 journal article

Evaluation of skin erythema severity by dermatoscopy in dogs with atopic dermatitis

VETERINARY DERMATOLOGY, 32(2), 183-+.

By: B. Cugmas* & T. Olivry n

MeSH headings : Animals; Dermatitis, Atopic / veterinary; Dermoscopy / veterinary; Dog Diseases / diagnosis; Dogs; Erythema / veterinary; Severity of Illness Index
TL;DR: The proposed optical set-up with a smartphone and a dermatoscope has the potential to make erythema severity estimation objective, thus leading to more reliable AD severity scales for the use in experimental canine AD models or in clinical trials enrolling atopic dogs. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: January 8, 2021

2021 journal article

Feline allergic diseases: introduction and proposed nomenclature

VETERINARY DERMATOLOGY, 32(1), 8-+.

By: R. Halliwell*, C. Pucheu-Haston*, T. Olivry n, C. Prost*, H. Jackson, F. Banovic*, T. Nuttall*, D. Santoro*, P. Bizikova n, R. Mueller*

MeSH headings : Allergens; Animals; Cat Diseases / classification; Cat Diseases / immunology; Cat Diseases / pathology; Cats; Dermatitis, Atopic / classification; Dermatitis, Atopic / immunology; Dermatitis, Atopic / pathology; Dermatitis, Atopic / veterinary; Dogs; Food Hypersensitivity / veterinary; Humans; Skin / pathology; Terminology as Topic
UN Sustainable Development Goal Categories
Sources: ORCID, Web Of Science, NC State University Libraries
Added: January 20, 2021

2021 review

IL-31 and IL-31 receptor expression in acute experimental canine atopic dermatitis skin lesions

[Review of ]. VETERINARY DERMATOLOGY, 32(6), 631-+.

By: C. Tamamoto-Mochizuki n & T. Olivry n

MeSH headings : Animals; Dermatitis, Atopic / veterinary; Dog Diseases; Dogs; Interleukins; Keratinocytes; Skin
TL;DR: The early and transient production of IL-31 by Th cells supports the concept of usingIL-31 inhibiting strategies as a proactive therapy to prevent flares of AD skin lesions. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: ORCID, Web Of Science, NC State University Libraries
Added: November 19, 2021

2021 article

Identification of major and minor chicken allergens in dogs

Olivry, T., Pucheu-Haston, C. M., Mayer, U., Bergvall, K., & Bexley, J. (2021, November 3). VETERINARY DERMATOLOGY, Vol. 33.

By: T. Olivry n, C. Pucheu-Haston*, U. Mayer, K. Bergvall* & J. Bexley*

MeSH headings : Allergens; Animals; Chickens; Cross Reactions; Dog Diseases; Dogs; Enzyme-Linked Immunosorbent Assay / veterinary; Hypersensitivity / veterinary; Immunoglobulin E
TL;DR: Seven major chicken allergens for dogs are identified and exhibit the theoretical potential to be cross-reactive between poultry and mammalian meats; six of these allergens already are known to beCross- reactive between chicken and fish species. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: ORCID, Web Of Science, NC State University Libraries
Added: November 4, 2021

2021 journal article

Immunopathogenesis of the feline atopic syndrome

VETERINARY DERMATOLOGY, 32(1), 13-+.

By: R. Halliwell*, F. Banovic*, R. Mueller* & T. Olivry n

MeSH headings : Allergens; Animals; Asthma / immunology; Asthma / physiopathology; Asthma / veterinary; Cat Diseases / immunology; Cat Diseases / physiopathology; Cats; Dermatitis, Atopic / immunology; Dermatitis, Atopic / physiopathology; Dermatitis, Atopic / veterinary; Hypersensitivity / veterinary; Hypersensitivity, Immediate / veterinary; Immune System Diseases / physiopathology; Immune System Diseases / veterinary; Immunoglobulin E / immunology; Syndrome
TL;DR: The evidence reviewed was supportive of a role for immunoglobulin (Ig)E in the pathogenesis of both feline atopic skin syndrome (FASS) and asthma, albeit not strongly so. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: January 20, 2021

2021 article

Letter regarding "Successful nutritional control of scratching and clinical signs associated with adverse food reaction: A randomized controlled COSCAD'18 adherent clinical trial in dogs in the United States" and "Successful nutritional control of scratching and clinical signs associated with adverse food reaction: A randomized controlled COSCAD'18 adherent clinical trial in dogs in the United Kingdom" About misappropriating the COSCAD'18 for an unintended use

Olivry, T., Saridomichelakis, M., & Santoro, D. (2021, October 25). JOURNAL OF VETERINARY INTERNAL MEDICINE, Vol. 10.

By: T. Olivry n, M. Saridomichelakis* & D. Santoro*

MeSH headings : Allergens; Animals; Dog Diseases / prevention & control; Dogs; Pruritus / veterinary; United Kingdom; United States
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: November 8, 2021

2021 article

On the possible role of food allergy in chronic urticaria in racing horses

Favrot, C., & Olivry, T. (2021, July 19). VETERINARY DERMATOLOGY, Vol. 33.

By: C. Favrot* & T. Olivry n

MeSH headings : Animals; Chronic Urticaria / veterinary; Food Hypersensitivity / veterinary; Horse Diseases / etiology; Horses; Urticaria / etiology; Urticaria / veterinary
UN Sustainable Development Goal Categories
Sources: ORCID, Web Of Science, NC State University Libraries
Added: July 20, 2021

2021 review

Periostin, an Emerging Player in Itch Sensation

[Review of ]. JOURNAL OF INVESTIGATIVE DERMATOLOGY, 141(10), 2338–2343.

By: T. Hashimoto*, S. Mishra n, T. Olivry n & G. Yosipovitch*

MeSH headings : Animals; Cell Adhesion Molecules / physiology; Humans; Integrins / physiology; Natriuretic Peptide, Brain / physiology; Pruritus / etiology; Sensation; TRPA1 Cation Channel / physiology
TL;DR: The role of periostin in itch induction in human and animal models and its expression in human pruritic conditions are described. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: May 21, 2021

2021 article

Transient and reversible reduction of stratum corneum filaggrin degradation products after allergen challenge in experimentally mite-sensitised atopic dogs

Olivry, T., Paps, J. S., & Amalric, N. (2021, September 14). VETERINARY DERMATOLOGY, Vol. 33.

By: T. Olivry n, J. Paps n & N. Amalric

MeSH headings : Allergens; Animals; Dermatitis, Atopic / veterinary; Dog Diseases; Dogs; Epidermis; Filaggrin Proteins; Mites; Skin
TL;DR: In this experimental model, a single epicutaneous allergen challenge led to a transient and reversible decrease in skin surface NMF and its components, and concentrations were negatively correlated with skin lesion scores. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: ORCID, Web Of Science, NC State University Libraries
Added: September 15, 2021

2020 journal article

A Missense Variant Affecting the C-Terminal Tail of UNC93B1 in Dogs with Exfoliative Cutaneous Lupus Erythematosus (ECLE)

GENES, 11(2).

By: T. Leeb*, F. Leuthard*, V. Jagannathan*, S. Kiener*, A. Letko*, P. Roosje*, M. Welle*, K. Gailbreath ...

Contributors: T. Leeb*, F. Leuthard*, V. Jagannathan*, S. Kiener*, A. Letko*, P. Roosje*, M. Welle*, K. Gailbreath ...

author keywords: Canis familiaris; dermatology; immunology; animal model; skin; TLR7; toll-like receptor; syndecan binding protein; syntenin-1; systemic lupus erythematosus; SLE; CLE
MeSH headings : Animals; Dog Diseases / genetics; Dog Diseases / pathology; Dogs; Genome-Wide Association Study; Lupus Erythematosus, Cutaneous / genetics; Lupus Erythematosus, Cutaneous / pathology; Lupus Erythematosus, Cutaneous / veterinary; Male; Membrane Transport Proteins / genetics; Mutation, Missense; Whole Genome Sequencing
TL;DR: This work investigates dogs with exfoliative cutaneous lupus erythematosus (ECLE), a dog-specific form of chronic CLE that is inherited as a monogenic autosomal recessive trait and indicates that p.Pro480Thr is causing ECLE in dogs, and suggests that genetic variants affecting the C-terminus of UNC93B1 might be involved in specific subsets of CLE or SLE cases in humans and other species. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: April 6, 2020

2020 journal article

Atopic dermatitis in West Highland white terriers – part I: natural history of atopic dermatitis in the first three years of life

Veterinary Dermatology, 31(2), 106–110.

By: C. Favrot*, N. Fischer*, T. Olivry n, L. Zwickl*, S. Audergon* & A. Rostaher*

Contributors: C. Favrot*, N. Fischer*, T. Olivry n, L. Zwickl*, S. Audergon* & A. Rostaher*

TL;DR: This longitudinal study of puppies from a predisposed breed sheds new light on the early development of cAD in WHWTs. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: ORCID
Added: October 24, 2019

2020 journal article

Critically appraised topic on adverse food reactions of companion animals (9): time to flare of cutaneous signs after a dietary challenge in dogs and cats with food allergies

BMC Veterinary Research, 16(1).

By: T. Olivry n & R. Mueller*

author keywords: Food allergy; Oral food challenge; Oral provocation; Relapse
MeSH headings : Administration, Oral; Animals; Cat Diseases / diagnosis; Cat Diseases / immunology; Cats; Dermatitis / diagnosis; Dermatitis / immunology; Dermatitis / veterinary; Dog Diseases / diagnosis; Dog Diseases / immunology; Dogs; Food Hypersensitivity / diagnosis; Food Hypersensitivity / veterinary; Time Factors
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Source: ORCID
Added: May 25, 2020

2020 journal article

Deep pemphigus (pemphigus vulgaris, pemphigus vegetans and paraneoplastic pemphigus) in dogs, cats and horses: a comprehensive review

BMC Veterinary Research.

By: H. Tham*, K. Linder n & T. Olivry n

author keywords: Pemphigus; Vulgaris; Vegetans; Paraneoplastic; Desmoglein; Suprabasal; Acantholysis; Canine; Feline; Equine
MeSH headings : Animal Diseases / diagnosis; Animal Diseases / drug therapy; Animal Diseases / pathology; Animals; Cats; Dogs; Horses; Immunosuppressive Agents / therapeutic use; Pemphigus / diagnosis; Pemphigus / drug therapy; Pemphigus / pathology; Pemphigus / veterinary
TL;DR: This article will review the signalment, clinical signs, histopathology and treatment outcome of pemphigus vulgaris, pemPHigus vegetans and paraneoplastic pemPhigus in dogs, cats and horses; where pertinent, the animal diseases to their human homologue. (via Semantic Scholar)
Source: ORCID
Added: November 24, 2020

2020 journal article

Development and validation of a graphic 2D investigator’s global assessment instrument for grading the overall severity of atopic dermatitis in dogs

Veterinary Dermatology.

By: E. High n & T. Olivry n

Contributors: E. High n & T. Olivry n

MeSH headings : Animals; Dermatitis, Atopic / classification; Dermatitis, Atopic / diagnosis; Dermatitis, Atopic / veterinary; Dog Diseases / classification; Dog Diseases / diagnosis; Dogs; Equipment and Supplies / veterinary; Female; Male; Reproducibility of Results; Severity of Illness Index; Skin / pathology; Symptom Assessment / instrumentation; Symptom Assessment / veterinary
TL;DR: This novel 2D-IGA is a simple static graphic instrument that could be useful for clinical trials testing the efficacy of interventions for canine AD and shows its sensitivity to change. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: ORCID
Added: December 13, 2019

2020 journal article

LAMB3 Missense Variant in Australian Shepherd Dogs with Junctional Epidermolysis Bullosa

Genes.

By: S. Kiener*, A. Laprais*, E. Mauldin*, V. Jagannathan*, T. Olivry n & T. Leeb*

author keywords: dog; Canis lupus familiaris; whole genome sequence; wgs; dermatology; genodermatosis; skin; laminin; precision medicine
MeSH headings : Animals; Australia; Cell Adhesion Molecules / genetics; Dogs; Epidermolysis Bullosa, Junctional / genetics; Epidermolysis Bullosa, Junctional / pathology; Female; Male; Mutation, Missense; Whole Genome Sequencing
TL;DR: This study sequenced the genome of one affected puppy and compared the data to 73 control genomes, suggesting that LAMB3:c.1174T>C represents the causative variant in the JEB in domestic animals. (via Semantic Scholar)
Source: ORCID
Added: September 8, 2020

2020 journal article

Periostin Activation of Integrin Receptors on Sensory Neurons Induces Allergic Itch

CELL REPORTS, 31(1).

By: S. Mishra n, J. Wheeler n, S. Pitake n, H. Ding*, C. Jiang*, T. Fukuyama n, J. Paps n, P. Ralph n ...

Contributors: S. Mishra n, J. Wheeler n, S. Pitake n, H. Ding*, C. Jiang*, T. Fukuyama n, J. Paps n, P. Ralph n ...

MeSH headings : Animals; Cell Adhesion Molecules / metabolism; Cell Adhesion Molecules / physiology; Dermatitis, Atopic / etiology; Dermatitis, Atopic / metabolism; Dermatitis, Atopic / pathology; Dogs; Female; Hypersensitivity / physiopathology; Integrin alpha5 / metabolism; Integrin beta3 / metabolism; Integrins / metabolism; Keratinocytes / metabolism; Male; Mice; Primates; Pruritus / metabolism; Pruritus / pathology; Sensory Receptor Cells / metabolism; Skin / metabolism
TL;DR: A TSLP-periostin reciprocal activation loop that links the skin to the spinal cord via peripheral sensory neurons is identified and the non-canonical functional role of an integrin in itch is characterized. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: April 27, 2020

2020 journal article

Shortened immunotherapy dose‐escalation saves time, but is it safe? A case‐control study comparing the rates of adverse reactions between conventional and fast‐escalation subcutaneous immunotherapy protocols during the induction phase

Veterinary Dermatology.

By: I. Herrmann n, K. Loft* & T. Olivry n

MeSH headings : Allergens; Animals; Case-Control Studies; Desensitization, Immunologic / veterinary; Dogs; Injections, Subcutaneous / veterinary; Retrospective Studies
TL;DR: Despite its higher rate of AEs than with the c-SCIT regimen, the majority of f-SCit-associated AEs were mild and self-limiting, and whether or not this f- SCIT protocol leads to a faster time-to-efficacy needs to be determined. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: ORCID
Added: September 18, 2020

2020 conference paper

Skimager for the objective erythema estimation in atopic dogs

Progress in Biomedical Optics and Imaging - Proceedings of SPIE, 11211.

