Anastasios A Tsiatis
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Works (99)
Updated: July 26th, 2023 19:25
2022 article
Group sequential methods for interim monitoring of randomized clinical trials with time-lagged outcome
Tsiatis, A. A., & Davidian, M. (2022, September 18). STATISTICS IN MEDICINE, Vol. 9.
author keywords: augmented inverse probability weighting; early stopping; influence function; proportion of information
MeSH headings : Humans; Randomized Controlled Trials as Topic; Odds Ratio; Research Design
onlinelibrary.wiley.com (publisher PDF)
Sources: Web Of Science, ORCID
Added: October 3, 2022
2021 review
Data and Safety Monitoring of COVID-19 Vaccine Clinical Trials
[Review of ]. JOURNAL OF INFECTIOUS DISEASES, 224(12), 1995–2000.
author keywords: SARS-CoV-2; COVID19; clinical trials; vaccines; data and safety monitoring
MeSH headings : Aged; COVID-19 / prevention & control; COVID-19 Vaccines / administration & dosage; COVID-19 Vaccines / adverse effects; COVID-19 Vaccines / immunology; Humans; SARS-CoV-2; United States; Vaccines
Source: Web Of Science
Added: February 28, 2022
2021 article
Estimating vaccine efficacy over time after a randomized study is unblinded
Tsiatis, A. A., & Davidian, M. (2021, August 13). BIOMETRICS, Vol. 8.
author keywords: crossover; inverse probability weighting; potential outcomes; randomized phase 3 vaccine trial; waning vaccine efficacy
MeSH headings : COVID-19 / prevention & control; COVID-19 Vaccines; Humans; Pandemics / prevention & control; Randomized Controlled Trials as Topic; Research Design; SARS-CoV-2; Vaccine Efficacy
Sources: Web Of Science, ORCID
Added: August 23, 2021
2021 article
Estimation of the odds ratio in a proportional odds model with censored time-lagged outcome in a randomized clinical trial
Tsiatis, A. A., Davidian, M., & Holloway, S. T. (2021, December 17). BIOMETRICS, Vol. 12.
author keywords: augmented inverse probability weighting; censored ordinal categorical outcome; covariate adjustment; COVID-19 treatment; estimating function; marked point process
Sources: Web Of Science, ORCID
Added: December 17, 2021
2021 article
Rejoinder: Estimating vaccine efficacy over time after a randomized study is unblinded
Tsiatis, A. A., & Davidian, M. (2021, August 22). BIOMETRICS, Vol. 8.
MeSH headings : Randomized Controlled Trials as Topic; Vaccine Efficacy
Sources: Web Of Science, ORCID
Added: August 30, 2021
2021 article
Risks associated with discontinuation of oral anticoagulation in newly diagnosed patients with atrial fibrillation: Results from the GARFIELD-AF Registry
Cools, F., Johnson, D., Camm, A. J., Bassand, J.-P., Verheugt, F. W. A., Yang, S., … Kakkar, A. K. (2021, July 23). JOURNAL OF THROMBOSIS AND HAEMOSTASIS, Vol. 7.
author keywords: anticoagulation; antiplatelet; atrial fibrillation; discontinuation; marginal structure models; outcomes
MeSH headings : Administration, Oral; Anticoagulants / adverse effects; Atrial Fibrillation / complications; Atrial Fibrillation / diagnosis; Atrial Fibrillation / drug therapy; Humans; Registries; Risk Factors; Stroke / diagnosis; Stroke / etiology; Stroke / prevention & control
Sources: Web Of Science, ORCID
Added: August 2, 2021
2020 review
Independent increments in group sequential tests: a review
[Review of ]. SORT-STATISTICS AND OPERATIONS RESEARCH TRANSACTIONS, 44(2), 223–264.
author keywords: Failure time data; interim analysis; longitudinal data; clinical trials; repeated significance tests; sequential methods
Source: Web Of Science
Added: January 25, 2021
2019 review
Application of a sequential multiple assignment randomized trial (SMART) design in older patients with chronic lymphocytic leukemia
[Review of ]. ANNALS OF ONCOLOGY, 30(4), 542–550.
author keywords: SMART; CLL; design strategies; adaptive interventions; randomized clinical trials
MeSH headings : Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols / therapeutic use; Data Analysis; Disease Progression; Feasibility Studies; Humans; Leukemia, Lymphocytic, Chronic, B-Cell / drug therapy; Leukemia, Lymphocytic, Chronic, B-Cell / mortality; Progression-Free Survival; Randomized Controlled Trials as Topic; Research Design; Sample Size
Sources: Web Of Science, ORCID
Added: June 17, 2019
2019 book
Dynamic Treatment Regimes
Source: Crossref
Added: January 22, 2022
2019 journal article
Identical and Nonidentical Twins: Risk and Factors Involved in Development of Islet Autoimmunity and Type 1 Diabetes
DIABETES CARE, 42(2), 192–199.
MeSH headings : Adolescent; Adult; Autoantibodies / analysis; Autoantibodies / blood; Autoimmunity / genetics; Autoimmunity / physiology; Child; Child, Preschool; Diabetes Mellitus, Type 1 / diagnosis; Diabetes Mellitus, Type 1 / epidemiology; Diabetes Mellitus, Type 1 / genetics; Diabetes Mellitus, Type 1 / prevention & control; Disease Progression; Diseases in Twins / diagnosis; Diseases in Twins / epidemiology; Diseases in Twins / genetics; Diseases in Twins / immunology; Environment; Female; Genetic Predisposition to Disease; Glutamate Decarboxylase / immunology; Humans; Insulin / metabolism; Islets of Langerhans / immunology; Male; Mass Screening / methods; Risk Factors; Seroepidemiologic Studies; Siblings; Twins / genetics; Twins, Dizygotic / genetics; Twins, Dizygotic / statistics & numerical data; Twins, Monozygotic / genetics; Twins, Monozygotic / statistics & numerical data; Young Adult
Source: Web Of Science
Added: April 20, 2020
2018 journal article
Interpretable Dynamic Treatment Regimes
JOURNAL OF THE AMERICAN STATISTICAL ASSOCIATION, 113(524), 1541–1549.
