@article{ning_yu_zhang_huang_tian_lin_niu_golden_hensley_threeton_et al._2021, title={A smartphone-read ultrasensitive and quantitative saliva test for COVID-19}, volume={7}, ISSN={["2375-2548"]}, DOI={10.1126/sciadv.abe3703}, abstractNote={An isolation-free smartphone-based saliva assay can diagnose COVID-19 cases and quantify viral load within 15 min.}, number={2}, journal={SCIENCE ADVANCES}, author={Ning, Bo and Yu, Tao and Zhang, Shengwei and Huang, Zhen and Tian, Di and Lin, Zhen and Niu, Alex and Golden, Nadia and Hensley, Krystle and Threeton, Breanna and et al.}, year={2021}, month={Jan} }
 @article{yu_zhang_matei_marx_beisel_wei_2021, title={Coupling smartphone and CRISPR-Cas12a for digital and multiplexed nucleic acid detection}, volume={7}, ISSN={["1547-5905"]}, url={https://doi.org/10.1002/aic.17365}, DOI={10.1002/aic.17365}, abstractNote={Abstract}, number={12}, journal={AICHE JOURNAL}, publisher={Wiley}, author={Yu, Tao and Zhang, Shengwei and Matei, Razvan and Marx, William and Beisel, Chase L. and Wei, Qingshan}, year={2021}, month={Jul} }
 @misc{li_yu_paul_fan_yang_wei_2020, title={Agricultural nanodiagnostics for plant diseases: recent advances and challenges}, volume={2}, ISSN={["2516-0230"]}, url={https://doi.org/10.1039/C9NA00724E}, DOI={10.1039/c9na00724e}, abstractNote={Engineered nanomaterials integrated with molecular assays or miniature sensing devices formed a promising nanodiagnostic tool box for plant diseases.}, number={8}, journal={NANOSCALE ADVANCES}, publisher={Royal Society of Chemistry (RSC)}, author={Li, Zheng and Yu, Tao and Paul, Rajesh and Fan, Jingyuan and Yang, Yuming and Wei, Qingshan}, year={2020}, month={Aug}, pages={3083–3094} }
 @article{li_zhang_yu_dai_wei_2019, title={Aptamer-Based Fluorescent Sensor Array for Multiplexed Detection of Cyanotoxins on a Smartphone}, volume={91}, ISSN={["1520-6882"]}, url={https://doi.org/10.1021/acs.analchem.9b00750}, DOI={10.1021/acs.analchem.9b00750}, abstractNote={Developing easy-to-use and miniaturized detectors is essential for in-field monitoring of environmentally hazardous substances, such as the cyanotoxins. We demonstrated a differential fluorescent sensor array made of aptamers and single-stranded DNA (ssDNA) dyes for multiplexed detection and discrimination of four common cyanotoxins with an ordinary smartphone within 5 minutes of reaction. The assay reagents were preloaded and dried in a microfluidic chip with a long shelf-life over 60 days. Upon the addition of analyte solutions, competitive binding of cyanotoxin to the specific aptamer-dye conjugate occurred. A zone-specific and concentration-dependent reduction in the green fluorescence was observed as a result of the aptamer conformation change. The aptasensors are fully optimized by quantification of their dissociation constants, tuning the stoichiometric ratios of reaction mixtures, and implementation of an internal intensity correction step. The fluorescent sensor array allowed for accurate identification and measurement of four important cyanotoxins, including anatoxin-a (ATX), cylindrospermopsin (CYN), nodularin (NOD), and microcystin-LR (MC-LR), in parallel, with the limit of detection (LOD) down to a few nanomolar (< 3 nM), which is close to the World Health Organization's guideline for the maximum concentration allowed in drinking water. The smartphone-based sensor platform also showed remarkable chemical specificity against potential interfering agents in water. The performance of the system was tested and validated with real lake water samples which were contaminated with trace levels of individual cyano-toxins as well as binary, ternary, and quaternary mixtures. Finally, a smartphone app interface has been developed for rapid on-site data processing and result display.}, number={16}, journal={ANALYTICAL CHEMISTRY}, publisher={American Chemical Society (ACS)}, author={Li, Zheng and Zhang, Shengwei and Yu, Tao and Dai, Zhiming and Wei, Qingshan}, year={2019}, month={Aug}, pages={10448–10457} }
 @misc{yu_wei_2018, title={Plasmonic molecular assays: Recent advances and applications for mobile health}, volume={11}, ISSN={["1998-0000"]}, url={http://www.scopus.com/inward/record.url?eid=2-s2.0-85048056782&partnerID=MN8TOARS}, DOI={10.1007/s12274-018-2094-9}, abstractNote={Plasmonics-based biosensing assays have been extensively employed for biomedical applications. Significant advancements in use of plasmonic assays for the construction of point-of-care (POC) diagnostic methods have been made to provide effective and urgent health care of patients, especially in resourcelimited settings. This rapidly progressive research area, centered on the unique surface plasmon resonance (SPR) properties of metallic nanostructures with exceptional absorption and scattering abilities, has greatly facilitated the development of cost-effective, sensitive, and rapid strategies for disease diagnostics and improving patient healthcare in both developed and developing worlds. This review highlights the recent advances and applications of plasmonic technologies for highly sensitive protein and nucleic acid biomarker detection. In particular, we focus on the implementation and penetration of various plasmonic technologies in conventional molecular diagnostic assays, and discuss how such modification has resulted in simpler, faster, and more sensitive alternatives that are suited for point-of-use. Finally, integration of plasmonic molecular assays with various portable POC platforms for mobile health applications are highlighted.}, number={10}, journal={NANO RESEARCH}, publisher={Springer Nature}, author={Yu, Tao and Wei, Qingshan}, year={2018}, month={Oct}, pages={5439–5473} }