By: B. Cugmas*, T. Olivry n, A. Olivri & J. Spigulis*

Contributors: B. Cugmas*, T. Olivry n, A. Olivri & J. Spigulis*

author keywords: atopic dermatitis; erythema severity; erythema index; multispectral imaging; Skimager; dogs; disease severity scales; CADESI-4
TL;DR: It is concluded that optical measurements could replace the visual estimation of erythema in atopic dogs and, thus, improve the validity of skin lesion severity scales in dogs. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: ORCID
Added: April 10, 2020

2020 journal article

Transcriptional frameshifts contribute to protein allergenicity

JOURNAL OF CLINICAL INVESTIGATION, 130(10), 5477–5492.

By: B. Thouvenot, O. Roitel, J. Tomasina, B. Hilselberger, C. Richard, S. Jacquenet, F. Codreanu-Morel*, M. Morisset* ...

MeSH headings : 2S Albumins, Plant / genetics; 2S Albumins, Plant / immunology; Adolescent; Allergens / genetics; Allergens / immunology; Anaphylaxis / etiology; Anaphylaxis / immunology; Animals; Antigens, Plant / genetics; Antigens, Plant / immunology; Arachis / genetics; Arachis / immunology; Cattle; Child; Child, Preschool; Fabaceae / genetics; Fabaceae / immunology; Female; Frameshifting, Ribosomal; Genetic Variation; Humans; Immune Sera / genetics; Immune Sera / immunology; Immunoglobulin E / biosynthesis; Male; Mice; Mice, Inbred BALB C; Milk Hypersensitivity / immunology; Peanut Hypersensitivity / etiology; Peanut Hypersensitivity / immunology; Phaseolus / genetics; Phaseolus / immunology; Plant Proteins / genetics; Plant Proteins / immunology; Recombinant Proteins / genetics; Recombinant Proteins / immunology; Soybeans / genetics; Soybeans / immunology; Transcription, Genetic
TL;DR: It is proposed that it is not the canonical allergens, but their TI variants, that initiate sIgE isotype switching, while both canonical and TI variants elicit clinical allergic reactions. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: December 11, 2020

2019 journal article

Autoimmune diseases affecting skin melanocytes in dogs, cats and horses: vitiligo and the uveodermatological syndrome: a comprehensive review

BMC Veterinary Research, 15(1).

By: H. Tham*, K. Linder n & T. Olivry n

Contributors: H. Tham*, K. Linder n & T. Olivry n

author keywords: Autoimmune skin diseases; Vitiligo; Uveodermatological; Vogt-Koyanagi-Harada; Leukoderma; Depigmentation; Melanocytes; Canine; Feline; Equine; Dermatology
MeSH headings : Animal Diseases / diagnosis; Animal Diseases / etiology; Animal Diseases / therapy; Animals; Autoimmune Diseases / diagnosis; Autoimmune Diseases / therapy; Autoimmune Diseases / veterinary; Cats; Dogs; Horses; Melanocytes / pathology; Pigmentation Disorders / diagnosis; Pigmentation Disorders / etiology; Pigmentation Disorders / veterinary; Vitiligo / diagnosis; Vitiligo / etiology; Vitiligo / therapy; Vitiligo / veterinary
TL;DR: The canine uveodermatological syndrome resembles the incomplete VKH variant in humans; for affected individuals, an immediate diagnosis and aggressive treatment are crucial to prevent the development of blindness. (via Semantic Scholar)
Sources: Web Of Science, ORCID, Crossref, NC State University Libraries
Added: August 5, 2019

2019 journal article

Canine autoimmune skin diseases: selected topics

Vet Pharma, 46(1), 60–63.

By: T. Olivry

Source: NC State University Libraries
Added: September 21, 2020

2019 journal article

Critically Appraised Topic on Adverse Food Reactions of Companion Animals (8): Storage Mites in Commercial Pet foods

BMC Veterinary Research, 15(1).

By: T. Olivry n & R. Mueller*

Contributors: T. Olivry n & R. Mueller*

author keywords: Atopic dermatitis; Dermatophagoides; Dog; Food allergy; Forage mite; House dust mite; Pet food; Storage mite; Tyrophagus
MeSH headings : Animal Feed / parasitology; Animals; Dermatitis, Atopic / parasitology; Dermatitis, Atopic / veterinary; Dogs; Food Contamination; Food Storage; Mites / growth & development
TL;DR: Commercial dry pet foods should be kept indoors and sealed to decrease the risk of contamination with SM, especially Tyrophagus putrescentiae, and dietary restriction and provocation trials for the diagnosis of food allergies in dogs should be performed with single home-cooked ingredients. (via Semantic Scholar)
Source: ORCID
Added: November 1, 2019

2019 journal article

Critically appraised topic on adverse food reactions of companion animals (7): signalment and cutaneous manifestations of dogs and cats with adverse food reactions

BMC Veterinary Research, 15(1).

By: T. Olivry n & R. Mueller*

Contributors: T. Olivry n & R. Mueller*

author keywords: Allergy; Canine; Cat; Clinical signs; Dermatology; Diet; Dog; Feline; Food allergy; Skin
MeSH headings : Animals; Cats; Dogs; Food Hypersensitivity / complications; Food Hypersensitivity / epidemiology; Food Hypersensitivity / veterinary; Skin Diseases / etiology; Skin Diseases / veterinary
TL;DR: CAFRs affect dogs and cats of any age, any breed, and both genders, with the proportion of juvenile dogs diagnosed about twice that of cats, and there are no reliable breed predisposition data. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Web Of Science, ORCID, Crossref, NC State University Libraries
Added: May 28, 2019

2019 journal article

Cutaneous adverse food reactions/food allergies in dogs and cats: selected topics

Vet Pharma, 46(1), 48–51.

By: T. Olivry

Source: NC State University Libraries
Added: September 21, 2020

2019 journal article

Feline pemphigus foliaceus, a comprehensive review

Vet Pharma, 46(1), 54.

By: T. Olivry

Source: NC State University Libraries
Added: September 21, 2020

2019 journal article

Genome-wide association analysis in West Highland White Terriers with atopic dermatitis

Veterinary Immunology and Immunopathology, 209, 1–6.

By: C. Agler n, S. Friedenberg*, T. Olivry n, K. Meurs n & N. Olby n

Contributors: C. Agler n, S. Friedenberg*, T. Olivry n, K. Meurs n & N. Olby n

author keywords: Allergy; Atopic; Canine; Dogs; Genetics; GWAS; Skin
MeSH headings : Animals; Cohort Studies; Dermatitis, Atopic / genetics; Dermatitis, Atopic / veterinary; Dog Diseases / genetics; Dogs; Female; Genome-Wide Association Study / veterinary; Genotyping Techniques / veterinary; Male; Polymorphism, Single Nucleotide
TL;DR: Atopic dermatitis in WHWT is associated with a region on CFA3 that contains several candidate genes and a homozygous variant in the F2R gene present in multiple breeds that also suffer from AD warrants further evaluation. (via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land (OpenAlex)
Sources: Web Of Science, Crossref, NC State University Libraries, ORCID
Added: April 15, 2019

2019 journal article

Investigations on the expression and relevance of nerve growth factor in dogs with atopic dermatitis

Itch, 4(1), e22.

By: T. Olivry n & P. Bizikova n

TL;DR: While NGF is overexpressed in the atopic canine epidermis and after allergen challenge in sensitized dogs, the anti-NGF antibody ranevetmab did not delay pruritus flares after the discontinuation of prednisolone. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: August 29, 2019

2019 journal article

Itch-associated Neuropeptides and Their Receptor Expression in Dog Dorsal Root Ganglia and Spinal Cord

ACTA DERMATO-VENEREOLOGICA, 99(12), 1131–1135.

By: J. Wheeler*, B. Lascelles n, T. Olivry n & S. Mishra*

Contributors: J. Wheeler*, B. Lascelles n, T. Olivry n & S. Mishra*

author keywords: dog; canine atopic dermatitis; somatostatin; NPPB; NMB; GRP
MeSH headings : Animals; Calcium Signaling; Cells, Cultured; Dogs; Female; Ganglia, Spinal / metabolism; Ganglia, Spinal / physiopathology; Gene Expression Regulation; Male; Neuropeptides / genetics; Neuropeptides / metabolism; Pruritus / genetics; Pruritus / metabolism; Pruritus / physiopathology; Receptors, Neuropeptide / genetics; Receptors, Neuropeptide / metabolism; Spinal Cord / metabolism; Spinal Cord / physiopathology
TL;DR: The results provide the first evidence that dogs use similar pruritogenic pathways to those characterized in mice and thus identify multiple targets for the future treatment of itch in dogs. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: December 2, 2019

2019 journal article

Neuromedin B Induces Acute Itch in Mice via the Activation of Peripheral Sensory Neurons

Acta Dermato Venereologica, 99(6), 587–893.

By: S. Ehling n, T. Fukuyama n, M. Ko*, T. Olivry n & W. Bäumer n

Contributors: S. Ehling n, T. Fukuyama n, M. Ko*, T. Olivry n & W. Bäumer n

author keywords: acute itch; dorsal root ganglia; mast cells; neuromedin B; allergic dermatitis.
MeSH headings : Animals; Calcium / metabolism; Cell Degranulation; Cells, Cultured; Dermatitis, Allergic Contact / etiology; Female; Ganglia, Spinal / cytology; Ganglia, Spinal / metabolism; Gene Expression; Indoles / pharmacology; Injections, Intradermal; Macaca mulatta; Male; Mast Cells / metabolism; Mast Cells / physiology; Mice; Neurokinin B / administration & dosage; Neurokinin B / analogs & derivatives; Pruritus / chemically induced; Pyridines / pharmacology; RNA, Messenger / metabolism; Receptors, Bombesin / antagonists & inhibitors; Receptors, Bombesin / genetics; Receptors, Bombesin / metabolism; Sensory Receptor Cells / physiology; Single-Cell Analysis; Toluene 2,4-Diisocyanate
TL;DR: In vitro real time PCR analysis for neuromedin B and its receptor expression in murine mast cells and dorsal root ganglia as well as functional calcium imaging in the ganglia found that the peripheral signal is likely transmitted through the activation of dorsalRoot ganglia. (via Semantic Scholar)
Sources: Web Of Science, Crossref, NC State University Libraries, ORCID
Added: May 20, 2019

2019 journal article

Practical immunosuppression for autoimmune skin diseases

Vet Pharma, 46(1), 52–54.

By: T. Olivry

Source: NC State University Libraries
Added: September 21, 2020

2019 journal article

Proactive maintenance therapy of canine atopic dermatitis with the anti‐ IL ‐31 lokivetmab. Can a monoclonal antibody blocking a single cytokine prevent allergy flares?

Veterinary Dermatology, 30(2), 98–e26.

By: C. Tamamoto‐Mochizuki n, J. Paps n & T. Olivry n

Contributors: C. Tamamoto-Mochizuki n, J. Paps n & T. Olivry n

TL;DR: Although lokivetmab seems more effective to prevent pruritus than skin lesions in dogs with experimental AD' it also can delay disease flares in some dogs with the spontaneous disease. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, Crossref, NC State University Libraries
Added: April 2, 2019

2019 journal article

The Comparison of Skin Transcriptomes Confirms Canine Atopic Dermatitis Is a Natural Homologue to the Human Disease

Journal of Investigative Dermatology, 139(4), 968–971.

By: J. Freudenberg*, T. Olivry n, D. Mayhew*, D. Rubenstein* & D. Rajpal*

Contributors: J. Freudenberg*, T. Olivry n, D. Mayhew*, D. Rubenstein* & D. Rajpal*

MeSH headings : Animals; Dermatitis, Atopic / genetics; Dermatitis, Atopic / metabolism; Dermatitis, Atopic / pathology; Dog Diseases / genetics; Dog Diseases / metabolism; Dog Diseases / pathology; Dogs; Humans; RNA, Messenger / genetics; Skin / pathology; Transcriptome / genetics
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, Crossref, NC State University Libraries
Added: April 2, 2019

2019 journal article

The role of oclacitinib in the management of ischaemic dermatopathy in four dogs

Veterinary Dermatology, 30(3), 201–e63.

By: B. Levy n, K. Linder n & T. Olivry n

Contributors: B. Levy n, K. Linder n & T. Olivry n

MeSH headings : Animals; Autoimmune Diseases / drug therapy; Autoimmune Diseases / veterinary; Dermatitis, Atopic / drug therapy; Dermatitis, Atopic / veterinary; Dermatologic Agents / administration & dosage; Dermatologic Agents / therapeutic use; Dog Diseases / drug therapy; Dogs; Female; Glucocorticoids / therapeutic use; Male; Pyrimidines / administration & dosage; Pyrimidines / therapeutic use; Skin Diseases / drug therapy; Skin Diseases / veterinary; Sulfonamides / administration & dosage; Sulfonamides / therapeutic use; Treatment Outcome
TL;DR: Oclacitinib was a useful immunosuppressive adjuvant to oral glucocorticoids for the treatment of refractory or severe cases of ischaemic dermatopathy in these four dogs, and warrants further studies of the safety, efficacy and mechanism of action of oclac itinib as an Immunosuppressant. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, Crossref, NC State University Libraries
Added: May 28, 2019

2019 journal article

The usefulness of short‐course prednisolone during the initial phase of an elimination diet trial in dogs with food‐induced atopic dermatitis

Veterinary Dermatology, 30(6), 498–e149.

MeSH headings : Animal Feed / adverse effects; Animals; Dermatitis, Atopic / etiology; Dermatitis, Atopic / prevention & control; Dermatitis, Atopic / veterinary; Diet / adverse effects; Diet / veterinary; Dog Diseases / etiology; Dog Diseases / prevention & control; Dogs; Drug Administration Schedule / veterinary; Female; Food Hypersensitivity / prevention & control; Food Hypersensitivity / veterinary; Male; Prednisolone / administration & dosage
TL;DR: This study demonstrates that a shorter EDT is possible if the allergic pruritus and inflammation are initially controlled with a short course of glucocorticoids and is likely to improve owner adherence and facilitate the diagnosis of food allergy. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: ORCID
Added: October 17, 2019

2019 journal article

Treatment of canine atopic dermatitis: time to revise our strategy?

Veterinary Dermatology, 30(2), 87–90.

By: T. Olivry n & F. Banovic*

Contributors: T. Olivry n & F. Banovic*

UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, Crossref, NC State University Libraries
Added: April 2, 2019

2019 journal article

What’s new for treatment of atopic dermatitis

Vet Pharma, 46(1), 55–59.