author keywords: Decision lists; Interpretability; Precision medicine; Research-practice gap; Treatment regimes; Tree-based methods
Sources: Web Of Science, ORCID
Added: February 18, 2019
2018 journal article
Modeling survival distribution as a function of time to treatment discontinuation: A dynamic treatment regime approach
BIOMETRICS, 74(3), 900–909.
author keywords: Dynamic treatment; Inverse weighting; Observational study; Survival distribution; Time-varying confounding; Treatment discontinuation
MeSH headings : Cardiovascular Diseases / therapy; Computer Simulation; Humans; Kaplan-Meier Estimate; Models, Statistical; Survival Analysis; Time-to-Treatment; Withholding Treatment / statistics & numerical data
Sources: Web Of Science, ORCID
Added: October 16, 2018
2018 journal article
Optimal two-stage dynamic treatment regimes from a classification perspective with censored survival data
BIOMETRICS, 74(4), 1180–1192.
author keywords: Doubly robust; Inverse probability weighting; Optimal treatment regime; Sequential multiple assignment randomized trial; Support vector machine; Value search
MeSH headings : Acute Disease; Algorithms; Biometry / methods; Computer Simulation; Decision Support Techniques; Humans; Leukemia; Outcome Assessment, Health Care / methods; Outcome Assessment, Health Care / standards; Randomized Controlled Trials as Topic; Support Vector Machine; Survival Analysis
Sources: Web Of Science, ORCID
Added: February 25, 2019
2017 journal article
Effect of oral insulin on prevention of diabetes in relatives of patients with type 1 diabetes a randomized clinical trial
Journal of the American Medical Association, 318(19), 1891–1902.
Source: NC State University Libraries
Added: August 6, 2018
2017 journal article
Optimal treatment regimes for survival endpoints using locally-efficient doubly-robust estimator from a classification perspective
Lifetime Data Analysis, 23(4), 585–604.
author keywords: Classification; Doubly-robust; Observational survival study; Optimal treatment regime; Value search
MeSH headings : Computer Simulation; Coronary Artery Bypass; Coronary Artery Disease / mortality; Coronary Artery Disease / therapy; Decision Making; Humans; Life Tables; Models, Statistical; Monte Carlo Method; Percutaneous Coronary Intervention; Survival Analysis; Treatment Outcome
Sources: Web Of Science, ORCID
Added: August 6, 2018
2017 journal article
Survival benefit of lung transplantation in the modern era of lung allocation
Annals of the American Thoracic Society, 14(2), 172–181.
Source: NC State University Libraries
Added: August 6, 2018
2016 journal article
A log rank type test in observational survival studies with stratified sampling
LIFETIME DATA ANALYSIS, 22(2), 280–298.
author keywords: Cox proportional hazards model; Log rank test; Observational study; Stratified sampling; Survival analysis
MeSH headings : Computer Simulation; Coronary Artery Disease / mortality; Coronary Artery Disease / therapy; Humans; Models, Statistical; Observational Studies as Topic / statistics & numerical data; Probability; Proportional Hazards Models; Sampling Studies; Survival Analysis
Source: Web Of Science
Added: August 6, 2018
2016 article
Estimating optimal treatment regimes from a classification perspective (vol 1, pg 103, 2012)
STAT, Vol. 5, pp. 278–278.
Sources: Web Of Science, ORCID
Added: August 6, 2018
2015 journal article
Estimation After a Group Sequential Trial
STATISTICS IN BIOSCIENCES, 7(2), 187–205.
author keywords: Exponential family; Frequentist inference; Generalized sample average; Joint modeling; Likelihood inference; Missing at random; Sample average
Sources: Web Of Science, ORCID
Added: August 6, 2018
2015 journal article
Using Decision Lists to Construct Interpretable and Parsimonious Treatment Regimes
BIOMETRICS, 71(4), 895–904.
author keywords: Decision lists; Exploratory analyses; Interpretability; Personalized medicine; Treatment regimes
MeSH headings : Biometry / methods; Breast Neoplasms / drug therapy; Clinical Protocols; Clinical Trials as Topic / statistics & numerical data; Computer Simulation; Decision Trees; Depression / therapy; Evidence-Based Medicine / statistics & numerical data; Female; Humans; Models, Statistical; Precision Medicine / statistics & numerical data
Sources: Web Of Science, ORCID
Added: August 6, 2018
2015 journal article
Using pilot data to size a two-arm randomized trial to find a nearly optimal personalized treatment strategy
Statistics in Medicine, 35(8), 1245–1256.
author keywords: personalized medicine; sample size calculation; treatment regimes; nonregular asymptotics; projection confidence region
MeSH headings : Biostatistics; Computer Simulation; Confidence Intervals; Data Interpretation, Statistical; Evidence-Based Practice / statistics & numerical data; Female; Fertility; Humans; Male; Models, Statistical; Pilot Projects; Precision Medicine / statistics & numerical data; Pregnancy; Randomized Controlled Trials as Topic / statistics & numerical data; Regression Analysis; Sample Size
Sources: Crossref, Web Of Science, ORCID
Added: August 6, 2018
2014 article
Combining Biomarkers to Optimize Patient Treatment Recommendations Discussions
Laber, E. B., Tsiatis, A. A., Davidian, M., & Holloway, S. T. (2014, September). BIOMETRICS, Vol. 70, pp. 707–710.