By: T. Olivry

Source: NC State University Libraries
Added: September 21, 2020

2018 journal article

A Toxocara canis infection influences the immune response to house dust mite allergens in dogs

Veterinary Immunology and Immunopathology, 202, 11–17.

author keywords: Atopic dermatitis; Toxocara canis infection; Hygiene hypothesis; Allergy pathogenesis
MeSH headings : Allergens / immunology; Animals; Antibodies, Helminth / blood; Antigens, Dermatophagoides / immunology; Dermatitis, Atopic / veterinary; Dermatophagoides farinae; Disease Models, Animal; Dog Diseases / immunology; Dog Diseases / parasitology; Dogs; Female; Immunoglobulin E / blood; Immunoglobulin G / blood; Male; Skin / parasitology; Skin / pathology; Skin Tests; Toxocara canis; Toxocariasis / complications; Toxocariasis / immunology
TL;DR: It is suggested that a Tc infection increases the sensitization to Df in dogs and the possible protective effect against Df-induced clinical signs after allergen challenge should be confirmed in larger studies. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Crossref, NC State University Libraries, ORCID
Added: August 29, 2019

2018 journal article

A pilot study of total and allergen-specific IgE serum levels during anestrous, estrous and pregnancy in healthy female dogs

Veterinary Dermatology, 29(4), 329–e115.

By: N. Tarpataki*, J. Thuróczy*, N. Fischer*, S. Jacquenet, A. Rostaher*, C. Richard, L. Zwickl*, T. Olivry n, C. Favrot*

Contributors: N. Tarpataki*, J. Thuróczy*, N. Fischer*, S. Jacquenet, A. Rostaher*, C. Richard, L. Zwickl*, T. Olivry n, C. Favrot*

TL;DR: Total IgE serum levels are reduced during pregnancy in female dogs, however, results of one allergen-specific IgE test did not appear to be markedly altered by the reproductive cycle in healthy bitches. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: August 29, 2019

2018 journal article

Auto-immune skin diseases in animals: time to reclassify and review after 40 years

BMC Veterinary Research, 14(1).

By: T. Olivry n

Contributors: T. Olivry n

MeSH headings : Animals; Autoimmune Diseases / classification; Autoimmune Diseases / veterinary; Dog Diseases / classification; Dog Diseases / immunology; Dogs; Skin Diseases / classification; Skin Diseases / immunology; Skin Diseases / veterinary
TL;DR: This Editorial introduces a series of comprehensive review papers on the various canine and feline AISDs by summarizing the key historical, clinical, histological, immunological and treatment characteristics of animal AISD. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries, ORCID
Added: September 28, 2019

2018 journal article

Cornstarch is less allergenic than corn flour in dogs and cats previously sensitized to corn

BMC Veterinary Research, 14(1).

By: T. Olivry n & J. Bexley*

Contributors: T. Olivry n & J. Bexley*

author keywords: Allergen; Allergy; Canine; Diet; Food; Feline; Corn; IgE; Maize; Starch
MeSH headings : Allergens / immunology; Animals; Cat Diseases / immunology; Cats; Dog Diseases / immunology; Dogs; Enzyme-Linked Immunosorbent Assay / veterinary; Flour / adverse effects; Food Hypersensitivity / etiology; Food Hypersensitivity / immunology; Food Hypersensitivity / veterinary; Immunoglobulin E / immunology; Starch / adverse effects; Starch / immunology; Zea mays / immunology
TL;DR: It is suggested that pet foods containing cornstarch as a carbohydrate source are preferable for dogs and cats suspected of suffering from corn allergy, because IgE from corn-sensitized dogs are less likely to recognize allergens in cornst starch than in kernel and flour extracts. (via Semantic Scholar)
Sources: Web Of Science, ORCID, Crossref, NC State University Libraries
Added: August 6, 2018

2018 journal article

Could we use the erythema grading of the CADESI4 as a simple instrument for future short-duration clinical trials of dogs with atopic dermatitis?

Veterinary Dermatology, 30(1), 80–81.

By: T. Olivry n

Contributors: T. Olivry n

MeSH headings : Animals; Clinical Trials, Veterinary as Topic; Dermatitis, Atopic / diagnosis; Dermatitis, Atopic / pathology; Dermatitis, Atopic / veterinary; Dog Diseases / diagnosis; Dog Diseases / pathology; Dogs; Erythema / diagnosis; Erythema / pathology; Erythema / veterinary; Reproducibility of Results; Severity of Illness Index; Skin / pathology
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, Crossref, NC State University Libraries
Added: January 28, 2019

2018 journal article

Critically appraised topic on adverse food reactions of companion animals (5): discrepancies between ingredients and labeling in commercial pet foods

BMC VETERINARY RESEARCH, 14(1).

By: T. Olivry n & R. Mueller*

Contributors: T. Olivry n & R. Mueller*

author keywords: Canine; Cat; Contamination; Diet; Dog; Feline; Food allergy; Labeling; Pet foods
MeSH headings : Animal Feed / analysis; Animals; Cats; Diet / veterinary; Dogs; Food Contamination; Food Hypersensitivity / veterinary; Food Labeling
TL;DR: The mislabeling of pet foods appears rather common, even in those with “novel” or “limited” ingredients proposed for elimination diets, and Unexpected added ingredients are more frequently detected than those missing from the label. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2018 journal article

Critically appraised topic on adverse food reactions of companion animals (6): prevalence of noncutaneous manifestations of adverse food reactions in dogs and cats

BMC Veterinary Research, 14(1).

By: R. Mueller* & T. Olivry n

Contributors: R. Mueller* & T. Olivry n

author keywords: Canine; Feline; Food allergy; Gastroenteritis; Vomiting; Diarrhoea
MeSH headings : Animals; Cat Diseases / diagnosis; Cat Diseases / etiology; Cat Diseases / pathology; Cats; Diarrhea / etiology; Diarrhea / veterinary; Dog Diseases / diagnosis; Dog Diseases / etiology; Dog Diseases / pathology; Dogs; Food Hypersensitivity / diagnosis; Food Hypersensitivity / etiology; Food Hypersensitivity / pathology; Food Hypersensitivity / veterinary; Vomiting / etiology; Vomiting / veterinary
TL;DR: An elimination diet should be considered early in the work-up of dogs and cats with chronic vomiting and diarrhoea and other non-cutaneous signs occur less commonly because of AFRs. (via Semantic Scholar)
Sources: Web Of Science, ORCID, Crossref, NC State University Libraries
Added: December 3, 2018

2018 journal article

Cutaneous lupus erythematosus in dogs: a comprehensive review

BMC Veterinary Research, 14(1).

By: T. Olivry n, K. Linder n & F. Banovic*

Contributors: T. Olivry n, K. Linder n & F. Banovic*

author keywords: Auto-immune skin diseases; Auto-immunity; Canine; Dermatology; Lupus; Skin
MeSH headings : Animals; Dog Diseases / classification; Dog Diseases / diagnosis; Dog Diseases / pathology; Dogs; Lupus Erythematosus, Cutaneous / classification; Lupus Erythematosus, Cutaneous / diagnosis; Lupus Erythematosus, Cutaneous / pathology; Lupus Erythematosus, Cutaneous / veterinary
TL;DR: An adaptation of the Gilliam-Sontheimer classification of CLE for dogs is proposed and the signalment, clinical signs, laboratory and histopathology and treatment outcome of the currently recognized variants of canine CLE are reviewed. (via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: August 29, 2019

2018 journal article

Development of a core outcome set for therapeutic clinical trials enrolling dogs with atopic dermatitis (COSCAD’18)

BMC Veterinary Research, 14(1), 238.

By: T. Olivry n, E. Bensignor, C. Favrot*, C. Griffin, P. Hill*, R. Mueller*, J. Plant, H. Williams*

Contributors: T. Olivry n, E. Bensignor, C. Favrot*, C. Griffin, P. Hill*, R. Mueller*, J. Plant, H. Williams*

author keywords: Allergy; Atopic dermatitis; Canine; Clinical trial; Core outcome set; Outcome measures
MeSH headings : Animals; Clinical Trials as Topic / methods; Clinical Trials as Topic / veterinary; Dermatitis, Atopic / pathology; Dermatitis, Atopic / veterinary; Dermatologic Agents / therapeutic use; Dog Diseases / pathology; Dogs; Pruritus / classification; Pruritus / veterinary; Severity of Illness Index; Treatment Outcome
TL;DR: The COSCAD’18 has three outcome measures: the percentages of dogs with veterinarian-assessed skin lesions or owner-rated pruritus manifestation scores in the range of normal dogs or those with mild AD; the third is a good-to-excellent global assessment by the pet owners of their perception of treatment efficacy. (via Semantic Scholar)
Sources: Web Of Science, ORCID, Crossref, NC State University Libraries
Added: October 19, 2018

2018 article

Diluted sodium hypochlorite (bleach) in dogs: antiseptic efficacy, local tolerability and in vitro effect on skin barrier function and inflammation

Banovic, F., Olivry, T., Baumer, W., Paps, J., Stahl, J., Rogers, A., & Jacob, M. (2018, February). VETERINARY DERMATOLOGY, Vol. 29.

By: F. Banovic n, T. Olivry n, W. Baumer n, J. Paps n, J. Stahl*, A. Rogers n, M. Jacob n

Contributors: F. Banovic n, T. Olivry n, W. Bäumer n, J. Paps n, J. Stahl*, A. Rogers n, M. Jacob n

MeSH headings : Administration, Cutaneous; Animals; Anti-Infective Agents / administration & dosage; Anti-Infective Agents / pharmacology; Anti-Infective Agents, Local / administration & dosage; Anti-Infective Agents, Local / pharmacology; Cell Survival / drug effects; Dogs; Inflammation / drug therapy; Keratinocytes / drug effects; Male; Skin / drug effects; Sodium Hypochlorite / administration & dosage; Sodium Hypochlorite / pharmacology
TL;DR: The results indicate that a topical diluted bleach solution, at either 0.05 or 0.005% hypochlorite concentrations, is a well-tolerated antiseptic that also exhibits anti-inflammatory properties. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 6, 2018

2018 journal article

Glucocorticosteroids and ciclosporin do not significantly impact canine cutaneous microbiota

BMC VETERINARY RESEARCH, 14(1).

By: G. Widmer*, L. Ferrer*, C. Favrot*, J. Paps n, K. Huynh* & T. Olivry n

Contributors: G. Widmer*, L. Ferrer*, C. Favrot*, J. Paps n, K. Huynh* & T. Olivry n

author keywords: Prednisone; Ciclosporin; 16S amplicon sequencing; Microbiota; Malassezia; Papillomavirus; Principal coordinates analysis
MeSH headings : Animals; Cyclosporine / pharmacology; Dermatomycoses / chemically induced; Dermatomycoses / veterinary; Dog Diseases / chemically induced; Dog Diseases / microbiology; Dog Diseases / virology; Dogs / microbiology; Female; Immunosuppressive Agents / pharmacology; Malassezia / metabolism; Male; Microbiota / drug effects; Papillomaviridae / metabolism; Papillomavirus Infections / chemically induced; Papillomavirus Infections / veterinary; Prednisone / pharmacology; Skin / drug effects; Skin / microbiology; Skin / virology
TL;DR: Ciclosporin and prednisone at doses used for the treatment of atopic dermatitis do not impact the canine cutaneous microbiota in a detectable manner. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 6, 2018

2018 journal article

Neuromedin B: Characterization of a novel peripheral pruritogen

Journal of Veterinary Pharmacology and Therapeutics, 41, 48–48.

By: S. Ehling, M. Ko, T. Fukuyama, T. Olivry & W. Baumer

Source: NC State University Libraries
Added: August 6, 2018

2018 journal article

Pilot evaluation of the antipruritic efficacy of a topical transient receptor potential melastatin subfamily 8 (TRPM8) agonist in dogs atopic dermatitis and pedal pruritus

Veterinary Dermatology, 29(1), 29–14.

By: C. Tamamoto-Mochizuki n, K. Murphy n & T. Olivry n

Contributors: C. Tamamoto-Mochizuki n, K. Murphy n & T. Olivry n

MeSH headings : Administration, Cutaneous; Animals; Antipruritics / administration & dosage; Antipruritics / therapeutic use; Dermatitis, Atopic / drug therapy; Dermatitis, Atopic / veterinary; Dermatologic Agents / administration & dosage; Dermatologic Agents / therapeutic use; Dog Diseases / drug therapy; Dogs; Foot Diseases / drug therapy; Foot Diseases / veterinary; Pilot Projects; Pruritus / drug therapy; Pruritus / veterinary; TRPM Cation Channels / agonists
TL;DR: In this pilot trial with a TRPM8 agonist in atopic dogs with pedal pruritus, the twice daily application of a 2% Cryosim-1 cream did not have an antipruritic effect superior to that of its vehicle. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: April 10, 2020

2018 journal article

Serum IgE cross-reactivity between fish and chicken meats in dogs

Veterinary Dermatology, 30(1), 25–e8.

By: J. Bexley*, N. Kingswell* & T. Olivry n

Contributors: J. Bexley*, N. Kingswell* & T. Olivry n

MeSH headings : Animals; Chickens / immunology; Cross Reactions / immunology; Dermatitis, Atopic / etiology; Dermatitis, Atopic / immunology; Dermatitis, Atopic / veterinary; Dogs / immunology; Enzyme-Linked Immunosorbent Assay / veterinary; Fishes / immunology; Food Hypersensitivity / etiology; Food Hypersensitivity / immunology; Food Hypersensitivity / veterinary; Gadus morhua / immunology; Immunoblotting / veterinary; Immunoglobulin E / immunology; Meat; Meat Proteins / immunology; Salmon / immunology
TL;DR: Whether any of these newly identified IgE cross-reactive chicken-fish allergens is the cause of clinical allergy needs to be determined in dogs reacting to at least two of these common food sources. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, Crossref, NC State University Libraries
Added: January 28, 2019

2017 journal article

Apoptosis as a Mechanism for Keratinocyte Death in Canine Toxic Epidermal Necrolysis

Veterinary Pathology, 54(2), 249–253.

By: F. Banovic n, S. Dunston n, K. Linder n, P. Rakich* & T. Olivry n

Contributors: F. Banovic n, S. Dunston n, K. Linder n, P. Rakich* & T. Olivry n

author keywords: apoptosis; skin; erythema multiforme; toxic epidermal necrolysis
MeSH headings : Animals; Apoproteins / physiology; Caspase 3 / genetics; Caspase 3 / metabolism; DNA Nucleotidylexotransferase / metabolism; Deoxyuracil Nucleotides / metabolism; Dog Diseases / pathology; Dogs; Gene Expression Regulation, Enzymologic; In Situ Nick-End Labeling; Keratinocytes / pathology; Stevens-Johnson Syndrome / pathology; Stevens-Johnson Syndrome / veterinary
TL;DR: Results suggest that apoptosis of epidermal keratinocytes and lymphocytic satellitosis represent one of the early steps in the pathogenesis of canine TEN, as in the human disease counterpart. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: ORCID
Added: August 29, 2019

2017 journal article

Clinical, microscopic and microbial characterization of exfoliative superficial pyoderma-associated epidermal collarettes in dogs

Veterinary Dermatology, 28(1), 107–e23.

By: F. Banovic n, K. Linder n & T. Olivry n

Contributors: F. Banovic n, K. Linder n & T. Olivry n

MeSH headings : Animals; Dog Diseases / diagnosis; Dog Diseases / microbiology; Dog Diseases / pathology; Dogs; Exotoxins / genetics; In Situ Hybridization, Fluorescence / veterinary; Male; Pyoderma / diagnosis; Pyoderma / microbiology; Pyoderma / pathology; Pyoderma / veterinary; Skin / microbiology; Skin / pathology; Staphylococcal Skin Infections / diagnosis; Staphylococcal Skin Infections / microbiology; Staphylococcal Skin Infections / pathology; Staphylococcal Skin Infections / veterinary; Staphylococcus / genetics
TL;DR: Epidermal collarettes represent unique clinical and histological lesions of exfoliative superficial pyodermas that are distinct from those of impetigo and superficial bacterial folliculitis and the role of corneodesmosin in collarette pathogenesis deserve further investigation. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: ORCID
Added: August 29, 2019

2017 journal article

Critically appraised topic on adverse food reactions of companion animals (3): prevalence of cutaneous adverse food reactions in dogs and cats

BMC VETERINARY RESEARCH, 13(1).

By: T. Olivry n & R. Mueller*

Contributors: T. Olivry n & R. Mueller*

author keywords: Allergy; Atopic Dermatitis; Canine; Cat; Dog; Feline; Food Allergy; Itch; Pruritus
MeSH headings : Animal Feed; Animals; Cat Diseases / epidemiology; Cat Diseases / immunology; Cats; Dermatitis / epidemiology; Dermatitis / immunology; Dermatitis / veterinary; Dog Diseases / epidemiology; Dog Diseases / immunology; Dogs; Food Hypersensitivity / epidemiology; Food Hypersensitivity / veterinary; Pets; Prevalence; Pruritus / epidemiology; Pruritus / immunology; Pruritus / veterinary
TL;DR: Among dogs and cats with pruritus and those suspected of allergic skin disease, the prevalence of CAFR is high enough to justify this syndrome to be ruled-out with a restriction (elimination)-provocation dietary trial. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2017 journal article

Critically appraised topic on adverse food reactions of companion animals (4): can we diagnose adverse food reactions in dogs and cats with in vivo or in vitro tests?

BMC VETERINARY RESEARCH, 13(1).

By: R. Mueller* & T. Olivry n

Contributors: R. Mueller* & T. Olivry n

author keywords: Atopic; Canine; Feline; Food allergy; Gastroenteritis; In vitro; Serum test; IgE
MeSH headings : Animals; Cat Diseases / diagnosis; Cats; Diet; Dog Diseases / diagnosis; Dogs; Food Hypersensitivity / diagnosis; Food Hypersensitivity / veterinary; Immunologic Tests / methods; Immunologic Tests / veterinary
TL;DR: Testing for serum food-specific IgE and IgG showed low repeatability and, in dogs, a highly variable accuracy, and in cats, the accuracy of testing for food- specific IgE was low, indicating the best diagnostic procedure to identify AFRs in small animals remains an elimination diet with subsequent provocation trials. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2017 journal article

Epidermolysis bullosa simplex in sibling Eurasier dogs is caused by a PLEC non‐sense variant

Veterinary Dermatology, 28(1), 10–e3.

By: E. Mauldin*, P. Wang*, T. Olivry n, P. Henthorn* & M. Casal*

Contributors: E. Mauldin*, P. Wang*, T. Olivry n, P. Henthorn* & M. Casal*

MeSH headings : Animals; Codon, Nonsense / genetics; Codon, Nonsense / physiology; Dog Diseases / genetics; Dog Diseases / pathology; Dogs / genetics; Epidermolysis Bullosa Simplex / genetics; Epidermolysis Bullosa Simplex / pathology; Epidermolysis Bullosa Simplex / veterinary; Female; Male; Pedigree; Plectin / genetics; Plectin / physiology; Siblings; Skin / pathology
TL;DR: This study describes the first documented spontaneous EBS associated with a PLEC variant in domestic animals and describes a novel blistering disease that arose spontaneously in a litter of puppies. (via Semantic Scholar)
Sources: ORCID, NC State University Libraries, NC State University Libraries
Added: August 6, 2018

2017 journal article

Evaluation of intraepidermal nerve fibres in the skin of normal and atopic dogs

Veterinary Dermatology, 28(4), 355–e80.

By: A. Laprais n, S. Dunston n, S. Torres*, C. Favrot* & T. Olivry n

Contributors: A. Laprais n, S. Dunston n, S. Torres*, C. Favrot* & T. Olivry n

MeSH headings : Animals; Biopsy; Dermatitis, Atopic / pathology; Dermatitis, Atopic / veterinary; Dog Diseases / pathology; Dogs; Nerve Fibers / pathology; Paraffin Embedding / veterinary; Skin / innervation; Skin / pathology
TL;DR: IENFs are detected more commonly in canine AD than in normal haired skin; these results are comparable to those seen for human AD. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: ORCID, Crossref, NC State University Libraries
Added: August 29, 2019

2017 journal article

Extensive protein hydrolyzation is indispensable to prevent IgE-mediated poultry allergen recognition in dogs and cats

BMC VETERINARY RESEARCH, 13(1).

By: T. Olivry n, J. Bexley* & I. Mougeot

Contributors: T. Olivry n, J. Bexley* & I. Mougeot

author keywords: Allergy; Canine; Food; Feline; Hydrolysate; Hypersensitivity; IgE
MeSH headings : Allergens / immunology; Animal Feed / adverse effects; Animals; Cat Diseases / immunology; Cats / immunology; Chickens / immunology; Dog Diseases / immunology; Dogs / immunology; Enzyme-Linked Immunosorbent Assay / veterinary; Epitopes / immunology; Feathers / immunology; Food Hypersensitivity / immunology; Food Hypersensitivity / veterinary; Immunoglobulin E / immunology
TL;DR: It is suggested that an extensive—but not partial—hydrolyzation of the poultry feather extract is necessary to prevent the recognition of allergenic epitopes by poultry-specific IgE. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2017 journal article

Is CCNU (lomustine) valuable for treatment of cutaneous epitheliotropic lymphoma in dogs? A critically appraised topic

BMC VETERINARY RESEARCH, 13(1).

By: A. Laprais n & T. Olivry n

Contributors: A. Laprais n & T. Olivry n

author keywords: Canine; Chemotherapy; Dog; Epitheliotropic; Lomustine; Lymphosarcoma; Mycosis fungoides; Neoplasia
MeSH headings : Animals; Antineoplastic Agents, Alkylating / therapeutic use; Dog Diseases / drug therapy; Dogs; Lomustine / therapeutic use; Lymphoma, T-Cell, Cutaneous / drug therapy; Lymphoma, T-Cell, Cutaneous / veterinary; Remission Induction; Treatment Outcome
TL;DR: The search for, and review and analysis of, the best evidence available suggests that CCNU and pegylated liposomal doxorubicin appear to yield the highest rate of complete remission in approximately one-third of dogs with CTCL. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2017 personal communication

Janus kinase inhibitors display broad anti-itch properties: A possible link through the TRPV1 receptor

Fukuyama, T., Ganchingco, J. R., Mishra, S. K., Olivry, T., Rzagalinski, I., Volmer, D. A., & Baeumer, W. (2017, July).

By: T. Fukuyama n, J. Ganchingco n, S. Mishra n, T. Olivry n, I. Rzagalinski*, D. Volmer*, W. Baeumer

Contributors: T. Fukuyama n, J. Ganchingco n, S. Mishra n, T. Olivry n, I. Rzagalinski*, D. Volmer*, W. Bäumer n

MeSH headings : Animals; Antipruritics / chemistry; Antipruritics / pharmacology; Dopaminergic Neurons / drug effects; Dopaminergic Neurons / metabolism; Female; Humans; Janus Kinase Inhibitors / chemistry; Janus Kinase Inhibitors / pharmacology; Mice; Models, Molecular; Molecular Conformation; Molecular Imaging / methods; Protein Binding; Sensory Receptor Cells / drug effects; Sensory Receptor Cells / metabolism; Structure-Activity Relationship; TRPV Cation Channels / antagonists & inhibitors; TRPV Cation Channels / chemistry; TRPV Cation Channels / metabolism
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2017 journal article

Proof of concept of the preventive efficacy of high‐dose recombinant mono‐allergen immunotherapy in atopic dogs sensitized to the Dermatophagoides farinae allergen Der f 2

Veterinary Dermatology, 28(2), 183–e40.

By: T. Olivry n, J. Paps n & S. Dunston n

Contributors: T. Olivry n, J. Paps n & S. Dunston n

MeSH headings : Animals; Antigens, Dermatophagoides / administration & dosage; Antigens, Dermatophagoides / immunology; Arthropod Proteins / administration & dosage; Arthropod Proteins / immunology; Dermatitis, Atopic / immunology; Dermatitis, Atopic / veterinary; Desensitization, Immunologic / veterinary; Dog Diseases / immunology; Dogs; Dose-Response Relationship, Immunologic; Intradermal Tests; Recombinant Proteins / immunology; Subcutaneous Absorption
TL;DR: The new mono-allergen SCIT appears safe and effective for reducing skin lesions after allergen challenges; it deserves further testing in dogs with spontaneous atopic dermatitis. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: ORCID
Added: August 29, 2019

2017 journal article

The novel high molecular weight Dermatophagoides farinae protein Zen‐1 is a major allergen in North American and European mite allergic dogs with atopic dermatitis

Veterinary Dermatology, 28(2), 177–e38.

By: T. Olivry n, S. Dunston n, C. Favrot*, P. Prélaud & T. Tsukui*

Contributors: T. Olivry n, S. Dunston n, C. Favrot*, P. Prélaud & T. Tsukui*

MeSH headings : Animals; Antibody Specificity; Antigens, Dermatophagoides / immunology; Dermatitis, Atopic / epidemiology; Dermatitis, Atopic / immunology; Dermatitis, Atopic / veterinary; Dog Diseases / epidemiology; Dog Diseases / immunology; Dogs; Enzyme-Linked Immunosorbent Assay / veterinary; Europe / epidemiology; Immunoglobulin E / blood; Immunoglobulin E / immunology; Insect Proteins / immunology; Intradermal Tests / veterinary; United States / epidemiology
TL;DR: This study establishes Zen-1 as a major allergen in atopic dogs sensitized to Df in American and European Df-hypersensitive dogs and establishes the likely relevance of serological results. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: ORCID
Added: August 29, 2019

2017 journal article

Therapeutic effectiveness of calcineurin inhibitors in canine vesicular cutaneous lupus erythematosus

Veterinary Dermatology, 28(5), 493–e115.

By: F. Banovic n, D. Robson, M. Linek & T. Olivry n

Contributors: F. Banovic n, D. Robson, M. Linek & T. Olivry n

MeSH headings : Administration, Cutaneous; Administration, Oral; Animals; Calcineurin Inhibitors / administration & dosage; Calcineurin Inhibitors / therapeutic use; Cyclosporine / administration & dosage; Cyclosporine / adverse effects; Cyclosporine / therapeutic use; Dog Diseases / drug therapy; Dog Diseases / pathology; Dogs; Drug Therapy, Combination / veterinary; Female; Lupus Erythematosus, Cutaneous / drug therapy; Lupus Erythematosus, Cutaneous / pathology; Lupus Erythematosus, Cutaneous / veterinary; Male; Skin / pathology; Tacrolimus / administration & dosage; Tacrolimus / adverse effects; Tacrolimus / analogs & derivatives; Tacrolimus / therapeutic use; Treatment Outcome
TL;DR: Observations support CIs as the preferable therapeutic alternatives to long-term immunosuppression with oral glucocorticoids in dogs with VCLE. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: August 29, 2019

2017 journal article

Translational animal models of atopic dermatitis for preclinical studies

Yale Journal of Biology and Medicine, 90(3), 389–402. http://www.scopus.com/inward/record.url?eid=2-s2.0-85030250721&partnerID=MN8TOARS

By: B. Martel, P. Lovato, W. Bäumer & T. Olivry

Contributors: B. Martel, P. Lovato, W. Bäumer & T. Olivry

Source: ORCID
Added: August 29, 2019

2017 chapter

Treatment of itch in dogs: a mechanistic approach

In Advances in Veterinary Dermatology (pp. 63–70).

By: T. Olivry n & W. Baeumer n

UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: September 28, 2019

2016 journal article

A randomized, double-blinded crossover trial testing the benefit of two hydrolysed poultry-based commercial diets for dogs with spontaneous pruritic chicken allergy

VETERINARY DERMATOLOGY, 27(4), 289–E70.

By: P. Bizikova n & T. Olivry n

Contributors: P. Bizikova n & T. Olivry n

MeSH headings : Animal Feed / analysis; Animals; Chickens; Dermatitis / veterinary; Diet Therapy / veterinary; Dog Diseases / diet therapy; Dogs; Double-Blind Method; Food Hypersensitivity / veterinary; Hydrolysis; Meat / adverse effects; Pruritus / diet therapy; Pruritus / veterinary
TL;DR: The hydrolysed poultry feather diet did not induce pruritus flares in dogs allergic to chicken in contrast to the hydrolysing chicken liver diet that led to pruritis flares in 40% of these dogs. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2016 journal article

An update on the treatment of canine atopic dermatitis

The Veterinary Journal, 207, 29–37.

By: M. Saridomichelakis* & T. Olivry n

Contributors: M. Saridomichelakis* & T. Olivry n

author keywords: Atopic dermatitis; Dog; Ciclosporin; Glucocorticoids; Oclacitinib
MeSH headings : Animals; Dermatitis, Atopic / veterinary; Dermatologic Agents / therapeutic use; Dog Diseases / drug therapy; Dogs; Glucocorticoids / therapeutic use; Pyrimidines / therapeutic use; Sulfonamides / therapeutic use
TL;DR: Treatment modalities of lower or less proven efficacy include antihistamines, dextromethorphan, fatty acids, feline interferon-omega, misoprostol, pentoxifylline, specific serotonin re-uptake inhibitors and tricyclic antidepressant drugs. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Crossref, NC State University Libraries, ORCID
Added: September 28, 2019

2016 journal article

Autosomal recessive congenital ichthyosis due to PNPLA1 mutation in a golden retriever–poodle cross-bred dog and the effect of topical therapy

Veterinary Dermatology, 27(4), 306–e75.