MeSH headings : Biomarkers, Tumor / blood; Biometry / methods; Breast Neoplasms / blood; Breast Neoplasms / therapy; Data Interpretation, Statistical; Female; Humans; Male; Outcome Assessment, Health Care / methods
Sources: Web Of Science, ORCID
Added: August 6, 2018
2014 journal article
On random sample size, ignorability, ancillarity, completeness, separability, and degeneracy: Sequential trials, random sample sizes, and missing data
STATISTICAL METHODS IN MEDICAL RESEARCH, 23(1), 11–41.
author keywords: Frequentist inference; generalized sample average; informative cluster size; joint modeling; likelihood inference; missing at random; random cluster size
MeSH headings : Likelihood Functions; Models, Statistical; Probability; Sample Size
Sources: Web Of Science, ORCID
Added: August 6, 2018
2014 journal article
Q- and A-Learning Methods for Estimating Optimal Dynamic Treatment Regimes
STATISTICAL SCIENCE, 29(4), 640–661.
author keywords: Advantage learning; bias-variance trade-off; model misspecification; personalized medicine; potential outcomes; sequential decision-making
Sources: Web Of Science, ORCID
Added: August 6, 2018
2013 journal article
Assessing the Causal Effect of Organ Transplantation on the Distribution of Residual Lifetime
BIOMETRICS, 69(4), 820–829.
author keywords: Causal inference; G-estimation; Lung transplantation; Martingale theory; Structural nested failure time models
MeSH headings : Adolescent; Adult; Age Distribution; Aged; Aged, 80 and over; Causality; Data Interpretation, Statistical; Humans; Internationality; Life Expectancy; Lung Diseases / mortality; Lung Diseases / surgery; Lung Transplantation / mortality; Middle Aged; Outcome Assessment, Health Care / methods; Survival Rate; Young Adult
Sources: Web Of Science, ORCID
Added: August 6, 2018
2013 journal article
Doubly-Robust Estimators of Treatment-Specific Survival Distributions in Observational Studies with Stratified Sampling
BIOMETRICS, 69(4), 830–839.
author keywords: Cox proportional hazard model; Double robustness; Observational study; Stratified sampling; Survival analysis
MeSH headings : Coronary Artery Disease / mortality; Coronary Artery Disease / surgery; Data Interpretation, Statistical; Humans; Observational Studies as Topic / methods; Outcome Assessment, Health Care / methods; Prevalence; Reproducibility of Results; Sample Size; Sensitivity and Specificity; Statistical Distributions; Survival Analysis; Treatment Outcome; United States / epidemiology
Source: Web Of Science
Added: August 6, 2018
2013 journal article
Efficient estimation of the distribution of time to composite endpoint when some endpoints are only partially observed
LIFETIME DATA ANALYSIS, 19(4), 513–546.
author keywords: Augmented inverse probability weighted estimator; Composite endpoint; Missing data; Nelson-Aalen estimator; Semi-parametric efficiency; Withdrawal
MeSH headings : Biostatistics; Clinical Trials as Topic / statistics & numerical data; Computer Simulation; Endpoint Determination / statistics & numerical data; Humans; Linear Models; Longitudinal Studies; Models, Statistical; Proportional Hazards Models; Registries / statistics & numerical data; Statistics, Nonparametric; Time Factors
Source: Web Of Science
Added: August 6, 2018
2013 journal article
Robust estimation of optimal dynamic treatment regimes for sequential treatment decisions
BIOMETRIKA, 100(3), 681–694.
author keywords: A-learning; Double robustness; Outcome regression; Propensity score; Q-learning
Sources: Web Of Science, ORCID
Added: August 6, 2018
2012 journal article
A Robust Method for Estimating Optimal Treatment Regimes
BIOMETRICS, 68(4), 1010–1018.
author keywords: Doubly robust estimator; Inverse probability weighting; Outcome regression; Personalized medicine; Potential outcomes; Propensity score
MeSH headings : Breast Neoplasms / epidemiology; Breast Neoplasms / therapy; Clinical Trials as Topic / methods; Computer Simulation; Decision Support Systems, Clinical; Female; Humans; Models, Statistical; Outcome Assessment, Health Care / methods; Prevalence; Regression Analysis; Treatment Outcome
Sources: Web Of Science, ORCID
Added: August 6, 2018
2012 journal article
Estimating optimal treatment regimes from a classification perspective
Stat, 1(1), 103–114.
author keywords: classification; doubly robust estimator; inverse probability weighting; personalized medicine; potential outcomes; propensity score
Sources: Crossref, ORCID
Added: January 23, 2020
2012 journal article
Mixed model analysis of censored longitudinal data with flexible random-effects density
BIOSTATISTICS, 13(1), 61–73.
author keywords: Censoring; HCV; HIV; Limit of quantification; Longitudinal data; Random effects
MeSH headings : Antiviral Agents / therapeutic use; Bias; Biostatistics; Data Interpretation, Statistical; Hepatitis C / drug therapy; Hepatitis C / virology; Humans; Interferon-alpha / therapeutic use; Linear Models; Longitudinal Studies; Models, Statistical; Statistics, Nonparametric; Viral Load / drug effects
Sources: Web Of Science, ORCID
Added: August 6, 2018
2011 journal article
Connections between survey calibration estimators and semiparametric models for incomplete data discussion
International Statistical Review, 79(2), 221–223.
Source: NC State University Libraries
Added: August 6, 2018
2011 journal article
Improved Doubly Robust Estimation When Data Are Monotonely Coarsened, with Application to Longitudinal Studies with Dropout
BIOMETRICS, 67(2), 536–545.
author keywords: Coarsening at random; Discrete hazard; Dropout; Longitudinal data; Missing at random
MeSH headings : Acquired Immunodeficiency Syndrome; Biometry / methods; Computer Simulation; Humans; Longitudinal Studies; Models, Statistical; Statistical Distributions
Sources: Web Of Science, ORCID
Added: August 6, 2018
2011 journal article
Inference on treatment effects from a randomized clinical trial in the presence of premature treatment discontinuation: the SYNERGY trial
BIOSTATISTICS, 12(2), 258–269.
author keywords: Dynamic treatment regime; Inverse probability weighting; Potential outcomes; Proportional hazards model
MeSH headings : Acute Coronary Syndrome / drug therapy; Algorithms; Computer Simulation; Endpoint Determination; Enoxaparin / administration & dosage; Enoxaparin / adverse effects; Enoxaparin / therapeutic use; Hemorrhage / etiology; Heparin / administration & dosage; Heparin / adverse effects; Heparin / therapeutic use; Humans; Intention to Treat Analysis; Models, Statistical; Monte Carlo Method; Mortality; Multicenter Studies as Topic; Probability; Proportional Hazards Models; Randomized Controlled Trials as Topic / methods; Survival Analysis; Treatment Outcome; Withholding Treatment / statistics & numerical data
Sources: Web Of Science, ORCID
Added: August 6, 2018
2011 journal article
Semiparametric estimation of treatment effect with time-lagged response in the presence of informative censoring
LIFETIME DATA ANALYSIS, 17(4), 566–593.