Contributors: C. Tamamoto-Mochizuki n, F. Banovic n, P. Bizikova n, A. Laprais n, K. Linder n & T. Olivry n

TL;DR: The long-term combination of oral fatty acids and topical therapy appeared to be beneficial in this case and is the first case report of ARCI with homozygous PNPLA1 mutation in a golden retriever-poodle cross-bred dog. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: ORCID
Added: August 29, 2019

2016 journal article

Chronological clinical and pathological documentation of porcine ulcerative dermatitis

VETERINARY DERMATOLOGY, 27(4), 315–E78.

By: F. Zeeh*, M. Suter*, E. Mueller*, N. Brunisholz*, W. Zimmerman*, M. Ricklin*, S. Rufenacht*, T. Olivry n, P. Roosje*

Contributors: F. Zeeh*, M. Suter*, E. Mueller*, N. Brünisholz*, W. Zimmerman*, M. Ricklin*, S. Rüfenacht*, T. Olivry n, P. Roosje*

TL;DR: The findings in this case report link gestation with the development of clinical signs and histological changes and it seems advisable to cull breeding sows after they have developed PUDS. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
5. Gender Equality (Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2016 journal article

Clinical and microscopic features of generalized discoid lupus erythematosus in dogs (10 cases)

VETERINARY DERMATOLOGY, 27(6), 488-+.

By: F. Banovic n, K. Linder n, M. Uri n, M. Rossi & T. Olivry n

Contributors: F. Banovic n, K. Linder n, M. Uri n, M. Rossi & T. Olivry n

MeSH headings : Animals; Dog Diseases / pathology; Dogs; Female; Lupus Erythematosus, Discoid / pathology; Lupus Erythematosus, Discoid / veterinary; Male; Skin / pathology
TL;DR: Observations support the existence of a canine homologue of human GDLE, a newly recognized canine variant of chronic cutaneous lupus erythematosus that is not well characterized. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2016 journal article

Critically appraised topic on adverse food reactions of companion animals (2): common food allergen sources in dogs and cats

BMC VETERINARY RESEARCH, 12(1).

By: R. Mueller*, T. Olivry n & P. Prelaud

Contributors: R. Mueller*, T. Olivry n & P. Prélaud

author keywords: Allergen; Allergy; Atopic dermatitis; Canine; Cat; Dietary; Dog; Feline; Food allergy
MeSH headings : Allergens; Animals; Cat Diseases / diagnosis; Cat Diseases / diet therapy; Cats; Dog Diseases / diagnosis; Dog Diseases / diet therapy; Dogs; Food Hypersensitivity / diagnosis; Food Hypersensitivity / diet therapy; Food Hypersensitivity / veterinary
TL;DR: In dogs and cats, after a period of dietary restriction leading to the complete remission of clinical signs, food challenges to diagnose CAFR should begin with beef and dairy products, the most commonly recognized food allergens in these two species. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2016 article

Development of an Allergen-induced Atopic Itch Model in Dogs: A Preliminary Report

ACTA DERMATO-VENEREOLOGICA, Vol. 96, pp. 400–401.

By: J. Paps n, W. Baeumer & T. Olivry*

Contributors: J. Paps n, W. Bäumer & T. Olivry*

MeSH headings : Animals; Anti-Allergic Agents / pharmacology; Antigens, Dermatophagoides; Behavior, Animal; Dermatitis, Atopic / drug therapy; Dermatitis, Atopic / immunology; Dermatitis, Atopic / psychology; Disease Models, Animal; Dogs; Glucocorticoids / pharmacology; Motor Activity; Prednisolone / pharmacology; Pruritus / drug therapy; Pruritus / immunology; Pruritus / psychology; Reproducibility of Results; Time Factors
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2016 journal article

Early Activation of Th2/Th22 Inflammatory and Pruritogenic Pathways in Acute Canine Atopic Dermatitis Skin Lesions

JOURNAL OF INVESTIGATIVE DERMATOLOGY, 136(10), 1961–1969.

By: T. Olivry n, D. Mayhew*, J. Paps n, K. Linder n, C. Peredo*, D. Rajpal*, H. Hofland*, J. Cote-Sierra*

Contributors: T. Olivry n, D. Mayhew*, J. Paps n, K. Linder n, C. Peredo*, D. Rajpal*, H. Hofland*, J. Cote-Sierra*

MeSH headings : Adaptive Immunity / immunology; Animals; Cytokines / genetics; Cytokines / immunology; Dermatitis, Atopic / immunology; Dermatophagoides farinae / immunology; Disease Models, Animal; Dogs; Female; Immunity, Innate / immunology; Inflammation / immunology; Interleukin-9 / genetics; Interleukin-9 / immunology; Interleukins / genetics; Interleukins / immunology; Male; Pruritus / immunology; Skin / immunology; Skin / pathology; Species Specificity; Th2 Cells / immunology; Time Factors; Up-Regulation / genetics
TL;DR: Experimental acute canine house dust mite-induced AD lesions exhibit an activation of innate and adaptive immune responses and pruritogenic pathways similar to those seen in humans with acute AD, thereby validating this model to test innovative therapeutics modalities for this disease. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2016 journal article

Mucous membrane pemphigoid in dogs: A retrospective study of 16 new cases

Veterinary Dermatology, 27(5), 376-.

By: H. Tham n, T. Olivry n, K. Linder n & P. Bizikova n

Contributors: H. Tham n, T. Olivry n, K. Linder n & P. Bizikova n

MeSH headings : Animals; Dog Diseases / diagnosis; Dog Diseases / drug therapy; Dog Diseases / pathology; Dogs; Female; Glucocorticoids / therapeutic use; Immunosuppressive Agents / therapeutic use; Male; Pemphigoid, Benign Mucous Membrane / diagnosis; Pemphigoid, Benign Mucous Membrane / drug therapy; Pemphigoid, Benign Mucous Membrane / pathology; Pemphigoid, Benign Mucous Membrane / veterinary; Retrospective Studies; Tetracyclines / therapeutic use
TL;DR: Canine MMP is a chronic and relapsing disease requiring long term treatment, and Combination therapy is often needed to achieve CR. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: ORCID, NC State University Libraries, NC State University Libraries
Added: August 6, 2018

2016 journal article

Necrolytic migratory erythema in a dog

Ankara Universitesi Veteriner Fakultesi Dergisi, 63(1), 83–88.

By: D. Tufenk & T. Olivry

Source: NC State University Libraries
Added: August 6, 2018

2016 journal article

Necrolytic migratory erythema in a dog,Bir köpekte nekrolitik migratuar eritem

Ankara Universitesi Veteriner Fakultesi Dergisi, 63(1), 83–88. http://www.scopus.com/inward/record.url?eid=2-s2.0-84948156639&partnerID=MN8TOARS

By: D. Tüfenk & T. Olivry

Contributors: D. Tüfenk & T. Olivry

Source: ORCID
Added: April 10, 2020

2016 journal article

The skin microbiome in allergen-induced canine atopic dermatitis

VETERINARY DERMATOLOGY, 27(5), 332-+.

By: F. Pierezan*, T. Olivry n, J. Paps n, S. Lawhon*, J. Wu*, J. Steiner*, J. Suchodolski*, A. Hoffmann*

MeSH headings : Animals; Antigens, Dermatophagoides / immunology; Bacteria / classification; Bacteria / genetics; Dermatitis, Atopic / microbiology; Dermatitis, Atopic / veterinary; Dog Diseases / microbiology; Dog Diseases / pathology; Dogs; Female; Male; Pyroglyphidae / microbiology; RNA, Bacterial / genetics; RNA, Ribosomal, 16S / genetics; Skin / microbiology
TL;DR: It is demonstrated that an allergen challenge in sensitized dogs leads to bacterial dysbiosis with increased abundance of S. pseudintermedius at the site of lesion induction. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2015 book

Atopic itch in dogs: Pharmacology and modeling

In Handbook of Experimental Pharmacology (Vol. 226, pp. 357–369).

By: T. Olivry n & W. Bäumer n

Contributors: T. Olivry n & W. Bäumer n

author keywords: Animal model; Atopic dermatitis; Canine; Dog; Pruritus
MeSH headings : Animals; Cyclosporine / therapeutic use; Disease Models, Animal; Dog Diseases / drug therapy; Dogs; Glucocorticoids / therapeutic use; Histamine Antagonists / therapeutic use; Janus Kinase 1 / antagonists & inhibitors; Pruritus / drug therapy; Pruritus / etiology; Pruritus / veterinary
TL;DR: Itch is the most common clinical problem seen in dogs with skin diseases, and the mainstay of treatment of canine atopic itch relies principally on the use of topical and/or oral glucocorticoids and oral cyclosporine. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: ORCID
Added: August 29, 2019

2015 journal article

Canine epidermolysis bullosa acquisita: A retrospective study of 20 cases

Veterinary Dermatology, 26(6), 441-.

By: P. Bizikova n, K. Linder n, J. Wofford n, L. Mamo n, S. Dunston n & T. Olivry n

Contributors: P. Bizikova n, K. Linder n, J. Wofford n, L. Mamo n, S. Dunston n & T. Olivry n

MeSH headings : Aging; Animals; Dog Diseases / diagnosis; Dog Diseases / drug therapy; Dog Diseases / pathology; Dogs; Epidermolysis Bullosa Acquisita / pathology; Epidermolysis Bullosa Acquisita / veterinary; Female; Immunologic Factors / administration & dosage; Immunologic Factors / therapeutic use; Male; Prednisone / administration & dosage; Prednisone / therapeutic use; Retrospective Studies
TL;DR: Canine EBA is a rare subepidermal blistering disease with an inflammatory phenotype and a predilection for young great danes and male dogs and the outcome of treatment appears more favourable than assumed previously. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: ORCID, NC State University Libraries, NC State University Libraries
Added: August 6, 2018

2015 journal article

Clinical Notes: Advances in Veterinary Medicine: therapeutic monoclonal antibodies for companion animals

Clinician’s Brief, 1–4.

By: T. Olivry & G. Bainbridge

Source: NC State University Libraries
Added: September 22, 2020

2015 journal article

Critically appraised topic on adverse food reactions of companion animals (1): duration of elimination diets

BMC VETERINARY RESEARCH, 11(1).

By: T. Olivry n, R. Mueller* & P. Prelaud*

Contributors: T. Olivry n, R. Mueller* & P. Prélaud*

author keywords: Allergy; Atopic dermatitis; Canine; Cat; Dog; Elimination diet; Feline; Food allergy; Itch; Pruritus
MeSH headings : Animal Feed / adverse effects; Animals; Cat Diseases / diagnosis; Cats; Diet / veterinary; Dog Diseases / diagnosis; Dogs; Food Hypersensitivity / diagnosis; Food Hypersensitivity / veterinary
TL;DR: For diagnosing CAFRs in more than 90 % of dogs and cats, elimination diet trials should last at least 8 weeks. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2015 journal article

Deep pyoderma caused by Burkholderia cepacia complex associated with ciclosporin administration in dogs: a case series

VETERINARY DERMATOLOGY, 26(4), 287-+.

By: F. Banovic n, S. Koch*, D. Robson, M. Jacob n & T. Olivry n

Contributors: F. Banovic n, S. Koch*, D. Robson, M. Jacob n & T. Olivry n

MeSH headings : Animals; Anti-Bacterial Agents / therapeutic use; Burkholderia Infections / complications; Burkholderia Infections / drug therapy; Burkholderia Infections / pathology; Burkholderia Infections / veterinary; Burkholderia cepacia complex; Cyclosporine / adverse effects; Dog Diseases / diagnosis; Dog Diseases / drug therapy; Dog Diseases / microbiology; Dog Diseases / pathology; Dogs; Immunocompromised Host; Immunosuppressive Agents / adverse effects; Male; Pyoderma / etiology; Pyoderma / pathology; Pyoderma / veterinary; Retrospective Studies; Skin / microbiology; Skin / pathology
TL;DR: Clinicians should be aware of the rare potential for Bcc-associated deep skin infections in dogs receiving oral ciclosporin and owners should be made conscious of the potential transmission risk to humans or other animals. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2015 journal article

Evaluation of a DLA-79 allele associated with multiple immune-mediated diseases in dogs

Immunogenetics, 68(3), 205–217.

By: S. Friedenberg n, G. Buhrman n, L. Chdid n, N. Olby n, T. Olivry n, J. Guillaumin*, T. O’Toole*, R. Goggs* ...

Contributors: S. Friedenberg n, G. Buhrman n, L. Chdid n, N. Olby n, T. Olivry n, J. Guillaumin*, T. O’Toole*, R. Goggs* ...

author keywords: Canine; Immune-mediated disease; Dog leukocyte antigen; Major histocompatibility complex class Ib
MeSH headings : Alleles; Amino Acid Substitution; Animals; Autoimmune Diseases / genetics; Autoimmune Diseases / immunology; Binding Sites; Dog Diseases / genetics; Dog Diseases / immunology; Dogs; Exons; Gene Frequency; Genetic Predisposition to Disease; Genotype; Histocompatibility Antigens Class I / chemistry; Histocompatibility Antigens Class I / genetics; Histocompatibility Antigens Class I / immunology; Immune System Diseases / veterinary; Meta-Analysis as Topic; Models, Molecular; Peptides / chemistry; Peptides / metabolism; Phenotype; Polymorphism, Single Nucleotide; Protein Conformation; Reproducibility of Results; Structure-Activity Relationship
TL;DR: A strong association is demonstrated between two polymorphic positions (10 bp apart) in exon 2 of one allele in D LA-79, DLA-79*001:02, and multiple immune-mediated diseases, resulting in F33L and N37D amino acid changes that are likely to affect critical interactions with the peptide N-terminus. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018

2015 journal article

Expression patterns of superficial epidermal adhesion molecules in an experimental dog model of acute atopic dermatitis skin lesions

VETERINARY DERMATOLOGY, 26(1), 53-+.