author keywords: Informative censoring; Influence function; Logrank test; Nuisance tangent space; Proportional hazards model; Regular and asymptotically linear estimators
MeSH headings : Anti-HIV Agents / administration & dosage; Anti-HIV Agents / therapeutic use; CD4 Lymphocyte Count; Data Interpretation, Statistical; HIV / growth & development; HIV Infections / drug therapy; Humans; Models, Statistical; Randomized Controlled Trials as Topic / methods; Treatment Outcome
Source: Web Of Science
Added: August 6, 2018
2010 journal article
A Generalized Estimator of the Attributable Benefit of an Optimal Treatment Regime
BIOMETRICS, 66(2), 512–522.
author keywords: Attributable risk (AR); Causal inference; Influence function; Optimal treatment regime
MeSH headings : Algorithms; Cardiac Catheterization; Combined Modality Therapy; Coronary Artery Bypass; Humans; Methods; Observation; Precision Medicine / methods; Regression Analysis; Risk Assessment
Source: Web Of Science
Added: August 6, 2018
2010 journal article
Multiple Imputation Approaches for the Analysis of Dichotomized Responses in Longitudinal Studies with Missing Data
BIOMETRICS, 66(4), 1202–1208.
author keywords: Logistic regression; Missing data; Multiple imputation; Repeated measures
MeSH headings : Bayes Theorem; Biometry / methods; Humans; Likelihood Functions; Logistic Models; Longitudinal Studies / statistics & numerical data; Time Factors
Source: Web Of Science
Added: August 6, 2018
2009 journal article
Improving efficiency and robustness of the doubly robust estimator for a population mean with incomplete data
BIOMETRIKA, 96(3), 723–734.
author keywords: Causal inference; Enhanced propensity score model; Missing at random; No unmeasured confounders; Outcome regression
Sources: Web Of Science, ORCID
Added: August 6, 2018
2008 article
Covariate adjustment for two-sample treatment comparisons in randomized clinical trials: A principled yet flexible approach
Tsiatis, A. A., Davidian, M., Zhang, M., & Lu, X. (2008, October 15). STATISTICS IN MEDICINE, Vol. 27, pp. 4658–4677.
author keywords: baseline variables; clinical trials; covariate adjustment; efficiency; semiparametric theory; variable selection
MeSH headings : Algorithms; Data Interpretation, Statistical; Humans; Randomized Controlled Trials as Topic / statistics & numerical data; Sampling Studies; Statistics, Nonparametric; Treatment Outcome
Sources: Web Of Science, ORCID
Added: August 6, 2018
2008 journal article
Empirical estimation of life expectancy from large clinical trials: Use of left-truncated, right-censored survival analysis methodology
STATISTICS IN MEDICINE, 27(26), 5525–5555.
author keywords: life expectancy; cost-effectiveness; methods; clinical trials; survival
MeSH headings : Adult; Aged; Aged, 80 and over; Cardiovascular Diseases / economics; Cardiovascular Diseases / epidemiology; Cerebrovascular Disorders / economics; Cerebrovascular Disorders / epidemiology; Cohort Studies; Cost-Benefit Analysis; Female; Health Care Costs; Humans; Life Expectancy; Male; Markov Chains; Middle Aged; Models, Statistical; Observation; Proportional Hazards Models; Randomized Controlled Trials as Topic / methods; Survival Analysis
Source: Web Of Science
Added: August 6, 2018
2008 journal article
Improving efficiency of inferences in randomized clinical trials using auxiliary covariates
BIOMETRICS, 64(3), 707–715.
author keywords: covariate adjustment; hypothesis test; k-arm trial; Kruskal-Wallis test; log odds ratio; longitudinal data; semiparametric theory
MeSH headings : Acquired Immunodeficiency Syndrome / drug therapy; Analysis of Variance; Angina, Unstable / blood; Angina, Unstable / drug therapy; Anti-HIV Agents / therapeutic use; Anticoagulants / therapeutic use; Biometry / methods; Humans; Linear Models; Logistic Models; Models, Statistical; Monte Carlo Method; Odds Ratio; Platelet Glycoprotein GPIIb-IIIa Complex / metabolism; Randomized Controlled Trials as Topic / statistics & numerical data; Treatment Outcome
Sources: Web Of Science, ORCID
Added: August 6, 2018
2008 journal article
Improving the efficiency of the log-rank test using auxiliary covariates
BIOMETRIKA, 95(3), 679–694.
author keywords: efficient estimator; influence function; log-rank test; nuisance tangent space; proportional hazard model; regular and asymptotically linear estimator
Source: Web Of Science
Added: August 6, 2018
2008 journal article
Optimal two-stage group-sequential designs
JOURNAL OF STATISTICAL PLANNING AND INFERENCE, 138(2), 489–499.
author keywords: adaptive; backward induction; group-sequential; optimal design; two-stage
Source: Web Of Science
Added: August 6, 2018
2008 journal article
Quality of life with defibrillator therapy or amiodarone in heart failure
NEW ENGLAND JOURNAL OF MEDICINE, 359(10), 999–1008.