By: T. Olivry n & S. Dunston n

Contributors: T. Olivry n & S. Dunston n

MeSH headings : Animals; Cell Adhesion Molecules / metabolism; Dermatitis, Atopic / metabolism; Dermatitis, Atopic / pathology; Dermatitis, Atopic / veterinary; Dog Diseases / metabolism; Dog Diseases / pathology; Dogs; Epidermis / metabolism; Epidermis / pathology; Fluorescent Antibody Technique, Indirect / veterinary; Patch Tests / veterinary; Transcriptome
TL;DR: It is suggested that HDM allergens, via proteolytic digestion and/or because of induced allergic inflammation, affect the expression and possible function of corneodesmosomal and tight junction proteins. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2015 journal article

Generalized Canine Discoid Lupus Erythematosus Responsive to Tetracycline and Niacinamide Therapy

JOURNAL OF THE AMERICAN ANIMAL HOSPITAL ASSOCIATION, 51(3), 171–175.

By: M. Rossi n, L. Messenger, K. Linder n & T. Olivry n

Contributors: M. Rossi n, L. Messenger, K. Linder n & T. Olivry n

MeSH headings : Animals; Dog Diseases / drug therapy; Dogs; Drug Therapy, Combination; Immunomodulation / drug effects; Lupus Erythematosus, Discoid / drug therapy; Lupus Erythematosus, Discoid / veterinary; Male; Niacinamide / therapeutic use; Protein Synthesis Inhibitors / therapeutic use; Tetracycline / therapeutic use; Vitamin B Complex / therapeutic use
TL;DR: An 11 yr old shih tzu that presented with skin lesions consisting of multiple annular, erythematous papules and plaques, hyperpigmentation, adherent scaling, and atrophic scars over the caudal dorsum, flanks, craniodorsal thorax, and lateroproximal extremities is described. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2015 journal article

Mucocutaneous lupus erythematosus in dogs (21 cases)

VETERINARY DERMATOLOGY, 26(4), 256-+.

By: T. Olivry n, M. Rossi, F. Banovic n & K. Linder n

Contributors: T. Olivry n, M. Rossi, F. Banovic n & K. Linder n

MeSH headings : Animals; Biopsy / veterinary; Dog Diseases / diagnosis; Dog Diseases / drug therapy; Dog Diseases / pathology; Dogs; Female; Glucocorticoids / therapeutic use; Lupus Erythematosus, Cutaneous / diagnosis; Lupus Erythematosus, Cutaneous / drug therapy; Lupus Erythematosus, Cutaneous / pathology; Lupus Erythematosus, Cutaneous / veterinary; Male; Sex Factors; Skin / pathology
TL;DR: Observations support MCLE being another variant of canine CLE, a variant of cutaneous lupus erythematosus that affected mostly dogs in their mid-adulthood and there was an over-representation of females. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2015 journal article

Oral glucocorticoid pulse therapy for induction of treatment of canine pemphigus foliaceus - a comparative study

Veterinary Dermatology, 26(5), 354–e77.

By: P. Bizikova n & T. Olivry n

Contributors: P. Bizikova n & T. Olivry n

MeSH headings : Administration, Oral; Animals; Dog Diseases / drug therapy; Dogs; Drug Administration Schedule / veterinary; Glucocorticoids / administration & dosage; Glucocorticoids / therapeutic use; Pemphigus / drug therapy; Remission Induction
TL;DR: Several benefits associated with oral glucocorticoid pulse therapy are suggested, such as a higher proportion of dogs achieving complete remission (CR) during the first 3 months, a lower average maximal oral glucosuppressive dosage given between pulses and minimal adverse drug events. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: ORCID, NC State University Libraries, NC State University Libraries
Added: August 6, 2018

2015 journal article

The influence of mometasone furoate ear solution on intradermal test immediate reactions in dogs with atopic dermatitis

VETERINARY DERMATOLOGY, 26(1), 31-+.

By: K. Murphy n & T. Olivry n

Contributors: K. Marcia Murphy & T. Olivry n

MeSH headings : Administration, Topical; Alanine Transaminase / blood; Alkaline Phosphatase / blood; Animals; Anti-Inflammatory Agents / administration & dosage; Anti-Inflammatory Agents / adverse effects; Anti-Inflammatory Agents / therapeutic use; Dermatitis, Atopic / diagnosis; Dermatitis, Atopic / veterinary; Dog Diseases / diagnosis; Dogs; Ear, External; Female; Intradermal Tests / veterinary; Male; Mometasone Furoate; Otitis Externa / drug therapy; Otitis Externa / veterinary; Pregnadienediols / administration & dosage; Pregnadienediols / adverse effects; Pregnadienediols / therapeutic use
TL;DR: Results from this study show that a withdrawal period of ≤7 days is possible before performing IDT in atopic dogs with active otitis externa treated with ≤14 days of MF. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2015 journal article

Treatment of canine atopic dermatitis: 2015 updated guidelines from the International Committee on Allergic Diseases of Animals (ICADA)

BMC VETERINARY RESEARCH, 11(1).

By: T. Olivry n, D. DeBoer*, C. Favrot*, H. Jackson, R. Mueller*, T. Nuttall*, P. Prelaud*

Contributors: T. Olivry n, D. DeBoer*, C. Favrot*, H. Jackson, R. Mueller*, T. Nuttall*, P. Prélaud*

author keywords: Atopic dermatitis; Canine; Dogs; Evidence-based medicine; Guidelines; Treatment
MeSH headings : Acute Disease; Administration, Oral; Administration, Topical; Animals; Anti-Infective Agents / therapeutic use; Anti-Inflammatory Agents / therapeutic use; Baths / veterinary; Chronic Disease; Dermatitis, Atopic / therapy; Dermatitis, Atopic / veterinary; Dermatologic Agents / therapeutic use; Dog Diseases / drug therapy; Dogs; Drug Therapy, Combination / veterinary; Glucocorticoids / therapeutic use; International Cooperation; Practice Guidelines as Topic
TL;DR: This first 5-year minor update of the international consensus guidelines for treatment of AD in dogs further establishes that the treatment of this disease is multifaceted, and that interventions should be combined for a proven (or likely) optimal benefit. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2014 article

An autoimmune subepidermal blistering skin disease in a dog? The odds are that it is not bullous pemphigoid

Olivry, T. (2014, August). VETERINARY DERMATOLOGY, Vol. 25, pp. 316–318.

By: T. Olivry n

Contributors: T. Olivry n

MeSH headings : Animals; Autoimmune Diseases / diagnosis; Autoimmune Diseases / epidemiology; Autoimmune Diseases / pathology; Autoimmune Diseases / veterinary; Dog Diseases / diagnosis; Dog Diseases / epidemiology; Dog Diseases / pathology; Dogs; Risk Factors; Skin Diseases, Vesiculobullous / diagnosis; Skin Diseases, Vesiculobullous / epidemiology; Skin Diseases, Vesiculobullous / pathology; Skin Diseases, Vesiculobullous / veterinary
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2014 chapter

Chapter 91: Treatment guidelines for canine atopic dermatitis

In J. Bonagura & D. Twedt, Current Veterinary Therapy XV (pp. 405–407). Elsevier.

By: T. Olivry & P. Prélaud

Source: NC State University Libraries
Added: September 22, 2020

2014 journal article

Ciclosporin therapy for canine generalized discoid lupus erythematosus refractory to doxycycline and niacinamide

VETERINARY DERMATOLOGY, 25(5), 483–E79.

By: F. Banovic n, T. Olivry n & K. Linder n

Contributors: F. Banovic n, T. Olivry n & K. Linder n

MeSH headings : Animals; Anti-Bacterial Agents / administration & dosage; Anti-Bacterial Agents / therapeutic use; Antifungal Agents / administration & dosage; Antifungal Agents / therapeutic use; Cyclosporine / administration & dosage; Cyclosporine / therapeutic use; Dermatologic Agents / administration & dosage; Dermatologic Agents / therapeutic use; Dog Diseases / drug therapy; Dogs; Doxycycline / administration & dosage; Doxycycline / therapeutic use; Drug Therapy, Combination / veterinary; Ketoconazole / administration & dosage; Ketoconazole / therapeutic use; Lupus Erythematosus, Discoid / drug therapy; Lupus Erythematosus, Discoid / veterinary; Male; Niacinamide / administration & dosage; Niacinamide / therapeutic use; Treatment Failure; Treatment Outcome
TL;DR: The combination of ciclosporin and ketoconazole appeared effective to induce and maintain lesion remission in this dog with generalized DLE. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2014 journal article

Clinical and Microscopic Characteristics of Canine Toxic Epidermal Necrolysis

Veterinary Pathology, 52(2), 321–330.

By: F. Banovic n, T. Olivry n, L. Bazzle n, J. Tobias n, B. Atlee, S. Zabel*, N. Hensel*, K. Linder n

Contributors: F. Banovic n, T. Olivry n, L. Bazzle n, J. Tobias n, B. Atlee, S. Zabel*, N. Hensel*, K. Linder n

author keywords: ALDEN; Canis familiaris; carprofen; drug reaction; erythema multiforme; skin; toxic epidermal necrolysis
MeSH headings : Animals; Apoptosis; Biopsy / veterinary; Disease Progression; Dog Diseases / pathology; Dogs; Drug-Related Side Effects and Adverse Reactions / veterinary; Epidermis / pathology; Female; Necrosis / veterinary; Stevens-Johnson Syndrome / pathology; Stevens-Johnson Syndrome / veterinary
TL;DR: Clinically, irregular erythematous and purpuric macules evolved into widespread and severely painful erosions, and the sequence of changes points to lymphocyte-mediated keratinocyte apoptosis as an early step in lesion development with subsequent variation in progression to coagulation necrosis among patients. (via Semantic Scholar)
Sources: ORCID, Crossref
Added: July 21, 2019

2014 journal article

Fipronil-amitraz-S-methoprene-triggered pemphigus foliaceus in 21 dogs: clinical, histological and immunological characteristics

Veterinary Dermatology, 25(2), 103–e30.

By: P. Bizikova n, K. Linder n & T. Olivry n

Contributors: P. Bizikova n, K. Linder n & T. Olivry n

MeSH headings : Animals; Dog Diseases / chemically induced; Dog Diseases / immunology; Dog Diseases / pathology; Dogs; Drug Combinations; Female; Insecticides / administration & dosage; Insecticides / adverse effects; Insecticides / therapeutic use; Male; Methoprene / administration & dosage; Methoprene / adverse effects; Methoprene / therapeutic use; Pemphigus / chemically induced; Pemphigus / immunology; Pemphigus / pathology; Pemphigus / veterinary; Pyrazoles / administration & dosage; Pyrazoles / adverse effects; Pyrazoles / therapeutic use; Toluidines / administration & dosage; Toluidines / adverse effects; Toluidines / therapeutic use
TL;DR: This new topical ectoparasiticide containing fipronil, amitraz and S-methoprene is capable of triggering the development of an acantholytic pustular dermatosis that is a clinical, histological and immunological close match for Promeris-triggered PF and naturally occurring autoimmune PF in dogs. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: ORCID, NC State University Libraries, Crossref, NC State University Libraries
Added: August 6, 2018

2014 article

Pathology in Practice

Banovic, F., Olivry, T., Linder, K. E., & Tobias, J. R. (2014, December 1). JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, Vol. 245, pp. 1237–1239.

By: F. Banovic n, T. Olivry*, K. Linder* & J. Tobias*

MeSH headings : Animals; Anti-Inflammatory Agents / administration & dosage; Anti-Inflammatory Agents / therapeutic use; Cyclosporine / administration & dosage; Cyclosporine / adverse effects; Cyclosporine / therapeutic use; Dog Diseases / pathology; Dogs; Drug Eruptions / pathology; Drug Eruptions / veterinary; Drug Therapy, Combination; Female; Immunosuppressive Agents / administration & dosage; Immunosuppressive Agents / adverse effects; Immunosuppressive Agents / therapeutic use; Lupus Erythematosus, Cutaneous / drug therapy; Lupus Erythematosus, Cutaneous / pathology; Lupus Erythematosus, Cutaneous / veterinary; Prednisolone / administration & dosage; Prednisolone / therapeutic use
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2014 journal article

Pathology in practice

Journal of the American Veterinary Medical Association, 245(11), 1237–1239. http://www.scopus.com/inward/record.url?eid=2-s2.0-84922952862&partnerID=MN8TOARS

By: F. Banovic, T. Olivry, K. Linder & J. Tobias

Contributors: F. Banovic, T. Olivry, K. Linder & J. Tobias

Source: ORCID
Added: August 29, 2019

2014 journal article

Serum autoantibody profiles of IgA, IgE and IgM in canine pemphigus foliaceus

VETERINARY DERMATOLOGY, 25(5), 471–E75.

By: P. Bizikova n, T. Olivry n, L. Mamo n & S. Dunston n

Contributors: P. Bizikova n, T. Olivry n, L. Mamo n & S. Dunston n

MeSH headings : Animals; Autoantibodies / blood; Autoantibodies / immunology; Desmocollins / immunology; Desmoglein 1 / immunology; Dog Diseases / blood; Dog Diseases / immunology; Dogs; Fluorescent Antibody Technique, Indirect / veterinary; Immunoglobulin A / blood; Immunoglobulin A / immunology; Immunoglobulin E / blood; Immunoglobulin E / immunology; Immunoglobulin M / blood; Immunoglobulin M / immunology; Keratinocytes / immunology; Pemphigus / blood; Pemphigus / immunology; Pemphigus / veterinary
TL;DR: It appears that canine PF is aetiologically and immunologically similar to that of the classic human PF, in which the IgG autoantibody response is also the predominant type. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2014 journal article

The Skin Microbiome in Healthy and Allergic Dogs

PLOS ONE, 9(1).

By: A. Rodrigues Hoffmann*, A. Patterson*, A. Diesel*, S. Lawhon*, H. Ly*, C. Stephenson*, J. Mansell*, J. Steiner* ...

MeSH headings : Animals; Biodiversity; Dog Diseases / microbiology; Dog Diseases / pathology; Dogs; Female; Health; Humans; Hypersensitivity / microbiology; Hypersensitivity / pathology; Hypersensitivity / veterinary; Male; Microbiota; Nasal Mucosa / microbiology; Phylogeny; Principal Component Analysis; RNA, Ribosomal, 16S / genetics; Skin / microbiology
TL;DR: The study demonstrates that the skin of dogs is inhabited by much more rich and diverse microbial communities than previously thought using culture-based methods. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2014 journal article

The skin microbiome in healthy and allergic dogs

PLoS ONE, 9(1).

By: A. Hoffmann, A. Patterson, A. Diesel, S. Lawhon, H. Ly, C. Stephenson, J. Mansell, J. Steiner ...

Contributors: A. Hoffmann, A. Patterson, A. Diesel, S. Lawhon, H. Ly, C. Stephenson, J. Mansell, J. Steiner ...