MeSH headings : Activities of Daily Living; Adult; Amiodarone / therapeutic use; Anti-Arrhythmia Agents / therapeutic use; Defibrillators, Implantable / adverse effects; Drug Therapy, Combination; Female; Follow-Up Studies; Heart Failure / drug therapy; Heart Failure / mortality; Heart Failure / psychology; Heart Failure / therapy; Humans; Male; Quality of Life; Survival Analysis
Source: Web Of Science
Added: August 6, 2018
2006 journal article
Adaptive two-stage designs in phase II clinical trials
STATISTICS IN MEDICINE, 25(19), 3382–3395.
author keywords: two-stage adaptive design; backward induction; Bayesian decision theory; simulated annealing
MeSH headings : Clinical Trials, Phase II as Topic / methods; Humans; Research Design; Sample Size
Source: Web Of Science
Added: August 6, 2018
2006 journal article
Cost-effectiveness of defibrillator therapy or amiodarone in chronic stable heart failure - Results from the Sudden Cardiac Death in Heart Failure Trial (SCD-HeFT)
CIRCULATION, 114(2), 135–142.
author keywords: amiodarone; defibrillators, implantable; heart failure, congestive; quality-adjusted life years; cost-benefit analysis
MeSH headings : Adult; Cost-Benefit Analysis; Death, Sudden, Cardiac / epidemiology; Defibrillators, Implantable / economics; Electroshock; Equipment Design; Heart Failure / surgery; Humans; Medical Records; Randomized Controlled Trials as Topic / economics; Retrospective Studies; Treatment Outcome; United States / epidemiology
Source: Web Of Science
Added: August 6, 2018
2006 article
Information-based monitoring of clinical trials
Tsiatis, A. A. (2006, October 15). STATISTICS IN MEDICINE, Vol. 25, pp. 3236–3244.
author keywords: group-sequential test; statistical information
MeSH headings : Clinical Trials Data Monitoring Committees; Clinical Trials as Topic / methods; Clinical Trials as Topic / standards; Clinical Trials as Topic / statistics & numerical data; Humans; Sample Size
Source: Web Of Science
Added: August 6, 2018
2006 journal article
On closed form semiparametric estimators for measurement error models
Statistica Sinica, 16(1), 183–193.
Source: NC State University Libraries
Added: August 6, 2018
2006 journal article
Semiparametric efficient estimation of survival distributions in two-stage randomisation designs in clinical trials with censored data
BIOMETRIKA, 93(1), 163–177.
author keywords: censoring; influence function; inverse probability weighted estimator; potential outcome; regular asymptotically linear estimator; two-stage design
Source: Web Of Science
Added: August 6, 2018
2006 book
Semiparametric theory and missing data
New York: Springer.
Source: NC State University Libraries
Added: August 6, 2018
2006 journal article
Semiparametric transformation models for the case-cohort study
BIOMETRIKA, 93(1), 207–214.
author keywords: case-cohort design; martingale; transformation model; weighted estimating equation
Source: Web Of Science
Added: August 6, 2018
2005 journal article
Comparison between two partial likelihood approaches for the competing risks model with missing cause of failure
LIFETIME DATA ANALYSIS, 11(1), 29–40.
author keywords: cause-specific hazard; martingale; missing at random; semiparametric efficiency
MeSH headings : Cause of Death; Humans; Life Tables; Likelihood Functions; Models, Statistical; Proportional Hazards Models; Risk; Risk Assessment; Sensitivity and Specificity; Survival Analysis; United States
Source: Web Of Science
Added: August 6, 2018
2005 journal article
Conducting economic evaluations alongside multinational clinical trials: Toward a research consensus
AMERICAN HEART JOURNAL, 149(3), 434–443.
MeSH headings : Clinical Trials as Topic / economics; Clinical Trials as Topic / methods; Clinical Trials as Topic / trends; Costs and Cost Analysis / classification; Forecasting; Health Care Costs / classification; Health Resources / economics; Humans; Internationality; Multicenter Studies as Topic / economics; Multicenter Studies as Topic / methods; Multicenter Studies as Topic / trends; Research Design; Resource Allocation / methods; Terminology as Topic; Treatment Outcome; United States
Source: Web Of Science
Added: August 6, 2018
2005 journal article
Locally efficient semiparametric estimators for generalized skew-elliptical distributions
JOURNAL OF THE AMERICAN STATISTICAL ASSOCIATION, 100(471), 980–989.
author keywords: generalized skew-elliptical distribution; influence function; nuisance tangent space; selection model; semiparametric efficiency
Source: Web Of Science
Added: August 6, 2018
2005 journal article
Locally-efficient robust estimation of haplotype-disease association in family-based studies
BIOMETRIKA, 92(3), 559–571.
author keywords: family-based association study; haplotype; nuisance parameter
Source: Web Of Science
Added: August 6, 2018
2005 journal article
Semiparametric estimation of treatment effect in a pretest-posttest study with missing data
Statistical Science, 20(3), 261–282.
Source: NC State University Libraries
Added: August 6, 2018
2005 journal article
Semiparametric estimators for the regression coefficients in the linear transformation competing risks model with missing cause of failure
BIOMETRIKA, 92(4), 875–891.
author keywords: cause-specific hazard; competing risks; doubly robust; inverse probability weighted; linear transformation model; missing at random
Source: Web Of Science
Added: August 6, 2018
2005 journal article
Semiparametric inference in observational duration-response studies, with duration possibly right-censored
BIOMETRIKA, 92(3), 605–618.
author keywords: confounding; infusion trial; missing data; survival analysis
Source: Web Of Science
Added: August 6, 2018
2005 article
Statistical issues arising in the Women's Health Initiative - Discussion
Tsiatis, A. A., & Davidian, M. (2005, December). BIOMETRICS, Vol. 61, pp. 933–935.
Sources: Web Of Science, ORCID
Added: August 6, 2018
2004 journal article
Differential Treatment Benefit of Platelet Glycoprotein IIb/IIIa Inhibition With Percutaneous Coronary Intervention Versus Medical Therapy for Acute Coronary Syndromes
Circulation, 109(5), 641–646.
author keywords: trials; glycoproteins; coronary disease
MeSH headings : Acute Disease; Aged; Combined Modality Therapy; Coronary Disease / drug therapy; Coronary Disease / surgery; Female; Humans; Male; Middle Aged; Myocardial Revascularization; Patient Selection; Platelet Glycoprotein GPIIb-IIIa Complex / antagonists & inhibitors; Randomized Controlled Trials as Topic; Research Design; Syndrome; Treatment Outcome
Sources: Web Of Science, Crossref, ORCID
Added: August 6, 2018
2004 journal article
Estimating mean response as a function of treatment duration in an observational study, where duration may be informatively censored
BIOMETRICS, 60(2), 315–323.
author keywords: censored covariates; censored treatment; confounding; infusion length; inverse weighting; observational study; propensity score; survival analysis
MeSH headings : Biometry; Clinical Protocols; Coronary Artery Disease / drug therapy; Data Interpretation, Statistical; Eptifibatide; Humans; Peptides / therapeutic use; Platelet Aggregation Inhibitors / therapeutic use; Randomized Controlled Trials as Topic / statistics & numerical data; Time Factors; Treatment Outcome
Source: Web Of Science
Added: August 6, 2018
2004 journal article
Joint modeling of longitudinal and time-to-event data: An overview
Statistica Sinica, 14(3), 809–834.
Source: NC State University Libraries
Added: August 6, 2018
2004 journal article
Locally efficient semiparametric estimators for functional measurement error models
Biometrika, 91(4), 835–848.
Source: NC State University Libraries
Added: August 6, 2018
2004 journal article
Marginal structural models for analyzing causal effects of time-dependent treatments: An application in perinatal epidemiology
AMERICAN JOURNAL OF EPIDEMIOLOGY, 159(10), 926–934.
author keywords: causality; confounding factors (epidemiology); epidemiologic methods; longitudinal studies; models, structural
MeSH headings : Adult; Anemia / diet therapy; Anemia / epidemiology; Anemia / prevention & control; Causality; Confounding Factors, Epidemiologic; Dietary Supplements; Epidemiologic Research Design; Female; Humans; Iron / administration & dosage; Logistic Models; Models, Statistical; North Carolina / epidemiology; Pregnancy; Pregnancy Complications, Hematologic / diet therapy; Pregnancy Complications, Hematologic / epidemiology; Pregnancy Complications, Hematologic / prevention & control; Random Allocation; Time Factors
Sources: Web Of Science, ORCID
Added: August 6, 2018
2004 journal article
Optimal duration of eptifibatide infusion in percutaneous coronary intervention (an ESPRIT Substudy)
AMERICAN JOURNAL OF CARDIOLOGY, 94(7), 926–929.
MeSH headings : Angioplasty, Balloon, Coronary; Biomarkers / blood; Coronary Disease / therapy; Creatine Kinase / blood; Creatine Kinase, MB Form; Double-Blind Method; Eptifibatide; Humans; Infusions, Intra-Arterial; Isoenzymes / blood; Myocardial Infarction / blood; Myocardial Infarction / etiology; Myocardial Infarction / mortality; North America / epidemiology; Peptides / therapeutic use; Platelet Aggregation Inhibitors / therapeutic use; Platelet Glycoprotein GPIIb-IIIa Complex / antagonists & inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex / therapeutic use; Postoperative Complications / blood; Postoperative Complications / etiology; Postoperative Complications / mortality; Survival Analysis; Time Factors; Treatment Outcome
Source: Web Of Science
Added: August 6, 2018
2004 journal article
Optimal estimator for the survival distribution and related quantities for treatment policies in two-stage randomization designs in clinical trials
BIOMETRICS, 60(1), 124–133.
author keywords: induction therapy; influence functions; intent-to-treat; inverse probability weighted estimator; maintenance therapy; missing data; potential outcomes; survival analysis
MeSH headings : Antineoplastic Agents / therapeutic use; Biometry; Granulocyte-Macrophage Colony-Stimulating Factor / therapeutic use; Humans; Leukemia, Myeloid, Acute / drug therapy; Leukemia, Myeloid, Acute / mortality; Linear Models; Models, Statistical; Nonlinear Dynamics; Randomized Controlled Trials as Topic / statistics & numerical data; Recombinant Proteins; Statistics, Nonparametric; Survival Analysis
Source: Web Of Science
Added: August 6, 2018
2004 journal article
The prognostic importance of comorbidity for mortality in patients with stable coronary artery disease
ACC Current Journal Review, 13(4), 11–12.
Source: Crossref
Added: August 28, 2020
2004 journal article
The prognostic importance of comorbidity for mortality in patients with stable coronary artery disease
Journal of the American College of Cardiology, 43(4), 576–582.
MeSH headings : Black People / statistics & numerical data; Cardiac Catheterization; Cohort Studies; Comorbidity; Coronary Artery Disease / epidemiology; Coronary Artery Disease / ethnology; Coronary Artery Disease / mortality; Databases, Factual / statistics & numerical data; Female; Follow-Up Studies; Humans; Male; Middle Aged; Prognosis; Proportional Hazards Models; Stroke Volume / physiology; Survival Analysis; Time Factors; Ventricular Function, Left / physiology; White People / statistics & numerical data
Source: Crossref
Added: August 28, 2020
2003 journal article
On the inefficiency of the adaptive design for monitoring clinical trials
BIOMETRIKA, 90(2), 367–378.
author keywords: adaptive design; group-sequential test; likelihood ratio test
Source: Web Of Science
Added: August 6, 2018
2003 journal article
Semiparametric estimation of treatment effect in a pretest-posttest study
BIOMETRICS, 59(4), 1046–1055.
author keywords: analysis of covariance; counterfactuals; influence function; inverse probability weighting; semiparametric model; t-test
MeSH headings : Antiviral Agents / therapeutic use; Biometry / methods; CD4 Lymphocyte Count; Clinical Trials as Topic; Computer Simulation; HIV Infections / drug therapy; Humans; Models, Statistical; Randomized Controlled Trials as Topic; Statistics, Nonparametric
Sources: Web Of Science, ORCID
Added: August 6, 2018
2002 journal article
A semiparametric likelihood approach to joint modeling of longitudinal and time-to-event data
BIOMETRICS, 58(4), 742–753.
author keywords: informative censoring; mixed model; proportional hazards; SNP density; survival
MeSH headings : Anti-HIV Agents / therapeutic use; Biometry / methods; Computer Simulation; Disease Progression; HIV Infections / drug therapy; Humans; Likelihood Functions; Longitudinal Studies; Monte Carlo Method; Proportional Hazards Models; Randomized Controlled Trials as Topic / methods
Sources: Web Of Science, ORCID
Added: August 6, 2018
2002 journal article
An estimator for the proportional hazards model with multiple longitudinal covariates measured with error
Biostatistics (Oxford, England), 3(4), 511–528.