Source: ORCID
Added: August 29, 2019

2014 journal article

Validation of the Canine Atopic Dermatitis Extent and Severity Index (CADESI)-4, a simplified severity scale for assessing skin lesions of atopic dermatitis in dogs

VETERINARY DERMATOLOGY, 25(2), 77-+.

By: T. Olivry n, M. Saridomichelakis*, T. Nuttall*, E. Bensignor*, C. Griffin & P. Hill*

Contributors: T. Olivry n, M. Saridomichelakis*, T. Nuttall*, E. Bensignor*, C. Griffin & P. Hill*

MeSH headings : Animals; Dermatitis, Atopic / pathology; Dermatitis, Atopic / veterinary; Dog Diseases / classification; Dog Diseases / pathology; Dogs; Pain Measurement / classification; Pain Measurement / veterinary; Pruritus / classification; Pruritus / veterinary; Reproducibility of Results; Severity of Illness Index
TL;DR: A fourth version of the Canine Atopic Dermatitis Extent and Severity Index (CADESI) that is simpler to use and quicker to administer than its previous version is developed and validated. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2013 journal article

A pilot study of the validation of percutaneous testing in cats

Veterinary Dermatology, 24(5), 488–e115.

By: M. Rossi n, L. Messinger, T. Olivry n & R. Hoontrakoon

Contributors: M. Rossi n, L. Messinger, T. Olivry n & R. Hoontrakoon

MeSH headings : Allergens / immunology; Animals; Cat Diseases / diagnosis; Cat Diseases / immunology; Cats; Dermatitis, Atopic / diagnosis; Dermatitis, Atopic / immunology; Dermatitis, Atopic / veterinary; Female; Histamine / immunology; Hypersensitivity / diagnosis; Hypersensitivity / veterinary; Intradermal Tests / veterinary; Male; Pilot Projects; Sensitivity and Specificity; Skin / drug effects; Skin / immunology; Skin Tests / methods; Skin Tests / veterinary
TL;DR: Percutaneous reactions to histamine were more well demarcated and easier to read than intradermal injection reactions, and warrant further studies of percutaneous allergen testing in cats with hypersensitivity dermatitis. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, Crossref, NC State University Libraries
Added: August 6, 2018

2013 journal article

A systematic review of randomized controlled trials for prevention or treatment of atopic dermatitis in dogs: 2008-2011 update

VETERINARY DERMATOLOGY, 24(1), 97-+.

By: T. Olivry n & P. Bizikova n

Contributors: T. Olivry n & P. Bizikova n

MeSH headings : Animals; Anti-Inflammatory Agents / therapeutic use; Dermatitis, Atopic / therapy; Dermatitis, Atopic / veterinary; Dog Diseases / prevention & control; Dog Diseases / therapy; Dogs; Immunosuppressive Agents / therapeutic use; Randomized Controlled Trials as Topic
TL;DR: Topical or oral glucocorticoids and oral ciclosporin remain the interventions with highest evidence for efficacy and relative safety for treatment of canine AD. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2013 journal article

Cowhage can induce itch in the atopic dog

EXPERIMENTAL DERMATOLOGY, 22(6), 435–437.

By: T. Olivry n, P. Bizikova n, J. Paps n, S. Dunston n, E. Lerner* & G. Yosipovitch*

Contributors: T. Olivry n, P. Bizikova n, J. Paps n, S. Dunston n, E. Lerner* & G. Yosipovitch*

author keywords: canine; dog; itch; model; pruritus
MeSH headings : Animals; Dermatitis, Atopic / etiology; Dermatitis, Atopic / physiopathology; Dogs; Hot Temperature; Inflammation; Mucuna / metabolism; Peptide Hydrolases / chemistry; Protein Denaturation; Pruritus / etiology; Pruritus / physiopathology; Random Allocation; Recombinant Proteins / chemistry; Skin / drug effects; Skin Tests / methods
TL;DR: Cowhage spicules, protein‐rich extracts and mucunain can all inducePruritus and inflammation in dogs as in other species, but the inconsistency of provocation is currently a limitation of this challenge type for future studies of pruritus in dogs. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2013 review

Evidence-based guidelines for anti-allergic drug withdrawal times before allergen-specific intradermal and IgE serological tests in dogs

[Review of ]. VETERINARY DERMATOLOGY, 24(2).

By: T. Olivry n & M. Saridomichelakis*

Contributors: T. Olivry n & M. Saridomichelakis*

MeSH headings : Animals; Anti-Allergic Agents / pharmacokinetics; Anti-Allergic Agents / pharmacology; Dog Diseases / blood; Dog Diseases / diagnosis; Dog Diseases / drug therapy; Dogs; Evidence-Based Medicine / standards; Immunoglobulin E / blood; Intradermal Tests / veterinary; Serologic Tests / veterinary; Time Factors
TL;DR: Suggestions for anti-allergic drug withdrawal times before allergen-specific intradermal tests and ASIS tests based on the existing evidence at the end of 2011 are presented. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2013 journal article

Pemphigus vulgaris in a Welsh pony stallion: case report and demonstration of antidesmoglein autoantibodies

VETERINARY DERMATOLOGY, 24(2), 269–E60.

By: L. Winfield*, S. White*, V. Affolter*, A. Renier*, D. Dawson*, T. Olivry n, C. Outerbridge*, Y. Wang* ...

Contributors: L. Winfield*, S. White*, V. Affolter*, A. Renier*, D. Dawson*, T. Olivry n, C. Outerbridge*, Y. Wang*, K. Iyori*, K. Nishifuji*

MeSH headings : Animals; Autoantibodies / blood; Desmogleins / immunology; Horse Diseases / immunology; Horse Diseases / metabolism; Horse Diseases / pathology; Horses; Immunoglobulin G / blood; Male; Pemphigus / blood; Pemphigus / immunology; Pemphigus / pathology; Pemphigus / veterinary
TL;DR: A case that was substantiated by the demonstration of anti-Dsg3 IgG is described, likely to carry a poor prognosis and if there is no response to treatment, humane euthanasia is warranted. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2013 journal article

Putative paraneoplastic pemphigus and myasthenia gravis in a cat with a lymphocytic thymoma

VETERINARY DERMATOLOGY, 24(6), 646-+.

By: P. Hill*, P. Brain, D. Collins, S. Fearnside & T. Olivry n

Contributors: P. Hill*, P. Brain, D. Collins, S. Fearnside & T. Olivry n

MeSH headings : Animals; Cat Diseases / drug therapy; Cat Diseases / pathology; Cats; Female; Lymphoma / complications; Lymphoma / pathology; Lymphoma / veterinary; Myasthenia Gravis / complications; Myasthenia Gravis / drug therapy; Myasthenia Gravis / veterinary; Pemphigus / etiology; Pemphigus / veterinary; Prednisolone / therapeutic use; Pyridostigmine Bromide / therapeutic use; Thymoma / complications; Thymoma / pathology; Thymoma / veterinary
TL;DR: Clinical, microscopic and immunological findings were consistent with a diagnosis of Paraneoplastic pemphigus, with thymoma being the suspected cause in this cat. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2012 journal article

Bilaterally Symmetrical Alopecia With Reticulated Hyperpigmentation

Veterinary Pathology, 50(4), 682–685.

By: T. Olivry n & K. Linder n

Contributors: T. Olivry n & K. Linder n

author keywords: alopecia; autoimmunity; dog diseases; hair follicle; lupus
MeSH headings : Alopecia / immunology; Alopecia / pathology; Alopecia / veterinary; Animals; Autoimmunity; Biopsy; Dog Diseases / immunology; Dog Diseases / pathology; Dogs; Folliculitis / immunology; Folliculitis / pathology; Folliculitis / veterinary; Hair Follicle / pathology; Hyperpigmentation / immunology; Hyperpigmentation / pathology; Hyperpigmentation / veterinary; Lupus Erythematosus, Discoid / immunology; Lupus Erythematosus, Discoid / pathology; Lupus Erythematosus, Discoid / veterinary; Lupus Erythematosus, Systemic / immunology; Lupus Erythematosus, Systemic / pathology; Lupus Erythematosus, Systemic / veterinary; Male; Skin / pathology
TL;DR: An adult castrated male Doberman Pinscher was presented with a 6-month history of well-demarcated alopecic patches with reticulated hyperpigmentation and fine peripheral scaling, eventually associated with the development of systemic lupus erythematosus. (via Semantic Scholar)
Sources: ORCID, Crossref
Added: July 21, 2019

2012 journal article

Characteristics of Malassezia pachydermatis Isolated from Dogs and Antifungal Effect of Essential Oils

Journal of Veterinary Clinics, 29(2), 141–147. http://www.scopus.com/inward/record.url?eid=2-s2.0-84862540745&partnerID=MN8TOARS

By: J. Kim, T. Olivry & W. Son

Contributors: J. Kim, T. Olivry & W. Son

Source: ORCID
Added: August 29, 2019

2012 journal article

Cloning and establishment of canine desmocollin-1 as a major autoantigen in canine pemphigus foliaceus

VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 149(3-4), 197–207.

By: P. Bizikova n, G. Dean*, T. Hashimoto* & T. Olivry n

Contributors: P. Bizikova n, G. Dean*, T. Hashimoto* & T. Olivry n

author keywords: Autoimmunity; Blistering disease; Desmosome; Desmoglein; DSG1
MeSH headings : Amino Acid Sequence; Animals; Autoantigens / immunology; Base Sequence; Blotting, Western / veterinary; Cloning, Molecular; Desmocollins / genetics; Desmocollins / immunology; Dog Diseases / blood; Dog Diseases / immunology; Dogs; Fluorescent Antibody Technique, Indirect / veterinary; Immunoglobulin G / blood; Immunoglobulin G / immunology; Molecular Sequence Data; Pemphigus / blood; Pemphigus / immunology; Pemphigus / veterinary; RNA, Messenger / chemistry; RNA, Messenger / genetics; Reverse Transcriptase Polymerase Chain Reaction / veterinary; Sequence Alignment; Sequence Analysis, DNA
TL;DR: Findings suggest that DSC1 is a major autoantigen in canine PF (cPF), as proposed in a recent immunomapping study. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2012 journal article

Deficient Plakophilin-1 Expression Due to a Mutation in PKP1 Causes Ectodermal Dysplasia-Skin Fragility Syndrome in Chesapeake Bay Retriever Dogs

PLoS ONE, 7(2), e32072.

By: T. Olivry n, K. Linder n, P. Wang*, P. Bizikova n, J. Bernstein, S. Dunston n, J. Paps n, M. Casal*

Contributors: T. Olivry n, K. Linder n, P. Wang*, P. Bizikova n, J. Bernstein, S. Dunston n, J. Paps n, M. Casal*

Ed(s): J. Brandner

MeSH headings : Animals; DNA Primers / genetics; Desmosomes / metabolism; Disease Models, Animal; Dogs; Ectodermal Dysplasia / genetics; Gene Expression Regulation; Keratins / chemistry; Microscopy, Electron / methods; Microscopy, Electron, Transmission / methods; Mutation; Phenotype; Plakophilins / biosynthesis; Plakophilins / genetics; Sequence Analysis, DNA / methods; Skin / pathology; Skin Diseases / genetics; Skin Diseases / metabolism
TL;DR: The clinical and pathological findings, along with the PKP1 mutation, were consistent with the diagnosis of ectodermal dysplasia-skin fragility syndrome with plakophilin-1 deficiency, a novel congenital acantholytic dermatosis that developed in Chesapeake Bay retriever dogs. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: ORCID, NC State University Libraries, Crossref, NC State University Libraries
Added: August 6, 2018

2012 journal article

Dermatophagoides farinae house dust mite allergen challenges reduce stratum corneum ceramides in an experimental dog model of acute atopic dermatitis

Veterinary Dermatology, 23(6), 497–e97.

By: J. Stahl*, J. Paps n, W. Bäumer* & T. Olivry n

Contributors: J. Stahl*, J. Paps n, W. Bäumer* & T. Olivry n

MeSH headings : Animals; Antigens, Dermatophagoides / toxicity; Ceramides / chemistry; Ceramides / metabolism; Dermatitis, Atopic / immunology; Dermatitis, Atopic / metabolism; Dermatitis, Atopic / pathology; Dermatitis, Atopic / veterinary; Dog Diseases / immunology; Dog Diseases / metabolism; Dog Diseases / pathology; Dogs; Epidermis / metabolism; Fatty Acids, Nonesterified / metabolism
TL;DR: The findings suggest that the allergic reactions caused by Df-HDM allergens lead to a selective reduction of SC ceramides, not only at sites of inflammation but also at sites away from those of allergen application. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: NC State University Libraries, ORCID, Crossref, NC State University Libraries
Added: August 6, 2018

2012 journal article

Establishment of diagnostic criteria for feline nonflea-induced hypersensitivity dermatitis

Veterinary Dermatology, 23(1).

By: C. Favrot*, J. Steffan*, W. Seewald*, S. Hobi*, M. Linek, G. Marignac*, T. Olivry*, L. Beco* ...

Contributors: C. Favrot*, J. Steffan*, W. Seewald*, S. Hobi*, M. Linek, G. Marignac*, T. Olivry*, L. Beco* ...

MeSH headings : Animals; Cat Diseases / diagnosis; Cat Diseases / immunology; Cats; Dermatitis, Allergic Contact / diagnosis; Dermatitis, Allergic Contact / veterinary; Female; Male; Practice Guidelines as Topic / standards; Prospective Studies; Pruritus / etiology; Pruritus / veterinary; Retrospective Studies; Siphonaptera
TL;DR: Criteria sets were associated with good sensitivity and specificity and may be useful for homogeneity of enrolment in clinical trials and to evaluate the probability of diagnosis of NFHD in clinical practice, but were not useful to differentiate cats with NFHD from those with food HD. (via Semantic Scholar)
Source: ORCID
Added: August 29, 2019

2012 journal article

Immunohistochemical and immunopathologic characterization of superficial stromal immune-mediated keratitis in horses

American Journal of Veterinary Research, 73(7), 1067–1073.

By: D. Pate n, A. Clode n, T. Olivry n, J. Cullen n, J. Salmon n & B. Gilger n

Contributors: D. Pate n, A. Clode n, T. Olivry n, J. Cullen n, J. Salmon n & B. Gilger n

TL;DR: Pathogenesis of superficial stromal immune-mediated keratitis included cell-mediated inflammation governed by both cytotoxic and helper T cells and local immunoglobulins were present in affected corneas; however, corneal-binding immunoglolins were not detected in the serum or AH from horses with IMMK. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2012 journal article

Responsiveness and validity of the SCORFAD, an extent and severity scale for feline hypersensitivity dermatitis

Veterinary Dermatology, 23(5).