Source: NC State University Libraries
Added: August 6, 2018
2002 journal article
Effects of insulin in relatives of patients with type 1 diabetes mellitus
New England Journal of Medicine, 346(22), 1685–1691.
Source: NC State University Libraries
Added: August 6, 2018
2002 journal article
Estimation of survival distributions of treatment policies in two-stage randomization designs in clinical trials
BIOMETRICS, 58(1), 48–57.
author keywords: induction therapy; intent to treat; inverse weighting; maintenance therapy; potential outcomes; survival analysis
MeSH headings : Aged; Computer Simulation; Granulocyte-Macrophage Colony-Stimulating Factor / therapeutic use; Humans; Leukemia, Myeloid, Acute / drug therapy; Models, Statistical; Randomized Controlled Trials as Topic / methods; Survival Analysis; Treatment Outcome
Sources: Web Of Science, ORCID
Added: August 6, 2018
2002 journal article
Median regression with censored cost data
BIOMETRICS, 58(3), 643–649.
author keywords: cost analysis; estimating equation; median regression; simulated annealing; survival analysis
MeSH headings : Biometry; Colorectal Neoplasms / economics; Colorectal Neoplasms / therapy; Costs and Cost Analysis / statistics & numerical data; Health Care Costs / statistics & numerical data; Humans; Models, Statistical; Regression Analysis
Source: Web Of Science
Added: August 6, 2018
2002 journal article
Multiple imputation methods for testing treatment differences in survival distributions with missing cause of failure
Biometrika, 89(1), 238–244.
Source: NC State University Libraries
Added: August 6, 2018
2001 journal article
A semiparametric estimator for the proportional hazards model with longitudinal covariates measured with error
BIOMETRIKA, 88(2), 447–458.
author keywords: conditional score; measurement error; mixed effects model; regression calibration; semiparametric; survival analysis
Source: Web Of Science
Added: August 6, 2018
2001 journal article
Causal inference on the difference of the restricted mean lifetime between two groups
BIOMETRICS, 57(4), 1030–1038.
author keywords: causal inference; Cox's proportional hazard model; martingale process; observational study; restricted lifetime; stochastic integral; survival analysis
MeSH headings : Biometry; Coronary Disease / mortality; Coronary Disease / therapy; Humans; Life Tables; Models, Statistical; Proportional Hazards Models; Stochastic Processes; Survival Analysis
Source: Web Of Science
Added: August 6, 2018
2001 journal article
Computationally simple accelerated failure time regression for interval censored data
BIOMETRIKA, 88(3), 703–711.
author keywords: AIDS; current status data; nonparametric maximum likelihood; survival analysis
Source: Web Of Science
Added: August 6, 2018
2001 journal article
Efficiency study of estimators for a treatment effect in a pretest-posttest trial
AMERICAN STATISTICIAN, 55(4), 314–321.
author keywords: analysis of covariance; GEE model; paired t test; semiparametric model; two-sample t test
Source: Web Of Science
Added: August 6, 2018
2001 journal article
Flexible sample size considerations using information-based interim monitoring
DRUG INFORMATION JOURNAL, 35(4), 1095–1112.
author keywords: sample size reestimation; information-based design and monitoring; adaptive design
Source: Web Of Science
Added: August 6, 2018
2001 journal article
Interim monitoring of group sequential trials using spending functions for the type I and type II error probabilities
DRUG INFORMATION JOURNAL, 35(4), 1113–1121.
author keywords: group sequential trials; information time; error spending function
Source: Web Of Science
Added: August 6, 2018
2001 journal article
Multiple imputation methods for estimating regression coefficients in the competing risks model with missing cause of failure
BIOMETRICS, 57(4), 1191–1197.
author keywords: cause-specific hazard; missing at random; partial likelihood
MeSH headings : Breast Neoplasms / metabolism; Breast Neoplasms / mortality; Breast Neoplasms / therapy; Cause of Death; Clinical Trials as Topic / statistics & numerical data; Female; Humans; Likelihood Functions; Models, Statistical; Neoplasms, Hormone-Dependent / metabolism; Neoplasms, Hormone-Dependent / mortality; Neoplasms, Hormone-Dependent / therapy; Proportional Hazards Models; Receptors, Estrogen / metabolism; Regression Analysis; Risk; Treatment Failure
Source: Web Of Science
Added: August 6, 2018
2001 journal article
Testing equality of survival functions of quality-adjusted lifetime
BIOMETRICS, 57(3), 861–867.
author keywords: counting processes; hypothesis test; martingale processes; quality of life; survival analysis
MeSH headings : Biometry; Breast Neoplasms / mortality; Breast Neoplasms / therapy; Clinical Trials as Topic / statistics & numerical data; Female; Humans; Models, Statistical; Quality-Adjusted Life Years; Survival Analysis
Source: Web Of Science
Added: August 6, 2018
2001 journal article
Using auxiliary time-dependent covariates to recover information in nonparametric testing with censored data
LIFETIME DATA ANALYSIS, 7(2), 125–141.
author keywords: Kaplan-Meier estimate; longitudinal; missing data; survival; two-sample test
MeSH headings : Data Interpretation, Statistical; Humans; Longitudinal Studies; Probability; Prognosis; Survival Analysis; United States
Source: Web Of Science
Added: August 6, 2018
2001 journal article
Utilizing propensity scores to estimate causal treatment effects with censored time-lagged data
BIOMETRICS, 57(4), 1207–1218.