By: J. Steffan*, T. Olivry n, S. Forster* & W. Seewald*

Contributors: J. Steffan*, T. Olivry n, S. Forster* & W. Seewald*

MeSH headings : Animals; Cat Diseases / drug therapy; Cat Diseases / pathology; Cats; Cyclosporine / therapeutic use; Dermatitis, Atopic / drug therapy; Dermatitis, Atopic / pathology; Dermatitis, Atopic / veterinary; Immunosuppressive Agents / therapeutic use; Reproducibility of Results; Sensitivity and Specificity
TL;DR: The SCORFAD scale is proposed for use as a validated tool for the assessment of disease severity and response to therapeutic interventions in clinical trials for feline HD. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: ORCID
Added: August 29, 2019

2012 journal article

Successful treatment of a novel generalized variant of canine discoid lupus erythematosus with oral hydroxychloroquine

VETERINARY DERMATOLOGY, 23(1), 65–E16.

By: U. Oberkirchner, K. Linder n & T. Olivry n

Contributors: U. Oberkirchner, K. Linder n & T. Olivry n

MeSH headings : Administration, Oral; Animals; Antirheumatic Agents / therapeutic use; Dog Diseases / drug therapy; Dog Diseases / pathology; Dogs; Female; Hydroxychloroquine / therapeutic use; Lupus Erythematosus, Discoid / drug therapy; Lupus Erythematosus, Discoid / pathology; Lupus Erythematosus, Discoid / veterinary; Treatment Outcome
TL;DR: A generalized variant of canine DLE successfully treated with the antimalarial immunomodulator hydroxychloroquine (HCQ) mirrored the generalized discoid variant of chronic cutaneous lupus erythematosus of humans, and the apparent benefit of HCQ, its safety and low cost warrant future investigations of its use for treatment of canine cutaneouslupus variants. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2012 journal article

Validation of a novel epicutaneous delivery system for patch testing of house dust mite-hypersensitive dogs

Veterinary Dermatology, 23(6).

By: T. Olivry*, K. Linder n, J. Paps*, P. Bizikova*, S. Dunston*, N. Donne*, L. Mondoulet*

Contributors: T. Olivry*, K. Linder n, J. Paps*, P. Bizikova*, S. Dunston*, N. Donne*, L. Mondoulet*

MeSH headings : Animals; Dermatitis, Atopic / diagnosis; Dermatitis, Atopic / veterinary; Dermatophagoides farinae / immunology; Dog Diseases / diagnosis; Dog Diseases / immunology; Dogs; Patch Tests / veterinary
TL;DR: In mite-allergic dogs, Viaskin epicutaneous delivery systems appear to induce stronger allergen-specific inflammation than currently used Finn chamber patch tests. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: ORCID, NC State University Libraries, NC State University Libraries
Added: August 6, 2018

2012 book

What can dogs bring to atopic dermatitis research?

In Chemical Immunology and Allergy (Vol. 96, pp. 61–72).

By: T. Olivry n

Contributors: T. Olivry n

MeSH headings : Allergens / immunology; Allergens / metabolism; Animals; Antibodies / immunology; Antibodies / metabolism; Dermatitis, Atopic / immunology; Dermatitis, Atopic / pathology; Dermatitis, Atopic / therapy; Disease Models, Animal; Dog Diseases / immunology; Dog Diseases / pathology; Dog Diseases / therapy; Dogs; Male; Phenotype
TL;DR: These experimental canine AD models have proven their utility to test the efficacy of novel treatment modalities in a preclinical setting and can provide researchers with a unique model to investigate genetic, epidemiological, mechanistic or treatment facets of the human disease. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: NC State University Libraries, ORCID, NC State University Libraries
Added: August 6, 2018

2011 journal article

Ask the expert: canine atopic dermatitis

NAVC Clinician’s Brief, 35–37.

By: K. Moriello & T. Olivry

Source: NC State University Libraries
Added: February 13, 2021

2011 journal article

Clinical characteristics and causes of pruritus in cats: a multicentre study on feline hypersensitivity-associated dermatoses

VETERINARY DERMATOLOGY, 22(5), 406–413.

By: S. Hobi*, M. Linek, G. Marignac*, T. Olivry n, L. Beco*, C. Nett, J. Fontaine, P. Roosje* ...

Contributors: S. Hobi*, M. Linek, G. Marignac*, T. Olivry n, L. Beco*, C. Nett, J. Fontaine, P. Roosje* ...

MeSH headings : Animals; Cat Diseases / etiology; Cats; Dermatitis, Allergic Contact / etiology; Dermatitis, Allergic Contact / veterinary; Ectoparasitic Infestations / complications; Ectoparasitic Infestations / veterinary; Female; Food Hypersensitivity / veterinary; Male; Pruritus / etiology; Pruritus / veterinary; Siphonaptera
TL;DR: Most cats with nonflea HD exhibited signs compatible with one or more of the four typical lesional patterns, but none of these patterns was found to be pathognomonic for any specific diagnosis. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2011 review

Current evidence of skin barrier dysfunction in human and canine atopic dermatitis

[Review of ]. VETERINARY DERMATOLOGY, 22(3), 239–248.

By: R. Marsella*, T. Olivry* & D. Carlotti

Contributors: R. Marsella*, T. Olivry* & D. Carlotti

MeSH headings : Animals; Dermatitis, Atopic / immunology; Dermatitis, Atopic / metabolism; Dermatitis, Atopic / physiopathology; Dermatitis, Atopic / veterinary; Dog Diseases / immunology; Dog Diseases / metabolism; Dog Diseases / physiopathology; Dogs; Filaggrin Proteins; Humans
TL;DR: Evidence is rapidly building to support a role for skin barrier dysfunction in canine AD, which shares many clinical and immunological similarities with its human counterpart. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2011 journal article

Establishment of a quantitative ELISA for the measurement of allergen-specific IgE in dogs using anti-IgE antibody cross-reactive to mouse and dog IgE

VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 139(2-4), 99–106.

By: T. Okayama, Y. Matsuno, N. Yasuda, T. Tsukui*, Y. Suzuta*, M. Koyanagi*, M. Sakaguchi*, Y. Ishii* ...

Contributors: T. Okayama, Y. Matsuno, N. Yasuda, T. Tsukui*, Y. Suzuta*, M. Koyanagi*, M. Sakaguchi*, Y. Ishii*, T. Olivry n, K. Masuda

author keywords: Dogs; IgE; Canine atopic dermatitis; ELISA; Allergy
MeSH headings : Allergens / immunology; Animals; Antibodies, Anti-Idiotypic / immunology; Antibody Specificity / immunology; Dogs; Enzyme-Linked Immunosorbent Assay / veterinary; Female; Immunoglobulin E / immunology; Mice; Rats; Rats, Wistar
TL;DR: A quantitative ELISA that could measure canine IgE recognizing Cry j 1, one of the major allergens of Japanese cedar pollen, demonstrated that the ELISA utilizing CRE-DM was a specific, reliable and robust new laboratory test that could quantify absolute amount of antigen-specific IgE in canine serum. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2011 personal communication

Evaluation of the agreement between allergen-specific intradermal or IgE serological tests and a point-of-care immunodot assay in dogs with atopic dermatitis

Olivry, T., & Paps, J. (2011, June).

By: T. Olivry n & J. Paps n

Contributors: T. Olivry n & J. Paps n

MeSH headings : Allergens / immunology; Animals; Dermatitis, Atopic / blood; Dermatitis, Atopic / diagnosis; Dermatitis, Atopic / immunology; Dermatitis, Atopic / veterinary; Dog Diseases / blood; Dog Diseases / diagnosis; Dog Diseases / immunology; Dogs; Immunoblotting / methods; Immunoblotting / veterinary; Immunoglobulin E / blood; Intradermal Tests / veterinary; Predictive Value of Tests; Serologic Tests / veterinary
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2011 journal article

Genome-wide linkage study of atopic dermatitis in West Highland White Terriers

BMC Genetics, 12(1), 37.

By: C. Salzmann n, T. Olivry n, D. Nielsen n, J. Paps n, T. Harris n & N. Olby n

Contributors: C. Salzmann n, T. Olivry n, D. Nielsen n, J. Paps n, T. Harris n & N. Olby n

MeSH headings : Animals; Chromosome Mapping; Dermatitis, Atopic / genetics; Dermatitis, Atopic / veterinary; Dog Diseases / genetics; Dogs; Genetic Linkage; Genotype
TL;DR: The study was unable to detect any chromosomal regions significantly linked to canine AD, and a genome-wide SNP association study in a larger cohort of WHWTs may prove more successful by providing higher density coverage and higher statistical power. (via Semantic Scholar)
Sources: ORCID, NC State University Libraries, Crossref, NC State University Libraries
Added: August 6, 2018

2011 journal article

Immunomapping of desmosomal and nondesmosomal adhesion molecules in healthy canine footpad, haired skin and buccal mucosal epithelia: comparison with canine pemphigus foliaceus serum immunoglobulin G staining patterns

VETERINARY DERMATOLOGY, 22(2), 132–142.

By: P. Bizikova n, K. Linder n & T. Olivry n

Contributors: P. Bizikova n, K. Linder n & T. Olivry n

MeSH headings : Animals; Cell Adhesion Molecules / analysis; Desmosomal Cadherins / analysis; Dog Diseases / blood; Dog Diseases / immunology; Dog Diseases / metabolism; Dogs; Fluorescent Antibody Technique, Indirect / veterinary; Foot; Immunoglobulin G / blood; Mouth Mucosa / immunology; Mouth Mucosa / metabolism; Pemphigus / blood; Pemphigus / immunology; Pemphigus / metabolism; Pemphigus / veterinary; Skin / immunology; Skin / metabolism
TL;DR: The immunological heterogeneity of cPF immunoglobulin G autoantibodies is confirmed and the major indirect immunofluorescence staining pattern and the inability of most cPF sera to label the buccal mucosa closely matched that of desmocollin-1. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2011 journal article

Is the skin barrier abnormal in dogs with atopic dermatitis?

Veterinary Immunology and Immunopathology, 144(1-2), 11–16.

By: T. Olivry n

Contributors: T. Olivry n

author keywords: Allergy; Atopy; Canine; Skin; Stratum corneum
MeSH headings : Animals; Dermatitis, Atopic / drug therapy; Dermatitis, Atopic / immunology; Dermatitis, Atopic / physiopathology; Dermatitis, Atopic / veterinary; Dermatologic Agents / therapeutic use; Dog Diseases / drug therapy; Dog Diseases / immunology; Dog Diseases / physiopathology; Dogs; Filaggrin Proteins; Lipids / physiology; Skin / immunology; Skin / physiopathology; Water Loss, Insensible
TL;DR: Whether or not a therapeutic intervention aimed at restoring a dysfunctional skin barrier is of any clinical benefit to atopic dogs has not yet been proven unequivocally. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Source: ORCID
Added: August 29, 2019

2011 journal article

Lack of preventing effect of systemically and topically administered histamine H-1 or H-4 receptor antagonists in a dog model of acute atopic dermatitis

EXPERIMENTAL DERMATOLOGY, 20(7), 577–581.

By: W. Baeumer, J. Stahl*, K. Sander*, L. Petersen*, J. Paps n, H. Stark*, M. Kietzmann*, T. Olivry n

Contributors: W. Bäumer n, J. Stahl*, K. Sander*, L. Petersen*, J. Paps n, H. Stark*, M. Kietzmann*, T. Olivry n

author keywords: canine atopic dermatitis; histamine H4 receptor; microdialysis; JNJ28307474; JNJ7777120
MeSH headings : Aging / physiology; Animals; Antigens, Dermatophagoides / administration & dosage; Antigens, Dermatophagoides / immunology; Antigens, Dermatophagoides / metabolism; Cetirizine / administration & dosage; Cetirizine / therapeutic use; Dermatitis, Atopic / chemically induced; Dermatitis, Atopic / complications; Dermatitis, Atopic / drug therapy; Dermatitis, Atopic / immunology; Dermatitis, Atopic / pathology; Dermatophagoides farinae / immunology; Disease Models, Animal; Dogs; Erythema / etiology; Erythema / pathology; Erythema / prevention & control; Female; Histamine / metabolism; Histamine Antagonists / administration & dosage; Histamine Antagonists / metabolism; Histamine Antagonists / therapeutic use; Histamine H1 Antagonists / administration & dosage; Histamine H1 Antagonists / therapeutic use; Hydroxyzine / administration & dosage; Hydroxyzine / therapeutic use; Indoles / administration & dosage; Indoles / metabolism; Indoles / therapeutic use; Male; Permeability; Piperazines / administration & dosage; Piperazines / metabolism; Piperazines / therapeutic use; Skin / metabolism; Skin / pathology; Skin Absorption / physiology; Triamcinolone / administration & dosage; Triamcinolone / therapeutic use
TL;DR: The preventive administration of H1R or H4R antagonists has no impact on the development of acute skin lesions in this experimental canine atopic dermatitis model and determined that only during the initiation increased concentrations of histamine were detected. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2011 journal article

Metaflumizone-amitraz (Promeris)-associated pustular acantholytic dermatitis in 22 dogs: evidence suggests contact drug-triggered pemphigus foliaceus

VETERINARY DERMATOLOGY, 22(5), 436–448.

By: U. Oberkirchner, K. Linder n, S. Dunston*, P. Bizikova* & T. Olivry n

Contributors: U. Oberkirchner, K. Linder n, S. Dunston*, P. Bizikova* & T. Olivry n

MeSH headings : Administration, Topical; Animals; Apoptosis / drug effects; Apoptosis / physiology; Caspase 3 / metabolism; Dog Diseases / chemically induced; Dog Diseases / drug therapy; Dog Diseases / immunology; Dog Diseases / pathology; Dogs; Female; Immunosuppressive Agents / administration & dosage; Immunosuppressive Agents / therapeutic use; Insecticides / administration & dosage; Insecticides / adverse effects; Keratinocytes / enzymology; Male; Pemphigus / chemically induced; Pemphigus / drug therapy; Pemphigus / veterinary; Semicarbazones / administration & dosage; Semicarbazones / adverse effects; Skin / pathology; Toluidines / administration & dosage; Toluidines / adverse effects
TL;DR: PD has the potential of triggering a variant of PF that resembles spontaneously occurring autoimmune PF at clinical, morphological, immunological and treatment outcome levels. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2011 journal article

Recognizing and treating Promeris-triggered pemphigus foliaceus in dogs

Veterinary Medicine, 106, 284–293.

By: U. Oberkirchner, K. Linder & T. Olivry

Source: NC State University Libraries
Added: September 22, 2020

2011 journal article