author keywords: censoring; confounding; inverse weighting; Kaplan-Meier; observational study; propensity score; survival analysis
MeSH headings : Analysis of Variance; Biometry; Clinical Trials as Topic / statistics & numerical data; Coronary Disease / economics; Coronary Disease / therapy; Data Interpretation, Statistical; Health Care Costs / statistics & numerical data; Humans; Models, Statistical
Source: Web Of Science
Added: August 6, 2018
2000 journal article
Cost-effectiveness of platelet glycoprotein IIb/IIIa inhibition with eptifibatide in patients with non-ST-elevation acute coronary syndromes
CIRCULATION, 101(4), 366–371.
author keywords: coronary disease; cost-benefit analysis; glycoproteins; eptifibatide
MeSH headings : Angina, Unstable / drug therapy; Angina, Unstable / economics; Cost-Benefit Analysis; Eptifibatide; Female; Follow-Up Studies; Humans; Length of Stay; Male; Middle Aged; Myocardial Infarction / drug therapy; Myocardial Infarction / economics; Peptides / economics; Peptides / therapeutic use; Platelet Aggregation Inhibitors / economics; Platelet Aggregation Inhibitors / therapeutic use; Platelet Glycoprotein GPIIb-IIIa Complex / antagonists & inhibitors; Prospective Studies; Risk Factors; United States
Source: Web Of Science
Added: August 6, 2018
2000 journal article
Estimating medical costs with censored data
BIOMETRIKA, 87(2), 329–343.
author keywords: cost analysis; counting process; efficiency; martingale; missing data; semiparametrics; survival analysis
Source: Web Of Science
Added: August 6, 2018
2000 article
Estimating the distribution of quality-adjusted life with censored data
Tsiatis, A. A. (2000, April). AMERICAN HEART JOURNAL, Vol. 139, pp. S177–S181.
MeSH headings : Cardiovascular Agents / adverse effects; Cardiovascular Agents / therapeutic use; Data Interpretation, Statistical; Humans; Quality-Adjusted Life Years; Randomized Controlled Trials as Topic / statistics & numerical data; Survival Analysis
Source: Web Of Science
Added: August 6, 2018
2000 journal article
Human immunodeficiency virus type 1 RNA level and CD4 count as prognostic markers and surrogate end points: A meta-analysis
AIDS Research and Human Retroviruses, 16(12), 1123–1133.
Source: NC State University Libraries
Added: August 6, 2018
2000 journal article
Testing for differences in survival with delayed ascertainment
BIOMETRICS, 56(1), 145–153.
author keywords: ascertainment bias; counting process; logrank statistic; Martingale; U statistic
MeSH headings : Acquired Immunodeficiency Syndrome / drug therapy; Acquired Immunodeficiency Syndrome / immunology; Acquired Immunodeficiency Syndrome / mortality; Anti-HIV Agents / therapeutic use; Biometry; CD4 Lymphocyte Count; Clinical Trials as Topic / statistics & numerical data; Humans; Survival Analysis
Source: Web Of Science
Added: August 6, 2018
2000 journal article
Using conditional logistic regression to fit proportional odds models to interval censored data
BIOMETRICS, 56(2), 511–518.
author keywords: AIDS; current status data; nonparametric maximum likelihood; survival analysis
MeSH headings : Acquired Immunodeficiency Syndrome / drug therapy; Acquired Immunodeficiency Syndrome / immunology; Acquired Immunodeficiency Syndrome / mortality; Anti-HIV Agents / therapeutic use; Biometry / methods; CD4 Lymphocyte Count; Drug Therapy, Combination; Humans; Likelihood Functions; Models, Statistical; Regression Analysis; Statistics, Nonparametric; Survival Analysis; Zalcitabine / therapeutic use; Zidovudine / therapeutic use
Source: Web Of Science
Added: August 6, 2018
1999 journal article
Efficient estimation of the distribution of quality-adjusted survival time
BIOMETRICS, 55(4), 1101–1107.
author keywords: counting process; Martingale process; quality of life; semiparametric efficiency; survival analysis
MeSH headings : Biometry; Breast Neoplasms / mortality; Breast Neoplasms / therapy; Clinical Trials as Topic / statistics & numerical data; Computer Simulation; Female; Humans; Models, Statistical; Quality-Adjusted Life Years; Survival Analysis
Source: Web Of Science
Added: August 6, 2018
1998 journal article
Estimating the parameters in the Cox model when covariate variables are measured with error
BIOMETRICS, 54(4), 1407–1419.
author keywords: cumulative hazards; measurement error; nonparametric maximum likelihood; proportional hazards model; regression calibration; semiparametric method
Sources: Web Of Science, ORCID
Added: August 6, 2018
1998 journal article
Semiparametric efficient estimation in the generalized odds-rate class of regression models for right-censored time-to-event data
Lifetime Data Analysis, 4(4), 355–391.
MeSH headings : Biometry / methods; Clinical Trials as Topic; Data Interpretation, Statistical; Humans; Lung Neoplasms / radiotherapy; Models, Statistical; Odds Ratio; Randomized Controlled Trials as Topic; Regression Analysis; Time Factors; United States; United States Department of Veterans Affairs
Source: NC State University Libraries
Added: August 6, 2018
1998 journal article
Use of simulation and bootstrap in information-based group sequential studies
Statistics in Medicine, 17(1), 75–87.
Source: NC State University Libraries
Added: August 6, 2018
1997 journal article
A consistent estimator for the distribution of quality adjusted survival time
BIOMETRIKA, 84(2), 339–348.
author keywords: counting process; martingale process; quality of life; survival analysis
Source: Web Of Science
Added: August 6, 2018
1997 journal article
A joint model for survival and longitudinal data measured with error
BIOMETRICS, 53(1), 330–339.
author keywords: EM algorithm; longitudinal data; repeated measures; survival
Source: Web Of Science
Added: August 6, 2018
1997 journal article
Semiparametric efficiency and its implication on the design and analysis of group-sequential studies
JOURNAL OF THE AMERICAN STATISTICAL ASSOCIATION, 92(440), 1342–1350.
author keywords: independent increment; information-based design and monitoring; longitudinal study; maximum information trial; time-to-event study
Source: Web Of Science
Added: August 6, 2018
